Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Bolstad, B. M., Irizarry, R. A., Åstrand, M., & Speed, T. P. (2003) · Bioinformatics · doi:10.1093/bioinformatics/19.2.185 · Cited by 8,185 · see citing works

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Mikkelsen, T. S., Ku, M., Jaffe, D. B., Issac, B., Lieberman, E., Giannoukos, G., Alvarez, P., Brockman, W., Kim, T.-K., Koche, R. P., et al. (2007) · Nature · doi:10.1038/nature06008 · Cited by 4,129 · see citing works

A gene atlas of the mouse and human protein-encoding transcriptomes

Su, A. I., Wiltshire, T., Batalov, S., Lapp, H., Ching, K. A., Block, D., Zhang, J., Soden, R., Hayakawa, M., Kreiman, G., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400782101 · Cited by 3,475 · see citing works

AMPA Receptor Trafficking and Synaptic Plasticity

Malinow, R., & Malenka, R. C. (2002) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.25.112701.142758 · Cited by 2,588 · see citing works

Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors

Lois, C., Hong, E. J., Pease, S., Brown, E. J., & Baltimore, D. (2002) · Science · doi:10.1126/science.1067081 · Cited by 1,974 · see citing works

Enriched environments, experience-dependent plasticity and disorders of the nervous system

Nithianantharajah, J., & Hannan, A. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1970 · Cited by 1,771 · see citing works

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

Sandberg, R., Neilson, J. R., Sarma, A., Sharp, P. A., & Burge, C. B. (2008) · Science · doi:10.1126/science.1155390 · Cited by 1,349 · see citing works

Kinesin Transports RNA

Kanai, Y., Dohmae, N., & Hirokawa, N. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.022 · Cited by 1,109 · see citing works

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

McKinsey, T. A., Zhang, C., Lu, J., & Olson, E. N. (2000) · Nature · doi:10.1038/35040593 · Cited by 1,051 · see citing works

A large-scale analysis of mRNA polyadenylation of human and mouse genes

Tian, B. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki158 · Cited by 944 · see citing works

A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories

Jones, M. W., Errington, M. L., French, P. J., Fine, A., Bliss, T., Garel, S., Charnay, P., Bozon, B., Laroche, S., & Davis, S. (2001) · Nature Neuroscience · doi:10.1038/85138 · Cited by 899 · see citing works

Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation

Zhou, Z., Hong, E. J., Cohen, S., Zhao, W.-N., Ho, H.-Y. H., Schmidt, L., Chen, W. G., Lin, Y., Savner, E., Griffith, E. C., et al. (2006) · Neuron · doi:10.1016/j.neuron.2006.09.037 · Cited by 877 · see citing works

MEF2: a central regulator of diverse developmental programs

Potthoff, M. J., & Olson, E. N. (2007) · Development · doi:10.1242/dev.008367 · Cited by 834 · see citing works

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

Flavell, S. W., & Greenberg, M. E. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125631 · Cited by 832 · see citing works

Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

Xia, Z., Dudek, H., Miranti, C. K., & Greenberg, M. E. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-17-05425.1996 · Cited by 794 · see citing works

Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

Chowdhury, S., Shepherd, J. D., Okuno, H., Lyford, G., Petralia, R. S., Plath, N., Kuhl, D., Huganir, R. L., & Worley, P. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.08.033 · Cited by 792 · see citing works

Identifying autism loci and genes by tracing recent shared ancestry

Morrow, E. M., Yoo, S.-Y., Flavell, S. W., Kim, T.-K., Lin, Y., Hill, R. S., Mukaddes, N. M., Balkhy, S., Gascon, G., Hashmi, A., et al. (2008) · Science · doi:10.1126/science.1157657 · Cited by 737 · see citing works

Defining the CREB Regulon

Impey, S., McCorkle, S., Cha‐Molstad, H., Dwyer, J. M., Yochum, G. S., Boss, J. M., McWeeney, S. K., Dunn, J. J., Mandel, G., & Goodman, R. H. (2004) · Cell · doi:10.1016/j.cell.2004.10.032 · Cited by 695 · see citing works

