Factors influencing the gut microbiome in children: from infancy to childhood

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

Nishita, M., Park, S.-Y., Nishio, T., Kamizaki, K., Wang, Z., Tamada, K., Takumi, T., Hashimoto, R., Otani, H., Pazour, G. J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-016-0028-x · Cited by 15,947

Diet rapidly and reproducibly alters the human gut microbiome

David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., et al. (2014) · Nature · doi:10.1038/nature12820 · Cited by 10,100

A core gut microbiome in obese and lean twins

Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., Sogin, M. L., Jones, W. J., Roe, B. A., Affourtit, J. P., et al. (2009) · Nature · doi:10.1038/nature07540 · Cited by 7,823

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005963107 · Cited by 5,579

Hay fever, hygiene, and household size.

Strachan, D. P. (1989) · BMJ · doi:10.1136/bmj.299.6710.1259 · Cited by 5,054

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

Dominguez-Bello, M. G., Costello, E. K., Contreras, M., Magris, M., Hidalgo, G., Fierer, N., & Knight, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002601107 · Cited by 4,774

Functional interactions between the gut microbiota and host metabolism

Tremaroli, V., & Bäckhed, F. (2012) · Nature · doi:10.1038/nature11552 · Cited by 4,387

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., et al. (2015) · Cell Host & Microbe · doi:10.1016/j.chom.2015.04.004 · Cited by 3,315

Human Genetics Shape the Gut Microbiome

Goodrich, J. K., Waters, J. L., Poole, A. C., Sutter, J. L., Koren, O., Blekhman, R., Beaumont, M., Van Treuren, W., Knight, R., Bell, J. T., et al. (2014) · Cell · doi:10.1016/j.cell.2014.09.053 · Cited by 3,164

Atopic Dermatitis: Global Epidemiology and Risk Factors

Nutten, S. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000370220 · Cited by 3,124

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

Turnbaugh, P. J., Ridaura, V. K., Faith, J. J., Rey, F. E., Knight, R., & Gordon, J. I. (2009) · Science Translational Medicine · doi:10.1126/scitranslmed.3000322 · Cited by 3,058 · cited 2×

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

Morgan, X. C., Tickle, T. L., Sokol, H., Gevers, D., Devaney, K. L., Ward, D. V., Reyes, J. A., Shah, S. A., LeLeiko, N., Snapper, S. B., et al. (2012) · Genome Biology · doi:10.1186/gb-2012-13-9-r79 · Cited by 2,713

Succession of microbial consortia in the developing infant gut microbiome

Koenig, J. E., Spor, A., Scalfone, N., Fricker, A. D., Stombaugh, J., Knight, R., Angenent, L. T., & Ley, R. E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000081107 · Cited by 2,540

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

Dethlefsen, L., & Relman, D. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000087107 · Cited by 2,421

Factors influencing the composition of the intestinal microbiota in early infancy

Penders, J., Thijs, C., Vink, C., Stelma, F. F., Snijders, B., Kummeling, I., van den Brandt, P. A., & Stobberingh, E. E. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2824 · Cited by 2,232

Temporal development of the gut microbiome in early childhood from the TEDDY study

Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H., Metcalf, G., et al. (2018) · Nature · doi:10.1038/s41586-018-0617-x · Cited by 2,055

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

Schwandner, R., Dziarski, R., Wesche, H., Rothe, M., & Kirschning, C. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17406 · Cited by 1,704

High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome

De Filippis, F., Pellegrini, N., Vannini, L., Jeffery, I. B., La Storia, A., Laghi, L., Serrazanetti, D. I., Di Cagno, R., Ferrocino, I., Lazzi, C., et al. (2016) · Gut · doi:10.1136/gutjnl-2015-309957 · Cited by 1,638

Antibiotics in early life alter the murine colonic microbiome and adiposity

Cho, I., Yamanishi, S., Cox, L., Methé, B. A., Zavadil, J., Li, K., Gao, Z., Mahana, D., Raju, K., Teitler, I., et al. (2012) · Nature · doi:10.1038/nature11400 · Cited by 1,613

Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study

Odamaki, T., Kato, K., Sugahara, H., Hashikura, N., Takahashi, S., Xiao, J.-Z., Abe, F., & Osawa, R. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0708-5 · Cited by 1,521

Association between Bacterial Vaginosis and Preterm Delivery of a Low-Birth-Weight Infant

Hillier, S. L., Nugent, R. P., Eschenbach, D. A., Krohn, M. A., Gibbs, R. S., Martin, D. H., Cotch, M. F., Edelman, R., Pastorek, J. G., Rao, A. V., et al. (1995) · New England Journal of Medicine · doi:10.1056/nejm199512283332604 · Cited by 1,492

Analysis of Intestinal Flora Development in Breast-Fed and Formula-Fed Infants by Using Molecular Identification and Detection Methods

Harmsen, H. J. M., Wildeboer-Veloo, A. C. M., Raangs, G. C., Wagendorp, A. A., Klijn, N., BINDELS, J. G., & Welling, G. W. (2000) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200001000-00019 · Cited by 1,326

Long-term ecological impacts of antibiotic administration on the human intestinal microbiota

Jernberg, C., Löfmark, S., Edlund, C., & Jansson, J. K. (2007) · The ISME Journal · doi:10.1038/ismej.2007.3 · Cited by 1,134

Temporal and spatial variation of the human microbiota during pregnancy

DiGiulio, D. B., Callahan, B. J., McMurdie, P. J., Costello, E. K., Lyell, D. J., Robaczewska, A., Sun, C. L., Goltsman, D. S. A., Wong, R. J., Shaw, G., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1502875112 · Cited by 1,129

A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome

Perez-Muñoz, M. E., Arrieta, M.-C., Ramer-Tait, A. E., & Walter, J. (2017) · Microbiome · doi:10.1186/s40168-017-0268-4 · Cited by 1,096

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

Chu, D. M., Ma, J., Prince, A. L., Antony, K. M., Seferovic, M. D., & Aagaard, K. M. (2017) · Nature Medicine · doi:10.1038/nm.4272 · Cited by 1,063

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

Yassour, M., Vatanen, T., Siljander, H., Hämäläinen, A.-M., Härkönen, T., Ryhänen, S. J., Franzosa, E. A., Vlamakis, H., Huttenhower, C., Gevers, D., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aad0917 · Cited by 1,043

Exploring Microbial Diversity and Taxonomy Using SSU rRNA Hypervariable Tag Sequencing

Huse, S. M., Dethlefsen, L., Huber, J. A., Welch, D. B. M., Relman, D. A., & Sogin, M. L. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000255 · Cited by 1,020

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

Dominguez-Bello, M. G., De Jesus-Laboy, K. M., Shen, N., Cox, L. M., Amir, A., Gonzalez, A., Bokulich, N. A., Song, S. J., Hoashi, M., Rivera-Vinas, J. I., et al. (2016) · Nature Medicine · doi:10.1038/nm.4039 · Cited by 1,014

Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section

Jakobsson, H. E., Abrahamsson, T. R., Jenmalm, M. C., Harris, K., Quince, C., Jernberg, C., Björkstén, B., Engstrand, L., & Andersson, A. F. (2014) · Gut · doi:10.1136/gutjnl-2012-303249 · Cited by 1,011

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months

Azad, M. B., Konya, T., Maughan, H., Guttman, D. S., Field, C. J., Chari, R. S., Sears, M. R., Becker, A. B., Scott, J. A., & Kozyrskyj, A. L. (2013) · Canadian Medical Association Journal · doi:10.1503/cmaj.121189 · Cited by 989

Topological-insulator-based terahertz modulator

Wang, X., Cheng, L., Wu, Y., Zhu, D., Wang, L., Zhu, J., Yang, H., & Chia, E. E. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-13701-9 · Cited by 983

Siblings, Day-Care Attendance, and the Risk of Asthma and Wheezing during Childhood

Ball, T. M., Castro-Rodríguez, J. A., Griffith, K. A., Holberg, C. J., Martínez, F. D., & Wright, A. L. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008243430803 · Cited by 946

The intestinal microflora in allergic Estonian and Swedish 2‐year‐old children

Björkstén, Naaber, P., Sepp, & Mikelsaar (1999) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1999.00560.x · Cited by 927

The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome

Sela, D. A., Chapman, J., Adeuya, A., Kim, J., Chen, F., Whitehead, T. R., Lapidus, A. L., Rokhsar, D. S., Lebrilla, C. B., German, J. B., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809584105 · Cited by 895

The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery

Cabrera-Rubio, R., Collado, M. C., Laitinen, K., Salminen, S., Isolauri, E., & Mira, A. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.037382 · Cited by 886

Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women

Collado, M. C., Isolauri, E., Laitinen, K., & Salminen, S. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.4.894 · Cited by 878

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes

Magnúsdóttir, S., Ravcheev, D., de Crécy-Lagard, V., & Thiele, I. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00148 · Cited by 876

Fecal Microflora in Healthy Infants Born by Different Methods of Delivery: Permanent Changes in Intestinal Flora After Cesarean Delivery

Grölund, M., Lehtonen, O. ‐., Eerola, E., & Kero, P. O. (1999) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-199901000-00007 · Cited by 873

Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women

Santacruz, A., Collado, M. C., García-Valdés, L., Segura, M. T., Martín-Lagos, J. A., Anjos, T., Martí-Romero, M., Lopez, R. M., Florido, J., Campoy, C., et al. (2010) · British Journal of Nutrition · doi:10.1017/s0007114510000176 · Cited by 868

The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women

Romero, R., Hassan, S. S., Gajer, P., Tarca, A. L., Fadrosh, D. W., Nikita, L., Galuppi, M., Lamont, R. F., Chaemsaithong, P., Miranda, J., et al. (2014) · Microbiome · doi:10.1186/2049-2618-2-4 · Cited by 852

Predicting Preschooler Obesity at Birth: The Role of Maternal Obesity in Early Pregnancy

Whitaker, R. C. (2004) · PEDIATRICS · doi:10.1542/peds.114.1.e29 · Cited by 817

Repeated, long-distance migrations by a philopatric predator targeting highly contrasting ecosystems

Lea, J. S. E., Wetherbee, B. M., Queiroz, N. C., Burnie, N., Aming, C., Sousa, L. L., Mucientes, G., Humphries, N. E., Harvey, G., SIMS, D. W., et al. (2015) · Scientific Reports · doi:10.1038/srep11202 · Cited by 809

Microbial Prevalence, Diversity and Abundance in Amniotic Fluid During Preterm Labor: A Molecular and Culture-Based Investigation

DiGiulio, D. B., Romero, R. J., Amogan, H., Kusanovic, J. P., Bik, E. M., Gotsch, F., Kim, C. J., Erez, O., Edwin, S. S., & Relman, D. A. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003056 · Cited by 808

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

Imhann, F., Vich Vila, A., Bonder, M. J., Fu, J., Gevers, D., Visschedijk, M. C., Spekhorst, L. M., Alberts, R., Franke, L., van Dullemen, H. M., et al. (2018) · Gut · doi:10.1136/gutjnl-2016-312135 · Cited by 788

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age

Bisgaard, H., Li, N., Bonnelykke, K., Chawes, B. L. K., Skov, T., Paludan-Müller, G., Stokholm, J., Smith, B., & Krogfelt, K. A. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.04.060 · Cited by 786

A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

Aagaard, K. M., Riehle, K. P., Ma, J., Segata, N., Mistretta, T., Coarfa, C., Raza, S., Rosenbaum, S., den Veyver, I. B. V., Milosavljevic, A., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036466 · Cited by 742

Intestinal microflora in early infancy: composition and development

Fanaro, S., Chierici, R., Guerrini, P., & Vigi, V. (2003) · Acta Paediatrica · doi:10.1111/j.1651-2227.2003.tb00646.x · Cited by 738

Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

Challier, J. C., Basu, S., Bintein, T., Minium, J., Hotmire, K., Catalano, P. M., & Hauguel-de Mouzon, S. (2008) · Placenta · doi:10.1016/j.placenta.2007.12.010 · Cited by 712 · cited 1×

The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: a systematic review

Rutayisire, E., Huang, K., Liu, Y., & Tao, F. (2016) · BMC Gastroenterology · doi:10.1186/s12876-016-0498-0 · Cited by 708

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

Korpela, K., Salonen, A., Virta, L. J., Kekkonen, R. A., Forslund, K., Bork, P., & de Vos, W. M. (2016) · Nature Communications · doi:10.1038/ncomms10410 · Cited by 698

Human milk glycobiome and its impact on the infant gastrointestinal microbiota

Zivkovic, A. M., German, J. B., Lebrilla, C. B., & Mills, D. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000083107 · Cited by 679

Establishment of the gut microbiota in Western infants

Adlerberth, I., & Wold, A. E. (2009) · Acta Paediatrica · doi:10.1111/j.1651-2227.2008.01060.x · Cited by 665

Abnormal bacterial colonisation of the genital tract and subsequent preterm delivery and late miscarriage

Hay, P. E., Lamont, R. F., Taylor-Robinson, D., Morgan, D. J., Ison, C., & Pearson, J. (1994) · BMJ · doi:10.1136/bmj.308.6924.295 · Cited by 651

Development of the gut microbiota in infancy and its impact on health in later life

Tanaka, M., & Nakayama, J. (2017) · Allergology International · doi:10.1016/j.alit.2017.07.010 · Cited by 639 · cited 2×

Evidence on the long-term effects of breastfeeding SYSTEMATIC REVIEWS AND META-ANALYSES

Horta, B. L. (2007) · Cited by 636

Microbes in the neonatal intensive care unit resemble those found in the gut of premature infants

Brooks, B., Firek, B., Miller, C. S., Sharon, I., Thomas, B. C., Baker, R. W., Morowitz, M. J., & Banfield, J. F. (2014) · Microbiome · doi:10.1186/2049-2618-2-1 · Cited by 627

