High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Scaffidi, P., Misteli, T., & Bianchi, M. E. (2002) · Nature · doi:10.1038/nature00858 · Cited by 4,221

Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases

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Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

Wang, H., Liao, H., Ochani, M., Justiniani, M., Lin, X., Yang, L., Al-Abed, Y., Wang, H., Metz, C., Miller, E. J., et al. (2004) · Nature Medicine · doi:10.1038/nm1124 · Cited by 1,170

Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress

Lander, H. M., Tauras, J. M., Ogiste, J. S., Hori, O., Moss, R. A., & Schmidt, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17810 · Cited by 813

The receptor for advanced glycation end‐products (RAGE) directly binds to ERK by a D‐domain‐like docking site

Ishihara, K., Tsutsumi, K., Kawane, S., Nakajima, M., & Kasaoka, T. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00846-9 · Cited by 201

Pattern Recognition Receptors and Inflammation

Takeuchi, O., & Akira, S. (2010) · Cell · doi:10.1016/j.cell.2010.01.022 · Cited by 8,895

The Beclin 1 network regulates autophagy and apoptosis

Kang, R., Zeh, H. J., Lotze, M. T., & Tang, D. (2011) · Cell Death & Differentiation · doi:10.1038/cdd.2010.191 · Cited by 2,485

Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production

Naugler, W. E., Sakurai, T., Kim, S., Maeda, S., Kim, K., Elsharkawy, A. M., & Karin, M. (2007) · Science · doi:10.1126/science.1140485 · Cited by 1,955

TLR4 enhances TGF-β signaling and hepatic fibrosis

Seki, E., De Minicis, S., Österreicher, C. H., Kluwe, J., Osawa, Y., Brenner, D. A., & Schwabe, R. F. (2007) · Nature Medicine · doi:10.1038/nm1663 · Cited by 1,942

How dying cells alert the immune system to danger

Kono, H., & Rock, K. L. (2008) · Nature Reviews Immunology · doi:10.1038/nri2215 · Cited by 1,737

Induction of autophagy by spermidine promotes longevity

Eisenberg, T., Knauer, H., Schauer, A., Büttner, S., Ruckenstuhl, C., Carmona-Gutierrez, D., Ring, J., Schroeder, S., Magnes, C., Antonacci, L., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1975 · Cited by 1,680

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Vogl, T., Tenbrock, K., Ludwig, S., Leukert, N., Ehrhardt, C., van Zoelen, M. A. D., Nacken, W., Foell, D., van der Poll, T., Sorg, C., et al. (2007) · Nature Medicine · doi:10.1038/nm1638 · Cited by 1,418

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

Moussion, C., Ortega, N., & Girard, J.-P. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003331 · Cited by 1,179

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

Tsung, A., Sahai, R., Tanaka, H., Nakao, A., Fink, M. P., Lotze, M. T., Yang, H., Li, J., Tracey, K. J., Geller, D. A., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20042614 · Cited by 1,113

Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens

Sternberg, E. M. (2006) · Nature Reviews Immunology · doi:10.1038/nri1810 · Cited by 1,064

The role of JAK/STAT signaling pathway and its inhibitors in diseases.

Xin, P., Xu, X., Deng, C., Liu, S., Wang, Y., Zhou, X., Ma, H., Wei, D., & Sun, S. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106210 · Cited by 1,010

HMGB1 in health and disease

Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2014.05.001 · Cited by 956

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

Carriere, V., Roussel, L., Ortega, N., Lacorre, D.-A., Americh, L., Aguilar, L., Bouche, G., & Girard, J.-P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606854104 · Cited by 966

Endogenous HMGB1 regulates autophagy

Tang, D., Kang, R., Livesey, K. M., Cheh, C.-W., Farkas, A., Loughran, P., Hoppe, G., Bianchi, M. E., Tracey, K. J., Zeh, H. J., et al. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200911078 · Cited by 951

