Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

Vale, W., Spiess, J., Rivier, C., & Rivier, J. (1981) · Science · doi:10.1126/science.6267699 · Cited by 3,965

Therapeutic Peptides: Current Applications and Future Directions

Wang, L., Wang, N., Zhang, W., Cheng, X., Yan, Z., Shao, G., Wang, X., Wang, R., & Fu, C. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00904-4 · Cited by 2,131

Solid Phase Peptide Synthesis

Stewart, J. M. (1976) · Journal of Macromolecular Science: Part A - Chemistry · doi:10.1080/00222337608068099 · Cited by 1,767

Synthesis and Applications of Small Molecule Libraries

Thompson, L. A., & Ellman, J. A. (1996) · Chemical Reviews · doi:10.1021/cr9402081 · Cited by 1,452

Sequence-Controlled Polymers

Lutz, J.-F., Ouchi, M., Liu, D. R., & Sawamoto, M. (2013) · Science · doi:10.1126/science.1238149 · Cited by 1,381

Dendron-Mediated Self-Assembly, Disassembly, and Self-Organization of Complex Systems

Rosen, B. M., Wilson, C. J., Wilson, D. A., Peterca, M., Imam, M. R., & Percec, V. (2009) · Chemical Reviews · doi:10.1021/cr900157q · Cited by 1,204

Solid Phase Synthesis

Merrifield, B. (1986) · Science · doi:10.1126/science.3961484 · Cited by 1,005

Automated Solid-Phase Synthesis of Oligosaccharides

Plante, O. J., Palmacci, E. R., & Seeberger, P. H. (2001) · Science · doi:10.1126/science.1057324 · Cited by 933

Automating drug discovery

Schneider, G. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.232 · Cited by 910

Strategies for epitope analysis using peptide synthesis

Geysen, H. M., Rodda, S. J., Mason, T. J., Tribbick, G., & Schoofs, P. G. (1987) · Journal of Immunological Methods · doi:10.1016/0022-1759(87)90085-8 · Cited by 868

Amino Acid-Protecting Groups

Isidro-Llobet, A., Álvarez, M., & Albericio, F. (2009) · Chemical Reviews · doi:10.1021/cr800323s · Cited by 850

N -Methylated Cyclic RGD Peptides as Highly Active and Selective α V β 3 Integrin Antagonists

Dechantsreiter, M. A., Planker, E., Mathä, B., Lohof, E., Hölzemann, G., Jonczyk, A., Goodman, S. L., & Kessler, H. (1999) · Journal of Medicinal Chemistry · doi:10.1021/jm970832g · Cited by 838

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

Baron, J. L., Madri, J. A., Ruddle, N. H., Hashim, G., & Janeway, C. A. (1993) · The Journal of experimental medicine · doi:10.1084/jem.177.1.57 · Cited by 835

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

Mojsov, S., Heinrich, G., Wilson, I. B., Ravazzola, M., Orci, L., & Habener, J. F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67324-7 · Cited by 724

Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology

Hackeng, T. M., Griffin, J. H., & Dawson, P. E. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10068 · Cited by 675

Protecting-group-free synthesis as an opportunity for invention

Young, I. S., & Baran, P. S. (2009) · Nature Chemistry · doi:10.1038/nchem.216 · Cited by 667

Combinatorial synthesis — the design of compound libraries and their application to drug discovery

Terrett, N. K., Gardner, M., Gordon, D. W., Kobylecki, R. J., & Steele, J. (1995) · Tetrahedron · doi:10.1016/0040-4020(95)00467-m · Cited by 659

Native Chemical Ligation and Extended Methods: Mechanisms, Catalysis, Scope, and Limitations

Agouridas, V., El Mahdi, O., Diemer, V., Cargoët, M., Monbaliu, J.-C. M., & Melnyk, O. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00712 · Cited by 650

Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences

Coin, I., Beyermann, M., & Bienert, M. (2007) · Nature Protocols · doi:10.1038/nprot.2007.454 · Cited by 638

