Neural correlates of trauma-unrelated emotional processing in war veterans with PTSD
Open accessAbstract
Background: Post-traumatic stress disorder (PTSD) is thought to be characterized by general heightened amygdala activation. However, this hypothesis is mainly based on specific studies presenting fear or trauma-related stimuli, hence, a thorough investigation of trauma-unrelated emotional processing in PTSD is needed. Methods: In this study, 31 male medication-naive veterans with PTSD, 28 male control veterans (combat controls; CC) and 25 non-military men (healthy controls; HC) were included. Participants underwent functional MRI while trauma-unrelated neutral, negative and positive emotional pictures were presented. In addition to the group analyses, PTSD patients with and without major depressive disorder (MDD) were compared. Results: All groups showed an increased amygdala response to negative and positive contrasts, but amygdala activation did not differ between groups. However, a heightened dorsal anterior cingulate cortex (dACC) response for negative contrasts was observed in PTSD patients compared to HC. The medial superior frontal gyrus was deactivated in the negative contrast in HC, but not in veterans. PTSD+MDD patients showed decreased subgenual ACC (sgACC) activation to all pictures compared to PTSD–MDD. Conclusion: Our findings do not support the hypothesis that increased amygdala activation in PTSD generalizes to trauma-unrelated emotional processing. Instead, the increased dACC response found in PTSD patients implicates an attentional bias that extends to trauma-unrelated negative stimuli. Only HC showed decreased medial superior frontal gyrus activation. Finally, decreased sgACC activation was related to MDD status within the PTSD group.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Amygdala hyperactivity in PTSD may only become apparent during presentation of trauma-related stimuli and not during processing of non-trauma-related stimuli.
“Alternatively, amygdala hyperactivity in PTSD may only become apparent during presentation of trauma-related stimuli and not during processing of non-trauma-related stimuli (van Rooij et al, 2014), such as the emotional faces used in the present study.”
From Intranasal oxytocin administration dampens amygdala reactivity towards emotional faces in male and female PTSD patients (2016) · cites this paper as van Rooij et al, 2014
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900 · see citing works
Diagnostic and Statistical Manual of Mental Disorders(DSM)
Leong, F. T. L. (2008) · Sage eBooks · doi:10.4135/9781412963978.n182 · Cited by 10,858 · see citing works
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444 · see citing works
A cognitive model of posttraumatic stress disorder
Ehlers, A., & Clark, D. M. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(99)00123-0 · Cited by 6,147 · see citing works
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059 · see citing works
Functional neuroanatomy of emotion: A meta-analysis of emotion activation studies in PET and fMRI
Phan, K. L., Wager, T., Taylor, S. F., & Liberzon, I. (2002) · NeuroImage · doi:10.1006/nimg.2002.1087 · Cited by 3,502 · see citing works
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · cited 3× · see citing works
“Unlike theamygdala response which is implicated in various psychiatric disorders, the dACC has specifically been associated with PTSD (Etkin & Wager, 2007); our findings highlight the importance of the (d)ACC in PTSD. Increased activation in the left compared to the right hippocampus and insula was…”
BackgroundPsychophysiological and Modulatory Interactions in Neuroimaging
Friston, K. J., Buechel, C., Fink, G. R., Morris, J., Rolls, E., & Dolan, R. J. (1997) · NeuroImage · doi:10.1006/nimg.1997.0291 · Cited by 3,097 · see citing works
Emotional processing in anterior cingulate and medial prefrontal cortex
Etkin, A., Egner, T., & Kalisch, R. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.11.004 · Cited by 3,059 · cited 3× · see citing works
“The dACC is thought to play a role in the regulation of both cognitive and emotional processing (Phan et al. 2002; Etkin et al. 2011).”
