Parenting and plasticity

Leuner, Benedetta; Glasper, Erica R.; Gould, Elizabeth

doi:10.1016/j.tins.2010.07.003

Cited by 159Neuroendocrine regulation and behaviorStress Responses and CortisolMaternal Mental Health During Pregnancy and Postpartum

Parenting and plasticity

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Leuner, Benedetta, Glasper, Erica R., Gould, Elizabeth·2010·Trends in Neurosciences

DOI 10.1016/j.tins.2010.07.003PMC PMC3076301

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Abstract

As any new parent knows, having a baby provides opportunities for enrichment, learning and stress - experiences known to change the adult brain. Yet surprisingly little is known about the effects of maternal experience, and even less about the effects of paternal experience, on neural circuitry not directly involved in parenting. Here we discuss how caregiving and the accompanying experiential and hormonal changes influence the hippocampus and prefrontal cortex, brain regions involved in cognition and mood regulation. A better understanding of how parenting impacts the brain is likely to help in devising strategies for treating parental depression, a condition that can have serious cognitive and mental health consequences for children.

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Animal evidence suggests mixed findings on reduced neurogenesis in the hippocampus but increased synaptic density in the prefrontal cortex during the postpartum period.
“animal evidence suggests mixed findings on reduced neurogenesis in the hippocampus but increased synaptic density in the prefrontal cortex during the postpartum period (Leuner et al., 2010).”
From The maternal brain and its plasticity in humans (2016) · cites this paper as Leuner et al., 2010

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Neurogenesis in the adult human hippocampus
Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369 · see citing works
More hippocampal neurons in adult mice living in an enriched environment
Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,513 · see citing works
The Infant's Response to Entrapment between Contradictory Messages in Face-to-Face Interaction
Tronick, E., Als, H., Adamson, L., Wise, S., & Brazelton, T. B. (1978) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)62273-1 · Cited by 1,880 · cited 1× · see citing works
“For example, babies become noticeably distressed when an adult (mother, father or unrelated caregiver) maintains a non-interactive still face [106,107].”
Neurocircuitry of Mood Disorders
Price, J. L., & Drevets, W. C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.104 · Cited by 1,606 · see citing works
Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
Cameron, H. A., & Mckay, R. D. G. (2001) · Journal of Comparative Neurology · doi:10.1002/cne.1040 · Cited by 1,585 · see citing works
Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
Gould, E., Woolley, C., Frankfurt, M., & McEwen, B. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-04-01286.1990 · Cited by 1,406 · see citing works
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
Dalley, J. W., Cardinal, R. N., & Robbins, T. W. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.006 · Cited by 1,329 · see citing works
Maternal care, hippocampal synaptogenesis and cognitive development in rats
Liu, D., Diorio, J., Day, J. C., Francis, D. D., & Meaney, M. J. (2000) · Nature Neuroscience · doi:10.1038/77702 · Cited by 1,195 · see citing works
Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons
Woolley, C. S., Gould, E., & McEwen, B. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90778-a · Cited by 1,020 · see citing works
Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
Cameron, H. A., & Gould, E. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90224-0 · Cited by 999 · see citing works
Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting
Liston, C., Miller, M. M., Goldwater, D. S., Radley, J. J., Rocher, A. B., Hof, P. R., Morrison, J. H., & McEwen, B. S. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1184-06.2006 · Cited by 968 · see citing works
Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Involvement of glucocorticoid secretion and excitatory amino acid receptors
