The lipid paradox in neuroprogressive disorders: Causes and consequences

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Ridker, P. M., Everett, B. M., Thuren, T., MacFadyen, J. G., Chang, W. H., Ballantyne, C., Fonseca, F., Nicolau, J., Koenig, W., Anker, S. D., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1707914 · Cited by 9,482 · see citing works

Acute-Phase Proteins and Other Systemic Responses to Inflammation

Gabay, C., & Kushner, I. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400607 · Cited by 6,734 · see citing works

Prostaglandins and Inflammation

Ricciotti, E., & FitzGerald, G. A. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.207449 · Cited by 3,852 · see citing works

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

Bhatt, D. L., Steg, P. G., Miller, M., Brinton, E. A., Jacobson, T. A., Ketchum, S. B., Doyle, R. T., Juliano, R. A., Jiao, L., Granowitz, C., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1812792 · Cited by 3,317 · see citing works

Pro-resolving lipid mediators are leads for resolution physiology

Serhan, C. N. (2014) · Nature · doi:10.1038/nature13479 · Cited by 3,041 · see citing works

Macrophages in atherosclerosis: a dynamic balance

Moore, K. J., Sheedy, F. J., & Fisher, E. A. (2013) · Nature reviews. Immunology · doi:10.1038/nri3520 · Cited by 2,559 · see citing works

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

Su, L.-J., Zhang, J.-H., Gomez, H., Murugan, R., Hong, X., Xu, D., Jiang, F., & Peng, Z.-Y. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/5080843 · Cited by 2,166 · see citing works

Lipid peroxidation in cell death

Gaschler, M. M., & Stockwell, B. R. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.10.086 · Cited by 1,852 · see citing works

Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: A large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls

Correll, C. U., Solmi, M., Veronese, N., Bortolato, B., Rosson, S., Santonastaso, P., Thapa‐Chhetri, N., Fornaro, M., Gallicchio, D., Collantoni, E., et al. (2017) · World Psychiatry · doi:10.1002/wps.20420 · Cited by 1,729 · see citing works

A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression.

Goldsmith, D. R., Rapaport, M. H., & Miller, B. J. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.3 · Cited by 1,683 · see citing works

Resolvins

Serhan, C. N., Hong, S., Gronert, K., Colgan, S. P., Devchand, P. R., Mirick, G., & Moussignac, R.-L. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020760 · Cited by 1,650 · see citing works

Heparan Sulfate ProteoglycansPreprint

Sarrazin, S., Lamanna, W. C., & Esko, J. D. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004952 · Cited by 1,524 · see citing works

Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host

Khovidhunkit, W., Kim, M.-S., Memon, R. A., Shigenaga, J. K., Moser, A. H., Feingold, K. R., & Grunfeld, C. (2004) · Journal of Lipid Research · doi:10.1194/jlr.r300019-jlr200 · Cited by 1,481 · see citing works

Cholesterol, inflammation and innate immunity.

Tall, A. R., & Yvan-Charvet, L. (2015) · Nature Reviews Immunology · doi:10.1038/nri3793 · Cited by 1,479 · see citing works

Lipid mediator class switching during acute inflammation: signals in resolution

Levy, B. D., Clish, C. B., Schmidt, B., Gronert, K., & Serhan, C. N. (2001) · Nature Immunology · doi:10.1038/89759 · Cited by 1,453 · see citing works

So depression is an inflammatory disease, but where does the inflammation come from?

Berk, M., Williams, L. J., Jacka, F. N., O’Neil, A., Pasco, J. A., Moylan, S., Allen, N. B., Stuart, A. L., Hayley, A. C., Byrne, M. L., et al. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-200 · Cited by 1,423 · see citing works

Omega‐3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

Calder, P. C. (2012) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04374.x · Cited by 1,351 · see citing works

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

Serhan, C. N., & Levy, B. D. (2018) · Journal of Clinical Investigation · doi:10.1172/jci97943 · Cited by 1,344 · see citing works

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

Bäck, M., Yurdagul, A., Tabas, I., Öörni, K., & Kovanen, P. T. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0169-2 · Cited by 1,341 · see citing works

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

Rayner, K. J., Suárez, Y., Dávalos, A., Parathath, S., Fitzgerald, M. L., Tamehiro, N., Fisher, E. A., Moore, K. J., & Fernández-Hernando, C. (2010) · Science · doi:10.1126/science.1189862 · Cited by 1,260 · see citing works

The Opposing Effects of N-3 and n-6 Fatty Acids

Schmitz, G., & Ecker, J. (2008) · Progress in Lipid Research · doi:10.1016/j.plipres.2007.12.004 · Cited by 1,245 · see citing works

Mitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways?

Son, Y., Cheong, Y.-K., Kim, N.-H., Chung, H.-T., Kang, D. G., & Pae, H.-O. (2011) · Journal of Signal Transduction · doi:10.1155/2011/792639 · Cited by 1,219 · see citing works

Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

Serhan, C. N., Clish, C. B., Brannon, J., Colgan, S. P., Chiang, N., & Gronert, K. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.8.1197 · Cited by 1,189 · see citing works

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

Maes, M., Galecki, P., Chang, Y. S., & Berk, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.05.004 · Cited by 1,140 · see citing works

A Test in Context: Lipoprotein(a)

Tsimikas, S. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.11.042 · Cited by 1,137 · see citing works

Leukocyte Behavior in Atherosclerosis, Myocardial Infarction, and Heart Failure

Świrski, F. K., & Nahrendorf, M. (2013) · Science · doi:10.1126/science.1230719 · Cited by 1,088 · see citing works

Role of homocysteine in the development of cardiovascular disease

Ganguly, P. K., & Alam, S. F. (2015) · Nutrition Journal · doi:10.1186/1475-2891-14-6 · Cited by 1,030 · see citing works

TNF and ROS crosstalk in inflammation

Blaser, H., Dostert, C., Mak, T. W., & Brenner, D. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.12.002 · Cited by 1,008 · see citing works

Bidirectional Relation Between Inflammation and Coagulation

Levi, M. M., van der Poll, T., & Buller, H. R. (2004) · Circulation · doi:10.1161/01.cir.0000131660.51520.9a · Cited by 942 · see citing works

An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases

Law, S.-H., Chan, M.-L., Marathe, G. K., Parveen, F., Chen, C.-H., & Ke, L.-Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051149 · Cited by 817 · see citing works

TNF-α-induced increase in intestinal epithelial tight junction permeability requires NF-κB activation

Ma, T., Iwamoto, G. K., Hoa, N., Akotia, V., Pedram, A., Boivin, M., & Said, H. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00173.2003 · Cited by 811 · see citing works

Endothelial dysfunction — A major mediator of diabetic vascular disease

Sena, C. M., Pereira, A. M., & Seiça, R. M. F. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.08.006 · Cited by 796 · see citing works

Epigenetic Control of Smooth Muscle Cell Differentiation and Phenotypic Switching in Vascular Development and Disease

Alexander, M. R., & Owens, G. K. (2011) · Annual Review of Physiology · doi:10.1146/annurev-physiol-012110-142315 · Cited by 771 · see citing works

