Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

Campfield, L. Arthur, Smith, Françoise J., Guisez, Yves, Devos, Rene, Burn, Paul·1995·Science

Cited by (157)

Items 101–157 of 157

  1. Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications
    Mark, Allyn L., Correia, Marcelo L. G., Rahmouni, Kamal, Haynes, William G. · 2002 · Journal of Hypertension
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    Satoh, Noriko, Ogawa, Yoshihiro, Katsuura, Goro, Hayase, Minoru, Tsuji, Tetsuo, Imagawa, Keiichi, Yoshimasa, Yasunao, Nishi, Shigeo, Hosoda, Kiminori, Nakao, Kazuwa · 1997 · Neuroscience Letters
  3. Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat
    Takaya, Kazuhiko, Ogawa, Yoshihiro, Hiraoka, Junko, Hosoda, Kiminori, Yamori, Yukio, Nakao, Kazuwa, Koletsky, Richard J. · 1996 · Nature Genetics
  4. Leptin Receptor Long-form Splice-variant Protein Expression in Neuron Cell Bodies of the Brain and Co-localization with Neuropeptide Y mRNA in the Arcuate Nucleus
    Baskin, Denis G., Schwartz, Michael W., Seeley, Randy J., Woods, Stephen C., Porte, Daniel, Breininger, John F., Jonak, Zoë, Schaefer, Jonathan, Krouse, Michael, Burghardt, Charles et al. · 1999 · Journal of Histochemistry & Cytochemistry
  5. Leptin Inhibits Directly Glucocorticoid Secretion by Normal Human and Rat Adrenal Gland**This work was supported by a grant from the Swiss National Science Foundation (No. 3100–050748.97/1).
    Pralong, François P., Roduit, Raphaël, Waeber, Gérard, Castillo, Einar, Mosimann, François, Thorens, Bernard, Gaillard, Rolf C. · 1998 · Endocrinology
  6. Leptin Modulates Behavioral Responses to Sweet Substances by Influencing Peripheral Taste Structures
    Shigemura, Noriatsu, Ohta, Rie, Kusakabe, Yuko, Miura, Hirohito, Hino, Akihiro, Koyano, Kiyoshi, Nakashima, Kiyohito, Ninomiya, Yuzo · 2004 · Endocrinology
  7. Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin
    Havel, Peter J., Uriu-Hare, Janet Y., Liu, Tina, Stanhope, Kimber L., Stern, Judith S., Keen, Carl L., Ahrén, Bo · 1998 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  8. Influence of body weight on bone mass, architecture and turnover
    Iwaniec, Urszula T, Turner, Russell T · 2016 · Journal of Endocrinology
  9. Anti-obesity therapy: from rainbow pills to polyagonists
    Müller, T.D., Clemmensen, C., Finan, B., DiMarchi, R.D., Tschöp, M.H. · 2018 · Pharmacological Reviews
  10. Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins
    Cusin, I, Zakrzewska, K E, Boss, O, Muzzin, P, Giacobino, J P, Ricquier, D, Jeanrenaud, B, Rohner-Jeanrenaud, F · 1998 · Diabetes
  11. Hypoxia and Adipocyte Physiology: Implications for Adipose Tissue Dysfunction in Obesity
    Trayhurn, Paul · 2014 · Annual Review of Nutrition
  12. Leptin Rapidly Lowers Food Intake and Elevates Metabolic Rates in Lean and ob/ob Mice ,
    Mistry, Anahita M., Swick, Andrew G., Romsos, Dale R. · 1997 · The Journal of Nutrition
  13. Obesity, diabetes and the central nervous system
    Porte Jr., D., Seeley, R. J., Woods, S. C., Baskin, D. G., Figlewicz, D. P., Schwartz, M. W. · 1998 · Diabetologia
  14. Role of melanocortin-4 receptors in mediating renal sympathoactivation to leptin and insulin
    Rahmouni, Kamal, Haynes, William G., Morgan, Donald A., Mark, Allyn L. · 2003 · The Journal of Neuroscience
  15. Developmental variations in environmental influences including endocrine disruptors on pubertal timing and neuroendocrine control: revision of human observations and mechanistic insight from rodents
    Parent, Anne-Simone, Franssen, Delphine, Fudvoye, Julie, Gérard, Arlette, Bourguignon, Jean-Pierre · 2015 · Frontiers in Neuroendocrinology
  16. Children with classic congenital adrenal hyperplasia have elevated serum leptin concentrations and insulin resistance: potential clinical implications.
