Nanomaterials for Nanotheranostics: Tuning Their Properties According to Disease Needs

Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases

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Atherosclerosis

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The blood-brain barrier

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Fundamentals of Cancer Metabolism

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Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

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Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

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Functional Nanomaterials for Phototherapies of Cancer

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Biomedical photoacoustic imaging

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Noninvasive detection of clinically occult lymph-node metastases in prostate cancer

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Nano-graphene in biomedicine: theranostic applications

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Melanoma

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Nanoparticle uptake: The phagocyte problem

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A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

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Nanoparticles in the clinic

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Nanomaterials for Theranostics: Recent Advances and Future Challenges

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Colloidal Gold: A Novel Nanoparticle Vector for Tumor Directed Drug Delivery

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Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

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Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

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Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

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Nanomaterials for In Vivo Imaging

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Gold Nanoparticles in Diagnostics and Therapeutics for Human Cancer

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Nanomaterials as photothermal therapeutic agents

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Metal nanoclusters: novel probes for diagnostic and therapeutic applications

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Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine

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Gold Nanocages as Photothermal Transducers for Cancer Treatment

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Investigating the optimal size of anticancer nanomedicine

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Applications of nanoparticles in biomedical imaging

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Nanooncology: The future of cancer diagnosis and therapy

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Carbon-based nanomaterials as an emerging platform for theranostics

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Light‐Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo

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H 2 O 2 -responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay

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Nanotheranostics for personalized medicine

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A Review of Clinical Translation of Inorganic Nanoparticles

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Biologically Targeted Magnetic Hyperthermia: Potential and Limitations

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Near-infrared light-controllable on-demand antibiotics release using thermo-sensitive hydrogel-based drug reservoir for combating bacterial infection

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Colloidal gold nanoparticles: a novel nanoparticle platform for developing multifunctional tumor‐targeted drug delivery vectors

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Chitosan-Based Nanomaterials for Drug Delivery

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Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics

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Clinical cancer nanomedicine

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Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA

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Cloaking nanoparticles with protein corona shield for targeted drug delivery.

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X-ray-activated nanosystems for theranostic applications

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Antimicrobial Activity of Carbon-Based Nanoparticles

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Metal–Organic‐Framework‐Assisted In Vivo Bacterial Metabolic Labeling and Precise Antibacterial Therapy

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Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis

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Graphene-Based Sensors for Human Health Monitoring

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Integrin αvβ3‐targeted cancer therapy

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Self‐Assembling Endogenous Biliverdin as a Versatile Near‐Infrared Photothermal Nanoagent for Cancer Theranostics

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Responsive Theranostic Systems: Integration of Diagnostic Imaging Agents and Responsive Controlled Release Drug Delivery Carriers

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Inorganic nanoparticles engineered to attack bacteria

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PRINT: A Novel Platform Toward Shape and Size Specific Nanoparticle Theranostics

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Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors

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A Gold/Silver Hybrid Nanoparticle for Treatment and Photoacoustic Imaging of Bacterial Infection

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Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease

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A Novel Theranostic Nanoplatform Based on Pd@Pt‐PEG‐Ce6 for Enhanced Photodynamic Therapy by Modulating Tumor Hypoxia Microenvironment

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Calcium-based biomaterials for diagnosis, treatment, and theranostics

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Bacteria-responsive intelligent wound dressing: Simultaneous In situ detection and inhibition of bacterial infection for accelerated wound healing

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Mitochondrial specific photodynamic therapy by rare-earth nanoparticles mediated near-infrared graphene quantum dots

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First-in-Human Study Testing a New Radioenhancer Using Nanoparticles (NBTXR3) Activated by Radiation Therapy in Patients with Locally Advanced Soft Tissue Sarcomas

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Development of macromolecular prodrug for rheumatoid arthritis

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Gold Cube-in-Cube Based Oxygen Nanogenerator: A Theranostic Nanoplatform for Modulating Tumor Microenvironment for Precise Chemo-Phototherapy and Multimodal Imaging

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Biocompatibility and Toxicity of Graphene Quantum Dots for Potential Application in Photodynamic Therapy

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Gold Nanoclusters for Targeting Methicillin‐Resistant Staphylococcus aureus In Vivo

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Nano-graphene oxide-mediated In vivo fluorescence imaging and bimodal photodynamic and photothermal destruction of tumors

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A new technology of microdispersed silver in polyurethane induces antimicrobial activity in central venous catheters