Magarin˜os, A. M., & McEwen, B. S. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00259-l · Cited by 863 · see citing works
Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex
Radley, J. J., Rocher, A. B., Miller, M., Janssen, W. G. M., Liston, C., Hof, P. R., McEwen, B. S., & Morrison, J. H. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhi104 · Cited by 820 · see citing works
Paternal depression in the postnatal period and child development: a prospective population study
Ramchandani, P., Stein, A., Evans, J., & O'Connor, T. G. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66778-5 · Cited by 819 · see citing works
Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety
Adhikari, A., Topiwala, M. A., & Gordon, J. A. (2010) · Neuron · doi:10.1016/j.neuron.2009.12.002 · Cited by 729 · see citing works
Pregnancy-Stimulated Neurogenesis in the Adult Female Forebrain Mediated by Prolactin
Shingo, T., Gregg, C., Enwere, E. K., Fujikawa, H., Hassam, R., Geary, C. L., Cross, J. C., & Weiss, S. (2003) · Science · doi:10.1126/science.1076647 · Cited by 711 · see citing works
Individual and Combined Effects of Postpartum Depression in Mothers and Fathers on Parenting Behavior
Paulson, J. F., Dauber, S., & Leiferman, J. A. (2006) · Pediatrics · doi:10.1542/peds.2005-2948 · Cited by 706 · see citing works
Stress and adult neurogenesis
Mirescu, C., & Gould, E. (2006) · Hippocampus · doi:10.1002/hipo.20155 · Cited by 701 · see citing works
The Neurobiology of Parental Behavior
(2003) · Hormones, Brain, and Behavior · doi:10.1007/b97533 · Cited by 684 · see citing works
Environmental Enrichment Reverses the Effects of Maternal Separation on Stress Reactivity
Francis, D. D., Diorio, J., Plotsky, P. M., & Meaney, M. J. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-18-07840.2002 · Cited by 663 · see citing works
Paternal postpartum depression, its relationship to maternal postpartum depression, and implications for family health
Goodman, J. H. (2004) · Journal of Advanced Nursing · doi:10.1046/j.1365-2648.2003.02857.x · Cited by 660 · see citing works
Adrenal hormones suppress cell division in the adult rat dentate gyrus
Gould, E., Cameron, H. A., Daniels, D., Woolley, C. S., & McEwen, B. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-09-03642.1992 · Cited by 652 · see citing works
Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent–infant contact
Feldman, R., Gordon, I., Schneiderman, I., Weisman, O., & Zagoory-Sharon, O. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.01.013 · Cited by 638 · see citing works
Early life experience alters response of adult neurogenesis to stress
Mirescu, C., Peters, J. D., & Gould, E. (2004) · Nature Neuroscience · doi:10.1038/nn1290 · Cited by 625 · see citing works
Self-citation
Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
Wellman, C. L. (2001) · Journal of Neurobiology · doi:10.1002/neu.1079 · Cited by 594 · see citing works
Adult hippocampal neurogenesis is involved in anxiety-related behaviors
Revest, J.-M., Dupret, D., Koehl, M., Funk-Reiter, C., Grosjean, N., Piazza, P.-V., & Abrous, D. N. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.15 · Cited by 549 · see citing works
Is there a link between adult neurogenesis and learning?
Leuner, B., Gould, E., & Shors, T. J. (2006) · Hippocampus · doi:10.1002/hipo.20153 · Cited by 530 · see citing works
Experience-Specific Functional Modification of the Dentate Gyrus through Adult Neurogenesis: A Critical Period during an Immature Stage
Tashiro, A., Makino, H., & Gage, F. H. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4941-06.2007 · Cited by 521 · see citing works
Postpartum Depression: What We Know
O'Hara, M. W. (2009) · Journal of Clinical Psychology · doi:10.1002/jclp.20644 · Cited by 500 · see citing works
Brain basis of early parent–infant interactions: psychology, physiology, and <i>in vivo</i> functional neuroimaging studies
Swain, J. E., Lorberbaum, J. P., Kose, S., & Strathearn, L. (2007) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2007.01731.x · Cited by 499 · see citing works
What’s in a smile? Maternal brain responses to infant facial cues
Strathearn, L., Li, J., Fonagy, P., & Montague, P. R. (2008) · Pediatrics · doi:10.1542/peds.2007-1566 · Cited by 460 · see citing works
LTP varies across the estrous cycle: enhanced synaptic plasticity in proestrus rats.
