Centella asiatica(L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential

Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function

Howes, M. R., & Houghton, P. J. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00128-x · Cited by 443 · see citing works

Phenolic contents and antioxidant activity of some food and medicinal plants

Bajpai, M., Pande, A., Tewari, S. K., & Prakash, D. (2005) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637480500146606 · Cited by 418 · see citing works

In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method.

Mr, Z., Rain, A. N., Ar, B., Adlin, A., Norazah, A., & Zakiah, I. (2005) · PubMed · Cited by 357 · see citing works

Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats

Veerendra Kumar, M. H., & Gupta, Y. K. (2002) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(01)00394-4 · Cited by 261 · see citing works

Effect of Centella asiatica on pentylenetetrazole-induced kindling, cognition and oxidative stress in rats

Gupta, Y. K., Kumar, M., & Srivastava, A. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)01044-4 · Cited by 253 · see citing works

Effect of <i>Centella asiatica</i> on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats

Veerendra Kumar, M., & Gupta, Y. (2003) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2003.03842.x · Cited by 249 · see citing works

Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity

Mukherjee, P. K., Venkatesan, K., & Houghton, P. J. (2007) · Phytotherapy Research · doi:10.1002/ptr.2224 · Cited by 228 · see citing works

Effects of Centella asiatica extract on dermal wound healing in rats.

Suguna, L., Sivakumar, P., & Chandrakasan, G. (1996) · PubMed · Cited by 183 · see citing works

Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica

Wattanathorn, J., Mator, L., Muchimapura, S., Tong-un, T., Pasurivong, O., Piyawatkul, N., Yimtae, K., Sripanidkulchai, B., & Singkhoraard, J. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.11.038 · Cited by 179 · see citing works

<i>Centella asiatica</i> extract selectively decreases amyloid <i>β</i> levels in hippocampus of Alzheimer's disease animal model

Dhanasekaran, M., Holcomb, L. A., Hitt, A. R., Tharakan, B., Porter, J. W., Young, K. A., & Manyam, B. V. (2009) · Phytotherapy Research · doi:10.1002/ptr.2405 · Cited by 175 · see citing works

Anti-herpes simplex virus activities of crude water extracts of Thai Medicinal Plants

Yoosook, C., Bunyapraphatsara, N., Boonyakiat, Y., & Kantasuk, C. (2000) · Phytomedicine · doi:10.1016/s0944-7113(00)80068-9 · Cited by 175 · see citing works

Larvicidal and adulticidal activities of some medicinal plants against the Malarial Vector, Anopheles stephensi (Liston)

Senthilkumar, N., Varma, P., & Gurusubramanian, G. (2008) · Parasitology Research · doi:10.1007/s00436-008-1180-4 · Cited by 172 · see citing works

Effects of traditionally used anxiolytic botanicals on enzymes of the γ-aminobutyric acid (GABA) systemThis article is one of a selection of papers published in this special issue (part 1 of 2) on the Safety and Efficacy of Natural Health Products.

Awad, R., Levac, D., Cybulska, P., Merali, Z., Trudeau, V. L., & Arnason, J. T. (2007) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y07-083 · Cited by 171 · see citing works

Evaluation of anxiolytic properties of Gotukola – (Centella asiatica) extracts and asiaticoside in rat behavioral models

Wijeweera, P., Arnason, J. T., Koszycki, D., & Merali, Z. (2006) · Phytomedicine · doi:10.1016/j.phymed.2006.01.011 · Cited by 171 · see citing works

Asiatic acid, a pentacyclic triterpene from <i>Centella asiatica</i>, is neuroprotective in a mouse model of focal cerebral ischemia

Krishnamurthy, R. G., Senut, M., Zemke, D., Min, J., Frenkel, M. B., Greenberg, E. J., Yu, S., Ahn, N., Goudreau, J., Kassab, M., et al. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22071 · Cited by 155 · see citing works

<i>Centella asiatica</i> accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro

Soumyanath, A., Zhong, Y.-P., Yu, X., Bourdette, D., Koop, D. R., Gold, S. A., & Gold, B. G. (2005) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.57.9.0018 · Cited by 150 · see citing works

Centella asiatica treatment during postnatal period enhances learning and memory in mice

Rao, B. S. S., Chetana, M., & Devi, P. U. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.07.019 · Cited by 148 · see citing works

