A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

Lysine acetylation targets protein complexes and co-regulates major cellular functions

Choudhary, C., Kumar, C., Gnad, F., Nielsen, M. L., Rehman, M., Walther, T. C., Olsen, J. V., & Mann, M. (2009) · Science · doi:10.1126/science.1175371 · Cited by 4,040

Correlation between Protein and mRNA Abundance in Yeast

Gygi, S. P., Rochon, Y., Franza, B. R., & Aebersold, R. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.3.1720 · Cited by 3,819

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Kaeberlein, M., McVey, M., & Guarente, L. (1999) · Genes & Development · doi:10.1101/gad.13.19.2570 · Cited by 2,253

Extrachromosomal rDNA circles—a cause of aging in yeast

Sinclair, D. A., & Guarente, L. (1997) · Cell · doi:10.1016/s0092-8674(00)80493-6 · Cited by 1,500

DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression

Bishop, D. K., Park, D., Xu, L., & Kleckner, N. (1992) · Cell · doi:10.1016/0092-8674(92)90446-j · Cited by 1,144

Two Distinct Vps34 Phosphatidylinositol 3–Kinase Complexes Function in Autophagy and Carboxypeptidase Y Sorting in Saccharomyces cerevisiae

Kihara, A., Noda, T., Ishihara, N., & Ohsumi, Y. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.3.519 · Cited by 1,004

The MKK2 Pathway Mediates Cold and Salt Stress Signaling in Arabidopsis

Teige, M., Scheikl, E., Eulgem, T., Dóczi, R., Ichimura, K., Shinozaki, K., Dangl, J. L., & Hirt, H. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.06.023 · Cited by 1,002

Formation Process of Autophagosome Is Traced with Apg8/Aut7p in Yeast

Kirisako, T., Baba, M., Ishihara, N., Miyazawa, K., Ohsumi, M., Yoshimori, T., Noda, T., & Ohsumi, Y. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.2.435 · Cited by 881

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

Citorik, R. J., Mimee, M., & Lu, T. K. (2014) · Nature Biotechnology · doi:10.1038/nbt.3011 · Cited by 808

Reduced levels of hsp90 compromise steroid receptor action in vivo

Picard, D., Khursheed, B., Garabedian, M. J., Fortin, M. G., Lindquist, S., & Yamamoto, K. R. (1990) · Nature · doi:10.1038/348166a0 · Cited by 787

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

Dever, T. E., Feng, L., Wek, R. C., Cigan, A. M., Donahue, T. F., & Hinnebusch, A. G. (1992) · Cell · doi:10.1016/0092-8674(92)90193-g · Cited by 776

TLC1 : Template RNA Component of Saccharomyces cerevisiae Telomerase

Singer, M. S., & Gottschling, D. E. (1994) · Science · doi:10.1126/science.7545955 · Cited by 736

Disruption of CREB function in brain leads to neurodegeneration

Mantamadiotis, T., Lemberger, T., Bleckmann, S. C., Kern, H., Kretz, O., Villalba, A. M., Tronche, F., Kellendonk, C., Gau, D., Kapfhammer, J., et al. (2002) · Nature Genetics · doi:10.1038/ng882 · Cited by 684

Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport

Dancis, A., Yuan, D. S., Haile, D., Askwith, C., Eide, D., Moehle, C., Kaplan, J., & Klausner, R. D. (1994) · Cell · doi:10.1016/0092-8674(94)90345-x · Cited by 659

Atg9 vesicles are an important membrane source during early steps of autophagosome formation

Yamamoto, H., Kakuta, S., Watanabe, T. M., Kitamura, A., Sekito, T., Kondo-Kakuta, C., Ichikawa, R., Kinjo, M., & Ohsumi, Y. (2012) · Journal of Cell Biology · doi:10.1083/jcb.201202061 · Cited by 659

Intragenic tandem repeats generate functional variability

Verstrepen, K. J., Jansen, A., Lewitter, F., & Fink, G. R. (2005) · Nature Genetics · doi:10.1038/ng1618 · Cited by 616