BackgroundInternational Affective Picture System (IAPS) : Technical Manual and Affective Ratings
Lang, P. J. (1995) · Medical Entomology and Zoology · Cited by 2,870 · see citing works
Subgenual prefrontal cortex abnormalities in mood disorders
Drevets, W. C., Price, J. L., Simpson, J. R., Todd, R. D., Reich, T., Vannier, M., & Raichle, M. E. (1997) · Nature · doi:10.1038/386824a0 · Cited by 2,693 · see citing works
Rethinking feelings: an fMRI study of the cognitive regulation of emotion
Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. E. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902760807212 · Cited by 2,520 · see citing works
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416 · see citing works
Trauma and Posttraumatic Stress Disorder in the Community: The 1996 Detroit Area Survey of Trauma
Breslau, N., Kessler, R. C., Chilcoat, H. D., Schultz, L. R., Davis, G. C., & Andreski, P. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.7.626 · Cited by 2,407 · see citing works
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173 · see citing works
Neurobiology of emotion perception II: implications for major psychiatric disorders
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00171-9 · Cited by 1,736 · see citing works
Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma
Gilbertson, M. W., Shenton, M. E., Ciszewski, A., Kasai, K., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2002) · Nature Neuroscience · doi:10.1038/nn958 · Cited by 1,635 · see citing works
Rauch, S. L., Shin, L. M., & Phelps, E. A. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.06.004 · Cited by 1,397 · see citing works
Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder
Milad, M. R., Pitman, R. K., Ellis, C. B., Gold, A. L., Shin, L. M., Lasko, N. B., Zeidan, M. A., Handwerger, K., Orr, S. P., & Rauch, S. L. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.06.026 · Cited by 1,339 · see citing works
Amygdala, medial prefrontal cortex, and hippocampal function in PTSD
SHIN, L. M., RAUCH, S. L., & PITMAN, R. K. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.007 · Cited by 1,203 · see citing works
A clinician rating scale for assessing current and lifetime PTSD. The CAPS-1
Blake, D. D., Weathers, F. W., Nagy, L., Kaloupek, D. G., Klauminzer, G. W., Charney, D. S., & Keane, T. M. (1990) · Behavior Therapy · Cited by 1,123 · see citing works
Rauch, S. L., Whalen, P. J., Shin, L. M., McInerney, S. C., Macklin, M. L., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00828-3 · Cited by 1,111 · see citing works
The Amygdala Response to Emotional Stimuli: A Comparison of Faces and Scenes
Hariri, A. R., Tessitore, A., Mattay, V. S., Fera, F., & Weinberger, D. R. (2002) · NeuroImage · doi:10.1006/nimg.2002.1179 · Cited by 984 · see citing works
Shin, L. M., Wright, C. I., Cannistraro, P. A., Wedig, M. M., McMullin, K., Martis, B., Macklin, M. L., Lasko, N. B., Cavanagh, S. R., Krangel, T. S., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.273 · Cited by 960 · see citing works
The International Standard Classification of Education 2011
Schneider, S. L. (2013) · Comparative social research · doi:10.1108/s0195-6310(2013)0000030017 · Cited by 898 · see citing works
A meta-analysis of structural brain abnormalities in PTSD
KARL, A., SCHAEFER, M., MALTA, L., DORFEL, D., ROHLEDER, N., & WERNER, A. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.03.004 · Cited by 881 · see citing works
Gitelman, D. R., Penny, W. D., Ashburner, J., & Friston, K. J. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00058-2 · Cited by 799 · see citing works
Shin, L. M., Orr, S. P., Carson, M. A., Rauch, S. L., Macklin, M. L., Lasko, N. B., Peters, P. M., Metzger, L. J., Dougherty, D. D., Cannistraro, P. A., et al. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.2.168 · Cited by 790 · see citing works
Beckmann, M., Johansen-Berg, H., & Rushworth, M. F. S. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3328-08.2009 · Cited by 789 · see citing works
Bremner, J. D., Vythilingam, M., Vermetten, E. H. G. J. M., Southwick, S. M., McGlashan, T. H., Nazeer, A., Khan, S., Vaccarino, V., Soufer, R., Garg, P. K., et al. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.5.924 · Cited by 721 · see citing works
Bremner, J. D., Staib, L. H., Kaloupek, D. G., Southwick, S. M., Soufer, R., & Charney, D. S. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00297-2 · Cited by 704 · see citing works
Bremner, J. D., Narayan, M., Staib, L. H., Southwick, S. M., McGlashan, T., & Charney, D. S. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.11.1787 · Cited by 701 · see citing works
Drevets, W. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00102-5 · Cited by 581 · see citing works
