Gut Microbiota in Obesity and Undernutrition

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444 · see citing works

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041 · see citing works

Human gut microbes associated with obesity

Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785 · see citing works

Maternal and child undernutrition and overweight in low-income and middle-income countries

Black, R. E., Victora, C. G., Walker, S. P., Bhutta, Z. A., Christian, P., de Onis, M., Ezzati, M., Grantham-McGregor, S., Katz, J., Martorell, R., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)60937-x · Cited by 8,475 · see citing works

A metagenome-wide association study of gut microbiota in type 2 diabetes

Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., et al. (2012) · Nature · doi:10.1038/nature11450 · Cited by 6,762 · see citing works

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760 · see citing works

Central nervous system control of food intake

Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451 · see citing works

The gut microbiota as an environmental factor that regulates fat storage

Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245 · see citing works

Obesity alters gut microbial ecology

Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504978102 · Cited by 6,176 · see citing works

Richness of human gut microbiome correlates with metabolic markers

Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662 · see citing works

Adipokines in inflammation and metabolic disease

Ouchi, N., Parker, J. L., Lugus, J. J., & Walsh, K. (2011) · Nature Reviews Immunology · doi:10.1038/nri2921 · Cited by 4,625 · see citing works

Cross-talk between <i>Akkermansia muciniphila</i> and intestinal epithelium controls diet-induced obesity

Everard, A., Belzer, C., Geurts, L., Ouwerkerk, J. P., Druart, C., Bindels, L. B., Guiot, Y., Derrien, M., Muccioli, G. G., Delzenne, N. M., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219451110 · Cited by 4,511 · see citing works

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., et al. (2013) · Science · doi:10.1126/science.1241214 · Cited by 3,788 · see citing works

Biology of Incretins: GLP-1 and GIP

Baggio, L. L., & Drucker, D. J. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.054 · Cited by 3,639 · see citing works

Differential Significance of Plasma Visfatin Concentrations according to Adiposity in Children and Adolescents

Kim, H. J., Park, S. Y., Choi, Y. J., Han, S. J., Lee, K. W., & Kim, D. J. (2013) · Hormone Research in Paediatrics · doi:10.1159/000348848 · Cited by 3,061 · see citing works

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

Turnbaugh, P. J., Ridaura, V. K., Faith, J. J., Rey, F. E., Knight, R., & Gordon, J. I. (2009) · Science Translational Medicine · doi:10.1126/scitranslmed.3000322 · Cited by 3,058 · see citing works

Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome

Vrieze, A., Van Nood, E., Holleman, F., Salojärvi, J., Kootte, R. S., Bartelsman, J. F. W. M., Dallinga–Thie, G. M., Ackermans, M. T., Serlie, M. J., Oozeer, R., et al. (2012) · Gastroenterology · doi:10.1053/j.gastro.2012.06.031 · Cited by 2,913 · see citing works

Central nervous system control of food intake and body weight

Morton, G. J., Cummings, D. E., Baskin, D. G., Barsh, G. S., & Schwartz, M. W. (2006) · Nature · doi:10.1038/nature05026 · Cited by 2,503 · see citing works

Microbiota and SCFA in lean and overweight healthy subjects

Schwiertz, A., Taras, D., Schäfer, K., Beijer, S., Bos, N. A., Donus, C., & Hardt, P. D. (2010) · Obesity · doi:10.1038/oby.2009.167 · Cited by 2,457 · see citing works

The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

Brown, A. J., Goldsworthy, S. M., Barnes, A. A., Eilert, M. M., Tcheang, L., Daniels, D., Muir, A. I., Wigglesworth, M. J., Kinghorn, I., Fraser, N. J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211609200 · Cited by 2,409 · see citing works

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2

Tolhurst, G., Heffron, H., Lam, Y. S., Parker, H. E., Habib, A. M., Diakogiannaki, E., Cameron, J., Grosse, J., Reimann, F., & Gribble, F. M. (2012) · Diabetes · doi:10.2337/db11-1019 · Cited by 2,404 · see citing works

Psychosomatic medicine in Germany: more timely than ever

Zipfel, S., Herzog, W., Kruse, J., & Henningsen, P. (2016) · Psychotherapy and Psychosomatics · doi:10.1159/000447701 · Cited by 2,323 · see citing works

