Robotic touch shifts perception of embodiment to a prosthesis in targeted reinnervation amputees
Open accessAbstract
Existing prosthetic limbs do not provide amputees with cutaneous feedback. Tactile feedback is essential to intuitive control of a prosthetic limb and it is now clear that the sense of body self-identification is also linked to cutaneous touch. Here we have created an artificial sense of touch for a prosthetic limb by coupling a pressure sensor on the hand through a robotic stimulator to surgically redirected cutaneous sensory nerves (targeted reinnervation) that once served the lost limb. We hypothesize that providing physiologically relevant cutaneous touch feedback may help an amputee incorporate an artificial limb into his or her self image. To investigate this we used a robotic touch interface coupled with a prosthetic limb and tested it with two targeted reinnervation amputees in a series of experiments fashioned after the Rubber Hand Illusion. Results from both subjective (self-reported) and objective (physiological) measures of embodiment (questionnaires, psychophysical temporal order judgements and residual limb temperature measurements) indicate that returning physiologically appropriate cutaneous feedback from a prosthetic limb drives a perceptual shift towards embodiment of the device for these amputees. Measurements provide evidence that the illusion created is vivid. We suggest that this may help amputees to more effectively incorporate an artificial limb into their self image, providing the possibility that a prosthesis becomes not only a tool, but also an integrated body part.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Sensory perception is important for control of the prosthetic limb, a sense of embodiment, and in the reduction of phantom limb pain.
“Sensory perception is important for control of the prosthetic limb, a sense of embodiment (3), and in the reduction of phantom limb pain (4, 5).”
From A neural interface provides long-term stable natural touch perception (2014) · cites this paper as [3]
Embodiment may help amputees think of the prosthesis as a body part rather than just a tool.
“Embodiment may help amputees think of the prosthesis as a body part rather than just a tool (Marasco et al., 2011).”
From Biomimetic approaches to bionic touch through a peripheral nerve interface (2015) · cites this paper as Marasco et al., 2011
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Rubber hands ‘feel’ touch that eyes see
Botvinick, M., & Cohen, J. (1998) · Nature · doi:10.1038/35784 · Cited by 4,410 · see citing works
Multiple Comparison Procedures
Hochberg, Y., & Tamhane, A. C. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316672 · Cited by 2,389 · see citing works
Multiple Comparison Procedures
Hahs-Vaughn, D., & Lomax, R. (2013) · Routledge eBooks · doi:10.4324/9780203137819-17 · Cited by 2,132 · see citing works
Brain–machine interfaces: past, present and future
Lebedev, M. A., & Nicolelis, M. A. L. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.07.004 · Cited by 1,875 · see citing works
That's my hand! Activity in premotor cortex reflects feeling of ownership of a limb
Ehrsson, H. H., Spence, C., & Passingham, R. E. (2004) · Science · doi:10.1126/science.1097011 · Cited by 1,348 · see citing works
The rubber hand illusion revisited: visuotactile integration and self-attribution
Tsakiris, M., & Haggard, P. (2005) · Journal of Experimental Psychology: Human Perception and Performance · doi:10.1037/0096-1523.31.1.80 · Cited by 1,328 · see citing works
Travis, W. D., Castile, R. G., Vawter, G. F., Shwachman, H., Warwick, W. J., Burke, B. A., & Skinner, M. M. (1986) · American Journal of Clinical Pathology · doi:10.1093/ajcp/85.4.419 · Cited by 1,189 · see citing works
My body in the brain: A neurocognitive model of body-ownership.