Diversity-oriented synthesis: Exploring the intersections between chemistry and biology

Tan, D. S. (2005) · Nature Chemical Biology · doi:10.1038/nchembio0705-74 · Cited by 605

Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

Lächelt, U., & Wagner, E. (2015) · Chemical Reviews · doi:10.1021/cr5006793 · Cited by 600

New Designs of Macroporous Polymers and Supports: From Separation to Biocatalysis

Svec, F., & Fréchet, J. M. J. (1996) · Science · doi:10.1126/science.273.5272.205 · Cited by 586

The Current Status of Heterocyclic Combinatorial Libraries

Nefzi, A., Ostresh, J. M., & Houghten, R. A. (1997) · Chemical Reviews · doi:10.1021/cr960010b · Cited by 586

Biochemical properties and subcellular distribution of an N-type calcium hannel α1 subunit

Westenbroek, R. E., Hell, J. W., Warner, C., Dubel, S. J., Snutch, T. P., & Catterall, W. A. (1992) · Neuron · doi:10.1016/0896-6273(92)90069-p · Cited by 585

Gonadotropin-Releasing Hormone Analog Design. Structure-Function Studies Toward the Development of Agonists and Antagonists: Rationale and Perspective

KARTEN, M. J., & RIVIER, J. E. (1986) · Endocrine Reviews · doi:10.1210/edrv-7-1-44 · Cited by 560

Automated Synthesis of Peptides: Solid-phase peptide synthesis, a simple and rapid synthetic method, has now been automated.

Merrifield, R. B. (1965) · Science · doi:10.1126/science.150.3693.178 · Cited by 540

Molecular clocks

Robinson, N. E., & Robinson, A. B. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.3.944 · Cited by 532

Self‐Assembled Peptide‐Based Nanomaterials for Biomedical Imaging and Therapy

Qi, G., Gao, Y., Wang, L., & Wang, H. (2018) · Advanced Materials · doi:10.1002/adma.201703444 · Cited by 527

C fragment of lipotropin has a high affinity for brain opiate receptors

BRADBURY, A. F., SMYTH, D. G., SNELL, C. R., BIRDSALL, N. J. M., & HULME, E. C. (1976) · Nature · doi:10.1038/260793a0 · Cited by 489

Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons

Westenbroek, R. E., Merrick, D. K., & Catterall, W. A. (1989) · Neuron · doi:10.1016/0896-6273(89)90238-9 · Cited by 477

Combinatorial solid-state chemistry of inorganic materials

Koinuma, H., & Takeuchi, I. (2004) · Nature Materials · doi:10.1038/nmat1157 · Cited by 477

Rapid and quantitative one-pot synthesis of sequence-controlled polymers by radical polymerization

Gody, G., Maschmeyer, T., Zetterlund, P. B., & Perrier, S. (2013) · Nature Communications · doi:10.1038/ncomms3505 · Cited by 473

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production

Isidro-Llobet, A., Kenworthy, M. N., Mukherjee, S., Kopach, M. E., Wegner, K., Gallou, F., Smith, A. G., & Roschangar, F. (2019) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.8b03001 · Cited by 473

Single-molecule protein folding: Diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2

Deniz, A. A., Laurence, T. A., Beligere, G. S., Dahan, M., Martin, A. B., Chemla, D. S., Dawson, P. E., Schultz, P. G., & Weiss, S. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.090104997 · Cited by 469

Inhibition of Lymphocyte Proliferation by a Synthetic Peptide Homologous to Retroviral Envelope Proteins

Cianciolo, G. J., Copeland, T. D., Oroszlan, S., & Snyderman, R. (1985) · Science · doi:10.1126/science.2996136 · Cited by 451

Advance in peptide-based drug development: delivery platforms, therapeutics and vaccines

Xiao, W., Jiang, W., Chen, Z., Huang, Y., Mao, J., Zheng, W., Hu, Y., & Shi, J. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02107-5 · Cited by 449

Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics

Manning, M., Misicka, A., Olma, A., Bankowski, K., Stoev, S., Chini, B., Durroux, T., Mouillac, B., Corbani, M., & Guillon, G. (2012) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2012.02303.x · Cited by 423

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion.