Warren, S. G., Humphreys, A. G., Juraska, J., & Greenough, W. (1995) · Brain Research · doi:10.1016/0006-8993(95)01059-9 · Cited by 457 · see citing works
Structural Plasticity and Hippocampal Function
Leuner, B., & Gould, E. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.093008.100359 · Cited by 452 · see citing works
The still-face: A history of a shared experimental paradigm
Adamson, L. B., & Frick, J. E. (2003) · Infancy · doi:10.1207/s15327078in0404_01 · Cited by 449 · see citing works
GABAAR Plasticity during Pregnancy: Relevance to Postpartum Depression
Maguire, J., & Mody, I. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.019 · Cited by 437 · see citing works
Maternal depression and psychiatric outcomes in adolescent offspring: A 13-year longitudinal study
Halligan, S. L., Murray, L., Martins, C., & Cooper, P. J. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.06.010 · Cited by 421 · see citing works
The expectant brain: adapting for motherhood
Brunton, P. J., & Russell, J. A. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2280 · Cited by 407 · see citing works
Testosterone and prolactin are associated with emotional responses to infant cries in new fathers
Fleming, A. S., Corter, C., Stallings, J., & Steiner, M. (2002) · Hormones and Behavior · doi:10.1006/hbeh.2002.1840 · Cited by 401 · see citing works
Differential sex-independent amygdala response to infant crying and laughing in parents versus nonparents
Seifritz, E., Esposito, F., Neuhoff, J. G., Lüthi, A., Mustovic, H., Dammann, G., von Bardeleben, U., Radue, E. W., Cirillo, S., Tedeschi, G., et al. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00697-8 · Cited by 373 · see citing works
Oxytocin improves long-lasting spatial memory during motherhood through MAP kinase cascade
Tomizawa, K., Iga, N., Lü, Y.-F., Moriwaki, A., Matsushita, M., Li, S., Miyamoto, O., Itano, T., & Matsui, H. (2003) · Nature Neuroscience · doi:10.1038/nn1023 · Cited by 372 · see citing works
Motherhood improves learning and memory
Kinsley, C. H., Madonia, L., Gifford, G. W., Tureski, K., Griffin, G. R., Lowry, C., Williams, J., Collins, J., McLearie, H., & Lambert, K. G. (1999) · Nature · doi:10.1038/45957 · Cited by 297 · see citing works
Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose‐ and time‐dependent manner
Tanapat, P., Hastings, N. B., & Gould, E. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20385 · Cited by 270 · see citing works
Antepartum and postpartum exposure to maternal depression: different effects on different adolescent outcomes
Hay, D. F., Pawlby, S. J., Waters, C. S., & Sharp, D. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01959.x · Cited by 270 · see citing works
Early parental depression and child language development
Paulson, J. F., Keefe, H. A., & Leiferman, J. A. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01973.x · Cited by 267 · see citing works
Estrogen Alters Spine Number and Morphology in Prefrontal Cortex of Aged Female Rhesus Monkeys
Hao, J., Rapp, P. R., Leffler, A. E., Leffler, S. R., Janssen, W. G. M., Lou, W. Y. W., McKay, H. M., Roberts, J. A., Wearne, S. L., Hof, P. R., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3440-05.2006 · Cited by 257 · see citing works
Ovariectomized rats show decreased recognition memory and spine density in the hippocampus and prefrontal cortex
Wallace, M. E., Luine, V. N., Arellanos, A., & Frankfurt, M. (2006) · Brain Research · doi:10.1016/j.brainres.2006.07.064 · Cited by 255 · see citing works
Partial reversal of the effect of maternal care on cognitive function through environmental enrichment
Bredy, T. W., Humpartzoomian, R., Cain, D. P., & Meaney, M. J. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00918-1 · Cited by 248 · see citing works
Hormonal Changes in Males of a Naturally Biparental and a Uniparental Mammal
Wheaton, C. J., & Wynne‐Edwards, K. E. (1999) · Hormones and Behavior · doi:10.1006/hbeh.1998.1509 · Cited by 245 · see citing works
Testosterone promotes paternal behaviour in a monogamous mammal via conversion to oestrogen
Trainor, B. C., & Marler, C. A. (2002) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2001.1954 · Cited by 238 · see citing works
Motherhood and the hormones of pregnancy modify concentrations of hippocampal neuronal dendritic spines
Kinsley, C. H., Trainer, R., Stafisso-Sandoz, G., Quadros, P. S., Keyser‐Marcus, L., Hearon, C., Meyer, E. A. A., Hester, N. W., Morgan, M. D., & Kozub, F. J. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.05.017 · Cited by 233 · see citing works
Change in brain size during and after pregnancy: study in healthy women and women with preeclampsia.