Activity-dependent regulation of inhibitory synapse development by Npas4

Lin, Y., Bloodgood, B. L., Hauser, J. L., Lapan, A. D., Koon, A. C., Kim, T.-K., Hu, L. S., Malik, A. N., & Greenberg, M. E. (2008) · Nature · doi:10.1038/nature07319 · Cited by 639 · see citing works

Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli

Renthal, W., Maze, I., Krishnan, V., Covington, H. E., Xiao, G., Kumar, A., Russo, S. J., Graham, A., Tsankova, N., Kippin, T. E., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.09.032 · Cited by 599 · see citing works

Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture.

Barco, A., Alarcon, J. M., & Kandel, E. (2002) · Cell · doi:10.1016/s0092-8674(02)00657-8 · Cited by 595 · see citing works

Activity-Dependent Regulation of MEF2 Transcription Factors Suppresses Excitatory Synapse Number

Flavell, S. W., Cowan, C. W., Kim, T.-K., Greer, P. L., Lin, Y., Paradis, S., Griffith, E. C., Hu, L. S., Chen, C., & Greenberg, M. E. (2006) · Science · doi:10.1126/science.1122511 · Cited by 573 · see citing works

Weeder Web: discovery of transcription factor binding sites in a set of sequences from co-regulated genes

Pavesi, G., Mereghetti, P., Mauri, G., & Pesole, G. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh465 · Cited by 491 · see citing works

A Calcium-Regulated MEF2 Sumoylation Switch Controls Postsynaptic Differentiation

Shalizi, A., Gaudilliere, B. L., Yuan, Z., Stegmüller, J., Shirogane, T., Ge, Q., Tan, Y. L., Schulman, B. A., Harper, J. W., & Bonni, A. (2006) · Science · doi:10.1126/science.1122513 · Cited by 456 · see citing works

X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment

Dibbens, L. M., Tarpey, P. S., Hynes, K., Bayly, M. A., Scheffer, I. E., Smith, R., Bomar, J. M., Sutton, E., Vandeleur, L., Shoubridge, C., et al. (2008) · Nature Genetics · doi:10.1038/ng.149 · Cited by 450 · see citing works

Neural activity and the dynamics of central nervous system development

Hua, J. Y., & Smith, S. J. (2004) · Nature Neuroscience · doi:10.1038/nn1218 · Cited by 450 · see citing works

Developmental Remodeling of the Retinogeniculate Synapse

Chen, C., & Regehr, W. G. (2000) · Neuron · doi:10.1016/s0896-6273(00)00166-5 · Cited by 439 · see citing works

Epilepsy-Related Ligand/Receptor Complex LGI1 and ADAM22 Regulate Synaptic Transmission

Fukata, Y., Adesnik, H., Iwanaga, T., Bredt, D. S., Nicoll, R. A., & Fukata, M. (2006) · Science · doi:10.1126/science.1129947 · Cited by 411 · see citing works

Impaired Long-Term Memory and NR2A-Type NMDA Receptor-Dependent Synaptic Plasticity in Mice Lacking c-Fos in the CNS

Fleischmann, A., Hvalby, Ø., Jensen, V., Strekalova, T. V., Zacher, C., Layer, L. E., Kvello, A., Reschke, M., Spanagel, R., Sprengel, R., et al. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-27-09116.2003 · Cited by 382 · see citing works

Brain-derived neurotrophic factor mediates the activity-dependent regulation of inhibition in neocortical cultures

Rutherford, L. C., DeWan, A., Lauer, H. M., & Turrigiano, G. G. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-12-04527.1997 · Cited by 381 · see citing works

MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function

Barbosa, A. C., Kim, M.-S., Ertunc, M., Adachi, M., Nelson, E. D., McAnally, J., Richardson, J. A., Kavalali, E. T., Monteggia, L. M., Bassel-Duby, R., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802679105 · Cited by 303 · see citing works

Inhibition of Dendritic Spine Morphogenesis and Synaptic Transmission by Activity-Inducible Protein Homer1a