Tsakiris, M. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.09.034 · Cited by 1,069 · see citing works
Projecting sensations to external objects: evidence from skin conductance response
Armel, K. C., & Ramachandran, V. S. (2003) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2003.2364 · Cited by 854 · see citing works
Kuiken, T. A., Dumanian, G. A., Lipschutz, R. D., Miller, L. A., & Stubblefield, K. A. (2004) · Prosthetics & Orthotics International · doi:10.3109/03093640409167756 · Cited by 583 · see citing works
Self-citationDirect neural sensory feedback and control of a prosthetic arm
Dhillon, G. S., & Horch, K. W. (2005) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2005.856072 · Cited by 573 · see citing works
On the other hand: Dummy hands and peripersonal space
Makin, T. R., Holmes, N. P., & Ehrsson, H. H. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.02.041 · Cited by 530 · see citing works
Moseley, G. L., Olthof, N., Venema, A., Don, S., Wijers, M., Gallace, A., & Spence, C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803768105 · Cited by 493 · see citing works
Kuiken, T., Miller, L. A., Lipschutz, R. D., Lock, B. A., Stubblefield, K. A., Marasco, P. D., Zhou, P., & Dumanian, G. A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60193-7 · Cited by 477 · see citing works
Self-citationMore than skin deep: Body representation beyond primary somatosensory cortex
Longo, M. R., Azañón, E., & Haggard, P. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.08.022 · Cited by 473 · see citing works
Spence, C. J., Shore, D. I., & Klein, R. M. (2001) · Journal of Experimental Psychology General · doi:10.1037/0096-3445.130.4.799 · Cited by 462 · see citing works
Perceptual Correlates of Massive Cortical Reorganization
Ramachandran, V. S., Rogers-Ramachandran, D., & Stewart, M. (1992) · Science · doi:10.1126/science.1439826 · Cited by 434 · see citing works
Upper limb amputees can be induced to experience a rubber hand as their own
Ehrsson, H. H., Rosén, B., Stockselius, A., Ragnö, C., Kohler, P., & Lundborg, G. (2008) · Brain · doi:10.1093/brain/awn297 · Cited by 343 · see citing works
Perceptual correlates of massive cortical reorganization
Ramachandran, V. S., Stewart, M., & Rogers-Ramachandran, D. (1992) · Neuroreport · doi:10.1097/00001756-199207000-00009 · Cited by 327 · see citing works
Cortical reorganization and phantom phenomena in congenital and traumatic upper-extremity amputees
Flor, H., Elbert, T. R., Mühlnickel, W., Pantev, C., Wienbruch, C., & Taub, E. (1998) · Experimental Brain Research · doi:10.1007/s002210050334 · Cited by 300 · see citing works
Kuiken, T., Marasco, P. D., Lock, B. A., Harden, R. N., & Dewald, J. P. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706525104 · Cited by 284 · see citing works
Self-citationProsthetic usage in major upper extremity amputations
Wright, T. W., Hagen, A. D., & Wood, M. B. (1995) · The Journal Of Hand Surgery · doi:10.1016/s0363-5023(05)80278-3 · Cited by 268 · see citing works
Acute plasticity in the human somatosensory cortex following amputation
Borsook, D., Becerra, L. R., Fishman, S. M., Edwards, A., Jennings, C. L., Stojanovic, M. P., Papinicolas, L., Ramachandran, V. S., González, R. G., & Breiter, H. (1998) · Neuroreport · doi:10.1097/00001756-199804200-00011 · Cited by 229 · see citing works
Decoding a New Neural–Machine Interface for Control of Artificial Limbs
Zhou, P., Lowery, M. M., Englehart, K. B., Huang, H., Li, G., Hargrove, L., Dewald, J. P. A., & Kuiken, T. A. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00178.2007 · Cited by 215 · see citing works
Self-citationNeural Interface Technology for Rehabilitation: Exploiting and Promoting Neuroplasticity
Wang, W., Collinger, J. L., Pérez, M. A., Tyler‐Kabara, E. C., Cohen, L. G., Birbaumer, N., Brose, S. W., Schwartz, A. B., Boninger, M. L., & Weber, D. J. (2009) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2009.07.003 · Cited by 208 · see citing works
Improved Myoelectric Prosthesis Control Accomplished Using Multiple Nerve Transfers
Hijjawi, J. B., Kuiken, T., Lipschutz, R. D., Miller, L. A., Stubblefield, K. A., & Dumanian, G. A. (2006) · Plastic & Reconstructive Surgery · doi:10.1097/01.prs.0000242487.62487.fb · Cited by 157 · see citing works
Self-citationSpatial remapping of touch: Confusion of perceived stimulus order across hand and foot
Heed, T., & Röder, B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601486103 · Cited by 156 · see citing works
Patterson, P. E., & Katz, J. A. (1992) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.1992.01.0001 · Cited by 147 · see citing works
Skin temperature side differences – a diagnostic tool for CRPS?