Patel, R., Spreng, R. N., Shin, L. M., & Girard, T. A. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.06.003 · Cited by 546 · see citing works
Lanius, R. A., Williamson, P. C., Densmore, M., Boksman, K., Gupta, M. A., Neufeld, R. W., Gati, J. S., & Menon, R. S. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1920 · Cited by 521 · see citing works
Visual Imagery and Perception in Posttraumatic Stress Disorder
Shin, L. M. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830150057010 · Cited by 446 · see citing works
Subjective rating of emotionally salient stimuli modulates neural activity
Taylor, S. F., Phan, K. L., Decker, L. R., & Liberzon, I. (2003) · NeuroImage · doi:10.1016/s1053-8119(02)00051-4 · Cited by 371 · see citing works
Recall of emotional states in posttraumatic stress disorder: an fMRI investigation
Lanius, R. A., Williamson, P. C., Hopper, J., Densmore, M., Boksman, K., Gupta, M. A., Neufeld, R. W. J., Gati, J. S., & Menon, R. S. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01466-x · Cited by 311 · see citing works
Stevens, J. S., Jovanovic, T., Fani, N., Ely, T. D., Glover, E. M., Bradley, B., & Ressler, K. J. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.05.031 · Cited by 293 · see citing works
Altered Processing of Contextual Information during Fear Extinction in PTSD: An fMRI Study
Rougemont-Bücking, A., Linnman, C., Zeffiro, T. A., Zeidan, M. A., Lebron-Milad, K., Rodriguez-Romaguera, J., Rauch, S. L., Pitman, R. K., & Milad, M. R. (2011) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00152.x · Cited by 292 · see citing works
Prevalence of posttraumatic stress disorder in Veterans Affairs primary care clinics
Magruder, K. M., Frueh, B. C., Knapp, R. G., Davis, L. L., Hamner, M. B., Martin, R. H., Gold, P. B., & Arana, G. W. (2005) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2004.11.001 · Cited by 268 · see citing works
Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery
Britton, J. C., Phan, K. L., Taylor, S. F., Fig, L. M., & Liberzon, I. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.12.025 · Cited by 265 · see citing works
Bryant, R. A., Kemp, A. H., Felmingham, K. L., Liddell, B. J., Olivieri, G., Peduto, A. J., Gordon, E., & Williams, L. M. (2007) · Human Brain Mapping · doi:10.1002/hbm.20415 · Cited by 251 · see citing works
Fonzo, G. A., Simmons, A. N., Thorp, S. R., Norman, S. B., Paulus, M. P., & Stein, M. B. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.04.028 · Cited by 235 · see citing works
Altered Pain Processing in Veterans With Posttraumatic Stress Disorder
Geuze, E., Westenberg, H. G. M., Jochims, A., de Kloet, C. S., Bohus, M., Vermetten, E. H. G. J. M., & Schmahl, C. G. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.1.76 · Cited by 213 · see citing works
Self-citationBryant, R. A., Felmingham, K. L., Kemp, A. H., Barton, M., Peduto, A. S., Rennie, C., Gordon, E., & Williams, L. M. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.021 · Cited by 211 · see citing works
Nagahama, Y., Okada, T., Katsumi, Y., Hayashi, T., Yamauchi, H., Sawamoto, N., Toma, K., Nakamura, K., Hanakawa, T., Konishi, J., et al. (1999) · NeuroImage · doi:10.1006/nimg.1999.0451 · Cited by 203 · see citing works
Allard, C. B. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1539 · Cited by 203 · see citing works
Sex Differences in the Responses of the Human Amygdala
Hamann, S. B. (2005) · The Neuroscientist · doi:10.1177/1073858404271981 · Cited by 201 · see citing works
Dougherty, D. D., Weiss, A. P., Cosgrove, G. R., Alpert, N. M., Cassem, E. H., Nierenberg, A. A., Price, B. H., Mayberg, H. S., Fischman, A. J., & Rauch, S. L. (2003) · Journal of Neurosurgery · doi:10.3171/jns.2003.99.6.1010 · Cited by 193 · see citing works
Perceived threat predicts the neural sequelae of combat stress
van Wingen, G. A., Geuze, E., Vermetten, E., & Fernández, G. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.132 · Cited by 173 · see citing works
Self-citationDeep brain stimulation for treatment-resistant depression
Holtzheimer, P. E., & Hamani, C. (2014) · doi:10.2217/ebo.13.577 · Cited by 172 · see citing works
Shin, L. M., Bush, G., Milad, M. R., Lasko, N. B., Brohawn, K. H., Hughes, K. C., Macklin, M. L., Gold, A. L., Karpf, R. D., Orr, S. P., et al. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.09121812 · Cited by 170 · see citing works
Corticolimbic Blood Flow During Nontraumatic Emotional Processing in Posttraumatic Stress Disorder
Phan, K. L., Britton, J. C., Taylor, S. F., Fig, L. M., & Liberzon, I. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.2.184 · Cited by 161 · see citing works
Attention and emotion: Does rating emotion alter neural responses to amusing and sad films?