Sala, C., Futai, K., Yamamoto, K., Worley, P. F., Hayashi, Y., & Sheng, M. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06327.2003 · Cited by 288 · see citing works

Fos B mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine’s psychomotor and rewarding effects

Hiroi, N., Brown, J. R., Haile, C. N., Ye, H., Greenberg, M. E., & Nestler, E. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10397 · Cited by 285 · see citing works

Dendrite Development Regulated by CREST, a Calcium-Regulated Transcriptional Activator

Aizawa, H., Hu, S., Bobb, K., Balakrishnan, K., Ince-Dunn, G., Gurevich, I., Cowan, M., & Ghosh, A. (2004) · Science · doi:10.1126/science.1089845 · Cited by 282 · see citing works

Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity

Pulipparacharuvil, S., Renthal, W., Hale, C. F., Taniguchi, M., Xiao, G., Kumar, A., Russo, S. J., Sikder, D., Dewey, C. M., Davis, M. M., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.020 · Cited by 281 · see citing works

Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites

Raab-Graham, K. F., Haddick, P. C. G., Jan, Y. N., & Jan, L. Y. (2006) · Science · doi:10.1126/science.1131693 · Cited by 267 · see citing works

A CaMKII-NeuroD Signaling Pathway Specifies Dendritic Morphogenesis

Gaudilliere, B. L., Konishi, Y., de la Iglesia, N., Yao, G.-L., & Bonni, A. (2004) · Neuron · doi:10.1016/s0896-6273(03)00841-9 · Cited by 248 · see citing works

Integration of calcineurin and MEF2 signals by the coactivator p300 during T‐cell apoptosis

Youn, H., Chatila, T. A., & Liu, J. O. (2000) · The EMBO Journal · doi:10.1093/emboj/19.16.4323 · Cited by 223 · see citing works

SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability

Ramanan, N., Shen, Y., Sarsfield, S., Lemberger, T., Schütz, G., Linden, D. J., & Ginty, D. D. (2005) · Nature Neuroscience · doi:10.1038/nn1462 · Cited by 218 · see citing works

A Role in Learning for SRF: Deletion in the Adult Forebrain Disrupts LTD and the Formation of an Immediate Memory of a Novel Context

Etkin, A., Alarcón, J. M., Weisberg, S. P., Touzani, K., Huang, Y. Y., Nordheim, A., & Kandel, E. R. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.013 · Cited by 218 · see citing works

Localized Synaptic Potentiation by BDNF Requires Local Protein Synthesis in the Developing Axon

Zhang, X.-H., & Poo, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)01023-1 · Cited by 209 · see citing works

Rap2-JNK Removes Synaptic AMPA Receptors during Depotentiation

Zhu, Y., Pak, D. T. S., Qin, Y., McCormack, S. G., Kim, M. J., Baumgart, J. P., Velamoor, V., Auberson, Y. P., Osten, P., Aelst, L. V., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.037 · Cited by 204 · see citing works

The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions

Simon, D. J., Madison, J. M., Conery, A. L., et al. (2008) · Cell · doi:10.1016/j.cell.2008.04.035 · Cited by 203 · see citing works

Epidermal Growth Factor Receptor Activation: An Upstream Signal for Transition of Quiescent Astrocytes into Reactive Astrocytes after Neural Injury

Liu, B., Chen, H., Johns, T. G., & Neufeld, A. H. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1004-06.2006 · Cited by 202 · see citing works

Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin‐deficient mice

Papadopoulos, T. G., Körte, M., Eulenburg, V., Kubota, H., Retiounskaia, M., Harvey, R. J., Harvey, K., O’Sullivan, G. A., Laube, B., Hülsmann, S., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601819 · Cited by 195 · see citing works

Activity-Induced Protocadherin Arcadlin Regulates Dendritic Spine Number by Triggering N-Cadherin Endocytosis via TAO2β and p38 MAP Kinases

Yasuda, S., Tanaka, H., Sugiura, H., Okamura, K., Sakaguchi, T., Tran, U., Takemiya, T., Mizoguchi, A., Yagita, Y., Sakurai, T., et al. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.020 · Cited by 193 · see citing works