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

Mochida, K., Oikawa, Y., Kimura, Y., Kirisako, H., Hirano, H., Ohsumi, Y., & Nakatogawa, H. (2015) · Nature · doi:10.1038/nature14506 · Cited by 611

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

Paeschke, K., Capra, J. A., & Zakian, V. A. (2011) · Cell · doi:10.1016/j.cell.2011.04.015 · Cited by 566

A Genetic Map of the Response to DNA Damage in Human Cells

Olivieri, M., Cho, T., Álvarez-Quilón, A., Li, K., Schellenberg, M. J., Zimmermann, M., Hustedt, N., Rossi, S. E., Adam, S., Melo, H., et al. (2020) · Cell · doi:10.1016/j.cell.2020.05.040 · Cited by 551

Calcineurin is required for virulence of Cryptococcus neoformans

Odom, A., Muir, S., Lim, E., Toffaletti, D. L., Perfect, J., & Heitman, J. (1997) · The EMBO Journal · doi:10.1093/emboj/16.10.2576 · Cited by 516

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

Schlicker, C., Gertz, M., Papatheodorou, P., Kachholz, B., Becker, C. F. W., & Steegborn, C. (2008) · Journal of Molecular Biology · doi:10.1016/j.jmb.2008.07.048 · Cited by 531

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

Mari, M., Griffith, J., Rieter, E., Krishnappa, L., Klionsky, D. J., & Reggiori, F. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200912089 · Cited by 491

Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast

Stathopoulos, A. M., & Cyert, M. S. (1997) · Genes & Development · doi:10.1101/gad.11.24.3432 · Cited by 442

The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene

Marcusson, E. G., Horazdovsky, B. F., Cereghino, J. L., Gharakhanian, E., & Emr, S. D. (1994) · Cell · doi:10.1016/0092-8674(94)90219-4 · Cited by 439

RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit

Xie, Y., & Varshavsky, A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.071022298 · Cited by 436

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

Berger, S. L., Piña, B., Silverman, N., Marcus, G. A., Agapite, J., Regier, J. L., Triezenberg, S. J., & Guarente, L. (1992) · Cell · doi:10.1016/0092-8674(92)90100-q · Cited by 435

Calcineurin Inhibits VCX 1-Dependent H + /Ca 2 + Exchange and Induces Ca 2 + ATPases in Saccharomyces cerevisiae

Cunningham, K. W., & Fink, G. R. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.5.2226 · Cited by 431

Mutational Analysis of Hsp90 Function: Interactions with a Steroid Receptor and a Protein Kinase

Nathan, D. F., & Lindquist, S. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.7.3917 · Cited by 423

An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

Scroggins, B. T., Robzyk, K., Wang, D., Marcu, M. G., Tsutsumi, S., Beebe, K., Cotter, R. J., Felts, S., Toft, D., Karnitz, L., et al. (2007) · Molecular Cell · doi:10.1016/j.molcel.2006.12.008 · Cited by 413

Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases α and δ

Diede, S. J., & Gottschling, D. E. (1999) · Cell · doi:10.1016/s0092-8674(00)81670-0 · Cited by 379

Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae

Kennedy, B. K., Gotta, M., Sinclair, D. A., Mills, K., McNabb, D. S., Murthy, M., Pak, S. M., Laroche, T., Gasser, S. M., & Guarente, L. (1997) · Cell · doi:10.1016/s0092-8674(00)80219-6 · Cited by 375

Fzo1p Is a Mitochondrial Outer Membrane Protein Essential for the Biogenesis of Functional Mitochondria in Saccharomyces cerevisiae

Rapaport, D., Brunner, M., Neupert, W., & Westermann, B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.32.20150 · Cited by 370

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene, MEC1

Morrow, D. M., Tagle, D. A., Shiloh, Y., Collins, F. S., & Hieter, P. (1995) · Cell · doi:10.1016/0092-8674(95)90480-8 · Cited by 370