Effects of Centella asiatica on ethanol induced gastric mucosal lesions in rats

Cheng, C. L., & Koo, M. W. L. (2000) · Life Sciences · doi:10.1016/s0024-3205(00)00848-1 · Cited by 147 · see citing works

The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats

Cheng, C. L., Guo, J., Luk, J. M., & Koo, M. W. L. (2004) · Life Sciences · doi:10.1016/j.lfs.2003.09.055 · Cited by 142 · see citing works

Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhanced expression of p53 in HepG2 human hepatoma cells

Lee, Y. S., Jin, D., Kwon, E. J., Park, S. H., Lee, E.-S., Jeong, T. C., Nam, D. H., Huh, K. Y., & Kim, J. (2002) · Cancer Letters · doi:10.1016/s0304-3835(02)00260-4 · Cited by 140 · see citing works

Medicinal Foodstuffs. XXVII. Saponin Constituents of Gotu Kola (2): Structures of New Ursane- and Oleanane-Type Triterpene Oligoglycosides, Centellasaponins B, C, and D, from Centella asiatica Cultivated in Sri Lanka.

Matsuda, H., Morikawa, T., Ueda, H. R., & Yoshikawa, M. (2001) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.49.1368 · Cited by 133 · see citing works

Antiproliferative Constituents from Umbelliferae Plants VII. Active Triterpenes and Rosmarinic Acid from Centella asiatica

Yoshida, M., Fuchigami, M., Nagao, T., Okabe, H., Matsunaga, K., Takata, J., Karube, Y., Tsuchihashi, R., Kinjo, J., Mihashi, K., et al. (2005) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.28.173 · Cited by 130 · see citing works

Neuroprotective Effects ofCentella asiaticaagainst Intracerebroventricular Colchicine-Induced Cognitive Impairment and Oxidative Stress

Kumar, A., Dogra, S., & Prakash, A. K. (2009) · International Journal of Alzheimer s Disease · doi:10.4061/2009/972178 · Cited by 129 · see citing works

Anti-oxidant activity of Centella asiatica on lymphoma-bearing mice

Jayashree, G., Kurup Muraleedhara, G., Sudarslal, S., & Jacob, V. B. (2003) · Fitoterapia · doi:10.1016/s0367-326x(03)00121-7 · Cited by 129 · see citing works

In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins

Sampson, J., Raman, A., Karlsen, G., Navsaria, H. A., & Leigh, I. M. (2001) · Phytomedicine · doi:10.1078/0944-7113-00032 · Cited by 125 · see citing works

Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats

Haleagrahara, N., & Ponnusamy, K. (2010) · The Journal of Toxicological Sciences · doi:10.2131/jts.35.41 · Cited by 123 · see citing works

Chemical Composition and Antibacterial Activity of the Essential Oil ofCentella asiatica. Growing in South Africa

Oyedeji, A. O., & Afolayan, A. J. (2005) · Pharmaceutical Biology · doi:10.1080/13880200590928843 · Cited by 118 · see citing works

Protective effect of Centella asiatica on antioxidant tissue defense system against adriamycin induced cardiomyopathy in rats

Gnanapragasam, A., Ebenezar, K. K., Sathish, V., Govindaraju, P., & Devaki, T. (2004) · Life Sciences · doi:10.1016/j.lfs.2004.09.009 · Cited by 114 · see citing works

Asiatic acid derivatives protect cultured cortical neurons from glutamate-induced excitotoxicity.

Mk, L., Kim, Sung, S. H., Lím, D., Kim, H., Choi, H. J., Hk, P., Je, S., & Yc, K. (2000) · PubMed · Cited by 111 · see citing works

Characterisation of antioxidative activities of various extracts of Centella asiatica (L) Urban

Hamid, A. A., Shah, Z. M., Muse, R., & Mohamed, S. (2002) · Food Chemistry · doi:10.1016/s0308-8146(01)00384-3 · Cited by 104 · see citing works

Centella asiatica (Linn.) Urban — A Review

Jamil, S. S., Nizami, Q., & Salam, M. (2007) · Cited by 104 · see citing works

Molecular design of tyrosinase inhibitors: A critical review of promising novel inhibitors from synthetic origins

Khan, M. T. H. (2007) · Pure and Applied Chemistry · doi:10.1351/pac200779122277 · Cited by 91 · see citing works

Untitled work

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Recent Developments in Natural and Synthetic Drug Research for Alzheimers Disease

Orhan, G., Orhan, İ. E., & Şener, B. (2006) · Letters in Drug Design & Discovery · doi:10.2174/157018006776743215 · Cited by 86 · see citing works

