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The Relative Antioxidant Activities of Plant-Derived Polyphenolic Flavonoids
Abstract
The relative antioxidant activities, against radicals generated in the aqueous phase, of a range of plant-derived polyphenolic flavonoids, constituents of fruit, vegetables, tea and wine, have been assessed. The results show that compounds such as quercetin and cyanidin, with 3',4' dihydroxy substituents in the B ring and conjugation between the A and B rings, have antioxidant potentials four times that of Trolox, the vitamin E analogue. Removing the ortho-dihydroxy substitution, as in kaempferol, or the potential for electron delocalisation by reducing the 2,3 double bond in the C ring, as in catechin and epicatechin, decreases the antioxidant activity by more than 50%, but these structures are still more effective than alpha-tocopherol or ascorbate. The relative significance of the positions and extents of hydroxylation of the A and B rings to the total antioxidant activity of these plant polyphenolics is demonstrated.
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Metadata
- Authors
- Rice-evans, C. A., Miller, N. J., Bolwell, P. G., Bramley, P. M., & Pridham, J. B.
- Venue
- Free Radical Research
- Publisher
- Informa UK Limited
- Published
- 1995-01
- Volume
- 22
- Issue
- 4
- Pages
- 375-383
- ISSN
- 1029-2470 (ISSN-L)
- 1071-5762
- OpenAlex
- W2146346788
- Cited by
- 2,163
- References
- 0
- FWCI
- 16.70
- Type
- journal article
- Language
- en
- Open access
- closed
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