Wasner, G. L., Schattschneider, J., & Baron, R. (2002) · Pain · doi:10.1016/s0304-3959(01)00470-5 · Cited by 147 · see citing works
Targeted reinnervation for transhumeral amputees: current surgical technique and update on results
Dumanian, G. A., Ko, J. H., O’Shaughnessy, K. D., Kim, P. S., Wilson, C. J., & Kuiken, T. A. (2009) · Plastic and Reconstructive Surgery · doi:10.1097/prs.0b013e3181b038c9 · Cited by 130 · see citing works
Self-citationTargeted Reinnervation to Improve Prosthesis Control in Transhumeral Amputees
O’Shaughnessy, K. D., Dumanian, G. A., Lipschutz, R. D., Miller, L. A., Stubblefield, K. A., & Kuiken, T. (2008) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.g.00268 · Cited by 122 · see citing works
Self-citationThermographic imaging of cutaneous sensory segment in patients with peripheral nerve injury
Uematsu, S. (1985) · Journal of neurosurgery · doi:10.3171/jns.1985.62.5.0716 · Cited by 120 · see citing works
The Development of Brain-Machine Interface Neuroprosthetic Devices
Patil, P. G., & Turner, D. A. (2008) · Neurotherapeutics · doi:10.1016/j.nurt.2007.11.002 · Cited by 118 · see citing works
Sensory capacity of reinnervated skin after redirection of amputated upper limb nerves to the chest
Marasco, P. D., Schultz, A. E., & Kuiken, T. A. (2009) · Brain · doi:10.1093/brain/awp082 · Cited by 113 · see citing works
Self-citationVisual enhancement of touch and the bodily self
Longo, M. R., Cardozo, S., & Haggard, P. (2008) · Consciousness and Cognition · doi:10.1016/j.concog.2008.01.001 · Cited by 110 · see citing works
Validation of Thermography in the Diagnosis of Reflex Sympathetic Dystrophy
Bruehl, S. P., Lubenow, T. R., Nath, H. A., & Ivankovich, O. (1996) · Clinical Journal of Pain · doi:10.1097/00002508-199612000-00011 · Cited by 109 · see citing works
On the Design of Miniature Haptic Devices for Upper Extremity Prosthetics
Kim, K., Colgate, J. E., Santos-Munné, J. J., Makhlin, A. R., & Peshkin, M. A. (2009) · IEEE/ASME Transactions on Mechatronics · doi:10.1109/tmech.2009.2013944 · Cited by 100 · see citing works
Self-citationSensory-feedback system compatible with myoelectric control
Scott, R. N., Brittain, R. H., Caldwell, R. R., Cameron, A. B., & Dunfield, V. A. (1980) · Medical & Biological Engineering & Computing · doi:10.1007/bf02442481 · Cited by 93 · see citing works
A myoelectrically-controlled prosthesis with sensory feedback
Shannon, G. F. (1979) · Medical & Biological Engineering & Computing · doi:10.1007/bf02440956 · Cited by 91 · see citing works
SENSORY SUBSTITUTION IN PROSTHETICS
Lundborg, G., & Rosén, B. (2001) · Hand Clinics · doi:10.1016/s0749-0712(21)00526-6 · Cited by 80 · see citing works
Murray, C. D. (2007) · Psychoprosthetics · doi:10.1007/978-1-84628-980-4_9 · Cited by 79 · see citing works
Functional Restoration of Adults and Children with Upper Extremity Amputation
Meier, R. H., & Atkins, D. J. (2004) · Medical Entomology and Zoology · Cited by 74 · see citing works
Anani, A. B., Ikeda, K., & Körner, L. M. (1977) · Medical & Biological Engineering & Computing · doi:10.1007/bf02457988 · Cited by 74 · see citing works
Welch, R. B. (1972) · Perception & Psychophysics · doi:10.3758/bf03210933 · Cited by 72 · see citing works
A neural substrate for nonpainful phantom limb phenomena
Flor, H., Mühlnickel, W., Karl, A., Denke, C., Grüsser, S. M., Kurth, R., & Taub, E. (2000) · Neuroreport · doi:10.1097/00001756-200005150-00011 · Cited by 69 · see citing works
Schaefer, M., Nöennig, N., Heinze, H., & Rotte, M. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.07.001 · Cited by 65 · see citing works
Schultz, A. E., Marasco, P. D., & Kuiken, T. A. (2009) · Brain Research · doi:10.1016/j.brainres.2008.11.039 · Cited by 58 · see citing works
Self-citationArtificial touch in a hand-prosthesis
Beeker, T. W., During, J., & den Hertog, A. (1967) · Medical & Biological Engineering & Computing · doi:10.1007/bf02478841 · Cited by 55 · see citing works
Feedback in Myoelectric Prostheses
Scott, R. N. (1990) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199007000-00010 · Cited by 46 · see citing works
Sensinger, J. W., Schultz, A. E., & Kuiken, T. (2009) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2009.2032640 · Cited by 38 · see citing works
Self-citationRybarczyk, B. D., & Behel, J. M. (2007) · Springer eBooks · doi:10.1007/978-1-84628-980-4_3 · Cited by 34 · see citing works
Prior, R. E., & Lyman, J. (1975) · PubMed · Cited by 19 · see citing works
Flagged first, then by citations
1 of the 53 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Pursuing prosthetic electronic skin
Chortos, A., Liu, J., & Bao, Z. (2016) · Nature Materials · doi:10.1038/nmat4671 · Cited by 2,396 · see citing works
Multisensory brain mechanisms of bodily self-consciousness.
