Flavonoids: Nutraceutical Potential for Counteracting Muscle Atrophy
Open accessAbstract
Skeletal muscle plays a vital role in the conversion of chemical energy into physical force. Muscle atrophy, characterized by a reduction in muscle mass, is a symptom of chronic disease (cachexia), aging (sarcopenia), and muscle disuse (inactivity). To date, several trials have been conducted to prevent and inhibit muscle atrophy development; however, few interventions are currently available for muscle atrophy. Recently, food ingredients, plant extracts, and phytochemicals have received attention as treatment sources to prevent muscle wasting. Flavonoids are bioactive polyphenol compounds found in foods and plants. They possess diverse biological activities, including anti-obesity, anti-diabetes, anti-cancer, anti-oxidation, and anti-inflammation. The effects of flavonoids on muscle atrophy have been investigated by monitoring molecular mechanisms involved in protein turnover, mitochondrial activity, and myogenesis. This review summarizes the reported effects of flavonoids on sarcopenia, cachexia, and disuse muscle atrophy, thus, providing an insight into the understanding of the associated molecular mechanisms.
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Evidence from preclinical studies reveals nutraceuticals play a significant role in maintaining muscle health and are potential therapeutic agents in a broad range of muscle atrophy models.
“Evidence from various preclinical studies has revealed that nutraceuticals play a significant role in maintaining muscle health and emerge as potential therapeutic agents in a broad range of muscle atrophy models [17,18].”
From Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy (2021) · cites this paper as [17]
Phytochemicals play an essential role in the prevention and treatment of muscle atrophy, especially in reducing muscle protein degradation and promoting muscle protein synthesis.
“Collectively, phytochemicals play an essential role in the prevention and treatment of muscle atrophy, especially in reducing muscle protein degradation and promoting muscle protein synthesis [17,18].”
From Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy (2021) · cites this paper as [17]
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Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Nishita, M., Park, S.-Y., Nishio, T., Kamizaki, K., Wang, Z., Tamada, K., Takumi, T., Hashimoto, R., Otani, H., Pazour, G. J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-016-0028-x · Cited by 15,947 · see citing works
Chemistry and Biological Activities of Flavonoids: An Overview
Kumar, S., & Pandey, A. K. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/162750 · Cited by 5,178 · see citing works
Skeletal muscle: A brief review of structure and function
Frontera, W. R., & Ochala, J. (2015) · Calcified Tissue International · doi:10.1007/s00223-014-9915-y · Cited by 1,758 · see citing works
A Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse
Moser, A. R., Pitot, H. C., & Dove, W. F. (1990) · Science · doi:10.1126/science.2296722 · Cited by 1,591 · see citing works
Rommel, C., Bodine, S. C., Clarke, B. A., Rossman, R., Nunez, L., Stitt, T. N., Yancopoulos, G. D., & Glass, D. J. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1009 · Cited by 1,583 · see citing works
Antioxidant and prooxidant properties of flavonoids
Procházková, D., Boušová, I., & Wilhelmová, N. (2011) · Fitoterapia · doi:10.1016/j.fitote.2011.01.018 · Cited by 1,572 · see citing works
Cellular and molecular mechanisms of muscle atrophy
Bonaldo, P., & Sandri, M. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.010389 · Cited by 1,284 · see citing works
Flavonoids as anti-inflammatory agents
Serafini, M., Peluso, I., & Raguzzini, A. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s002966511000162x · Cited by 826 · see citing works
Skeletal muscle loss: cachexia, sarcopenia, and inactivity
Evans, W. J. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.28608a · Cited by 724 · see citing works
Skeletal muscle: A review of molecular structure and function, in health and disease
Mukund, K., & Subramaniam, S. (2019) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1462 · Cited by 680 · see citing works
Antibacterial activity of flavonoids and their structure–activity relationship: An update review
Farhadi, F., Khameneh, B., Iranshahi, M., & Iranshahy, M. (2018) · Phytotherapy Research · doi:10.1002/ptr.6208 · Cited by 639 · see citing works
Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials
Marzetti, E., Calvani, R., Cesari, M., Buford, T. W., Lorenzi, M., Behnke, B. J., & Leeuwenburgh, C. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.06.024 · Cited by 627 · see citing works
Anti-inflammatory activity of natural dietary flavonoids
Pan, M., Lai, C., & Ho, C. (2010) · Food & Function · doi:10.1039/c0fo00103a · Cited by 612 · see citing works
Cancer preventive effects of flavonoids—a review
Marchand, L. L. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00186-5 · Cited by 583 · see citing works
Signaling pathways controlling skeletal muscle mass
Egerman, M. A., & Glass, D. J. (2014) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2013.857291 · Cited by 555 · see citing works
Molecular Mechanisms of the Anti-Obesity and Anti-Diabetic Properties of Flavonoids
Kawser Hossain, M., Abdal Dayem, A., Han, J., Yin, Y., Kim, K., Kumar Saha, S., Yang, G.-M., Choi, H., & Cho, S.-G. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17040569 · Cited by 495 · see citing works
Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance
Davis, J. M., Murphy, E. A., Carmichael, M. D., & Davis, B. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90925.2008 · Cited by 486 · see citing works
Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats
Rivera, L., Morón, R., Sánchez, M., Zarzuelo, A., & Galisteo, M. (2008) · Obesity · doi:10.1038/oby.2008.315 · Cited by 473 · see citing works
Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways
Rodriguez, J., Vernus, B., Chelh, I., Cassar-Malek, I., Gabillard, J. C., Hadj Sassi, A., Seiliez, I., Picard, B., & Bonnieu, A. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1689-x · Cited by 397 · see citing works
Flavonoids: modulators of brain function?