Butyrate improves insulin sensitivity and increases energy expenditure in mice

Gao, Z., Yin, J., Zhang, J., Ward, R. E., Martin, R. J., Lefevre, M., Cefalu, W. T., & Ye, J. (2009) · Diabetes · doi:10.2337/db08-1637 · Cited by 2,204 · see citing works

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

De Vadder, F., Kovatcheva-Datchary, P., Goncalves, D., Vinera, J., Zitoun, C., Duchampt, A., Bäckhed, F., & Mithieux, G. (2014) · Cell · doi:10.1016/j.cell.2013.12.016 · Cited by 2,200 · see citing works

Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium

Derrien, M., Vaughan, E. E., Plugge, C. M., & de Vos, W. M. (2004) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/ijs.0.02873-0 · Cited by 2,094 · see citing works

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

Sender, R., Fuchs, S., & Milo, R. (2016) · Cell · doi:10.1016/j.cell.2016.01.013 · Cited by 2,050 · see citing works

Changes in Energy Expenditure Resulting from Altered Body Weight

Leibel, R. L., Rosenbaum, M., & Hirsch, J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321001 · Cited by 2,012 · see citing works

A role for glucagon-like peptide-1 in the central regulation of feeding

Turton, M. D., O'Shea, D., Gunn, I., Beak, S. A., Edwards, C. M. B., Meeran, K., Choi, S. J., Taylor, G. M., Heath, M. M., Lambert, P. D., et al. (1996) · Nature · doi:10.1038/379069a0 · Cited by 1,950 · see citing works

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia

Cani, P. D., Neyrinck, A. M., Fava, F., Knauf, C., Burcelin, R., Tuohy, K. M., Gibson, G. R., & Delzenne, N. M. (2007) · Diabetologia · doi:10.1007/s00125-007-0791-0 · Cited by 1,776 · see citing works

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

Frost, G., Sleeth, M. L., Sahuri-Arisoylu, M., Lizarbe, B., Cerdan, S., Brody, L., Anastasovska, J., Ghourab, S., Hankir, M., Zhang, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms4611 · Cited by 1,771 · see citing works

The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion

Wren, A. M., Small, C. J., Ward, H. L., Murphy, K. G., Dakin, C. L., Taheri, S., Kennedy, A. R., Roberts, G. H., Morgan, D. G. A., Ghatei, M. A., et al. (2000) · Endocrinology · doi:10.1210/endo.141.11.7873 · Cited by 1,593 · see citing works

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

Hildebrandt, M. A., Hoffmann, C., Sherrill–Mix, S. A., Keilbaugh, S. A., Hamady, M., Chen, Y., Knight, R., Ahima, R. S., Bushman, F., & Wu, G. D. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.08.042 · Cited by 1,576 · see citing works

The cellular and signaling networks linking the immune system and metabolism in disease

Osborn, O., & Olefsky, J. M. (2012) · Nature Medicine · doi:10.1038/nm.2627 · Cited by 1,551 · see citing works

The GLUT4 Glucose Transporter

Huang, S., & Czech, M. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.03.006 · Cited by 1,391 · see citing works

Gut Microbiota and Metabolic Endotoxemia in Young Obese Mexican Subjects

Radilla-Vázquez, R. B., Parra‐Rojas, I., Martínez-Hernández, N. E., Márquez‐Sandoval, F., Illades‐Aguiar, B., & Castro-Alarcón, N. (2016) · Obesity Facts · doi:10.1159/000442479 · Cited by 1,197 · see citing works

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., et al. (2013) · Science · doi:10.1126/science.1229000 · Cited by 1,173 · see citing works

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

den Besten, G., Bleeker, A., Gerding, A., van Eunen, K., Havinga, R., van Dijk, T. H., Oosterveer, M. H., Jonker, J. W., Groen, A. K., Reijngoud, D.-J., et al. (2015) · Diabetes · doi:10.2337/db14-1213 · Cited by 1,125 · see citing works

Short chain fatty acids in the human colon.

