Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
Polymeropoulos, Mihael H., Lavedan, Christian, Leroy, Elisabeth, Ide, Susan E., Dehejia, Anindya, Dutra, Amalia, Pike, Brian, Root, Holly +12 more·1997·Science
Cited by (251)
Items 101–200 of 251
- Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s diseaseTokuda, Takahiko, Salem, Sultan A., Allsop, David, Mizuno, Toshiki, Nakagawa, Masanori, Qureshi, Mohamed M., Locascio, Joseph J., Schlossmacher, Michael G., El-Agnaf, Omar M.A. · 2006 · Biochemical and Biophysical Research Communications
- Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-SynucleinWillingham, Stephen, Outeiro, Tiago Fleming, DeVit, Michael J., Lindquist, Susan L., Muchowski, Paul J. · 2003 · Science
- Degradation of α-Synuclein by ProteasomeBennett, M. Catherine, Bishop, John F., Leng, Yan, Chock, P. Boon, Chase, Thomas N., Mouradian, M. Maral · 1999 · Journal of Biological Chemistry
- MHCII Is Required for -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic NeurodegenerationHarms, A. S., Cao, S., Rowse, A. L., Thome, A. D., Li, X., Mangieri, L. R., Cron, R. Q., Shacka, J. J., Raman, C., Standaert, D. G. · 2013 · Journal of Neuroscience
- α-synuclein in the pathophysiology of Alzheimer’s diseaseTwohig, Daniel, Nielsen, Henrietta M. · 2019 · Molecular Neurodegeneration
- β-Synuclein Inhibits α-Synuclein AggregationHashimoto, Makoto, Rockenstein, Edward, Mante, Michael, Mallory, Margaret, Masliah, Eliezer · 2001 · Neuron
- Exploring Braak’s hypothesis of Parkinson’s diseaseRietdijk, Carmen D., Perez-Pardo, Paula, Garssen, Johan, van Wezel, Richard J. A., Kraneveld, Aletta D. · 2017 · Frontiers in Neurology
- Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegenerationMollenhauer, Brit, Cullen, Valerie, Kahn, Ilana, Krastins, Bryan, Outeiro, Tiago F., Pepivani, Imelda, Ng, Juliana, Schulz-Schaeffer, Walter, Kretzschmar, Hans A., McLean, Pamela J. et al. · 2008 · Experimental Neurology
- α-Synuclein Binds to Tau and Stimulates the Protein Kinase A-catalyzed Tau Phosphorylation of Serine Residues 262 and 356Jensen, Poul Henning, Hager, Henrik, Nielsen, Morten S., Højrup, Peter, Gliemann, Jørgen, Jakes, Ross · 1999 · Journal of Biological Chemistry
- The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s DiseaseMonzio Compagnoni, Giacomo, Di Fonzo, Alessio, Corti, Stefania, Comi, Giacomo P., Bresolin, Nereo, Masliah, Eliezer · 2020 · Molecular Neurobiology
- Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and AtherosclerosisAltamura, Sandro, Muckenthaler, Martina U. · 2009 · Journal of Alzheimer's Disease
- Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s DiseaseGao, Hui-Ming, Zhang, Feng, Zhou, Hui, Kam, Wayneho, Wilson, Belinda, Hong, Jau-Shyong · 2011 · Environmental Health Perspectives
- Brain iron pathways and their relevance to Parkinson's diseaseBerg, D, Gerlach, M., Youdim, M. B. H., Double, K. L., Zecca, L., Riederer, P., Becker, G. · 2001 · Journal of Neurochemistry
- Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protectionChung, Chee Yeun, Seo, Hyemyung, Sonntag, Kai Christian, Brooks, Andrew, Lin, Ling, Isacson, Ole · 2005 · Human Molecular Genetics
- Full length α-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjectsBorghi, Roberta, Marchese, Roberta, Negro, Alessandro, Marinelli, Lucio, Forloni, Gianluigi, Zaccheo, Damiano, Abbruzzese, Giovanni, Tabaton, Massimo · 2000 · Neuroscience Letters
- Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's diseaseKoprich, James B, Reske-Nielsen, Casper, Mithal, Prabhakar, Isacson, Ole · 2008 · Journal of Neuroinflammation
- The role of Nrf2 signaling in counteracting neurodegenerative diseasesDinkova‐Kostova, Albena T., Kostov, Rumen V., Kazantsev, Aleksey G. · 2018 · The FEBS Journal
- MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degenerationCebrián, Carolina, Zucca, Fabio A., Mauri, Pierluigi, Steinbeck, Julius A., Studer, Lorenz, Scherzer, Clemens R., Kanter, Ellen, Budhu, Sadna, Mandelbaum, Jonathan, Vonsattel, Jean P. et al. · 2014 · Nature Communications
- Proposed neuropathological criteria for the <i>post mortem</i> diagnosis of multiple system atrophyTrojanowski, J. Q., Revesz, T., the Neuropathology Working Group on MSA · 2007 · Neuropathology and Applied Neurobiology
- Accumulation of α-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophyWakabayashi, K., Hayashi, Shintaro, Kakita, Akiyoshi, Yamada, Mitsunori, Toyoshima, Yasuko, Yoshimoto, Makoto, Takahashi, Hitoshi · 1998 · Acta Neuropathologica
- Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson modelJanezic, Stephanie, Threlfell, Sarah, Dodson, Paul D., Dowie, Megan J., Taylor, Tonya N., Potgieter, Dawid, Parkkinen, Laura, Senior, Steven L., Anwar, Sabina, Ryan, Brent et al. · 2013 · Proceedings of the National Academy of Sciences
- U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s diseaseBai, Bing, Hales, Chadwick M., Chen, Ping-Chung, Gozal, Yair, Dammer, Eric B., Fritz, Jason J., Wang, Xusheng, Xia, Qiangwei, Duong, Duc M., Street, Craig et al. · 2013 · Proceedings of the National Academy of Sciences
- Role of the JAK/STAT signaling pathway in regulation of innate immunity in neuroinflammatory diseasesYan, Zhaoqi, Gibson, Sara A., Buckley, Jessica A., Qin, Hongwei, Benveniste, Etty N. · 2018 · Clinical Immunology
- Local gene knockdown in the brain using viral-mediated RNA interferenceHommel, Jonathan D, Sears, Robert M, Georgescu, Dan, Simmons, Diana L, DiLeone, Ralph J · 2003 · Nature Medicine
- Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair MacroautophagyTanik, Selcuk A., Schultheiss, Christine E., Volpicelli-Daley, Laura A., Brunden, Kurt R., Lee, Virginia M.Y. · 2013 · Journal of Biological Chemistry
- Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiationDettmer, Ulf, Newman, Andrew J., Soldner, Frank, Luth, Eric S., Kim, Nora C., von Saucken, Victoria E., Sanderson, John B., Jaenisch, Rudolf, Bartels, Tim, Selkoe, Dennis · 2015 · Nature Communications
- PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neuronsWood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey S. Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma et al. · 2008 · PLoS ONE
- Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disordersDaniele, Stefano G., Béraud, Dawn, Davenport, Connor, Cheng, Kui, Yin, Hang, Maguire-Zeiss, Kathleen A. · 2015 · Science Signaling
- Alpha‐Synuclein as a Biomarker for Parkinson's DiseaseAtik, Anzari, Stewart, Tessandra, Zhang, Jing · 2016 · Brain Pathology
- Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseasesAlexander, Adanna G., Marfil, Vanessa, Li, Chris · 2014 · Frontiers in Genetics
- The identity and function of microglia in neurodegenerationSong, Wilbur M., Colonna, Marco · 2018 · Nature Immunology