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Sensing Using Rare-Earth-Doped Upconversion Nanoparticles

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Theranostic 2D ultrathin MnO2 nanosheets with fast responsibility to endogenous tumor microenvironment and exogenous NIR irradiation

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Magnetic Iron Oxide Nanoparticles As Drug Carriers: Clinical Relevance

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AGuIX ® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

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Tumor Microenvironment-Responsive Ultrasmall Nanodrug Generators with Enhanced Tumor Delivery and Penetration

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Recent advances in nanotheranostics for triple negative breast cancer treatment

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Enhancing tumor penetration of nanomedicines

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Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging

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Dextran sulfate nanoparticles as a theranostic nanomedicine for rheumatoid arthritis

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Walking the line: The fate of nanomaterials at biological barriers

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Bacteria-Activated Theranostic Nanoprobes against Methicillin-Resistant Staphylococcus aureus Infection

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Tumor microenvironment-manipulated radiocatalytic sensitizer based on bismuth heteropolytungstate for radiotherapy enhancement

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Clinically-translated silica nanoparticles as dual-modality cancer-targeted probes for image-guided surgery and interventions

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Selenium-Containing Polymers: Perspectives toward Diverse Applications in Both Adaptive and Biomedical Materials

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Graphene: A versatile platform for nanotheranostics and tissue engineering

Geetha Bai, R., Ninan, N., Muthoosamy, K., & Manickam, S. (2018) · Progress in Materials Science · doi:10.1016/j.pmatsci.2017.08.004 · Cited by 171

Design and Development of Graphene Oxide Nanoparticle/Chitosan Hybrids Showing pH-Sensitive Surface Charge-Reversible Ability for Efficient Intracellular Doxorubicin Delivery

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Seven‐tesla phase imaging of acute multiple sclerosis lesions: A new window into the inflammatory process

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Targeted Nanoparticles for Colorectal Cancer

Cisterna, B. A., Kamaly, N., Choi, W. I., Tavakkoli, A., Farokhzad, O. C., & Vilos, C. (2016) · Nanomedicine · doi:10.2217/nnm-2016-0194 · Cited by 166

Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis

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Lipid-Based Nanoparticles as a Potential Delivery Approach in the Treatment of Rheumatoid Arthritis

Chuang, S.-Y., Lin, C.-H., Huang, T.-H., & Fang, J.-Y. (2018) · Nanomaterials · doi:10.3390/nano8010042 · Cited by 165

Ultrasmall Superparamagnetic Particles of Iron Oxide in Patients With Acute Myocardial Infarction: Early Clinical Experience

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pH-sensitive polymeric micelles for targeted delivery to inflamed joints

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Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in-human, open-label, dose-escalation phase I study with expansion cohort

Burris, H. A., Bakewell, S. J., Bendell, J. C., Infante, J. R., Jones, S. F., Spigel, D. R., Weiss, G. J., Ramanathan, R. K., Ogden, A., & Hoff, D. D. V. (2016) · ESMO Open · doi:10.1136/esmoopen-2016-000154 · Cited by 157

Big Potential from Small Agents: Nanoparticles for Imaging-Based Companion Diagnostics

Ehlerding, E. B., Grodzinski, P. A., Cai, W., & Liu, C. H. (2018) · ACS Nano · doi:10.1021/acsnano.7b07252 · Cited by 156

Targeted delivery of hyaluronic acid-coated solid lipid nanoparticles for rheumatoid arthritis therapy

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Hierarchically targetable polysaccharide-coated solid lipid nanoparticles as an oral chemo/thermotherapy delivery system for local treatment of colon cancer

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PD-1/PD-L1 Inhibitors in Cervical Cancer

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Imaging Pancreatic Cancer with a Peptide−Nanoparticle Conjugate Targeted to Normal Pancreas

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Drug-loaded gold/iron/gold plasmonic nanoparticles for magnetic targeted chemo-photothermal treatment of rheumatoid arthritis

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Light-triggered theranostic liposomes for tumor diagnosis and combined photodynamic and hypoxia-activated prodrug therapy

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Recent advances in nanomedicines for the treatment of rheumatoid arthritis

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Surface Ligand Chemistry of Gold Nanoclusters Determines Their Antimicrobial Ability

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Combined targeted therapy and immunotherapy in melanoma: a review of the impact on the tumor microenvironment and outcomes of early clinical trials

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Dual function luminescent transition metal complexes for cancer theranostics: The combination of diagnosis and therapy

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Fibrin-Targeted and H 2 O 2 -Responsive Nanoparticles as a Theranostics for Thrombosed Vessels

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Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer

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Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle Delivery

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Gold Nanotheranostics: Proof-of-Concept or Clinical Tool?