Oatridge, A., Holdcroft, A., Saeed, N., Hajnal, J. V., Puri, B. K., Fusi, L., & Bydder, G. M. (2002) · PubMed Central · Cited by 232 · see citing works
The biology of paternal care in human and nonhuman primates
Fernandez-Duque, E., Valeggia, C. R., & Mendoza, S. P. (2009) · Annual Review of Anthropology · doi:10.1146/annurev-anthro-091908-164334 · Cited by 232 · see citing works
Striking Variations in Corticosteroid Modulation of Long-Term Potentiation along the Septotemporal Axis of the Hippocampus
Maggio, N., & Segal, M. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0155-07.2007 · Cited by 230 · see citing works
Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus
Banasr, M., Héry, M., Brezun, J. M., & Daszuta, A. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01763.x · Cited by 226 · see citing works
Sex differences in the parental behavior of rodents
Lonstein, J. S., & De Vries, G. J. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00036-1 · Cited by 226 · see citing works
Reproductive experience alters hippocampal neurogenesis during the postpartum period in the dam
Pawluski, J. L., & Galea, L. A. M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.07.031 · Cited by 209 · see citing works
Maternal care influences neuronal survival in the hippocampus of the rat
Bredy, T. W., Grant, R. J., Champagne, D. L., & Meaney, M. J. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.02965.x · Cited by 208 · see citing works
Experience induces structural and biochemical changes in the adult primate brain
Kozorovitskiy, Y., Gross, C. G., Kopil, C., Battaglia, L., McBreen, M., Stranahan, A. M., & Gould, E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508817102 · Cited by 202 · see citing works
Paternal recognition of adult offspring mediated by newly generated CNS neurons
Mak, G. K., & Weiss, S. (2010) · Nature Neuroscience · doi:10.1038/nn.2550 · Cited by 201 · see citing works
Functional Magnetic Resonance Imaging Shows Oxytocin Activates Brain Regions Associated with Mother–Pup Bonding during Suckling
Febo, M., Numan, M., & Ferris, C. F. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3604-05.2005 · Cited by 197 · see citing works
The influence of maternal depression, caregiving, and socioeconomic status in the post‐natal year on children's language development
Stein, A., Malmberg, L. ‐., Sylva, K., Barnes, J., Leach, P., & the FCCC team (2008) · Child: Care, Health and Development · doi:10.1111/j.1365-2214.2008.00837.x · Cited by 195 · see citing works
Foster litters prevent hypothalamic-pituitary-adrenal axis sensitization mediated by neonatal maternal separation
Huot, R. L., Gonzalez, M. E., Ladd, C. O., Thrivikraman, K. V., & Plotsky, P. M. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00028-3 · Cited by 191 · see citing works
Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response
Schloesser, R. J., Manji, H. K., & Martinowich, K. (2009) · Neuroreport · doi:10.1097/wnr.0b013e3283293e59 · Cited by 187 · see citing works
Maternal experience inhibits the production of immature neurons in the hippocampus during the postpartum period through elevations in adrenal steroids
Leuner, B., Mirescu, C., Noiman, L., & Gould, E. (2007) · Hippocampus · doi:10.1002/hipo.20278 · Cited by 174 · see citing works
Hormonal Changes in Mammalian Fathers
Wynne‐Edwards, K. E. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1699 · Cited by 173 · see citing works
Hippocampal morphology is differentially affected by reproductive experience in the mother
Pawluski, J. L., & Galea, L. A. M. (2005) · Journal of Neurobiology · doi:10.1002/neu.20194 · Cited by 172 · see citing works
Changes in anxiety and cognition due to reproductive experience: A review of data from rodent and human mothers
Macbeth, A. H., & Luine, V. N. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.08.011 · Cited by 169 · see citing works
Limbic system fos expression associated with paternal behavior
Kirkpatrick, B. W., Kim, J. W., & Insel, T. R. (1994) · Brain Research · doi:10.1016/s0006-8993(09)90016-6 · Cited by 165 · see citing works
Influence of sex, estrous cycle and motherhood on dendritic spine density in the rat medial amygdala revealed by the Golgi method
Rasia‐Filho, A. A., Fabian, C., Rigoti, K. M., & Achaval, M. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.04.009 · Cited by 164 · see citing works
Paternal care in rodents: Weakening support for hormonal regulation of the transition to behavioral fatherhood in rodent animal models of biparental care
Wynne‐Edwards, K. E., & Timonin, M. E. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.03.018 · Cited by 163 · see citing works
Fatherhood affects dendritic spines and vasopressin V1a receptors in the primate prefrontal cortex
Kozorovitskiy, Y., Hughes, M., Lee, K., & Gould, E. (2006) · Nature Neuroscience · doi:10.1038/nn1753 · Cited by 158 · see citing works
Self-citation
Motherhood mitigates aging-related decrements in learning and memory and positively affects brain aging in the rat
Gatewood, J. D., Morgan, M. D., Eaton, M., McNamara, I. M., Stevens, L. F., Macbeth, A. H., Meyer, E. A. A., Lomas, L. M., Kozub, F. J., Lambert, K. G., et al. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.03.016 · Cited by 155 · see citing works
Medial prefrontal cortex lesions in the female rat affect sexual and maternal behavior and their sequential organization.