Cummings, J. H. (1981) · Gut · doi:10.1136/gut.22.9.763 · Cited by 1,050 · see citing works

Nutrient sensing and inflammation in metabolic diseases

Hotamisligil, G. S., & Erbay, E. (2008) · Nature Reviews Immunology · doi:10.1038/nri2449 · Cited by 1,040 · see citing works

Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity

Liou, A. P., Paziuk, M., Luevano, J.-M., Machineni, S., Turnbaugh, P. J., & Kaplan, L. M. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3005687 · Cited by 1,007 · see citing works

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models

Murphy, E. F., Cotter, P. D., Healy, S., Marques, T. M., O’Sullivan, Ó., Fouhy, F., Clarke, S. F., O’Toole, P. W., Quigley, E. M. M., Stanton, C., et al. (2010) · Gut · doi:10.1136/gut.2010.215665 · Cited by 942 · see citing works

Monitoring Bacterial Community of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients

Armougom, F., Henry, M., Vialettes, B., Raccah, D., & Raoult, D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007125 · Cited by 905 · see citing works

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

Psichas, A., Sleeth, M. L., Murphy, K. G., Brooks, L., Bewick, G. A., Hanyaloglu, A. C., Ghatei, M. A., Bloom, S. R., & Frost, G. (2015) · International Journal of Obesity · doi:10.1038/ijo.2014.153 · Cited by 886 · see citing works

The gut microbiota and obesity: from correlation to causality

Zhao, L. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3089 · Cited by 847 · see citing works

Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

Cani, P. D., Lecourt, E., Dewulf, E. M., Sohet, F. M., Pachikian, B. D., Naslain, D., Backer, F. D., Neyrinck, A. M., & Delzenne, N. M. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28095 · Cited by 763 · see citing works

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

Blanton, L. V., Charbonneau, M. R., Salih, T., Barratt, M. J., Venkatesh, S., Ilkaveya, O., Subramanian, S., Manary, M. J., Trehan, I., Jorgensen, J. M., et al. (2016) · Science · doi:10.1126/science.aad3311 · Cited by 735 · see citing works

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

Xiong, Y., Miyamoto, N., Shibata, K., Valasek, M. A., Motoike, T., Kedzierski, R. M., & Yanagisawa, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2637002100 · Cited by 731 · see citing works

Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults

Parnell, J. A., & Reimer, R. A. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27465 · Cited by 728 · see citing works

Therapeutic Potential of Fecal Microbiota Transplantation

Smits, L. P., Bouter, K. E. C., de Vos, W. M., Borody, T. J., & Nieuwdorp, M. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.08.058 · Cited by 717 · see citing works

Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis

Odegaard, J. I., & Chawla, A. (2013) · Science · doi:10.1126/science.1230721 · Cited by 643 · see citing works

Insights into the role of the microbiome in obesity and type 2 diabetes

Hartstra, A. V., Bouter, K. E. C., Bäckhed, F., & Nieuwdorp, M. (2015) · Diabetes Care · doi:10.2337/dc14-0769 · Cited by 641 · see citing works

Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans

Fernandes, J., Su, W., Rahat-Rozenbloom, S., Wolever, T. M. S., & Comelli, E. M. (2014) · Nutrition &amp; Diabetes · doi:10.1038/nutd.2014.23 · Cited by 628 · see citing works

Ghrelin and the short- and long-term regulation of appetite and body weight

Cummings, D. E. (2006) · Physiology &amp; Behavior · doi:10.1016/j.physbeh.2006.05.022 · Cited by 620 · see citing works

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

den Besten, G., Lange, K., Havinga, R., van Dijk, T. H., Gerding, A., van Eunen, K., Müller, M. M., Groen, A. K., Hooiveld, G. J. E. J., Bakker, B. M., et al. (2013) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00265.2013 · Cited by 606 · see citing works

The inhibitory effects of peripheral administration of peptide YY3–36 and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal–brainstem–hypothalamic pathway

Abbott, C. R., Monteiro, M. P., Small, C. J., Sajedi, A., Smith, K. L., Parkinson, J. R. C., Ghatei, M. A., & Bloom, S. R. (2005) · Brain Research · doi:10.1016/j.brainres.2005.03.011 · Cited by 599 · see citing works

Genetic identification of a neural circuit that suppresses appetite

Carter, M. E., Soden, M. E., Zweifel, L. S., & Palmiter, R. D. (2013) · Nature · doi:10.1038/nature12596 · Cited by 587 · see citing works