The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk

Popa, C. D., Netea, M. G., van Riel, P. L. C. M., van der Meer, J. W. M., & Stalenhoef, A. F. H. (2007) · Journal of Lipid Research · doi:10.1194/jlr.r600021-jlr200 · Cited by 765 · see citing works

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

Calon, F., Lim, G. P., Yang, F., Morihara, T., Teter, B., Ubeda, O., Rostaing, P., Triller, A., Salem, N., Ashe, K. H., et al. (2004) · Neuron · doi:10.1016/j.neuron.2004.08.013 · Cited by 707 · see citing works

Association of<i>LPA</i>Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

Burgess, S., Ference, B. A., Staley, J. R., Freitag, D. F., Mason, A. M., Nielsen, S. F., Willeit, P., Young, R., Surendran, P., Karthikeyan, S., et al. (2018) · JAMA Cardiology · doi:10.1001/jamacardio.2018.1470 · Cited by 689 · see citing works

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

van der Valk, F. M., Bekkering, S., Kroon, J., Yeang, C., den Bossche, J. V., van Buul, J. D., Ravandi, A., Nederveen, A. J., Verberne, H. J., Scipione, C. A., et al. (2016) · Circulation · doi:10.1161/circulationaha.116.020838 · Cited by 684 · see citing works

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

Maes, M., Berk, M., Goehler, L., Song, C., Anderson, G., Gałecki, P., & Leonard, B. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-66 · Cited by 629 · see citing works

The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression.

Maes, M. H. J., Kubera, M., & Leunis, J. (2008) · PubMed · Cited by 607 · see citing works

Cytokine Alterations in Bipolar Disorder: A Meta-Analysis of 30 Studies

Modabbernia, A., Taslimi, S., Brietzke, E., & Ashrafi, M. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.007 · Cited by 596 · see citing works

Synopsis of arachidonic acid metabolism: A review

Hanna, V. S., & HAFEZ, E. A. A. (2018) · Journal of Advanced Research · doi:10.1016/j.jare.2018.03.005 · Cited by 595 · see citing works

Lipid paradox in rheumatoid arthritis: the impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease

Myasoedova, E., Crowson, C. S., Kremers, H. M., Roger, V. L., Fitz‐Gibbon, P. D., Therneau, T. M., & Gabriel, S. E. (2011) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2010.135871 · Cited by 589 · see citing works

Depletion of Omega-3 Fatty Acid Levels in Red Blood Cell Membranes of Depressive Patients

Peet, M., Murphy, B., Shay, J., & Horrobin, D. F. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00206-0 · Cited by 581 · see citing works

Lipoprotein(a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology

Nordestgaard, B. G., & Langsted, A. (2016) · Journal of Lipid Research · doi:10.1194/jlr.r071233 · Cited by 575 · see citing works

Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials

Willeit, P., Ridker, P. M., Nestel, P. J., Simes, J., Tonkin, A. M., Pedersen, T. R., Schwartz, G. G., Olsson, A. G., Colhoun, H. M., Kronenberg, F., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)31652-0 · Cited by 564 · see citing works

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

Dalli, J., & Serhan, C. N. (2012) · Blood · doi:10.1182/blood-2012-04-423525 · Cited by 556 · see citing works

Anti-inflammatory properties of a platelet-activating factor acetylhydrolase

Tjoelker, L. W., Wilder, C., Eberhardt, C., Stafforinit, D. M., Dietsch, G., Schimpf, B. A., Hooper, S., Trong, H. L., Cousens, L. S., Zimmerman, G. A., et al. (1995) · Nature · doi:10.1038/374549a0 · Cited by 525 · see citing works

Endothelial Dysfunction as a Target for Prevention of Cardiovascular Disease

Versari, D., Daghini, E., Virdis, A., Ghiadoni, L., & Taddei, S. (2009) · Diabetes Care · doi:10.2337/dc09-s330 · Cited by 520 · see citing works

Biochemistry and Physiology of Mammalian Secreted Phospholipases A₂

Lambeau, G., & Gelb, M. H. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.062405.154007 · Cited by 513 · see citing works

Statin therapy increases lipoprotein(a) levels

Tsimikas, S., Gordts, P. L. S. M., Nora, C., Yeang, C., & Witztum, J. L. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz310 · Cited by 512 · see citing works

Anti-Inflammatory and Proresolving Lipid Mediators

Serhan, C. N., Yacoubian, S., & Yang, R. (2008) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.151409 · Cited by 511 · see citing works

Intestinal Microbiota in Cardiovascular Health and Disease

Tang, W. H. W., Bäckhed, F., Landmesser, U., & Hazen, S. L. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.03.024 · Cited by 508 · see citing works

Depression and the risk of coronary heart disease: a meta-analysis of prospective cohort studies

Gan, Y., Gong, Y., Tong, X., Sun, H., Cong, Y., Dong, X., Wang, Y., Xu, X., Yin, X., Deng, J., et al. (2014) · BMC Psychiatry · doi:10.1186/s12888-014-0371-z · Cited by 502 · see citing works

Multiple Roles for Neutrophils in Atherosclerosis

Soehnlein, O. (2012) · Circulation Research · doi:10.1161/circresaha.111.257535 · Cited by 498 · see citing works

Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress

Seimon, T. A., Nadolski, M. J., Liao, X., Magallon, J., Nguyen, M. T., Feric, N. T., Koschinsky, M. L., Harkewicz, R., Witztum, J. L., Tsimikas, S., et al. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.09.010 · Cited by 478 · see citing works

Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

Ramji, D. P., & Davies, T. S. (2015) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2015.04.003 · Cited by 469 · see citing works

Small Dense Low‐Density Lipoprotein as Biomarker for Atherosclerotic Diseases

Ivanova, E. A., Myasoedova, V. A., Melnichenko, A. А., Grechko, A. V., & Orekhov, A. N. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/1273042 · Cited by 467 · see citing works

Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: Possible treatments targeting the TLR4 pathway

Lucas, K., & Maes, M. (2013) · Molecular Neurobiology · doi:10.1007/s12035-013-8425-7 · Cited by 466 · see citing works

Reactive Oxygen Species in the Activation of MAP Kinases

Son, Y. H., Kim, S.-D., Chung, H., & Pae, H. (2013) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-405881-1.00002-1 · Cited by 465 · see citing works

Lowered ω3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients

Maes, M. H. J., Christophe, A. B., Delanghe, J., Altamura, C. A., Neels, H. M., & Meltzer, H. Y. (1999) · Psychiatry Research · doi:10.1016/s0165-1781(99)00014-1 · Cited by 452 · see citing works

Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000–2014

Hayes, J. F., Marston, L., Walters, K., King, M. B., & Osborn, D. P. J. (2017) · British Journal of Psychiatry · doi:10.1192/bjp.bp.117.202606 · Cited by 451 · see citing works

Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut

Maes, M., Kubera, M., Leunis, J.-C., & Berk, M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.02.023 · Cited by 446 · see citing works

Lipoprotein-Associated Phospholipase A2 Activity Is Associated With Risk of Coronary Heart Disease and Ischemic Stroke