Afonso, V. M., Sison, M., Lovic, V., & Fleming, A. S. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.3.515 · Cited by 152 · see citing works
Reproductive experience differentially affects spatial reference and working memory performance in the mother
Pawluski, J. L., Walker, S. K., & Galea, L. A. M. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.05.016 · Cited by 150 · see citing works
Bringing birth-related paternal depression to the fore
Schumacher, M. V., Zúbaran, C., & White, G. (2008) · Women and Birth · doi:10.1016/j.wombi.2008.03.008 · Cited by 148 · see citing works
Spatial Working Memory and Hippocampal Size across Pregnancy in Rats
Galea, L. A. M., Ormerod, B. K., Sampath, S., Kostaras, X., Wilkie, D. M., & Phelps, M. T. (2000) · Hormones and Behavior · doi:10.1006/hbeh.1999.1560 · Cited by 140 · see citing works
The impact of postnatal and concurrent maternal depression on child behaviour during the early school years
Fihrer, I., McMahon, C. A., & Taylor, A. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.03.001 · Cited by 137 · see citing works
Plasticity in the maternal circuit: Effects of maternal experience on Fos-Lir in hypothalamic, limbic, and cortical structures in the postpartum rat.
Fleming, A. S., & Korsmit, M. (1996) · Behavioral Neuroscience · doi:10.1037//0735-7044.110.3.567 · Cited by 136 · see citing works
Hypothalamic Vasopressin Gene Expression Increases in Both Males and Females Postpartum in a Biparental Rodent
Wang, Z., Liu, Y., Young, L. J., & Insel, T. R. (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00435.x · Cited by 134 · see citing works
Comparison of medial preoptic, amygdala, and nucleus accumbens lesions on parental behavior in California mice (Peromyscus californicus)
Lee, A. W., & Brown, R. E. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.05.008 · Cited by 128 · see citing works
Early motherhood in rats is associated with a modification of hippocampal function
Darnaudéry, M., Perez-Martin, M., Del Favero, F., Gomez-Roldan, C., Garcia-Segura, L. M., & Maccari, S. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.05.012 · Cited by 128 · see citing works
First reproductive experience persistently affects spatial reference and working memory in the mother and these effects are not due to pregnancy or ‘mothering’ alone
Pawluski, J. L., Vanderbyl, B. L., Ragan, K., & Galea, L. A. M. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.017 · Cited by 127 · see citing works
Olfactory mediation of maternal behavior in selected mammalian species
Lévy, F., & Keller, M. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.12.017 · Cited by 124 · see citing works
From here to paternity: Neural correlates of the onset of paternal behavior in California mice (Peromyscus californicus)
A, T. R. D. J., Miyetani Chauke, A., Harris, B. N., & Wendy Saltzman, A. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.05.001 · Cited by 123 · see citing works
Hippocampal lesions disrupt maternal, not sexual, behavior in the albino rat.
Kimble, D. P., Rogers, L., & Hendrickson, C. W. (1967) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0024605 · Cited by 119 · see citing works
Hormonal Responses of Male Gerbils to Stimuli from Their Mate and Pups
Brown, R. E., Murdoch, T., Murphy, P. R., & Moger, W. H. (1995) · Hormones and Behavior · doi:10.1006/hbeh.1995.1275 · Cited by 115 · see citing works
Alterations of medial preoptic area neurons following pregnancy and pregnancy-like steroidal treatment in the rat
Keyser‐Marcus, L., Stafisso-Sandoz, G., Gerecke, K. M., Jasnow, A. M., Nightingale, L., Lambert, K. G., Gatewood, J. D., & Kinsley, C. H. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00554-8 · Cited by 115 · see citing works
Gestation-induced cell proliferation in the rat brain
Furuta, M., & Bridges, R. S. (2005) · Developmental Brain Research · doi:10.1016/j.devbrainres.2005.01.008 · Cited by 111 · see citing works
Plasticity in the maternal circuit: Effects of maternal experience on Fos-Lir in hypothalamic, limbic, and cortical structures in the postpartum rat.
