Cognitive computational neuroscience
Open accessAbstract
To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models that decompose cognition into functional components. Computational neuroscience has modeled how interacting neurons can implement elementary components of cognition. It is time to assemble the pieces of the puzzle of brain computation and to better integrate these separate disciplines. Modern technologies enable us to measure and manipulate brain activity in unprecedentedly rich ways in animals and humans. However, experiments will yield theoretical insight only when employed to test brain-computational models. Here we review recent work in the intersection of cognitive science, computational neuroscience and artificial intelligence. Computational models that mimic brain information processing during perceptual, cognitive and control tasks are beginning to be developed and tested with brain and behavioral data. The authors review recent work at the intersection of cognitive science, computational neuroscience and artificial intelligence that develops and tests computational models mimicking neural and cognitive function during a wide range of tasks.
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Written from the paper’s full text.
TL;DR
The paper argues that understanding cognition requires task-performing computational models tested with brain and behavioral data, integrating cognitive science, computational neuroscience, and artificial intelligence into a “cognitive computational neuroscience.” It reviews bottom-up and top-down modeling approaches and calls for closer integration across Marr’s levels.
Key findings
- Bottom-up models—connectivity/dynamics, decoding, and representational models—can constrain theory but generally do not perform the cognitive tasks in question and thus do not fully explain computational mechanisms.
- Deep convolutional neural network models trained for object classification currently provide the best models of visual representations in inferior temporal cortex in humans and monkeys; higher layers better match later ventral-stream representations, and such models typically have millions of parameters.
- Cognitive models—production systems, reinforcement learning (model-free, model-based, episodic control), and Bayesian models—decompose higher cognition into functional components; Bayesian nonparametric models can explain single-example concept formation, but current inference algorithms require large amounts of computation and do not yet scale to real-world challenges.
- The brain combines statistical and computational efficiency on a 20-watt power budget in ways beyond current AI, motivating integration of Bayesian inference with neural network models.
Methods
- Design: review/perspective article synthesizing recent work at the intersection of cognitive science, computational neuroscience, and artificial intelligence.
- Data or sample: no primary empirical sample; the paper reviews prior computational models, brain-activity studies, and behavioral findings.
- Main analysis: conceptual synthesis organized into “from experiment toward theory” (connectivity, decoding, representational models) and “from theory to experiment” (neural network and cognitive models), with discussion of Marr’s levels and open-science collaboration.
Limitations
- The paper states that current neural network models abstract from neurobiology (for example, action potentials), cognitive models are often implementation-independent, relating Bayesian inference and learning to brain implementation remains challenging, and current Bayesian inference algorithms do not scale to real-world concept formation.
- Evident from the text: as a review, it presents no new experiments or quantitative meta-analysis, and its proposed integration remains programmatic, requiring collaborations and shared components across disciplines.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
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Cites
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Claims the paper makes
0 of 62 cited sources checked · 0 supported · 0 flagged
- Premisecitation
With the advent of human functional brain imaging, scientists began to relate cognitive theories to the human brain.
“With the advent of human functional brain imaging, scientists began to relate cognitive theories to the human brain.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [7] Gazzaniga, M. S. ed. The Cognitive Neurosciences (MIT Press, Cambridge, MA, USA, 2004).
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- Premisereasoning
Cognitive science and cognitive neuroscience parted ways in the 1990s.
“As a result, cognitive science and cognitive neuroscience parted ways in the 1990s.”
Quote in the paperSubstantial claim - Interpretationreasoning
Task-performing computational models that explain how cognition arises from neurobiologically plausible dynamic components will be central to a new cognitive computational neuroscience.
“Here we argue that task-performing computational models that explain how cognition arises from neurobiologically plausible dynamic components will be central to a new cognitive computational neuroscience.”
Quote in the paperNot a substantial claim - Premisecitation
Computational neuroscience has modeled how interacting neurons can implement elementary components of cognition.
“Computational neuroscience has modeled how interacting neurons can implement elementary components of cognition.”
- Also stated in: § Abstract · plain
“In the past two decades, the field developed mathematical models of elementary computational components and their implementation with biological neurons27,28.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [27] Dayan, P. & Abbott, L. F. Theoretical Neuroscience: Computational and Mathematical Modeling of Neural Systems (MIT Press, Cambridge, MA, USA, 2001).
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- cites [28] Abbott, L. F. Theoretical neuroscience rising. Neuron 60, 489–495 (2008). source
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- Also stated in: § Abstract · plain
- Interpretationreasoning
Experiments will yield theoretical insight only when employed to test brain-computational models.