Oei, H.-H. S., van der Meer, I. M., Albert Hofman, D., Koudstaal, P. J., Stijnen, T., Breteler, M. M. B., & Witteman, J. C. M. (2005) · Circulation · doi:10.1161/01.cir.0000154553.12214.cd · Cited by 423 · see citing works

Comparison of cytokine levels in depressed, manic and euthymic patients with bipolar disorder

Brietzke, E., Stertz, L., Fernandes, B. S., Kauer-Sant’Anna, M., Mascarenhas, M., Escosteguy Vargas, A., Chies, J. A., & Kapczinski, F. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.12.001 · Cited by 423 · see citing works

Cytosolic phospholipase A2: physiological function and role in disease

Leslie, C. C. (2015) · Journal of Lipid Research · doi:10.1194/jlr.r057588 · Cited by 418 · see citing works

Fatty acid composition in major depression: decreased ω3 fractions in cholesteryl esters and increased C20:4ω6C20:5ω3 ratio in cholesteryl esters and phospholipids

Maes, M., Smith, R., Christophe, A., Cosyns, P., Desnyder, R., & Meltzer, H. (1996) · Journal of Affective Disorders · doi:10.1016/0165-0327(95)00092-5 · Cited by 417 · see citing works

Neutrophil Extracellular Traps Participate in Cardiovascular Diseases

Döring, Y., Libby, P., & Soehnlein, O. (2020) · Circulation Research · doi:10.1161/circresaha.120.315931 · Cited by 415 · see citing works

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

Fredman, G., Hellmann, J., Proto, J. D., Kuriakose, G., Colas, R. A., Dorweiler, B., Connolly, E. S., Solomon, R., Jones, D. M., Heyer, E. J., et al. (2016) · Nature Communications · doi:10.1038/ncomms12859 · Cited by 411 · see citing works

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

Bergmark, C., Dewan, A. K., Orsoni, A., Merki, E., Miller, E. R., Shin, M., Binder, C. J., Hörkkö, S., Krauss, R. M., Chapman, M. J., et al. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800174-jlr200 · Cited by 410 · see citing works

Efficacy of omega-3 PUFAs in depression: A meta-analysis

Liao, Y., Xie, B., Zhang, H., He, Q., Guo, L., Subramanieapillai, M., Fan, B., Lu, C., & McIntyre, R. S. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0515-5 · Cited by 404 · see citing works

The role of oxidized phospholipids in atherosclerosis

Berliner, J. A., Leitinger, N., & Tsimikas, S. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800074-jlr200 · Cited by 404 · see citing works

Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy

McLaren, J. E., Michael, D. R., Ashlin, T. G., & Ramji, D. P. (2011) · Progress in Lipid Research · doi:10.1016/j.plipres.2011.04.002 · Cited by 395 · see citing works

Microbial translocation, immune activation, and HIV disease

Klatt, N. R., Funderburg, N., & Brenchley, J. M. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.09.001 · Cited by 390 · see citing works

Platelets: bridging hemostasis, inflammation, and immunity

Jenne, C. N., Urrutia, R., & Kubes, P. (2013) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.12084 · Cited by 382 · see citing works

Bioactive lipids, inflammation and chronic diseases

Leuti, A., Fazio, D., Fava, M., Piccoli, A., Oddi, S., & Maccarrone, M. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.06.028 · Cited by 368 · see citing works

An abundant dysfunctional apolipoprotein A1 in human atheroma

Huang, Y. R., DiDonato, J. A., Levison, B. S., Schmitt, D., Li, L., Wu, Y., Buffa, J. A., Kim, T., Gerstenecker, G. S., Gu, X., et al. (2014) · Nature Medicine · doi:10.1038/nm.3459 · Cited by 363 · see citing works

Resolution phase lipid mediators of inflammation: agonists of resolution

Serhan, C. N., & Chiang, N. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.05.012 · Cited by 332 · see citing works

Neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in mood disorders: A meta-analysis

Mazza, M. G., Lucchi, S., Tringali, A. G. M., Rossetti, A., Botti, E. R., & Clerici, M. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.03.012 · Cited by 326 · see citing works

Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

Trpković, A., Resanović, I., Stanimirović, J., Radak, D. J., Mousa, S. A., Cenic-Milosevic, D., Jevremović, D., & Isenović, E. R. (2014) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2014.992063 · Cited by 322 · see citing works

Inflammation, not Cholesterol, Is a Cause of Chronic Disease

Τσούπρας, Α., Lordan, R., & Zabetakis, I. (2018) · Nutrients · doi:10.3390/nu10050604 · Cited by 321 · see citing works

Cytokine Tuning of Intestinal Epithelial Function

Andrews, C., McLean, M. H., & Durum, S. K. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01270 · Cited by 321 · see citing works

Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment

Choy, E., Ganeshalingam, K., Semb, A., Szekanecz, Z., & Nurmohamed, M. (2014) · Rheumatology · doi:10.1093/rheumatology/keu224 · Cited by 320 · see citing works

Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase

Tselepis, A. D., & Chapman, M. J. (2002) · Atherosclerosis Supplements · doi:10.1016/s1567-5688(02)00045-4 · Cited by 316 · see citing works

Mechanisms of homocysteine toxicity in humans

Perła‐Kaján, J., Twardowski, T., & Jakubowski, H. (2007) · Amino Acids · doi:10.1007/s00726-006-0432-9 · Cited by 314 · see citing works

Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro.

Serhan, C. N., & Sheppard, K.-A. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114503 · Cited by 314 · see citing works

Homocysteine Thiolactone and Protein Homocysteinylation in Human Endothelial Cells

Jakubowski, H., Zhang, L., Bardeguez, A. D., & Aviv, A. (2000) · Circulation Research · doi:10.1161/01.res.87.1.45 · Cited by 312 · see citing works

Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?

Boffa, M. B., & Koschinsky, M. L. (2016) · Journal of Lipid Research · doi:10.1194/jlr.r060582 · Cited by 309 · see citing works

The Role of the Microbial Metabolites Including Tryptophan Catabolites and Short Chain Fatty Acids in the Pathophysiology of Immune-Inflammatory and Neuroimmune Disease

Morris, G., Berk, M., Carvalho, A. F., Caso, J. R., Sanz, Y., Walder, K. R., & Maes, M. H. J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0004-2 · Cited by 307 · see citing works

The Influence of Dietary Fatty Acids on Immune Responses

Radzikowska, U., Rinaldi, A. O., Çelebi Sözener, Z., Karaguzel, D., Wojcik, M., Cypryk, K., Akdis, M., Akdis, C. A., & Sokolowska, M. (2019) · Nutrients · doi:10.3390/nu11122990 · Cited by 306 · see citing works

Effects of IL-1β, IL-6 and IL-8 on erythrocytes, platelets and clot viscoelasticity

Bester, J., & Pretorius, E. (2016) · Scientific Reports · doi:10.1038/srep32188 · Cited by 303 · see citing works

Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)

Thorp, E., Vaisar, T., Subramanian, M., Mautner, L., Blobel, C., & Tabas, I. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.263020 · Cited by 298 · see citing works

Reconstituted High-Density Lipoproteins Inhibit the Acute Pro-Oxidant and Proinflammatory Vascular Changes Induced by a Periarterial Collar in Normocholesterolemic Rabbits