Pause Sites Promote Transcriptional Termination of Mammalian RNA Polymerase II

Gromak, N., West, S., & Proudfoot, N. J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.10.3986-3996.2006 · Cited by 181 · see citing works

Somatostatin Inhibits Excitatory Transmission at Rat Hippocampal Synapses via Presynaptic Receptors

Boehm, S., & Betz, H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04066.1997 · Cited by 163 · see citing works

Effects of visual experience on activity-dependent gene regulation in cortex

Majdan, M., & Shatz, C. J. (2006) · Nature Neuroscience · doi:10.1038/nn1674 · Cited by 158 · see citing works

Complex Formation between the Postsynaptic Scaffolding Protein Gephyrin, Profilin, and Mena: A Possible Link to the Microfilament System

Giesemann, T., Schwarz, G., Nawrotzki, R., Berhörster, K., Rothkegel, M., Schlüter, K., Schrader, N., Schindelin, H., Mendel, R., Kirsch, J., et al. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-23-08330.2003 · Cited by 131 · see citing works

Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory

Li, L., Yun, S. H., Keblesh, J., Trommer, B. L., Xiong, H., Radulovic, J., & Tourtellotte, W. G. (2007) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2007.02.004 · Cited by 124 · cited 2× · see citing works

Type 8 Adenylyl Cyclase Is Targeted to Excitatory Synapses and Required for Mossy Fiber Long-Term Potentiation

Wang, H., Pineda, V. V., Chan, G. C. K., Wong, S. T., Muglia, L. J., & Storm, D. R. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-30-09710.2003 · Cited by 120 · see citing works

Regulation of Thalamocortical Patterning and Synaptic Maturation by NeuroD2

Ince-Dunn, G., Hall, B. J., Hu, S., Ripley, B. A., Huganir, R. L., Olson, J. M., Tapscott, S. J., & Ghosh, A. (2006) · Neuron · doi:10.1016/j.neuron.2006.01.031 · Cited by 119 · see citing works

Functional Outcome of B Cell Activation by Chromatin Immune Complex Engagement of the B Cell Receptor and TLR9

Busconi, L., Bauer, J. W., Tumang, J. R., Laws, A., Mesires, K. P., Tabor, A. S., Lau, C. M., Corley, R. B., Rothstein, T. L., Lund, F. E., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.11.7397 · Cited by 59 · see citing works

Differential Effects of PACAP-38 on Synaptic Responses in Rat Hippocampal CA1 RegionPreprint

Roberto, M., Scuri, R., & Brunelli, M. (2001) · Learning & Memory · doi:10.1101/lm.40501 · Cited by 55 · see citing works

PC4 Coactivates MyoD by Relieving the Histone Deacetylase 4-Mediated Inhibition of Myocyte Enhancer Factor 2C

Micheli, L., Leonardi, L., Conti, F., Buanne, P., Canu, N., Caruso, M., & Tirone, F. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2242-2259.2005 · Cited by 34 · see citing works

Immunohistochemical localization of the voltage-gated potassium channel subunit Kv1.4 in the central nervous system of the adult rat

Luján, R., de Cabo, C., del Toro, E. D., Ballesta, J. J., Criado, M., & Juiz, J. M. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.07.006 · Cited by 30 · see citing works

Jumonji represses α-cardiac myosin heavy chain expression via inhibiting MEF2 activity

Kim, T.-G., Jung, J., Mysliwiec, M. R., Kang, S.-Y., & Lee, Y. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.01.154 · Cited by 28 · see citing works

Identification of Expression Patterns of IL-2-Responsive Genes in the Murine T Cell Line CTLL-2

Zhang, Z., Martino, A., & Faulon, J. (2007) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2006.0169 · Cited by 13 · see citing works

U1 snRNP regulates cancer cell migration and invasion in vitro

Oh, J.-M., Venters, C. C., Di, C., Pinto, A. M., Wan, L., Younis, I., Cai, Z., Arai, C., So, B. R., Duan, J., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13993-7 · Cited by 7,157 · see citing works