Consensus guidelines for the detection of immunogenic cell death

Kepp, O., Senovilla, L., Vitale, I., Vacchelli, E., Adjemian, S., Agostinis, P., Apetoh, L., Aranda, F., Barnaba, V., Bloy, N., et al. (2014) · OncoImmunology · doi:10.4161/21624011.2014.955691 · Cited by 832

HMGB1: Endogenous Danger Signaling

Klune, J. R., Dhupar, R., Cardinal, J., Billiar, T. R., & Tsung, A. (2008) · Molecular Medicine · doi:10.2119/2008-00034.klune · Cited by 762

Mincle is an ITAM-coupled activating receptor that senses damaged cells

Yamasaki, S., Ishikawa, E., Sakuma, M., Hara, H., Ogata, K., & Saito, T. (2008) · Nature Immunology · doi:10.1038/ni.1651 · Cited by 740

Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response

Festjens, N., Vanden Berghe, T., & Vandenabeele, P. (2006) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2006.06.014 · Cited by 710

S100A8 and S100A9 in inflammation and cancer

Gebhardt, C., Németh, J., Angel, P., & Hess, J. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.05.017 · Cited by 696

Sterile inflammation in the liver

Kubes, P., & Mehal, W. Z. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.09.008 · Cited by 666

Senescent cells as a source of inflammatory factors for tumor progression

Davalos, A. R., Coppe, J.-P., Campisi, J., & Desprez, P.-Y. (2010) · Cancer and Metastasis Reviews · doi:10.1007/s10555-010-9220-9 · Cited by 636

Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox

Rubartelli, A., & Lotze, M. T. (2007) · Trends in Immunology · doi:10.1016/j.it.2007.08.004 · Cited by 614

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

Salminen, A., Huuskonen, J., Ojala, J., Kauppinen, A., Kaarniranta, K., & Suuronen, T. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2007.09.002 · Cited by 581

The extracellular release of HMGB1 during apoptotic cell death

Bell, C. W., Jiang, W., Reich, C. F., & Pisetsky, D. S. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00616.2005 · Cited by 538

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease

Srikanth, V., Maczurek, A., Phan, T., Steele, M., Westcott, B., Juskiw, D., & Münch, G. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.04.016 · Cited by 524

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

Tang, D., Kang, R., Cheh, C.-W., Livesey, K. M., Liang, X., Schapiro, N. E., Benschop, R., Sparvero, L. J., Amoscato, A. A., Tracey, K. J., et al. (2010) · Oncogene · doi:10.1038/onc.2010.261 · Cited by 461

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

Davalos, A. R., Kawahara, M., Malhotra, G. K., Schaum, N., Huang, J., Ved, U., Beausejour, C. M., Coppe, J.-P., Rodier, F., & Campisi, J. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201206006 · Cited by 439

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins

Bertheloot, D., & Latz, E. (2017) · Cellular & Molecular Immunology · doi:10.1038/cmi.2016.34 · Cited by 455

Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer

Kirn, D. H., & Thorne, S. H. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2545 · Cited by 402

NLRs at the intersection of cell death and immunity

Ting, J. P.-Y., Willingham, S. B., & Bergstralh, D. T. (2008) · Nature Reviews Immunology · doi:10.1038/nri2296 · Cited by 371

HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration

Gao, H.-M., Zhou, H., Zhang, F., Wilson, B. C., Kam, W., & Hong, J.-S. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3732-10.2011 · Cited by 369

Review: Systemic inflammation andAlzheimer's disease

Holmes, C. (2013) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2012.01307.x · Cited by 356

Masquerader: High Mobility Group Box-1 and Cancer

Ellerman, J. E., Brown, C. K., de Vera, M., Zeh, H. J., Billiar, T., Rubartelli, A., & Lotze, M. T. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-1953 · Cited by 355

DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury

Liesz, A., Dalpke, A., Mracsko, E., Roth, S., Zhou, W., Yang, H., Na, S.-Y., Akhisaroglu, M., Fleming, T., Eigenbrod, T., et al. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.2439-14.2015 · Cited by 334

HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy, and Cognitive Dysfunction