“However, experiments will yield theoretical insight only when employed to test brain-computational models.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Newell, A. You can’t play 20 questions with nature and win: projective comments on the papers of this symposium. Technical Report, School of Computer Science, Carnegie Mellon University (1973). source
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- Premisecitation
Cognitive science has developed task-performing computational models that decompose cognition into functional components.
“Cognitive science has developed computational models that decompose cognition into functional components.”
- Also stated in: § Abstract · plain
“In the 1980s, cognitive science made important advances with symbolic cognitive architectures4,5 and neural networks6, using human behavioral data to adjudicate between candidate computational models.”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [4] Simon, H. A. & Newell, A. Human problem solving: the state of the theory in 1970. Am. Psychol. 26, 145–159 (1971). source
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- cites [5] Anderson, J. R. The Architecture of Cognition (Harvard Univ. Press, Cambridge, MA, USA, 1983).
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- cites [6] McClelland, J. L. & Rumelhart, D. E. Parallel Distributed Processing (MIT Press, Cambridge, MA, USA, 1987). source
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- Also stated in: § Abstract · plain
- Premisecitation
Only synthesis in a computer simulation can reveal what the interaction of proposed component mechanisms entails and whether it can account for the cognitive function in question.
“Only synthesis in a computer simulation can reveal what the interaction of the proposed component mechanisms actually entails and whether it can account for the cognitive function in question.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Newell, A. You can’t play 20 questions with nature and win: projective comments on the papers of this symposium. Technical Report, School of Computer Science, Carnegie Mellon University (1973). source
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- Interpretationnone given
A brain map, at whatever scale, does not reveal the computational mechanism.
“A brain map, at whatever scale, does not reveal the computational mechanism (Fig. 1).”
Quote in the paperNot a substantial claim - Interpretationcitation
Understanding brain information processing requires building computational models capable of performing cognitive tasks.
“Understanding brain information processing requires that we build computational models that are capable of performing cognitive tasks.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Newell, A. You can’t play 20 questions with nature and win: projective comments on the papers of this symposium. Technical Report, School of Computer Science, Carnegie Mellon University (1973). source
Not checked in the free run.
- Premisecitation
Computational models that mimic brain information processing during perceptual, cognitive and control tasks are beginning to be developed and tested with brain and behavioral data.
“Computational models that mimic brain information processing during perceptual, cognitive and control tasks are beginning to be developed and tested with brain and behavioral data.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [37] Kriegeskorte, N. Deep neural networks: a new framework for modeling biological vision and brain information processing. Annu. Rev. Vis. Sci. 1, 417–446 (2015). source
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- cites [38] Yamins, D. L. K. & DiCarlo, J. J. Using goal-driven deep learning models to understand sensory cortex. Nat. Neurosci. 19, 356–365 (2016). source
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- Premisecitation
Computational neuroscience has developed mathematical models of elementary computational components including sensory coding, normalization, working memory, evidence accumulation and decision mechanisms, and motor control.
“These include components for sensory coding29,30, normalization31, working memory32, evidence accumulation and decision mechanisms33–35, and motor control36.”
Quote in the paperSubstantial claim0 of 4 sources checked- cites [29] Olshausen, B. A. & Field, D. J. Sparse coding of sensory inputs. Curr. Opin. Neurobiol. 14, 481–487 (2004). source
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- cites [30] Simoncelli, E. P. & Olshausen, B. A. Natural image statistics and neural representation. Annu. Rev. Neurosci. 24, 1193–1216 (2001). source
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- cites [31] Carandini, M. & Heeger, D. J. Normalization as a canonical neural computation. Nat. Rev. Neurosci. 13, 51–62 (2011). source
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- cites [32] Chaudhuri, R. & Fiete, I. Computational principles of memory. Nat. Neurosci. 19, 394–403 (2016). source
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- Premisecitation
The way anatomical connectivity generates functional connectivity is better modeled by taking local dynamics, delays, indirect interactions and noise into account.
“However, the way anatomical connectivity generates functional connectivity is better modeled by taking local dynamics, delays, indirect interactions and noise into account49.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [49] Deco, G., Jirsa, V. K. & McIntosh, A. R. Emerging concepts for the dynamical organization of resting-state activity in the brain. Nat. Rev. Neurosci. 12, 43–56 (2011). source
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- Premisecitation
Many findings of cognitive neuroscience provide a solid basis on which to build.
