Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Polymeropoulos, Mihael H., Lavedan, Christian, Leroy, Elisabeth, Ide, Susan E., Dehejia, Anindya, Dutra, Amalia, Pike, Brian, Root, Holly +12 more·1997·Science

Cited by (251)

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    Breid, Sara, Bernis, Maria E., Babila, Julius T., Garza, Maria C., Wille, Holger, Tamgüney, Gültekin · 2016 · Journal of Virology
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    Kohl, Zacharias, Winner, Beate, Ubhi, Kiren, Rockenstein, Edward, Mante, Michael, Münch, Martina, Barlow, Carolee, Carter, Todd, Masliah, Eliezer, Winkler, Jürgen · 2012 · European Journal of Neuroscience
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    Braidy, Nady, Gai, Wei-Ping, Xu, Ying Hua, Sachdev, Perminder, Guillemin, Gilles J, Jiang, Xing-Mai, Ballard, J William O, Horan, Martin P, Fang, Zhi Ming, Chong, Beng H et al. · 2013 · Translational Neurodegeneration
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    Stanga, Serena, Caretto, Anna, Boido, Marina, Vercelli, Alessandro · 2020 · International Journal of Molecular Sciences
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    Pabon, Mibel M., Jernberg, Jennifer N., Morganti, Josh, Contreras, Jessika, Hudson, Charles E., Klein, Ronald L., Bickford, Paula C. · 2012 · PLoS ONE
  16. Striatal glutamatergic hyperactivity in Parkinson's disease
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    Charlett, A., Dobbs, R. J., Dobbs, S. M., Weller, C., Brady, P., Peterson, D.W. · 2009 · Acta Neurologica Scandinavica
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    Kauwe, John S. K., Jacquart, Sarah, Chakraverty, Sumi, Wang, Jun, Mayo, Kevin, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M. · 2007 · Annals of Neurology
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    Takeda, A., Hashimoto, M., Mallory, M., Sundsumo, M., Hansen, L., Masliah, E. · 2000 · Acta Neuropathologica
  21. Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration
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  23. O-GlcNAcase Inhibitor ASN90 is a Multimodal Drug Candidate for Tau and α-Synuclein Proteinopathies
    Permanne, Bruno, Sand, Astrid, Ousson, Solenne, Nény, Maud, Hantson, Jennifer, Schubert, Ryan, Wiessner, Christoph, Quattropani, Anna, Beher, Dirk · 2022 · ACS Chemical Neuroscience
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  27. Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease
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  29. α‐Synuclein promotes clathrin‐mediated NMDA receptor endocytosis and attenuates NMDA‐induced dopaminergic cell death
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  30. Native Top-Down Mass Spectrometry and Ion Mobility MS for Characterizing the Cobalt and Manganese Metal Binding of α-Synuclein Protein
    Wongkongkathep, Piriya, Han, Jong Yoon, Choi, Tae Su, Yin, Sheng, Kim, Hugh I., Loo, Joseph A. · 2018 · Journal of the American Society for Mass Spectrometry
  31. Vulnerability of mesostriatal dopaminergic neurons in Parkinson’s disease
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  35. Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain
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  36. Early and persistent expression of phosphorylated α-synuclein in the enteric nervous system of A53T mutant human α-synuclein transgenic mice
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  38. Relevance of chronic stress and the two faces of microglia in Parkinson's disease
    Herrera, Antonio J., Espinosa-Oliva, Ana M., Carrillo-Jiménez, Alejandro, Oliva-Martín, María J., García-Revilla, Juan, García-Quintanilla, Alberto, de Pablos, Rocío M., Venero, José L. · 2015 · Frontiers in Cellular Neuroscience
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  43. Adeno-Associated Virus Expression of α-Synuclein as a Tool to Model Parkinson’s Disease: Current Understanding and Knowledge Gaps
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  46. Early low-dose ghrelin intervention via miniosmotic pumps could protect against the progressive dopaminergic neuron loss in Parkinson's disease mice
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