MicroRNAs in Development and Disease

Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.

Bachman, K. E., Herman, J. G., Corn, P. G., Merlo, A., Costello, J., Cavenee, W. K., Baylin, S. B., & Graff, J. R. (1999) · PubMed · Cited by 358

MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths

Sayed, D., Rane, S., Lypowy, J., He, M., Chen, I.-Y., Vashistha, H., Yan, L., Malhotra, A., Vatner, D., & Abdellatif, M. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-02-0159 · Cited by 355

Up‐regulated microRNA‐143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression†

Zhang, X., Liu, S., Hu, T., Liu, S., He, Y., & Sun, S. (2009) · Hepatology · doi:10.1002/hep.23008 · Cited by 355

Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells

Juan, A. H., Kumar, R. M., Marx, J. G., Young, R. A., & Sartorelli, V. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.08.008 · Cited by 354

Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells

Venturini, L., Battmer, K., Castoldi, M., Schultheis, B., Hochhaus, A., Muckenthaler, M. U., Ganser, A., Eder, M., & Scherr, M. (2007) · Blood · doi:10.1182/blood-2006-09-045104 · Cited by 353

Micro RNA 145 Targets the Insulin Receptor Substrate-1 and Inhibits the Growth of Colon Cancer Cells

Shi, B., Sepp-Lorenzino, L., Prisco, M., Linsley, P., deAngelis, T., & Baserga, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702806200 · Cited by 353

MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer

Yang, N., Kaur, S., Volinia, S., Greshock, J., Lassus, H., Hasegawa, K., Liang, S., Leminen, A., Deng, S., Smith, L., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-1954 · Cited by 352

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

Höck, J., Weinmann, L., Ender, C., Rüdel, S., Kremmer, E., Raabe, M., Urlaub, H., & Meister, G. (2007) · The EMBO Reports · doi:10.1038/sj.embor.7401088 · Cited by 352

MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse

Lynn, F. C., Skewes-Cox, P., Kosaka, Y., McManus, M. T., Harfe, B. D., & German, M. S. (2007) · Diabetes · doi:10.2337/db07-0175 · Cited by 351

MicroRNA-9 Controls the Expression of Granuphilin/Slp4 and the Secretory Response of Insulin-producing Cells

Plaisance, V., Abderrahmani, A., Perret-Menoud, V., Jacquemin, P., Lemaigre, F., & Regazzi, R. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601225200 · Cited by 350

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

Knuesel, M. T., Meyer, K. D., Bernecky, C., & Taatjes, D. J. (2009) · Genes & Development · doi:10.1101/gad.1767009 · Cited by 350

Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

Shi, S., Yu, L., Chiu, C., Sun, Y., Chen, J., Khitrov, G., Merkenschlager, M., Holzman, L. B., Zhang, W., Mundel, P., et al. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2008030312 · Cited by 349

A GATA-1-regulated microRNA locus essential for erythropoiesis

Dore, L. C., Amigo, J. D., dos Santos, C. O., Zhang, Z., Gai, X., Tobias, J. W., Yu, D., Klein, A. M., Dorman, C., Wu, W., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712312105 · Cited by 347

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

Bhat-Nakshatri, P., Wang, G., Collins, N. R., Thomson, M. J., Geistlinger, T. R., Carroll, J. S., Brown, M., Hammond, S., Srour, E. F., Liu, Y., et al. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp500 · Cited by 346

Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126

Kuhnert, F., Mancuso, M. R., Hampton, J., Stankunas, K., Asano, T., Chen, C.-Z., & Kuo, C. J. (2008) · Development · doi:10.1242/dev.029736 · Cited by 344

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., & Huttner, W. B. (2008) · Development · doi:10.1242/dev.025080 · Cited by 343

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

O’Carroll, D., Mecklenbrauker, I., Das, P. P., Santana, A., Koenig, U., Enright, A. J., Miska, E. A., & Tarakhovsky, A. (2007) · Genes & Development · doi:10.1101/gad.1565607 · Cited by 343

MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance

Moriyama, T., Ohuchida, K., Mizumoto, K., Yu, J., Sato, N., Nabae, T., Takahata, S., Toma, H., Nagai, E., & Tanaka, M. (2009) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-08-0592 · Cited by 342

Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism

Ouchi, N., Oshima, Y., Ohashi, K., Higuchi, A., Ikegami, C., Izumiya, Y., & Walsh, K. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803440200 · Cited by 338

