Interoceptive awareness enhances neural activity during empathy
Open accessAbstract
Empathy is a multicomponent function that includes sensorimotor, affective, and cognitive components. Although especially the affective component may implicate interoception and interoceptive awareness, the impact of interoception on empathy has never been evaluated behaviorally or neurophysiologically. Here, we tested how a preceding period of interoceptive awareness impacts and modulates neural activity during subsequent empathy. We used functional magnetic resonance imaging (fMRI) and measured the sequential interaction between interoception and empathy using fMRI in 18 healthy subjects. We found that the preceding interoceptive awareness period significantly enhanced neural activity during empathy in bilateral anterior insula and various cortical midline regions. The enhancement of neural activity during empathy in both interoceptive and empathy networks by preceding interoceptive awareness suggests a close relationship between interoception and empathy; thereby, interoception seems to be implicated to yielding empathy. Hum Brain Mapp, 2013. © 2012 Wiley Periodicals, Inc.
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Data based on fMRI and EEG show similar patterns of brain activity during both interoceptive tasks and emotion elicitation.
“On the one hand, data based on fMRI and EEG analysis show similar patterns of brain activity during both interoceptive tasks and emotion elicitation [5,38,39,40].”
From Interoceptive Ability and Emotion Regulation in Mind–Body Interventions: An Integrative Review (2024) · cites this paper as [40]
The Introduction (page not available) describes considerable regional overlap between interoception and empathy, and the paper’s fMRI results report insula activity during interoception and empathy. It also cites an EEG study finding that a heartbeat-evoked potential varies during empathy, but does not say EEG showed similar patterns of brain activity across interoceptive tasks and emotion elicitation. The claim overstates what this source establishes for EEG and for emotion elicitation generally. (LLM, conf=0.83)
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- Authors
- Ernst, J., Northoff, G., Böker, H., Seifritz, E., & Grimm, S.
- Affiliations
- University Hospital Zurich (CH)
- University of Ottawa (CA)
- University of Zurich (CH)
- Venue
- Human Brain Mapping
- Publisher
- Wiley
- Published
- 2012-02-22
- Volume
- 34
- Issue
- 7
- Pages
- 1615-1624
- ISSN
- 1065-9471 (ISSN-L)
- 1097-0193
- PMC
- PMC6869919
- OpenAlex
- W2161300291
- Semantic Scholar
- d2ef1c8e568c849e4153796cdb9334d45c751aae
- Cited by
- 107
- References
- 69
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 8 · 2023: 7 · 2022: 6 · 2021: 18 · 2020: 11 · 2019: 11 · 2018: 7 · 2017: 6 · 2016: 6 · 2015: 3 · 2014: 9 · 2013: 1 · 2012: 2
- FWCI
- 7.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Human Brain Mapping (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eli Lilly and Company
- Hope for Depression Research Foundation
- Topics
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Empathy and Medical Education
- Keywords
- interoceptive awareness, interoception, empathy, affective empathy, anterior insula, neuronal activity modulation
- MeSH terms
- Adult, Awareness, Brain Mapping, Cerebral Cortex, Empathy, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Neural Pathways, Oxygen, Photic Stimulation, Time Factors, Young Adult
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