FGF-21 as a novel metabolic regulator

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Items 101–200 of 1,008

  1. FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting
    Liang, Qingning, Zhong, Ling, Zhang, Jialiang, Wang, Yu, Bornstein, Stefan R., Triggle, Chris R., Ding, Hong, Lam, Karen S.L., Xu, Aimin · 2014 · Diabetes
  2. Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity
    Berglund, Eric D., Li, Candice Y., Bina, Holly A., Lynes, Sara E., Michael, M. Dodson, Shanafelt, Armen B., Kharitonenkov, Alexei, Wasserman, David H. · 2009 · Endocrinology
  3. Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models
    Nan Yao Su, Min Young Jin, Lin Chen · 2014 · Bone Research
  4. Skeletal muscle mitochondrial remodeling in exercise and diseases
    Zhenji Gan, Tingting Fu, Daniel P. Kelly, Rick B. Vega · 2018 · Cell Research
  5. Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans
    Kim, Kook Hwan, Kim, Seong Hun, Min, Young-Ki, Yang, Hun-Mo, Lee, Jeong-Beom, Lee, Myung-Shik · 2013 · PLoS ONE
  6. Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats
    David A. Sarruf, Joshua P. Thaler, Gregory J. Morton, Jonathan P. German, Jonathan D. Fischer, Kayoko Ogimoto, Michael W. Schwartz · 2010 · Diabetes
  7. Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21
    Owen, Bryn M., Mangelsdorf, David J., Kliewer, Steven A. · 2015 · Trends in Endocrinology & Metabolism
  8. The lighter side of BDNF
    Noble, Emily E., Billington, Charles J., Kotz, Catherine M., Wang, ChuanFeng · 2011 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  9. Liver-specific Activities of FGF19 Require Klotho beta
    Benjamin C. Lin, Manping Wang, C. A. Blackmore, Luc Desnoyers · 2007 · Journal of Biological Chemistry
  10. Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism
    Amaia Rodríguez, Silvia Ezquerro, Leire Méndez-Giménez, Sara Becerril, Gema Frühbeck · 2015 · American Journal of Physiology-Endocrinology and Metabolism
  11. The fasting polypeptide FGF21 can enter brain from blood
    Hsuchou, Hung, Pan, Weihong, Kastin, Abba J. · 2007 · Peptides
  12. Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity
    Mraz, M., Bartlova, M., Lacinova, Z., Michalsky, D., Kasalicky, M., Haluzikova, D., Matoulek, M., Dostalova, I., Humenanska, V., Haluzik, M. · 2009 · Clinical Endocrinology
  13. Cytokines and abnormal glucose and lipid metabolism
    Shi, Jie, Fan, Jiangao, Su, Qing, Yang, Zhen · 2019 · Frontiers in Endocrinology
  14. Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21
    Yu Li, Kimberly Wong, Amber Jin Giles, Jianwei Jiang, Jong Woo Lee, Andrew Charles Adams, Alexei Kharitonenkov, Qin Yang, Bin Gao, Leonard Guarente et al. · 2013 · Gastroenterology
  15. A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21
    Steven A. Kliewer, David J. Mangelsdorf · 2019 · Cell Metabolism
  16. Adiposity and Insulin Resistance in Humans: The Role of the Different Tissue and Cellular Lipid Depots
    SAMANTHA L. HOCKING, Dorit Samocha‐Bonet, Kerry–Lee Milner, Jerry Richard Greenfield, Donald J. Chisholm · 2013 · Endocrine Reviews
  17. The Ever-Expanding Myokinome: Discovery Challenges and Therapeutic Implications
    Whitham, Martin, Febbraio, Mark A. · 2016 · Nature Reviews Drug Discovery
  18. Fibroblast Growth Factor 21—Metabolic Role in Mice and Men
    Staiger, Harald, Keuper, Michaela, Berti, Lucia, Hrabě de Angelis, Martin, Häring, Hans-Ulrich · 2017 · Endocrine Reviews
  19. Fibroblast growth factor 21 drives dynamics of local and systemic stress responses in mitochondrial myopathy with mtDNA deletions
    Forsström, Saara, Jackson, Christopher B., Carroll, Christopher J., Kuronen, Mervi, Pirinen, Eija, Pradhan, Swagat, Marmyleva, Anastasiia, Auranen, Mari, Kleine, Iida-Marja, Khan, Nahid A. et al. · 2019 · Cell Metabolism