    Charmandari, Evangelia, Weise, Martina, Bornstein, Stefan R., Eisenhofer, Graeme, Keil, Margaret F., Chrousos, George P., Merke, Deborah P. · 2002 · The Journal of Clinical Endocrinology & Metabolism
  17. Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes
    German, Jonathan P., Wisse, Brent E., Thaler, Joshua P., Oh-I, Shinsuke, Sarruf, David A., Ogimoto, Kayoko, Kaiyala, Karl J., Fischer, Jonathan D., Matsen, Miles E., Taborsky, Gerald J. et al. · 2010 · Diabetes
  18. Adult Type 3 Adenylyl Cyclase–Deficient Mice Are Obese
    Wang, Zhenshan, Li, Vicky, Chan, Guy C. K., Phan, Trongha, Nudelman, Aaron S., Xia, Zhengui, Storm, Daniel R. · 2009 · PLoS ONE
  19. Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats
    Morton, Gregory J., Niswender, Kevin D., Rhodes, Christopher J., Myers, Martin G., Blevins, James E., Baskin, Denis G., Schwartz, Michael W. · 2003 · Endocrinology
  20. Gene-Environment Interactions Controlling Energy and Glucose Homeostasis and the Developmental Origins of Obesity
    Bouret, Sebastien, Levin, Barry E., Ozanne, Susan E. · 2015 · Physiological Reviews
  21. Transplantation of Adipose Tissue Lacking Leptin Is Unable to Reverse the Metabolic Abnormalities Associated With Lipoatrophy
    Colombo, Carlo, Cutson, Jaime J., Yamauchi, Toshimasa, Vinson, Charles, Kadowaki, Takashi, Gavrilova, Oksana, Reitman, Marc L. · 2002 · Diabetes
  22. Region-Specific Reduction in Leptin-Induced Phosphorylation of Signal Transducer and Activator of Transcription-3 (STAT3) in the Rat Hypothalamus Is Associated with Leptin Resistance during Pregnancy
    Ladyman, S. R., Grattan, D. R. · 2004 · Endocrinology
  23. Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice
    Brown, Lynda M., Clegg, Deborah J., Benoit, Stephen C., Woods, Stephen C. · 2006 · Physiology & Behavior
  24. Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation
    Plum, Leona, Rother, Eva, Münzberg, Heike, Wunderlich, F. Thomas, Morgan, Donald A., Hampel, Brigitte, Shanabrough, Marya, Janoschek, Ruth, Könner, A. Christine, Alber, Jens et al. · 2007 · Cell Metabolism
  25. Dopamine is required for hyperphagia in Lepob/ob mice
    Szczypka, Mark S., Rainey, Mark A., Palmiter, Richard D. · 2000 · Nature Genetics
  26. Neuroendocrine profiles associated with energy intake, sleep, and stress in the night eating syndrome
    Allison, Kelly C., Ahima, Rexford S., O’Reardon, John P., Dinges, David F., Sharma, Vibhavasu, Cummings, David E., Heo, Moonseong, Martino, Nicole S., Stunkard, Albert J. · 2005 · The Journal of Clinical Endocrinology & Metabolism
  27. Control of Blood Pressure, Appetite, and Glucose by Leptin in Mice Lacking Leptin Receptors in Proopiomelanocortin Neurons
    do Carmo, Jussara M., da Silva, Alexandre A., Cai, Zhengwei, Lin, Shuying, Dubinion, John H., Hall, John E. · 2011 · Hypertension
  28. New targets to treat obesity and the metabolic syndrome
    Martin, Kathleen A., Mani, Mitra V., Mani, Arya · 2015 · European Journal of Pharmacology
  29. Fate of leptin after intracerebroventricular injection into the mouse brain
    Maness, Lawrence M., Kastin, Abba J., Farrell, Catherine L., Banks, William A. · 1998 · Endocrinology
  30. Intracellular Mechanisms Involved in Leptin Regulation of Sympathetic Outflow
    Rahmouni, Kamal, Haynes, William G., Morgan, Donald A., Mark, Allyn L. · 2003 · Hypertension