Asiaticoside: Attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax

Xu, C.-L., Wang, Q.-Z., Sun, L.-M., Li, X.-M., Deng, J.-M., Li, L.-F., Zhang, J., Xu, R., & Ma, S.-P. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.09.014 · Cited by 85 · see citing works

Protective effect of Centella asiatica extract and powder on oxidative stress in rats

Hussin, M., Hamid, A. A., Mohamad, S., Saari, N., Ismail, M., & Bejo, M. H. (2005) · Food Chemistry · doi:10.1016/j.foodchem.2005.10.022 · Cited by 82 · see citing works

Titrated Extract of Centella Asiatica (TECA) in the Treatment of Venous Insufficiency of the Lower Limbs

Pointel, J. P., Boccalon, H., Cloarec, M., Ledevehat, C., & Joubert, M. (1987) · Angiology · doi:10.1177/000331978703800106 · Cited by 71 · see citing works

Two new flavonoids from Centella asiatica (Linn.)

Subban, R., Veerakumar, A., Manimaran, R., Hashim, K. M., & Balachandran, I. (2008) · Journal of Natural Medicines · doi:10.1007/s11418-008-0229-0 · Cited by 70 · see citing works

Structure and potential immunological activity of a pectin from Centellaasiatica (L.) Urban

Wang, X., Dong, Q., Zuo, J., & Fang, J. (2003) · Carbohydrate Research · doi:10.1016/s0008-6215(03)00380-x · Cited by 69 · see citing works

Effect of Centella asiatica leaf powder on oxidative markers in brain regions of prepubertal mice in vivo and its in vitro efficacy to ameliorate 3-NPA-induced oxidative stress in mitochondria

Shinomol, G. K., & ., M. (2008) · Phytomedicine · doi:10.1016/j.phymed.2008.04.010 · Cited by 69 · see citing works

Inhibitory effects of Centella asiatica on azoxymethane-induced aberrant crypt focus formation and carcinogenesis in the intestines of F344 rats

Bunpo, P., Kataoka, K., Arimochi, H., Nakayama, H., Kuwahara, T., Bando, Y., Izumi, K., Vinitketkumnuen, U., & Ohnishi, Y. (2004) · Food and Chemical Toxicology · doi:10.1016/j.fct.2004.06.022 · Cited by 67 · see citing works

Spectroscopic determination of structures of triterpenoid trisaccharides from Centella asiatica

Sahu, N. P., ROY, S. K., & Mahato, S. B. (1989) · Phytochemistry · doi:10.1016/s0031-9422(00)98106-8 · Cited by 66 · see citing works

Gotu Kola (Centella Asiatica) extract enhances phosphorylation of cyclic AMP response element binding protein in neuroblastoma cells expressing amyloid beta peptide

Xu, Y., Cao, Z., Khan, I., & Luo, Y. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-13311 · Cited by 62 · see citing works

Effect of the triterpenoid fraction of Centella asiatica on macromolecules of the connective matrix in human skin fibroblast cultures.

Tenni, R., Zanaboni, G., Agostini, M. P. D., Rossi, A., Bendotti, C., & Cetta, G. (1988) · PubMed · Cited by 61 · see citing works

Chemical constituents ofCentella asiatica

Siddiqui, B. S., Aslam, H., Ali, S. T., Khan, S., & Begum, S. (2007) · Journal of Asian Natural Products Research · doi:10.1080/10286020600782454 · Cited by 61 · see citing works

Mono- and sesquiterpenoids from Hydrocotyle and Centella species

Asakawa, Y., Matsuda, R., & TAKEMOTO, T. (1982) · Phytochemistry · doi:10.1016/0031-9422(82)85264-3 · Cited by 58 · see citing works

Beneficial effects of Centella asiatica aqueous extract against arsenic‐induced oxidative stress and essential metal status in rats

Flora, S. J. S., & Gupta, R. (2007) · Phytotherapy Research · doi:10.1002/ptr.2208 · Cited by 57 · see citing works

Anti-allergic, anti-pruritic, and anti-inflammatory activities of Centella asiatica extracts

George, M., & Joseph, L. (2010) · African Journal of Traditional Complementary and Alternative Medicines · doi:10.4314/ajtcam.v6i4.57206 · Cited by 54 · see citing works

Enhancement of Hippocampal CA3 Neuronal Dendritic Arborization by Centella asiatica (Linn) Fresh Leaf Extract Treatment in Adult Rats