“Despite methodological challenges10–11, many of the findings of cognitive neuroscience provide a solid basis on which to build.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [10] Szucs, D. & Ioannidis, J. P. A. Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature. PLoS Biol. 15, e2000797 (2017). source
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- cites [11] Kriegeskorte, N., Simmons, W. K., Bellgowan, P. S. F. & Baker, C. I. Circular analysis in systems neuroscience: the dangers of double dipping. Nat. Neurosci. 12, 535–540 (2009). source
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- Premisecitation
Cognitive neuroscience has mapped the global functional layout of the human and nonhuman primate brain.
“Cognitive neuroscience has mapped the global functional layout of the human and nonhuman primate brain20.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [20] Van Essen, D. C. et al. The Brain Analysis Library of Spatial maps and Atlases (BALSA) database. Neuroimage 144(Pt. B), 270–274 (2017). source
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- Premisecitation
Some of the most important recent advances in AI are driven by deep neural network models composed of units that compute linear combinations of their inputs followed by static nonlinearities.
“Some of the most important recent advances are driven by deep neural network models, composed of units that compute linear combinations of their inputs, followed by static nonlinearities42.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [42] LeCun, Y., Bengio, Y. & Hinton, G. Deep learning. Nature 521, 436–444 (2015). source
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- Interpretationreasoning
Cognitive neuroscience has not achieved a full computational account of brain information processing.
“However, it has not achieved a full computational account of brain information processing.”
Quote in the paperSubstantial claim - Premisereasoning
The topology and geometry of a biological neural network constrain its dynamics, and thus its functional mechanism.
“More generally, the topology and geometry of a biological neural network constrain its dynamics, and thus its functional mechanism.”
Quote in the paperSubstantial claim - Interpretationreasoning
AI, and in particular machine learning, is a key discipline that provides the theoretical and technological foundation for cognitive computational neuroscience.
“AI, and in particular machine learning, is therefore a key discipline that provides the theoretical and technological foundation for cognitive computational neuroscience.”
Quote in the paperSubstantial claim - Premisecitation
Findings of face-selective regions in the human ventral stream have been thoroughly replicated and generalized.
“For example, the findings of face-selective regions in the human ventral stream12 have been thoroughly replicated and generalized.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [12] Kanwisher, N., McDermott, J. & Chun, M. M. The fusiform face area: a module in human extrastriate cortex specialized for face perception. J. Neurosci. 17, 4302–4311 (1997). source
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- Interpretationreasoning
Functional localization results, especially in combination with anatomical connectivity, may ultimately prove useful for modeling brain information processing.
“Functional localization results, especially in combination with anatomical connectivity, may therefore ultimately prove useful for modeling brain information processing.”
Quote in the paperNot a substantial claim - Premisecitation
Bayesian models have begun to engage complex cognition, including the way our minds model the physical and social world.
“Initially applied to basic sensory and motor processes23,24, Bayesian models have begun to engage complex cognition, including the way our minds model the physical and social world2.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [2] Lake, B. M., Ullman, T. D., Tenenbaum, J. B. & Gershman, S. J. Building machines that learn and think like people. Behav. Brain Sci. 40, e253 (2017). source
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- Interpretationreasoning
Mapping provides constraints for theory.
“However, mapping does provide constraints for theory.”
Quote in the paperSubstantial claim - Interpretationreasoning
Component placement is likely to reflect these costs.
“Component placement is likely to reflect these costs.”
Quote in the paperSubstantial claim - Premisecitation
Computational neuroscience has begun to test complex computational models that can explain high-level sensory and cognitive brain representations.
“Computational neuroscience has also begun to test complex computational models that can explain high-level sensory and cognitive brain representations37,38.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [37] Kriegeskorte, N. Deep neural networks: a new framework for modeling biological vision and brain information processing. Annu. Rev. Vis. Sci. 1, 417–446 (2015). source
Not checked in the free run.
- cites [38] Yamins, D. L. K. & DiCarlo, J. J. Using goal-driven deep learning models to understand sensory cortex. Nat. Neurosci. 19, 356–365 (2016). source
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- Premisecitation
Neuronal dynamics can be measured and modeled at multiple scales, from local sets of interacting neurons to whole-brain activity.
“Neuronal dynamics can be measured and modeled at multiple scales, from local sets of interacting neurons to whole-brain activity45.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [45] Deco, G., Tononi, G., Boly, M. & Kringelbach, M. L. Rethinking segregation and integration: contributions of whole-brain modelling. Nat. Rev. Neurosci. 16, 430–439 (2015). source
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- Interpretationreasoning
The three disciplines contribute complementary elements to biologically plausible computational models that perform cognitive tasks and explain brain information processing and behavior.
“The three disciplines contribute complementary elements to biologically plausible computational models that perform cognitive tasks and explain brain information processing and behavior (Fig. 2).”