  31. Abnormal regulation of the leptin gene in the pathogenesis of obesity.
    Ioffe, Ella, Moon, Byoung, Connolly, Eileen, Friedman, Jeffrey M. · 1998 · Proceedings of the National Academy of Sciences
  32. A functional neuroimaging review of obesity, appetitive hormones and ingestive behavior
    Burger, Kyle S., Berner, Laura A. · 2014 · Physiology & Behavior
  33. Norepinephrine Is Required for Leptin Effects on Gene Expression in Brown and White Adipose Tissue<sup>1</sup>
    Commins, Scott P., Marsh, Donald J., Thomas, Steven A., Watson, Patricia M., Padgett, Mark A., Palmiter, Richard, Gettys, Thomas W. · 1999 · Endocrinology
  34. Hypothalamic, Metabolic, and Behavioral Responses to Pharmacological Inhibition of CNS Melanocortin Signaling in Rats
    Adage, Tiziana, Scheurink, Anton J. W., de Boer, Sietse F., de Vries, Koert, Konsman, Jan Pieter, Kuipers, Folkert, Adan, Roger A. H., Baskin, Denis G., Schwartz, Michael W., van Dijk, Gertjan · 2001 · The Journal of Neuroscience
  35. Preadipocyte Function and Aging: Links Between Age‐Related Changes in Cell Dynamics and Altered Fat Tissue Function
    Kirkland, James L., Dobson, Deborah E. · 1997 · Journal of the American Geriatrics Society
  36. Synaptic Plasticity in Energy Balance Regulation
    Horvath, Tamas L. · 2006 · Obesity
  37. Is Severe Obesity a Form of Addiction?: Rationale, Clinical Approach, and Controlled Clinical Trial
    Riva, Giuseppe, Bacchetta, Monica, Cesa, Gianluca, Conti, Sara, Castelnuovo, Gianluca, Mantovani, Fabrizia, Molinari, Enrico · 2006 · CyberPsychology &amp; Behavior
  38. Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-thyroid axis and feeding-related neurons in the arcuate nucleus
    Fekete, Csaba, Singru, Praful S., Sanchez, Edith, Sarkar, Sumit, Christoffolete, Marcelo A., Riberio, Rogerio S., Rand, William M., Emerson, Charles H., Bianco, Antonio C., Lechan, Ronald M. · 2006 · Endocrinology
  39. Vagal control of satiety and hormonal regulation of appetite
    Owyang, Chung, Heldsinger, Andrea · 2011 · Journal of Neurogastroenterology and Motility
  40. Food Cues and Obesity: Overpowering Hormones and Energy Balance Regulation
    Belfort-DeAguiar, Renata, Seo, Dongju · 2018 · Current Obesity Reports
  41. Insulin and NPY pathways and the control of GnRH function and puberty onset
    Pralong, François P. · 2010 · Molecular and Cellular Endocrinology
  42. The Role of Leptin in the Regulation of Energy Balance and Adiposity
    Van Dijk, Gertjan · 2001 · Journal of Neuroendocrinology
  43. Central leptin action improves skeletal muscle AKT, AMPK, and PGC1α activation by hypothalamic PI3K-dependent mechanism
    Roman, Erika A.F.R., Reis, Daniel, Romanatto, Talita, Maimoni, Denis, Ferreira, Eduardo A., Santos, Gustavo A., Torsoni, Adriana S., Velloso, Licio A., Torsoni, Marcio A. · 2010 · Molecular and Cellular Endocrinology
  44. 24‐Hour Changes in ACTH, Corticosterone, Growth Hormone, and Leptin Levels in Young Male Rats Subjected to Calorie Restriction