Gadahad, M. R. K., Rao, M. S. R., & Rao, G. S. (2008) · Journal of the Chinese Medical Association · doi:10.1016/s1726-4901(08)70066-2 · Cited by 51 · see citing works

Medicinal Foodstuffs. XXVI. Inhibitors of Aldose Reductase and New Triterpene and Its Oligoglycoside, Centellasapogenol A and Centellasaponin A, from Centella asiatica (Gotu Kola)

Yoshikawa, M., Matsuda, H., Morikawa, T., & Ueda, H. R. (2001) · Heterocycles · doi:10.3987/com-01-9259 · Cited by 51 · see citing works

Studies on Indian Medical History

Meulenbeld, G. J., & Wujastyk, D. (1987) · BRILL eBooks · doi:10.1163/9789004646582 · Cited by 49 · see citing works

EFFECT OF CENTELLA ASIATICA ON MILD COGNITIVE IMPAIRMENT (MCI) AND OTHER COMMON AGE-RELATED CLINICAL PROBLEMS

Tiwari, S., Singh, S., Patwardhan, K., Gehlot, S., & Gambhir, I. S. (2008) · Cited by 49 · see citing works

[Effects of total triterpenes of Centella asiatica on the corticosterone levels in serum and contents of monoamine in depression rat brain].

Chen, Y., Han, T., Rui, Y., Yin, M., Qin, L., & Zheng, H. (2005) · PubMed · Cited by 49 · see citing works

Centella asiatica water extract inhibits iPLA2 and cPLA2 activities in rat cerebellum

Barbosa, N. R., Pittella, F., & Gattaz, W. F. (2008) · Phytomedicine · doi:10.1016/j.phymed.2008.02.007 · Cited by 46 · see citing works

Enhancement of Amygdaloid Neuronal Dendritic Arborization by Fresh Leaf Juice of Centella asiatica (Linn) during Growth Spurt Period in Rats

Mohandas Rao, K. G., Rao, M. S. R., & Rao, S. (2007) · Evidence-based Complementary and Alternative Medicine · doi:10.1093/ecam/nem079 · Cited by 45 · see citing works

A Bioactive Polyacetylene Compound Isolated from Centella asiatica

Govindan, G. N., Sambandan, T. G., Govindan, M., Sinskey, A. J., Vanessendelft, J., Ilham, A. M., & Rha, C. (2007) · Planta Medica · doi:10.1055/s-2007-981521 · Cited by 41 · see citing works

Flavor Characterization of Sugar‐Added Pennywort ( Centella asiatica L.) Juices Treated with Ultra‐High Pressure and Thermal Processes

Apichartsrangkoon, A., Wongfhun, P., & Gordon, M. H. (2009) · Journal of Food Science · doi:10.1111/j.1750-3841.2009.01358.x · Cited by 37 · see citing works

The antiepileptic effect of Centella asiatica on the activities of Na + /K + , Mg 2+ and Ca 2+ -ATPases in rat brain during pentylenetetrazol-induced epilepsy

Rajendra, W., Visweswari, G., Prasad, K. S. S., & Lokanatha, V. (2010) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.64504 · Cited by 36 · see citing works

Flavour characterisation of fresh and processed pennywort (Centella asiatica L.) juices

Wongfhun, P., Gordon, M. H., & Apichartsrangkoon, A. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.05.072 · Cited by 35 · see citing works

Precision improvement for the analysis of flavonoids in selected Thai plants by capillary zone electrophoresis

Suntornsuk, L., & Anurukvorakun, O. (2005) · Electrophoresis · doi:10.1002/elps.200410203 · Cited by 33 · see citing works

Two New Triterpene Glycosides fromCentella asiatica

Rumalla, C. S., Ali, Z., Weerasooriya, A. D., Smillie, T. J., & Khan, I. A. (2010) · Planta Medica · doi:10.1055/s-0029-1240864 · Cited by 31 · see citing works

Chemical examination of Centella asiatica linn—III

Singh, B., & Rastogi, R. P. (1968) · Phytochemistry · doi:10.1016/s0031-9422(00)85642-3 · Cited by 30 · see citing works

Microcirculatory Effects of Total Triterpenic Fraction of Centella asiatica in Chronic Venous Hypertension: Measurement by Laser Doppler, TcPo 2 -co 2 , and Leg Volumetry