Fleming, A. S., & Korsmit, M. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.3.567 · Cited by 111 · see citing works
Adult hippocampal cell proliferation is suppressed with estrogen withdrawal after a hormone-simulated pregnancy
Green, A. D., & Galea, L. A. M. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2008.02.023 · Cited by 109 · see citing works
Dendritic Growth in Medial Prefrontal Cortex and Cognitive Flexibility Are Enhanced during the Postpartum Period
Leuner, B., & Gould, E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3388-10.2010 · Cited by 105 · see citing works
Daily injections alter spine density in rat medial prefrontal cortex
Seib, L. M., & Wellman, C. L. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(02)01287-9 · Cited by 100 · see citing works
Paternal deprivation during infancy results in dendrite- and time-specific changes of dendritic development and spine formation in the orbitofrontal cortex of the biparental rodent Octodon degus
Helmeke, C., Seidel, K., Poeggel, G., Bredy, T. W., Abraham, A., & Braun, K. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.07.008 · Cited by 98 · see citing works
Motherhood alters the cellular response to estrogens in the hippocampus later in life
Barha, C. K., & Galea, L. A. M. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.12.004 · Cited by 92 · see citing works
Motherhood‐induced memory improvement persists across lifespan in rats but is abolished by a gestational stress
Lemaire, V., Billard, J., Dutar, P., George, O., Piazza, P. V., Epelbaum, J., Moal, M. L., & Mayo, W. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04870.x · Cited by 90 · see citing works
Changes in Expression and Function of Extrasynaptic GABAAReceptors in the Rat Hippocampus during Pregnancy and after Delivery
Sanna, E., Mostallino, M. C., Murru, L., Carta, M., Talani, G., Zucca, S., Mura, M. L., Maciocco, E., & Biggio, G. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3684-08.2009 · Cited by 88 · see citing works
Effects of multiparity on recognition memory, monoaminergic neurotransmitters, and brain-derived neurotrophic factor (BDNF)
Macbeth, A. H., Scharfman, H. E., MacLusky, N. J., Gautreaux, C., & Luine, V. N. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.08.011 · Cited by 88 · see citing works
Paternal behavior is associated with central neurohormone receptor binding patterns in meadow voles (Microtus pennsylvanicus).
Parker, K. J., Kinney, L. F., Phillips, K. M., & Lee, T. M. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.6.1341 · Cited by 82 · see citing works
Plasticity in the maternal circuit: Effects of experience and partum condition on brain astroctye number in female rats.
Featherstone, R. E., Fleming, A. S., & Ivy, G. O. (2000) · Behavioral Neuroscience · doi:10.1037//0735-7044.114.1.158 · Cited by 74 · see citing works
Decrease in hippocampal neurogenesis during pregnancy: a link to immunity
Rolls, A., Schori, H., London, A., & Schwartz, M. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002126 · Cited by 69 · see citing works
Lack of paternal care affects synaptic development in the anterior cingulate cortex
Ovtscharoff, W. A., Helmeke, C., & Braun, K. (2006) · Brain Research · doi:10.1016/j.brainres.2006.07.106 · Cited by 68 · see citing works
Effects of dopamine receptor antagonism with haloperidol on nurturing behavior in the biparental prairie vole
Lonstein, J. S. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00952-8 · Cited by 68 · see citing works
Pregnant rats show enhanced spatial memory, decreased anxiety, and altered levels of monoaminergic neurotransmitters
Macbeth, A. H., Gautreaux, C., & Luine, V. N. (2008) · Brain Research · doi:10.1016/j.brainres.2008.09.006 · Cited by 67 · see citing works
Plasticity in the maternal circuit: Effects of experience and partum condition on brain astroctye number in female rats.
Featherstone, R. E., Fleming, A. S., & Ivy, G. O. (2000) · Behavioral Neuroscience · doi:10.1037/0735-7044.114.1.158 · Cited by 67 · see citing works
Enhanced maternal aggression and associated changes in neuropeptide gene expression in multiparous rats.
Nephew, B. C., Bridges, R. S., Lovelock, D. F., & Byrnes, E. M. (2009) · Behavioral Neuroscience · doi:10.1037/a0016734 · Cited by 64 · see citing works
Pup exposure elicits hippocampal cell proliferation in the prairie vole
Ruscio, M. G., Sweeny, T. D., Hazelton, J. L., Suppatkul, P., Boothe, E., & Carter, C. S. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.08.028 · Cited by 62 · see citing works
Pregnancy Decreases Oestrogen Receptor α Expression and Pyknosis, but not Cell Proliferation or Survival, in the Hippocampus
Pawluski, J. L., Barakauskas, V., & Galea, L. A. M. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01960.x · Cited by 57 · see citing works
Stress‐induced synaptic changes in the rat anterior cingulate cortex are dependent on endocrine developmental time windows
Gos, T., Bock, J., Poeggel, G., & Braun, K. (2007) · Synapse · doi:10.1002/syn.20477 · Cited by 55 · see citing works
Plasma hormonal profiles and dendritic spine density and morphology in the hippocampal CA1 stratum radiatum, evidenced by light microscopy, of virgin and postpartum female rats
Brusco, J., Wittmann, R., de Azevedo, M. S., Lucion, A. B., Franci, C. R., Giovenardi, M., & Rasia‐Filho, A. A. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.063 · Cited by 54 · see citing works
Effects of fimbria lesions on maternal behavior in the rat☆
Terlecki, L. J., & Sainsbury, R. (1978) · Physiology & Behavior · doi:10.1016/0031-9384(78)90281-0 · Cited by 51 · see citing works
Two-month-old infants of depressed mothers show mild, delayed and persistent change in emotional state after non-contingent interaction