Prolonged Initial Empirical Antibiotic Treatment is Associated with Adverse Outcomes in Premature Infants

Kuppala, V. S., Meinzen‐Derr, J. K., Morrow, A. L., & Schibler, K. R. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2011.05.033 · Cited by 618

The Microbial Ecology of the Large Bowel of Breastfed and Formula-fed Infants During the First Year of Life

Stark, P. L., & Lee, A. (1982) · Journal of Medical Microbiology · doi:10.1099/00222615-15-2-189 · Cited by 616

Meta-Analysis of Antibiotics and the Risk of Community-Associated Clostridium difficile Infection

Brown, K. A., Khanafer, N. L., Daneman, N., & Fisman, D. N. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02176-12 · Cited by 608

Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies

Cardwell, C. R., Stene, L. C., Joner, G., Cinek, O., Svensson, J., Goldacre, M. J., Parslow, R. C., Pozzilli, P., Brigis, G., Stoyanov, D., et al. (2008) · Diabetologia · doi:10.1007/s00125-008-0941-z · Cited by 590

The vaginal microbiome during pregnancy and the postpartum period in a European population

MacIntyre, D. A., Chandiramani, M., Lee, Y. S., Kindinger, L. M., Smith, A., Angelopoulos, N., Lehne, B. C., Arulkumaran, S., Brown, R., Teoh, T. G., et al. (2015) · Scientific Reports · doi:10.1038/srep08988 · Cited by 580

Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort

Hill, C. J., Lynch, D. B., Murphy, K., Ulaszewska, M., Jeffery, I. B., O’Shea, C. A., Watkins, C., Dempsey, E., Mattivi, F., Tuohy, K., et al. (2017) · Microbiome · doi:10.1186/s40168-016-0213-y · Cited by 573

Intestinal Microbiota of 6‐week‐old Infants Across Europe: Geographic Influence Beyond Delivery Mode, Breast‐feeding, and Antibiotics

Fallani, M., Young, D., Scott, J. A., Norin, E. L., Amarri, S., Adam, R., Aguilera, J., Khanna, S., Gil, Á., Edwards, C. A., et al. (2010) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181d1b11e · Cited by 559

The Host Genotype Affects the Bacterial Community in the Human Gastronintestinal Tract

Zoetendal, A. D. L. A. E. G. (2001) · Microbial Ecology in Health and Disease · doi:10.1080/089106001750462669 · Cited by 558

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota

O’Hanlon, D. E., Moench, T. R., & Cone, R. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080074 · Cited by 548

Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics

Ajslev, T. A., Andersen, C. S., Gamborg, M., Sørensen, T. I. A., & Jess, T. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.27 · Cited by 534 · cited 1×

Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis

Tojo, R. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i41.15163 · Cited by 533

Establishment of intestinal microbiota during early life: a longitudinal, explorative study of a large cohort of Danish infants

Bergström, A., Skov, T. H., Bahl, M. I., Roager, H. M., Christensen, L. B., Ejlerskov, K. T., Mølgaard, C., Michaelsen, K. F., & Licht, T. R. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.00342-14 · Cited by 532

The function of our microbiota: who is out there and what do they do?

Ottman, N., Smidt, H., de Vos, W. M., & Belzer, C. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00104 · Cited by 523

The crisis of no new antibiotics—what is the way forward?

Piddock, L. J. V. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70316-4 · Cited by 522

Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy

Gaillard, R., Durmuş, B., Albert Hofman, D., Mackenbach, J. P., Steegers, E. A. P., & Jaddoe, V. W. V. (2013) · Obesity · doi:10.1002/oby.20088 · Cited by 519

High-Throughput Sequencing Reveals the Incomplete, Short-Term Recovery of Infant Gut Microbiota following Parenteral Antibiotic Treatment with Ampicillin and Gentamicin

Fouhy, F., Guinane, C. M., Hussey, S., Wall, R., Ryan, C. A., Dempsey, E. M., Murphy, B. P., Ross, R. P., Fitzgerald, G. F., Stanton, C., et al. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00789-12 · Cited by 518

Breast Milk as the Gold Standard for Protective Nutrients

Walker, A. W. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2009.11.021 · Cited by 517

Infant antibiotic exposures and early-life body mass

Trasande, L., Blustein, J., Liu, M., Corwin, E. J., Cox, L. M., & Blaser, M. J. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.132 · Cited by 514

Association of Antibiotics in Infancy With Early Childhood Obesity

Bailey, L. C., Forrest, C. B., Zhang, P., Richards, T. M., Livshits, A., & DeRusso, P. A. (2014) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2014.1539 · Cited by 504

Caesarean delivery and risk of atopy and allergic disesase: meta‐analyses

Bager, P., Wohlfahrt, J., & Westergaard, T. (2008) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2008.02939.x · Cited by 503

Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy

van Nimwegen, F. A., Penders, J., Stobberingh, E. E., Postma, D. S., Koppelman, G. H., Kerkhof, M., Reijmerink, N. E., Dompeling, E., van den Brandt, P. A., Ferreira, I., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.07.027 · Cited by 493

Antibiotic use and inflammatory bowel diseases in childhood

Hviid, A. P., Svanström, H., & Frisch, M. (2010) · Gut · doi:10.1136/gut.2010.219683 · Cited by 492

Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease

Dubinkina, V. B., Tyakht, A., Odintsova, V. Y., Yarygin, K. S., Kovarsky, B. A., Pavlenko, A. V., Ischenko, D. S., Popenko, A., Alexeev, D. G., Taraskina, A. Y., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0359-2 · Cited by 472

Establishment and development of intestinal microbiota in preterm neonates

Arboleya, S., Binetti, A. G., Salazar, N., Fernández, N., Sánchez, G. S., Hernández‐Barranco, A. M., Margollés, A., Reyes‐Gavilán, C. G. D. L., & Gueimonde, M. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01261.x · Cited by 468

Cesarean Delivery May Affect the Early Biodiversity of Intestinal Bacteria1,

Biasucci, G., Benenati, B., Morelli, L., Bessi, E., & Boehm, G. (2008) · The Journal of Nutrition · doi:10.1093/jn/138.9.1796s · Cited by 458 · cited 4×

Developmental dynamics of the preterm infant gut microbiota and antibiotic resistome

Gibson, M. K., Wang, B., Ahmadi, S., Burnham, C.-A. D., Tarr, P. I., Warner, B. B., & Dantas, G. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.24 · Cited by 457

High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model

Ma, J., Prince, A., Bader, D., Hu, M., Ganu, R., Baquero, K. C., Blundell, P., Harris, R. A., Frias, A. E., Grove, K. L., et al. (2014) · Nature Communications · doi:10.1038/ncomms4889 · Cited by 452

Cumulative Antibiotic Exposures Over Time and the Risk of Clostridium difficile Infection

Stevens, V. W., Dumyati, G. K., Fine, L., Fisher, S. G., & van Wijngaarden, E. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir301 · Cited by 447