Cesarone, M. R., Belcaro, G. V., RULO, A. H. F., GRIFFIN, M. B., Ricci, A., IPPOLITO, E., Sanctis, M. T. D., INCANDELA, L., Bavera, P. M., Cacchio, M., et al. (2001) · Angiology · doi:10.1177/000331970105202s09 · Cited by 29 · see citing works

Separation and Determination of Madecassic Acid in Extracts of Centella asiatica Using High Performance Liquid Chromatography with β-Cyclodextrin as Mobile Phase Additive

PAN, J., Kai, G., YUAN, C., ZHOU, B., Jin, R., & YUAN, Y. (2007) · Chinese Journal of Chromatography · doi:10.1016/s1872-2059(07)60009-1 · Cited by 28 · see citing works

Inhibition of H2O2-induced DNA damage in single cell gel electrophoresis assay (comet assay) by castasterone isolated from leaves of centella asiatica

Sondhi, N., Bhardwaj, R., Kaur, S., Chandel, M., Kumar, N., & Singh, B. (2010) · Health · doi:10.4236/health.2010.26088 · Cited by 27 · see citing works

The Effect Of Centella Asiatica On The General Mental Ability Of Mentally Retarded Children

Rao, V. R. A., Srinivasan, K., & Rao, T. K. G. (1977) · Indian Journal of Psychiatry · Cited by 27 · see citing works

Characterization Of An Ursane Triterpenoid From Centella Asiatica With Growth Inhibitory Activity Against Spilarctia Obliqua

Shukla, Y. N., Srivastava, R., Tripathi, A. K., & Prajapati, V. (2000) · Pharmaceutical Biology · doi:10.1076/1388-0209(200009)3841-aft262 · Cited by 25 · see citing works

Anti-Convulsant Activity of Different Extracts of Centella asiatica and Bacopa monnieri in Animals

Sudha Revathy, S., Kumaresan, S., Agrawal, A., David, J., & Venkataraman, B. V. (2002) · Journal of Natural Remedies · doi:10.18311/jnr/2002/342 · Cited by 24 · see citing works

Crude extract of Centella asiatica and products derived from its glycosides as oral antifertility agents.

Dutta, T., & Basu, U. (1968) · PubMed · Cited by 22 · see citing works

EVALUATION OF EFFECT OF CENTELLA ASIATICA ON CCL4 INDUCED RAT LIVER DAMAGE

Pingale, S. S., & Mandal, G. (2008) · Cited by 21 · see citing works

Isobolographically additive anticonvulsant activity between Centella asiatica's ethyl acetate fraction and some antiepileptic drugs.

Vattanajun, A., Watanabe, H., Tantisira, M. H., & Tantisira, B. (2005) · PubMed · Cited by 20 · see citing works

Neuropharmacology of an Extract Derived fromCentella asiatica

Ganachari, M. S., Babu, V. D., & Katare, S. (2004) · Pharmaceutical Biology · doi:10.1080/13880200490514177 · Cited by 20 · see citing works

The treatment of leprosy

Waters, M. F. (1983) · Tubercle · doi:10.1016/0041-3879(83)90018-1 · Cited by 20 · see citing works

Pharmacological and toxicological studies on Centella asiatica extract

DeLucia, R., Sertié, J. A. A., Camargo, E. A., & Panizza, S. (1997) · Fitoterapia · Cited by 19 · see citing works

Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract

Bilbao, I., Aguirre, A., Zabala, R., González, R., Ratón, J. A., & Pérez, J. L. D. (1995) · Contact Dermatitis · doi:10.1111/j.1600-0536.1995.tb02087.x · Cited by 17 · see citing works

Allergic contact dermatitis due to Centella asiatica: a new case.

Gonzalo-Garijo, Á., Arranz, F. R., & González, P. B. (1996) · PubMed · Cited by 15 · see citing works

Contact dermatitis due to Centella asiatica

Gomes, J., Pereira, T. M., Vilarinho, C., Duarte, M. D. L., & Brito, C. (2010) · Contact Dermatitis · doi:10.1111/j.1600-0536.2009.01651.x · Cited by 15 · see citing works

Role ofCentella asiaticaon cerebral post-ischemic reperfusion and long-term hypoperfusion in rats

Raghavendra, M., Maiti, R., Kumar, S., Trigunayat, A., Mitra, S., & Acharya, S. (2009) · International Journal of Green Pharmacy · doi:10.4103/0973-8258.54893 · Cited by 14 · see citing works

Five New Triterpene Glycosides from Centella asiatica

Kuroda, M., Mimaki, Y., Harada, H., Sakagami, H., & Sashida, Y. (2001) · Medical Entomology and Zoology · Cited by 13 · see citing works

Use of a common Indian herb "Mandukaparni" in the treatment of leprosy (preliminary report).