Quote in the paperSubstantial claim - Premisecitation
Bayesian cognitive models optimally combine prior knowledge about the world with sensory evidence.
“One success story is that of Bayesian cognitive models, which optimally combine prior knowledge about the world with sensory evidence21–23.”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [21] Griffiths, T. L., Chater, N., Kemp, C., Perfors, A. & Tenenbaum, J. B. Probabilistic models of cognition: exploring representations and inductive biases. Trends Cogn. Sci. 14, 357–364 (2010). source
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- cites [22] Ernst, M. O. & Banks, M. S. Humans integrate visual and haptic information in a statistically optimal fashion. Nature 415, 429–433 (2002). source
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- cites [23] Weiss, Y., Simoncelli, E. P. & Adelson, E. H. Motion illusions as optimal percepts. Nat. Neurosci. 5, 598–604 (2002). source
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- Interpretationreasoning
Regions that need to interact at high bandwidth and short latency are expected to be placed close together.
“We expect regions that need to interact at high bandwidth and short latency to be placed close together9.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] Chklovskii, D. B. & Koulakov, A. A. Maps in the brain: what can we learn from them? Annu. Rev. Neurosci. 27, 369–392 (2004). source
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- Interpretationreasoning
Effective connectivity and large-scale brain dynamics analyses do not capture the represented information and how it is processed in the brain.
“However, they do not capture the represented information and how it is processed in the brain.”
Quote in the paperSubstantial claim - Premisecitation
Cognitive experiments have revealed signatures of sampling and amortized inference in human behavior.
“In particular, cognitive experiments have revealed signatures of sampling111 and amortized inference112 in human behavior.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [111] Sanborn, A. N. & Chater, N. Bayesian brains without probabilities. Trends Cogn. Sci. 20, 883–893 (2016). source
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- cites [112] Dasgupta, I., Schulz, E., Goodman, N. & Gershman, S. Amortized hypothesis generation. Preprint at bioRxiv https://doi.org/10.1101/137190 (2017). source
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- Premisecitation
By declaring their models independent of the implementation in the brain, cognitive scientists are able to address high-level cognitive processes that are beyond the reach of current neural networks.
“By declaring their models independent of the implementation in the brain, cognitive scientists are able to address high-level cognitive processes21,97,98 that are beyond the reach of current neural networks.”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [21] Griffiths, T. L., Chater, N., Kemp, C., Perfors, A. & Tenenbaum, J. B. Probabilistic models of cognition: exploring representations and inductive biases. Trends Cogn. Sci. 14, 357–364 (2010). source
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- cites [97] Fiser, J., Berkes, P., Orbán, G. & Lengyel, M. Statistically optimal perception and learning: from behavior to neural representations. Trends Cogn. Sci. 14, 119–130 (2010). source
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- cites [98] Tenenbaum, J. B., Kemp, C., Griffiths, T. L. & Goodman, N. D. How to grow a mind: statistics, structure, and abstraction. Science 331, 1279–1285 (2011). source
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- Premisereasoning
An agent attempting to learn a generative model can mine all its experiences for insights on its environment and itself without external supervision or reinforcement.
“It does not require external supervision or reinforcement to learn, but can mine all its experiences for insights on its environment and itself.”
Quote in the paperSubstantial claim - Interpretationreasoning
All three disciplines converge on the algorithms and representations of the brain and mind, contributing complementary constraints.
“All three disciplines thus converge on the algorithms and representations of the brain and mind, contributing complementary constraints116.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [116] Love, B. C. The algorithmic level is the bridge between computation and brain. Top. Cogn. Sci. 7, 230–242 (2015). source
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- Premisecitation
Bayesian nonparametric models may explain the brain's statistical efficiency, its ability to infer much from little data by building generative models that provide abstract prior knowledge.
“They may explain the brain’s stunning statistical efficiency, its ability to infer so much from so little data by building generative models that provide abstract prior knowledge98.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [98] Tenenbaum, J. B., Kemp, C., Griffiths, T. L. & Goodman, N. D. How to grow a mind: statistics, structure, and abstraction. Science 331, 1279–1285 (2011). source
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- Interpretationreasoning
The approximations the brain makes for computational efficiency may explain human deviations from statistical optimality.
“Moreover, the corners cut by the brain for computational efficiency, the approximations, may explain human deviations from statistical optimality.”
Quote in the paperSubstantial claim - Premisecitation
Relating Bayesian inference and learning, especially structure learning in nonparametric models, to its implementation in the brain remains challenging.