In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone

Nathan, D. F., Vos, M. H., & Lindquist, S. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.12949 · Cited by 364

Monitoring disulfide bond formation in the eukaryotic cytosol

Østergaard, H., Tachibana, C., & Winther, J. R. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200402120 · Cited by 333

Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae

Matheos, D. P., Kingsbury, T. J., Ahsan, U. S., & Cunningham, K. W. (1997) · Genes & Development · doi:10.1101/gad.11.24.3445 · Cited by 332

Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae

Kirchman, P. A., Kim, S., Lai, C.-Y., & Jazwinski, S. M. (1999) · Genetics · doi:10.1093/genetics/152.1.179 · Cited by 328

Sorting of proteins into multivesicular bodies: ubiquitin‐dependent and ‐independent targeting

Reggiori, F., & Pelham, H. R. B. (2001) · The EMBO Journal · doi:10.1093/emboj/20.18.5176 · Cited by 324

Vesicles carry most exocyst subunits to exocytic sites marked by the remaining two subunits, Sec3p and Exo70p

Boyd, C., Hughes, T., Pypaert, M., & Novick, P. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200408124 · Cited by 312

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

Cyert, M. S., Kunisawa, R., Kaim, D., & Thorner, J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7376 · Cited by 289

Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I

Kim, N., Huang, S.-Y. N., Williams, J. S., Li, Y. C., Clark, A. B., Cho, J.-E., Kunkel, T. A., Pommier, Y., & Jinks-Robertson, S. (2011) · Science · doi:10.1126/science.1205016 · Cited by 291

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

Friedman, J. R., Mourier, A., Yamada, J., McCaffery, J. M., & Nunnari, J. (2015) · eLife · doi:10.7554/elife.07739 · Cited by 291

A Family of Proteins with γ-Adaptin and Vhs Domains That Facilitate Trafficking between the Trans-Golgi Network and the Vacuole/Lysosome

Hirst, J., Lui, W. W. Y., Bright, N. A., Totty, N., Seaman, M. N. J., & Robinson, M. S. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.1.67 · Cited by 291

Xylose isomerase overexpression along with engineering of the pentose phosphate pathway and evolutionary engineering enable rapid xylose utilization and ethanol production by Saccharomyces cerevisiae

Zhou, H., Cheng, J.-S., Wang, B. L., Fink, G. R., & Stephanopoulos, G. (2012) · Metabolic Engineering · doi:10.1016/j.ymben.2012.07.011 · Cited by 287

Upc2p and Ecm22p, Dual Regulators of Sterol Biosynthesis in Saccharomyces cerevisiae

Vik, Å., & Rine, J. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.19.6395-6405.2001 · Cited by 277

Cell cycle-regulated histone acetylation required for expression of the yeast HO gene

Krebs, J. E., Kuo, M.-H., Allis, C. D., & Peterson, C. L. (1999) · Genes & Development · doi:10.1101/gad.13.11.1412 · Cited by 275

Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors.

Marcus, G. A., Silverman, N., Berger, S. L., Horiuchi, J., & Guarente, L. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06806.x · Cited by 276

The Redox Environment in the Mitochondrial Intermembrane Space Is Maintained Separately from the Cytosol and Matrix

Hu, J., Dong, L., & Outten, C. E. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803028200 · Cited by 273

Genome-wide protein–DNA binding dynamics suggest a molecular clutch for transcription factor function

Lickwar, C. R., Mueller, F., Hanlon, S. E., McNally, J. G., & Lieb, J. D. (2012) · Nature · doi:10.1038/nature10985 · Cited by 241

Apg10p, a novel protein‐conjugating enzyme essential for autophagy in yeast

Shintani, T., Mizushima, N., Ogawa, Y., Matsuura, A., Noda, T., & Ohsumi, Y. (1999) · The EMBO Journal · doi:10.1093/emboj/18.19.5234 · Cited by 269

Atg9 Cycles Between Mitochondria and the Pre-Autophagosomal Structure in Yeasts

Reggiori, F., Shintani, T., Chong, H., Nair, U., & Klionsky, D. J. (2005) · Autophagy · doi:10.4161/auto.1.2.1840 · Cited by 266

Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing

Sharon, E., Chen, S.-A. A., Khosla, N. M., Smith, J. D., Pritchard, J. K., & Fraser, H. B. (2018) · Cell · doi:10.1016/j.cell.2018.08.057 · Cited by 225

MMM1 Encodes a Mitochondrial Outer Membrane Protein Essential for Establishing and Maintaining the Structure of Yeast Mitochondria

Burgess, S. M., Delannoy, M., & Jensen, R. E. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.126.6.1375 · Cited by 249

Mitochondrial protein synthesis adapts to influx of nuclear-encoded protein

Richter-Dennerlein, R., Oeljeklaus, S., Lorenzi, I., Ronsör, C., Bareth, B., Schendzielorz, A. B., Wang, C., Warscheid, B., Rehling, P., & Dennerlein, S. (2016) · Cell · doi:10.1016/j.cell.2016.09.003 · Cited by 232

Pif1p Helicase, a Catalytic Inhibitor of Telomerase in Yeast

Zhou, J.-Q., Monson, E. K., Teng, S.-C., Schulz, V. P., & Zakian, V. A. (2000) · Science · doi:10.1126/science.289.5480.771 · Cited by 236

Multiple Regulators of Ty1 Transposition in Saccharomyces cerevisiae Have Conserved Roles in Genome Maintenance

Scholes, D. T., Banerjee, M., Bowen, B., & Curcio, M. J. (2001) · Genetics · doi:10.1093/genetics/159.4.1449 · Cited by 235

Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane

Umebayashi, K., & Nakano, A. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200303088 · Cited by 230

The TEA/ATTS transcription factor CaTec1p regulates hyphal development and virulence in Candida albicans

Schweizer, A., Rupp, S., Taylor, B. N., Röllinghoff, M., & Schröppel, K. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.02132.x · Cited by 232

Mechanism of Metabolic Control

Komeili, A., Wedaman, K. P., O'Shea, E. K., & Powers, T. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.4.863 · Cited by 230

High-Temperature Ethanol Fermentation and Transformation with Linear DNA in the Thermotolerant Yeast Kluyveromyces marxianus DMKU3-1042

Nonklang, S., Abdel-Banat, B. M. A., Cha-aim, K., Moonjai, N., Hoshida, H., Limtong, S., Yamada, M., & Akada, R. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.01854-08 · Cited by 215

Intramembrane Bis-Heme Motif for Transmembrane Electron Transport Conserved in a Yeast Iron Reductase and the Human NADPH Oxidase

Finegold, A. A., Shatwell, K. P., Segal, A. W., Klausner, R. D., & Dancis, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.49.31021 · Cited by 213

Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae

Merz, S., & Westermann, B. (2009) · Genome Biology · doi:10.1186/gb-2009-10-9-r95 · Cited by 213

A Homolog of Voltage-Gated Ca 2+ Channels Stimulated by Depletion of Secretory Ca 2+ in Yeast

Locke, E. G., Bonilla, M., Liang, L., Takita, Y., & Cunningham, K. W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.18.6686-6694.2000 · Cited by 212

Mediator Expression Profiling Epistasis Reveals a Signal Transduction Pathway with Antagonistic Submodules and Highly Specific Downstream Targets

van de Peppel, J., Kettelarij, N., van Bakel, H., Kockelkorn, T. T. J. P., van Leenen, D., & Holstege, F. C. P. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.06.033 · Cited by 211

Isolation of Hsp90 mutants by screening for decreased steroid receptor function.