Nicholls, S. J., Dusting, G. J., Cutri, B., Bao, S., Drummond, G. R., Rye, K., & Barter, P. J. (2005) · Circulation · doi:10.1161/01.cir.0000159351.95399.50 · Cited by 294 · see citing works

Prostaglandins and chronic inflammation

Aoki, T., & Narumiya, S. (2012) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2012.02.004 · Cited by 289 · see citing works

Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease

Boffa, M. B., & Koschinsky, M. L. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0153-2 · Cited by 289 · see citing works

DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation

Duvall, M. G., & Levy, B. D. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.11.001 · Cited by 287 · see citing works

Omega-3 for Bipolar Disorder: Meta-Analyses of Use in Mania and Bipolar Depression

Sarris, J., Mischoulon, D., & Schweitzer, I. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10r06710 · Cited by 284 · see citing works

Structure of HDL: Particle Subclasses and Molecular Components

Kontush, A., Lindahl, M. G., Lhomme, M., Calabresi, L., Chapman, M. J., & Davidson, W. S. (2014) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-09665-0_1 · Cited by 284 · see citing works

Homocysteine and cardiovascular disease: a review of the evidence

Wierzbicki, A. S. (2007) · Diabetes and Vascular Disease Research · doi:10.3132/dvdr.2007.033 · Cited by 284 · see citing works

Prostaglandin‐cytokine crosstalk in chronic inflammation

Yao, C., & Narumiya, S. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14530 · Cited by 280 · see citing works

Cytokine Alterations in Schizophrenia: An Updated Review

Momtazmanesh, S., Zare-Shahabadi, A., & Rezaei, N. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00892 · Cited by 277 · see citing works

Induction of Macrophage Foam Cell Formation byChlamydia pneumoniae

Kalayoglu, M. V., & Byrne, G. I. (1998) · The Journal of Infectious Diseases · doi:10.1086/514241 · Cited by 275 · see citing works

Elevated peripheral cytokines characterize a subgroup of people with schizophrenia displaying poor verbal fluency and reduced Broca’s area volume

Fillman, S. G., Weickert, T. W., Lenroot, R. K., Catts, S. V., Bruggemann, J. M., Catts, V. S., & Weickert, C. S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.90 · Cited by 270 · see citing works

Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

Huang, Y., Wu, Z., Riwanto, M., Gao, S., Levison, B. S., Gu, X., Fu, X., Wagner, M. A., Besler, C., Gerstenecker, G., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci67478 · Cited by 269 · see citing works

The microbiome, immunity, and schizophrenia and bipolar disorder.

Dickerson, F., Severance, E., & Yolken, R. (2017) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2016.12.010 · Cited by 268 · see citing works

Antioxidative activity of high-density lipoprotein (HDL): Mechanistic insights into potential clinical benefit

Brites, F. D., Martín, M., Guillas, I., & Kontush, A. (2017) · BBA Clinical · doi:10.1016/j.bbacli.2017.07.002 · Cited by 265 · see citing works

Modification of High Density Lipoprotein by Myeloperoxidase Generates a Pro-inflammatory Particle

Undurti, A., Huang, Y. R., Lupica, J. A., Smith, J. D., DiDonato, J. A., & Hazen, S. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.047605 · Cited by 263 · see citing works

Therapeutic options for 5-lipoxygenase inhibitors

Werz, O., & Steinhilber, D. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.05.009 · Cited by 261 · see citing works

Migration to Apoptotic “Find-me” Signals Is Mediated via the Phagocyte Receptor G2A

Peter, C., Waibel, M., Radu, C. G., Yang, L. V., Witte, O. N., Schulze-Osthoff, K., Wesselborg, S., & Lauber, K. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m706586200 · Cited by 258 · see citing works

Homocysteine and coronary atherosclerosis: from folate fortification to the recent clinical trials

Antoniades, C. A., Antonopoulos, A. S., Tousoulis, D., Marinou, K., & Stefanadis, C. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn515 · Cited by 258 · see citing works

Low-density lipoprotein size and cardiovascular risk assessment

Rizzo, M., & Berneis, K. K. (2005) · QJM · doi:10.1093/qjmed/hci154 · Cited by 257 · see citing works

Cytokines in bipolar disorder: A systematic review and meta-analysis

Munkholm, K., Vinberg, M., & Vedel Kessing, L. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.06.010 · Cited by 256 · see citing works

Lipoxin A 4 and aspirin-triggered 15-epi-lipoxin A 4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes

József, L., Zouki, C., Petasis, N. A., Serhan, C. N., & Filep, J. G. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202296999 · Cited by 254 · see citing works

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Cai, B., Thorp, E. B., Doran, A. C., Subramanian, M., Sansbury, B. E., Lin, C., Spite, M. R., Fredman, G., & Tabas, I. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1524292113 · Cited by 253 · see citing works

Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

Norling, L. V., Dalli, J., Flower, R. J., Serhan, C. N., & Perretti, M. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.249508 · Cited by 252 · see citing works

Oxidized Phospholipids, Lipoprotein(a), Lipoprotein-Associated Phospholipase A2 Activity, and 10-Year Cardiovascular Outcomes

Kiechl, S. J., Willeit, J., Mayr, M., Viehweider, B., Oberhollenzer, M., Kronenberg, F., Wiedermann, C. J., Oberthaler, S., Xu, Q., Witztum, J. L., et al. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.145805 · Cited by 249 · see citing works

Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a)

Leibundgut, G., Scipione, C. A., Yin, H., Schneider, M., Boffa, M. B., Green, S., Yang, X., Dennis, E. A., Witztum, J. L., Koschinsky, M. L., et al. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m040733 · Cited by 246 · see citing works

Effects of Inhibition of Interleukin-6 Signalling on Insulin Sensitivity and Lipoprotein (A) Levels in Human Subjects with Rheumatoid Diseases

Schultz, O., Oberhauser, F., Saech, J., Rubbert-Roth, A., Hahn, M., Krone, W., & Laudes, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0014328 · Cited by 244 · see citing works

Discordant patterns of bacterial translocation markers and implications for innate immune imbalances in schizophrenia

Severance, E. G., Gressitt, K. L., Stallings, C. R., Origoni, A. E., Khushalani, S., Leweke, F. M., Dickerson, F. B., & Yolken, R. H. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.05.018 · Cited by 243 · see citing works

Inflammation and Cardiovascular Disease

Fearon, W. F., & Fearon, D. T. (2008) · Circulation · doi:10.1161/circulationaha.108.772491 · Cited by 241 · see citing works

Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

Häkkinen, T., Luoma, J. S., Hiltunen, M., Macphee, C. H., Milliner, K. J., Patel, L., Rice, S. Q. J., Tew, D. G., Karkola, K. O., & Ylä‐Herttuala, S. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.12.2909 · Cited by 239 · see citing works

The role of intestinal microbiota in cardiovascular disease

Jin, M., Qian, Z., Yin, J., Xu, W., & Zhou, X. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14195 · Cited by 236 · see citing works

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

Chen, L., Liu, L., Yin, J., Luo, Y., & Huang, S. (2008) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2008.10.029 · Cited by 235 · see citing works

Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.