- Oxidative and nitrosative stress in Parkinson's diseaseTsang, Anthony H.K., Chung, Kenny K.K. · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagementSchipper, Hyman M., Song, Wei, Zukor, Hillel, Hascalovici, Jacob R., Zeligman, David · 2009 · Journal of Neurochemistry
- Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exerciseMicheli, Laura, Ceccarelli, Manuela, D’Andrea, Giorgio, Tirone, Felice · 2018 · Brain Research Bulletin
- Behavioral and Neurochemical Effects of Wild-Type and Mutated Human α-Synuclein in Transgenic MiceRichfield, Eric K., Thiruchelvam, Mona J., Cory-Slechta, Deborah A., Wuertzer, Charles, Gainetdinov, Raul R., Caron, Marc G., Di Monte, Donato A., Federoff, Howard J. · 2002 · Experimental Neurology
- Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseasesGan, Li, Johnson, Jeffrey A. · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Intraneuronal dopamine-quinone synthesis: a reviewSulzer, David, Zecca, Luigi · 1999 · Neurotoxicity Research
- Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathologyDzamko, Nicolas, Gysbers, Amanda, Perera, Gayathri, Bahar, Anita, Shankar, Amrita, Gao, Jianqun, Fu, YuHong, Halliday, Glenda M. · 2017 · Acta Neuropathologica
- Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase PromoterMatsuoka, Yasuji, Vila, Miquel, Lincoln, Sarah, McCormack, Alison, Picciano, Melanie, LaFrancois, John, Yu, Xin, Dickson, Dennis, Langston, William J., McGowan, Eileen et al. · 2001 · Neurobiology of Disease
- Individual dopaminergic neurons show raised iron levels in Parkinson diseaseOakley, A. E., Collingwood, J. F., Dobson, J., Love, G., Perrott, H. R., Edwardson, J. A., Elstner, M., Morris, C. M. · 2007 · Neurology
- In Situ and in Vitro Study of Colocalization and Segregation of α-Synuclein, Ubiquitin, and Lipids in Lewy BodiesGai, W.P., Yuan, H.X., Li, X.Q., Power, J.T.H., Blumbergs, P.C., Jensen, P.H. · 2000 · Experimental Neurology
- Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivoAngot, Elodie, Steiner, Jennifer A., Lema Tomé, Carla M., Ekström, Peter, Mattsson, Bengt, Björklund, Anders, Brundin, Patrik · 2012 · PLoS ONE
- Tyrosine Hydroxylase and Parkinson’s DiseaseHaavik, Jan, Toska, Karen · 1998 · Molecular Neurobiology
- T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?Appel, Stanley H., Beers, David R., Henkel, Jenny S. · 2010 · Trends in Immunology
- Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's DiseaseSanchez-Guajardo, Vanesa, Febbraro, Fabia, Kirik, Deniz, Romero-Ramos, Marina · 2010 · PLoS ONE
- Neurological and Neurodegenerative Alterations in a Transgenic Mouse Model Expressing Human α-Synuclein under Oligodendrocyte Promoter: Implications for Multiple System AtrophyShults, Clifford W., Rockenstein, Edward, Crews, Leslie, Adame, Anthony, Mante, Michael, Larrea, Gabriel, Hashimoto, Makoto, Song, David, Iwatsubo, Takeshi, Tsuboi, Kyoko et al. · 2005 · The Journal of Neuroscience
- Molecular pathogenesis of Parkinson's diseaseGandhi, Sonia, Wood, Nicholas W. · 2005 · Human Molecular Genetics
- Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studiesUchihara, Toshiki, Giasson, Benoit I. · 2016 · Acta Neuropathologica
- Role of α-Synuclein in Inducing Innate and Adaptive Immunity in Parkinson DiseaseAllen Reish, Heather E., Standaert, David G. · 2015 · Journal of Parkinson’s Disease
- Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseOverk, Cassia R., Masliah, Eliezer · 2014 · Biochemical Pharmacology
- NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophyArima, K., Uéda, Kenji, Sunohara, Nobuhiko, Arakawa, Kenji, Hirai, Shigeo, Nakamura, Minako, Tonozuka-Uehara, Haruko, Kawai, Mitsuru · 1998 · Acta Neuropathologica
- Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and neurodegeneration in a model of Parkinson diseaseHarms, Ashley S., Thome, Aaron D., Yan, Zhaoqi, Schonhoff, Aubrey M., Williams, Gregory P., Li, Xinru, Liu, Yudong, Qin, Hongwei, Benveniste, Etty N., Standaert, David G. · 2018 · Experimental Neurology
- α-Synuclein activates stress signaling protein kinases in THP-1 cells and microgliaKlegeris, Andis, Pelech, Steven, Giasson, Benoit I., Maguire, John, Zhang, Hong, McGeer, Edith G., McGeer, Patrick L. · 2008 · Neurobiology of Aging
- Deep learning for freezing of gait detection in Parkinson’s disease patients in their homes using a waist-worn inertial measurement unitCamps, Julià, Samà, Albert, Martín, Mario, Rodríguez-Martín, Daniel, Pérez-López, Carlos, Moreno Arostegui, Joan M., Cabestany, Joan, Català, Andreu, Alcaine, Sheila, Mestre, Berta et al. · 2018 · Knowledge-Based Systems
- Microglia in Parkinson's diseaseHo, Margaret S. · 2019 · Advances in Experimental Medicine and Biology
- Mitochondrial Medicine for Aging and Neurodegenerative DiseasesReddy, P. Hemachandra · 2008 · NeuroMolecular Medicine
- Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s DiseaseLi, Yunna, Xia, Yun, Yin, Sijia, Wan, Fang, Hu, Junjie, Kou, Liang, Sun, Yadi, Wu, Jiawei, Zhou, Qiulu, Huang, Jinsha et al. · 2021 · Frontiers in Immunology
- Inflammation is genetically implicated in Parkinson’s diseaseDzamko, N., Geczy, C.L, Halliday, G.M · 2015 · Neuroscience
- In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural CellsDettmer, Ulf, Newman, Andrew J., Luth, Eric S., Bartels, Tim, Selkoe, Dennis · 2013 · Journal of Biological Chemistry
- Interaction between Aβ Peptide and α Synuclein: Molecular Mechanisms in Overlapping Pathology of Alzheimer’s and Parkinson’s in Dementia with Lewy Body DiseaseMandal, Pravat K., Pettegrew, Jay W., Masliah, Eliezer, Hamilton, Ronald L., Mandal, Ratna · 2006 · Neurochemical Research
- Alpha synuclein is transported into and out of the brain by the blood-brain barrierSui, Yu-Ting, Bullock, Kristin M., Erickson, Michelle A., Zhang, Jing, Banks, W.A. · 2014 · Peptides
- CHIP: a quality-control E3 ligase collaborating with molecular chaperonesMurata, Shigeo, Chiba, Tomoki, Tanaka, Keiji · 2003 · The International Journal of Biochemistry & Cell Biology
- Dopamine Oxidation and AutophagyMuñoz, Patricia, Huenchuguala, Sandro, Paris, Irmgard, Segura-Aguilar, Juan · 2012 · Parkinson's Disease
- Cerebrospinal fluid biomarkers in Parkinson diseaseParnetti, Lucilla, Castrioto, Anna, Chiasserini, Davide, Persichetti, Emanuele, Tambasco, Nicola, El-Agnaf, Omar, Calabresi, Paolo · 2013 · Nature Reviews Neurology
- Proteolytic stress: A unifying concept for the etiopathogenesis of Parkinson’s diseaseMcNaught, Kevin St. P., Olanow, C. Warren · 2003 · Annals of Neurology
- Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathologyManfredsson, Fredric P., Luk, Kelvin C., Benskey, Matthew J., Gezer, Aysegul, Garcia, Joanna, Kuhn, Nathan C., Sandoval, Ivette M., Patterson, Joseph R., O'Mara, Alana, Yonkers, Reid et al. · 2018 · Neurobiology of Disease
- The Role of LRRK2 in Neurodegeneration of Parkinson DiseaseRui, Qin, Ni, Haibo, Li, Di, Gao, Rong, Chen, Gang · 2018 · Current Neuropharmacology