Bohen, S. P., & Yamamoto, K. R. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.23.11424 · Cited by 195

Multiple Signals from Dysfunctional Mitochondria Activate the Pleiotropic Drug Resistance Pathway in Saccharomyces cerevisiae

Hallstrom, T. C., & Moye-Rowley, W. S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m007338200 · Cited by 194

Mdm12p, a Component Required for Mitochondrial Inheritance That Is Conserved between Budding and Fission Yeast

Berger, K. H., Sogo, L. F., & Yaffe, M. P. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.3.545 · Cited by 197

A Homolog of Mammalian, Voltage-Gated Calcium Channels Mediates Yeast Pheromone-Stimulated Ca 2+ Uptake and Exacerbates the cdc1 (Ts) Growth Defect

Paidhungat, M., & Garrett, S. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.11.6339 · Cited by 191

Telomere length control and transcriptional regulation of subtelomeric adhesins in Candida glabrata

Castaño, I., Pan, S., Zupancic, M., Hennequin, C., Dujon, B., & Cormack, B. P. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04465.x · Cited by 188

Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

Bungert, J., Davé, U., Lim, K. C., Lieuw, K. H., Shavit, J. A., Liu, Q., & Engel, J. D. (1995) · Genes & Development · doi:10.1101/gad.9.24.3083 · Cited by 183

Suppressors of Superoxide Dismutase (SOD1) Deficiency in Saccharomyces cerevisiae

Strain, J., Lorenz, C. R., Bode, J., Garland, S., Smolen, G. A., Ta, D. T., Vickery, L. E., & Culotta, V. C. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.47.31138 · Cited by 181

Mediator protein mutations that selectively abolish activated transcription

Myers, L. C., Gustafsson, C. M., Hayashibara, K. C., Brown, P. O., & Kornberg, R. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.1.67 · Cited by 181

CSD2, CSD3, and CSD4, genes required for chitin synthesis in Saccharomyces cerevisiae: the CSD2 gene product is related to chitin synthases and to developmentally regulated proteins in Rhizobium species and Xenopus laevis.

Bulawa, C. E. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.4.1764 · Cited by 178

Mutations in Alternative Carbon Utilization Pathways in Candida albicans Attenuate Virulence and Confer Pleiotropic Phenotypes

Ramírez, M. A., & Lorenz, M. C. (2007) · Eukaryotic Cell · doi:10.1128/ec.00372-06 · Cited by 174

Antiviral Protein Ski8 Is a Direct Partner of Spo11 in Meiotic DNA Break Formation, Independent of Its Cytoplasmic Role in RNA Metabolism

Arora, C., Kee, K., Maleki, S., & Keeney, S. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00063-2 · Cited by 173

The Saccharomyces cerevisiae Proteome of Oxidized Protein Thiols

Le Moan, N., Clement, G., Le Maout, S., Tacnet, F., & Toledano, M. B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513346200 · Cited by 170

Perturbation of transcription elongation influences the fidelity of internal exon inclusion in Saccharomyces cerevisiae

HOWE, K. J., KANE, C. M., & ARES, M. (2003) · RNA · doi:10.1261/rna.5390803 · Cited by 169

A role for a eukaryotic GrpE-related protein, Mge1p, in protein translocation.

Laloraya, S., Gambill, B. D., & Craig, E. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.14.6481 · Cited by 165

Signaling in the Yeast Pheromone Response Pathway: Specific and High-Affinity Interaction of the Mitogen-Activated Protein (MAP) Kinases Kss1 and Fus3 with the Upstream MAP Kinase Kinase Ste7

Bardwell, L., Cook, J. G., Chang, E. C., Cairns, B. R., & Thorner, J. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.7.3637 · Cited by 161

The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins

Bragoszewski, P., Gornicka, A., Sztolsztener, M. E., & Chacinska, A. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01579-12 · Cited by 149

Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span in Saccharomyces cerevisiae

Park, P. U., Defossez, P.-A., & Guarente, L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3848 · Cited by 155

Rapamycin and Less Immunosuppressive Analogs Are Toxic to Candida albicans and Cryptococcus neoformans via FKBP12-Dependent Inhibition of TOR

Cruz, M. C., Goldstein, A. L., Blankenship, J., Del Poeta, M., Perfect, J. R., McCusker, J. H., Bennani, Y. L., Cardenas, M. E., & Heitman, J. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.11.3162-3170.2001 · Cited by 159

A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.