Takano, T., Clish, C. B., Gronert, K., Petasis, N. A., & Serhan, C. N. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1578 · Cited by 230 · see citing works

Small dense low density lipoprotein has increased affinity for LDL receptor-independent cell surface binding sites: a potential mechanism for increased atherogenicity

Galeano, N. F., Al-Haideri, M. T., Keyserman, F., Rumsey, S. C., & Deckelbaum, R. J. (1998) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32551-7 · Cited by 229 · see citing works

A new era of secreted phospholipase A2

Murakami, M., Sato, H., Miki, Y., Yamamoto, K., & Taketomi, Y. (2015) · Journal of Lipid Research · doi:10.1194/jlr.r058123 · Cited by 229 · see citing works

Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis

Caplice, N. M., Panetta, C. J., Peterson, T. E., Kleppe, L. S., Mueske, C. S., Kostner, G. M., Broze, G., & Simari, R. D. (2001) · Blood · doi:10.1182/blood.v98.10.2980 · Cited by 228 · see citing works

Tyrosine 192 in Apolipoprotein A-I Is the Major Site of Nitration and Chlorination by Myeloperoxidase, but Only Chlorination Markedly Impairs ABCA1-dependent Cholesterol Transport

Shao, B., Bergt, C., Fu, X., Green, P., Voss, J. C., Oda, M. N., Oram, J. F., & Heinecke, J. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411484200 · Cited by 227 · see citing works

Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes

Gudbjartsson, D. F., Þorgeirsson, G., Sulem, P., Helgadóttir, A., Gylfason, A., Saemundsdottir, J., Björnsson, E., Norddahl, G. L., Jónasdóttir, Á., Jónasdóttir, A., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.10.019 · Cited by 227 · see citing works

TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway

Al–Sadi, R., Guo, S., Ye, D., Rawat, M., & Ma, T. Y. (2016) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.12.016 · Cited by 224 · see citing works

Changes in the serum levels of inflammatory cytokines in antidepressant drug-naïve patients with major depression

Zou, W., Feng, R., & Yang, Y. (2018) · PLOS ONE · doi:10.1371/journal.pone.0197267 · Cited by 224 · see citing works

How Do Elevated Triglycerides and Low HDL-Cholesterol Affect Inflammation and Atherothrombosis?

Welty, F. K. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0400-4 · Cited by 221 · see citing works

Major depression is associated with lower omega-3 fatty acid levels in patients with recent acute coronary syndromes

Frasure‐Smith, N., Lespérance, F., & Julien, P. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.01.021 · Cited by 220 · see citing works

Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo

Chen, K., Nishi, H., Travers, R. J., Tsuboi, N., Martinod, K., Wagner, D. D., Stan, R. V., Croce, K., & Mayadas, T. N. (2012) · Blood · doi:10.1182/blood-2011-12-401133 · Cited by 218 · see citing works

Lysophosphatidic acid as a lipid mediator with multiple biological actions

Aikawa, S., Hashimoto, T., Kano, K., & Aoki, J. (2014) · The Journal of Biochemistry · doi:10.1093/jb/mvu077 · Cited by 215 · see citing works

Bridging the Gap between Gut Microbial Dysbiosis and Cardiovascular Diseases

Lau, K., Srivatsav, V., Rizwan, A., Nashed, A., Liu, R., Shen, R. D., & Akhtar, M. (2017) · Nutrients · doi:10.3390/nu9080859 · Cited by 214 · see citing works

Neutrophils in Atherosclerosis

Döring, Y., Drechsler, M. D., Soehnlein, O., & Weber, C. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.303564 · Cited by 208 · see citing works

15-Epi-lipoxin A4 Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

Kebir, D. E., József, L., Pan, W., Wang, L., Petasis, N. A., Serhan, C. N., & Filep, J. G. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200810-1601oc · Cited by 206 · see citing works

Aspirin-Triggered Lipoxin and Resolvin E1 Modulate Vascular Smooth Muscle Phenotype and Correlate with Peripheral Atherosclerosis

Ho, K. J., Spite, M., Owens, C. D., Lancero, H., Kroemer, A. H. K., Pande, R., Creager, M. A., Serhan, C. N., & Conte, M. S. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.091082 · Cited by 204 · see citing works

Regulation of PPARγ function by TNF-α

Ye, J. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.07.068 · Cited by 198 · see citing works

Oxidized Phospholipids Predict the Presence and Progression of Carotid and Femoral Atherosclerosis and Symptomatic Cardiovascular Disease

Tsimikas, S., Kiechl, S. J., Willeit, J., Mayr, M., Miller, E. R., Kronenberg, F., Xu, Q., Bergmark, C., Weger, S., Oberhollenzer, F., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.03.001 · Cited by 196 · see citing works

Systemic Inflammatory Response and Atherosclerosis: The Paradigm of Chronic Inflammatory Rheumatic Diseases

Arida, A., Protogerou, A. D., Kitas, G. D., & Sfikakis, P. P. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19071890 · Cited by 196 · see citing works

Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B 4 synthesis by inhibiting a calcium-activated kinase pathway

Fredman, G., Özcan, L., Spolitu, S., Hellmann, J. L., Spite, M. R., Backs, J., & Tabas, I. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410851111 · Cited by 193 · see citing works

Depression and the Risk of Myocardial Infarction and Coronary Death

Wu, Q. F., & Kling, J. M. (2016) · Medicine · doi:10.1097/md.0000000000002815 · Cited by 193 · see citing works

Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I

Shao, B., Cavigiolio, G., Brot, N., Oda, M. N., & Heinecke, J. W. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802025105 · Cited by 189 · see citing works

Evidence Supporting a Key Role of Lp-PLA2-Generated Lysophosphatidylcholine in Human Atherosclerotic Plaque Inflammation

Gonçalves, I., Edsfeldt, A., Ko, N. Y., Grufman, H., Berg, K. E., Björkbacka, H., Nitulescu, M., Persson, A. F., Nilsson, M., Prehn, C. P., et al. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.249854 · Cited by 188 · see citing works

Hyperhomocysteinemia Decreases Circulating High-Density Lipoprotein by Inhibiting Apolipoprotein A-I Protein Synthesis and Enhancing HDL Cholesterol Clearance

Liao, D., Tan, H., Hui, R., Li, Z., Jiang, X., Gaubatz, J. W., Yang, F., Durante, W., Chan, L., Schafer, A. I., et al. (2006) · Circulation Research · doi:10.1161/01.res.0000242559.42077.22 · Cited by 186 · see citing works

Nutraceutical therapies for atherosclerosis

Moss, J. W. E., & Ramji, D. P. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.103 · Cited by 186 · see citing works

Enhanced oxidative susceptibility and reduced antioxidant content of metabolic precursors of small, dense low-density lipoproteins

Tribble, D. L., Rizzo, M., Chait, A., Lewis, D. M., Blanche, P. J., & Krauss, R. M. (2001) · The American Journal of Medicine · doi:10.1016/s0002-9343(00)00700-2 · Cited by 185 · see citing works

Association Between Lipoprotein-Associated Phospholipase A2 and Cardiovascular Disease: A Systematic Review