Variation of human milk oligosaccharides in relation to milk groups and lactational periods

Thurl, S., Munzert, M., Henker, J., Boehm, G., Müller‐Werner, B., Jelinek, J., & Stahl, B. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510002072 · Cited by 438

Influence of mode of delivery on gut microbiota composition in seven year old children: Table 1

Salminen, S., Gibson, G. R., McCartney, A. L., & Isolauri, E. (2004) · Gut · doi:10.1136/gut.2004.041640 · Cited by 435

Long-term follow-up and pregnancy after complete sacrectomy with lumbopelvic reconstruction: case report and literature review

Barsan, V. V., Briceño, V., Gandhi, M., & Jea, A. H. (2016) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-015-0735-5 · Cited by 435

The Intestinal Microflora of Infants: Composition of Fecal Flora in Breast‐Fed and Bottle‐Fed Infants

Benno, Y., Sawada, K., & MITSUOKA, T. (1984) · Microbiology and Immunology · doi:10.1111/j.1348-0421.1984.tb00754.x · Cited by 432

Contributions of tropodithietic acid and biofilm formation to the probiotic activity of Phaeobacter inhibens

Zhao, W., Dao, C. A., Karim, M., Marta Gómez-chiarri, G., Rowley, D. C., & Nelson, D. R. (2016) · BMC Microbiology · doi:10.1186/s12866-015-0617-z · Cited by 424

Early Empiric Antibiotic Use in Preterm Infants Is Associated with Lower Bacterial Diversity and Higher Relative Abundance of Enterobacter

Greenwood, C., Morrow, A. L., Lagomarcino, A. J., Altaye, M., Taft, D. H., Yu, Z., Newburg, D. S., Ward, D. V., & Schibler, K. R. (2014) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2014.01.010 · Cited by 416

Adverse Effects on Offspring of Maternal Alcohol Abuse during Pregnancy

Ouellette, E. M., Rosett, H. L., Rosman, N. P., & Weiner, L. (1977) · New England Journal of Medicine · doi:10.1056/nejm197709082971003 · Cited by 416

Reported Medication Use in the Neonatal Intensive Care Unit: Data From a Large National Data Set

Clark, R. H., Bloom, B. T., Spitzer, A. R., & Gerstmann, D. R. (2006) · PEDIATRICS · doi:10.1542/peds.2005-1707 · Cited by 414

Bacterial Diversity in Meconium of Preterm Neonates and Evolution of Their Fecal Microbiota during the First Month of Life

Moles, L., Gómez, M., Heilig, H. G. H. J., Bustos, G., Fuentes, S., de Vos, W. M., Fernández, L., Rodríguez, J. M., & Jiménez, E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066986 · Cited by 400

Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota

Tanaka, S., Kobayashi, T., Songjinda, P., Tateyama, A., Tsubouchi, M., Kiyohara, C., Shirakawa, T., Sonomoto, K., & Nakayama, J. (2009) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2009.00553.x · Cited by 396

Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis

Alexander, V. N., Northrup, V. S., & Bizzarro, M. J. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2011.02.035 · Cited by 394

The ‘microflora hypothesis’ of allergic diseases

Noverr, M. C., & Huffnagle, G. B. (2005) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2005.02379.x · Cited by 394

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

McGovern, D. P. B., Jones, M. R., Taylor, K. D., Marciante, K. D., Yan, X., Dubinsky, M. C., Ippoliti, A., Vasiliauskas, E. A., Berel, D., Derkowski, C. A., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq248 · Cited by 391

Effect of Breast and Formula Feeding on Gut Microbiota Shaping in Newborns

Guaraldi, F., & Salvatori, G. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00094 · Cited by 384

Effect of mother’s weight on infant’s microbiota acquisition, composition, and activity during early infancy: a prospective follow-up study initiated in early pregnancy

Collado, M. C., Isolauri, E., Laitinen, K., & Salminen, S. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29877 · Cited by 381

Effect of breast feeding on risk of coeliac disease: a systematic review and meta-analysis of observational studies

Akobeng, A. K. (2005) · Archives of Disease in Childhood · doi:10.1136/adc.2005.082016 · Cited by 380

Impact of maternal probiotic-supplemented dietary counselling on pregnancy outcome and prenatal and postnatal growth: a double-blind, placebo-controlled study

Luoto, R., Laitinen, K., Nermes, M., & Isolauri, E. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114509993898 · Cited by 370

Short-Term Effect of Antibiotics on Human Gut Microbiota

Panda, S., khader, I. E., Casellas, F., Vivancos, J., Cors, M. G., Santiago, A., Cuenca, S., Guarner, F., & Manichanh, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095476 · Cited by 364

Dynamics of Infant Gut Microbiota Are Influenced by Delivery Mode and Gestational Duration and Are Associated with Subsequent Adiposity

Dogra, S. K., Sakwińska, O., Soh, S., Ngom‐Bru, C., Brück, W. M., Berger, B. W., Brüssow, H., Lee, Y. S., Yap, F. K. P., Chong, Y. S., et al. (2015) · mBio · doi:10.1128/mbio.02419-14 · Cited by 359

Stool microflora in extremely low birthweight infants

Gewolb, I. H., Schwalbe, R. S., Taciak, V. L., Harrison, T. S., & Panigrahi, P. (1999) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/fn.80.3.f167 · Cited by 355

Mode of Delivery – Effects on Gut Microbiota and Humoral Immunity

Huurre, A., Kalliomäki, M. A., Rautava, S., Rinne, M., Salminen, S., & Isolauri, E. (2007) · Neonatology · doi:10.1159/000111102 · Cited by 354

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 ( Secretor ) genotype

Rausch, P., Rehman, A., Künzel, S., Häsler, R., Ott, S. J., Schreiber, S., Rosenstiel, P. C., Franke, A., & Baines, J. F. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106408108 · Cited by 351

Asymptomatic bacterial vaginosis and intermediate flora as risk factors for adverse pregnancy outcome

Leitich, H., & Kiss, H. (2007) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2006.12.005 · Cited by 342

New Insights in Gut Microbiota Establishment in Healthy Breast Fed Neonates

Jost, T., Lacroix, C., Braegger, C., & Chassard, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044595 · Cited by 342

Antibiotic-Associated Diarrhea Accompanied by Large-Scale Alterations in the Composition of the Fecal Microbiota

Young, V. B., & Schmidt, T. M. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.3.1203-1206.2004 · Cited by 337

Development of the Intestinal Bacterial Composition in Hospitalized Preterm Infants in Comparison with Breast-Fed, Full-Term Infants

Schwiertz, A., Gruhl, B., Löbnitz, M., Michel, P., Radke, M. H., & Blaut, M. (2003) · Pediatric Research · doi:10.1203/01.pdr.0000078274.74607.7a · Cited by 335

Resilience of the Dominant Human Fecal Microbiota upon Short-Course Antibiotic Challenge

Cochetiere, M. F. D. L., Durand, T., Lepage, P., Bourreille, A., Galmiche, J. P., & Dore, J. M. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.11.5588-5592.2005 · Cited by 333

The Human Neonatal Gut Microbiome: A Brief Review

Gritz, E. C., & Bhandari, V. (2015) · Frontiers in Pediatrics · doi:10.3389/fped.2015.00017 · Cited by 323

Human milk oligosaccharide consumption by intestinal microbiota

Marcobal, A. M., & Sonnenburg, J. L. (2012) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2012.03863.x · Cited by 317

Probiotics and dietary counselling contribute to glucose regulation during and after pregnancy: a randomised controlled trial

Laitinen, K., Poussa, T. A., Isolauri, E., & the Nutrition, A. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508111461 · Cited by 315

Distinct distal gut microbiome diversity and composition in healthy children from Bangladesh and the United States

Lin, A., Bik, E. M., Costello, E. K., Dethlefsen, L., Haque, R., Relman, D. A., & Singh, U. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053838 · Cited by 314

Is There Any Practical Application of Meta-Analytical Results in Strength Training?

