CoChat
Sign Up
Cited by 193

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Towards a molecular understanding of endosomal trafficking by Retromer and Retriever

Chen, Kai‐En, Healy, Michael D., Collins, Brett M.·2019·Traffic
DOI 10.1111/tra.12649
Open this paper in CoChat — free account

Abstract

Endosomes are dynamic intracellular compartments that control the sorting of a constant stream of different transmembrane cargos either for ESCRT‐mediated degradation or for egress and recycling to compartments such as the Golgi and the plasma membrane. The recycling of cargos occurs within tubulovesicular membrane domains and is facilitated by peripheral membrane protein machineries that control both membrane remodelling and selection of specific transmembrane cargos. One of the primary sorting machineries is the Retromer complex, which controls the recycling of a large array of different cargo molecules in cooperation with various sorting nexin (SNX) adaptor proteins. Recently a Retromer‐like complex was also identified that controls plasma membrane recycling of cargos including integrins and lipoprotein receptors. Termed “Retriever,” this complex uses a different SNX family member SNX17 for cargo recognition, and cooperates with the COMMD/CCDC93/CCDC22 (CCC) complex to form a larger assembly called “Commander” to mediate endosomal trafficking. In this review we focus on recent advances that have begun to provide a molecular understanding of these two distantly related transport machineries.

Overview

Integrity signals

Registry

Crossref · 10.1111/tra.12649

Cites

8 of 8 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • SNX17-dependent recycling requires the Retriever complex, the CCC complex, and the actin-regulatory WASH complex.

    “SNX17-dependent recycling requires the Retriever complex (VPS35L, VPS26C, and VPS29), the CCC complex (COMMD/CCDC22/CCDC93), and the actin-regulatory WASH complex”

    From PI(3)P coordinates SNX17- and SNX27-dependent protein recycling for long-term synaptic plasticity (2025) · cites this paper as Chen et al., 2019

  • SNX17-dependent recycling requires the WASH complex and the CCC complex.

    “In addition, SNX17-dependent recycling requires the WASH complex and the CCC complex, which includes coiled-coil domain containing 22 (CCDC22), coiled-coil domain containing 93 (CCDC93), and 10 copper metabolism MURR1 domain (COMMD)-containing proteins (Chen et al., 2019; McNally and Cullen, 2018; Simonetti and Cullen, 2019; Wang et al., 2018a).”

    From Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity (2023) · cites this paper as Chen et al., 2019

  • Retriever is a VPS26C:VPS35L:VPS29 trimer.

    “Retriever, a VPS26C:VPS35L:VPS29 trimer, shares distant homology to Retromer, itself a trimer of VPS29, VPS35, and either VPS26A or VPS26B (paralogues with VPS26C).2,15”

    From Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome (2023) · cites this paper as [15]

  • Retriever shares distant homology to Retromer.

    “Retriever, a VPS26C:VPS35L:VPS29 trimer, shares distant homology to Retromer, itself a trimer of VPS29, VPS35, and either VPS26A or VPS26B (paralogues with VPS26C).2,15”

    From Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome (2023) · cites this paper as [15]

  • Recycling of internalized membrane proteins back to the cell surface is achieved by at least two distinct pathways, the SNX27-Retromer and SNX17-Retriever pathways.

    “In recent years, it has become clear that recycling of internalized membrane proteins back to the cell surface is achieved by at least 2 distinct pathways – the SNX27-Retromer and SNX17-Retriever pathways (McNally et al., 2017; Chen et al., 2019; McDonald, 2020).”

    From Dual endomembrane recycling pathways function in parallel to support synapse maintenance and plasticity (2025) · cites this paper as Chen et al., 2019