Spencer, J. P. E. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508965776 · Cited by 385 · see citing works
Molecular and cellular mechanisms of skeletal muscle atrophy: an update
Fanzani, A., Conraads, V. M., Penna, F., & Martinet, W. (2012) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-012-0074-6 · Cited by 372 · see citing works
Skeletal Muscle Mitochondria and Aging: A Review
Peterson, C. M., Johannsen, D. L., & Ravussin, É. (2012) · Journal of Aging Research · doi:10.1155/2012/194821 · Cited by 318 · see citing works
Akowuah, G. A., Ismail, Z., Norhayati, I., & Sadikun, A. (2004) · Food Chemistry · doi:10.1016/j.foodchem.2004.09.028 · Cited by 301 · see citing works
Tizioto, P. C., Coutinho, L. L., de Oliveira, P. S. N., César, A. S. M., Diniz, W. J. S., de Lima, A. O., Rocha, M. I. P., Decker, J. E., Schnabel, R. D., Mourão, G. B., et al. (2017) · Scientific Reports · doi:10.1038/srep44345 · Cited by 291 · see citing works
The Endocrine Activities of 8-Prenylnaringenin and Related Hop (Humulus lupulus L.) Flavonoids
Milligan, S. R., Kalita, J. C., Pocock, V., Kauter, V. V. D., Stevens, J. F., Deinzer, M. L., Rong, H., & Keukeleire, D. D. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.12.7168 · Cited by 231 · see citing works
Molecular mechanisms of anti-inflammatory activity mediated by flavonoids
Gomes, A., Fernandes, E., Lima, J., Mira, L., & Corvo, M. (2008) · Current Medicinal Chemistry · doi:10.2174/092986708784911579 · Cited by 227 · see citing works
Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease
Feige, P., Brun, C. E., Ritso, M., & Rudnicki, M. A. (2018) · Cell stem cell · doi:10.1016/j.stem.2018.10.006 · Cited by 227 · see citing works
Seo, M.-J., Lee, Y., Hwang, J., Kim, K., & Lee, B.-Y. (2015) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2015.06.005 · Cited by 217 · see citing works
Self-citationvan Dam, R. M., Naidoo, N., & Landberg, R. (2013) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e32835bcdff · Cited by 212 · see citing works
Redox control of skeletal muscle atrophy.
Powers, S. K., Morton, A. B., Ahn, B., & Smuder, A. J. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.02.021 · Cited by 207 · see citing works
(–)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle
Nogueira, L., Ramirez‐Sanchez, I., Perkins, G. A., Murphy, A., Taub, P. R., Ceballos, G., Villarreal, F. J., Hogan, M. C., & Malek, M. H. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.209924 · Cited by 205 · see citing works
Chen, L., Teng, H., Jia, Z., Battino, M. A., Miron, A., Yu, Z., Cao, H., & Xiao, J. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1345853 · Cited by 205 · see citing works
Fan, J., Yang, X., Li, J., Shu, Z., Dai, J., Liu, X., Li, B., Jia, S., Kou, X., Yang, Y., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.15728 · Cited by 179 · see citing works
Wang, D., Yin, Y., Yang, Y., Lv, P.-J., Shi, Y. Q., Lu, L., & Wei, L.-B. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.02.002 · Cited by 176 · see citing works
Cytokine Signaling in Skeletal Muscle Wasting
Zhou, J., Liu, B., Liang, C., Li, Y., & Song, Y.-H. (2016) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2016.03.002 · Cited by 172 · see citing works
Dietary Protein to Support Anabolism with Resistance Exercise in Young Men
Phillips, S. M., Hartman, J. W., & Wilkinson, S. B. (2005) · Journal of the American College of Nutrition · doi:10.1080/07315724.2005.10719454 · Cited by 169 · see citing works
Quercetin Protects against Obesity-Induced Skeletal Muscle Inflammation and Atrophy
Le, N. H., Kim, C.-S., Park, T., Park, J. H. Y., Sung, M.-K., Lee, D. G., Hong, S.-M., Choe, S.-Y., Goto, T., Kawada, T., et al. (2014) · Mediators of Inflammation · doi:10.1155/2014/834294 · Cited by 167 · see citing works
Self-citationBiochemical Pathways of Sarcopenia and Their Modulation by Physical Exercise: A Narrative Review
Ziaaldini, M. M., Marzetti, E., Picca, A., & Murlasits, Z. (2017) · Frontiers in Medicine · doi:10.3389/fmed.2017.00167 · Cited by 167 · see citing works
Molecular mechanism of sarcopenia and cachexia: recent research advances
Sakuma, K., Aoi, W., & Yamaguchi, A. (2017) · Pflügers Archiv: European Journal of Physiology · doi:10.1007/s00424-016-1933-3 · Cited by 144 · see citing works
Silibinin and STAT3: A natural way of targeting transcription factors for cancer therapy