  20. Myokines: The endocrine coupling of skeletal muscle and bone
    Marta Gomarasca, Giuseppe Banfi, Giovanni Lombardi · 2019 · Advances in clinical chemistry
  21. Fibroblast Growth Factor 21 Prevents Atherosclerosis by Suppression of Hepatic Sterol Regulatory Element-Binding Protein-2 and Induction of Adiponectin in Mice
    Zhuofeng Lin, Xuebo Pan, Fan Wu, Dewei Ye, Yi Zhang, Yu Wang, Leigang Jin, Qizhou Lian, Yü Huang, Hong Ding et al. · 2015 · Circulation
  22. The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue
    Adams, Andrew C., Yang, Chaofeng, Coskun, Tamer, Cheng, Christine C., Gimeno, Ruth E., Luo, Yongde, Kharitonenkov, Alexei · 2013 · Molecular Metabolism
  23. Fibroblast growth factor 21 protects the heart from oxidative stress
    Anna Planavila, Ibon Redondo‐Angulo, Francesc Ribas‐Aulinas, Glòria Garrabou, Jordi Casademont, Marta Giralt, Francesc Villarroya · 2014 · Cardiovascular Research
  24. Calcium and phosphate homeostasis: Concerted interplay of new regulators
    Renkema, Kirsten Y., Alexander, R. Todd, Bindels, René J., Hoenderop, Joost G. · 2008 · Annals of Medicine
  25. Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis
    Aimin Wu, Bin Feng, Jie Yu, Lijun Yan, Lianqiang Che, Yong Zhuo, Yuheng Luo, Bing Yu, De Wu, Daiwen Chen · 2021 · Redox Biology
  26. FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia
    Lan, Tian, Morgan, Donald A., Rahmouni, Kamal, Sonoda, Junichiro, Fu, Xiaorong, Burgess, Shawn C., Holland, William L., Kliewer, Steven A., Mangelsdorf, David J. · 2017 · Cell Metabolism
  27. Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets
    Fisher, Ffolliott M., Chui, Patricia C., Nasser, Imad A., Popov, Yury, Cunniff, Jeremy C., Lundasen, Thomas, Kharitonenkov, Alexei, Schuppan, Detlef, Flier, Jeffrey S., Maratos-Flier, Eleftheria · 2014 · Gastroenterology
  28. FGF21–Sirtuin 3 Axis Confers the Protective Effects of Exercise Against Diabetic Cardiomyopathy by Governing Mitochondrial Integrity
    Leigang Jin, Leiluo Geng, Lei Ying, Lingling Shu, Kevin Ye, Ranyao Yang, Yan Liu, Yao Wang, Yin Cai, Xue Xiang Jiang et al. · 2022 · Circulation
  29. Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer
    Jae Myoung Suh, Johan W. Jonker, Maryam Ahmadian, Regina M. Goetz, Denise E. Lackey, Olivia Osborn, Zhifeng Huang, Weilin Liu, Eiji Yoshihara, Theo H. van Dijk et al. · 2014 · Nature
  30. Pegbelfermin (BMS‐986036), PEGylated FGF21, in Patients with Obesity and Type 2 Diabetes: Results from a Randomized Phase 2 Study
    Charles, Edgar D., Neuschwander‐Tetri, Brent A., Pablo Frias, Juan, Kundu, Sudeep, Luo, Yi, Tirucherai, Giridhar S., Christian, Rose · 2019 · Obesity
  31. Hepatokines and metabolism: Deciphering communication from the liver
    Jensen-Cody, Sharon O., Potthoff, Matthew J. · 2021 · Molecular Metabolism
  32. Fetuin B is a secreted hepatocyte factor linking steatosis to impaired glucose metabolism
    Meex, Ruth C., Hoy, Andrew J., Morris, Alexander, Brown, Russell D., Lo, Jennifer C.Y., Burke, Melissa, Goode, Robert J.A., Kingwell, Bronwyn A., Kraakman, Michael J., Febbraio, Mark A. et al. · 2015 · Cell Metabolism
  33. Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism
    Makoto Kuro‐o · 2013 · Nature Reviews Nephrology
  34. Brown Adipose Tissue Responds to Cold and Adrenergic Stimulation by Induction of FGF21
    Chartoumpekis, Dionysius V, Habeos, Ioannis G, Ziros, Panos G, Psyrogiannis, Agathoklis I, Kyriazopoulou, Venetsana E, Papavassiliou, Athanasios G · 2011 · Molecular Medicine
  35. FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues
    Schlein, Christian, Talukdar, Saswata, Heine, Markus, Fischer, Alexander W., Krott, Lucia M., Nilsson, Stefan K., Brenner, Martin B., Heeren, Joerg, Scheja, Ludger · 2016 · Cell Metabolism
  36. The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis
    Mark A. Herman, Varman T. Samuel · 2016 · Trends in Endocrinology and Metabolism
  37. Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism
    Makoto Kuro‐o · 2006 · Current Opinion in Nephrology & Hypertension
  38. Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation
    Yakun Ren, Hao Zhao, Chunyan Yin, Xi Lan, Litao Wu, Xiaojuan Du, Helen R. Griffiths, Dan Gao · 2022 · Frontiers in Endocrinology
  39. Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions
    Habegger, Kirk M., Stemmer, Kerstin, Cheng, Christine, Müller, Timo D., Heppner, Kristy M., Ottaway, Nickki, Holland, Jenna, Hembree, Jazzminn L., Smiley, David, Gelfanov, Vasily et al. · 2013 · Diabetes
  40. Interplay between FGF21 and insulin action in the liver regulates metabolism
    Brice Emanuelli, Sara G. Vienberg, Graham Smyth, Christine Cheng, Kristin I. Stanford, Manimozhiyan Arumugam, Mervyn D. Michael, Andrew Charles Adams, Alexei Kharitonenkov, C. Ronald Kahn · 2014 · Journal of Clinical Investigation
  41. Methionine-Restricted C57BL/6J Mice Are Resistant to Diet-Induced Obesity and Insulin Resistance but Have Low Bone Density
    Gene P. Ables, Carmen E. Perrone, David S. Orentreich, Norman Orentreich∥ · 2012 · PLoS ONE
  42. Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease
    Nobuyuki Itoh · 2010 · Cell and Tissue Research
  43. Fibroblast growth factor (FGF) signaling in development and skeletal diseases
    Teven, Chad M., Farina, Evan M., Rivas, Jane, Reid, Russell R. · 2014 · Genes & Diseases
  44. Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial
    Shihui Chen, Xiaolan Zhao, Jing Wan, Li Ran, Yu Qin, Xiaofang Wang, Yanxiang Gao, Furong Shu, Yong Zhang, Peng Liu et al. · 2015 · Pharmacological Research
  45. FGF21 attenuates lipolysis in human adipocytes – A possible link to improved insulin sensitivity
    Arner, Peter, Pettersson, Amanda, Mitchell, Pamela J., Dunbar, James D., Kharitonenkov, Alexei, Rydén, Mikael · 2008 · FEBS Letters
  46. FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism
    Hill, Cristal M., Laeger, Thomas, Dehner, Madeleine, Albarado, Diana C., Clarke, Blaise, Wanders, Desiree, Burke, Susan J., Collier, J. Jason, Qualls-Creekmore, Emily, Solon-Biet, Samantha M. et al. · 2019 · Cell Reports
  47. Fructose ingestion acutely stimulates circulating FGF21 levels in humans
    Dushay, Jody R., Toschi, Elena, Mitten, Emilie K., Fisher, Ffolliott M., Herman, Mark A., Maratos-Flier, Eleftheria · 2015 · Molecular Metabolism
  48. Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo
    ffolliott Martin Fisher, Jennifer L. Estall, Andrew Charles Adams, Patrick J. Antonellis, Holly A. Bina, Jeffrey S. Flier, Alexei Kharitonenkov, Bruce M. Spiegelman, Eleftheria Maratos–Flier · 2011 · Endocrinology
  49. Effect of endurance training on skeletal muscle myokine expression in obese men: Identification of apelin as a novel myokine
    Besse-Patin, A, Montastier, E, Vinel, C, Castan-Laurell, I, Louche, K, Dray, C, Daviaud, D, Mir, L, Marques, M-A, Thalamas, C et al. · 2014 · International Journal of Obesity
  50. FGF21 contributes to neuroendocrine control of female reproduction
    Owen, Bryn M, Bookout, Angie L, Ding, Xunshan, Lin, Vicky Y, Atkin, Stan D, Gautron, Laurent, Kliewer, Steven A, Mangelsdorf, David J · 2013 · Nature Medicine
  51. Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice
    João Paulo Camporez, François R. Jornayvaz, Max C. Petersen, Dominik Hans Pesta, Blas A. Guigni, Julie Serr, Dongyan Zhang, Mario Kahn, Varman T. Samuel, Michael J. Jurczak et al. · 2013 · Endocrinology
  52. Brown adipose tissue and thermogenesis
    Anna Fenzl, Florian Wolfgang Kiefer · 2014 · Hormone Molecular Biology and Clinical Investigation
  53. Genetic insights into the mechanisms of Fgf signaling
    J. Richard Brewer, Pierre Mazot, Philippe M. Soriano · 2016 · Genes & Development
  54. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake
    Tanaka, Toshiko, Ngwa, Julius S, van Rooij, Frank JA, Zillikens, M Carola, Wojczynski, Mary K, Frazier-Wood, Alexis C, Houston, Denise K, Kanoni, Stavroula, Lemaitre, Rozenn N, Luan, Jian’an et al. · 2013 · The American Journal of Clinical Nutrition
  55. An adipocentric perspective on the development and progression of non-alcoholic fatty liver disease
    Eunyoung Lee, Hannelie Korf, Antonio Vidal‐Puig · 2023 · Journal of Hepatology
  56. Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine
    Keipert, Susanne, Ost, Mario, Johann, Kornelia, Imber, Francine, Jastroch, Martin, van Schothorst, Evert M., Keijer, Jaap, Klaus, Susanne · 2014 · American Journal of Physiology-Endocrinology and Metabolism
  57. The Fgf Families in Humans, Mice, and Zebrafish: Their Evolutional Processes and Roles in Development, Metabolism, and Disease
    Nobuyuki Itoh · 2007 · Biological and Pharmaceutical Bulletin
  58. Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity
    Fredirick L. Mashili, Reginald L. Austin, Atul S. Deshmukh, Tomas Fritz, Kenneth Caidahl, Katrin Bergdahl, Juleen Rae Zierath, Alexander Chibalin, David E. Moller, Alexei Kharitonenkov et al. · 2011 · Diabetes/Metabolism Research and Reviews
  59. Myokines in insulin resistance and type 2 diabetes
    Kristin Eckardt, Sven Wolfgang Görgens, Silja Raschke, Jürgen Eckel · 2014 · Diabetologia
  60. Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases
    Sabrina Azevedo Machado, Gabriel Pasquarelli-do-Nascimento, Debora Santos da Silva, Gabriel Ribeiro Farias, Igor de Oliveira Santos, Luana Borges Baptista, Kelly Grace Magalhães · 2022 · Nutrition & Metabolism
  61. Fibroblast growth factor 21: from pharmacology to physiology
    Kliewer, Steven A, Mangelsdorf, David J · 2010 · The American Journal of Clinical Nutrition
  62. Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis
    BonDurant, Lucas D., Potthoff, Matthew J. · 2018 · Annual Review of Nutrition
  63. Mitochondrial metabolic manipulation by SARS-CoV-2 in peripheral blood mononuclear cells of patients with COVID-19
    Saima Ajaz, Mark J.W. McPhail, Keshav Kumar Singh, Salma F. Mujib, Francesca Maria Trovato, Salvatore Napoli, Kosh Agarwal · 2020 · American Journal of Physiology-Cell Physiology
  64. FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans
    Søberg, Susanna, Sandholt, Camilla H., Jespersen, Naja Z., Toft, Ulla, Madsen, Anja L., von Holstein-Rathlou, Stephanie, Grevengoed, Trisha J., Christensen, Karl B., Bredie, Wender L.P., Potthoff, Matthew J. et al. · 2017 · Cell Metabolism
  65. A very low carbohydrate ketogenic diet improves glucose tolerance inob/obmice independently of weight loss
    Michael K. Badman, Adam Richard Kennedy, Andrew Charles Adams, Pavlos Pissios, Eleftheria Maratos–Flier · 2009 · American Journal of Physiology-Endocrinology and Metabolism
  66. Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice
    Douris, Nicholas, Stevanovic, Darko M., Fisher, ffolliott M., Cisu, Theodore I., Chee, Melissa J., Nguyen, Ngoc L., Zarebidaki, Eleen, Adams, Andrew C., Kharitonenkov, Alexei, Flier, Jeffrey S. et al. · 2015 · Endocrinology
  67. FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases
    Erik J. Tillman, Tim Rolph · 2020 · Frontiers in Endocrinology