Gut Microbiota Composition in Male Rat Models under Different Nutritional Status and Physical Activity and Its Association with Serum Leptin and Ghrelin Levels

Queipo-Ortuño, M. I., Seoane, L. M., Murri, M., Pardo, M., Gomez-Zumaquero, J. M., Cardona, F., Casanueva, F., & Tinahones, F. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065465 · Cited by 497 · see citing works

Pancreatic Polypeptide Reduces Appetite and Food Intake in Humans

Batterham, R. L., Le Roux, C. W., Cohen, M. A., Park, A. J., Ellis, S. M., Patterson, M., Frost, G. S., Ghatei, M. A., & Bloom, S. R. (2003) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2003-030630 · Cited by 496 · see citing works

Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine

Karaki, S.-I., Mitsui, R., Hayashi, H., Kato, I., Sugiya, H., Iwanaga, T., Furness, J., & Kuwahara, A. (2006) · Cell and Tissue Research · doi:10.1007/s00441-005-0140-x · Cited by 465 · see citing works

Central Control of Body Weight and Appetite

Woods, S. C., & D’Alessio, D. A. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1630 · Cited by 460 · see citing works

Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents

Zhou, J., Martin, R. J., Tulley, R. T., Raggio, A. M., McCutcheon, K. L., Shen, L., Danna, S. C., Tripathy, S., Hegsted, M., & Keenan, M. J. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90637.2008 · Cited by 460 · see citing works

Physiological adaptations to weight loss and factors favouring weight regain

Greenway, F. L. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.59 · Cited by 431 · see citing works

Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals

Million, M., Angelakis, E., Paul, M., Armougom, F., Leibovici, L., & Raoult, D. (2012) · Microbial Pathogenesis · doi:10.1016/j.micpath.2012.05.007 · Cited by 430 · see citing works

Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes

Kong, L.-C., Tap, J., Aron-Wisnewsky, J., Pelloux, V., Basdevant, A., Bouillot, J.-L., Zucker, J.-D., Doré, J., & Clément, K. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.058743 · Cited by 416 · see citing works

Weight Gain After Fecal Microbiota Transplantation

Alang, N., & Kelly, C. R. (2015) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofv004 · Cited by 403 · see citing works

Oligofructose Promotes Satiety in Rats Fed a High‐Fat Diet: Involvement of Glucagon‐Like Peptide‐1

Cani, P. D., Neyrinck, A. M., Maton, N., & Delzenne, N. M. (2005) · Obesity Research · doi:10.1038/oby.2005.117 · Cited by 382 · see citing works

Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth

Breton, J., Tennoune, N., Lucas, N., Francois, M., Legrand, R., Jacquemot, J., Goichon, A., Guérin, C., Peltier, J., Pestel-Caron, M., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2015.10.017 · Cited by 321 · see citing works

Early administration of Bifidobacterium breve to preterm infants: randomised controlled trial

Kitajima, H., Sumida, Y., Tanaka, R., Yuki, N., Takayama, H., & Fujimura, M. (1997) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/fn.76.2.f101 · Cited by 315 · see citing works

Weight gain in anorexia nervosa does not ameliorate the faecal microbiota, branched chain fatty acid profiles and gastrointestinal complaints

Mack, I., Cuntz, U., Grämer, C., Niedermaier, S., Pohl, C., Schwiertz, A., Zimmermann, K., Zipfel, S., Enck, P., & Penders, J. (2016) · Scientific Reports · doi:10.1038/srep26752 · Cited by 313 · see citing works

Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men

Näslund, E. B., Gutniak, M., Skogar, S., Rössner, S., & Hellström, P. M. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.3.525 · Cited by 307 · see citing works

The gut as the largest endocrine organ in the body

Ahlman, H. K., & Nilsson, O. (2001) · Annals of Oncology · doi:10.1093/annonc/12.suppl_2.s63 · Cited by 256 · see citing works

Gut Dysbiosis in Patients with Anorexia Nervosa

Morita, C., Tsuji, H., Hata, T., Gondo, M., Takakura, S., Kawai, K., Yoshihara, K., Ogata, K., Nomoto, K., Miyazaki, K., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0145274 · Cited by 238 · see citing works

Childhood undernutrition, the gut microbiota, and microbiota-directed therapeutics