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Molecularly Engineered Theranostic Nanoparticles for Thrombosed Vessels: H2O2-Activatable Contrast-Enhanced Photoacoustic Imaging and Antithrombotic Therapy

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Glycyrrhetinic Acid Functionalized Graphene Oxide for Mitochondria Targeting and Cancer Treatment In Vivo

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Scavenger Receptor-Mediated Targeted Treatment of Collagen-Induced Arthritis by Dextran Sulfate-Methotrexate Prodrug

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Recent Advances in Managing Atherosclerosis via Nanomedicine

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Stimuli-Responsive Nanotheranostics for Real-Time Monitoring Drug Release by Photoacoustic Imaging

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An efficient nano-based theranostic system for multi-modal imaging-guided photothermal sterilization in gastrointestinal tract

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In Vivo Targeting and Imaging of Atherosclerosis Using Multifunctional Virus-Like Particles of Simian Virus 40

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Ruthenium complexes/polypeptide self-assembled nanoparticles for identification of bacterial infection and targeted antibacterial research

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Formation of a protein corona influences the biological identity of nanomaterials

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Cell-penetrating Peptide-modified Targeted Drug-loaded Phase-transformation Lipid Nanoparticles Combined with Low-intensity Focused Ultrasound for Precision Theranostics against Hepatocellular Carcinoma

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Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases

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Intratumoral fate of functional nanoparticles in response to microenvironment factor: Implications on cancer diagnosis and therapy

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Clinical Trials of Thermosensitive Nanomaterials: An Overview

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A Theranostic Agent for in Vivo Near-Infrared Imaging of β-Amyloid Species and Inhibition of β-Amyloid Aggregation

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Theranostic designs of biomaterials for precision medicine in cancer therapy

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Plasmonic Photothermal Therapy of Atherosclerosis With Nanoparticles: long-term Outcomes and Safety in NANOM-FIM Trial

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In vivo visualization of endogenous miR-21 using hyaluronic acid-coated graphene oxide for targeted cancer therapy

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Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis

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Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes

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Predictable Heating and Positive MRI Contrast from a Mesoporous Silica-Coated Iron Oxide Nanoparticle

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The detection, treatment, and biology of epithelial ovarian cancer

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Sequential Targeting TGF‐β Signaling and KRAS Mutation Increases Therapeutic Efficacy in Pancreatic Cancer

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A theranostic agent for cancer therapy and imaging in the second near-infrared window

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Smart Cu(II)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy of hepatocellular carcinoma

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Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation

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Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma

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Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma

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Surface Engineering of Nanoparticles for Targeted Delivery to Hepatocellular Carcinoma

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Highly Efficient Copper Sulfide‐Based Near‐Infrared Photothermal Agents: Exploring the Limits of Macroscopic Heat Conversion

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Inherent multifunctional inorganic nanomaterials for imaging-guided cancer therapy

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Multifunctional Magnetic Gold Nanomaterials for Cancer

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Theranostic micelles based on upconversion nanoparticles for dual-modality imaging and photodynamic therapy in hepatocellular carcinoma

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Interaction of graphene oxide with cell culture medium: Evaluating the fetal bovine serum protein corona formation towards in vitro nanotoxicity assessment and nanobiointeractions

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Sensitive imaging and effective capture of Cu2+: Towards highly efficient theranostics of Alzheimer's disease

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A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Combinatorial Phototherapy

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Phase 1b/2a Trial of the Superoxide Dismutase Mimetic GC4419 to Reduce Chemoradiotherapy-Induced Oral Mucositis in Patients With Oral Cavity or Oropharyngeal Carcinoma

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Novel theranostic agents for next-generation personalized medicine: small molecules, nanoparticles, and engineered mammalian cells

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Comparison of triple-lumen central venous catheters impregnated with silver nanoparticles (AgTive®) vs conventional catheters in intensive care unit patients

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Simultaneously activating highly selective ratiometric MRI and synergistic therapy in response to intratumoral oxidability and acidity