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 135

  1. 10.1242/jcs.216499 · DOI · Paper page
  2. 10.1038/s41580-018-0053-7 · DOI · Paper page
  3. 10.1111/tra.12574 · DOI
  4. 10.1083/jcb.137.1.79 · DOI · Paper page
  5. 10.1083/jcb.142.3.665 · DOI · Paper page
  6. 10.1016/j.ajhg.2011.06.001 · DOI · Paper page
  7. 10.1016/j.ajhg.2011.06.008 · DOI · Paper page
  8. 10.1007/s13311-014-0321-y · DOI · Paper page
  9. 10.1038/mp.2015.100 · DOI · Paper page
  10. 10.1002/ana.20667 · DOI · Paper page
  11. 10.1016/j.neurobiolaging.2012.04.020 · DOI · Paper page
  12. 10.1038/nchembio.1508 · DOI · Paper page
  13. 10.1016/j.tins.2017.08.003 · DOI · Paper page
  14. 10.1111/j.1600-0854.2011.01284.x · DOI
  15. 10.1111/j.1600-0854.2007.00688.x · DOI
  16. 10.1073/pnas.1410552111 · DOI · Paper page
  17. 10.1111/j.1600-0854.2005.00328.x · DOI · Paper page
  18. 10.1091/mbc.11.12.4105 · DOI · Paper page
  19. 10.1038/nature06216 · DOI · Paper page
  20. 10.1038/s41586-018-0526-z · DOI · Paper page
  21. 10.1111/j.1600-0854.2010.01124.x · DOI · Paper page
  22. 10.1016/j.cell.2016.10.056 · DOI · Paper page
  23. 10.1242/jcs.071977 · DOI
  24. 10.1073/pnas.1316482111 · DOI
  25. 10.1111/tra.12237 · DOI
  26. 10.1083/jcb.200804048 · DOI · Paper page
  27. 10.1242/jcs.048686 · DOI · Paper page
  28. 10.15252/embj.201797128 · DOI · Paper page
  29. 10.1242/jcs.217398 · DOI · Paper page
  30. 10.1242/jcs.216630 · DOI · Paper page
  31. ChandraM CollinsBM. The Phox homology (PX) domain. In:Advances in Experimental Medicine and Biology. New York NY: Springer;2018. · DOI
  32. 10.1042/BJ20111226 · DOI · Paper page
  33. 10.1016/j.tibs.2012.09.001 · DOI
  34. 10.1016/j.tcb.2015.09.005 · DOI
  35. 10.1038/35083051 · DOI
  36. 10.1091/mbc.8.8.1529 · DOI
  37. 10.1242/jcs.02568 · DOI
  38. 10.1083/jcb.201702137 · DOI · Paper page
  39. 10.1128/MCB.00156-06 · DOI
  40. 10.1091/mbc.e03-09-0711 · DOI
  41. 10.1038/ncb2281 · DOI · Paper page
  42. 10.1128/JVI.00757-11 · DOI
  43. 10.1016/j.devcel.2009.04.016 · DOI
  44. 10.1038/nsmb954 · DOI
  45. 10.1038/s41467-018-06114-3 · DOI · Paper page
  46. 10.1083/jcb.201703015 · DOI · Paper page
  47. 10.1038/ncb2721 · DOI · Paper page
  48. 10.1371/journal.pone.0020420 · DOI · Paper page
  49. 10.1083/jcb.201806153 · DOI · Paper page
  50. 10.1111/tra.12542 · DOI
  51. 10.1083/jcb.200312055 · DOI · Paper page
  52. 10.1083/jcb.200312034 · DOI · Paper page
  53. 10.1186/s12915-016-0345-3 · DOI
  54. 10.1126/science.1256898 · DOI
  55. 10.1083/jcb.200609161 · DOI · Paper page
  56. 10.1038/cr.2011.167 · DOI
  57. 10.1016/j.cmet.2013.01.013 · DOI · Paper page
  58. 10.1242/jcs.060574 · DOI
  59. 10.1083/jcb.201806153 · DOI · Paper page
  60. 10.1242/jcs.201905 · DOI
  61. 10.1083/jcb.201004060 · DOI · Paper page
  62. 10.1038/ncb2252 · DOI · Paper page
  63. 10.1073/pnas.1017110108 · DOI · Paper page
  64. 10.1242/jcs.158204 · DOI
  65. 10.1073/pnas.1216229110 · DOI · Paper page
  66. 10.1038/nsmb.3290 · DOI · Paper page
  67. 10.1091/mbc.E15-12-0851 · DOI
  68. 10.1073/pnas.1412415111 · DOI · Paper page
  69. 10.1038/nn1953 · DOI · Paper page
  70. 10.1074/jbc.RA117.000735 · DOI
  71. 10.1016/j.molcel.2017.05.020 · DOI
  72. 10.1242/jcs.071472 · DOI · Paper page
  73. 10.1038/ncomms13305 · DOI · Paper page
  74. 10.1016/j.devcel.2014.04.010 · DOI · Paper page
  75. 10.1038/nsmb.2414 · DOI