Blanton, L. V., Barratt, M. J., Charbonneau, M. R., Ahmed, T., & Gordon, J. I. (2016) · Science · doi:10.1126/science.aad9359 · Cited by 234 · see citing works

Gut microbiota and energy balance: role in obesity

Blaut, M. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665114001700 · Cited by 232 · see citing works

Central leptin modulates behavioral and neural responsivity to CCK

Emond, M. H., Schwartz, G. J., Ladenheim, E. E., & Moran, T. H. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.276.5.r1545 · Cited by 225 · see citing works

Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota

Bauer, P. V., Hamr, S. C., & Duca, F. A. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2083-z · Cited by 217 · see citing works

Muscle wasting: The gut microbiota as a new therapeutic target?

Bindels, L. B., & Delzenne, N. M. (2013) · The International Journal of Biochemistry &amp; Cell Biology · doi:10.1016/j.biocel.2013.06.021 · Cited by 198 · see citing works

New Insights in Anorexia Nervosa

Gorwood, P. A. P. M., Blanchet, C., Chartrel, N., Duclos, J., Déchelotte, P., Hanachi, M., Fetissov, S. O., Godart, N. T., Melchior, J., Ramoz, N., et al. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00256 · Cited by 193 · see citing works

Related actions of probiotics and antibiotics on gut microbiota and weight modification

Angelakis, E., Merhej, V., & Raoult, D. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(13)70179-8 · Cited by 190 · see citing works

Peptide YY and Proglucagon mRNA Expression Patterns and Regulation in the Gut

Zhou, J. F., Hegsted, M., McCutcheon, K. L., Keenan, M. J., Xi, X., Raggio, A. M., & Martin, R. J. (2006) · Obesity · doi:10.1038/oby.2006.77 · Cited by 188 · see citing works

The Human Gut Microbiota and Undernutrition

Gordon, J. I., Dewey, K. G., Mills, D. A., & Medzhitov, R. M. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004347 · Cited by 186 · see citing works

Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi

Kerac, M., Bunn, J., Seal, A., Thindwa, M., Tomkins, A. M., Sadler, K., Bahwere, P., & Collins, S. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60884-9 · Cited by 183 · see citing works

Cholecystokinin

Chandra, R., & Liddle, R. A. (2007) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3280122850 · Cited by 181 · see citing works

Intestinal microbiota and type 2 diabetes: From mechanism insights to therapeutic perspective

Han, J.-L., & Lin, H. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i47.17737 · Cited by 179 · see citing works

Resistance to treatment and change in anorexia nervosa: a clinical overview

Daga, G. A., Amianto, F., Delsedime, N., Bacco, C. D., & Fassino, S. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-294 · Cited by 178 · see citing works

Nitrogen losses from the human small bowel: obligatory losses and the effect of physical form of food.

Chacko, A., & Cummings, J. H. (1988) · Gut · doi:10.1136/gut.29.6.809 · Cited by 176 · see citing works

Resting metabolic rate is associated with hunger, self-determined meal size, and daily energy intake and may represent a marker for appetite

Caudwell, P., Finlayson, G., Gibbons, C., Hopkins, M., King, N., Näslund, E., & Blundell, J. E. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.029975 · Cited by 165 · see citing works

Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota

Mishra, A. K., Dubey, V., & Ghosh, A. R. (2016) · Metabolism · doi:10.1016/j.metabol.2015.10.008 · Cited by 161 · see citing works

Appetite and Cancer-Associated Anorexia: A Review

Davis, M. P., Dreicer, R., Walsh, D., Lagman, R. L., & LeGrand, S. B. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.03.103 · Cited by 152 · see citing works

Mechanisms of CCK signaling from gut to brain

Raybould, H. E. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.09.006 · Cited by 151 · see citing works

Alterations of gut barrier and gut microbiota in food restriction, food deprivation and protein-energy wasting

Genton, L., Cani, P. D., & Schrenzel, J. (2015) · Clinical Nutrition · doi:10.1016/j.clnu.2014.10.003 · Cited by 148 · see citing works

Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats

Dakin, C. L., Small, C. J., Park, A. J., Seth, A., Ghatei, M. A., & Bloom, S. R. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00233.2002 · Cited by 142 · see citing works