    Chacón, Fernando, Esquifino, Ana I., Perelló, Mario, Cardinali, Daniel P., Spinedi, Eduardo, Alvarez, María P. · 2005 · Chronobiology International
  45. Childhood Obesity: Immune Response and Nutritional Approaches
    Magrone, Thea, Jirillo, Emilio · 2015 · Frontiers in Immunology
  46. The genetics of obesity
    Damcott, Coleen M, Sack, Paul, Shuldiner, Alan R · 2003 · Endocrinology and Metabolism Clinics of North America
  47. The dual face of endogenous α-aminoketones: Pro-oxidizing metabolic weapons
    Bechara, Etelvino J.H., Dutra, Fernando, Cardoso, Vanessa E.S., Sartori, Adriano, Olympio, Kelly P.K., Penatti, Carlos A.A., Adhikari, Avishek, Assunção, Nilson A. · 2007 · Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology
  48. The relationship between the serum leptin concentrations of thyrotoxic patients during treatment and their total fat mass is different from that of normal subjects
    Zimmermann‐Belsing, Tina, Dreyer, Marianne, Juul Holst, Jens, Feldt‐Rasmussen, Ulla · 1998 · Clinical Endocrinology
  49. Behavioural treatment of the overweight patient
    Wadden, Thomas A., Sarwer, David B., Berkowitz, Robert I. · 1999 · Best Practice &amp; Research Clinical Endocrinology &amp; Metabolism
  50. Leptin is suppressed during infusion of recombinant human insulin-like growth factor I (rhIGF I) in normal rats
    Böni-Schnetzler, M., Hauri, C., Zapf, J. · 1999 · Diabetologia
  51. Differential Functions of Galanin Cell Groups in the Regulation of Eating and Body Weight <sup>a</sup>
    LEIBOWITZ, SARAH F. · 1998 · Annals of the New York Academy of Sciences
  52. The Neuronal Actions of Leptin and the Implications for Treating Alzheimer’s Disease
    Hamilton, Kirsty, Harvey, Jenni · 2021 · Pharmaceuticals
  53. Leptin Deficiency <i>Per Se</i> Dictates Body Composition and Insulin Action in <i>ob</i>/<i>ob</i> Mice
    Van Den Hoek, A. M., Teusink, B., Voshol, P. J., Havekes, L. M., Romijn, J. A., Pijl, H. · 2008 · Journal of Neuroendocrinology
  54. Emerging roles of leptin in Parkinson’s disease: Chronic inflammation, neuroprotection and more?
    Regensburger, Martin, Rasul Chaudhry, Shafqat, Yasin, Hammad, Zhao, Yining, Stadlbauer, Andreas, Buchfelder, Michael, Kinfe, Thomas · 2023 · Brain, Behavior, and Immunity
  55. Early and Strong Leptin Reduction Is Predictive for Long-Term Weight Loss during High-Protein, Low-Glycaemic Meal Replacement—A Subanalysis of the Randomised-Controlled ACOORH Trial
    Kempf, Kerstin, Röhling, Martin, Banzer, Winfried, Braumann, Klaus Michael, Halle, Martin, Schaller, Nina, McCarthy, David, Predel, Hans Georg, Schenkenberger, Isabelle, Tan, Susanne et al. · 2022 · Nutrients
  56. Central Control of Glucose Homeostasis
    Puglianiello, Antonella, Cianfarani, Stefano · 2006 · The Review of Diabetic Studies
  57. Eating Behavior
    Blundell, John E., Finlayson, Graham, Halford, Jason C. G. · 2009 · Clinical Obesity in Adults and Children