Garza, C. A., Montori, V. M., McConnell, J. P., Somers, V. K., Kullo, I. J., & López-Jiménez, F. A. (2007) · Mayo Clinic Proceedings · doi:10.4065/82.2.159 · Cited by 182 · see citing works

Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A

Yang, L. V., Radu, C. G., Wang, L., Riedinger, M., & Witte, O. N. (2004) · Blood · doi:10.1182/blood-2004-05-1916 · Cited by 180 · see citing works

Secretory phospholipase A2 enzymes as pharmacological targets for treatment of disease

Quach, N. D., Arnold, R. D., & Cummings, B. S. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.05.022 · Cited by 180 · see citing works

Lipoprotein(a) metabolism: Potential sites for therapeutic targets

Hoover-Plow, J. L., & Huang, M. (2012) · Metabolism · doi:10.1016/j.metabol.2012.07.024 · Cited by 175 · see citing works

Groups IV, V, and X Phospholipases A2s in Human Neutrophils

Degousée, N., Ghomashchi, F., Stefanski, E., Singer, A. G., Smart, B. P., Borregaard, N., Reithmeier, R., Lindsay, T. F., Lichtenberger, C., Reinisch, W., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109083200 · Cited by 175 · see citing works

IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans

Müller, N., Schulte, D. M., Türk, K., Freitag‐Wolf, S., Hampe, J., Zeuner, R. A., Schröder, J. O., Gouni‐Berthold, I., Berthold, H. K., Krone, W., et al. (2015) · Journal of Lipid Research · doi:10.1194/jlr.p052209 · Cited by 174 · see citing works

Boosting Inflammation Resolution in Atherosclerosis

Fredman, G., & Tabas, I. A. (2017) · American Journal Of Pathology · doi:10.1016/j.ajpath.2017.01.018 · Cited by 173 · see citing works

Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formation

Funk, J. L., Feingold, K. R., Moser, A. H., & Grünfeld, C. (1993) · Atherosclerosis · doi:10.1016/0021-9150(93)90224-i · Cited by 172 · see citing works

Co-compartmentalization of MAP kinases and cytosolic phospholipase A2 at cytoplasmic arachidonate-rich lipid bodies.

Yu, W., Bozza, P. T., Tzizik, D. M., Gray, J. P., Cassarà, J., Dvořàk, A. M., & Weller, P. F. (1998) · Europe PMC (PubMed Central) · Cited by 171 · see citing works

Using blood cytokine measures to define high inflammatory biotype of schizophrenia and schizoaffective disorder

Boerrigter, D., Weickert, T. W., Lenroot, R., O׳Donnell, M., Galletly, C. A., Liu, D., Burgess, M., Cadiz, R., Jacomb, I., Catts, V. S., et al. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-0962-y · Cited by 171 · see citing works

Lipoprotein-Associated and Secreted Phospholipases A 2 in Cardiovascular Disease

Mallat, Z., Lambeau, G. J., & Tedgui, A. (2010) · Circulation · doi:10.1161/circulationaha.110.936393 · Cited by 170 · see citing works

Cholesterol and triglyceride levels in first-episode psychosis: systematic review and meta-analysis

Pillinger, T., Beck, K., Stubbs, B., & Howes, O. D. (2017) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.117.200907 · Cited by 170 · see citing works

Effect of inflammation on HDL structure and function

Feingold, K. R., & Grünfeld, C. (2016) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000333 · Cited by 170 · see citing works

Modulation of Intestinal Epithelial Permeability by Plasma from Patients with Crohn’s Disease in a Three-dimensional Cell Culture Model

Xu, P., Elamin, E. E., Elizalde, M., Bours, P. H. A., Pierik, M. J., Masclee, A., & Jonkers, D. M. A. E. (2019) · Scientific Reports · doi:10.1038/s41598-018-38322-8 · Cited by 168 · see citing works

Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease

Pirault, J., & Bäck, M. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01273 · Cited by 167 · see citing works

The Atherogenic Role of Circulating Modified Lipids in Atherosclerosis

Summerhill, V. I., Grechko, A. V., Yet, S., Sobenin, I. A., & Orekhov, A. N. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143561 · Cited by 167 · see citing works

Lipoprotein(a) the Insurgent: A New Insight into the Structure, Function, Metabolism, Pathogenicity, and Medications Affecting Lipoprotein(a) Molecule

Jawi, M., Frohlich, J. J., & Chan, S. (2020) · Journal of Lipids · doi:10.1155/2020/3491764 · Cited by 164 · see citing works

Elevated Homocysteine Reduces Apolipoprotein A-I Expression in Hyperhomocysteinemic Mice and in Males With Coronary Artery Disease

Mikael, L. G., Genest, J. J., & Rozen, R. R. (2006) · Circulation Research · doi:10.1161/01.res.0000204825.66410.0b · Cited by 163 · see citing works

Lipoprotein-Associated Phospholipase A2 Activity Is a Marker of Small, Dense LDL Particles in Human Plasma

Gazi, I. F., Lourida, E. S., Filippatos, T. D., Tsimihodimos, V., Elisaf, M., & Tselepis, A. D. (2005) · Clinical Chemistry · doi:10.1373/clinchem.2005.058404 · Cited by 162 · see citing works

Lipoprotein Subfractions in Metabolic Syndrome and Obesity: Clinical Significance and Therapeutic Approaches

Nikolić, D., Katsiki, N., Montalto, G., Isenović, E. R., Mikhailidis, D. P., & Rizzo, M. (2013) · Nutrients · doi:10.3390/nu5030928 · Cited by 160 · see citing works

Comparative Safety of Interleukin-1 Blockade With Anakinra in Patients With ST-Segment Elevation Acute Myocardial Infarction (from the VCU-ART and VCU-ART2 Pilot Studies)

Abbate, A., Kontos, M. C., Abouzaki, N. A., Melchior, R. D., Thomas, C., Tassell, B. W. V., Oddi, C., Carbone, S., Trankle, C. R., Roberts, C. S., et al. (2014) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2014.11.003 · Cited by 160 · see citing works

Protein S -Nitrosylation as a Therapeutic Target for Neurodegenerative Diseases

Nakamura, T., & Lipton, S. A. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.10.002 · Cited by 160 · see citing works

Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: a systematic review

Garza, C. A., Montori, V. M., McConnell, J. P., Somers, V. K., Kullo, I. J., & Lopez-Jimenez, F. (2007) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)60992-0 · Cited by 159 · see citing works

Methionine Adenosyltransferase S-Nitrosylation Is Regulated by the Basic and Acidic Amino Acids Surrounding the Target Thiol

Pérez-Mato, I., Castro, C., Ruiz, F. A., Corrales, F. J., & Mato, J. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.24.17075 · Cited by 159 · see citing works

Molecular Basis of the Interaction between Plasma Platelet-activating Factor Acetylhydrolase and Low Density Lipoprotein

Stafforini, D. M., Tjoelker, L. W., McCormick, S. P. A., Vaitkus, D., McIntyre, T. M., Gray, P. W., Young, S. G., & Prescott, S. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.11.7018 · Cited by 159 · see citing works

HDL3-Mediated Inactivation of LDL-Associated Phospholipid Hydroperoxides Is Determined by the Redox Status of Apolipoprotein A-I and HDL Particle Surface Lipid Rigidity