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Biochemical analysis of granulation tissue in steroid and Centella asiatica (Linn) treated rats

Shetty, B. S., Udupa, S. L., & Udupa, A. L. (2008) · Pharmacologyonline · Cited by 10 · see citing works

Structures of New Ursane- and Oleanane-Type Triterpene Oligoglycosides, Centellasaponins B, C, and D, from Centella asiatica Cultivated in Sri Lanka

Matsuda, H., Morikawa, T., Ueda, H. R., & Yoshikawa, M. (2001) · Cited by 9 · see citing works

Evaluation of five indigenous medicinal plants of Sindh, Pakistan for their antifungal potential.

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ChemInform Abstract: Medicinal Foodstuffs. Part 26. Inhibitors of Aldose Reductase and New Triterpene and Its Oligoglycoside, Centellasapogenol A and Centellasaponin A, from Centella asiatica (Gotu Kola).

Matsuda, H., Morikawa, T., Ueda, H. R., & Yoshikawa, M. (2001) · ChemInform · doi:10.1002/chin.200148147 · Cited by 7 · see citing works

Studies to understand the effect of Centella asiatica on Aβ(42) aggregation in vitro

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Structural Features of a Polysaccharide from Centella asiatica

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Centella asiatica (L.) Urb.

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Neuroprotective Herbs for the Management of Alzheimer’s Disease

Gregory, J., Vengalasetti, Y. V., Bredesen, D. E., & Rao, R. V. (2021) · Biomolecules · doi:10.3390/biom11040543 · Cited by 238 · see citing works

Chronic Stress and Oxidative Stress as Common Factors of the Pathogenesis of Depression and Alzheimer’s Disease: The Role of Antioxidants in Prevention and Treatment

Juszczyk, G., Mikulska, J., Kasperek, K., Pietrzak, D., Mrozek, W., & Herbet, M. (2021) · Antioxidants · doi:10.3390/antiox10091439 · Cited by 235 · see citing works

Green Synthesis of Metallic Nanoparticles Using Some Selected Medicinal Plants from Southern Africa and Their Biological Applications

Aboyewa, J. A., Sibuyi, N. R. S., Meyer, M., & Oguntibeju, O. O. (2021) · Plants · doi:10.3390/plants10091929 · Cited by 191 · see citing works

Prodrugs of triterpenoids and their derivatives

Zhou, M., Zhang, R., Wang, M., Xu, G., & Liao, S. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.03.005 · Cited by 119 · see citing works

Indian Medicinal Herbs and Formulations for Alzheimer’s Disease, from Traditional Knowledge to Scientific Assessment

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Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency

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In vitro and In vivo Antioxidant, Anti-hyperlipidemic Properties and Chemical Characterization of Centella asiatica (L.) Extract

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Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism

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Chitosan-based microneedle arrays for dermal delivery of Centella asiatica

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Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo

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Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy

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Asiatic acid protects differentiated PC12 cells from Aβ25–35-induced apoptosis and tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β signaling

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Plants and phytochemicals for treatment of peptic ulcer: An overview

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Protective Effect of Centella asiatica against Aluminium-Induced Neurotoxicity in Cerebral Cortex, Striatum, Hypothalamus and Hippocampus of Rat Brain- Histopathological, and Biochemical Approach

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Blood-Brain Barrier Permeability of Asiaticoside, Madecassoside and Asiatic Acid in Porcine Brain Endothelial Cell Model

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Antioxidative role of Traditional Chinese Medicine in Parkinson's disease

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Decreasing α-synuclein aggregation by methanolic extract of Centella asiatica in zebrafish Parkinson's model

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Role of Flavonoids as Wound Healing Agent

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Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review

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Protection of mouse brain from paracetamol-induced stress by Centella asiatica methanol extract.

