A common functional brain network for autobiographical, episodic, and semantic memory retrieval
Abstract
The objective of this study was to delineate a common functional network that underlies autobiographical, episodic, and semantic memory retrieval. We conducted an event-related fMRI study in which we utilized the same pictorial stimuli, but manipulated retrieval demands to extract autobiographical, episodic, or semantic memories. To assess this common network, we first examined the functional connectivity of regions identified by a previous analysis of task-related activity that were active across all three tasks. Three of these regions (left hippocampus, left lingual gyrus, and right caudate nucleus) appeared to share a common pattern of connectivity. This was confirmed in a subsequent functional connectivity analysis using these three regions as seeds. The results of this analysis showed that there was a pattern of functional connectivity that characterized all three seeds and that was common across the three retrieval conditions. Activity in inferior frontal and middle temporal cortex bilaterally, left temporoparietal junction, and anterior and posterior cingulate gyri was positively correlated with the seeds, whereas activity in posterior occipito-temporo-parietal regions was negatively correlated. These findings support the idea that a common neural network underlies the retrieval of declarative memories regardless of memory content. This proposed network consists of increased activity in regions that represent internal processes of memory retrieval and decreased activity in regions that mediate attention to external stimuli.
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The positive modulatory involvement of SORT retrieval events in left TPJ network recruitment is consistent with findings that this region is involved in semantic memory retrieval.
“The positive modulatory involvement of SORT retrieval events in this network recruitment is consistent with findings that this region is involved in semantic memory retrieval [Burianova et al., 2010].”
From Specific default mode subnetworks support mentalizing as revealed through opposing network recruitment by social and semantic FMRI tasks: Mentalizing and Default-Mode Subnetworks (2015) · cites this paper as Burianova et al., 2010
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Brain Activation Associated with Pride and Shame
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BOLD signal changes can oppose oxygen metabolism across the human cortex
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Competitive and cooperative interactions between medial temporal and striatal learning systems
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Anosognosia in patients with Alzheimer's disease: current perspectives
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Creativity in verbal associations is linked to semantic control
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- Authors
- Burianova, H., McIntosh, A. R., & Grady, C. L.
- Affiliations
- University of Toronto (CA)
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 49
- Issue
- 1
- Pages
- 865-874
- ISSN
- 1053-8119 (ISSN-L)
- OpenAlex
- W2166328167
- Cited by
- 283
- References
- 139
- Citations by year
- 2026: 9 · 2025: 7 · 2024: 17 · 2023: 19 · 2022: 9 · 2021: 36 · 2020: 16 · 2019: 18 · 2018: 21 · 2017: 15 · 2016: 16 · 2015: 16 · 2014: 14 · 2013: 15 · 2012: 21
- FWCI
- 8.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (MOP 14036)
- Canada Research Chairs program
- Ontario Research Fund
- Canadian Foundation for Innovation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- autobiographical memory, episodic memory, semantic memory, memory retrieval, functional connectivity, hippocampus, caudate nucleus, lingual gyrus, declarative memory, cingulate cortex, temporoparietal junction
- MeSH terms
- Adult, Brain, Brain Mapping, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Memory, Short-Term, Nerve Net, Photic Stimulation, Psychomotor Performance, Mental Recall, Young Adult
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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