Paudel, Y. N., Shaikh, M. F., Chakraborti, A., Kumari, Y., Aledo-Serrano, Á., Aleksovska, K., Alvim, M. K. M., & Othman, I. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00628 · Cited by 311

Danger signals in stroke and their role on microglia activation after ischemia

Gülke, E., Gelderblom, M., & Magnus, T. (2018) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756286418774254 · Cited by 321

Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

Tang, D., Shi, Y., Kang, R., Li, T., Xiao, W., Wang, H., & Xiao, X. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0806540 · Cited by 312

The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder

Maes, M., & Carvalho, A. F. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1016-x · Cited by 306

Programmed Necrosis Induced by Asbestos in Human Mesothelial Cells Causes High-Mobility Group Box 1 Protein Release and Resultant Inflammation

Yang, H., Rivera, Z., Jube, S., Nasu, M., Bertino, P., Goparaju, C., Franzoso, G., Lotze, M. T., Krausz, T., Pass, H. I., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006542107 · Cited by 281

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-α Production in Human Monocytes

Youn, J. H., Oh, Y. J., Kim, E. S., Choi, J. E., & Shin, J.-S. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.7.5067 · Cited by 281

Neural Regulation of Hematopoiesis, Inflammation, and Cancer

Hanoun, M., Maryanovich, M., Arnal-Estapé, A., & Frenette, P. S. (2015) · Neuron · doi:10.1016/j.neuron.2015.01.026 · Cited by 265

Letter to the Glyco-Forum: Since there are PAMPs and DAMPs, there must be SAMPs? Glycan "self-associated molecular patterns" dampen innate immunity, but pathogens can mimic them

Varki, A. (2011) · Glycobiology · doi:10.1093/glycob/cwr087 · Cited by 263

Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia

Gaikwad, S., Puangmalai, N., Bittar, A., Montalbano, M., Garcia, S., McAllen, S., Bhatt, N., Sonawane, M., Sengupta, U., & Kayed, R. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109419 · Cited by 234

Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver

Mihm, S. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103104 · Cited by 232

Emerging role of Toll-like receptors in atherosclerosis

Curtiss, L. K., & Tobias, P. S. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800056-jlr200 · Cited by 225

Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome

Weber, M. D., Frank, M. G., Tracey, K. J., Watkins, L. R., & Maier, S. F. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3561-14.2015 · Cited by 215

Analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin)

Rouhiainen, A., Tumova, S., Valmu, L., Kalkkinen, N., & Rauvala, H. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0306200 · Cited by 214

Cell Death in Chondrocytes, Osteoblasts, and Osteocytes

Komori, T. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122045 · Cited by 176

IL-33 and IL-33 receptors in host defense and diseases

Oboki, K., Ohno, T., Kajiwara, N., Saito, H., & Nakae, S. (2010) · Allergology International · doi:10.2332/allergolint.10-rai-0186 · Cited by 190

Regulation of osteoclast function and bone mass by RAGE

Zhou, Z., Immel, D., Xi, C.-X., Bierhaus, A., Feng, X., Mei, L., Nawroth, P., Stern, D. M., & Xiong, W.-C. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20051947 · Cited by 178

HMGB1 Regulates RANKL-Induced Osteoclastogenesis in a Manner Dependent on RAGE

Zhou, Z., Han, J.-Y., Xi, C.-X., Xie, J.-X., Feng, X., Wang, C.-Y., Mei, L., & Xiong, W.-C. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080234 · Cited by 160

Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging

Qi, Y., Goel, R., Kim, S., Richards, E. M., Carter, C. S., Pepine, C. J., Raizada, M. K., & Buford, T. W. (2017) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.05.018 · Cited by 165

HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease

Fujita, K., Motoki, K., Tagawa, K., Chen, X., Hama, H., Nakajima, K., Homma, H., Tamura, T., Watanabe, H., Katsuno, M., et al. (2016) · Scientific Reports · doi:10.1038/srep31895 · Cited by 160

Toll-like Receptor 4 and Hepatic Fibrogenesis

Pradere, J.-P., Troeger, J., Dapito, D., Mencin, A., & Schwabe, R. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255353 · Cited by 158