Shani, N., & Valle, D. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11901 · Cited by 157

PAD1 encodes phenylacrylic acid decarboxylase which confers resistance to cinnamic acid in Saccharomyces cerevisiae

Clausen, M., Lamb, C. J., Megnet, R., & Doerner, P. W. (1994) · Gene · doi:10.1016/0378-1119(94)90363-8 · Cited by 155

A second iron-regulatory system in yeast independent of Aft1p

Rutherford, J. C., Jaron, S., Ray, E., Brown, P. O., & Winge, D. R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.261381198 · Cited by 153

Mmm2p, a Mitochondrial Outer Membrane Protein Required for Yeast Mitochondrial Shape and Maintenance of mtDNA Nucleoids

Youngman, M. J., Hobbs, A. E. A., Burgess, S. M., Srinivasan, M., & Jensen, R. E. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200308012 · Cited by 148

Iron Acquisition from Transferrin by Candida albicans Depends on the Reductive Pathway

Knight, S. A. B., Vilaire, G., Lesuisse, E., & Dancis, A. (2005) · Infection and Immunity · doi:10.1128/iai.73.9.5482-5492.2005 · Cited by 145

Analysis of the oxidative stress regulation of the Candida albicans transcription factor, Cap1p

Zhang, X., De Micheli, M., Coleman, S. T., Sanglard, D., & Moye‐Rowley, W. S. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01877.x · Cited by 146

From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II

Braberg, H., Jin, H., Moehle, E. A., Chan, Y. A., Wang, S., Shales, M., Benschop, J. J., Morris, J. H., Qiu, C., Hu, F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.07.033 · Cited by 143

Autophagy supports Candida glabrata survival during phagocytosis

Roetzer, A., Gratz, N., Kovarik, P., & Schüller, C. (2010) · Cellular Microbiology · doi:10.1111/j.1462-5822.2009.01391.x · Cited by 142

A Selective Transport Route from Golgi to Late Endosomes That Requires the Yeast Gga Proteins

Black, M. W., & Pelham, H. R. B. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.3.587 · Cited by 140

Dual Activators of the Sterol Biosynthetic Pathway of Saccharomyces cerevisiae : Similar Activation/Regulatory Domains but Different Response Mechanisms

Davies, B. S. J., Wang, H. S., & Rine, J. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.16.7375-7385.2005 · Cited by 138

The Aspergillus fumigatus transcriptional activator CpcA contributes significantly to the virulence of this fungal pathogen

Krappmann, S., Bignell, E. M., Reichard, U., Rogers, T., Haynes, K., & Braus, G. H. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04015.x · Cited by 133

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

Breuder, T., Hemenway, C. S., Movva, N. R., Cardenas, M. E., & Heitman, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5372 · Cited by 135

Heat stress-induced life span extension in yeast

Shama, S., Lai, C.-Y., Antoniazzi, J. M., Jiang, J. C., & Jazwinski, S. M. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4279 · Cited by 135

PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene.

Shani, N., Watkins, P. A., & Valle, D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.13.6012 · Cited by 129

Candida glabrata environmental stress response involves Saccharomyces cerevisiae Msn2/4 orthologous transcription factors

Roetzer, A., Gregori, C., Jennings, A. M., Quintin, J., Ferrandon, D., Butler, G., Kuchler, K., Ammerer, G., & Schüller, C. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06301.x · Cited by 124

Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin.

Imai, J., & Yahara, I. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.24.9262-9270.2000 · Cited by 123

A Mutation in a Purported Regulatory Gene Affects Control of Sterol Uptake in Saccharomyces cerevisiae

Crowley, J. H., Leak, F. W., Shianna, K. V., Tove, S., & Parks, L. W. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.16.4177-4183.1998 · Cited by 123

Eukaryotic resistance to fluoride toxicity mediated by a widespread family of fluoride export proteins

Li, S., Smith, K. D., Davis, J. H., Gordon, P. B., Breaker, R. R., & Strobel, S. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1310439110 · Cited by 122