Blanke, O. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3292 · Cited by 1,147 · see citing works
A neural interface provides long-term stable natural touch perception
Tan, D. W., Schiefer, M. A., Keith, M. W., Anderson, J. R., Tyler, J., & Tyler, D. J. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008669 · Cited by 751 · see citing works
Intracortical microstimulation of human somatosensory cortex
Flesher, S. N., Collinger, J. L., Foldes, S. T., Weiss, J. M., Downey, J. E., Tyler-Kabara, E. C., Bensmaia, S. J., Schwartz, A. B., Boninger, M. L., & Gaunt, R. A. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf8083 · Cited by 704 · see citing works
Sensory feedback in upper limb prosthetics
Antfolk, C., D’Alonzo, M., Rosén, B., Lundborg, G., Sebelius, F., & Cipriani, C. (2013) · Expert Review of Medical Devices · doi:10.1586/erd.12.68 · Cited by 466 · see citing works
Restoring sensorimotor function through intracortical interfaces: progress and looming challenges
Bensmaia, S. J., & Miller, L. E. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3724 · Cited by 368 · see citing works
Valle, G., Mazzoni, A., Iberite, F., D’Anna, E., Strauss, I., Granata, G., Controzzi, M., Clemente, F., Rognini, G., Cipriani, C., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.08.033 · Cited by 340 · see citing works
Restoring the sense of touch with a prosthetic hand through a brain interface
Tabot, G. A., Dammann, J. F., Berg, J. A., Tenore, F. V., Boback, J. L., Vogelstein, R. J., & Bensmaia, S. J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1221113110 · Cited by 320 · see citing works
A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback
D’Anna, E., Valle, G., Mazzoni, A., Strauss, I., Iberite, F., Patton, J., Petrini, F. M., Raspopovic, S., Granata, G., Di Iorio, R., et al. (2019) · Science Robotics · doi:10.1126/scirobotics.aau8892 · Cited by 321 · see citing works
Neurological diseases and pain
Borsook, D. (2011) · Brain · doi:10.1093/brain/awr271 · Cited by 283 · see citing works
The cognitive bases of human tool use
Vaesen, K. (2012) · Behavioral and Brain Sciences · doi:10.1017/s0140525x11001452 · Cited by 279 · see citing works
Toward higher-performance bionic limbs for wider clinical use
Farina, D., Vujaklija, I., Brånemark, R., Bull, A. M. J., Dietl, H., Graimann, B., Hargrove, L. J., Hoffmann, K.-P., Huang, H., Ingvarsson, T., et al. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00732-x · Cited by 263 · see citing works
Self-citationProsthetic Myoelectric Control Strategies: A Clinical Perspective
Roche, A. D., Rehbaum, H., Farina, D., & Aszmann, O. C. (2014) · Current Surgery Reports · doi:10.1007/s40137-013-0044-8 · Cited by 262 · see citing works
Restoration of sensory information via bionic hands
Bensmaı̈a, S. J., Tyler, D. J., & Micera, S. (2020) · Nature Biomedical Engineering · doi:10.1038/s41551-020-00630-8 · Cited by 256 · see citing works
Schiefer, M., Tan, D., Sidek, S. M., & Tyler, D. J. (2016) · Journal of Neural Engineering · doi:10.1088/1741-2560/13/1/016001 · Cited by 255 · see citing works
A Review of Sensory Feedback in Upper-Limb Prostheses From the Perspective of Human Motor Control
Sensinger, J. W., & Dosen, S. S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00345 · Cited by 233 · see citing works
Wendelken, S., Page, D. M., Davis, T., Wark, H. A. C., Kluger, D. T., Duncan, C., Warren, D. J., Hutchinson, D. T., & Clark, G. A. (2017) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-017-0320-4 · Cited by 216 · see citing works
Thermoelectric Polymer Aerogels for Pressure–Temperature Sensing Applications
Han, S., Jiao, F., Khan, Z. U., Edberg, J., Fabiano, S., & Xavier Crispin, A. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201703549 · Cited by 218 · see citing works
Graczyk, E. L., Resnik, L. J., Schiefer, M. A., Schmitt, M. S., & Tyler, D. J. (2018) · Scientific Reports · doi:10.1038/s41598-018-26952-x · Cited by 214 · see citing works
D’Anna, E., Petrini, F. M., Artoni, F., Popovic, I., Igor, S., Raspopović, S., & Micera, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-11306-w · Cited by 215 · see citing works
Neural Basis of Touch and Proprioception in Primate Cortex
Delhaye, B. P., Long, K. H., & Bensmaia, S. J. (2018) · Comprehensive Physiology · doi:10.1002/cphy.c170033 · Cited by 214 · see citing works
Illusory movement perception improves motor control for prosthetic hands
Marasco, P. D., Hebert, J. S., Sensinger, J. W., Shell, C. E., Schofield, J. S., Thumser, Z. C., Nataraj, R., Beckler, D. T., Dawson, M. R. W., Blustein, D. H., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aao6990 · Cited by 200 · see citing works
Self-citationSix‐Month Assessment of a Hand Prosthesis with Intraneural Tactile Feedback
Petrini, F. M., Valle, G., Strauss, I., Granata, G., Di Iorio, R., D'Anna, E., Čvančara, P., Mueller, M., Carpaneto, J., Clemente, F., et al. (2019) · Annals of Neurology · doi:10.1002/ana.25384 · Cited by 195 · see citing works
Horch, K., Meek, S., Taylor, T. G., & Hutchinson, D. T. (2011) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2011.2162635 · Cited by 194 · see citing works
Antfolk, C., D’Alonzo, M., Controzzi, M., Lundborg, G., Rosén, B., Sebelius, F., & Cipriani, C. (2012) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2012.2217989 · Cited by 194 · see citing works
The role of feed-forward and feedback processes for closed-loop prosthesis control
Saunders, I., & Vijayakumar, S. (2011) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-8-60 · Cited by 192 · see citing works
Biomimetic approaches to bionic touch through a peripheral nerve interface
Saal, H. P., & Bensmaia, S. J. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.06.010 · Cited by 179 · see citing works
“Embodiment may help amputees think of the prosthesis as a body part rather than just a tool (Marasco et al., 2011).”