Humphries, M. J., Akiyama, S. K., Komoriya, A., Olden, K., & Yamada, K. M. (1986) · The Journal of cell biology · doi:10.1083/jcb.103.6.2637 · Cited by 438

Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. Critical role of NH2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities.

Clark-Lewis, I., Schumacher, C., Baggiolini, M., & Moser, B. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54472-0 · Cited by 425

Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future

Ray, A., & Nordén, B. (2000) · The FASEB Journal · doi:10.1096/fasebj.14.9.1041 · Cited by 416

Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein

Palczewski, K., Subbaraya, I., Gorczyca, W. A., Helekar, B. S., Ruiz, C. C., Ohguro, H., Huang, J., Zhao, X., Crabb, J. W., Johnson, R. S., et al. (1994) · Neuron · doi:10.1016/0896-6273(94)90355-7 · Cited by 371

Iterative exponential growth of stereo- and sequence-controlled polymers

Barnes, J. C., Ehrlich, D. J. C., Gao, A. X., Leibfarth, F. A., Jiang, Y., Zhou, E., Jamison, T. F., & Johnson, J. A. (2015) · Nature Chemistry · doi:10.1038/nchem.2346 · Cited by 361

Synthesis of proteins by automated flow chemistry

Hartrampf, N., Saebi, A., Poskus, M., Gates, Z. P., Callahan, A. J., Cowfer, A. E., Hanna, S., Antilla, S., Schissel, C. K., Quartararo, A. J., et al. (2020) · Science · doi:10.1126/science.abb2491 · Cited by 367

Peptide and Amide Bond-Containing Dendrimers

Crespo, L., Sanclimens, G., Pons, M., Giralt, E., Royo, M., & Albericio, F. (2005) · Chemical Reviews · doi:10.1021/cr030449l · Cited by 356

Identification of two distinct regions of the type III connecting segment of human plasma fibronectin that promote cell type-specific adhesion.

Humphries, M. J., Komoriya, A., Akiyama, S. K., Olden, K., & Yamada, K. M. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48327-5 · Cited by 347

Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta 1-adrenoceptor with positive chronotropic effect.

Magnusson, Y., Wallukat, G., Waagstein, F., Hjalmarson, A., & Hoebeke, J. (1994) · Circulation · doi:10.1161/01.cir.89.6.2760 · Cited by 347

Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

Verheij, C., Bakker, C. E., de Graaff, E., Keulemans, J., Willemsen, R., Verkerk, A. J. M. H., Galjaard, H., Reuser, A. J. J., Hoogeveen, A. T., & Oostra, B. A. (1993) · Nature · doi:10.1038/363722a0 · Cited by 343

Pega: a flow stable polyethylene glycol dimethyl acrylamide copolymer for solid phase synthesis.

Meldal, M. (1992) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)79604-3 · Cited by 342

Solid‐Phase synthesis of peptide nucleic acids

Christensen, L., Fitzpatrick, R., Gildea, B., Petersen, K. H., Hansen, H. F., Koch, T., Egholm, M., Buchardt, O., Nielsen, P. E., Coull, J., et al. (1995) · Journal of Peptide Science · doi:10.1002/psc.310010304 · Cited by 337

Discovery, Synthesis, and Structure–Activity Relationships of Conotoxins

Akondi, K. B., Muttenthaler, M., Dutertre, S., Kaas, Q., Craik, D. J., Lewis, R. J., & Alewood, P. F. (2014) · Chemical Reviews · doi:10.1021/cr400401e · Cited by 323

Umpolung reactivity in amide and peptide synthesis

Shen, B., Makley, D. M., & Johnston, J. N. (2010) · Nature · doi:10.1038/nature09125 · Cited by 318

Mechanism of rhodopsin kinase activation

Palczewski, K., Buczyłko, J., Kaplan, M. W., Polans, A. S., & Crabb, J. W. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98787-9 · Cited by 305