Widespread transcription at neuronal activity-regulated enhancers

Kim, T.-K., Hemberg, M., Gray, J. M., Costa, A. M., Bear, D. M., Wu, J., Harmin, D. A., Laptewicz, M., Barbara-Haley, K., Kuersten, S., et al. (2010) · Nature · doi:10.1038/nature09033 · Cited by 2,450 · see citing works

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

Mayr, C., & Bartel, D. P. (2009) · Cell · doi:10.1016/j.cell.2009.06.016 · Cited by 1,613 · see citing works

The oxytocin receptor: from intracellular signaling to behavior

Jurek, B., & Neumann, I. D. (2018) · Physiological Reviews · doi:10.1152/physrev.00031.2017 · Cited by 999 · see citing works

Activity-dependent neuronal signalling and autism spectrum disorder

Ebert, D. H., & Greenberg, M. E. (2013) · Nature · doi:10.1038/nature11860 · Cited by 666 · see citing works

Regulation of cytoplasmic mRNA decay

Schoenberg, D. R., & Maquat, L. E. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3160 · Cited by 656 · see citing works

The Angelman Syndrome Protein Ube3A Regulates Synapse Development by Ubiquitinating Arc

Greer, P. L., Hanayama, R., Bloodgood, B. L., Mardinly, A. R., Lipton, D. M., Flavell, S. W., Kim, T.-K., Griffith, E. C., Waldon, Z., Maehr, R., et al. (2010) · Cell · doi:10.1016/j.cell.2010.01.026 · Cited by 30 · see citing works

Regulation by 3′-Untranslated Regions

Mayr, C. (2017) · Annual Review of Genetics · doi:10.1146/annurev-genet-120116-024704 · Cited by 588 · see citing works

From neural development to cognition: unexpected roles for chromatin

Ronan, J. L., Wu, W., & Crabtree, G. R. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3413 · Cited by 544 · see citing works

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

Estes, M. L., & McAllister, A. K. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3978 · Cited by 514 · see citing works

Neuronal Activity-Regulated Gene Transcription in Synapse Development and Cognitive Function

West, A. E., & Greenberg, M. E. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005744 · Cited by 532 · see citing works

What Are 3′ UTRs Doing?

Mayr, C. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a034728 · Cited by 519 · see citing works

Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs

Spiegel, I., Mardinly, A. R., Gabel, H. W., Bazinet, J. E., Couch, C. H., Tzeng, C. P., Harmin, D. A., & Greenberg, M. E. (2014) · Cell · doi:10.1016/j.cell.2014.03.058 · Cited by 416 · see citing works

Genome-wide meta-analysis identifies new susceptibility loci for migraine

North American Brain Expression Consortium, Anttila, V., UK Brain Expression Consortium, the International Headache Genetics Consortium, Winsvold, B. S., Gormley, P., Kurth, T., Bettella, F., McMahon, G., Kallela, M., et al. (2013) · Nature Genetics · doi:10.1038/ng.2676 · Cited by 410 · see citing works

Alternative 3′ UTRs modify the localization, regulatory potential, stability, and plasticity of mRNAs in neuronal compartments

Tushev, G., Glock, C., Heumüller, M., Biever, A., Jovanovic, M., & Schuman, E. M. (2018) · Neuron · doi:10.1016/j.neuron.2018.03.030 · Cited by 377 · see citing works

Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte Differentiation

Yu, Y., Chen, Y., Kim, B., Wang, H., Zhao, C., He, X., Liu, L., Liu, W., Wu, L. M. N., Mao, M., et al. (2013) · Cell · doi:10.1016/j.cell.2012.12.006 · Cited by 375 · see citing works

Translational control by changes in poly(A) tail length: recycling mRNAs

Weill, L., Belloc, E., Bava, F.-A., & Méndez, R. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2311 · Cited by 328 · see citing works

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

Tsai, N.-P., Wilkerson, J. R., Guo, W., Maksimova, M. A., DeMartino, G. N., Cowan, C. W., & Huber, K. M. (2012) · Cell · doi:10.1016/j.cell.2012.11.040 · Cited by 316 · see citing works