“However, relating Bayesian inference and learning, especially structure learning in nonparametric models, to its implementation in the brain remains challenging107.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [107] Tervo, D. G. R., Tenenbaum, J. B. & Gershman, S. J. Toward the neural implementation of structure learning. Curr. Opin. Neurobiol. 37, 99–105 (2016). source
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- Premisecitation
Approximate inference algorithms such as sampling may explain cortical feedback signals and activity correlations.
“As theories of brain computation, approximate inference algorithms such as sampling may explain cortical feedback signals and activity correlations97,108–110.”
Quote in the paperSubstantial claim0 of 4 sources checked- cites [97] Fiser, J., Berkes, P., Orbán, G. & Lengyel, M. Statistically optimal perception and learning: from behavior to neural representations. Trends Cogn. Sci. 14, 119–130 (2010). source
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- Premisecitation
Decoding and other types of multivariate pattern analysis have helped reveal the content of regional representations, providing evidence that brain-computational models must incorporate.
“Decoding and other types of multivariate pattern analysis have helped reveal the content of regional representations55,56,58,59, providing evidence that brain-computational models must incorporate.”
Quote in the paperSubstantial claim0 of 4 sources checked- cites [55] Norman, K. A., Polyn, S. M., Detre, G. J. & Haxby, J. V. Beyond mind-reading: multi-voxel pattern analysis of fMRI data. Trends Cogn. Sci. 10, 424–430 (2006). source
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- Premisecitation
The representation of probability distributions in neuronal populations has been explored theoretically and experimentally.
“The representation of probability distributions in neuronal populations has been explored theoretically and experimentally105,106.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [105] Pouget, A., Beck, J. M., Ma, W. J. & Latham, P. E. Probabilistic brains: knowns and unknowns. Nat. Neurosci. 16, 1170–1178 (2013). source
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- cites [106] Orhan, A. E. & Ma, W. J. Efficient probabilistic inference in generic neural networks trained with non-probabilistic feedback. Nat. Commun. 8, 138 (2017). source
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- Premisecitation
Deep neural network models can explain the computationally efficient pattern recognition component.
“They can explain the computationally efficient pattern recognition component42.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [42] LeCun, Y., Bengio, Y. & Hinton, G. Deep learning. Nature 521, 436–444 (2015). source
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- Interpretationreasoning
Generative models are an essential ingredient of general intelligence.
“Generative models are an essential ingredient of general intelligence.”
Quote in the paperNot a substantial claim - Premisenone given
Even in computer science, certain aspects of algorithms depend on the hardware, such as its parallel processing capabilities.
“Even in computer science, however, certain aspects of the algorithms depend on the hardware, such as its parallel processing capabilities.”
Quote in the paperSubstantial claim - Interpretationreasoning
Brains differ from computers in ways that exacerbate the dependence of algorithms on hardware.
“Brains differ from computers in ways that exacerbate this dependence.”
Quote in the paperSubstantial claim
- Classified as probably not a substantial claim. 27
- May combine two claims. 12
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Premisenone givenThe transition from cognitive psychology to cognitive science was defined by the introduction of task-performing computational models.
“In the spirit of Newell’s critique, the transition from cognitive psychology to cognitive science was defined by the introduction of task-performing computational models.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Premisenone givenComputer hardware and machine learning were not sufficiently advanced to simulate cognitive processes in their full complexity.
“However, computer hardware and machine learning were not sufficiently advanced to simulate cognitive processes in their full complexity.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationcitationIf we had a full understanding of an information-processing mechanism, we should be able to engineer it.
“If we did have a full understanding of an information-processing mechanism, then we should be able to engineer it.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
PremisecitationHypothesis testing needed to be complemented by the construction of comprehensive task-performing computational models.
“Hypothesis testing, in his view, needed to be complemented by the construction of comprehensive task-performing computational models.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Newell, A. You can’t play 20 questions with nature and win: projective comments on the papers of this symposium. Technical Report, School of Computer Science, Carnegie Mellon University (1973). source
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Classified as probably not a substantial claim. May combine two claims.
Premisenone givenEarly cognitive science developments relied on behavioral data alone and did not leverage constraints provided by the anatomy and activity of the brain.
“Moreover, these early developments relied on behavioral data alone and did not leverage constraints provided by the anatomy and activity of the brain.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S1 (asserted).
PremisecitationTesting verbally defined hypotheses about cognition might never lead to a computational understanding.
“Newell argued that testing verbally defined hypotheses about cognition might never lead to a computational understanding.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Newell, A. You can’t play 20 questions with nature and win: projective comments on the papers of this symposium. Technical Report, School of Computer Science, Carnegie Mellon University (1973). source
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Classified as probably not a substantial claim.
InterpretationreasoningA brain-computational model of face recognition will have to explain the spatial clusters of face-selective units and the selectivities and invariances observed with fMRI and invasive recordings.
“A brain-computational model of face recognition16 will have to explain the spatial clusters of face-selective units and the selectivities and invariances observed with fMRI17,18 and invasive recordings14,19.”
Quote in the paperSubstantial claim0 of 5 sources checked- cites [16] Yildirim, I. et al. Efficient and robust analysis-by-synthesis in vision: a computational framework, behavioral tests, and modeling neuronal representations. in Annual Conference of the Cognitive Science Society (eds. Noelle, D. C. et al.) (Cognitive Science Society, Austin, TX, USA, 2015).
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- cites [17] Kriegeskorte, N., Formisano, E., Sorger, B. & Goebel, R. Individual faces elicit distinct response patterns in human anterior temporal cortex. Proc. Natl Acad. Sci. USA 104, 20600–20605 (2007). source
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- cites [18] Anzellotti, S., Fairhall, S. L. & Caramazza, A. Decoding representations of face identity that are tolerant to rotation. Cereb. Cortex 24, 1988–1995 (2014). source
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- cites [14] Freiwald, W. A. & Tsao, D. Y. Functional compartmentalization and viewpoint generalization within the macaque face-processing system. Science 330, 845–851 (2010). source
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- cites [19] Chang, L. & Tsao, D. Y. The code for facial identity in the primate brain. Cell 169, 1013–1028.e14 (2017). source
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May combine two claims.
PremisecitationPrimate face patches revealed high densities of face-selective neurons, with invariances emerging at higher stages of hierarchical processing.
“Localized with fMRI and probed with invasive electrode recordings, the primate face patches revealed high densities of face-selective neurons13, with invariances emerging at higher stages of hierarchical processing, including mirror-symmetric tuning and view-tolerant representations of individual faces in the anteriormost patch14.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [13] Tsao, D. Y., Freiwald, W. A., Tootell, R. B. & Livingstone, M. S. A cortical region consisting entirely of face-selective cells. Science 311, 670–674 (2006). source
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- cites [14] Freiwald, W. A. & Tsao, D. Y. Functional compartmentalization and viewpoint generalization within the macaque face-processing system. Science 330, 845–851 (2010). source
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Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationreasoningDeep neural network models' functionality is inspired by brains and could be implemented with biological neurons.
“However, their functionality is inspired by brains and could be implemented with biological neurons.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationRecent advances in machine learning, boosted by growing computational power and larger datasets, have brought progress at perceptual, cognitive and control challenges.
“Recent advances in machine learning, boosted by growing computational power and larger datasets from which to learn, have brought progress at perceptual39, cognitive40 and control challenges41.”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [39] Krizhevsky, A., Sutskever, I. & Hinton, G. E. ImageNet classification with deep convolutional neural networks. in Advances in Neural Information Processing Systems 25 1097–1105 (Curran Associates, Red Hook, NY, USA, 2012).
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- cites [40] Silver, D. et al. Mastering the game of Go with deep neural networks and tree search. Nature 529, 484–489 (2016). source
Not checked in the free run.
- cites [41] Mnih, V. et al. Human-level control through deep reinforcement learning. Nature 518, 529–533 (2015). source
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable), S4 (based).
Interpretationnone givenIf computational models are to explain animal and human cognition, they will have to perform feats of intelligence.
“If computational models are to explain animal and human cognition, they will have to perform feats of intelligence.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationThe face perception literature shows solid progress in mapping the anatomical substrate and characterizing neuronal responses but lacks definitive computational models.
“The example of face perception illustrates, on one hand, the solid progress in mapping the anatomical substrate and characterizing neuronal responses15 and, on the other, the lack of definitive computational models.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15] Grill-Spector, K., Weiner, K. S., Kay, K. & Gomez, J. The functional neuroanatomy of human face perception. Annu. Rev. Vis. Sci. 3, 167–196 (2017). source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenDeep neural network models employ only a small subset of the dynamic capabilities of biological neurons, abstracting from fundamental features such as action potentials.
“These models employ only a small subset of the dynamic capabilities of biological neurons, abstracting from fundamental features such as action potentials.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationnone givenMost component functions in computational neuroscience are computationally simple but provide building blocks for cognition.
“Most of these component functions are computationally simple, but they provide building blocks for cognition.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
PremisereasoningThe anatomical connectivity matrix typically resembles the functional connectivity matrix because regions interact through anatomical pathways.
“The anatomical connectivity matrix typically resembles the functional connectivity matrix because regions interact through anatomical pathways.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Premisenone givenConnectivity models go beyond the localization of activated regions and characterize the interactions between regions.
“Connectivity models go beyond the localization of activated regions and characterize the interactions between regions.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Premisenone givenInformation exchange incurs costs that scale with the distance between communicating regions-costs in physical connections, energy and signal latency.
“After all, information exchange incurs costs that scale with the distance between the communicating regions—costs in terms of physical connections, energy and signal latency.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningConnectivity models, decoding models, and representational models provide constraints for computational theory but do not in general perform cognitive tasks and thus fall short of explaining the computational mechanism underlying task performance.
“The models employed in this literature provide constraints for computational theory, but they do not in general perform the cognitive tasks in question and thus fall short of explaining the computational mechanism underlying task performance.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable).
Premisenone givenCognitive models decompose cognition into meaningful functional components.
“Cognitive models, including the three classes highlighted here, decompose cognition into meaningful functional components.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
PremisereasoningIt is always in the context of prior theory (generative models of the observed processes) that better observations advance our understanding.
“However, it is always in the context of prior theory (generative models of the observed processes) that better observations advance our understanding.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
Interpretationnone givenWhen particular content is decodable from activity in a brain region, this indicates the presence of the information.
“When particular content is decodable from activity in a brain region, this indicates the presence of the information.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
InterpretationreasoningDeep neural network models provide a biologically plausible account of the rapid recognition of the elements of the visual experience.
“Deep neural network models provide a biologically plausible account of the rapid recognition of the elements of the visual experience (people, steps, oblique upward motion, handrail).”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationMarr (1982) offered a distinction of three levels of analysis: computational theory, representation and algorithm, and neurobiological implementation.
“Marr (1982) offered a distinction of three levels of analysis: (i) computational theory, (ii) representation and algorithm, and (iii) neurobiological implementation115.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [115] Marr, D. Vision: A Computational Investigation into the Human Representation and Processing of Visual Information (MIT Press, Cambridge, MA, USA, 2010). source
Not checked in the free run.
May combine two claims.
PremisereasoningDeep neural network models cannot yet explain how a child understands relationships among elements, physical interactions, goals, function of an escalator, or how she can imagine the experience and instantly form a new concept.
“However, they cannot explain yet how the child understands the relationships among the elements, the physical interactions of the objects, the people’s goal to go up, and the function of the escalator, or how she can imagine the experience and instantly form a new concept.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Premisenone givenAI builds representations and algorithms that combine simple components to implement complex feats of intelligence.
“AI builds representations and algorithms that combine simple components to implement complex feats of intelligence.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningIt may not be possible to understand cognition without considering its implementation in the brain or to make sense of neuronal circuits except in the context of the cognitive functions they support.
“It may therefore not be possible to understand cognition without considering its implementation in the brain or, conversely, to make sense of neuronal circuits except in the context of the cognitive functions they support.”
Quote in the paperNot a substantial claim- Rests on an assumption: Brains are the product of evolution and development, processes that are not constrained to generate systems whose behavior can be perfectly captured at some abstract level of description.
Probably not a substantial claim: may not pass S4 (based). May combine two claims.
PremisereasoningCurrent inference algorithms require large amounts of computation and do not yet scale to real-world challenges such as forming the new concept "escalator" from a single visual experience.
“However, current inference algorithms require large amounts of computation and, as a result, do not yet scale to real-world challenges such as forming the new concept “escalator” from a single visual experience.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenComputational neuroscience proceeds from the bottom up, composing neuronal building blocks into representations and algorithms thought to be useful components in the context of the brain's overall function.
“Computational neuroscience proceeds from the bottom up, composing neuronal building blocks into representations and algorithms thought to be useful components in the context of the brain’s overall function.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Premisenone givenCognitive science starts from computational theory, decomposing cognition into components and developing representations and algorithms from the top down.
“Cognitive science starts from computational theory, decomposing cognition into components and developing representations and algorithms from the top down.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningCognitive models are essential for cognitive computational neuroscience because they enable us to see the whole as we attempt to understand the roles of the parts.
“Cognitive models are essential for cognitive computational neuroscience because they enable us to see the whole as we attempt to understand the roles of the parts.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningThe ability to decode particular information does not amount to a full account of the neuronal code: it does not specify the representational format or what other information might additionally be present.
“However, the ability to decode particular information does not amount to a full account of the neuronal code: it doesn’t specify the representational format (beyond linear decodability) or what other information might additionally be present.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningThis enables engineers to abstract from the circuits when designing algorithms.
“This enables the engineers to abstract from the circuits when designing the algorithms.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S4 (based).
PremisereasoningCausal models of processes in the world can give an agent a deeper understanding and thus a better basis for inferences and actions.
“In particular, causal models of processes in the world (how objects cause images, how the present causes the future) can give an agent a deeper understanding and thus a better basis for inferences and actions.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
InterpretationreasoningBayesian nonparametric models explain how deep inferences and concept formation from single experiences are even possible.
“Bayesian nonparametric models explain how deep inferences and concept formation from single experiences are even possible.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
Modern technologies enable us to measure and manipulate brain activity in unprecedentedly rich ways in animals and humans.
“Modern technologies enable us to measure and manipulate brain activity in unprecedentedly rich ways in animals and humans.”
The paper relies on this without support.
Biological organisms have limited time to learn and limited memory, and must avoid interactions that might kill them.
“Biological organisms, however, have limited time to learn and limited memory, and must avoid interactions that might kill them.”
The paper relies on this without support.
The brain seamlessly merges bottom-up discriminative and top-down generative computations in perceptual inference, and model-free and model-based control.
“The brain seamlessly merges bottom-up discriminative and top-down generative computations in perceptual inference, and model-free and model-based control.”
The paper relies on this without support.
Brains are the product of evolution and development, processes that are not constrained to generate systems whose behavior can be perfectly captured at some abstract level of description.
“Brains are the product of evolution and development, processes that are not constrained to generate systems whose behavior can be perfectly captured at some abstract level of description.”
The paper relies on this without support.
On a 20-watt power budget, the brain’s algorithms combine statistical and computational efficiency in ways that are beyond current AI of either the Bayesian or the neural network variety.
“On a 20-watt power budget, the brain’s algorithms combine statistical and computational efficiency in ways that are beyond current AI of either the Bayesian or the neural network variety.”
The paper relies on this without support.
Recent advances in computer hardware and software enable AI-scale modeling of the mind and brain.
“Recent advances in computer hardware and software enable AI-scale modeling of the mind and brain.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The mathematical formalism of Bayesian approaches has particular appeal in an era when neuroscience increasingly values computational sophistication.
“The mathematical formalism of Bayesian approaches has particular appeal in an era when neuroscience increasingly values computational sophistication (Kriegeskorte and Douglas 2018).”
From The myth of the Bayesian brain (2025) · cites this paper as Kriegeskorte and Douglas 2018
Formal artificial intelligence models provide flexibility in planning and account for a range of biological processes at neural and behavioural levels.
“Formal artificial intelligence models provide flexibility in planning and account for a range of biological processes at neural and behavioural levels 204 .”
From From cognitive maps to spatial schemas (2023) · cites this paper as [204]
Navigation planning follows a hierarchical representation of space that consists of a series of contexts that, in humans, is mediated by the dorsomedial PFC.
“Studies of navigation support the idea that navigation planning follows a hierarchical representation of space that consist of a series of contexts that, in humans, is mediated by the dorsomedial PFC 128,133,159,204 .”
From From cognitive maps to spatial schemas (2023) · cites this paper as [204]
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Flagged first, then by citations
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“The mathematical formalism of Bayesian approaches has particular appeal in an era when neuroscience increasingly values computational sophistication (Kriegeskorte and Douglas 2018).”
State and capacity in neural models of cognition and consciousness
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- Authors
- Kriegeskorte, N., & Douglas, P. K.
- Affiliations
- Mortimer B. Zuckerman Mind Brain Behavior Institute (US)
- University of California, Los Angeles (US)
- Corresponding author
- Kriegeskorte, Nikolaus
- Venue
- Nature Neuroscience
- Published
- 2018-08-20
- Volume
- 21
- Issue
- 9
- Pages
- 1148-1160
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- PMC
- PMC6706072
- OpenAlex
- W2887972576
- Semantic Scholar
- fe65133015723d49f8090e0aec099e7b61b8a54b
- Cited by
- 535
- References
- 151
- Citations by year
- 2026: 54 · 2025: 69 · 2024: 89 · 2023: 69 · 2022: 100 · 2021: 62 · 2020: 53 · 2019: 37 · 2018: 2
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (K01MH110645)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Physical Sciences › Computer Science › Artificial Intelligence › Cognitive Computing and Networks
- Keywords
- cognitive modeling, artificial intelligence, neural information processing, perceptual tasks, cognitive control
- MeSH terms
- Animals, Cognition, Computer Simulation, Humans, Models, Neurological, Neurosciences, Computational Biology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-09.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-09.
Statistics and arithmetic are recomputed, not judged.
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