Nadel, J., Soussignan, R., Canet, P., Libert, G., & Gérardin, P. (2005) · Infant Behavior and Development · doi:10.1016/j.infbeh.2005.03.005 · Cited by 47 · see citing works
Interventions with depressed mothers and their infants: Modifying interactive behaviours
Jung, V., Short, R. H., Letourneau, N. L., & Andrews, D. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.07.014 · Cited by 45 · see citing works
Effect of resource availability on biparental care, and offspring neural and behavioral development in the California mouse (Peromyscus californicus)
Bredy, T. W., Brown, R. E., & Meaney, M. J. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05266.x · Cited by 44 · see citing works
Effects of maternal behavior induction and pup exposure on neurogenesis in adult, virgin female rats
Furuta, M., & Bridges, R. S. (2009) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2009.08.011 · Cited by 44 · see citing works
Electrical activity of prefrontal cortex and ventral tegmental area during rat maternal behavior
Hernández-González, M., Navarro-Meza, M., Prieto-Beracoechea, C. A., & Guevara, M. Á. (2005) · Behavioural Processes · doi:10.1016/j.beproc.2005.06.002 · Cited by 40 · see citing works
The effects of adrenalectomy and corticosterone replacement on induction of maternal behavior in the virgin female rat
Rees, S. L., Panesar, S., Steiner, M. S., & Fleming, A. S. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.08.012 · Cited by 35 · see citing works
Steroid hormones and maternal experience interact to induce glial plasticity in the cingulate cortex
Salmaso, N., Nadeau, J. R., & Woodside, B. C. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06627.x · Cited by 33 · see citing works
Alterations in GABAA Receptor α2 Subunit mRNA Expression following Reproductive Experience in Rats
Byrnes, E. M., Lee, J. O., & Bridges, R. S. (2007) · Neuroendocrinology · doi:10.1159/000102535 · Cited by 22 · see citing works
Morphological plasticity in the maternal brain: Comment on Kinsley et al.; motherhood and the hormones of pregnancy modify concentrations of hippocampal neuronal dendritic spines
Woodside, B. C. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.09.001 · Cited by 10 · see citing works

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[32]Kozorovitskiy Y 2007 Fatherhood influences neurogenesis in the hippocampus of California mice Proceedings of the 2007 Neuroscience Meeting, Abstract 626.21, Society for Neuroscience

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Opendak, M. M., Briones, B. A., & Gould, E. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2016.02.002 · Cited by 35 · see citing works
Fatherhood contributes to increased hippocampal spine density and anxiety regulation in California mice
Glasper, E. R., Hyer, M. M., Katakam, J., Harper, R., Ameri, C., & Wolz, T. (2015) · Brain and Behavior · doi:10.1002/brb3.416 · Cited by 33 · see citing works
Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam
Gemmel, M., Harmeyer, D., Bögi, E., Fillet, M., Hill, L. A., Hammond, G. L., Charlier, T. D., & Pawluski, J. L. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.11.038 · Cited by 33 · see citing works
Beneficial intergenerational effects of exercise on brain and cognition: a multilevel meta‐analysis of mean and variance
Yang, Y.-F., Lagisz, M., Foo, Y., Noble, D., Anwer, H., & Nakagawa, S. (2021) · Biological Reviews of The Cambridge Philosophical Society · doi:10.1111/brv.12712 · Cited by 29 · see citing works
Neurogenesis and anxiety-like behavior in male California mice during the mate’s postpartum period
Hyer, M. M., Hunter, T. J., Katakam, J., Wolz, T., & Glasper, E. R. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13168 · Cited by 32 · see citing works
Sexual Dimorphism of Parental Care: From Genes to Behavior
Zilkha, N., Scott, N., & Kimchi, T. (2017) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-072116-031447 · Cited by 32 · see citing works
Hypothalamic Control of Prolactin Secretion, and the Multiple Reproductive Functions of Prolactin
Grattan, D. R., & Tissier, P. L. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00012-0 · Cited by 31 · see citing works
Structural and Functional Plasticity in the Maternal Brain Circuitry
Pereira, M. (2016) · New Directions for Child and Adolescent Development · doi:10.1002/cad.20163 · Cited by 30 · see citing works
Dissecting maternal care: Patterns of maternal parenting in a prospective cohort study
Unternäehrer, E., Cost, K. T., Bouvette–Turcot, A., Gaudreau, H., Massicotte, R., Dhir, S. K., Dass, S. A. H., O’Donnell, K. J., Green, C. G., Atkinson, L. R., et al. (2019) · Journal of Neuroendocrinology · doi:10.1111/jne.12784 · Cited by 27 · see citing works
Effect of sertraline on central serotonin and hippocampal plasticity in pregnant and non-pregnant rats
Pawluski, J. L., Paravatou, R., Even, A., Cobraiville, G., Fillet, M., Kokras, N., Dalla, C., & Charlier, T. D. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.107950 · Cited by 26 · see citing works
Pairmate-dependent pup retrieval as parental behavior in male mice
Liang, M., Zhong, J., Liu, H.-X., Lopatina, O., Nakada, R., Yamauchi, A.-M., & Higashida, H. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00186 · Cited by 25 · see citing works
Baby cry recognition is independent of motherhood but improved by experience and exposure
Bouchet, H., Plat, A., Levréro, F., Reby, D., Patural, H., & Mathevon, N. (2020) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2019.2499 · Cited by 24 · see citing works
Maternal separation: Does it hold the potential to model consequences of postpartum depression?