CD24-Siglec G/10 discriminates danger- from pathogen-associated molecular patterns

Liu, Y., Chen, G.-Y., & Zheng, P. (2009) · Trends in Immunology · doi:10.1016/j.it.2009.09.006 · Cited by 147

Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors

Nestor, J., Arinuma, Y., Huerta, T. S., Kowal, C., Nasiri, E., Kello, N., Fujieda, Y., Bialas, A., Hammond, T., Sriram, U., et al. (2018) · Journal of Experimental Medicine · doi:10.1084/jem.20180776 · Cited by 146

The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming

Fonken, L. K., Frank, M. G., Kitt, M. M., D'Angelo, H. M., Norden, D. M., Weber, M. D., Barrientos, R. M., Godbout, J. P., Watkins, L. R., & Maier, S. F. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1161-16.2016 · Cited by 139

The Relationship between Apoptosis and High-Mobility Group Protein 1 Release from Murine Macrophages Stimulated with Lipopolysaccharide or Polyinosinic-Polycytidylic Acid

Jiang, W., Bell, C. W., & Pisetsky, D. S. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.10.6495 · Cited by 134

The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis

Nuovo, G. J., Hagood, J. S., Magro, C. M., Chin, N., Kapil, R., Davis, L., Marsh, C. B., & Folcik, V. A. (2012) · Modern Pathology · doi:10.1038/modpathol.2011.166 · Cited by 123

Principles of inflammasome priming and inhibition: implications for psychiatric disorders

Herman, F. J., & Pasinetti, G. M. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.06.010 · Cited by 115

YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

Tanaka, H., Homma, H., Fujita, K., Kondo, K., Yamada, S., Jin, X., Waragai, M., Ohtomo, G., Iwata, A., Tagawa, K., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-14353-6 · Cited by 119

Kaempferol Attenuates LPS-Induced Striatum Injury in Mice Involving Anti-Neuroinflammation, Maintaining BBB Integrity, and Down-Regulating the HMGB1/TLR4 Pathway

Yang, Y.-L., Cheng, X., Li, W.-H., Liu, M., Wang, Y.-H., & Du, G.-H. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030491 · Cited by 116

A Janus Tale of Two Active High Mobility Group Box 1 (HMGB1) Redox States

Tang, D., Billiar, T. R., & Lotze, M. T. (2012) · Molecular Medicine · doi:10.2119/molmed.2012.00314 · Cited by 112

Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing

White, R. R., Milholland, B., de Bruin, A., Curran, S., Laberge, R.-M., van Steeg, H., Campisi, J., Maslov, A. Y., & Vijg, J. (2015) · Nature Communications · doi:10.1038/ncomms7790 · Cited by 107

Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity

Zhang, C., Feng, J., Du, J., Zhuo, Z., Yang, S., Zhang, W., Wang, W., Zhang, S., Iwakura, Y., Meng, G., et al. (2018) · Cellular & Molecular Immunology · doi:10.1038/cmi.2017.22 · Cited by 99

HMGB1 is a bone‐active cytokine

Yang, J., Shah, R., Robling, A. G., Templeton, E., Yang, H., Tracey, K. J., & Bidwell, J. P. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21268 · Cited by 97

The novel inflammatory cytokine high mobility group box protein 1 (HMGB1) is expressed by human term placenta

Holmlund, U., Wähämaa, H., Bachmayer, N., Bremme, K., Sverremark‐Ekström, E., & Palmblad, K. (2007) · Immunology · doi:10.1111/j.1365-2567.2007.02662.x · Cited by 83

Hmgb1 participates in LPS-induced acute lung injury by activating the aim2 inflammasome in macrophages and inducing polarization of m1 macrophages via TLR2, TLR4, and RAGE/NF-κB signaling pathways

Wang, J., Li, R., Peng, Z., Hu, B., Rao, X., & Li, J. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4402 · Cited by 78