Hutcherson, C. A., Goldin, P. R., Ochsner, K. N., Gabrieli, J. D., Barrett, L. F., & Gross, J. J. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.04.028 · Cited by 154 · see citing works
Neural correlates of attention bias to threat in post-traumatic stress disorder
Fani, N., Jovanovic, T., Ely, T. D., Bradley, B., Gutman, D., Tone, E. B., & Ressler, K. J. (2012) · Biological Psychology · doi:10.1016/j.biopsycho.2012.03.001 · Cited by 150 · see citing works
Herringa, R., Phillips, M., Almeida, J., Insana, S., & Germain, A. (2012) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2012.02.005 · Cited by 143 · see citing works
The Neural Correlates of Emotional Memory in Posttraumatic Stress Disorder
Brohawn, K. H., Offringa, R., Pfaff, D. L., Hughes, K. C., & Shin, L. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.07.018 · Cited by 127 · see citing works
Lanius, R. A., Frewen, P. A., Girotti, M., Neufeld, R. W. J., Stevens, T. K., & Densmore, M. (2007) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2006.11.006 · Cited by 126 · see citing works
Lindauer, R. J. L., Booij, J., Habraken, J. B. A., Uylings, H. B. M., Olff, M., Carlier, I. V. E., den Heeten, G. J., van Eck-Smit, B. L. F., & Gersons, B. P. R. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.08.003 · Cited by 119 · see citing works
Sakamoto, H., Fukuda, R., Okuaki, T., Rogers, M. A., Kasai, K., Machida, T., Shirouzu, I., Yamasue, H., Akiyama, T., & Kato, N. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.02.032 · Cited by 118 · see citing works
Thomaes, K., Dorrepaal, E., Draijer, N. P. J., de Ruiter, M. B., Elzinga, B. M., van Balkom, A. J., Smoor, P. L. M., Smit, J., & Veltman, D. J. (2009) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2008.03.003 · Cited by 116 · see citing works
St. Jacques, P. L., Botzung, A., Miles, A., & Rubin, D. C. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.10.011 · Cited by 112 · see citing works
Hippocampal function during associative learning in patients with posttraumatic stress disorder.
Werner, N. S., Meindl, T., Engel, R., Rosner, R., Riedel, M., Reiser, M., & Fast, K. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2008.03.011 · Cited by 108 · see citing works
Thomaes, K., Dorrepaal, E., Draijer, N., de Ruiter, M. B., Elzinga, B. M., Sjoerds, Z., van Balkom, A. J., Smit, J. H., & Veltman, D. J. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr084 · Cited by 103 · see citing works
Brunetti, M., Sepede, G., Mingoia, G., Catani, C., Ferretti, A., Merla, A., Del Gratta, C., Romani, G. L., & Babiloni, C. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.04.024 · Cited by 101 · see citing works
Whalley, M. G., Rugg, M. D., Smith, A. P. R., Dolan, R. J., & Brewin, C. R. (2008) · Brain and Cognition · doi:10.1016/j.bandc.2008.05.008 · Cited by 97 · see citing works
Selective activation of the superior frontal gyrus in task-switching: An event-related fNIRS study
Cutini, S., Scatturin, P., Menon, E., Bisiacchi, P. S., Gamberini, L., Zorzi, M., & Dell’Acqua, R. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.05.013 · Cited by 95 · see citing works
Aupperle, R. L., Allard, C. B., Simmons, A. N., Flagan, T., Thorp, S. R., Norman, S. B., Paulus, M. P., & Stein, M. B. (2013) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2013.05.001 · Cited by 93 · cited 2× · see citing works
“Other studies showed reduced bilateral insula activation to anticipation of negative or positive pictures after treatment (Aupperle et al. 2013), and bilateral increased insula activation to pain stimuli (Geuze et al.”
BackgroundDevelopment and Psychometric Characteristics of the Dissociation Tension Scale
Stiglmayr, C., Schimke, P., Wagner, T., Braakmann, D., Schweiger, U., Sipos, V., Fydrich, T., Schmahl, C., Ebner-Priemer, U., Kleindienst, N., et al. (2010) · Journal of Personality Assessment · doi:10.1080/00223891003670232 · Cited by 80 · cited 1× · see citing works
“After the MRI scan, the dissociative state symptom scale – short form (DSS; Stiglmayr et al. 2010) was used to examine the presence of dissociative symptoms during the MRI scan.”