The 220-kDa Rim Protein of Retinal Rod Outer Segments Is a Member of the ABC Transporter Superfamily

Illing, M., Molday, L. L., & Molday, R. S. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.15.10303 · Cited by 304

Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1

Sabatier, J. M., Vives, E., Mabrouk, K., Benjouad, A., Rochat, H., Duval, A., Hue, B., & Bahraoui, E. (1991) · Journal of Virology · doi:10.1128/jvi.65.2.961-967.1991 · Cited by 302

Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents☆

MANNING, M., STOEV, S., CHINI, B., DURROUX, T., MOUILLAC, B., & GUILLON, G. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00437-8 · Cited by 296

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein

Kris, R. M., Lax, I., Gullick, W., Waterfield, M. D., Ullrich, A., Fridkin, M., & Schlessinger, J. (1985) · Cell · doi:10.1016/0092-8674(85)90210-7 · Cited by 295

Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene.

De Jongh, K. S., Warner, C., & Catterall, W. A. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77174-3 · Cited by 290

A General Approach to Sequence-Controlled Polymers Using Macrocyclic Ring Opening Metathesis Polymerization

Gutekunst, W. R., & Hawker, C. J. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b04940 · Cited by 283

Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion

Hilpert, K., Winkler, D. F., & Hancock, R. E. (2007) · Nature Protocols · doi:10.1038/nprot.2007.160 · Cited by 278

Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.

Li, Z., Nicoll, D. A., Collins, A., Hilgemann, D. W., Filoteo, A. G., Penniston, J. T., Weiss, J. N., Tomich, J. M., & Philipson, K. D. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)35276-6 · Cited by 275

The Rat Androgen Receptor: Primary Structure, Autoregulation of its Messenger Ribonucleic Acid, and Immunocytochemical Localization of the Receptor Protein

Tan, J.-A., Joseph, D. R., Quarmby, V. E., Lubahn, D. B., Sar, M., French, F. S., & Wilson, E. M. (1988) · Molecular Endocrinology · doi:10.1210/mend-2-12-1276 · Cited by 275

Immunological Self, Nonself Discrimination

Guillet, J.-G., Lai, M.-Z., Briner, T. J., Buus, S., Sette, A., Grey, H. M., Smith, J. A., & Gefter, M. L. (1987) · Science · doi:10.1126/science.2433769 · Cited by 274

Solid-phase peptide synthesis: an overview focused on the preparation of biologically relevant peptides

Palomo, J. M. (2014) · RSC Adv. · doi:10.1039/c4ra02458c · Cited by 273

The effects of variations in the number and sequence of targeting signals on nuclear uptake.

Dworetzky, S. I., Lanford, R. E., & Feldherr, C. M. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1279 · Cited by 270

Extending the Applicability of Native Chemical Ligation

Canne, L. E., Bark, S. J., & Kent, S. B. H. (1996) · Journal of the American Chemical Society · doi:10.1021/ja960398s · Cited by 269

Functional domains of adenovirus type 5 E1a proteins

Lillie, J. W., Loewenstein, P. M., Green, M. R., & Green, M. (1987) · Cell · doi:10.1016/0092-8674(87)90175-9 · Cited by 269

DNA synthesis technologies to close the gene writing gap

Hoose, A., Vellacott, R., Storch, M., Freemont, P. S., & Ryadnov, M. G. (2023) · Nature Reviews Chemistry · doi:10.1038/s41570-022-00456-9 · Cited by 268

Peptoids and Polypeptoids at the Frontier of Supra- and Macromolecular Engineering

Gangloff, N., Ulbricht, J., Lorson, T., Schlaad, H., & Luxenhofer, R. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00201 · Cited by 265

Histones: At the Crossroads of Peptide and Protein Chemistry

Müller, M. M., & Muir, T. W. (2015) · Chemical Reviews · doi:10.1021/cr5003529 · Cited by 247

125I-labelled d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH29]OVT: a selective oxytocin receptor ligand