Bosch‐Barrera, J., & Menéndez, J. A. (2015) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2015.04.008 · Cited by 139 · see citing works
Mtor is necessary for proper satellite cell activity and skeletal muscle regeneration
Zhang, P., Liang, X., Shan, T., Jiang, Q., Deng, C., Zheng, R., & Kuang, S. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.05.032 · Cited by 133 · see citing works
Roles of mTOR Signaling in Tissue Regeneration
Wei, X., Luo, L., & Chen, J.-Z. (2019) · Cells · doi:10.3390/cells8091075 · Cited by 132 · see citing works
MUSCLE DISUSE AS A PIVOTAL PROBLEM IN SARCOPENIA-RELATED MUSCLE LOSS AND DYSFUNCTION
Bell, K. E., von Allmen, M., Devries, M. C., & Phillips, S. M. (2016) · The Journal of Frailty & Aging · doi:10.14283/jfa.2016.78 · Cited by 127 · see citing works
Wei, Y., Zhang, J., Zhou, Y., Bei, W., Li, Y., Yuan, Q., & Liang, H. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.11.093 · Cited by 125 · see citing works
Protective roles of flavonoids and flavonoid-rich plant extracts against urolithiasis: A review
Zeng, X., Xi, Y., & Jiang, W. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1439880 · Cited by 125 · see citing works
Effects of (−)-epicatechin on molecular modulators of skeletal muscle growth and differentiation
Gutiérrez-Salmeán, G., Ciaraldi, T. P., Nogueira, L., Barboza, J., Taub, P. R., Hogan, M. C., Henry, R. R., Meaney, E., Villarreal, F. J., Ceballos, G. M., et al. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.09.007 · Cited by 113 · see citing works
Bioenergetic provision of energy for muscular activity
Wells, G. D., Selvadurai, H., & Tein, I. (2009) · Paediatric Respiratory Reviews · doi:10.1016/j.prrv.2009.04.005 · Cited by 103 · see citing works
Shukla, S. K., Dasgupta, A., Mehla, K., Gunda, V., Vernucci, E., Souchek, J., Goode, G., King, R., Mishra, A., Rai, I., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.5843 · Cited by 96 · see citing works
Moreno‐Ulloa, A., Nogueira, L., Rodríguez, A., Barboza, J., Hogan, M. C., Ceballos, G. M., Villarreal, F. J., & Ramírez‐Sánchez, I. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu131 · Cited by 94 · see citing works
The Effects of Flavonoids on Bone
Welch, A. A., & Hardcastle, A. C. (2014) · Current Osteoporosis Reports · doi:10.1007/s11914-014-0212-5 · Cited by 91 · see citing works
Coldham, N. G., & Sauer, M. J. (2001) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(01)00081-3 · Cited by 88 · see citing works
Mitochondrial dysregulation and muscle disuse atrophy
Ji, L. L., & Yeo, D. (2019) · F1000Research · doi:10.12688/f1000research.19139.1 · Cited by 86 · see citing works
Prevention of Disuse Muscle Atrophy by Dietary Ingestion of 8-Prenylnaringenin in Denervated Mice
Mukai, R., Horikawa, H., Fujikura, Y., Kawamura, T., Nemoto, H., Nikawa, T., & Terao, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0045048 · Cited by 83 · see citing works
Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia
Wang, H., Lai, Y.-J., Chan, Y.-L., Li, T., & Wu, C. (2011) · Cancer Letters · doi:10.1016/j.canlet.2011.02.023 · Cited by 83 · see citing works
Polyphenols and Their Potential Role in Preventing Skeletal Muscle Atrophy
Salucci, S., & Falcieri, E. (2020) · Nutrition Research · doi:10.1016/j.nutres.2019.11.004 · Cited by 83 · see citing works
Kou, X., Li, J., Liu, X., Yang, X., Fan, J., & Chen, N. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.03.070 · Cited by 81 · see citing works
Choi, W. H., Son, H. J., Jang, Y. J., Ahn, J., Jung, C. H., & Ha, T. Y. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700218 · Cited by 81 · see citing works
The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice
Caron, A. Z., Haroun, S., Leblanc, É., Trensz, F., Guindi, C., Amrani, A., & Grenier, G. (2011) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-12-185 · Cited by 80 · see citing works
Kim, C., & Hwang, J.-K. (2020) · Nutrients · doi:10.3390/nu12041079 · Cited by 80 · see citing works
Self-citationMukai, R., Matsui, N., Fujikura, Y., Matsumoto, N., Hou, D., Kanzaki, N., Shibata, H., Horikawa, M., Iwasa, K., Hirasaka, K., et al. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.02.001 · Cited by 75 · see citing works
The roles of muscle stem cells in muscle injury, atrophy and hypertrophy
Fukada, S. (2018) · The Journal of Biochemistry · doi:10.1093/jb/mvy019 · Cited by 74 · see citing works
Quercetin supplementation attenuates the progression of cancer cachexia in ApcMin/+ mice.
Velázquez, K. T., Enos, R. T., Narsale, A. A., Puppa, M. J., Davis, J., Murphy, E., & Carson, J. (2014) · Journal of NutriLife · doi:10.3945/jn.113.188367 · Cited by 71 · see citing works
Liu, H., Chan, Y., Wang, M.-F., Wei, C.-C., & Chang, S.-J. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b02501 · Cited by 70 · see citing works
Meador, B. M., Mirza, K. A., Tian, M., Skelding, M. B., Reaves, L. A., Edens, N. K., Tisdale, M. J., & Pereira, S. L. (2015) · The Journal of Frailty & Aging · doi:10.14283/jfa.2015.58 · Cited by 69 · see citing works
Kim, Y., Kim, C.-S., Joe, Y., Chung, H. T., Ha, T. Y., & Yu, R. (2018) · Journal of Medicinal Food · doi:10.1089/jmf.2017.4108 · Cited by 69 · see citing works
Self-citationCatechins enhance skeletal muscle performance
Li, P., Liu, A., Xiong, W., Lin, H., Xiao, W., Huang, J., Zhang, S., & Liu, Z. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1549534 · Cited by 67 · see citing works
Mukai, R., Nakao, R., Yamamoto, H., Nikawa, T., Takeda, E., & Terao, J. (2010) · Journal of Natural Products · doi:10.1021/np100240y · Cited by 66 · see citing works
Toda, K., Hitoe, S., Takeda, S., & Shimoda, H. (2016) · Heliyon · doi:10.1016/j.heliyon.2016.e00115 · Cited by 64 · see citing works
Huang, Y., Chen, K., Ren, Q., Yi, L., Zhu, J., Zhang, Q., & Mi, M. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000493040 · Cited by 64 · cited 7× · see citing works
“Besides apoptosis, the overexpression of ROS decreases the production of ATP by suppressing mitochondrial respiratory chain complexes; therefore, reducing oxidative stress has been suggested as a strategy to prevent muscle atrophy (Huang et al., 2018).”
BackgroundInfluentialMoreno‐Ulloa, A., Miranda‐Cervantes, A., Licea-Navarro, A. F., Mansour, C. M., Beltrán‐Partida, E., Donis‐Maturano, L., la Herrán, H. C. D.-D., Villarreal, F. J., & Álvarez‐Delgado, C. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.01.014 · Cited by 63 · see citing works
Epigallocatechin-3-gallate improves plantaris muscle recovery after disuse in aged rats
Alway, S. E., Bennett, B., Wilson, J. C., Edens, N. K., & Pereira, S. L. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.11.011 · Cited by 60 · see citing works
Hirasaka, K., Maeda, T., Ikeda, C., HARUNA, M., Kohno, S., Abe, T., Ochi, A., Mukai, R., Oarada, M., Kondo, S., et al. (2013) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.59.317 · Cited by 59 · see citing works
Apigenin Enhances Skeletal Muscle Hypertrophy and Myoblast Differentiation by Regulating Prmt7
Jang, Y. J., Son, H. J., Choi, Y. M., Ahn, J., Jung, C. H., & Ha, T. Y. (2017) · Oncotarget · doi:10.18632/oncotarget.20962 · Cited by 59 · see citing works
Liu, J., & Lou, Y. (2004) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2004.06.021 · Cited by 56 · see citing works
Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes
Hemdan, D. I. I., Hirasaka, K., Nakao, R., Kohno, S., Kagawa, S., Abe, T., Harada‐Sukeno, A., Okumura, Y., Nakaya, Y., Terao, J., et al. (2009) · The Journal of Medical Investigation · doi:10.2152/jmi.56.26 · Cited by 56 · see citing works
Attenuation of muscle wasting in murine C 2 C 12 myotubes by epigallocatechin‐3‐gallate
Mirza, K. A., Pereira, S. L., Edens, N. K., & Tisdale, M. J. (2014) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-014-0139-9 · Cited by 55 · see citing works
Dietary epicatechin improves survival and delays skeletal muscle degeneration in aged mice
Si, H., Wang, X., Zhang, L., Parnell, L. D., Ahmed, B., LeRoith, T., Ansah, T.-A., Zhang, L., Li, J., Ordovás, J. M., et al. (2018) · The FASEB Journal · doi:10.1096/fj.201800554rr · Cited by 54 · see citing works
Quercetin glycosides prevent dexamethasone-induced muscle atrophy in mice
Otsuka, Y., Egawa, K., Kanzaki, N., Izumo, T., Rogi, T., & Shibata, H. (2019) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2019.100618 · Cited by 54 · see citing works
Glabridin Inhibits Dexamethasone-Induced Muscle Atrophy
Yoshioka, Y., Kubota, Y., Samukawa, Y., Yamashita, Y., & Ashida, H. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.02.006 · Cited by 54 · see citing works
Kauntz, H., Bousserouel, S., Gossé, F., & Raul, F. (2012) · APOPTOSIS · doi:10.1007/s10495-012-0731-4 · Cited by 52 · see citing works
Chang, Y., Chen, Y.-T., Liu, H., Chan, Y., Liu, M., Hu, S., Tseng, W., Wu, H., Wang, M., & Chang, S. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801102 · Cited by 52 · see citing works
Chen, M., Qin, J., Chen, S.-J., Yao, L., Zhang, L., Yin, Z., & Liao, H. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.04.006 · Cited by 51 · see citing works
Kim, D., Lee, M.-S., Jo, K.-S., Lee, K.-E., & Hwang, J.-M. (2011) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2011.01379.x · Cited by 49 · see citing works
Self-citationLong-term quercetin dietary enrichment decreases muscle injury in mdx mice
Hollinger, K., Shanely, R. A., Quindry, J. C., & Selsby, J. T. (2014) · Clinical Nutrition · doi:10.1016/j.clnu.2014.06.008 · Cited by 49 · see citing works
Catechins Activate Muscle Stem Cells by Myf5 Induction and Stimulate Muscle Regeneration
Kim, A. R., Kim, K. M., Byun, M. R., Hwang, J.-H., Park, J. I., Oh, H. T., Kim, H. K., Jeong, M. G., Hwang, E. S., & Hong, J.-H. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.05.114 · Cited by 49 · see citing works
Self-citationMolecular mechanisms and therapeutic interventions in sarcopenia
Park, S. S., Kwon, E., & Kwon, K. (2017) · Osteoporosis and Sarcopenia · doi:10.1016/j.afos.2017.08.098 · Cited by 49 · see citing works
Delphinidin Prevents Muscle Atrophy and Upregulates miR-23a Expression
Murata, M., Nonaka, H., Komatsu, S., Goto, M., Morozumi, M., Yamada, S., Lin, I.-C., Yamashita, S., & Tachibana, H. (2017) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6b03661 · Cited by 47 · see citing works
Flavones Inhibit LPS-Induced Atrogin-1/MAFbx Expression in Mouse C2C12 Skeletal Myotubes
SHIOTA, C., ABE, T., KAWAI, N., OHNO, A., TESHIMA-KONDO, S., MORI, H., TERAO, J., TANAKA, E., & NIKAWA, T. (2015) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.61.188 · Cited by 46 · see citing works
Toda, K., Takeda, S., Hitoe, S., Nakamura, S., Matsuda, H., & Shimoda, H. (2015) · Journal of Natural Medicines · doi:10.1007/s11418-015-0948-y · Cited by 46 · see citing works
Zhang, Z., Li, J., Jin, L. I. U., Guo, B., Leung, A. C., Zhang, G., & Zhang, B. (2016) · Scientific Reports · doi:10.1038/srep20300 · Cited by 46 · see citing works
Yoshino, M., Naka, A., Sakamoto, Y. S., Shibasaki, A., Toh, M., Tsukamoto, S., Kondo, K. N., & Iida, K. (2015) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2015.05.010 · Cited by 45 · see citing works
Ma, J., Kang, S. Y., Meng, X., Kang, A. N., Park, J. H., Park, Y., & Jung, H. W. (2018) · Molecules · doi:10.3390/molecules23082023 · Cited by 44 · see citing works
Molecular mechanisms relating to amino acid regulation of protein synthesis
Cao, Y.-C., Liu, S.-M., Liu, K., Abbasi, I., Cai, C., & Yao, J.-H. (2019) · Nutrition research reviews · doi:10.1017/s0954422419000052 · Cited by 43 · see citing works
Ogawa, M., Kitano, T., 夏初, 河., Sugihira, T., Kitakaze, T., Harada, N., & Yamaji, R. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.07.017 · Cited by 41 · see citing works
Targeting Mitochondrial Biogenesis to Treat Insulin Resistance
Zamora, M., & Villena, J. A. (2014) · Current Pharmaceutical Design · doi:10.2174/1381612820666140306102514 · Cited by 39 · see citing works
Characterization of Orange Juice (Citrus sinensis) by Polymethoxylated Flavones
Ooghe, W. C., Ooghe, S. J., Detavernier, C. M., & Huyghebaert, A. D. (1994) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00046a021 · Cited by 39 · see citing works
Yang, J., Cao, J., Tian, L., & Liu, F. (2011) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-011-1686-9 · Cited by 39 · see citing works
Licorice flavonoid oil enhances muscle mass in KK-A mice
Yoshioka, Y., Yamashita, Y., Kishida, H., Nakagawa, K., & Ashida, H. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.05.024 · Cited by 39 · see citing works
Kweon, M., Lee, H., Park, C., Choi, Y. H., & Ryu, J. (2019) · Nutrients · doi:10.3390/nu11102419 · Cited by 39 · see citing works
Takahashi, H., Suzuki, Y., Mohamed, J. S., Gotoh, T., Pereira, S. L., & Alway, S. E. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.02.075 · Cited by 36 · see citing works
Epicatechin elicits MyoD-dependent myoblast differentiation and myogenic conversion of fibroblasts
Lee, S.-J., Leem, Y.-E., Go, G.-Y., Choi, Y., Song, Y. J., Kim, I., Kim, D. Y., Kim, Y. K., Seo, D. W., Kang, J., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175271 · Cited by 35 · see citing works
Chen, T., Li, B., Xu, Y., Meng, S., Wang, Y., & Jiang, Y. (2018) · Oncology Reports · doi:10.3892/or.2018.6453 · Cited by 35 · see citing works
Corylifol A from Psoralea corylifolia L. Enhances Myogenesis and Alleviates Muscle Atrophy
Han, Y., Lee, H., Li, H., & Ryu, J.-H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051571 · Cited by 34 · see citing works
Messina, S., Bitto, A., Aguennouz, M., Vita, G. L., Polito, F., Irrera, N., Altavilla, D., Marini, H., Migliorato, A., Squadrito, F., et al. (2011) · Neuromuscular Disorders · doi:10.1016/j.nmd.2011.04.014 · Cited by 33 · see citing works
Song, Y., Kim, M., Kim, C., Kim, J., & Hwang, J. (2016) · Journal of Medicinal Food · doi:10.1089/jmf.2016.3800 · Cited by 33 · see citing works
Self-citationRole and mechanism of catechin in skeletal muscle cell differentiation
Li, P., Liu, A., Liu, C., Qu, Z., Xiao, W., Huang, J., Liu, Z., & Zhang, S. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108225 · Cited by 31 · see citing works
Long-Term Quercetin Dietary Enrichment Partially Protects Dystrophic Skeletal Muscle
Spaulding, H. R., Ballmann, C. G., Quindry, J. C., & Selsby, J. T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168293 · Cited by 30 · see citing works
Ballmann, C. G., Hollinger, K., Selsby, J. T., Amin, R., & Quindry, J. C. (2014) · Experimental Physiology · doi:10.1113/expphysiol.2014.083360 · Cited by 29 · see citing works
Apigenin inhibits sciatic nerve denervation–induced muscle atrophy
Choi, W. H., Jang, Y. J., Son, H. J., Ahn, J., Jung, C. H., & Ha, T. Y. (2018) · Muscle & Nerve · doi:10.1002/mus.26133 · Cited by 29 · see citing works
Red Bean Extract Inhibits Immobilization-Induced Muscle Atrophy in C57BL/6N Mice
Kim, C., Kim, M., & Hwang, J. (2019) · Journal of Medicinal Food · doi:10.1089/jmf.2019.4426 · Cited by 29 · see citing works
Self-citationLi, B., Wan, L., Li, Y., Yu, Q., Chen, P., Gan, R., Yang, Q., Han, Y., & Guo, C. (2014) · Tumor Biology · doi:10.1007/s13277-014-2558-9 · Cited by 28 · see citing works
Renno, W. M., Al‐Maghrebi, M., & Al-Banaw, A. G. (2012) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-012-0758-7 · Cited by 27 · see citing works
Pellegrini, M., Bulzomi, P., Galluzzo, P., Lecis, M., Leone, S., Pallottini, V., & Marino, M. (2014) · Genes & Nutrition · doi:10.1007/s12263-014-0425-3 · Cited by 26 · see citing works
Chan, S.-T., Chuang, C., Lin, Y., Liao, J., Lii, C., & Yeh, S.-L. (2017) · Food & Function · doi:10.1039/c7fo01444a · Cited by 26 · see citing works
Lee, S., Kim, C., Kwon, D., Kim, M., & Hwang, J. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/8161042 · Cited by 26 · see citing works
Self-citationOral quercetin administration transiently protects respiratory function in dystrophin‐deficient mice
Selsby, J. T., Ballmann, C. G., Spaulding, H. R., Ross, J. W., & Quindry, J. C. (2016) · The Journal of Physiology · doi:10.1113/jp272057 · Cited by 25 · see citing works
In Vitro Effects of Soy Phytoestrogens on Rat L6 Skeletal Muscle Cells
Jones, K. L., Harty, J. R., Roeder, M. J., Winters, T. A., & Banz, W. J. (2005) · Journal of Medicinal Food · doi:10.1089/jmf.2005.8.327 · Cited by 24 · see citing works
(-)-Epigallocatechin-3-gallate stimulates myogenic differentiation through TAZ activation
Kim, A. R., Kim, K. M., Byun, M. R., Hwang, J.-H., Park, J. I., Oh, H. T., Jeong, M. G., Hwang, E. S., & Hong, J.-H. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.03.049 · Cited by 24 · see citing works
Self-citationAoyama, S., Jia, H., Nakazawa, K., Yamamura, J., Saito, K., & Kato, H. (2016) · The Journal of Nutrition · doi:10.3945/jn.115.226316 · Cited by 23 · see citing works
Anabolic Activity of a Soy Extract and Three Major Isoflavones in C2C12 Myotubes
Zheng, W., Hemker, M., Xie, M., Soukup, S., & Diel, P. (2018) · Planta Medica · doi:10.1055/a-0598-4812 · Cited by 23 · see citing works
Kim, S.-H., Hong, S. H., Park, Y., Sung, J.-H., Suh, W., Lee, K. W., Jung, K., Lim, C., Kim, J.-H., Kim, H., et al. (2019) · Scientific Reports · doi:10.1038/s41598-018-38281-0 · Cited by 23 · see citing works
Mukai, R., Horikawa, H., Lin, P.-Y., Tsukumo, N., Nikawa, T., Kawamura, T., Nemoto, H., & Terao, J. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00521.2015 · Cited by 21 · see citing works
Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells
Kim, J., Kim, S. M., Ha, S. E., Vetrivel, P., Saralamma, V. V. G., Kim, E. H., & Kim, G. S. (2019) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-019-2714-2 · Cited by 21 · see citing works
Chang, W.-T., Chen, C.-S., Cheng, M., Wu, M., Cheng, F., & Hsu, C. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.06.020 · Cited by 20 · see citing works
Sa, B.-K., Kim, C., Kim, M., & Hwang, J. (2017) · Journal of Medicinal Food · doi:10.1089/jmf.2017.3970 · Cited by 20 · see citing works
Self-citationKim, H., Kim, C., Kook, K. E., Yanti, Y., Choi, S., Kang, W., & Hwang, J. (2018) · Journal of Medicinal Food · doi:10.1089/jmf.2017.4155 · Cited by 20 · see citing works
Self-citationYoshimura, T., Saitoh, K., Sun, L., Wang, Y., Taniyama, S., Yamaguchi, K., Uchida, T., Ohkubo, T., Higashitani, A., Nikawa, T., et al. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.10.184 · Cited by 20 · see citing works
Natural constituents from food sources: potential therapeutic agents against muscle wasting
Shen, S., Yu, H., Gan, L., Yang, Y., & Lin, L. (2019) · Food & Function · doi:10.1039/c9fo00912d · Cited by 20 · see citing works
Flavonoids: A Nutritional Protection Against Oxidative and UV Induced Cellular Damages
Saraf, S., Ashawat, M. S., & Saraf, S. (2007) · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review · Cited by 19 · see citing works
Delphinidin Prevents Disuse Muscle Atrophy and Reduces Stress-Related Gene Expression
Murata, M., Kosaka, R., Kurihara, K., Yamashita, S., & Tachibana, H. (2016) · Bioscience Biotechnology and Biochemistry · doi:10.1080/09168451.2016.1184560 · Cited by 19 · see citing works
Ding, W., Chen, X., Li, W. J., Fu, Z. F., & Shi, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-03484-4 · Cited by 19 · see citing works
An isoflavone compound daidzein elicits myoblast differentiation and myotube growth
Lee, S.-J., Vuong, T. A., Go, G.-Y., Song, Y.-J., Lee, S., Lee, S.-Y., Kim, S.-W., Lee, J., Kim, Y. K., Seo, D. W., et al. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.09.016 · Cited by 19 · see citing works
Luteolin Attenuates Dexamethasone-Induced Skeletal Muscle Atrophy in Male Albino Rats
HAWILA, M. S. S. H. N., & ELMAABOUD, M. D. A. A. M. (2019) · The Medical Journal of Cairo University/The Medical Journal of Cairo University · doi:10.21608/mjcu.2019.65632 · Cited by 19 · see citing works
Li, H., Zhang, X., & Wang, W. (2017) · African Journal of Traditional Complementary and Alternative Medicines · doi:10.21010/ajtcam.v14i4.24 · Cited by 17 · see citing works
Hur, J., Kim, M. K., Choi, S. Y., Jang, Y. J., & Ha, T. Y. (2018) · Phytotherapy Research · doi:10.1002/ptr.6235 · Cited by 16 · see citing works
Lückemann, L., Unteroberdörster, M., Gomez, E. M., Schedlowski, M., & Hadamitzky, M. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.04.013 · Cited by 16 · see citing works
Kim, T., Kim, M., Kim, C., Jung, H., & Hwang, J. (2016) · Journal of Medicinal Food · doi:10.1089/jmf.2015.3630 · Cited by 12 · see citing works
Self-citationEffect ofOenothera odorataRoot Extract on Microgravity and Disuse-Induced Muscle Atrophy
Lee, Y.-H., Seo, D.-H., Park, J., Kabayama, K., Opitz, J. L., Lee, K. H., Kim, H. S., & Kim, T. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/130513 · Cited by 11 · see citing works
Role of dietary flavonoids in oxidative stress and prevention of muscle atrophy
Mukai, R., & Terao, J. (2013) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.2.385 · Cited by 11 · see citing works
Hong, K.-B., Lee, H.-S., Kim, D. H., Moon, J. M., & Park, Y. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/4319398 · Cited by 10 · see citing works
Rong, Y., Wu, J., Liu, X., Zhao, B., & Wang, Z. (2014) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2014.02.013 · Cited by 7 · see citing works
Emanuele, E., Bertona, M., Pareja-Galeano, H., Fiuza‐Luces, C., Morales, J. S., Sanchis‐Gomar, F., & Lucía, A. (2016) · PubMed · Cited by 5 · see citing works
Anti-inflammatory activities of sinensetin on LPS-stimulated L6 skeletal muscle cells
Kim, J., Ha, S. E., Kim, S. M., Vetrivel, P., Kim, G. S., & Kim, E. H. (2019) · Journal of Biomedical Translational Research · doi:10.12729/jbtr.2019.20.1.001 · Cited by 5 · see citing works
Zong-kang, Zhang, Jie, J., Li, Wing-nang, Leung, Ge, G., & Bao-ting (2015) · 中国药理学与毒理学杂志 · Cited by 4 · see citing works
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Păcularu‐Burada, B., Cîrîc, A., & Begea, M. (2024) · Foods · doi:10.3390/foods13152441 · Cited by 78 · see citing works
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Simone, G. D., Balducci, C., Forloni, G., Pastorelli, R., & Brunelli, L. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101466 · Cited by 65 · see citing works
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Wang, Y., Liu, Q., Quan, H., Kang, S.-G., Huang, K., & Tong, T. (2021) · Nutrients · doi:10.3390/nu13061914 · Cited by 61 · see citing works
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Kumar, P., Yadav, N., Chaudhary, B., Jain, V., Balaramnavar, V. M., Alharbi, K. S., Alenezi, S. K., Almalki, W. H., Ghoneim, M. M., Alshehri, S., et al. (2021) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2021.109745 · Cited by 43 · see citing works
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Jung, U. J. (2023) · Antioxidants · doi:10.3390/antiox12051063 · Cited by 41 · see citing works
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Николаевна, П. Е., Koval, L. A., Platonova, E. Y., Golubev, D., Ulyasheva, N. S., Babak, T. V., Shaposhnikov, M. V., & Moskalev, A. (2024) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0247 · Cited by 34 · see citing works
González‐Hedström, D., Priego, T., Amor, S., de la Fuente‐Fernández, M., Martı́n, A. I., López‐Calderón, A., Inarejos-García, A. M., Garcı́a-Villalón, Á. L., & Granado, M. (2021) · Antioxidants · doi:10.3390/antiox10050737 · Cited by 31 · see citing works
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Medoro, A., Scapagnini, G., & Davinelli, S. (2024) · The Journal of Frailty & Aging · doi:10.14283/jfa.2024.73 · Cited by 26 · see citing works
Edwards, S. J., Carter, S., Nicholson, T., Allen, S., Morgan, P. T., Jones, S. W., Rendeiro, C., & Breen, L. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109150 · Cited by 18 · see citing works
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Hour, T., Nhi, N. T. L., Lai, I., Chuu, C., Lin, P., Chang, H., Su, Y., Chen, C., & Chen, Y. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300685 · Cited by 16 · see citing works
Prajapati, P., Kumar, A., Chaudary, R., Mangrulkar, S. V., Arya, M., & Kushwaha, S. (2023) · Current Molecular Pharmacology · doi:10.2174/1874467216666230308142137 · Cited by 17 · see citing works
Jhuo, C., Hsieh, S., Chen, W., & Tzen, J. T. C. (2023) · Molecules · doi:10.3390/molecules28020688 · Cited by 15 · see citing works
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Ding, K., Jiang, W., Zhangwang, J., Wang, Y., Zhang, J., & Lei, M. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02639-7 · Cited by 11 · see citing works
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- Authors
- Kim, C., & Hwang, J.-K.
- Affiliations
- Yonsei University (KR)
- Corresponding author
- Hwang, Jae-Kwan
- Venue
- Food Science and Biotechnology
- Published
- 2020-09-16
- Volume
- 29
- Issue
- 12
- Pages
- 1619-1640
- ISSN
- 1226-7708 (ISSN-L)
- 2092-6456
- PMC
- PMC7708614
- OpenAlex
- W3091973957
- Cited by
- 45
- References
- 144
- Citations by year
- 2026: 11 · 2025: 3 · 2024: 13 · 2023: 9 · 2022: 4 · 2021: 5
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Update notices
- correction (2020-11-20)
- Open access
- hybrid
- doi.org
- Locations
- Food Science and Biotechnology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Ministry of Agriculture, Food and Rural Affairs (320011-02)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- flavonoids, muscle atrophy, sarcopenia, cachexia, disuse atrophy, nutraceuticals, polyphenols, protein turnover, mitochondrial activity, myogenesis, anti-inflammatory activity, anti-oxidation, plant extracts
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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