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Promoting Early Diagnosis and Precise Therapy of Hepatocellular Carcinoma by Glypican-3-Targeted Synergistic Chemo-Photothermal Theranostics

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Nanotheranostics Targeting the Tumor Microenvironment

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In situ synthesis of graphene oxide/gold nanorods theranostic hybrids for efficient tumor computed tomography imaging and photothermal therapy

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New Strategies in the Design of Nanomedicines to Oppose Uptake by the Mononuclear Phagocyte System and Enhance Cancer Therapeutic Efficacy

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Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus

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Copper sulfide: An emerging adaptable nanoplatform in cancer theranostics

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Prediction of anti-cancer nanotherapy efficacy by imaging

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Self-Luminescing Theranostic Nanoreactors with Intraparticle Relayed Energy Transfer for Tumor Microenvironment Activated Imaging and Photodynamic Therapy

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Lanthanide-doped nanoparticles conjugated with an anti-CD33 antibody and a p53-activating peptide for acute myeloid leukemia therapy

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Metal-involved theranostics: An emerging strategy for fighting Alzheimer’s disease

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pH-sensitive zwitterionic coating of gold nanocages improves tumor targeting and photothermal treatment efficacy

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Characterization of liposome-containing SPIONs conjugated with anti-CD20 developed as a novel theranostic agent for central nervous system lymphoma

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Low-intensity focused ultrasound (LIFU)-activated nanodroplets as a theranostic agent for noninvasive cancer molecular imaging and drug delivery

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Nanotheranostics, a future remedy of neurological disorders

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Nanoparticle‐based approaches to immune tolerance for the treatment of autoimmune diseases

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Double-receptor-targeting multifunctional iron oxide nanoparticles drug delivery system for the treatment and imaging of prostate cancer

Ahmed, M. S. U., Salam, A. B., Yates, C. C., Willian, K. R., Jaynes, J. M., Turner, T., & Abdalla, M. O. A. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s139011 · Cited by 64

Animal models for analysis of immunological responses to nanomaterials: Challenges and considerations

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A novel pH-sensitive targeting polysaccharide-gold nanorod conjugate for combined photothermal-chemotherapy of breast cancer

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Folic acid on iron oxide nanoparticles: platform with high potential for simultaneous targeting, MRI detection and hyperthermia treatment of lymph node metastases of prostate cancer

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Nanoplumbers: biomaterials to fight cardiovascular diseases

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Targeting Oxidative Stress Using Nanoparticles as a Theranostic Strategy for Cardiovascular Diseases

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Conjugation of a peptide autoantigen to gold nanoparticles for intradermally administered antigen specific immunotherapy

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Oxygen and indocyanine green loaded phase-transition nanoparticle-mediated photo-sonodynamic cytotoxic effects on rheumatoid arthritis fibroblast-like synoviocytes

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Radiologic Assessment of Lymph Nodes in Oncologic Patients

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High-Density Lipoprotein-like Magnetic Nanostructures (HDL-MNS): Theranostic Agents for Cardiovascular Disease

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Tumor-microenvironment controlled nanomicelles with AIE property for boosting cancer therapy and apoptosis monitoring

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Au Hollow Nanorods-Chimeric Peptide Nanocarrier for NIR-II Photothermal Therapy and Real-time Apoptosis Imaging for Tumor Theranostics

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A phase 0 first-in-human study using NU-0129: A gold base spherical nucleic acid (SNA) nanoconjugate targeting BCL2L12 in recurrent glioblastoma patients.

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Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone®) increases antibody response, cellular immunity, and antigenically drifted protection

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Real-time in situ analysis of biocorona formation and evolution on silica nanoparticles in defined and complex biological environments

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Oxygenated theranostic nanoplatforms with intracellular agglomeration behavior for improving the treatment efficacy of hypoxic tumors

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Gold Nanorods-Based Smart Nanoplatforms for Synergic Thermotherapy and Chemotherapy of Tumor Metastasis

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Gd-DTPA-coupled Ag 2 Se quantum dots for dual-modality magnetic resonance imaging and fluorescence imaging in the second near-infrared window

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Characterisation of liposomes containing aminolevulinic acid and derived esters

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Nanotheranostic approaches for management of bloodstream bacterial infections

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Recent progress in blood-brain barrier transportation research

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Photodynamic therapy at ultra-low NIR laser power and X-Ray imaging using Cu3BiS3 nanocrystals

