Towards a functional neuroanatomy of self-processing: effects of faces and words
Abstract
We studied the neural correlates of self vs. non-self judgements using functional magnetic resonance imaging (fMRI). Individually tailored faces and personality trait words were used as stimuli in three experiments (exp.). In the first two experiments, brain activation was measured while subjects viewed morphed versions of either their own (self face exp.) or their partner's face (partner's face exp.), alternating in blocks with presentation of an unknown face. In the self face exp. right limbic areas (hippocampal formation, insula, anterior cingulate), the right middle temporal lobe, left inferior parietal and left prefrontal regions showed signal changes. In the partner's face exp., only the right insula was activated. In the third exp., subjects made decisions about psychological trait adjectives previously categorized as describing their own attributes. Activation was present in the precuneus, the left parietal lobe, left insula/inferior frontal gyrus and the left anterior cingulate. A reaction time advantage was present when subjects responded to self-relevant words. The main area with signal changes during self-reference processing, regardless of the type of stimulus, was the left fusiform gyrus. The self-relevant stimuli engaged to a differential extent long term and working memory, semantic and emotional processes. We suggest that regions activated by these stimuli are engaged in self-processing.
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“…versus a third-person perspective, when participants attribute seen actions to self versus others, or judgment of personality traits pertaining to self versus others (David et al., 2006; Farrer & Frith, 2002; Kircher et al., 2000; Lambrey et al., 2012; Ruby & Decety, 2001; Vogeley et al., 2004).”
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- Authors
- Kircher, T. T. J., Senior, C., Phillips, M. L., Benson, P. J., Bullmore, E. T., Brammer, M., Simmons, A., Williams, S. C. R., Bartels, M., & David, A. S.
- Affiliations
- University of Tübingen (DE)
- University of Oxford (GB)
- King's College London (GB)
- Corresponding author
- Kircher, Tilo T.J
- ORCID
- Venue
- Cognitive Brain Research
- Publisher
- Elsevier BV
- Published
- 2000-09
- Volume
- 10
- Issue
- 1-2
- Pages
- 133-144
- ISSN
- 0926-6410 (ISSN-L)
- OpenAlex
- W1998939912
- Cited by
- 403
- References
- 70
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 13 · 2023: 26 · 2022: 11 · 2021: 18 · 2020: 16 · 2019: 19 · 2018: 14 · 2017: 22 · 2016: 19 · 2015: 12 · 2014: 17 · 2013: 25 · 2012: 23
- FWCI
- 3.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cognitive Brain Research (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- self-processing, self-referential processing, self-face perception, face perception, self-relevance, fusiform gyrus, insula, anterior cingulate cortex, hippocampal formation, precuneus, limbic system, reaction time, working memory, semantic processing, emotional processing
- MeSH terms
- Adult, Behavior, Brain, Brain Mapping, Discrimination, Psychological, Ego, Face, Humans, Judgment, Language, Magnetic Resonance Imaging, Male, Pattern Recognition, Visual, Personality, Self Concept
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