RNA editing of human microRNAs

Blow, M. J., Grocock, R. J., van Dongen, S., Enright, A. J., Dicks, E., Futreal, P. A., Wooster, R., & Stratton, M. R. (2006) · Genome Biology · doi:10.1186/gb-2006-7-4-r27 · Cited by 338

A functional study of miR-124 in the developing neural tube

Cao, X., Pfaff, S. L., & Gage, F. H. (2007) · Genes & Development · doi:10.1101/gad.1519207 · Cited by 336

Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

Michlewski, G., Guil, S., Semple, C. A., & Cáceres, J. F. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.10.013 · Cited by 335

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

Ferretti, E., De Smaele, E., Miele, E., Laneve, P., Po, A., Pelloni, M., Paganelli, A., Di Marcotullio, L., Caffarelli, E., Screpanti, I., et al. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.172 · Cited by 332

Chromosomal and Gene Amplification in Diffuse Large B-Cell Lymphoma

Rao, P. H., Houldsworth, J., Dyomina, K., Parsa, N. Z., Cigudosa, J. C., Louie, D. C., Popplewell, L., Offit, K., Jhanwar, S. C., & Chaganti, R. S. K. (1998) · Blood · doi:10.1182/blood.v92.1.234.413k22_234_240 · Cited by 331

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

Fujita, Y., Kojima, K., Hamada, N., Ohhashi, R., Akao, Y., Nozawa, Y., Deguchi, T., & Ito, M. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.09.086 · Cited by 331

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

Cheng, Y., Zhu, P., Yang, J., Liu, X., Dong, S., Wang, X., Chun, B., Zhuang, J., & Zhang, C. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq082 · Cited by 331

The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response

Castellano, L., Giamas, G., Jacob, J., Coombes, R. C., Lucchesi, W., Thiruchelvam, P., Barton, G., Jiao, L. R., Wait, R., Waxman, J., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906947106 · Cited by 329

Dysregulation of miRNA 181b in the temporal cortex in schizophrenia

Beveridge, N. J., Tooney, P. A., Carroll, A. P., Gardiner, E., Bowden, N., Scott, R. J., Tran, N., Dedova, I., & Cairns, M. J. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn005 · Cited by 328

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

Davis, B. N., Hilyard, A. C., Nguyen, P. H., Lagna, G., & Hata, A. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808788200 · Cited by 327

MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo

Liu, B., Peng, X.-C., Zheng, X.-L., Wang, J., & Qin, Y.-W. (2009) · Lung Cancer · doi:10.1016/j.lungcan.2009.01.010 · Cited by 326

MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206

Rosenberg, M. I., Georges, S. A., Asawachaicharn, A., Analau, E., & Tapscott, S. J. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200603039 · Cited by 324

An Evolutionarily Conserved Mechanism for MicroRNA-223 Expression Revealed by MicroRNA Gene Profiling

Fukao, T., Fukuda, Y., Kiga, K., Sharif, J., Hino, K., Enomoto, Y., Kawamura, A., Nakamura, K., Takeuchi, T., & Tanabe, M. (2007) · Cell · doi:10.1016/j.cell.2007.02.048 · Cited by 323

Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease

Harvey, S. J., Jarad, G., Cunningham, J., Goldberg, S., Schermer, B., Harfe, B. D., McManus, M. T., Benzing, T., & Miner, J. H. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2008020233 · Cited by 320

EBV MicroRNAs in Primary Lymphomas and Targeting of CXCL-11 by ebv-mir-BHRF1-3

Xia, T., O’Hara, A. J., Araújo, I., Barreto, J., Carvalho, E. G., Sapucaia, J. B., Ramos, J. C., Luz, E., Pedroso, C., Manrique, M., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-5126 · Cited by 319

Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation

Thermann, R., & Hentze, M. W. (2007) · Nature · doi:10.1038/nature05878 · Cited by 316

Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1

Karsunky, H., Zeng, H., Schmidt, T., Zevnik, B., Kluge, R., Schmid, K. W., Dührsen, U., & Möröy, T. (2002) · Nature Genetics · doi:10.1038/ng831 · Cited by 315

MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand

Sayed, D., He, M., Hong, C., Gao, S., Rane, S., Yang, Z., & Abdellatif, M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.109207 · Cited by 315