Gentil, P., Arruda, A. C. P., Souza, D., Gießing, J., Paoli, A., Fisher, J. P., & Steele, J. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00001 · Cited by 309

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

Brown, R. G., Marchesi, J. R., Lee, Y. S., Smith, A., Lehne, B., Kindinger, L. M., Terzidou, V., Holmes, E., Nicholson, J. K., Bennett, P. R., et al. (2018) · BMC Medicine · doi:10.1186/s12916-017-0999-x · Cited by 295

Connections Between the Gut Microbiome and Metabolic Hormones in Early Pregnancy in Overweight and Obese Women

Gomez-Arango, L. F., Barrett, H. L., McIntyre, H. D., Callaway, L. K., Morrison, M., & Dekker Nitert, M. (2016) · Diabetes · doi:10.2337/db16-0278 · Cited by 287

The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis

Prince, A., Ma, J., Kannan, P. S., Alvarez, M., Gisslen, T. A., Harris, R. A., Sweeney, E. L., Knox, C. L., Lambers, D. S., Jobe, A. H., et al. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.01.193 · Cited by 282

Early exposure to infections and antibiotics and the incidence of allergic disease: A birth cohort study with the West Midlands General Practice Research Database

McKeever, T. M., Lewis, S., Smith, C., Collins, J. S., Heatlie, H., Frischer, M., & Hubbard, R. (2002) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2002.121016 · Cited by 276

Maternal weight and excessive weight gain during pregnancy modify the immunomodulatory potential of breast milk

Collado, M. C., Laitinen, K., Salminen, S., & Isolauri, E. (2012) · Pediatric Research · doi:10.1038/pr.2012.42 · Cited by 275

Transmission of Diverse Oral Bacteria to Murine Placenta: Evidence for the Oral Microbiome as a Potential Source of Intrauterine Infection

Fardini, Y., Chung, P., Dumm, R., Joshi, N., & Han, Y. W. (2010) · Infection and Immunity · doi:10.1128/iai.01395-09 · Cited by 272

Maternal diet during pregnancy is related with the infant stool microbiome in a delivery mode-dependent manner

Lundgren, S., Madan, J. C., Emond, J. A., Morrison, H. G., Christensen, B. C., Karagas, M. R., & Hoen, A. G. (2018) · Microbiome · doi:10.1186/s40168-018-0490-8 · Cited by 271

A Physiological Role of Breast Milk Leptin in Body Weight Control in Developing Infants

Miralles, O., Sánchez, J., Palou, A., & Picó, C. (2006) · Obesity · doi:10.1038/oby.2006.155 · Cited by 267

Impact of human milk bacteria and oligosaccharides on neonatal gut microbiota establishment and gut health

Jost, T., Lacroix, C., Braegger, C., & Chassard, C. (2015) · Nutrition Reviews · doi:10.1093/nutrit/nuu016 · Cited by 267

Diversified Microbiota of Meconium Is Affected by Maternal Diabetes Status

Hu, J., Nomura, Y., Bashir, A., Fernandez-Hernandez, H., Itzkowitz, S. H., Pei, Z., Stone, J. L., Loudon, H., & Peter, I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078257 · Cited by 265

Is delivery by cesarean section a risk factor for food allergy?

Eggesbø, M. Å., Botten, G., Stigum, H., Nafstad, P. H. J., & Magnus, P. M. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.1610 · Cited by 255

The human gut microbiota: a dynamic interplay with the host from birth to senescence settled during childhood

Putignani, L., CHIERICO, F. D., Petrucca, A., Vernocchi, P., & Dallapiccola, B. (2014) · Pediatric Research · doi:10.1038/pr.2014.49 · Cited by 249

Comparative Metagenomics and Population Dynamics of the Gut Microbiota in Mother and Infant

Vaishampayan, P., Kuehl, J. V., Froula, J. L., Morgan, J. L., Ochman, H., & Francino, M. P. (2010) · Genome Biology and Evolution · doi:10.1093/gbe/evp057 · Cited by 248

Gut Microbiome of Coexisting BaAka Pygmies and Bantu Reflects Gradients of Traditional Subsistence Patterns

Gomez, A., Petrzelkova, K. J., Burns, M. B., Yeoman, C. J., Amato, K. R., Vlckova, K., Modry, D., Todd, A., Jost Robinson, C. A., Remis, M. J., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.02.013 · Cited by 248 · cited 1×

Gut Microbiome Developmental Patterns in Early Life of Preterm Infants: Impacts of Feeding and Gender

Cong, X. S., Xu, W., Janton, S., Henderson, W. A., Matson, A. P., McGrath, J. M., Maas, K. R., & Graf, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152751 · Cited by 245

Untitled work

(1998) · PubMed · Cited by 239

The Early Settlers: Intestinal Microbiology in Early Life

Scholtens, P. A. M. J., Oozeer, R., Martı́n, R., Amor, K. B., & Knol, J. (2012) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-022811-101120 · Cited by 231

Family structure, neonatal infection, and hay fever in adolescence.

