Differential effects on cognitive functioning in 13- to 16-year-olds prenatally exposed to cigarettes and marihuana
Abstract
Cognitive performance was examined in 145 thirteen- to sixteen-year-old adolescents for whom prenatal exposure to marihuana and cigarettes had been ascertained. The subjects were from a low-risk, predominantly middle-class sample participating in an ongoing, longitudinal study. The assessment battery included tests of general intelligence, achievement, memory, and aspects of executive functioning (EF). Consistent with results obtained at earlier ages, the strongest relationship between prenatal maternal cigarette smoking and cognitive variables was seen with overall intelligence and aspects of auditory functioning whereas prenatal exposure to marihuana was negatively associated with tasks that required visual memory, analysis, and integration. The interpretation of the results is discussed in terms of the differential observations related to in utero exposure to cigarettes and marihuana and the nature of the cognitive variables associated with the two drugs.
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Central processing of auditory stimuli appears to be highly sensitive to disruption by gestational tobacco exposure.
“In particular, central processing of auditory stimuli appears to be highly sensitive to disruption by gestational tobacco exposure.”
From Impaired auditory discrimination learning following perinatal nicotine exposure or β2 nicotinic acetylcholine receptor subunit deletion (2012) · cites this paper as [17]
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- Authors
- Fried, P. A., Watkinson, B., & Gray, R.
- Affiliations
- Carleton University (CA)
- Corresponding author
- Fried, Peter A
- Venue
- Neurotoxicology and Teratology
- Publisher
- Elsevier BV
- Published
- 2003-07
- Volume
- 25
- Issue
- 4
- Pages
- 427-436
- ISSN
- 0892-0362 (ISSN-L)
- OpenAlex
- W1995015234
- Cited by
- 458
- References
- 84
- Citations by year
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- FWCI
- 22.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurotoxicology and Teratology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Drug Abuse
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- prenatal drug exposure, prenatal cannabis exposure, cognitive function, executive function, intelligence, WISC-III, children, dose-response relationship, impulse control, hypothesis testing, passive smoking, prefrontal cortex
- MeSH terms
- Adolescent, Auditory Perception, Cannabis, Cognition, Female, Humans, Intelligence, Intelligence Tests, Male, Memory, Neuropsychological Tests, Pregnancy, Prenatal Exposure Delayed Effects, Prospective Studies, Smoking
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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