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Gadolinium-Based Nanoparticles for Theranostic MRI-Guided Radiosensitization in Hepatocellular Carcinoma

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Free-Radical-Assisted Rapid Synthesis of Graphene Quantum Dots and Their Oxidizability Studies

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Engineering graphene oxide with ultrasmall SPIONs and smart drug release for cancer theranostics

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SNS01-T Modulation of eIF5A Inhibits B-cell Cancer Progression and Synergizes With Bortezomib and Lenalidomide

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Tumor Microenvironment-Responsive Nanoshuttles with Sodium Citrate Modification for Hierarchical Targeting and Improved Tumor Theranostics

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Ultrasmall Renally Clearable Silica Nanoparticles Target Prostate Cancer

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Block Copolymer Based Nanoparticles for Theranostic Intervention of Cervical Cancer: Synthesis, Pharmacokinetics, and in Vitro/in Vivo Evaluation in HeLa Xenograft Models

Dumoga, S., Rai, Y., Bhatt, A. N., Tiwari, A. K., Singh, S. K., Mishra, A. K., & Kakkar, D. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b04982 · Cited by 39

Radioimmunoconjugates for treating cancer: recent advances and current opportunities

Bourgeois, M., Bailly, C., Frindel, M., Guérard, F., Chérel, M., Faivre-Chauvet, A., Kraeber‐Bodéré, F., & Bodet‐Milin, C. (2017) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2017.1322577 · Cited by 38

Unraveling the Safety Profile of Nanoscale Particles and Materials - From Biomedical to Environmental Applications

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Tumor-adapting and tumor-remodeling AuNR@dendrimer-assembly nanohybrids overcome impermeable multidrug-resistant cancer

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Serum protein corona-responsive autophagy tuning in cells

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Synergy and translation of allogenic bone marrow stem cells after photodynamic treatment of rheumatoid arthritis with tetra sulfonatophenyl porphyrin and TiO2 nanowhiskers

Rehman, F. U., Zhao, C., Wu, C., Li, X., Jiang, H., Selke, M., & Wang, X. (2016) · Nano Research · doi:10.1007/s12274-016-1208-5 · Cited by 35

Biocompatible tumor-targeting nanocomposites based on CuS for tumor imaging and photothermal therapy

Liang, L., Peng, S., Yuan, Z., Wei, C., He, Y., Zheng, J., Gu, Y., & Chen, H. (2018) · RSC Advances · doi:10.1039/c7ra12796k · Cited by 35

Cu–Au alloy nanostructures coated with aptamers: a simple, stable and highly effective platform for in vivo cancer theranostics

Ye, X., Shi, H., He, X., Yu, Y., He, D., Tang, J., Lei, Y., & Wang, K. (2015) · Nanoscale · doi:10.1039/c5nr07017a · Cited by 34

Multi-layered tumor-targeting photothermal-doxorubicin releasing nanotubes eradicate tumors in vivo with negligible systemic toxicity

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Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival

Dufort, S., Appelboom, G., Verry, C., Barbier, E., Lux, F., Bräuer‐Krisch, E., Sancey, L., Chang, S. D., Zhang, M., Roux, S., et al. (2019) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2019.05.065 · Cited by 33

Anticancer drug-loaded quantum dots engineered polymeric nanoparticles: Diagnosis/therapy combined approach

Belletti, D., Riva, G., Luppi, M., Tosi, G., Forni, F., Vandelli, M. A., Ruozi, B., & Pederzoli, F. (2017) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2017.07.020 · Cited by 31

Artemisinin-Loaded Mesoporous Nanoplatform for pH-Responsive Radical Generation Synergistic Tumor Theranostics

Liu, L., Liu, Y. L., Ma, L., Mao, F., Jiang, A., Liu, D., Wang, L., Jia, Q., & Zhou, J. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b18320 · Cited by 31

Multi-functionalised graphene nanoflakes as tumour-targeting theranostic drug-delivery vehicles

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Recent advances in cell-mediated nanomaterial delivery systems for photothermal therapy

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Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

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Where Is Nano Today and Where Is It Headed? A Review of Nanomedicine and the Dilemma of Nanotoxicology

Domingues, C., Santos, A., Alvarez-Lorenzo, C., Concheiro, A., Jarak, I., Veiga, F., Barbosa, I., Dourado, M., & Figueiras, A. (2022) · ACS Nano · doi:10.1021/acsnano.2c00128 · Cited by 235