Zerrad-Saadi, A., Thérond, P., Chantepie, S., Couturier, M., Rye, K., Chapman, M. J., & Kontush, A. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.194555 · Cited by 159 · see citing works

Lipid Peroxidation in Atherosclerotic Cardiovascular Diseases

Gianazza, E., Brioschi, M., Fernandez, A. M., Casalnuovo, F., Altomare, A., Aldini, G., & Banfi, C. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7955 · Cited by 158 · see citing works

Neutrophil&amp;ndash;lymphocyte ratio in patients with major depressive disorder undergoing no pharmacological therapy

Atli, A., Demir, S., Bulut, M., Okan İbiloğlu, A., Güneş, M., Kaya, M., Demirpençe, Ö., & Sır, A. (2015) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s89470 · Cited by 156 · see citing works

Potent Modification of Low Density Lipoprotein by Group X Secretory Phospholipase A2 Is Linked to Macrophage Foam Cell Formation

Hanasaki, K., Yamada, K., Yamamoto, S., Ishimoto, Y., Saiga, A., Ono, T., Ikeda, M., Notoya, M., Kamitani, S., & Arita, H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202867200 · Cited by 156 · see citing works

Homocysteine: Role and implications in atherosclerosis

Guthikonda, S., & Haynes, W. G. (2006) · Current Atherosclerosis Reports · doi:10.1007/s11883-006-0046-4 · Cited by 156 · see citing works

The composition and metabolism of large and small LDL

Diffenderfer, M. R., & Schaefer, E. J. (2014) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000067 · Cited by 155 · see citing works

Modulation of the inflammatory response to chitosan through M2 macrophage polarization using pro-resolution mediators

Vasconcelos, D. P., Costa, M. M., Amaral, I. F., Barbosa, M. A., Águas, A. P., & Barbosa, J. N. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.10.035 · Cited by 153 · see citing works

Phospholipase A 2 regulates eicosanoid class switching during inflammasome activation

Norris, P. C., Gosselin, D., Reichart, D. R., Glass, C. K., & Dennis, E. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1404372111 · Cited by 152 · see citing works

Aspirin-triggered proresolving mediators stimulate resolution in cancer

Gilligan, M. M., Gartung, A., Sulciner, M. L., Norris, P. C., Sukhatme, V. P., Bielenberg, D. R., Huang, S., Kieran, M. W., Serhan, C. N., & Panigrahy, D. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1804000116 · Cited by 152 · see citing works

Lipid profile disturbances in antipsychotic-naive patients with first-episode non-affective psychosis: A systematic review and meta-analysis

Misiak, B., Stańczykiewicz, B., Łaczmański, Ł., & Frydecka, D. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.03.031 · Cited by 151 · see citing works

Homocysteine levels in schizophrenia and affective disorders—focus on cognition

Moustafa, A. A., Hewedi, D. H., Eissa, A. M., Frydecka, D., & Misiak, B. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00343 · Cited by 149 · see citing works

A comparison of the neutrophil-lymphocyte, platelet-lymphocyte and monocyte-lymphocyte ratios in schizophrenia and bipolar disorder patients – a retrospective file review

Özdin, S., Sarisoy, G., & Böke, Ö. (2017) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2017.1340517 · Cited by 148 · see citing works

Gender differences in lipoprotein metabolism and dietary response: Basis in hormonal differences and implications for cardiovascular disease

Knopp, R. H., Paramsothy, P., Retzlaff, B. M., Fish, B., Walden, C., Dowdy, A., Tsunehara, C., Aikawa, K., & Cheung, M. C. (2005) · Current Atherosclerosis Reports · doi:10.1007/s11883-005-0065-6 · Cited by 148 · see citing works

Leukotriene B4 enhances the activity of nuclear factor- B pathway through BLT1 and BLT2 receptors in atherosclerosis

Sánchez-Galán, E., Gómez‐Hernández, A., Vidal, C., Martı́n-Ventura, J. L., Blanco‐Colio, L. M., Munoz-Garcia, B., Ortega, L. M., Egido, J., & Tuñón, J. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn277 · Cited by 145 · see citing works

Increased plasma peroxides and serum oxidized low density lipoprotein antibodies in major depression: Markers that further explain the higher incidence of neurodegeneration and coronary artery disease

Maes, M. H. J., Mihaylova, I., Kubera, M., Uytterhoeven, M., Vrydags, N., & Bosmans, E. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.12.014 · Cited by 144 · see citing works

Leaky brain in neurological and psychiatric disorders: Drivers and consequences

Morris, G., Fernandes, B. S., Puri, B. K., Walker, A. J., Carvalho, A. F., & Berk, M. (2018) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867418796955 · Cited by 144 · see citing works

Platelet Factor 4 Enhances the Binding of Oxidized Low-density Lipoprotein to Vascular Wall Cells

Nassar, T., Sachais, B. S., Akkawi, S., Kowalska, M. A., Bdeir, K. H., Leitersdorf, E., Hiss, E., Ziporen, L., Aviram, M., Cines, D. B., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m208894200 · Cited by 143 · see citing works

MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles

Menzel, N., Fischl, W., Hueging, K., Bankwitz, D., Frentzen, A., Haid, S., Gentzsch, J., Kaderali, L., Bartenschlager, R. F. W., & Pietschmann, T. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002829 · Cited by 142 · see citing works

Lipopolysaccharide Down Regulates Both Scavenger Receptor B1 and ATP Binding Cassette Transporter A1 in RAW Cells

Baranova, I. N., Vishnyakova, T. G., Bocharov, A. V., Chen, Z., Remaley, A. T., Stonik, J. A., Eggerman, T. L., & Patterson, A. P. (2002) · Infection and Immunity · doi:10.1128/iai.70.6.2995-3003.2002 · Cited by 142 · see citing works

Oxidative stress, polyunsaturated fatty acidsderived oxidation products and bisretinoids as potential inducers of CNS diseases: focus on age-related macular degeneration

Nowak, J. Z. (2013) · Pharmacological Reports · doi:10.1016/s1734-1140(13)71005-3 · Cited by 141 · see citing works

ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase, and Increased Binding to Biglycan

Hiukka, A., Ståhlman, M., Pettersson, C., Levin, M. C., Adiels, M., Teneberg, S., Leinonen, E. S., Hultén, L. M., Wiklund, O., Orešič, M., et al. (2009) · Diabetes · doi:10.2337/db09-0206 · Cited by 141 · see citing works

The expression of genes encoding for COX-2, MPO, iNOS, and sPLA2-IIA in patients with recurrent depressive disorder

Gałecki, P., Gałecka, E., Maes, M., Chamielec, M., Orzechowska, A., Bobińska, K., Lewiński, A., & Szemraj, J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.01.016 · Cited by 141 · see citing works

Reciprocal and Coordinate Regulation of Serum Amyloid A Versus Apolipoprotein A-I and Paraoxonase-1 by Inflammation in Murine Hepatocytes

Han, C. Y., Chiba, T., Campbell, J. S., Fausto, N., Chaisson, M. L., Orasanu, G., Plutzky, J., & Chait, A. (2006) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000227472.70734.ad · Cited by 140 · see citing works