Strachan, D. P., Taylor, E., & Carpenter, R. G. (1996) · Archives of Disease in Childhood · doi:10.1136/adc.74.5.422 · Cited by 226

The Human Gut Microbiome as a Transporter of Antibiotic Resistance Genes between Continents

Bengtsson‐Palme, J., Angelin, M., Huss, M., Kjellqvist, S., Kristiansson, E., Palmgren, H., Larsson, D. G. J., & Johansson, A. F. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00933-15 · Cited by 226

Pregnancy Outcome and Risk of Celiac Disease in Offspring: A Nationwide Case-Control Study

Mårild, K., Stephansson, O., Montgomery, S., Murray, J. A., & Ludvigsson, J. F. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.09.047 · Cited by 218

Determining the Long-term Effect of Antibiotic Administration on the Human Normal Intestinal Microbiota Using Culture and Pyrosequencing Methods

Rashid, M.-U., Zaura, E., Buijs, M. J., Keijser, B. J. F., Crielaard, W., Nord, C. E., & Weintraub, A. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ137 · Cited by 214

Risks of Overweight and Abdominal Obesity at Age 16 Years Associated With Prenatal Exposures to Maternal Prepregnancy Overweight and Gestational Diabetes Mellitus

Pirkola, J., Pouta, A., Bloigu, A., Hartikainen, A.-L., Laitinen, J., Järvelin, M.-R., & Vääräsmäki, M. (2010) · Diabetes Care · doi:10.2337/dc09-1871 · Cited by 214

Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism

Tong, M., McHardy, I. H., Ruegger, P. M., Goudarzi, M., Kashyap, P., Haritunians, T., Li, X., Graeber, T. G., Schwager, E., Huttenhower, C., et al. (2014) · The ISME Journal · doi:10.1038/ismej.2014.64 · Cited by 213

Early life colonization of the human gut: microbes matter everywhere

Korpela, K., & de Vos, W. M. (2018) · Current Opinion in Microbiology · doi:10.1016/j.mib.2018.06.003 · Cited by 211

Investigations into the influence of host genetics on the predominant eubacteria in the faecal microflora of children

Stewart, J. A., CHADWICK, V. S., & Murray, A. (2005) · Journal of Medical Microbiology · doi:10.1099/jmm.0.46189-0 · Cited by 208

Breastfeeding, Childhood Asthma, and Allergic Disease

Oddy, W. H. (2017) · Annals of Nutrition and Metabolism · doi:10.1159/000457920 · Cited by 207

Relationship of bacterial vaginosis and mycoplasmas to the risk of spontaneous abortion

Donders, G. G. G., Bulck, B. V., Caudron, J., Londers, L., Vereecken, A. J., & Spitz, B. (2000) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2000.105738 · Cited by 204

Pregnancy-related changes in the maternal gut microbiota are dependent upon the mother's periconceptional diet

Gohir, W., Whelan, F. J., Surette, M. G., Moore, C., Schertzer, J. D., & Sloboda, D. M. (2015) · Gut Microbes · doi:10.1080/19490976.2015.1086056 · Cited by 203

Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes

Baumann-Dudenhoeffer, A. M., D’Souza, A. W., Tarr, P. I., Warner, B. B., & Dantas, G. A. (2018) · Nature Medicine · doi:10.1038/s41591-018-0216-2 · Cited by 203

Structural and Functional Aspects of Prebiotics Used in Infant Nutrition1,

Boehm, G., & Moro, G. E. (2008) · Journal of Nutrition · doi:10.1093/jn/138.9.1818s · Cited by 202

Correction: Development of an Agent-Based Model (ABM) to Simulate the Immune System and Integration of a Regression Method to Estimate the Key ABM Parameters by Fitting the Experimental Data

Tong, X., Chen, J., Miao, H., Li, T., & Zhang, L. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156823 · Cited by 198

The vaginal microbiome of pregnant women is less rich and diverse, with lower prevalence of Mollicutes, compared to non-pregnant women

Freitas, A. C., Chaban, B. L., Bocking, A. D., Rocco, M., Yang, S., Hill, J. E., Money, D., Hemmingsen, S. M., Reid, G., Dumonceaux, T., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07790-9 · Cited by 198

Mode of delivery and development of atopic disease during the first 2 years of life

Negele, K., Heinrich, J., Borte, M., Berg, A. V., Schaaf, B., Lehmann, I., Wichmann, H. ‐., Bolte, G., & for the LISA Study Group (2004) · Pediatric Allergy and Immunology · doi:10.1046/j.0905-6157.2003.00101.x · Cited by 197

Rapidly expanding knowledge on the role of the gut microbiome in health and disease

Cénit, M. C., Matzaraki, V., Tigchelaar, E. F., & Zhernakova, A. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.05.023 · Cited by 197

First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota

Hansen, R., Scott, K. P., Khan, S., Martin, J. C., Berry, S. H., Stevenson, M. D., Augusta, O., Munro, M. J., & Hold, G. L. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133320 · Cited by 194

Breast feeding

Hoddinott, P., Tappin, D. M., & Wright, C. M. (2008) · BMJ · doi:10.1136/bmj.39521.566296.be · Cited by 194

Molecular genetic analysis of the human Lewis histo-blood group system.

Nishihara, S., Narimatsu, H., Iwasaki, H., Yazawa, S., Akamatsu, S., Ando, T., Seno, T., & Narimatsu, I. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)62041-7 · Cited by 190

Impact of maternal nutrition in pregnancy and lactation on offspring gut microbial composition and function

Chu, D. M., Meyer, K. M., Prince, A., & Aagaard, K. M. (2016) · Gut Microbes · doi:10.1080/19490976.2016.1241357 · Cited by 188

Pregnancy's Stronghold on the Vaginal Microbiome

Walther-Antonio, M. R. S., Jeraldo, P., Miller, M. E. B., Yeoman, C. J., Nelson, K. E., Wilson, B. A., White, B. A., Chia, N., & Creedon, D. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098514 · Cited by 187

Oligosaccharides from human milk influence growth-related characteristics of intestinally transformed and non-transformed intestinal cells

Kuntz, S., Rudloff, S., & Kunz, C. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507824068 · Cited by 186

Maternal Obesity Is Associated with Alterations in the Gut Microbiome in Toddlers

Galley, J. D., Bailey, M. T., Dush, C. M. K., Schoppe‐Sullivan, S. J., & Christian, L. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113026 · Cited by 184

Exposure to furry pets and the risk of asthma and allergic rhinitis: a meta‐analysis

Takkouche, B., González‐Barcala, F. ‐., Etminan, M., & FitzGerald, M. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01732.x · Cited by 180 · cited 2×

Gut Microbiota in the First 2 Years of Life and the Association with Body Mass Index at Age 12 in a Norwegian Birth Cohort

Stanislawski, M. A., Dabelea, D., Wagner, B. D., Iszatt, N., Dahl, C., Sontag, M. K., Knight, R. D., Lozupone, C., & Eggesbø, M. Å. (2018) · mBio · doi:10.1128/mbio.01751-18 · Cited by 179

Incidence of pelvic inflammatory disease after first-trimester legal abortion in women with bacterial vaginosis after treatment with metronidazole: A double-blind, randomized study

Larsson, P., Platz‐Christensen, J., Thejls, H., Forsum, U., & Påhlson, C. (1992) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(92)91838-2 · Cited by 178

The Carriage ofEscherichia coliResistant to Antimicrobial Agents by Healthy Children in Boston, in Caracas, Venezuela, and in Qin Pu, China

Lester, S. C., Pla, M. D. P., Wang, F., Schael, I. P., Jiang, H., & O’Brien, T. (1990) · New England Journal of Medicine · doi:10.1056/nejm199008023230501 · Cited by 176

Antibiotic exposure and the development of coeliac disease: a nationwide case–control study

Mårild, K., Ye, W., Lebwohl, B., Green, P. H., Blaser, M. J., Card, T., & Ludvigsson, J. F. (2013) · BMC Gastroenterology · doi:10.1186/1471-230x-13-109 · Cited by 175