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Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

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Effects of SuperUlam on Supporting Concentration and Mood: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

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Differentiation of Three Centella Species in Australia as Inferred from Morphological Characteristics, ISSR Molecular Fingerprinting and Phytochemical Composition

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Hippocampal amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid GluA1 ( AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment withCentella asiaticaextract in adolescent rats

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Strategies for Improving Healing of the Gastric Epithelium Using Oral Solid Dispersions Loaded with Pentacyclic Triterpene–Rich Centella Extract

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Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?—A Review

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Role of indigenous herbs in the management of Alzheimer′s disease

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Medhya Rasayanas in Brain Function and Disease

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The protective effect of Centella asiatica and its constituent, araliadiol on neuronal cell damage and cognitive impairment

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Phytochemical and pharmacological evaluation of organic and non-organic cultivated nutritional Centella asiatica collected after different time intervals of harvesting

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Neurotransmitter, Antioxidant and Anti-neuroinflammatory Mechanistic Potentials of Herbal Medicines in Ameliorating Autism Spectrum Disorder

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Morphological Description and Ethnobotanical Review of the Orphan Crop Myin-Hkwa (Centella asiatica L.) From Myanmar

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Biomass and centellosides production in two elite Centella asiatica germplasms from India in response to seasonal variation

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Protective effects of asiatic acid in a spontaneous type 2 diabetic mouse model

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An Investigation of the Differential Effects of Ursane Triterpenoids fromCentella asiatica, and Their Semisynthetic Analogues, on GABAA Receptors

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Behavioral and neurochemical consequences of perinatal exposure to lead in adult male Wistar rats: protective effect by Centella asiatica

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Medicinal herbal remedies in neurodegenerative diseases: an update on antioxidant potential

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Asiatic acid, an active substance of Centella asiatica, presynaptically depresses glutamate release in the rat hippocampus

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Growth Increase in the Herbaceous Plant Centella asiatica by the Plant Growth-Promoting Rhizobacteria Priestia megaterium HyangYak-01

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Study of ameliorating effects of ethanolic extract of Centella asiatica on learning and memory deficit in animal models.

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Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)

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A Comparative Study of the Hepatoprotective Effect of Centella asiatica Extract (CA-HE50) on Lipopolysaccharide/d-galactosamine-Induced Acute Liver Injury in C57BL/6 Mice

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Evaluation of antimicrobial, anticancer potential and Flippase induced leakage in model membrane of Centella asiatica fabricated MgONPs

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Diabetes mellitus and Alzheimer's disease: Understanding disease mechanisms, their correlation, and promising dual activity of selected herbs

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Antioxidant Activities of Methanol Extracts from Selected Taiwanese Herbaceous Plants

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Ameliorative Role of Nutraceuticals on Neurodegenerative Diseases Using theDrosophila melanogasteras a Discovery Model to Define Bioefficacy

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Ethno-medicinal plants used for herbal medication of jaundice by the indigenous community of Tripura, India

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Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches

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Characterisation of indigenous plants for herbal formulations preparation based on pharmacognostic and physiochemical data

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Centella asiatica and Its Fractions Reduces Lipid Peroxidation Induced by Quinolinic Acid and Sodium Nitroprusside in Rat Brain Regions

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Rice-Based Alcoholic Fermented Beverages of North-East India: Insight into Ethnic Preparation, Microbial Intervention, Ethnobotany, and Health Benefits

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Neuroprotective prospectives of triterpenoids

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Consumption of fresh Centella asiatica improves short term alertness and contentedness in healthy females

Lawal, O. M., Wakel, F., & Dekker, M. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104337 · Cited by 15 · see citing works

The recovery and protective effects of asiatic acid on differentiated human neuroblastoma SH-SY5Y cells cytotoxic-induced by cholesterol

Ternchoocheep, K., Surangkul, D., & Ysothonsreekul, S. (2017) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/j.apjtb.2017.01.012 · Cited by 15 · see citing works

Synthesis of madecassic acid derivatives and their cytotoxic activity

Lộc, T. V., Như, V. T. Q., Chiến, T. V., Hà, L. T. T., Thảo, T. T. P., & Sung, T. V. (2018) · Zeitschrift für Naturforschung B · doi:10.1515/znb-2017-0172 · Cited by 14 · see citing works

LC-ESI/MS and GC-MS Methanol Extract Analysis, Phytochemical and Antimicrobial Activity Studies of Centella asiatica

Ondeko, D. A., Juma, B. F., Baraza, L. D., & Nyongesa, P. K. (2020) · Asian Journal of Chemical Sciences · doi:10.9734/ajocs/2020/v8i319046 · Cited by 14 · see citing works

Investigation of the in vitro antibacterial, cytotoxic and in vivo analgesic effects of silver nanoparticles coated with Centella asiatica plant extract

Bozkaya, O., Ekici, H., Gök, Z. G., Bozkaya, E., Ekici, S., Yiğitoğlu, M., & Vargel, İ. (2022) · Ankara Üniversitesi Veteriner Fakültesi Dergisi · doi:10.33988/auvfd.1014802 · Cited by 14 · see citing works

Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology

Ding, B., Niu, W., Wang, S., Zhang, F., Wang, H., Chen, X., Chen, S., Ma, S., Kang, W., Wang, M., et al. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115106 · Cited by 14 · see citing works

The protective effect of asiatic acid on podocytes in the kidney of diabetic rats.