Increased serum HMGB1 is related to the severity of coronary artery stenosis

Hu, X., Jiang, H., Bai, Q., Zhou, X., Xu, C., Lu, Z., Cui, B., & Wen, H. (2009) · Clinica Chimica Acta · doi:10.1016/j.cca.2009.06.016 · Cited by 75

Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity

Teismann, P., Sathe, K., Bierhaus, A., Leng, L., Martin, H. L., Bucala, R., Weigle, B., Nawroth, P. P., & Schulz, J. B. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.12.006 · Cited by 75

Cryptococcus neoformans Promotes Its Transmigration into the Central Nervous System by Inducing Molecular and Cellular Changes in Brain Endothelial Cells

Vu, K., Eigenheer, R. A., Phinney, B. S., & Gelli, A. (2013) · Infection and Immunity · doi:10.1128/iai.00554-13 · Cited by 73

JAK2 inhibition prevents innate immune responses and rescues animals from sepsis

Peña, G., Cai, B., Deitch, E. A., & Ulloa, L. (2010) · Journal of Molecular Medicine · doi:10.1007/s00109-010-0628-z · Cited by 69

ATP/P2X7-NLRP3 axis of dendritic cells participates in the regulation of airway inflammation and hyper-responsiveness in asthma by mediating HMGB1 expression and secretion

Li, R., Wang, J., Li, R., Zhu, F., Xu, W., Zha, G., He, G., Cao, H., Wang, Y., & Yang, J. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.03.002 · Cited by 68

The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer

Feng, A., Tu, Z., & Yin, B. (2016) · Oncotarget · doi:10.18632/oncotarget.7050 · Cited by 57

Targeting HMGB1 TLR4 signaling as a novel approach to treatment of cerebral ischemia

Yang, Q.-W. (2010) · Frontiers in Bioscience · doi:10.2741/s119 · Cited by 55

Stratification of paracetamol overdose patients using new toxicity biomarkers: current candidates and future challenges

Dear, J. W., & Antoine, D. J. (2014) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2014.880650 · Cited by 34

1,25-Dihydroxyvitamin D inhibits LPS-induced high-mobility group box 1 (HMGB1) secretion via targeting the NF-E2-Related factor 2-hemeoxygenase-1-HMGB1 pathway in macrophages

Rao, Z., Zhang, N., Xu, N., Pan, Y., Xiao, M., Wu, J., Zhou, H., Yang, S., & Chen, Y. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01308 · Cited by 27

Expression of HMGB1 in maternal exposure to fine particulate air pollution induces lung injury in rat offspring assessed with micro-CT

Tang, W., Huang, S., Du, L., Sun, W., Yu, Z., Zhou, Y., Chen, J., Li, X., Li, X., Yu, B., et al. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2017.12.016 · Cited by 26

Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy

Kamiya, M., Kimura, N., Umezawa, N., Hasegawa, H., & Yasuda, S. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1191815 · Cited by 21

Expression analysis of HMGB 1 in histological samples of malignant pleural mesothelioma

Rrapaj, E., Trisolini, E., Bertero, L., Salvo, M., Indellicato, R., Andorno, S., Garcia‐Manteiga, J. M., Rena, O., & Boldorini, R. L. (2018) · Histopathology · doi:10.1111/his.13470 · Cited by 17

Treatment of Acute Liver Injury through Selective Tropism of High Mobility Group Box 1 Gene-Silenced Large Peritoneal Macrophages

Oza, D., Ivich, F., Deprey, K., Bittner, K., Bailey, K., Goldman, S., Yu, M., Niedre, M., Tu, H.-C., & Amiji, M. M. (2025) · ACS Nano · doi:10.1021/acsnano.4c18345 · Cited by 9

Levels of serum high mobility group box 1 were independently associated with cardiovascular risk in patients undergoing coronary angiography

Wang, J.-S., Sheu, W. H.-H., Lee, W.-J., Lee, I.-T., Lin, S.-Y., Lee, W.-L., Liang, K.-W., & Lin, S.-J. (2018) · Clinica Chimica Acta · doi:10.1016/j.cca.2018.04.032 · Cited by 5