Impact of Westernized Diet on Gut Microbiota in Children on Leyte Island

Nakayama, J., Yamamoto, A., Conde, L. A., Higashi, K., Sonomoto, K., Tan, J. D., & Lee, Y. K. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00197 · Cited by 171

Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: A randomized, double-blind, placebo-controlled trial

Karamali, M., Dadkhah, F., Sadrkhanlou, M., Jamilian, M., Ahmadi, S., Ebrahimi, M. T., Jafari, P., & Asemi, Z. (2016) · Diabetes & Metabolism · doi:10.1016/j.diabet.2016.04.009 · Cited by 170

Micrococci and Peptidoglycan Activate TLR2→MyD88→IRAK→TRAF→NIK→IKK→NF-κB Signal Transduction Pathway That Induces Transcription of Interleukin-8

Wang, Q., Dziarski, R., Kirschning, C. J., Muzio, M., & Gupta, D. (2001) · Infection and Immunity · doi:10.1128/iai.69.4.2270-2276.2001 · Cited by 169

Antibiotic Use in Neonatal Intensive Care Units and Adherence With Centers for Disease Control and Prevention 12 Step Campaign to Prevent Antimicrobial Resistance

Patel, S., Oshodi, A., Prasad, P. A., DeLaMora, P. A., Larson, E., Zaoutis, T., Paul, D. A., & Saiman, L. M. (2009) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181b12484 · Cited by 164

Long-term follow-up of infants of mothers with type 1 diabetes: evidence for hereditary and nonhereditary transmission of diabetes and precursors.

Weiss, P., Scholz, H.-P., Haas, J., Tamussino, K. F., Seißler, J., & Borkenstein, M. H. (2000) · Diabetes Care · doi:10.2337/diacare.23.7.905 · Cited by 164

Role of MyD88 in Diminished Tumor Necrosis Factor Alpha Production by Newborn Mononuclear Cells in Response to Lipopolysaccharide

Yan, S. R., Qing, G., Byers, D. M., Stadnyk, A. W., Al‐Hertani, W., & Bortolussi, R. A. (2004) · Infection and Immunity · doi:10.1128/iai.72.3.1223-1229.2004 · Cited by 163

Maternal Antibiotic Treatment Impacts Development of the Neonatal Intestinal Microbiome and Antiviral Immunity

Gonzalez-Perez, G., Hicks, A. L., Tekieli, T. M., Radens, C. M., Williams, B. L., & Lamousé-Smith, E. S. N. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502322 · Cited by 161

Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study)

Lindsay, K. L., Kennelly, M. A., Culliton, M., Smith, T., Maguire, O. C., Shanahan, F., Brennan, L., & McAuliffe, F. M. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.079723 · Cited by 160

Correction: Corrigendum: Structural and compositional dependence of the CdTexSe1−x alloy layer photoactivity in CdTe-based solar cells

Poplawsky, J. D., Guo, W. H., Paudel, N. R., Ng, A., More, K. L., Leonard, D. N., & Yan, Y. (2016) · Nature Communications · doi:10.1038/ncomms12831 · Cited by 160

Peripartum Antibiotics Promote Gut Dysbiosis, Loss of Immune Tolerance, and Inflammatory Bowel Disease in Genetically Prone Offspring

Miyoshi, J., Bobe, A. M., Miyoshi, S., Huang, Y., Hubert, N., Delmont, T. O., Eren, A. M., Leone, V., & Chang, E. B. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.06.060 · Cited by 156

Acquired Antibiotic Resistance: Are We Born with It?

Zhang, L., Kinkelaar, D. F., Huang, Y., Li, Y., Li, X., & Wang, H. H. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.05087-11 · Cited by 155

Influence of Milk-Feeding Type and Genetic Risk of Developing Coeliac Disease on Intestinal Microbiota of Infants: The PROFICEL Study

Palma, G. D., Capilla, A., Nova, E., Castillejo, G., Varea, V., Pozo, T., Garrote, J. A., Polanco, I., López, A., Ribes‐Koninckx, C., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030791 · Cited by 150

Serum IgE levels in white and metis communities in Saskatchewan.

GERRARD, J. W., Geddes, C., Reggin, P. L., Cd, G., & Horne, S. (1976) · PubMed · Cited by 145

Investigation of the intestinal microbiota in preterm infants using different methods

Rougé, C., Goldenberg, O., Ferraris, L., Berger, B. W., Rochat, F., Legrand, A., Göbel, U. B., Vodovar, M., Voyer, M., Rozé, J., et al. (2010) · Anaerobe · doi:10.1016/j.anaerobe.2010.06.002 · Cited by 141

Low species diversity and high interindividual variability in faeces of preterm infants as revealed by sequences of 16S rRNA genes and PCR-temporal temperature gradient gel electrophoresis profiles

Magne, F., Abély, M., Boyer, F., Morville, P., Pochart, P., & Suau, A. (2006) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2006.00097.x · Cited by 140

Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial

Dolatkhah, N., Hajifaraji, M., Abbasalizadeh, F., Aghamohammadzadeh, N., Mehrabi, Y., & Abbasi, M. M. (2015) · Journal of Health Population and Nutrition · doi:10.1186/s41043-015-0034-9 · Cited by 137

Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial

Lindsay, K. L., Brennan, L., Kennelly, M. A., Maguire, O. C., Smith, T., Curran, S., Coffey, M., Foley, M. E., Hatunic, M., Shanahan, F., et al. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.02.008 · Cited by 136

Effects of a Multispecies Probiotic Mixture on Glycemic Control and Inflammatory Status in Women with Gestational Diabetes: A Randomized Controlled Clinical Trial

Jafarnejad, S., Saremi, S., Jafarnejad, F., & Arab, A. (2016) · Journal of Nutrition and Metabolism · doi:10.1155/2016/5190846 · Cited by 135

Antibiotic exposure in early infancy and risk for childhood atopy

Johnson, C. C., Ownby, D. R., Alford, S. H., Havstad, S. L., Williams, L. K., Zoratti, E. M., Peterson, E. L., & Joseph, C. L. M. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.04.020 · Cited by 132

Molecular Genetic Analysis of the Human Lewis Histo-blood Group System

Kudo, T., Iwasaki, H., Nishihara, S., Shinya, N., Ando, T., Narimatsu, I., & Narimatsu, H. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.16.9830 · Cited by 131

Intestinal colonisation patterns in breastfed and formula-fed infants during the first 12 weeks of life reveal sequential microbiota signatures

Timmerman, H. M., Rutten, N. B. M. M., Boekhorst, J., Saulnier, D. M. A., Kortman, G. A. M., Contractor, N., Kullen, M. J., Floris, E., Harmsen, H. J. M., Vlieger, A. M., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-08268-4 · Cited by 128

Bacterial vaginosis in pregnancy and the risk of prematurity: a meta-analysis.