Tan, D. W., Schiefer, M. A., Keith, M. W., Anderson, J. R., & Tyler, D. J. (2015) · Journal of Neural Engineering · doi:10.1088/1741-2560/12/2/026002 · Cited by 175 · see citing works
Page, D. M., George, J. A., Kluger, D. T., Duncan, C. C., Wendelken, S., Davis, T. S., Hutchinson, D. T., & Clark, G. A. (2018) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00352 · Cited by 178 · see citing works
A Miniature Vibrotactile Sensory Substitution Device for Multifingered Hand Prosthetics
Cipriani, C., D’Alonzo, M., & Carrozza, M. C. (2011) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2011.2173342 · Cited by 164 · see citing works
Rognini, G., Petrini, F. M., Raspopović, S., Valle, G., Granata, G., Strauss, I., Solcà, M., Bello‐Ruiz, J., Herbelin, B., Mange, R., et al. (2018) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-318570 · Cited by 148 · see citing works
Marasco, P. D., Hebert, J. S., Sensinger, J. W., Beckler, D. T., Thumser, Z. C., Shehata, A. W., Williams, H. E., & Wilson, K. R. (2021) · Science Robotics · doi:10.1126/scirobotics.abf3368 · Cited by 136 · see citing works
Self-citationChai, G., Sui, X., Li, S., He, L., & Lan, N. (2015) · Journal of Neural Engineering · doi:10.1088/1741-2560/12/6/066002 · Cited by 131 · see citing works
Prosthetic embodiment: systematic review on definitions, measures, and experimental paradigms
Zbinden, J., Lendaro, E., & Ortiz-Catalan, M. (2022) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-022-01006-6 · Cited by 135 · see citing works
Exploring Teleimpedance and Tactile Feedback for Intuitive Control of the Pisa/IIT SoftHand
Ajoudani, A., Godfrey, S. B., Bianchi, M., Catalano, M. G., Grioli, G., Tsagarakis, N. G., & Bicchi, A. (2014) · IEEE Transactions on Haptics · doi:10.1109/toh.2014.2309142 · Cited by 128 · see citing works
The embodiment of assistive devices—from wheelchair to exoskeleton
Pazzaglia, M., & Molinari, M. (2015) · Physics of Life Reviews · doi:10.1016/j.plrev.2015.11.006 · Cited by 130 · see citing works
Sensory restoration by epidural stimulation of the lateral spinal cord in upper-limb amputees
Chandrasekaran, S., Nanivadekar, A. C., McKernan, G., Helm, E. R., Boninger, M. L., Collinger, J. L., Gaunt, R. A., & Fisher, L. E. (2020) · eLife · doi:10.7554/elife.54349 · Cited by 108 · see citing works
Forearm amputees' views of prosthesis use and sensory feedback
Wijk, U., & Carlsson, I. (2015) · Journal of Hand Therapy · doi:10.1016/j.jht.2015.01.013 · Cited by 114 · see citing works
Antfolk, C., Björkman, A., Frank, S., Sebelius, F., Lundborg, G., & Rosén, B. (2012) · Journal of Rehabilitation Medicine · doi:10.2340/16501977-1001 · Cited by 113 · see citing works
Current Solutions and Future Trends for Robotic Prosthetic Hands
Mendez, V., Iberite, F., Shokur, S., & Micera, S. (2021) · Annual Review of Control Robotics and Autonomous Systems · doi:10.1146/annurev-control-071020-104336 · Cited by 112 · see citing works
Perceiving invisible light through a somatosensory cortical prosthesis
Thomson, E. E., Carra, R. B., & Nicolelis, M. A. L. (2013) · Nature Communications · doi:10.1038/ncomms2497 · Cited by 111 · see citing works
A cognitive neuroprosthetic that uses cortical stimulation for somatosensory feedback
Klaes, C., Shi, Y., Kellis, S., Minxha, J., Revechkis, B., & Andersen, R. A. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/5/056024 · Cited by 107 · see citing works
Active upper limb prostheses: a review on current state and upcoming breakthroughs
Marinelli, A., Boccardo, N., Tessari, F., Domenico, D. D., Caserta, G., Canepa, M., Gini, G. C., Barresi, G., Laffranchi, M., Michieli, L. D., et al. (2022) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/acac57 · Cited by 110 · see citing works
Fotopoulou, A., Jenkinson, P. M., Manos Tsakiris, A., Haggard, P., Rudd, A., & Kopelman, M. D. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.10.011 · Cited by 109 · see citing works