Tau Activation of Microglial cGAS–IFN Reduces MEF2C‐mediated Cognitive Resilience

Udeochu, J. C., Amin, S., Huang, Y., Fan, L., Torres, E. R. S., Carling, G. K., Liu, B., McGurran, H., Coronas-Samano, G., Kauwe, G., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01315-6 · Cited by 289 · see citing works

HDAC4 Governs a Transcriptional Program Essential for Synaptic Plasticity and Memory

Sando, R., Gounko, N., Pieraut, S., Liao, L., Yates, J., & Maximov, A. (2012) · Cell · doi:10.1016/j.cell.2012.09.037 · Cited by 274 · see citing works

Stimulus-specific combinatorial functionality of neuronal c-fos enhancers

Joo, J.-Y., Schaukowitch, K., Farbiak, L., Kilaru, G., & Kim, T.-K. (2016) · Nature Neuroscience · doi:10.1038/nn.4170 · Cited by 271 · see citing works

Reprogramming of 3′ Untranslated Regions of mRNAs by Alternative Polyadenylation in Generation of Pluripotent Stem Cells from Different Cell Types

Ji, Z., & Tian, B. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008419 · Cited by 264 · see citing works

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

Liu, X., Somel, M., Tang, L., Yan, Z., Jiang, X., Guo, S., Yuan, Y., He, L., Oleksiak, A., Zhang, Y., et al. (2012) · Genome Research · doi:10.1101/gr.127324.111 · Cited by 251 · see citing works

The end of the message: multiple protein–RNA interactions define the mRNA polyadenylation site

Shi, Y., & Manley, J. L. (2015) · Genes & Development · doi:10.1101/gad.261974.115 · Cited by 249 · see citing works

Autism genetics: searching for specificity and convergence

Berg, J. M., & Geschwind, D. H. (2012) · Genome Biology · doi:10.1186/gb-2012-13-7-247 · Cited by 192 · see citing works

Single-Cell RNA-Seq of Mouse Olfactory Bulb Reveals Cellular Heterogeneity and Activity-Dependent Molecular Census of Adult-Born Neurons

Tepe, B., Hill, M. C., Pekarek, B. T., Hunt, P. J., Martin, T. J., Martin, J. F., & Arenkiel, B. R. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.11.034 · Cited by 183 · see citing works

LRP8-Reelin-regulated neuronal enhancer signature underlying learning and memory formation

Telese, F., Ma, Q., Perez, P. M., Notani, D., Oh, S., Li, W., Comoletti, D., Ohgi, K. A., Taylor, H., & Rosenfeld, M. G. (2015) · Neuron · doi:10.1016/j.neuron.2015.03.033 · Cited by 166 · see citing works

Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2

Pfeiffer, B. E., Zang, T., Wilkerson, J. R., Taniguchi, M., Maksimova, M. A., Smith, L. N., Cowan, C. W., & Huber, K. M. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.017 · Cited by 153 · see citing works

Pre‐mRNA 3′‐end processing complex assembly and function

Chan, S., Choi, E., & Shi, Y. (2011) · WIREs RNA · doi:10.1002/wrna.54 · Cited by 147 · see citing works

Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism

Chahrour, M. H., Yu, T. W., Lim, E. T., Ataman, B., Coulter, M. E., Hill, R. S., Stevens, C. R., Schubert, C. R., ARRA Autism Sequencing Collaboration, Greenberg, M. E., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002635 · Cited by 125 · see citing works

Alternative pre-mRNA splicing in neurons: growing up and extending its reach

Zheng, S., & Black, D. L. (2013) · Trends in Genetics · doi:10.1016/j.tig.2013.04.003 · Cited by 115 · see citing works

Alternative polyadenylation diversifies post‐transcriptional regulation by selective RNA–protein interactions

Gupta, I., Clauder‐Münster, S., Klaus, B., Järvelin, A. I., Aiyar, R. S., Benes, V., Wilkening, S., Huber, W., Pelechano, V., & Steinmetz, L. M. (2014) · Molecular Systems Biology · doi:10.1002/msb.135068 · Cited by 95 · see citing works

