Fetal liver development and implications for liver disease pathogenesis

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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

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Vascularized and functional human liver from an iPSC-derived organ bud transplant

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Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing

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Endothelial and perivascular cells maintain haematopoietic stem cells

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Resolving the fibrotic niche of human liver cirrhosis at single-cell level

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Exploring tissue architecture using spatial transcriptomics

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SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data

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Pioneer transcription factors: establishing competence for gene expression

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Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

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Definitive Hematopoiesis Is Autonomously Initiated by the AGM Region

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Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

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Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

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Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

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Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in Vivo

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A human liver cell atlas reveals heterogeneity and epithelial progenitors

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Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis

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Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

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Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17–secreting T cells

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A single-cell molecular map of mouse gastrulation and early organogenesis

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Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

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Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

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Liver regeneration: biological and pathological mechanisms and implications

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Biliary atresia

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Role of Kupffer cells in host defense and liver disease

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Liver Organogenesis Promoted by Endothelial Cells Prior to Vascular Function

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Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

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Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

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Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

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Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

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NOTCH2 Mutations Cause Alagille Syndrome, a Heterogeneous Disorder of the Notch Signaling Pathway

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Multipotent Flk-1+ Cardiovascular Progenitor Cells Give Rise to the Cardiomyocyte, Endothelial, and Vascular Smooth Muscle Lineages

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Initiation of Mammalian Liver Development from Endoderm by Fibroblast Growth Factors

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The Liver Sieve: Considerations Concerning the Structure and Function of Endothelial Fenestrae, the Sinusoidal Wall and the Space of Disse

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Fate tracing reveals the endothelial origin of hematopoietic stem cells

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Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

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An electron microscopic study of the fenestrated endothelial lining of rat liver sinusoids

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Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): Review of 80 cases

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Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endodermPreprint

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Decoding human fetal liver haematopoiesis

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Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.Preprint

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Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculaturePreprint

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The initiation of liver development is dependent on Foxa transcription factors

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Immunomodulation by endothelial cells — partnering up with the immune system?

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Global Epidemiology of Chronic Liver Disease

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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids

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Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes

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Cholangiocarcinomas can originate from hepatocytes in mice

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Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth

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Deciphering human macrophage development at single-cell resolution

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Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

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Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

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Spatial heterogeneity in the mammalian liver

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Robust cellular reprogramming occurs spontaneously during liver regeneration

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Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling

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Reversal of Left-Right Asymmetry: a Situs Inversus Mutation

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Mammalian hepatocyte differentiation requires the transcription factor HNF-4αPreprint

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Expansion of hematopoietic stem cells in the developing liver of a mouse embryo

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Notch signaling controls liver development by regulating biliary differentiation

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Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

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Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation

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Two distinct endothelial lineages in ontogeny, one of them related to hemopoiesis

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Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis

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Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations

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ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

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Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells

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The Endoderm of the Mouse Embryo Arises by Dynamic Widespread Intercalation of Embryonic and Extraembryonic Lineages

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The role of TGFβ1 in initiating hepatic stellate cell activation in vivo

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The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation

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The emergent landscape of the mouse gut endoderm at single-cell resolution

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Hepatocyte migration during liver development requires Prox1

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Orchestrating liver development

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Long-Term Hematopoietic Stem Cells Require Stromal Cell-Derived Factor-1 for Colonizing Bone Marrow during Ontogeny

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Paired-cell sequencing enables spatial gene expression mapping of liver endothelial cells

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The onecut transcription factor HNF6 is required for normal development of the biliary tract

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Control of liver cell fate decision by a gradient of TGFβ signaling modulated by Onecut transcription factorsPreprint

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Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

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Liver Progenitor Cells Yield Functional Hepatocytes in Response to Chronic Liver Injury in Mice

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Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1β

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The Human Liver Contains Multiple Populations of NK Cells, T Cells, and CD3+CD56+ Natural T Cells with Distinct Cytotoxic Activities and Th1, Th2, and Th0 Cytokine Secretion Patterns

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Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

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Hepatocytes Do Not Undergo Epithelial-Mesenchymal Transition in Liver Fibrosis in Mice

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Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins

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Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary

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