Vibrotactile Stimulation Promotes Embodiment of an Alien Hand in Amputees With Phantom Sensations
D’Alonzo, M., Clemente, F., & Cipriani, C. (2014) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2014.2337952 · Cited by 104 · see citing works
“Long-term stability of stimulating spiral nerve cuff electrodes on human peripheral nerves”
Christie, B. P., Freeberg, M., Memberg, W. D., Pinault, G. J. C., Hoyen, H. A., Tyler, D. J., & Triolo, R. J. (2017) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-017-0285-3 · Cited by 97 · see citing works
Neural interfaces for somatosensory feedback: bringing life to a prosthesis
Tyler, D. J. (2015) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000266 · Cited by 105 · see citing works
Physical and chemical awareness from sensing polymeric artificial muscles. Experiments and modeling
Otero, T. F., & Martínez, J. G. (2014) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2014.09.002 · Cited by 105 · see citing works
Bekrater‐Bodmann, R. (2021) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2020.604376 · Cited by 107 · see citing works
Upper limb cortical maps in amputees with targeted muscle and sensory reinnervation
Serino, A., Akselrod, M., Salomon, R., Martuzzi, R., Blefari, M. L., Canzoneri, E., Rognini, G., van der Zwaag, W., Iakova, M., Lüthi, F., et al. (2017) · Brain · doi:10.1093/brain/awx242 · Cited by 102 · see citing works
Self-citationLearning of Artificial Sensation Through Long-Term Home Use of a Sensory-Enabled Prosthesis
Cuberovic, I., Gill, A., Resnik, L. J., Tyler, D. J., & Graczyk, E. L. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00853 · Cited by 99 · see citing works
Embodying the Mind and Representing the Body
Alsmith, A., & de Vignemont, F. (2012) · Review of Philosophy and Psychology · doi:10.1007/s13164-012-0085-4 · Cited by 79 · see citing works
Shared electrophysiology mechanisms of body ownership and motor imagery
Evans, N. J., & Blanke, O. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.09.027 · Cited by 95 · see citing works
Lightening the Perceived Prosthesis Weight with Neural Embodiment Promoted by Sensory Feedback
Preatoni, G., Valle, G., Petrini, F. M., & Raspopović, S. (2021) · Current Biology · doi:10.1016/j.cub.2020.11.069 · Cited by 97 · see citing works
Paradigms for restoration of somatosensory feedback via stimulation of the peripheral nervous system
Pasluosta, C. F., Kiele, P., & Stieglitz, T. (2017) · Clinical Neurophysiology · doi:10.1016/j.clinph.2017.12.027 · Cited by 97 · see citing works
Ownership of an artificial limb induced by electrical brain stimulation
Collins, K. L., Guterstam, A., Cronin, J. A., Olson, J. D., Ehrsson, H. H., & Ojemann, J. G. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1616305114 · Cited by 96 · see citing works
Technological Advances in Prosthesis Design and Rehabilitation Following Upper Extremity Limb Loss
Bates, T. J., Fergason, J. R., & Pierrie, S. N. (2020) · Current Reviews in Musculoskeletal Medicine · doi:10.1007/s12178-020-09656-6 · Cited by 95 · see citing works
Biomimetic encoding model for restoring touch in bionic hands through a nerve interface
Okorokova, E. V., He, Q., & Bensmaı̈a, S. J. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aae398 · Cited by 90 · see citing works
Selectivity and Longevity of Peripheral-Nerve and Machine Interfaces: A Review.
Ghafoor, U., Kim, S., & Hong, K.-S. (2017) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2017.00059 · Cited by 88 · see citing works
“Using TR, sensation in the hand as evoked by a reinnervated chest skin along with other senses like touch, temperature, pain, and a limited graded force discrimination have been demonstrated ( Kuiken et al., 2007b; Marasco et al., 2009, 2011; Schultz et al., 2009; Sensinger et al., 2009).”
Gonzalez, J., Soma, H., Sekine, M., & Yu, W. (2012) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-9-33 · Cited by 87 · see citing works
On prosthetic control: A regenerative agonist-antagonist myoneural interface
Srinivasan, S. S., Carty, M. J., Calvaresi, P., Clites, T. R., Maimon, B. E., Taylor, C. R., Zorzos, A. N., & Herr, H. (2017) · Science Robotics · doi:10.1126/scirobotics.aan2971 · Cited by 92 · see citing works
The robot hand illusion: Inducing proprioceptive drift through visuo-motor congruency
Romano, D., Caffa, E., Arieta, A. H., Brugger, P., & Maravita, A. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.10.033 · Cited by 89 · see citing works
Rohde, M., Wold, A., Karnath, H., & Ernst, M. O. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080688 · Cited by 86 · see citing works
Is an artificial limb embodied as a hand? Brain decoding in prosthetic limb users
Maimon-Mor, R. O., & Makin, T. R. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000729 · Cited by 83 · see citing works
Augmentation-related brain plasticity
Pino, G. D., Maravita, A., Zollo, L., Guglielmelli, E., & Lazzaro, V. D. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00109 · Cited by 81 · see citing works
Restoring tactile and proprioceptive sensation through a brain interface
Tabot, G. A., Kim, S. S., Winberry, J. E., & Bensmaia, S. J. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.08.029 · Cited by 83 · see citing works
HapPro: A Wearable Haptic Device for Proprioceptive Feedback
Rossi, M., Bianchi, M., Battaglia, E., Catalano, M. G., & Bicchi, A. (2018) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2018.2836672 · Cited by 80 · see citing works
The science and engineering behind sensitized brain-controlled bionic hands
Pandarinath, C., & Bensmaı̈a, S. J. (2021) · Physiological Reviews · doi:10.1152/physrev.00034.2020 · Cited by 76 · see citing works
The Rice Haptic Rocker: Skin stretch haptic feedback with the Pisa/IIT SoftHand
Battaglia, E., Clark, J. P., Bianchi, M., Catalano, M. G., Bicchi, A., & O’Malley, M. K. (2017) · IEEE World Haptics Conference (WHC) · doi:10.1109/whc.2017.7989848 · Cited by 76 · see citing works
Recent Advances in Flexible Piezoresistive Arrays: Materials, Design, and Applications
Xu, S., Xu, Z., Li, D., Cui, T., Li, X., Yang, Y., Liu, H., & Ren, T. (2023) · Polymers · doi:10.3390/polym15122699 · Cited by 76 · see citing works
Feel-Good Robotics: Requirements on Touch for Embodiment in Assistive Robotics
Beckerle, P., Kõiva, R., Kirchner, E. A., Bekrater‐Bodmann, R., Dosen, S. S., Christ, O., Abbink, D. A., Castellini, C., & Lenggenhager, B. (2018) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2018.00084 · Cited by 69 · see citing works
Biological and bionic hands: natural neural coding and artificial perception
Bensmaia, S. J. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0209 · Cited by 67 · see citing works
Neural Basis of Touch and Proprioception in Primate Cortex
Delhaye, B. P., Long, K. H., & Bensmaı̈a, S. J. (2018) · Comprehensive physiology · doi:10.1002/j.2040-4603.2018.tb00045.x · Cited by 69 · see citing works
The Embodiment of Objects: Review, Analysis, and Future Directions
Schettler, A., Raja, V., & Anderson, M. L. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01332 · Cited by 70 · see citing works
Schofield, J. S., Shell, C. E., Beckler, D. T., Thumser, Z. C., & Marasco, P. D. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00120 · Cited by 68 · see citing works
Self-citationTieri, G., Gioia, A., Scandola, M., Pavone, E. F., & Aglioti, S. M. (2017) · European Journal of Neuroscience · doi:10.1111/ejn.13545 · Cited by 66 · see citing works
Christ, O., & Reiner, M. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.02.013 · Cited by 65 · see citing works
The Onset Time of the Ownership Sensation in the Moving Rubber Hand Illusion
Kalckert, A., & Ehrsson, H. H. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00344 · Cited by 67 · see citing works
Reflections on the present and future of upper limb prostheses
Farina, D., & Amsuess, S. (2016) · Expert Review of Medical Devices · doi:10.1586/17434440.2016.1159511 · Cited by 65 · see citing works
Roadmap on nanogenerators and piezotronics
Basset, P., Beeby, S., Bowen, C., Chew, Z. J., Delbani, A., Dharmasena, R. D. I. G., Dudem, B., Fan, F. R., Galayko, D., Guo, H., et al. (2022) · APL Materials · doi:10.1063/5.0085850 · Cited by 63 · see citing works
Deeny, S. P., Chicoine, C. L., Hargrove, L. J., Parrish, T. B., & Jayaraman, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112091 · Cited by 62 · see citing works
Wearable multi-sensory haptic devices
Fleck, J. J., Zook, Z. A., Clark, J. P., Preston, D. J., Lipomi, D. J., Pacchierotti, C., & O’Malley, M. K. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00274-w · Cited by 65 · see citing works
Vibrotactile Sensory Substitution Elicits Feeling of Ownership of an Alien Hand
D’Alonzo, M., & Cipriani, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050756 · Cited by 63 · see citing works