Emerging roles for MEF2 in brain development and mental disorders

Assali, A., Harrington, A. J., & Cowan, C. W. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2019.04.008 · Cited by 92 · see citing works

An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior

Jung, Y., Hsieh, L. S., Lee, A. M., Zhou, Z., Coman, D., Heath, C. J., Hyder, F., Mineur, Y. S., Yuan, Q., Goldman, D., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4315 · Cited by 90 · see citing works

The why and how of sleep-dependent synaptic down-selection

Cirelli, C., & Tononi, G. (2022) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2021.02.007 · Cited by 74 · see citing works

A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex

Yang, S. W., Li, L., Connelly, J. P., Porter, S. N., Kodali, K., Gan, H., Park, J. M., Tacer, K. F., Tillman, H., Peng, J., et al. (2020) · Molecular Cell · doi:10.1016/j.molcel.2019.12.022 · Cited by 79 · see citing works

cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation

Hwang, H.-W., Saito, Y., Park, C. Y., Blachère, N. E., Tajima, Y., Fak, J. J., Zucker-Scharff, I., & Darnell, R. B. (2017) · Neuron · doi:10.1016/j.neuron.2017.08.024 · Cited by 74 · see citing works

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in <i>Drosophila melanogaster</i>

Liu, X., Freitas, J., Zheng, D., Oliveira, M. S., Hoque, M., Martins, T., Henriques, T., Tian, B., & Moreira, A. (2017) · RNA · doi:10.1261/rna.062661.117 · Cited by 67 · see citing works

The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia

Nehme, R., Pietiläinen, O., Artomov, M., Tegtmeyer, M., Valakh, V., Lehtonen, L., Bell, C., Singh, T., Trehan, A., Sherwood, J., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-31436-8 · Cited by 58 · see citing works

Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action

Lanz, T. A., Guilmette, E., Gosink, M. M., Fischer, J. E., Fitzgerald, L. W., Stephenson, D. T., & Pletcher, M. T. (2013) · Molecular Autism · doi:10.1186/2040-2392-4-45 · Cited by 52 · see citing works

Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling

Zhang, Z., Cao, M., Chang, C.-W., Wang, C., Shi, X., Zhan, X., Birnbaum, S. G., Bezprozvanny, I., Huber, K. M., & Wu, J. I. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.00534-15 · Cited by 48 · see citing works

The transcriptional elongation rate regulates alternative polyadenylation in yeast

Geisberg, J. V., Moqtaderi, Z., & Struhl, K. (2020) · eLife · doi:10.7554/elife.59810 · Cited by 45 · see citing works

MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors

Mahgoub, M., Adachi, M., Suzuki, K., Liu, X., Kavalali, E. T., Chahrour, M. H., & Monteggia, L. M. (2016) · Nature Neuroscience · doi:10.1038/nn.4395 · Cited by 40 · see citing works

Angelman syndrome: advancing the research frontier of neurodevelopmental disorders

Philpot, B. D., Thompson, C. E., Franco, L., & Williams, C. A. (2011) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-010-9066-z · Cited by 17 · see citing works

The ENCODE Project Decoded

Stailey, M. (2012) · Microreviews in Cell and Molecular Biology

PolyA_DB: a database for mammalian mRNA polyadenylation

Zhang, H. (2004) · Nucleic Acids Research · doi:10.1093/nar/gki055 · Cited by 132 · see citing works

Alternative polyadenylation of poly(A) binding protein nuclear 1 (PABPN1) mRNA

Hague‐Canto, L. K., Tian, B., & Lutz, C. S. (2009) · The FASEB Journal · doi:10.1096/fasebj.23.1_supplement.662.2

Plant cells do not properly recognize animal gene polyadenylation signals

Hunt, A. G., Chu, N. M., Odell, J. T., et al. (1987) · Plant Molecular Biology · doi:10.1007/bf00016431 · Cited by 73 · see citing works

The Study of OCDMA Encode/Decode Using Multilayer Films

Ze, G. (2001) · Beijing Youdian Xueyuan xuebao