Mundorf, A., Bölükbas, I., & Freund, N. (2022) · Developmental Psychobiology · doi:10.1002/dev.22219 · Cited by 23 · see citing works
Regulatory role of prolactin in paternal behavior in male parents
Hashemian, F., Shafigh, F., & Roohi, E. (2016) · Journal of Postgraduate Medicine · doi:10.4103/0022-3859.186389 · Cited by 22 · see citing works
Long-term association of pregnancy and maternal brain structure: the Rotterdam Study
Aleknavičiūtė, J., Evans, T. E., Aribas, E., de Vries, M. W., Steegers, E. A. P., Ikram, M. A., Tiemeier, H. W., Kavousi, M., Vernooij, M. W., & Kushner, S. A. (2022) · European Journal of Epidemiology · doi:10.1007/s10654-021-00818-5 · Cited by 25 · see citing works
Cellular and molecular signatures of motherhood in the adult and ageing rat brain
Duarte‐Guterman, P., Richard, J. E., Lieblich, S. E., Eid, R. S., Lamers, Y., & Galea, L. A. M. (2023) · Open Biology · doi:10.1098/rsob.230217 · Cited by 21 · see citing works
Estrogen-dependent modifications to hippocampal plasticity in paternal California mice (Peromyscus californicus)
Hyer, M. M., Khantsis, S., Venezia, A. C., Madison, F. N., Hallgarth, L. A., Adekola, E., & Glasper, E. R. (2017) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.09.015 · Cited by 20 · see citing works
Not all “caregivers” are created equal: Liking, caring and facial expression responses to the baby schema as a function of parenthood and testosterone
Löwenbrück, F., & Heß, U. (2021) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108120 · Cited by 21 · see citing works
Involvement of the dopamine system in paternal behavior induced by repeated pup exposure in virgin male ICR mice
Cai, W., Ma, H., Xun, Y., Hou, W., Wang, L., Zhang, X., Ran, Y., Yuan, W., Guo, Q., Zhang, J., et al. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113519 · Cited by 15 · see citing works
Is Depression Associated with Contraceptive Motivations, Intentions, and Use Among a Sample of Low-Income Latinas?
Carvajal, D. N., Ghazarian, S. R., Crowne, S. S., Brown, P. B., Carter‐Pokras, O., DUGGAN, A. K., & Barnet, B. (2014) · Women s Health Issues · doi:10.1016/j.whi.2013.10.003 · Cited by 15 · see citing works
Adult Neurogenesis, Chronic Stress and Depression
Lucassen, P. J., Oomen, C. A., Schouten, M., Encinas, J. M., & Fitzsimons, C. P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801977-1.00008-8 · Cited by 15 · see citing works
Differential Effect of Caffeine Consumption on Diverse Brain Areas of Pregnant Rats
Ballesteros‐Yáñez, I., Castillo, C. A., Amo‐Salas, M., Albasanz, J. L., & Martı́n, M. (2012) · Journal of Caffeine Research · doi:10.1089/jcr.2012.0011 · Cited by 15 · see citing works
Adult mammalian neurogenesis and motivated behaviors
Jorgensen, C. (2018) · Integrative Zoology · doi:10.1111/1749-4877.12335 · Cited by 15 · see citing works
Gender-related dimensions of childhood adversities in the general population
Coêlho, B. M., Santana, G. L., Viana, M. C., Andrade, L. H., & Wang, Y. (2018) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2017-2366 · Cited by 15 · see citing works
Reproductive experience modified dendritic spines on cortical pyramidal neurons to enhance sensory perception and spatial learning in rats
Chen, J.-R., Lim, S. H., Chung, S.-C., Lee, Y.-F., Wang, Y.-J., Tseng, G.-F., & