Development and future of droplet microfluidics

In situ click chemistry generation of cyclooxygenase-2 inhibitors

Bhardwaj, A., Kaur, J., Wuest, M., & Wuest, F. (2017) · Nature Communications · doi:10.1038/s41467-016-0009-6 · Cited by 7,448

Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets.

Macosko, E. Z., Basu, A., Satija, R., Nemesh, J., Shekhar, K., Goldman, M., Tirosh, I., Bialas, A. R., Kamitaki, N., Martersteck, E. M., et al. (2015) · Cell · doi:10.1016/j.cell.2015.05.002 · Cited by 7,110

Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells

Klein, A. M., Mazutis, L., Akartuna, I., Tallapragada, N., Veres, A., Li, V., Peshkin, L., Weitz, D. A., & Kirschner, M. W. (2015) · Cell · doi:10.1016/j.cell.2015.04.044 · Cited by 3,356

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

Hindson, B. J., Ness, K. D., Masquelier, D. A., Belgrader, P., Heredia, N. J., Makarewicz, A. J., Bright, I. J., Lucero, M. Y., Hiddessen, A. L., Legler, T. C., et al. (2011) · Analytical Chemistry · doi:10.1021/ac202028g · Cited by 2,792

Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up

Garstecki, P., Fuerstman, M. J., Stone, H. A., & Whitesides, G. M. (2006) · Lab on a Chip · doi:10.1039/b510841a · Cited by 2,339

Soft lithography for micro- and nanoscale patterning

Qin, D., Xia, Y., & Whitesides, G. M. (2010) · Nature Protocols · doi:10.1038/nprot.2009.234 · Cited by 2,334

Formation of dispersions using “flow focusing” in microchannels

Anna, S. L., Bontoux, N., & Stone, H. A. (2003) · Applied Physics Letters · doi:10.1063/1.1537519 · Cited by 2,302

Monodisperse Double Emulsions Generated from a Microcapillary Device

Utada, A. S., Lorenceau, E., Link, D. R., Kaplan, P. D., Stone, H. A., & Weitz, D. A. (2005) · Science · doi:10.1126/science.1109164 · Cited by 2,248

Microfluidic Large-Scale Integration

Thorsen, T., Maerkl, S. J., & Quake, S. R. (2002) · Science · doi:10.1126/science.1076996 · Cited by 2,222

Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device

Thorsen, T., Roberts, R. W., Arnold, F. H., & Quake, S. R. (2001) · Physical Review Letters · doi:10.1103/physrevlett.86.4163 · Cited by 2,051

Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits

Cho, S. K., Moon, H., & Kim, C.-J. (2003) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2002.807467 · Cited by 1,598

Emerging Droplet Microfluidics

Shang, L., Cheng, Y., & Zhao, Y. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00848 · Cited by 1,584

Control and detection of chemical reactions in microfluidic systems

deMello, A. J. (2006) · Nature · doi:10.1038/nature05062 · Cited by 1,495

Absolute quantification by droplet digital PCR versus analog real-time PCR

Hindson, C. M., Chevillet, J. R., Briggs, H. A., Gallichotte, E. N., Ruf, I. K., Hindson, B. J., Vessella, R. L., & Tewari, M. (2013) · Nature Methods · doi:10.1038/nmeth.2633 · Cited by 1,488

Single-cell analysis and sorting using droplet-based microfluidics

Mazutis, L., Gilbert, J., Ung, W. L., Weitz, D. A., Griffiths, A. D., & Heyman, J. A. (2013) · Nature Protocols · doi:10.1038/nprot.2013.046 · Cited by 1,355

Geometrically Mediated Breakup of Drops in Microfluidic Devices

Link, D. R., Anna, S. L., Weitz, D. A., & Stone, H. A. (2004) · Physical Review Letters · doi:10.1103/physrevlett.92.054503 · Cited by 1,202

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

Agresti, J. J., Antipov, E., Abate, A. R., Ahn, K., Rowat, A. C., Baret, J.-C., Marquez, M., Klibanov, A. M., Griffiths, A. D., & Weitz, D. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910781107 · Cited by 1,149

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

Kang, H. M., Subramaniam, M., Targ, S., Nguyen, M., Maliskova, L., McCarthy, E., Wan, E., Wong, S., Byrnes, L., Lanata, C. M., et al. (2018) · Nature Biotechnology · doi:10.1038/nbt.4042 · Cited by 1,101

A Microfluidic System for Controlling Reaction Networks in Time

Song, H., Tice, J. D., & Ismagilov, R. F. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200390203 · Cited by 1,082

Droplet microfluidic technology for single-cell high-throughput screening

Brouzes, E., Medkova, M., Savenelli, N., Marran, D., Twardowski, M., Hutchison, J. B., Rothberg, J. M., Link, D. R., Perrimon, N., & Samuels, M. L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903542106 · Cited by 1,069

Controlled microfluidic interfaces

Atencia, J., & Beebe, D. J. (2005) · Nature · doi:10.1038/nature04163 · Cited by 1,006

Dripping to Jetting Transitions in Coflowing Liquid Streams

Utada, A. S., Fernandez-Nieves, A., Stone, H. A., & Weitz, D. A. (2007) · Physical Review Letters · doi:10.1103/physrevlett.99.094502 · Cited by 965

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

Baret, J.-C., Miller, O. J., Taly, V., Ryckelynck, M., El-Harrak, A., Frenz, L., Rick, C., Samuels, M. L., Hutchison, J. B., Agresti, J. J., et al. (2009) · Lab on a Chip · doi:10.1039/b902504a · Cited by 951

Microfluidic methods for generating continuous droplet streams

Christopher, G. F., & Anna, S. L. (2007) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/40/19/r01 · Cited by 860

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

Rotem, A., Ram, O., Shoresh, N., Sperling, R. A., Goren, A., Weitz, D. A., & Bernstein, B. E. (2015) · Nature Biotechnology · doi:10.1038/nbt.3383 · Cited by 854

Generation of Monodisperse Particles by Using Microfluidics: Control over Size, Shape, and Composition

Xu, S., Nie, Z., Seo, M., Lewis, P., Kumacheva, E., Stone, H. A., Garstecki, P., Weibel, D. B., Gitlin, I., & Whitesides, G. M. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200462226 · Cited by 830

Controllable Monodisperse Multiple Emulsions

Chu, L., Utada, A. S., Shah, R. K., Kim, J., & Weitz, D. A. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200701358 · Cited by 747

Transition from squeezing to dripping in a microfluidic T-shaped junction

DE MENECH, M., GARSTECKI, P., JOUSSE, F., & STONE, H. A. (2008) · Journal of Fluid Mechanics · doi:10.1017/s002211200700910x · Cited by 728

Single-cell barcoding and sequencing using droplet microfluidics

Zilionis, R., Nainys, J., Veres, A., Savova, V., Zemmour, D., Klein, A. M., & Mazutis, L. (2017) · Nature Protocols · doi:10.1038/nprot.2016.154 · Cited by 727

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

Clausell-Tormos, J., Lieber, D., Baret, J.-C., El-Harrak, A., Miller, O. J., Frenz, L., Blouwolff, J., Humphry, K. J., Köster, S., Duan, H., et al. (2008) · Chemistry & Biology · doi:10.1016/j.chembiol.2008.04.004 · Cited by 720

Monodisperse Emulsion Generation via Drop Break Off in a Coflowing Stream

Umbanhowar, P. B., Prasad, V., & Weitz, D. A. (2000) · Langmuir · doi:10.1021/la990101e · Cited by 693

Preparation of Monodisperse Biodegradable Polymer Microparticles Using a Microfluidic Flow‐Focusing Device for Controlled Drug Delivery

Xu, Q., Hashimoto, M., Dang, T. T., Hoare, T., Kohane, D. S., Whitesides, G. M., Langer, R., & Anderson, D. G. (2009) · Small · doi:10.1002/smll.200801855 · Cited by 602

Monodisperse Alginate Hydrogel Microbeads for Cell Encapsulation

Tan, W. ‐., & Takeuchi, S. (2007) · Advanced Materials · doi:10.1002/adma.200700433 · Cited by 599

Enhancing computational fluid dynamics with machine learning

Vinuesa, R., & Brunton, S. L. (2022) · Nature Computational Science · doi:10.1038/s43588-022-00264-7 · Cited by 596

Perfectly Monodisperse Microbubbling by Capillary Flow Focusing

Gañán-Calvo, A. M., & Gordillo, J. M. (2001) · Physical Review Letters · doi:10.1103/physrevlett.87.274501 · Cited by 587

Interfacial synthesis of hollow metal–organic framework capsules demonstrating selective permeability

Ameloot, R., Vermoortele, F., Vanhove, W., Roeffaers, M. B. J., Sels, B. F., & De Vos, D. E. (2011) · Nature Chemistry · doi:10.1038/nchem.1026 · Cited by 574

Drop formation in a co-flowing ambient fluid

Cramer, C., Fischer, P., & Windhab, E. J. (2004) · Chemical Engineering Science · doi:10.1016/j.ces.2004.04.006 · Cited by 538

Drop-based microfluidic devices for encapsulation of single cells

Köster, S., Angilè, F. E., Duan, H., Agresti, J. J., Wintner, A., Schmitz, C., Rowat, A. C., Merten, C. A., Pisignano, D., Griffiths, A. D., et al. (2008) · Lab on a Chip · doi:10.1039/b802941e · Cited by 518

Design of microfluidic channel geometries for the control of droplet volume, chemical concentration, and sorting

Tan, Y.-C., Fisher, J. S., Lee, A. I., Cristini, V., & Lee, A. P. (2004) · Lab on a Chip · doi:10.1039/b403280m · Cited by 509

High-throughput injection with microfluidics using picoinjectors

Abate, A. R., Hung, T., Mary, P., Agresti, J. J., & Weitz, D. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1006888107 · Cited by 502

Rapid droplet mixers for digital microfluidic systems

Paik, P., Pamula, V. K., & Fair, R. B. (2003) · Lab Chip · doi:10.1039/b307628h · Cited by 497

High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer

Grosselin, K., Durand, A., Marsolier, J., Poitou, A., Marangoni, E., Nemati, F., Dahmani, A., Lameiras, S., Reyal, F., Frenoy, O., et al. (2019) · Nature Genetics · doi:10.1038/s41588-019-0424-9 · Cited by 466

One-Step Fabrication of Supramolecular Microcapsules from Microfluidic Droplets

Zhang, J., Coulston, R. J., Jones, S. T., Geng, J., Scherman, O. A., & Abell, C. (2012) · Science · doi:10.1126/science.1215416 · Cited by 456

Microdroplet-based PCR enrichment for large-scale targeted sequencing

Tewhey, R., Warner, J. B., Nakano, M., Libby, B., Medkova, M., David, P. H., Kotsopoulos, S. K., Samuels, M. L., Hutchison, J. B., Larson, J. W., et al. (2009) · Nature Biotechnology · doi:10.1038/nbt.1583 · Cited by 454

ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens

Suo, T., Liu, X., Feng, J., Guo, M., Hu, W., Guo, D., Ullah, H., Yang, Y., Zhang, Q., Wang, X., et al. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1772678 · Cited by 450

Microfluidic Fabrication of Monodisperse Biocompatible and Biodegradable Polymersomes with Controlled Permeability

Shum, H. C., Kim, J.-W., & Weitz, D. A. (2008) · Journal of the American Chemical Society · doi:10.1021/ja802157y · Cited by 445

Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding

Lan, F., Demaree, B., Ahmed, N., & Abate, A. R. (2017) · Nature Biotechnology · doi:10.1038/nbt.3880 · Cited by 431

Injectable Stem Cell‐Laden Photocrosslinkable Microspheres Fabricated Using Microfluidics for Rapid Generation of Osteogenic Tissue Constructs

Zhao, X., Liu, S., Yildirimer, L., Zhao, H., Ding, R., Wang, H., Cui, W., & Weitz, D. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201504943 · Cited by 426

Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets

Bringer, M. R., Gerdts, C. J., Song, H., Tice, J. D., & Ismagilov, R. F. (2004) · Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2003.1364 · Cited by 416

Decompressing Emulsion Droplets Favors Coalescence

Bremond, N., Thiam, A. R., & Bibette, J. (2008) · Physical Review Letters · doi:10.1103/physrevlett.100.024501 · Cited by 413

Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring

Wang, B., Zhao, C., Wang, Z., Yang, K.-A., Cheng, X., Liu, W., Yu, W., Lin, S., Zhao, Y., Cheung, K. M., et al. (2022) · Science Advances · doi:10.1126/sciadv.abk0967 · Cited by 403

Emerging aqueous two-phase systems: from fundamentals of interfaces to biomedical applications

Chao, Y., & Shum, H. C. (2020) · Chemical Society Reviews · doi:10.1039/c9cs00466a · Cited by 397

Droplet Control for Microfluidics

Joanicot, M., & Ajdari, A. (2005) · Science · doi:10.1126/science.1112615 · Cited by 379

Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery

Mao, A. S., Shin, J.-W., Utech, S., Wang, H., Uzun, O., Li, W., Cooper, M., Hu, Y., Zhang, L., Weitz, D. A., et al. (2017) · Nature Materials · doi:10.1038/nmat4781 · Cited by 371

Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices

Franke, T., Abate, A. R., Weitz, D. A., & Wixforth, A. (2009) · Lab on a Chip · doi:10.1039/b906819h · Cited by 369

Microfluidic Generation of Monodisperse, Structurally Homogeneous Alginate Microgels for Cell Encapsulation and 3D Cell Culture

Utech, S., Prodanovic, R., Mao, A. S., Ostafe, R., Mooney, D. J., & Weitz, D. A. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201500021 · Cited by 366

Double Emulsion Templated Monodisperse Phospholipid Vesicles

Shum, H. C., Lee, D., Yoon, I., Kodger, T., & Weitz, D. A. (2008) · Langmuir · doi:10.1021/la801833a · Cited by 362

Dripping, Jetting, Drops, and Wetting: The Magic of Microfluidics

Utada, A. S., Chu, L.-Y., Fernandez-Nieves, A., Link, D. R., Holtze, C., & Weitz, D. A. (2007) · MRS Bulletin · doi:10.1557/mrs2007.145 · Cited by 358

Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays

Huebner, A., Bratton, D., Whyte, G., Yang, M., deMello, A. J., Abell, C., & Hollfelder, F. (2009) · Lab Chip · doi:10.1039/b813709a · Cited by 346

Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells

Chabert, M., & Viovy, J.-L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708321105 · Cited by 344

Somatic mutations and cell identity linked by Genotyping of Transcriptomes

Nam, A. S., Kim, K.-T., Chaligne, R., Izzo, F., Ang, C., Taylor, J., Myers, R. M., Abu-Zeinah, G., Brand, R., Omans, N. D., et al. (2019) · Nature · doi:10.1038/s41586-019-1367-0 · Cited by 333

Microfluidic high-throughput culturing of single cells for selection based on extracellular metabolite production or consumption

Wang, B. L., Ghaderi, A., Zhou, H., Agresti, J., Weitz, D. A., Fink, G. R., & Stephanopoulos, G. (2014) · Nature Biotechnology · doi:10.1038/nbt.2857 · Cited by 330

Electrowetting-based droplet mixers for microfluidic systemsElectronic supplementary information (ESI) available: six mpeg videos showing some mixing schemes used in Fig. 7. See http://www.rsc.org/suppdata/lc/b2/b210825a/

Paik, P., Pamula, V. K., Pollack, M. G., & Fair, R. B. (2003) · Lab on a Chip · doi:10.1039/b210825a · Cited by 327

Droplet-based microfluidics

Moragues, T., Arguijo, D., Beneyton, T., Modavi, C., Simutis, K., Abate, A. R., Baret, J.-C., deMello, A. J., Densmore, D., & Griffiths, A. D. (2023) · Nature Reviews Methods Primers · doi:10.1038/s43586-023-00212-3 · Cited by 316

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

Setliff, I., Shiakolas, A. R., Pilewski, K. A., Murji, A. A., Mapengo, R. E., Janowska, K., Richardson, S., Oosthuysen, C., Raju, N., Ronsard, L., et al. (2019) · Cell · doi:10.1016/j.cell.2019.11.003 · Cited by 314

Droplet‐Based Microreactors for the Synthesis of Magnetic Iron Oxide Nanoparticles

Frenz, L., El Harrak, A., Pauly, M., Bégin‐Colin, S., Griffiths, A. D., & Baret, J. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200801360 · Cited by 313

Droplet formation and breakup dynamics in microfluidic flow-focusing devices: From dripping to jetting

Fu, T., Wu, Y., Ma, Y., & Li, H. Z. (2012) · Chemical Engineering Science · doi:10.1016/j.ces.2012.08.039 · Cited by 312

High‐Order Multiple Emulsions Formed in Poly(dimethylsiloxane) Microfluidics

Abate, A. R., & Weitz, D. A. (2009) · Small · doi:10.1002/smll.200900569 · Cited by 311

Discrete elements for 3D microfluidics

Bhargava, K. C., Thompson, B., & Malmstadt, N. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1414764111 · Cited by 298

High-performance flow-focusing geometry for spontaneous generation of monodispersed droplets

Yobas, L., Martens, S., Ong, W.-L., & Ranganathan, N. (2006) · Lab on a Chip · doi:10.1039/b602240e · Cited by 293

Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states

Ma, P., Amemiya, H. M., He, L. L., Gandhi, S. J., Nicol, R., Bhattacharyya, R. P., Smillie, C. S., & Hung, D. T. (2023) · Cell · doi:10.1016/j.cell.2023.01.002 · Cited by 291

High-resolution dose–response screening using droplet-based microfluidics

Miller, O. J., Harrak, A. E., Mangeat, T., Baret, J.-C., Frenz, L., Debs, B. E., Mayot, E., Samuels, M. L., Rooney, E. K., Dieu, P., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113324109 · Cited by 286

Barcoded viral tracing of single-cell interactions in central nervous system inflammation

Clark, I. C., Gutiérrez-Vázquez, C., Wheeler, M. A., Li, Z., Rothhammer, V., Linnerbauer, M., Sanmarco, L. M., Guo, L., Blain, M., Zandee, S. E. J., et al. (2021) · Science · doi:10.1126/science.abf1230 · Cited by 285

High-throughput, single-microbe genomics with strain resolution, applied to a human gut microbiome

Zheng, W., Zhao, S., Yin, Y., Zhang, H., Needham, D. M., Evans, E. D., Dai, C. L., Lu, P. J., Alm, E. J., & Weitz, D. A. (2022) · Science · doi:10.1126/science.abm1483 · Cited by 283

Multicompartment Polymersomes from Double Emulsions

Shum, H. C., Zhao, Y., Kim, S., & Weitz, D. A. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201006023 · Cited by 280

Functional single-cell hybridoma screening using droplet-based microfluidics

Debs, B. E., Utharala, R., Balyasnikova, I. V., Griffiths, A. D., & Merten, C. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1204514109 · Cited by 276

Sorting drops and cells with acoustics: acoustic microfluidic fluorescence-activated cell sorter

Schmid, L., Weitz, D. A., & Franke, T. (2014) · Lab Chip · doi:10.1039/c4lc00588k · Cited by 271

Single Molecule Protein Detection with Attomolar Sensitivity Using Droplet Digital Enzyme-Linked Immunosorbent Assay

Cohen, L., Cui, N., Cai, Y., Garden, P. M., Li, X., Weitz, D. A., & Walt, D. R. (2020) · ACS Nano · doi:10.1021/acsnano.0c02378 · Cited by 263

Double-emulsion drops with ultra-thin shells for capsule templates

Kim, S.-H., Kim, J. W., Cho, J.-C., & Weitz, D. A. (2011) · Lab Chip · doi:10.1039/c1lc20434c · Cited by 259

Reverse transcriptase droplet digital PCR shows high resilience to PCR inhibitors from plant, soil and water samples

Rački, N., Dreo, T., Gutierrez-Aguirre, I., Blejec, A., & Ravnikar, M. (2014) · Plant Methods · doi:10.1186/s13007-014-0042-6 · Cited by 257

High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics

Gérard, A., Woolfe, A., Mottet, G., Reichen, M., Castrillon, C., Menrath, V., Ellouze, S., Poitou, A., Doineau, R., Briseno-Roa, L., et al. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-0466-7 · Cited by 256

Microfluidic Formation of Monodisperse Coacervate Organelles in Liposomes

Deng, N., & Huck, W. T. S. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201703145 · Cited by 247

A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities

Leung, K., Zahn, H., Leaver, T., Konwar, K. M., Hanson, N. W., Pagé, A. P., Lo, C.-C., Chain, P. S., Hallam, S. J., & Hansen, C. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106752109 · Cited by 243

Controllable microfluidic production of multicomponent multiple emulsions

Wang, W., Xie, R., Ju, X.-J., Luo, T., Liu, L., Weitz, D. A., & Chu, L.-Y. (2011) · Lab on a Chip · doi:10.1039/c1lc20065h · Cited by 232

Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

Bauer, W.-A. C., Fischlechner, M., Abell, C., & Huck, W. T. S. (2010) · Lab on a Chip · doi:10.1039/c004046k · Cited by 227

Robust scalable high throughput production of monodisperse drops

Amstad, E., Chemama, M., Eggersdorfer, M., Arriaga, L. R., Brenner, M. P., & Weitz, D. A. (2016) · Lab on a Chip · doi:10.1039/c6lc01075j · Cited by 227

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity

Terekhov, S. S., Smirnov, I. V., Stepanova, A. V., Bobik, T. V., Mokrushina, Y. A., Ponomarenko, N. A., Belogurov, A. A., Rubtsova, M. P., Kartseva, O. V., Gomzikova, M. O., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1621226114 · Cited by 223

Accurate microfluidic sorting of droplets at 30 kHz

Sciambi, A., & Abate, A. R. (2015) · Lab on a Chip · doi:10.1039/c4lc01194e · Cited by 215

Smart Microgel Capsules from Macromolecular Precursors

Seiffert, S., Thiele, J., Abate, A. R., & Weitz, D. A. (2010) · Journal of the American Chemical Society · doi:10.1021/ja102156h · Cited by 206

Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme

Mazutis, L., Baret, J.-C., Treacy, P., Skhiri, Y., Araghi, A. F., Ryckelynck, M., Taly, V., & Griffiths, A. D. (2009) · Lab on a Chip · doi:10.1039/b907753g · Cited by 205

Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells

Cole, R. H., Tang, S.-Y., Siltanen, C. A., Shahi, P., Zhang, J. Q., Poust, S., Gartner, Z. J., & Abate, A. R. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704020114 · Cited by 204

A microdroplet dilutor for high-throughput screening

Niu, X., Gielen, F., Edel, J. B., & deMello, A. J. (2011) · Nature Chemistry · doi:10.1038/nchem.1046 · Cited by 199

Biodegradable Core–Shell Carriers for Simultaneous Encapsulation of Synergistic Actives

Windbergs, M., Zhao, Y., Heyman, J., & Weitz, D. A. (2013) · Journal of the American Chemical Society · doi:10.1021/ja401422r · Cited by 199

Controlled multistep synthesis in a three-phase droplet reactor

Nightingale, A. M., Phillips, T. W., Bannock, J. H., & de Mello, J. C. (2014) · Nature Communications · doi:10.1038/ncomms4777 · Cited by 195

Mobile platform for rapid sub–picogram-per-milliliter, multiplexed, digital droplet detection of proteins

Yelleswarapu, V., Buser, J. R., Haber, M., Baron, J., Inapuri, E., & Issadore, D. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1814110116 · Cited by 185

High-volume production of single and compound emulsions in a microfluidic parallelization arrangement coupled with coaxial annular world-to-chip interfaces

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Future foods: Design, fabrication and production through microfluidics

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