Elands, J., Barberis, C., Jard, S., Tribollet, E., Dreifuss, J.-J., Bankowski, K., Manning, M., & Sawyer, W. H. (1988) · European Journal of Pharmacology · doi:10.1016/0014-2999(88)90778-9 · Cited by 245

Polysarcosine-containing copolymers: synthesis, characterization, self-assembly, and applications

Birke, A., Ling, J., & Barz, M. (2018) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2018.01.002 · Cited by 229

Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor–coactivator interactions

Leduc, A.-M., Trent, J. O., Wittliff, J. L., Bramlett, K. S., Briggs, S. L., Chirgadze, N. Y., Wang, Y., Burris, T. P., & Spatola, A. F. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1934759100 · Cited by 222

The greening of peptide synthesis

Lawrenson, S. B., Arav, R., & North, M. (2017) · Green Chemistry · doi:10.1039/c7gc00247e · Cited by 205

Peptides As Therapeutics with Enhanced Bioactivity

Goodwin, D., Simerska, P., & Toth, I. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712803251548 · Cited by 176

The limits of precision monomer placement in chain growth polymerization

Gody, G., Zetterlund, P. B., Perrier, S., & Harrisson, S. (2016) · Nature Communications · doi:10.1038/ncomms10514 · Cited by 170

N-Triazinylammonium Tetrafluoroborates. A New Generation of Efficient Coupling Reagents Useful for Peptide Synthesis

Kamiński, Z. J., Kolesińska, B., Kolesińska, J., Sabatino, G., Chelli, M., Rovero, P., Błaszczyk, M., Główka, M. L., & Papini, A. M. (2005) · Journal of the American Chemical Society · doi:10.1021/ja054260y · Cited by 155

Process Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis

Kekessie, I., Wegner, K., Martinez, I., Kopach, M. E., White, T. D., Tom, J. K., Kenworthy, M. N., Gallou, F., Lopez, J., Koenig, S. G., et al. (2024) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.3c01494 · Cited by 149

Peptide-Based Functional Biomaterials for Soft-Tissue Repair

Hosoyama, K., Lazurko, C., Muñoz, M., McTiernan, C. D., & Alarcon, E. I. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00205 · Cited by 118

pH‐Dependent Binding of Synthetic β‐Amyloid Peptides to Glycosaminoglycans

Brunden, K. R., Richter‐Cook, N. J., Chaturvedi, N., & Frederickson, R. C. A. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb07453.x · Cited by 117

Synthesis and applications of mirror-image proteins

Harrison, K., Mackay, A. S., Kambanis, L., Maxwell, J. W. C., & Payne, R. J. (2023) · Nature Reviews Chemistry · doi:10.1038/s41570-023-00493-y · Cited by 104

Mirror-image T7 transcription of chirally inverted ribosomal and functional RNAs

Xu, Y., & Zhu, T. F. (2022) · Science · doi:10.1126/science.abm0646 · Cited by 94

The Evolution of DNA-Templated Synthesis as a Tool for Materials Discovery

O’Reilly, R. K., Turberfield, A. J., & Wilks, T. R. (2017) · Accounts of Chemical Research · doi:10.1021/acs.accounts.7b00280 · Cited by 92

Kinetic Analysis of the Interaction of the Copper Chaperone Atox1 with the Metal Binding Sites of the Menkes Protein

Strausak, D., Howie, M. K., Firth, S. D., Schlicksupp, A., Pipkorn, R., Multhaup, G., & Mercer, J. F. B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212437200 · Cited by 71

Continuous‐Flow Solid‐Phase Peptide Synthesis: A Revolutionary Reduction of the Amino Acid Excess

Mándity, I. M., Olasz, B., Ötvös, S. B., & Fülöp, F. (2014) · ChemSusChem · doi:10.1002/cssc.201402436 · Cited by 65

Solid‐phase peptide synthesis using acetonitrile as a solvent in combination with PEG‐based resins

