Cited by 5,688Advanced Causal Inference TechniquesStatistical Methods and Bayesian InferencePsychometric Methodologies and Testing

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Mediation Analysis

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MacKinnon, David P., Fairchild, Amanda J., Fritz, Matthew S.·2007·Annual Review of Psychology

DOI 10.1146/annurev.psych.58.110405.085542PMC PMC2819368

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Abstract

Abstract Mediating variables are prominent in psychological theory and research. A mediating variable transmits the effect of an independent variable on a dependent variable. Differences between mediating variables and confounders, moderators, and covariates are outlined. Statistical methods to assess mediation and modern comprehensive approaches are described. Future directions for mediation analysis are discussed.

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“Likewise, a change in outcome may result from changes in unique sets of potential mediators for different people (MacKinnon et al., 2007).”
Background
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Background
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Authors: MacKinnon, D. P., Fairchild, A. J., & Fritz, M. S.
Affiliations: Arizona State University (US)
ORCID: MacKinnon, David P.
Fairchild, Amanda J.
Fritz, Matthew S.
Venue: Annual Review of Psychology
Publisher: Annual Reviews
Published: 2007-01-01
Volume: 58
Issue: 1
Pages: 593-614
ISSN: 0066-4308 (ISSN-L)
1545-2085
DOI: 10.1146/annurev.psych.58.110405.085542
PMC: PMC2819368
OpenAlex: W4212838134
Cited by: 5,688
References: 102
Citations by year: 2026: 375 · 2025: 394 · 2024: 367 · 2023: 408 · 2022: 434 · 2021: 438 · 2020: 457 · 2019: 372 · 2018: 329 · 2017: 309 · 2016: 287 · 2015: 285 · 2014: 268 · 2013: 256 · 2012: 210
FWCI: 9.73
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Annual Review of Psychology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Scholar Commons (University of South Carolina) (submittedVersion)
Funders: National Institute on Drug Abuse (DA 09757, R01DA009757, R37DA009757)
Topics: Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
Keywords: mediation analysis, mediators, confounders, moderators, covariates, causal inference
MeSH terms: Analysis of Variance, Humans, Longitudinal Studies, Mathematical Computing, Models, Psychological, Psychological Theory, Models, Statistical, Causality, Effect Modifier, Epidemiologic, Treatment Outcome, Biomedical Research

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