The autonomic nervous system, adipose tissue plasticity, and energy balance

Pénicaud, L., Cousin, B., Leloup, C., Lorsignol, A., & Casteilla, L. (2000) · Nutrition · doi:10.1016/s0899-9007(00)00427-5 · Cited by 136 · see citing works

Taste perception, associated hormonal modulation, and nutrient intake

Loper, H., Sala, M. L., Dotson, C. D., & Steinle, N. (2015) · Nutrition Reviews · doi:10.1093/nutrit/nuu009 · Cited by 132 · see citing works

Diversity of the genus Lactobacillus revealed by comparative genomics of five species

Canchaya, C. A., Claesson, M. J., Fitzgerald, G. F., van Sinderen, D., & O’Toole, P. W. (2006) · Microbiology · doi:10.1099/mic.0.29140-0 · Cited by 123 · see citing works

Role of Cholecystokinin in the Regulation of Gastrointestinal Motility

Grider, J. R. (1994) · Journal of Nutrition · doi:10.1093/jn/124.suppl_8.1334s · Cited by 121 · see citing works

Growth during the first 6 months of life in infants using formula enriched with Lactobacillus rhamnosus GG: double‐blind, randomized trial

Vendt, N., Grünberg, H., Tuure, T., Malminiemi, O., Wuolijoki, E., Tillmann, V., Sepp, E., & Korpela, R. (2006) · Journal of Human Nutrition and Dietetics · doi:10.1111/j.1365-277x.2006.00660.x · Cited by 120 · see citing works

Transgenic and Recombinant Resistin Impair Skeletal Muscle Glucose Metabolism in the Spontaneously Hypertensive Rat

Pravenec, M., Kazdová, L., Landa, V., Zı́dek, V., Mlejnek, P., Jansa, P., Wang, J., Qi, N., & Kurtz, T. W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304869200 · Cited by 119 · see citing works

Adipose tissue inflammation and cancer cachexia: Possible role of nuclear transcription factors

Júnior, M. L. B., Peres, S. B., McDonald, M. E., de Alcântara, P. S. M., Oliván, M., Otoch, J. P., Farmer, S. R., & Seelaender, M. C. L. (2011) · Cytokine · doi:10.1016/j.cyto.2011.10.008 · Cited by 118 · see citing works

Resistance to treatment in eating disorders: a critical challenge

Fassino, S., & Daga, G. A. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-282 · Cited by 109 · see citing works

Feasibility studies to control acute diarrhoea in children by feeding fermented milk preparations Actimel and Indian Dahi

Agarwal, K., & Bhasin, S. (2002) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601664 · Cited by 108 · see citing works

The Human Experience With Ghrelin Administration

Garin, M. C., Burns, C. M., Kaul, S., & Cappola, A. R. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-4247 · Cited by 107 · see citing works

Gut microbiota, nutrient sensing and energy balance

Duca, F. A., & Lam, T. K. T. (2014) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12340 · Cited by 103 · see citing works

Nutrient, Neural and Endocrine Control of Glucagon-like Peptide Secretion

Dubé, P. E., & BRUBAKER, P. L. (2004) · Hormone and Metabolic Research · doi:10.1055/s-2004-826159 · Cited by 100 · see citing works

Manipulation of the Gut Microbiota as a Novel Treatment Strategy for Gastrointestinal Disorders

Foxx–Orenstein, A. E., & Chey, W. D. (2012) · The American Journal of Gastroenterology Supplements · doi:10.1038/ajgsup.2012.8 · Cited by 76 · see citing works

Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release

Nakata, M., Okada, T., Ozawa, K., & Yada, T. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.12.134 · Cited by 74 · see citing works

The influence of leptin on early life programming of obesity

Stocker, C. J., & Cawthorne, M. A. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2008.06.004 · Cited by 67 · see citing works

Food-related gastrointestinal signals activate caudal brainstem neurons expressing both NMDA and AMPA receptors

Berthoud, H., Earle, T., Zheng, H., Patterson, L. M., & Phifer, C. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02826-8 · Cited by 66 · see citing works

Role of Intestinal Microbiome in Lipid and Glucose Metabolism in Diabetes Mellitus

van Olden, C. C., Groen, A. K., & Nieuwdorp, M. (2015) · Clinical Therapeutics · doi:10.1016/j.clinthera.2015.03.008 · Cited by 57 · see citing works

Are Astrocytes the Pressure-Reservoirs of Lactate in the Brain?