Identification of Cellular Genes Targeted by KSHV-Encoded MicroRNAs

Samols, M. A., Skalsky, R. L., Maldonado, A. M., Riva, A., Lopez, M. C., Baker, H. V., & Renne, R. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030065 · Cited by 315

MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary

Leucht, C., Stigloher, C., Wizenmann, A., Klafke, R., Folchert, A., & Bally-Cuif, L. (2008) · Nature Neuroscience · doi:10.1038/nn.2115 · Cited by 313

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

Yu, J.-Y., Chung, K.-H., Deo, M., Thompson, R. C., & Turner, D. L. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.06.002 · Cited by 312

miR-200 Regulates PDGF-D-Mediated Epithelial–Mesenchymal Transition, Adhesion, and Invasion of Prostate Cancer Cells

Kong, D., Li, Y., Wang, Z., Banerjee, S., Ahmad, A., Kim, H.-R. C., & Sarkar, F. H. (2009) · Stem Cells · doi:10.1002/stem.101 · Cited by 311

RNA editing of a miRNA precursor: FIGURE 1.

LUCIANO, D. J., MIRSKY, H., VENDETTI, N. J., & MAAS, S. (2004) · RNA · doi:10.1261/rna.7350304 · Cited by 311

MicroRNA-Mediated Control of Cell Fate in Megakaryocyte-Erythrocyte Progenitors

Lu, J., Guo, S., Ebert, B. L., Zhang, H., Peng, X., Bosco, J., Pretz, J., Schlanger, R., Wang, J. Y., Mak, R. H., et al. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.03.012 · Cited by 310

Epstein-Barr Virus Latent Membrane Protein 1 Induces Cellular MicroRNA miR-146a, a Modulator of Lymphocyte Signaling Pathways

Cameron, J. E., Yin, Q., Fewell, C., Lacey, M., McBride, J., Wang, X., Lin, Z., Schaefer, B. C., & Flemington, E. K. (2008) · Journal of Virology · doi:10.1128/jvi.02136-07 · Cited by 310

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics

Bisson, I., & Prowse, D. M. (2009) · Cell Research · doi:10.1038/cr.2009.43 · Cited by 308

MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality

Gramantieri, L., Fornari, F., Ferracin, M., Veronese, A., Sabbioni, S., Calin, G. A., Grazi, G. L., Croce, C. M., Bolondi, L., & Negrini, M. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0092 · Cited by 308

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

Wakiyama, M., Takimoto, K., Ohara, O., & Yokoyama, S. (2007) · Genes & Development · doi:10.1101/gad.1566707 · Cited by 307

Characterization and Identification of MicroRNA Core Promoters in Four Model Species

Zhou, X., Ruan, J., Wang, G., & Zhang, W. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030037 · Cited by 306

Role of MicroRNA-155 at Early Stages of Hepatocarcinogenesis Induced by Choline-Deficient and Amino Acid–Defined Diet in C57BL/6 Mice†

Wang, B., Majumder, S., Nuovo, G., Kutay, H., Volinia, S., Patel, T., Schmittgen, T. D., Croce, C., Ghoshal, K., & Jacob, S. T. (2009) · Hepatology · doi:10.1002/hep.23100 · Cited by 304

Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy

Sarasin-Filipowicz, M., Krol, J., Markiewicz, I., Heim, M. H., & Filipowicz, W. (2009) · Nature Medicine · doi:10.1038/nm.1902 · Cited by 304

An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice

Lewis, M. A., Quint, E., Glazier, A. M., Fuchs, H., De Angelis, M. H., Langford, C., van Dongen, S., Abreu-Goodger, C., Piipari, M., Redshaw, N., et al. (2009) · Nature Genetics · doi:10.1038/ng.369 · Cited by 302

MicroRNA-298 and MicroRNA-328 Regulate Expression of Mouse β-Amyloid Precursor Protein-converting Enzyme 1

Boissonneault, V., Plante, I., Rivest, S., & Provost, P. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m807530200 · Cited by 301

MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila

Li, Y., Wang, F., Lee, J.-A., & Gao, F.-B. (2006) · Genes & Development · doi:10.1101/gad.1466306 · Cited by 301

MicroRNA miR-155 is a biomarker of early pancreatic neoplasia

Habbe, N., Koorstra, J.-B. M., Mendell, J. T., Offerhaus, G. J., Ryu, J. K., Feldmann, G., Mullendore, M. E., Goggins, M. G., Hong, S.-M., & Maitra, A. (2009) · Cancer Biology & Therapy · doi:10.4161/cbt.8.4.7338 · Cited by 300

