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Alterations in cholesterol metabolism as a risk factor for developing Alzheimer’s disease: Potential novel targets for treatment
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The association between cholesterol homeostasis alterations and Alzheimer's disease onset and progression has been evident for many years.
“The association between cholesterol homeostasis alterations and AD onset and progression has been evident for many years [11,12,13].”
From ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis (2022) · cites this paper as [12]
Impaired cholesterol metabolism is linked to cognitive decline.
“In addition to contributing to nonalcoholic fatty liver disease, hyperlipidemia, hypertension and cardiovascular disease, impaired cholesterol metabolism is linked to cognitive decline50–52.”
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Metadata
- Authors
- Loera-Valencia, R., Goikolea, J., Parrado-Fernandez, C., Merino-Serrais, P., & Maioli, S.
- ORCID
- Loera-Valencia, Raúl
- Venue
- The Journal of Steroid Biochemistry and Molecular Biology
- Publisher
- Elsevier BV
- Published
- 2019-06
- Volume
- 190
- Pages
- 104-114
- ISSN
- 0960-0760
- Cited by
- 214
- References
- 23
- Language
- en
- Licence
- Funders
- Margaretha Af Ugglas Foundation, Stonhes Foundation and Foundation of Old Servants, the Swedish Medical Foundation
- Lindhés Advokatbyrå AB Foundation
- Karolinska Institutet Foundation for Research
- Swedish Research Council and StratNeuro
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