Acosta, G. A., del Fresno, M., Paradis‐Bas, M., Rigau‐DeLlobet, M., Côté, S., Royo, M., & Albericio, F. (2009) · Journal of Peptide Science · doi:10.1002/psc.1158 · Cited by 63

Molecular Analysis of the Interaction between the Hematopoietic Master Transcription Factors GATA-1 and PU.1

Liew, C. W., Rand, K. D., Simpson, R. J. Y., Yung, W. W., Mansfield, R. E., Crossley, M., Proetorius-Ibba, M., Nerlov, C., Poulsen, F. M., & Mackay, J. P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602830200 · Cited by 63

Deep Learning for Prediction and Optimization of Fast-Flow Peptide Synthesis

(2020) · doi:10.1021/acscentsci.0c00979 · Cited by 61

Inverse Peptide Synthesis Using Transient Protected Amino Acids

Liu, T., Peng, Z., Lai, M., Hu, L., & Zhao, J. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c00314 · Cited by 58

Definition and transfer of a serological epitope specific for peptide-empty forms of MHC class I

Yu, Y. Y. L., Myers, N. B., Hilbert, C. M., Harris, M. R., Balendiran, G. K., & Hansen, T. H. (1999) · International Immunology · doi:10.1093/intimm/11.12.1897 · Cited by 56

Ynamide‐Mediated Peptide Bond Formation: Mechanistic Study and Synthetic Applications

Xu, S., Jiang, D., Peng, Z., Hu, L., Liu, T., Zhao, L., & Zhao, J. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202212247 · Cited by 46

Recent Advances in the Solid- and Solution-Phase Synthesis of Peptides and Proteins Using Microflow Technology

Masui, H., & Fuse, S. (2022) · Organic Process Research & Development · doi:10.1021/acs.oprd.2c00074 · Cited by 38

Structural requirements for biological activity of glucagon‐like peptide‐I

MOJSOV, S. (1992) · International Journal of Peptide and Protein Research · doi:10.1111/j.1399-3011.1992.tb00309.x · Cited by 33

Practical N-to-C peptide synthesis with minimal protecting groups

(2023) · doi:10.1038/s42004-023-01030-0 · Cited by 27

Bioactive N‐terminal undecapeptides derived from parathyroid hormone: the role of α‐helicity*

Barazza, A., Wittelsberger, A., Fiori, N., Schievano, E., Mammi, S., Toniolo, C., Alexander, J. M., Rosenblatt, M., Peggion, E., & Chorev, M. (2005) · The Journal of Peptide Research · doi:10.1111/j.1399-3011.2005.00207.x · Cited by 23

Multigram-Scale Synthesis of Short Peptides via a Simplified Repetitive Solution-Phase Procedure

Meneses, C., Nicoll, S. L., & Trembleau, L. (2010) · The Journal of Organic Chemistry · doi:10.1021/jo902116p · Cited by 22

Through the looking glass: milestones on the road towards mirroring life

Rohden, F., Hoheisel, J. D., & Wieden, H.-J. (2021) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2021.06.006 · Cited by 18

DNA-based random number generation in security circuitry

Gearheart, C. M., Arazi, B., & Rouchka, E. C. (2010) · Biosystems · doi:10.1016/j.biosystems.2010.03.005 · Cited by 17

Functional Ambidexterity of an Ancient Nucleic Acid‐Binding Domain

Weil‐Ktorza, O., Naveh‐Tassa, S., Fridmann‐Sirkis, Y., Despotović, D., Cherukuri, K. P., Corlett, T., Levy, Y., Metanis, N., & Longo, L. M. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202505188 · Cited by 12

Revolutionizing orthopedic healthcare: a systematic review unveiling recombinant antimicrobial peptides

Pennone, V., Rosini, E., Mascheroni, E., Gianola, S., Castellini, G., Bargeri, S., & Lovati, A. B. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1370826 · Cited by 8

Targeting Dysregulated Ion Channels in Liver Tumors with Venom Peptides

Achimba, F., Faezov, B., Cohen, B., Dunbrack, R., & Holford, M. (2024) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-23-0256 · Cited by 6