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression

Crist, C. G., Montarras, D., Pallafacchina, G., Rocancourt, D., Cumano, A., Conway, S. J., & Buckingham, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900210106 · Cited by 299

Reciprocal Regulation of Myocardial microRNAs and Messenger RNA in Human Cardiomyopathy and Reversal of the microRNA Signature by Biomechanical Support

Matkovich, S. J., Van Booven, D. J., Youker, K. A., Torre-Amione, G., Diwan, A., Eschenbacher, W. H., Dorn, L. E., Watson, M. A., Margulies, K. B., & Dorn, G. W. (2009) · Circulation · doi:10.1161/circulationaha.108.813576 · Cited by 299

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

Ho, J., Ng, K. H., Rosen, S., Dostal, A., Gregory, R. I., & Kreidberg, J. A. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2008020162 · Cited by 297

miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator

Lagos, D., Pollara, G., Henderson, S., Gratrix, F., Fabani, M., Milne, R. S. B., Gotch, F., & Boshoff, C. (2010) · Nature Cell Biology · doi:10.1038/ncb2054 · Cited by 296

Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic mice

Costinean, S., Sandhu, S. K., Pedersen, I. M., Tili, E., Trotta, R., Perrotti, D., Ciarlariello, D., Neviani, P., Harb, J., Kauffman, L. R., et al. (2009) · Blood · doi:10.1182/blood-2009-05-220814 · Cited by 292

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

Garofalo, M., Quintavalle, C., Di Leva, G., Zanca, C., Romano, G., Taccioli, C., Liu, C. G., Croce, C. M., & Condorelli, G. (2008) · Oncogene · doi:10.1038/onc.2008.6 · Cited by 289

Specific Interaction of Eukaryotic Translation Initiation Factor 3 with the 5′ Nontranslated Regions of Hepatitis C Virus and Classical Swine Fever Virus RNAs

Sizova, D. V., Kolupaeva, V. G., Pestova, T. V., Shatsky, I. N., & Hellen, C. U. T. (1998) · Journal of Virology · doi:10.1128/jvi.72.6.4775-4782.1998 · Cited by 288

Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma

Park, J.-K., Lee, E. J., Esau, C., & Schmittgen, T. D. (2009) · Pancreas · doi:10.1097/mpa.0b013e3181ba82e1 · Cited by 287

Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells

Chen, R., Alvero, A. B., Silasi, D. A., Kelly, M. G., Fest, S., Visintin, I., Leiser, A., Schwartz, P. E., Rutherford, T., & Mor, G. (2008) · Oncogene · doi:10.1038/onc.2008.112 · Cited by 287

bic, a Novel Gene Activated by Proviral Insertions in Avian Leukosis Virus-Induced Lymphomas, Is Likely To Function through Its Noncoding RNA

Tam, W., Ben-Yehuda, D., & Hayward, W. S. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.3.1490 · Cited by 285

Downregulation of microRNAs‐143 and ‐145 in B‐cell malignancies

Akao, Y., Nakagawa, Y., Kitade, Y., Kinoshita, T., & Naoe, T. (2007) · Cancer Science · doi:10.1111/j.1349-7006.2007.00618.x · Cited by 285

MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer

Ng, E. K. O., Tsang, W. P., Ng, S. S. M., Jin, H. C., Yu, J., Li, J. J., Röcken, C., Ebert, M. P. A., Kwok, T. T., & Sung, J. J. Y. (2009) · British Journal of Cancer · doi:10.1038/sj.bjc.6605195 · Cited by 284

Hypermethylation of let-7a-3 in Epithelial Ovarian Cancer Is Associated with Low Insulin-like Growth Factor-II Expression and Favorable Prognosis

Lu, L., Katsaros, D., Rigault de la Longrais, I. A., Sochirca, O., & Yu, H. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-2544 · Cited by 282

Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice

Raveche, E. S., Salerno, E., Scaglione, B. J., Manohar, V., Abbasi, F., Lin, Y.-C., Fredrickson, T., Landgraf, P., Ramachandra, S., Huppi, K., et al. (2007) · Blood · doi:10.1182/blood-2007-02-071225 · Cited by 281

The miR-17 ∼ 92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

Uziel, T., Karginov, F. V., Xie, S., Parker, J. S., Wang, Y.-D., Gajjar, A., He, L., Ellison, D., Gilbertson, R. J., Hannon, G., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809579106 · Cited by 278