MethodFelmingham, K. L., Williams, L. M., Kemp, A. H., Rennie, C., Gordon, E., & Bryant, R. A. (2009) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2008.12.005 · Cited by 77 · see citing works
Gold, A. L., Shin, L. M., Orr, S. P., Carson, M. A., Rauch, S. L., Macklin, M. L., Lasko, N. B., Metzger, L. J., Dougherty, D. D., Alpert, N. M., et al. (2011) · Psychological Medicine · doi:10.1017/s0033291711000730 · Cited by 72 · see citing works
Jatzko, A., Schmitt, A., Demirakça, T., Weimer, E., & Braus, D. F. (2005) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-005-0617-3 · Cited by 63 · see citing works
van Buuren, M., Vink, M., Rapcencu, A. E., & Kahn, R. S. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.03.011 · Cited by 62 · see citing works
Self-citationSimmons, A. N., Norman, S. B., Spadoni, A. D., & Strigo, I. A. (2013) · Psychotherapy and Psychosomatics · doi:10.1159/000348867 · Cited by 60 · see citing works
Influence of comorbid depression on fear in posttraumatic stress disorder: an fMRI study
Kemp, A. H., Felmingham, K., Das, P., Hughes, G., Peduto, A. S., Bryant, R. A., & Williams, L. M. (2007) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2007.01.010 · Cited by 57 · see citing works
Dickie, E. W., Brunet, A., Akerib, V., & Armony, J. L. (2012) · Psychological Medicine · doi:10.1017/s0033291712001328 · Cited by 52 · see citing works
Altered amygdala activation during face processing in Iraqi and Afghanistani war veterans
Simmons, A. N., Matthews, S. C., Strigo, I. A., Baker, D. G., Donovan, H., Motezadi, A., Stein, M. B., & Paulus, M. P. (2011) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-1-6 · Cited by 50 · see citing works
Further characterisation of the functional neuroanatomy associated with prosodic emotion decoding
Mitchell, R. L. C. (2012) · Cortex · doi:10.1016/j.cortex.2012.07.010 · Cited by 10 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Reward functioning in PTSD: a systematic review exploring the mechanisms underlying anhedonia
Nawijn, L., van Zuiden, M., Frijling, J. L., Koch, S. B. J., Veltman, D. J., & Olff, M. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.01.019 · Cited by 250 · see citing works
Stark, E. A., Parsons, C. E., Van Hartevelt, T. J., Charquero-Ballester, M., McManners, H., Ehlers, A., Stein, A., & Kringelbach, M. L. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.07.007 · Cited by 152 · see citing works
Role of social cognition in post-traumatic stress disorder: a review and meta-analysis.
Stevens, J. S., & Jovanovic, T. (2019) · Genes, Brain and Behavior · doi:10.1111/gbb.12518 · Cited by 139 · see citing works
van Rooij, S. J. H., Kennis, M., Vink, M., & Geuze, E. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.257 · Cited by 122 · see citing works
Self-citationSchulze, L., Schulze, A., Renneberg, B., Schmahl, C., & Niedtfeld, I. (2019) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2018.11.004 · Cited by 102 · see citing works
Koch, S. B., van Zuiden, M., Nawijn, L., Frijling, J. L., Veltman, D. J., & Olff, M. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.299 · Cited by 98 · see citing works
Lieberman, L., Gorka, S. M., Funkhouser, C. J., Shankman, S. A., & Phan, K. L. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.04.002 · Cited by 30 · see citing works
- Authors
- van Rooij, S. J. H., Rademaker, A. R., Kennis, M., Vink, M., Kahn, R. S., & Geuze, E.
- Affiliations
- Ministry of Defence (NL)
- University Medical Center Utrecht (NL)
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2014-07-18
- Volume
- 45
- Issue
- 3
- Pages
- 575-587
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2134464723
- Cited by
- 36
- References
- 79
- Citations by year
- 2025: 1 · 2024: 6 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 3 · 2017: 4 · 2016: 2 · 2015: 4
- FWCI
- 3.93
- Type
- journal article
- Language
- en
- Open access
- green
- dspace.library.uu.nl
- Licence
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Funders
- Ministerie van Defensie
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- post-traumatic stress disorder, war veterans, amygdala activation, dorsal anterior cingulate cortex, subgenual anterior cingulate cortex, medial superior frontal gyrus, major depressive disorder, attentional bias, emotional picture processing, combat exposure
- MeSH terms
- War Exposure, Adult, Amygdala, Major Depressive Disorder, Emotions, Gyrus Cinguli, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Stress Disorders, Post-Traumatic, Veterans, Case-Control Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