Kasparov, S. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.11.001 · Cited by 54 · see citing works

Effects of gastric emptying on the postprandial ghrelin response

Blom, W. A. M., Lluch, A., Vinoy, S., Stafleu, A., van den Berg, R., Holst, J. J., Kok, F. J., & Hendriks, H. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00238.2005 · Cited by 52 · see citing works

Gut feelings: A role for the intestinal microbiota in anorexia nervosa?

Kleiman, S. C., Carroll, I. M., Tarantino, L. M., & Bulik, C. M. (2015) · International Journal of Eating Disorders · doi:10.1002/eat.22394 · Cited by 46 · see citing works

Alleviation of high fat diet‐induced obesity by oligofructose in gnotobiotic mice is independent of presence of Bifidobacterium longum

Woting, A., Pfeiffer, N., Hanske, L., Loh, G., Klaus, S., & Blaut, M. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500249 · Cited by 44 · see citing works

Hypothalamic Cocaine- and Amphetamine-Regulated Transcript (CART) and Agouti-Related Protein (AgRP) Neurons Coexpress the NOP1 Receptor and Nociceptin Alters CART and AgRP Release

Bewick, G. A., Dhillo, W. S., Darch, S. J., Murphy, K. G., Gardiner, J., Jethwa, P. H., Kong, W. M., Ghatei, M. A., & Bloom, S. R. (2005) · Endocrinology · doi:10.1210/en.2004-1659 · Cited by 43 · see citing works

A role for the gut microbiota in energy harvesting?

Tremaroli, V., Kovatcheva-Datchary, P., & Bäckhed, F. (2010) · Gut · doi:10.1136/gut.2010.223594 · Cited by 38 · see citing works

Ghrelin, A Novel Peptide Hormone in the Regulation of Energy Balance and Cardiovascular Function

Ledderose, C., Kreth, S., & Beiras-Fernández, A. (2011) · Recent Patents on Endocrine Metabolic & Immune Drug Discovery · doi:10.2174/187221411794351897 · Cited by 35 · see citing works

Rats lighten up with MCH antagonist

Schwartz, M. W., & Gelling, R. W. (2002) · Nature Medicine · doi:10.1038/nm0802-779 · Cited by 33 · see citing works

Role of gastrointestinal hormones in feeding behavior and obesity treatment

Kairupan, T. S., Amitani, H., Cheng, K., Runtuwene, J., Asakawa, A., & Inui, A. (2015) · Journal of Gastroenterology · doi:10.1007/s00535-015-1118-4 · Cited by 30 · see citing works

Gut Microbiota and Energy Expenditure in Health and Obesity

Bakker, G. J., Zhao, J., Herrema, H., & Nieuwdorp, M. (2015) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000000363 · Cited by 27 · see citing works

The gut sensor as regulator of body weight

Reinehr, T., & Roth, C. L. (2014) · Endocrine · doi:10.1007/s12020-014-0518-1 · Cited by 26 · see citing works

Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions

Ristori, M. V., Quagliariello, A., Reddel, S., Ianiro, G., Vicari, S., Gasbarrini, A., & Putignani, L. (2019) · Nutrients · doi:10.3390/nu11112812 · Cited by 214 · see citing works

Causes, assessment and treatment of malnutrition in older people

Willis, H. (2017) · Nursing Older People · doi:10.7748/nop.2017.e883 · Cited by 18 · see citing works

Malnutrition

Gearman, L., & Larson‐Nath, C. M. (2022) · CRC Press eBooks · doi:10.1201/9781003147855-10

Malnutrition in the elderly — prevalence, causes and corrective strategies

Volkert, D. (2002) · Clinical Nutrition · doi:10.1016/s0261-5614(02)80014-0 · Cited by 32 · see citing works

Using Global Criteria to Detect Malnutrition: Application in Disease States

Kirsch, R., Matthews, K., & Williams, V. (2019) · Nutrition in Clinical Practice · doi:10.1002/ncp.10444 · Cited by 18 · see citing works

Undernutrition in children

King, F. S., & Burgess, A. P. (1993) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780192622334.003.0016