Identification of glucose-regulated miRNAs from pancreatic β cells reveals a role for miR-30d in insulin transcription

Tang, X., Muniappan, L., Tang, G., & Özcan, S. (2009) · RNA · doi:10.1261/rna.1211209 · Cited by 276

A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer

Hu, X., Macdonald, D. M., Huettner, P. C., Feng, Z., El Naqa, I. M., Schwarz, J. K., Mutch, D. G., Grigsby, P. W., Powell, S. N., & Wang, X. (2009) · Gynecologic Oncology · doi:10.1016/j.ygyno.2009.05.022 · Cited by 275

MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers

Akao, Y., Nakagawa, Y., & Naoe, T. (2006) · Oncology Reports · doi:10.3892/or.16.4.845 · Cited by 275

Accelerated Onset and Increased Incidence of Ventricular Arrhythmias Induced by Ischemia in Cx43-Deficient Mice

Lerner, D. L., Yamada, K. A., Schuessler, R. B., & Saffitz, J. E. (2000) · Circulation · doi:10.1161/01.cir.101.5.547 · Cited by 273

Long-Lasting Novelty-Induced Neuronal Reverberation during Slow-Wave Sleep in Multiple Forebrain Areas

Ribeiro, S., Gervasoni, D., Soares, E. S., Zhou, Y., Lin, S.-C., Pantoja, J., Lavine, M., & Nicolelis, M. A. L. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020024 · Cited by 272

MicroRNA-1/206 Targets c-Met and Inhibits Rhabdomyosarcoma Development

Yan, D., Dong, X. D., Chen, X., Wang, L., Lu, C., Wang, J., Qu, J., & Tu, L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.020511 · Cited by 271

Genome‐wide microRNA expression profiling in renal cell carcinoma: significant down‐regulation of miR‐141 and miR‐200c

Nakada, C., Matsuura, K., Tsukamoto, Y., Tanigawa, M., Yoshimoto, T., Narimatsu, T., Nguyen, L., Hijiya, N., Uchida, T., Sato, F., et al. (2008) · The Journal of Pathology · doi:10.1002/path.2437 · Cited by 269

Elevated Akt Activity Protects the Prostate Cancer Cell Line LNCaP from TRAIL-induced Apoptosis

Nesterov, A., Lu, X., Johnson, M., Miller, G. J., Ivashchenko, Y., & Kraft, A. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005196200 · Cited by 269

Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit?

Lewis-Wambi, J. S., & Jordan, V. C. (2009) · Breast Cancer Research · doi:10.1186/bcr2255 · Cited by 267

Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13.

Seraj, M. J., Samant, R. S., Verderame, M. F., & Welch, D. R. (2000) · PubMed · Cited by 265

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA

Lei, X., Bai, Z., Ye, F., Xie, J., Kim, C.-G., Huang, Y., & Gao, S.-J. (2010) · Nature Cell Biology · doi:10.1038/ncb2019 · Cited by 264

The Role of microRNA-221 and microRNA-222 in Androgen-Independent Prostate Cancer Cell Lines

Sun, T., Wang, Q., Balk, S., Brown, M., Lee, G.-S. M., & Kantoff, P. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-4112 · Cited by 263

MicroRNA-26a Targets the Histone Methyltransferase Enhancer of Zeste homolog 2 during Myogenesis

Wong, C. F., & Tellam, R. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709614200 · Cited by 261

Comparative sequence analysis reveals an intricate network among REST, CREBand miRNA in mediating neuronal gene expression

Wu, J., & Xie, X. (2006) · Genome Biology · doi:10.1186/gb-2006-7-9-r85 · Cited by 260

The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation

Taulli, R., Bersani, F., Foglizzo, V., Linari, A., Vigna, E., Ladanyi, M., Tuschl, T., & Ponzetto, C. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38075 · Cited by 260

Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer

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Brain Expressed microRNAs Implicated in Schizophrenia Etiology

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Retinoic Acid Receptor Antagonists Inhibit miR-10a Expression and Block Metastatic Behavior of Pancreatic Cancer

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MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines

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miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines

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Role of the miR‐106b‐25 microRNA cluster in hepatocellular carcinoma

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MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

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Peroxisome Proliferator-Activated Receptor α Regulates a MicroRNA-Mediated Signaling Cascade Responsible for Hepatocellular Proliferation

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Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation

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Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathway

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Expression of islet-specific microRNAs during human pancreatic development

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MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets

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Common micro‐RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia

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An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

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miRNA expression profiles in chronic lymphocytic and acute lymphocytic leukemia

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snoRNA, a Novel Precursor of microRNA in Giardia lamblia

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The Inhibition of the Highly Expressed Mir-221 and Mir-222 Impairs the Growth of Prostate Carcinoma Xenografts in Mice

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MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

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Post-transcriptional expression regulation in the yeast Saccharomyces cerevisiae on a genomic scale

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HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR

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MicroRNA expression during chick embryo development

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Widespread Estrogen-Dependent Repression of microRNAs Involved in Breast Tumor Cell Growth

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Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1

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MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells

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Let-7 Prevents Early Cancer Progression by Suppressing Expression of the Embryonic Gene HMGA2

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MiR-15a and MiR-16 Control Bmi-1 Expression in Ovarian Cancer

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miRNA expression in the failing human heart: Functional correlates

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MicroRNA-193b Represses Cell Proliferation and Regulates Cyclin D1 in Melanoma

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Cellular microRNA expression correlates with susceptibility of monocytes/macrophages to HIV-1 infection

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The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient

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miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors

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Expression of microRNA‐221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrence

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miR-198 Inhibits HIV-1 Gene Expression and Replication in Monocytes and Its Mechanism of Action Appears To Involve Repression of Cyclin T1

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Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation

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Distinctive Patterns of MicroRNA Expression Associated with Karyotype in Acute Myeloid Leukaemia

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Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth

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Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element

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Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration

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MiR-107 and MiR-185 Can Induce Cell Cycle Arrest in Human Non Small Cell Lung Cancer Cell Lines

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Postsynaptic Abnormalities at the Neuromuscular Junctions of Utrophin-deficient Mice

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MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a

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Liver-Specific MicroRNA miR-122 Enhances the Replication of Hepatitis C Virus in Nonhepatic Cells

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MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G

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The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors

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Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia

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Melanoma MicroRNA Signature Predicts Post-Recurrence Survival

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Lack of BIC and microRNA miR‐155 expression in primary cases of Burkitt lymphoma

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HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

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Acceleration of muscle regeneration by local injection of muscle‐specific microRNAs in rat skeletal muscle injury model

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MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation

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MicroRNA-9 Modulates Cajal–Retzius Cell Differentiation by Suppressing Foxg1 Expression in Mouse Medial Pallium

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Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency by Virus-Encoded MicroRNAs That Target Rta and the Cellular Rbl2-DNMT Pathway

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Onco‐miR‐155 targets SHIP1 to promote TNFα‐dependent growth of B cell lymphomas

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Microrna-221 and Microrna-222 Modulate Differentiation and Maturation of Skeletal Muscle Cells

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Combinatorial function of ETS transcription factors in the developing vasculature

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The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications

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Integrin β3 expression is regulated by let-7a miRNA in malignant melanoma

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Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

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MicroRNAs can regulate human APP levels

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MicroRNA gene expression in the mouse inner ear

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Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs

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MicroRNA‐15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanoma

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A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 Is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A

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Targeted Inactivation of Serum Response Factor in the Developing Heart Results in Myocardial Defects and Embryonic Lethality

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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 (LMP1) Induces the Expression of the Cellular MicroRNA miR-146a

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miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis

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MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4

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HIV-1 encoded candidate micro-RNAs and their cellular targets

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miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2

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MicroRNA-125a represses cell growth by targeting HuR in breast cancer

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Ago–TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

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Drosophila Argonaute1 and Argonaute2 Employ Distinct Mechanisms for Translational Repression

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A Novel Role of MicroRNA in Late Preconditioning: Upregulation of Endothelial Nitric Oxide Synthase and Heat Shock Protein 70

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Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion

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MicroRNA‐9 inhibits ovarian cancer cell growth through regulation of NF‐κB1

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Epstein-Barr Virus-Induced miR-155 Attenuates NF-κB Signaling and Stabilizes Latent Virus Persistence

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Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma

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T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC

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microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs

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c-Myb Is Critical for B Cell Development and Maintenance of Follicular B Cells

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Characterization of Epstein-Barr Virus miRNAome in Nasopharyngeal Carcinoma by Deep Sequencing

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MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease

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MicroRNA 133B targets pro-survival molecules MCL-1 and BCL2L2 in lung cancer

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