  68. FGF21 and the late adaptive response to starvation in humans
    Fazeli, Pouneh K., Lun, Mingyue, Kim, Soo M., Bredella, Miriam A., Wright, Spenser, Zhang, Yang, Lee, Hang, Catana, Ciprian, Klibanski, Anne, Patwari, Parth et al. · 2015 · Journal of Clinical Investigation
  69. A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain
    François R. Jornayvaz, Michael J. Jurczak, Hui‐Young Lee, Andreas L. Birkenfeld, David W. Frederick, Dongyang Zhang, Xian‐Man Zhang, Varman T. Samuel, Gerald I. Shulman · 2010 · American Journal of Physiology-Endocrinology and Metabolism
  70. Targeting nuclear receptors for the treatment of fatty liver disease
    Naoki Tanaka, Toshifumi Aoyama, Shioko Kimura, Frank J. Gonzalez · 2017 · Pharmacology & Therapeutics
  71. Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the βKlotho/FGFR1c Receptor Complex
    Foltz, Ian N., Hu, Sylvia, King, Chadwick, Wu, Xinle, Yang, Chaofeng, Wang, Wei, Weiszmann, Jennifer, Stevens, Jennitte, Chen, Jiyun Sunny, Nuanmanee, Noi et al. · 2012 · Science Translational Medicine
  72. Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients
    José Miguel Gallego-Escuredo, Javier Gómez‐Ambrosi, Victoria Catalán, Peré Domingo, Marta Giralt, Gema Frühbeck, Francesc Villarroya · 2014 · International Journal of Obesity
  73. Metabolic Inflammation—A Role for Hepatic Inflammatory Pathways as Drivers of Comorbidities in Nonalcoholic Fatty Liver Disease?
    Nadine Gehrke, Jörn Markus Schattenberg · 2020 · Gastroenterology
  74. Circulating fibroblast growth factors as metabolic regulators--a critical appraisal.
    B. Angelin, T. Larsson, M. Rudling · 2012 · Cell Metabolism
  75. The Impact of Diabetes and Diabetes Medications on Bone Health
    Matthew Philip Gilbert, Richard E. Pratley · 2015 · Endocrine Reviews
  76. Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice
    Naomi Kamimura, Kiyomi Nishimaki, Ikuroh Ohsawa, Shigeo Ohta · 2011 · Obesity
  77. Effects of postbariatric surgery weight loss on adipokines and metabolic parameters: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy—a prospective randomized trial
    Bettina Karin Wölnerhanssen, Ralph Peterli, Robert E. Steinert, Thomas T. A. Peters, Yves Borbély, Christoph Beglinger · 2011 · Surgery for Obesity and Related Diseases
  78. Functional thermogenic beige adipogenesis is inducible in human neck fat
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  79. Activation of Nrf2 signaling by natural products-can it alleviate diabetes?
    Manuel Matzinger, Katrin Fischhuber, Elke H. Heiß · 2017 · Biotechnology Advances
  80. Pharmacologic Effects of FGF21 Are Independent of the “Browning” of White Adipose Tissue
    Véniant, Murielle M., Sivits, Glenn, Helmering, Joan, Komorowski, Renee, Lee, Jae, Fan, Wei, Moyer, Carolyn, Lloyd, David J. · 2015 · Cell Metabolism
  81. Mechanisms of Increased In Vivo Insulin Sensitivity by Dietary Methionine Restriction in Mice
    Kirsten P. Stone, Desiree Wanders, Manda Orgeron, Cory C. Cortez, Thomas W. Gettys · 2014 · Diabetes
  82. Fibroblast Growth Factor-21 Is Induced in Human Skeletal Muscles by Hyperinsulinemia
    Hojman, Pernille, Pedersen, Maria, Nielsen, Anders Rinnov, Krogh-Madsen, Rikke, Yfanti, Christina, Åkerstrom, Thorbjørn, Nielsen, Søren, Pedersen, Bente Klarlund · 2009 · Diabetes
  83. The Klotho gene family as a regulator of endocrine fibroblast growth factors
    Hiroshi Kurosu, Makoto Kuro‐o · 2008 · Molecular and Cellular Endocrinology
  84. The PPARα-FGF21 Hormone Axis Contributes to Metabolic Regulation by the Hepatic JNK Signaling Pathway