Mechanotactile Sensory Feedback Improves Embodiment of a Prosthetic Hand During Active Use
Shehata, A. W., Rehani, M., Jassat, Z. E., & Hebert, J. S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00263 · Cited by 61 · see citing works
Battaglia, E., Clark, J. P., Bianchi, M., Catalano, M. G., Bicchi, A., & O’Malley, M. K. (2019) · IEEE Transactions on Haptics · doi:10.1109/toh.2019.2915075 · Cited by 60 · see citing works
Prostheses as extensions of the body: Progress and challenges
Niedernhuber, M., Barone, D. G., & Lenggenhager, B. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.04.020 · Cited by 58 · see citing works
Current Concepts in Upper-Extremity Amputation
Pierrie, S. N., Gaston, R. G., & Loeffler, B. J. (2018) · The Journal Of Hand Surgery · doi:10.1016/j.jhsa.2018.03.053 · Cited by 58 · see citing works
The benefits of sensation on the experience of a hand: A qualitative case series
Graczyk, E. L., Gill, A., Tyler, D. J., & Resnik, L. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211469 · Cited by 60 · see citing works
Huaroto, J. J., Suárez, E., Krebs, H. I., Marasco, P. D., & Vela, E. A. (2018) · IEEE Robotics and Automation Letters · doi:10.1109/lra.2018.2874379 · Cited by 57 · see citing works
Self-citationSlip Speed Feedback for Grip Force Control
Damian, D. D., Arita, A. H., Martinez, H., & Pfeifer, R. (2012) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2012.2199491 · Cited by 56 · see citing works
Artificial Proprioceptive Feedback for Myoelectric Control
Tobias Pistohl, A., Joshi, D., Ganesh, G., Andrew, J. O., & Nazarpour, K. (2014) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2014.2355856 · Cited by 56 · see citing works
Crossmodal illusions in neurorehabilitation
Bolognini, N., Russo, C., & Vallar, G. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00212 · Cited by 55 · see citing works
Crea, S., D’Alonzo, M., Vitiello, N., & Cipriani, C. (2015) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-015-0069-6 · Cited by 55 · see citing works
Neural correlates of the rubber hand illusion in amputees: A report of two cases
Schmalzl, L., Kalckert, A., Ragnö, C., & Ehrsson, H. H. (2013) · Neurocase · doi:10.1080/13554794.2013.791861 · Cited by 52 · see citing works
Illusory Sense of Human Touch From a Warm and Soft Artificial Hand
Cabibihan, J., Joshi, D., Srinivasa, Y. M., Chan, M. A., & Muruganantham, A. (2014) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2014.2360533 · Cited by 51 · see citing works
Collinger, J. L., Gaunt, R. A., & Schwartz, A. B. (2018) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2018.11.005 · Cited by 52 · see citing works
Improving internal model strength and performance of prosthetic hands using augmented feedback
Shehata, A. W., Engels, L. F., Controzzi, M., Cipriani, C., Scheme, E., & Sensinger, J. W. (2018) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-018-0417-4 · Cited by 51 · see citing works
Toward a Proprioceptive Neural Interface that Mimics Natural Cortical Activity
Tomlinson, T., & Miller, L. E. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-47313-0_20 · Cited by 43 · see citing works
Auditory cues influence the rubber-hand illusion.
Radziun, D., & Ehrsson, H. H. (2018) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037/xhp0000508 · Cited by 48 · see citing works
Schoepp, K. R., Dawson, M. R. W., Schofield, J. S., Carey, J. P., & Hebert, J. S. (2018) · IEEE Journal of Translational Engineering in Health and Medicine · doi:10.1109/jtehm.2018.2866105 · Cited by 50 · see citing works
- Authors
- Marasco, P. D., Kim, K., Colgate, J. E., Peshkin, M. A., & Kuiken, T. A.
- Affiliations
- Shirley Ryan AbilityLab (US)
- Northwestern University (US)
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-01-20
- Volume
- 134
- Issue
- 3
- Pages
- 747-758
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- PMC
- PMC3044830
- OpenAlex
- W2121529660
- Cited by
- 335
- References
- 53
- Citations by year
- 2026: 23 · 2025: 8 · 2024: 21 · 2023: 23 · 2022: 22 · 2021: 25 · 2020: 21 · 2019: 24 · 2018: 34 · 2017: 23 · 2016: 18 · 2015: 24 · 2014: 26 · 2013: 17 · 2012: 16
- FWCI
- 11.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Brain (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Open Access System for Information Sharing (Pohang University of Science and Technology) (submittedVersion)
- Funders
- Chicago Community Trust
- National Institutes of Health
- Defense Advanced Research Projects Agency (N66001-06-C-8005)
- Advanced Research Projects Agency
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01-HD-4-4798, R01-HD-4-3137, N01-HD-53402)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- amputees, artificial limbs, cutaneous feedback, robotic touch, embodiment, rubber hand illusion, sensory substitution, pressure sensors, temporal order judgment, self-image
- MeSH terms
- Amputation Stumps, Biofeedback, Psychology, Hand, Humans, Illusions, Judgment, Male, Perception, Phantom Limb, Surveys and Questionnaires, Robotics, Sensory Thresholds, Temperature, Touch, Prosthesis Implantation, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
