Cited by 478Obsessive-Compulsive Spectrum DisordersNeurological disorders and treatmentsNeurotransmitter Receptor Influence on Behavior

Recent advances in Tourette syndrome research

Albin, Roger L., Mink, Jonathan W.·2006·Trends in Neurosciences

Abstract

Tourette syndrome (TS) is a developmentally regulated neurobehavioral disorder characterized by involuntary, stereotyped, repetitive movements. Recent anatomical and neuroimaging studies have provided evidence for abnormal basal ganglia and dopaminergic function in TS. Basic research on striatal inhibitory mechanisms and dopaminergic function complements the recent neuroimaging and anatomical data. Parallel studies of basal ganglia participation in the normal performance and learning of stereotyped repetitive behaviors or habits has provided additional insight. These lines of research have provided new pieces to the TS puzzle, and their increasing convergence is showing how those pieces can be put together.

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Crossref · 10.1016/j.tins.2006.01.001

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Authors
Albin, R. L., & Mink, J. W.
Affiliations
  • University of Michigan (US)
  • University of Rochester Medicine (US)
Corresponding author
Mink, Jonathan W.
Venue
Trends in Neurosciences
Publisher
Elsevier BV
Published
2006-03
Volume
29
Issue
3
Pages
175-182
ISSN
0166-2236 (ISSN-L)
OpenAlex
W2060469305
Cited by
478
References
112
Citations by year
2026: 16 · 2025: 13 · 2024: 14 · 2023: 13 · 2022: 20 · 2021: 20 · 2020: 37 · 2019: 19 · 2018: 19 · 2017: 26 · 2016: 24 · 2015: 33 · 2014: 29 · 2013: 31 · 2012: 27
FWCI
3.26
Type
journal article
Language
en
Open access
closed
Locations
  • Trends in Neurosciences (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Health Sciences › Medicine › Neurology › Neurological disorders and treatments
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
Tourette syndrome, basal ganglia, dopaminergic activity, habit, neurobehavioral disorders, neuroimaging
MeSH terms
Basal Ganglia, Dopamine, Tourette Syndrome, Humans, Magnetic Resonance Imaging, Organ Size, Research, Tics

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