- α‐Synuclein produces a long‐lasting increase in neurotransmitter releaseLiu, Shumin, Ninan, Ipe, Antonova, Irina, Battaglia, Fortunato, Trinchese, Fabrizio, Narasanna, Archana, Kolodilov, Nikolai, Dauer, William, Hawkins, Robert D, Arancio, Ottavio · 2004 · The EMBO Journal
- Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicityBido, Simone, Muggeo, Sharon, Massimino, Luca, Marzi, Matteo Jacopo, Giannelli, Serena Gea, Melacini, Elena, Nannoni, Melania, Gambarè, Diana, Bellini, Edoardo, Ordazzo, Gabriele et al. · 2021 · Nature Communications
- Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's DiseaseTroncoso-Escudero, Paulina, Parra, Alejandra, Nassif, Melissa, Vidal, Rene L. · 2018 · Frontiers in Neurology
- rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegenerationOliveras-Salvá, Marusela, Van der Perren, Anke, Casadei, Nicolas, Stroobants, Stijn, Nuber, Silke, D’Hooge, Rudi, Van den Haute, Chris, Baekelandt, Veerle · 2013 · Molecular Neurodegeneration
- Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytesRannikko, Emmy H., Weber, Stephanie S., Kahle, Philipp J. · 2015 · BMC Neuroscience
- Prion-like spread of protein aggregates in neurodegenerationPolymenidou, Magdalini, Cleveland, Don W. · 2012 · Journal of Experimental Medicine
- Point Mutations (Thr240Arg and Ala311Stop) in theParkinGeneHattori, Nobutaka, Matsumine, Hiroto, Asakawa, Shuichi, Kitada, Tohru, Yoshino, Hiroyo, Elibol, Blüent, Brookes, Anthony J., Yamamura, Yasuhiro, Kobayashi, Tomonori, Wang, Mei et al. · 1998 · Biochemical and Biophysical Research Communications
- The role of mitochondria in inherited neurodegenerative diseasesKwong, Jennifer Q., Beal, M. Flint, Manfredi, Giovanni · 2006 · Journal of Neurochemistry
- Premotor Parkinson’s disease: Concepts and definitionsSiderowf, Andrew, Lang, Anthony E. · 2012 · Movement Disorders
- Lewy Body Pathology in Alzheimer's DiseaseKotzbauer, Paul T., Tojanowski, John Q., Lee, Virginia M. V. · 2001 · Journal of Molecular Neuroscience
- Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulationLiu, Guoxiang, Yu, Jia, Ding, Jinhui, Xie, Chengsong, Sun, Lixin, Rudenko, Iakov, Zheng, Wang, Sastry, Namratha, Luo, Jing, Rudow, Gay et al. · 2014 · Journal of Clinical Investigation
- Novel tactics for neuroprotection in Parkinson's disease: role of antibiotics, polyphenols and neuropeptidesReglodi, Dora, Renaud, Justine, Tamas, Andrea, Tizabi, Yousef, Socías, Sergio B., Del-Bel, Elaine, Raisman-Vozari, Rita · 2017 · Progress in Neurobiology
- Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagyFussi, Natascha, Höllerhage, Matthias, Chakroun, Tasnim, Nykänen, Niko-Petteri, Rösler, Thomas W., Koeglsperger, Thomas, Wurst, Wolfgang, Behrends, Christian, Höglinger, Günter U. · 2018 · Cell Death & Disease
- Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activationZhang, Qiu-Shuang, Heng, Yang, Yuan, Yu-He, Chen, Nai-Hong · 2017 · Toxicology Letters
- Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric α-SynucleinYu, Wai Haung, Dorado, Beatriz, Figueroa, Helen Yvette, Wang, Lili, Planel, Emmanuel, Cookson, Mark R., Clark, Lorraine N., Duff, Karen E. · 2009 · The American Journal of Pathology
- Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathiesSchildknecht, Stefan, Gerding, Hanne R., Karreman, Christiaan, Drescher, Malte, Lashuel, Hilal A., Outeiro, Tiago F., Di Monte, Donato A., Leist, Marcel · 2013 · Journal of Neurochemistry
- Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s DiseaseTóth, Gergely, Gardai, Shyra J., Zago, Wagner, Bertoncini, Carlos W., Cremades, Nunilo, Roy, Susan L., Tambe, Mitali A., Rochet, Jean-Christophe, Galvagnion, Celine, Skibinski, Gaia et al. · 2014 · PLoS ONE
- Toll-like receptors and their therapeutic potential in Parkinson’s disease and α-synucleinopathiesKouli, Antonina, Horne, C.B., Williams-Gray, C.H. · 2019 · Brain Behavior and Immunity
- A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptidesGallardo, Gilbert, Schlüter, Oliver M, Südhof, Thomas C · 2008 · Nature Neuroscience
- Mutant α-Synuclein Overexpression Mediates Early Proinflammatory ActivitySu, Xiaomin, Federoff, Howard J., Maguire-Zeiss, Kathleen A. · 2009 · Neurotoxicity Research
- Development and Characterization of a New Parkinson's Disease Model Resulting from Impaired AutophagyAhmed, Ishrat, Liang, Yideng, Schools, Sabitha, Dawson, Valina L., Dawson, Ted M., Savitt, Joseph M. · 2012 · The Journal of Neuroscience
- Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutationSimon, D.K., Pulst, S.M., Sutton, J.P., Browne, S.E., Beal, M.F., Johns, D.R. · 1999 · Neurology
- Brain Injection of α-Synuclein Induces Multiple Proteinopathies, Gliosis, and a Neuronal Injury MarkerSacino, Amanda N., Brooks, Mieu, McKinney, Alex B., Thomas, Michael A., Shaw, Gerry, Golde, Todd E., Giasson, Benoit I. · 2014 · The Journal of Neuroscience
- Neurofilament Light Chain as a Biomarker, and Correlation with Magnetic Resonance Imaging in Diagnosis of CNS-Related DisordersAlirezaei, Zahra, Pourhanifeh, Mohammad Hossein, Borran, Sarina, Nejati, Majid, Mirzaei, Hamed, Hamblin, Michael R. · 2020 · Molecular Neurobiology
- Intercellular Spread of Protein Aggregates in Neurodegenerative DiseaseDavis, Albert A., Leyns, Cheryl E.G., Holtzman, David M. · 2018 · Annual Review of Cell and Developmental Biology
- A New Treatment Strategy for Parkinson's Disease through the Gut–Brain Axis: The Glucagon-Like Peptide-1 Receptor PathwayKim, Dong Seok, Choi, Ho-Il, Wang, Yun, Luo, Yu, Hoffer, Barry J., Greig, Nigel H. · 2017 · Cell Transplantation
- Alpha-Synuclein: Mechanisms of Release and Pathology Progression in SynucleinopathiesBrás, Inês C., Outeiro, Tiago F. · 2021 · Cells
- Could a loss of α‐synuclein function put dopaminergic neurons at risk?Perez, Ruth G., Hastings, Teresa G. · 2004 · Journal of Neurochemistry
- Traffic at the intersection of neurotrophic factor signaling and neurodegenerationSalehi, Ahmad, Delcroix, Jean-Dominique, Mobley, William C. · 2003 · Trends in Neurosciences
- N-3 (Omega-3) Fatty Acids: Effects on Brain Dopamine Systems and Potential Role in the Etiology and Treatment of Neuropsychiatric DisordersHealy-Stoffel, Michelle, Levant, Beth · 2018 · CNS & Neurological Disorders - Drug Targets
- Neurotheranostics as Personalized MedicinesKevadiya, Bhavesh D., Ottemann, Brendan M., Thomas, Midhun Ben, Mukadam, Insiya, Nigam, Saumya, McMillan, JoEllyn, Gorantla, Santhi, Bronich, Tatiana K., Edagwa, Benson, Gendelman, Howard E. · 2019 · Advanced Drug Delivery Reviews
- Development, wiring and function of dopamine neuron subtypesGarritsen, Oxana, van Battum, Eljo Y., Grossouw, Laurens M., Pasterkamp, R. Jeroen · 2023 · Nature reviews. Neuroscience
- Does cellular iron dysregulation play a causative role in Parkinson’s disease?Kaur, Deepinder, Andersen, Julie · 2004 · Ageing Research Reviews