  76. 10.1242/jcs.156299 · DOI · Paper page
  77. 10.1111/j.1365-2958.2007.05604.x · DOI
  78. 10.1016/j.chom.2013.06.001 · DOI
  79. 10.1073/pnas.1715361115 · DOI
  80. 10.1038/s41467-017-01512-5 · DOI
  81. 10.1073/pnas.1717383115 · DOI
  82. 10.1016/j.tim.2018.04.001 · DOI
  83. 10.1016/j.cels.2018.06.010 · DOI
  84. 10.1371/journal.ppat.1004699 · DOI
  85. 10.1073/pnas.1302164110 · DOI
  86. 10.1007/s00018-015-2027-7 · DOI
  87. Groppelli E, 2014, Retromer regulates HIV‐1 envelope glycoprotein trafficking and incorporation into virions, PLoS Pathog, 10
  88. 10.1007/s11262-017-1504-5 · DOI
  89. 10.1016/j.devcel.2009.09.010 · DOI · Paper page
  90. 10.1016/j.devcel.2009.09.009 · DOI · Paper page
  91. 10.1073/pnas.0913293107 · DOI · Paper page
  92. 10.1091/mbc.E14-06-1073 · DOI · Paper page
  93. 10.1042/BJ20111761 · DOI · Paper page
  94. 10.1038/nsmb.1792 · DOI
  95. 10.1242/jcs.144659 · DOI
  96. 10.1091/mbc.e11-12-1059 · DOI · Paper page
  97. 10.1128/MCB.01288-12 · DOI · Paper page
  98. 10.1242/jcs.196758 · DOI
  99. 10.1038/ncomms4828 · DOI · Paper page
  100. 10.1016/j.cub.2014.07.004 · DOI
  101. 10.1091/mbc.e11-11-0915 · DOI
  102. 10.1016/j.celrep.2015.08.001 · DOI
  103. 10.1091/mbc.E19-01-0044 · DOI
  104. Wang W, 2017, A conserved retromer sorting motif is essential for mitochondrial DLP1 recycling by VPS35 in Parkinson's disease model, Hum Mol Genet, 26, 781
  105. 10.1038/nm.3983 · DOI
  106. 10.1016/j.cub.2010.05.066 · DOI
  107. 10.1242/jcs.204537 · DOI
  108. 10.1111/j.1600-0854.2007.00652.x · DOI · Paper page
  109. 10.1111/j.1600-0854.2012.01334.x · DOI · Paper page
  110. 10.1016/j.cell.2013.01.051 · DOI
  111. 10.1074/jbc.M113.488627 · DOI
  112. 10.1093/emboj/21.11.2557 · DOI · Paper page
  113. 10.1016/j.cels.2017.04.006 · DOI · Paper page
  114. 10.1038/nature14877 · DOI
  115. 10.1083/jcb.201111121 · DOI · Paper page
  116. 10.1038/ejhg.2014.278 · DOI · Paper page
  117. 10.1074/jbc.M501928200 · DOI · Paper page
  118. 10.7554/eLife.35898 · DOI · Paper page
  119. 10.1074/jbc.M111.302216 · DOI
  120. 10.1093/hmg/11.2.165 · DOI · Paper page
  121. 10.1074/jbc.C300391200 · DOI
  122. 10.1053/j.gastro.2007.07.020 · DOI
  123. 10.1083/jcb.201505108 · DOI · Paper page
  124. 10.1172/JCI66466 · DOI · Paper page
  125. 10.1002/jcb.26151 · DOI
  126. 10.1016/j.bbadis.2013.09.014 · DOI
  127. 10.1016/j.cell.2015.09.053 · DOI · Paper page
  128. 10.15252/msb.20167490 · DOI
  129. 10.1038/emboj.2010.89 · DOI
  130. 10.1016/j.celrep.2018.07.107 · DOI
  131. 10.7554/eLife.24722 · DOI
  132. 10.1016/j.celrep.2018.06.056 · DOI
  133. 10.1107/S1744309113027371 · DOI
  134. 10.1371/journal.pone.0030220 · DOI
  135. 10.1128/MCB.01932-06 · DOI · Paper page

Cited by

Sorted by citations

Metadata

Authors
Chen, K., Healy, M. D., & Collins, B. M.
Affiliations
Institute for Molecular Bioscience University of Queensland St. Lucia Queensland Australia
ORCID
Venue
Traffic
Publisher
Wiley
Published
2019-06-20
Volume
20
Issue
7
Pages
465-478
ISSN
  • 1398-9219
  • 1600-0854
DOI
10.1111/tra.12649
Cited by
193
References
8
Language
en
Licence
Funders
  • Australian Research Council (DP160101743, APP1136021, A2018627S)
  • National Health and Medical Research Council (APP1136021)
  • Australian Institute of Nuclear Science and Engineering

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review