The effect of probiotic and synbiotic supplementation on biomarkers of inflammation and oxidative stress in diabetic patients: A systematic review and meta-analysis of randomized controlled trials

Zheng, H., Guo, J., Jia, Q., Huang, Y., Huang, W., Zhang, W., Zhang, F., Liu, W. J., & Wang, Y. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.02.016 · Cited by 140 · see citing works

MAPK- Kinases as Nucleo-Cytoplasmic Shuttles for PPARγ

Burgermeister, E., & Seger, R. (2007) · Cell Cycle · doi:10.4161/cc.6.13.4453 · Cited by 138 · see citing works

Hypoxic and Hyperoxic Breathing as a Complement to Low-Intensity Physical Exercise Programs: A Proof-of-Principle Study

Balestra, C., Lambrechts, K., Mrakic‐Sposta, S., Vezzoli, A., Lévénez, M., Germonpré, P., Virgili, F., Bosco, G., & Lafère, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179600 · Cited by 38 · see citing works

Relationship between Brain Metabolic Disorders and Cognitive Impairment: LDL Receptor Defect

Hong, D.-Y., Lee, D.-H., Lee, J., Lee, E.-C., Park, S.-W., Lee, M. R., & Oh, J. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158384 · Cited by 37 · see citing works

The pharmacological bases for repurposing statins in depression: a review of mechanistic studies

Giorgi, R. D., Pesci, N. R., Rosso, G., Maina, G., Cowen, P. J., & Harmer, C. J. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02533-z · Cited by 29 · see citing works

Lipoprotein oxidation may underlie the paradoxical association of low cholesterol with coronary atherosclerotic risk in rheumatoid arthritis

Karpouzas, G. A., Ormseth, S. R., Ronda, N., Hernández, E., & Budoff, M. J. (2022) · Journal of Autoimmunity · doi:10.1016/j.jaut.2022.102815 · Cited by 22 · see citing works

Shared postulations between bipolar disorder and polycystic ovary syndrome pathologies

Dai, W., Liu, J., Qiu, Y., Teng, Z., Li, S., Huang, J., Xiang, H., Tang, H., Wang, B., Chen, J., et al. (2021) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2021.110498 · Cited by 15 · see citing works

Inflammation and lipid metabolism as potential biomarkers of memory impairment across type 2 diabetes mellitus and severe mental disorders

Sánchez‐Ortí, J. V., Correa‐Ghisays, P., Balanzá‐Martínez, V., Selva‐Vera, G., Vila‐Francés, J., Magdalena‐Benedito, R., Valenzuela, C. S. M., Víctor, V. M., Escribano‐López, I., Hernández‐Mijares, A., et al. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110817 · Cited by 15 · see citing works

Albumin and Associated Biomarkers in Severe Neuropsychiatric Disorders: Acute-Phase Schizophrenia and Bipolar Disorder

Xu, H., Zheng, L., Wang, L., Gao, H., Wei, Y., & Chen, J. (2023) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s423399 · Cited by 13 · see citing works

Associations between lipid parameters and depression with the moderating role of inflammation: Network analyses of 87,636 UK Biobank participants

Li, P., Zhang, H., Ma, J., Wang, J., Lv, S., Zhao, X., Yang, X., Luo, Y., Tao, L., Guo, X., et al. (2025) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2025.107543 · Cited by 6 · see citing works

Network analysis of plasma proteomes in affective disorders

Rhee, S. J., Shin, D., Shin, D., Song, Y., Joo, E.-J., Jung, H. Y., Roh, S., Lee, S.-H., Kim, H.-Y., Bang, M., et al. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02485-4 · Cited by 8 · see citing works

Inflammation molecular network alterations in a depressive-like primate model

Bu, S., Wang, Q., Zhang, G., Zhang, Z., Dai, J., & Zhang, Z. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.03.021 · Cited by 5 · see citing works

Differences in plasma lipoprotein profiles between patients with chronic peripheral neuropathic pain and healthy controls: an exploratory pilot study

Jönsson, M., Bäckryd, E., Jonasson, L., Gerdle, B. U. C., & Ghafouri, B. (2022) · PAIN Reports · doi:10.1097/pr9.0000000000001036 · Cited by 5 · see citing works

Elevated levels of apolipoprotein A4 in umbilical cord serum from the maternal major depressive disorder

Matsuo, S., Moriyama, Y., Ushida, T., Imai, K., Tano, S., Miki, R., Yoshida, K., Yokoi, A., Kajiyama, H., & Kotani, T. (2024) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.16096 · Cited by 5 · see citing works

Increased levels of APOA4 in cord blood in maternal major depressive disorderPreprint

Matsuo, S., Moriyama, Y., Ushida, T., Imai, K., Tano, S., Miki, R., Yoshida, K., Yokoi, A., Kajiyama, H., & Kotani, T. (2023) · Research Square · doi:10.21203/rs.3.rs-3262467/v1 · Cited by 2 · see citing works

Comorbidity risk characteristics of rheumatoid arthritis in the context of depression-associated lipid metabolism

Liu, J., Xiang, C., Zhou, Q., Ding, Z., Wang, J., & Li, A. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1806730 · Cited by 1 · see citing works

Identification of significant biomarkers for predicting the risk of bipolar disorder with arteriosclerosis based on integrative bioinformatics and machine learning

Zheng, X., Zhang, X., Zhang, Y., Chen, C., & Ji, E. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1392437 · Cited by 1 · see citing works

Research on the mechanism of action of the Li Qi Dao Tan Decoction in the treatment of schizophrenia based on network pharmacology and molecular docking

Wang, S., Guo, F., Zhao, C., Shi, G., Liu, J., & Yang, S. (2025) · Medicine · doi:10.1097/md.0000000000043462

High-density lipoprotein (HDL) in older patients with schizophrenia: implications for clinical and cognitive outcomes

Chen, S., Liang, J., Li, C., Lin, C., Li, W., He, Z., Fan, F., & Zhang, S. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-07842-3

Platelet activation is associated with hypoadiponectinemia and carotid atherosclerosis

庄司, 拓. (2006)

Lysophospholipid-enriched HDL suppresses platelet activation

Ćurčić, S. (2017) · Intrinsic Activity · doi:10.25006/ia.5.s1-a2.2

Effects of Nutrients on Platelet Function: A Modifiable Link between Metabolic Syndrome and Neurodegeneration?

Arnoldussen, I. A. C., & Witkamp, R. F. (2021) · Biomolecules · doi:10.3390/biom11101455 · Cited by 12 · see citing works

Fenofibrate attenuates hyperhomocysteinemia-potentiated thrombosis by restoring platelet fatty acid β-oxidation

Han, L., Du, X., Yan, Y., Zhang, L., Feng, J., Wang, X., & Zhang, X. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104250

Critical role of peroxisome proliferator-activated receptor α in promoting platelet hyperreactivity and thrombosis under hyperlipidemia

Li, L., Zhou, J., Wang, S., Jiang, L., Chen, X., Zhou, Y., Li, J., Shi, J., Liu, P., Shu, Z., et al. (2021) · Haematologica · doi:10.3324/haematol.2021.279770 · Cited by 36 · see citing works