    Santiago Vernia, Julie Cavanagh, Luisa García-Haro, Guadalupe Sabio, Tamera Barrett, Dae Young Jung, Jason K. Kim, Jia L. Xu, Hennady P. Shulha, Manuel G. Garber et al. · 2014 · Cell Metabolism
  85. Inventing new medicines: The FGF21 story
    Alexei Kharitonenkov, Andrew Charles Adams · 2014 · Molecular Metabolism
  86. Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet
    Giuseppina Mattace Raso, Raffaele Simeoli, Roberto Russo, Anna Iacono, Anna Natalizia Santoro, Orlando Paciello, Maria Carmela Ferrante, Roberto Berni Canani, Antonio Calignano, Rosaria Meli · 2013 · PLoS ONE
  87. Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease
    Yusuf Nadir Yilmaz, Fatih Eren, Oya Yönal, Ramazan Kurt, Bilge Aktaş, Çiğdem Çelikel, Osman Cavit Özdogan, Neşe İmeryüz, Cem Kalaycı, Erol Avşar · 2010 · European Journal of Clinical Investigation
  88. TNF-α Represses β-Klotho Expression and Impairs FGF21 Action in Adipose Cells: Involvement of JNK1 in the FGF21 Pathway
    Julieta Díaz-Delfín, Elayne Hondares, Roser Iglesias, Marta Giralt, Carmé Caelles, Francesc Villarroya · 2012 · Endocrinology
  89. Functional Role of PPARs in Ruminants: Potential Targets for Fine-Tuning Metabolism during Growth and Lactation
    Massimo Bionaz, Shuowen Chen, Muhammad Jawad Khan, Juan J. Loor · 2013 · PPAR Research
  90. Molecular determinants of FGF‐21 activity—synergy and cross‐talk with PPARγ signaling
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  91. Serum Fibroblast Growth Factor-21 Levels Are Associated With Carotid Atherosclerosis Independent of Established Cardiovascular Risk Factors
    Wing Sun Chow, Aimin Xu, Yu Cho Woo, Annette W.K. Tso, S. Cheung, Carol Ho-Yan Fong, Hung‐Fat Tse, Ming Tak Chau, Bernard M.Y. Cheung, Karen S.L. Lam · 2013 · Arteriosclerosis Thrombosis and Vascular Biology
  92. Sodium Butyrate Stimulates Expression of Fibroblast Growth Factor 21 in Liver by Inhibition of Histone Deacetylase 3
    Huating Li, Zhan‐Guo Gao, Jin Zhang, Xin Ye, Aimin Xu, Jianping Ye, Weiping Jia · 2012 · Diabetes
  93. Bile acid signaling in the regulation of whole body metabolic and immunological homeostasis
    Wei Ping Jia, Yitao Li, Kenneth Chat-Pan Cheung, Xiaojiao Zheng · 2023 · Science China Life Sciences
  94. Loss of hepatic chaperone‐mediated autophagy accelerates proteostasis failure in aging
    Jaime Laurel Schneider, Joan Villarroya, Antonio M. Díaz-Carretero, Bindi Patel, Aleksandra Malgorzata Urbanska, Mia M. Thi, Francesc Villarroya, Laura Santambrogio, Ana María Cuervo · 2015 · Aging Cell
  95. Serum selenoprotein P levels in patients with type 2 diabetes and prediabetes: implications for insulin resistance, inflammation, and atherosclerosis
    Yang, S. J., Hwang, S. Y., Choi, H. Y., Yoo, H. J., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., Choi, D. S., Choi, K. M. · 2011 · The Journal of Clinical Endocrinology & Metabolism
  96. Crosstalk between adipokines and myokines in fat browning
    Amaia Rodríguez, Sara Becerril, Silvia Ezquerro, Leire Méndez-Giménez, Gema Frühbeck · 2016 · Acta Physiologica
  97. Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes
    Iizuka, Katsumi, Takeda, Jun, Horikawa, Yukio · 2009 · FEBS Letters
  98. Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice
    Ye, Dewei, Wang, Yudong, Li, Huating, Jia, Weiping, Man, Kwan, Lo, Chung Mau, Wang, Yu, Lam, Karen S.L., Xu, Aimin · 2014 · Hepatology
  99. Mechanisms of FGFR-mediated carcinogenesis
    Imran Ahmad, Tomoko Iwata, Hing Y. Leung · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  100. FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation
    Xinle Wu, Hongfei Ge, B. Lemon, S. Vonderfecht, Jennifer Weiszmann, R. Hecht, Jamila Gupte, Todd Hager, Zhu-Lun Wang, R. Lindberg et al. · 2009 · Journal of Biological Chemistry