Chen, Y.-N., Wu, C., Shi, B., Qian, K., & Ding, Y. (2018) · Europe PMC (PubMed Central) · Cited by 14 · see citing works

Exploring aryl hydrocarbon receptor (AhR) as a target for Bisphenol-A (BPA)-induced pancreatic islet toxicity and impaired glucose homeostasis: Protective efficacy of ethanol extract of Centella asiatica

Banerjee, O., Singh, S., Prasad, S. K., Bhattacharjee, A., Seal, T., Mandal, J., Sinha, S., Banerjee, A., Maji, B. K., & Mukherjee, S. (2023) · Toxicology · doi:10.1016/j.tox.2023.153693 · Cited by 13 · see citing works

Centella asiatica Extract Attenuates Kidney Fibrosis Through Reducing Mesenchymal Transition and Inflammation in Ureteral Ligation Model in Mice

Sari, D. C. R., Budiharjo, S., Afifah, H., Jasmin, D., Kokasih, O., Putri, T., Arifiani, K., Setyaningsih, W. A. W., & Arfian, N. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.621894 · Cited by 15 · see citing works

Exploiting Medicinal Plants as Possible Treatments for Acne Vulgaris

Lambrechts, I. A., Canha, M. N. D., & Lall, N. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812475-8.00004-4 · Cited by 13 · see citing works

Screening of different extraction methods for maximum production of total flavonoids, tannins, and antioxidants from Centella asiatica

Hossain, M. A., Ahmad, N., Alam, M., Hossain, M. M., & Sarkar, A. (2024) · Food Research · doi:10.26656/fr.2017.8(1).057 · Cited by 12 · see citing works

Synthesis of asiatic acid derivatives and their cytotoxic activity

Van, L. T., Thi, Q. N. V., Van, C. T., Thi, P. T. T., Thi, N. P., Tuan, T. N., Thi, T. H. L., Thị, N. N., Thi, T. D., & Van, S. T. (2018) · Medicinal Chemistry Research · doi:10.1007/s00044-018-2176-y · Cited by 12 · see citing works

A review of antioxidant and anti-acetylcholinesterase activities of Centella asiatica (L.) Urb. for the treatment of Alzheimer’s disease

Abbas, S., Latif, M. S., Shafie, N. S., Ghazali, M. I., Abidin, N. A. Z., Mustafa, M. K., & Kormin, F. B. (2021) · Food Research · doi:10.26656/fr.2017.5(2).355 · Cited by 12 · see citing works

Analysis of antibacterial, anti-inflammatory, and skin-whitening effect of Centella asiatica (L.) Urban

Goo, Y., Kil, Y. S., Sin, S. M., Lee, D. Y., Jeong, W. M., Ko, K., Yang, K. J., Kim, Y., & Lee, S.-W. (2018) · Journal of Plant Biotechnology · doi:10.5010/jpb.2018.45.2.117 · Cited by 12 · see citing works

doi:10.1155/2012/946259 Review Article Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential

Orhan, I. E. (2016)

Potential neurological applications of Centella asiatica: a brief review

Gofir, A., Wibowo, S., & Hakimi, M. (2021) · Indonesian Journal of Pharmacology and Therapy · doi:10.22146/ijpther.1693 · Cited by 6 · see citing works

Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy ageing

Sabaragamuwa, R., Perera, C. O., & Fedrizzi, B. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.07.024 · Cited by 103 · see citing works

Gotu Kola (Centella asiatica)

Belwal, T., Andola, H. C., Atanassova, M., Joshi, B., Suyal, R., Thakur, S., Bisht, A., Jantwal, A., BHATT, I. D., & Rawal, R. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812491-8.00038-2 · Cited by 40 · see citing works

Recent Updates in Neuroprotective and Neuroregenerative Potential of Centella asiatica.

Lokanathan, Y., Omar, N., Puzi, N. N. A., Saim, A. B., & Idrus, R. B. H. (2016) · Europe PMC (PubMed Central) · Cited by 82 · see citing works