Flynn, C. A., Helwig, A., & Meurer, L. N. (1999) · PubMed · Cited by 127

Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases

Bertelsen, R. J., Brantsæter, A. L., Magnus, M. C., Haugen, M. A., Myhre, R., Jacobsson, B., Longnecker, M. P., Meltzer, H. M., & London, S. J. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.07.032 · Cited by 123

Gestational diabetes is associated with changes in placental microbiota and microbiome

Bassols, J., Sérino, M., Carreras‐Badosa, G., Burcelin, R., Blasco‐Baqué, V., López‐Bermejo, A., & Fernández‐Real, J. M. (2016) · Pediatric Research · doi:10.1038/pr.2016.155 · Cited by 123

Association of bacterial vaginosis with a history of second trimester miscarriage

Llahí-Camp, J. M., Rai, R., Ison, C. A., Regan, L., & TAYLOR‐ROBINSON, D. (1996) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a019440 · Cited by 115

The Association Between Maternal Glucose Concentration and Child BMI at Age 3 Years

Deierlein, A. L., Siega‐Riz, A. M., Chantala, K., & Herring, A. H. (2011) · Diabetes Care · doi:10.2337/dc10-1766 · Cited by 113

Diet during Pregnancy and Infancy and the Infant Intestinal Microbiome

Savage, J. H., Lee‐Sarwar, K. A., Sordillo, J. E., Lange, N. E., Zhou, Y., O’Connor, G. T., Sandel, M. T., Bacharier, L. B., Zeiger, R. S., Sodergren, E. J., et al. (2018) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2018.07.066 · Cited by 112

Antibiotic‐associated diarrhoea and Clostridium difficile> in the community

Beaugerie, L., Flahault, A., Barbut, F., Atlan, P., Lalande, V., Cousin, P., Cadilhac, M., Petit, J., & FOR THE STUDY GROUP (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01531.x · Cited by 107

Antibiotic Treatment of Pregnant Non‐Obese Diabetic Mice Leads to Altered Gut Microbiota and Intestinal Immunological Changes in the Offspring

Tormo-Badia, N., Håkansson, Å., Vasudevan, K., Molin, G., Ahrné, S., & Cilio, C. (2014) · Scandinavian Journal of Immunology · doi:10.1111/sji.12205 · Cited by 102

Intake of probiotic food and risk of spontaneous preterm delivery

Myhre, R., Brantsæter, A. L., Myking, S., Gjessing, H. K., Sengpiel, V., Meltzer, H. M., Haugen, M. A., & Jacobsson, B. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.004085 · Cited by 102

Microbiome profile of the amniotic fluid as a predictive biomarker of perinatal outcome

Urushiyama, D., Suda, W., Ohnishi, E., Araki, R., Kiyoshima, C., Kurakazu, M., Sanui, A., Yotsumoto, F., 村田, 将., Nabeshima, K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-11699-8 · Cited by 101

Availability of intestinal microbial lysine for whole body lysine homeostasis in human subjects

Metges, C. C., El-Khoury, A. E., Henneman, L., Petzke, K. J., Grant, I., Bedri, S., Pereira, P. P., Ajami, A. M., Fuller, M. F., & Young, V. R. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.4.e597 · Cited by 100

Antibiotic treatment at delivery shapes the initial oral microbiome in neonates

Gómez-Arango, L. F., Barrett, H. L., McIntyre, D. H., Callaway, L. K., Morrison, M., & Nitert, M. D. (2017) · Scientific Reports · doi:10.1038/srep43481 · Cited by 97

Does breastfeeding influence the risk of developing diabetes mellitus in children? A review of current evidence

Pereira, P. F., Alfenas, R. D. C. G., & Araújo, R. M. A. (2014) · Jornal de Pediatria · doi:10.1016/j.jped.2013.02.024 · Cited by 89

Mucosa-Associated Bacterial Diversity in Necrotizing Enterocolitis

Brower–Sinning, R., Zhong, D., Good, M. L., Firek, B., Baker, R. W., Sodhi, C. P., Hackam, D. J., & Morowitz, M. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105046 · Cited by 88

Gestational diabetes, atopic dermatitis, and allergen sensitization in early childhood

Kumar, R., Ouyang, F., Story, R. E., Pongracic, J. A., Hong, X., Wang, G., Pearson, C., Ortiz, K., Bauchner, H., & Wang, X. (2009) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.06.052 · Cited by 88

Risk Factors for Extended Duration of Acute Diarrhea in Young Children

Strand, T. A., Sharma, P. R., Gjessing, H. K., Ulak, M., Chandyo, R., Adhikari, R., & Sommerfelt, H. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036436 · Cited by 86

Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health

Berding, K., Vlckova, K., Marx, W., Schellekens, H., Stanton, C., Clarke, G., Jacka, F., Dinan, T. G., & Cryan, J. F. (2021) · Advances in Nutrition · doi:10.1093/advances/nmaa181 · Cited by 451

Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Sözener, Z. Ç., Öztürk, B. Ö., Çerçi, P., Türk, M., Akın, B. G., Akdiş, M., Altıner, S., Yücel, Ü. Ö., Öğülür, İ., Mitamura, Y., et al. (2022) · Allergy · doi:10.1111/all.15240 · Cited by 455

Intestinal flora and disease mutually shape the regional immune system in the intestinal tract

Zhou, B., Yuan, Y., Zhang, S., Guo, C., Li, X., Li, G., Xiong, W., & Zeng, Z. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00575 · Cited by 396

Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma

Depner, M., Taft, D. H., Kirjavainen, P. V., Kalanetra, K. M., Karvonen, A. M., Peschel, S., Schmaußer‐Hechfellner, E., Roduit, C., Frei, R., Lauener, R. P., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1095-x · Cited by 382

The Association between Early-Life Gut Microbiota and Long-Term Health and Diseases

Sarkar, A., Yoo, J. Y., Dutra, S. V. O., Morgan, K. H., & Groer, M. E. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10030459 · Cited by 371

Prenatal and early childhood development of gut microbiota.

Adamek, K., Skonieczna‐Żydecka, K., Węgrzyn, D., & Łoniewska, B. (2019) · PubMed · doi:10.26355/eurrev_201911_19461 · Cited by 16

Microbiota of the Gastrointestinal Tract in Infancy

Jensen, E. T., Bertelsen, R. J., & Ringel‐Kulka, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804024-9.00003-3 · Cited by 7

Development of the gut microbiota and dysbiosis in children

Akagawa, S., Akagawa, Y., Yamanouchi, S., Kimata, T., Tsuji, S., & Kaneko, K. (2020) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.2020-034 · Cited by 38

The nature of gut microbiota in early life

van Best, N. (2021) · Research Publications (Maastricht University) · doi:10.26481/dis.20210430nb

The composition of the gut microbiota throughout life, with an emphasis on early life

Rodríguez, J. M., Murphy, K., Stanton, C., Ross, R. P., Kober, O. I., Juge, N., Avershina, E., Rudi, K., Narbad, A., Jenmalm, M. C., et al. (2015) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v26.26050 · Cited by 1,414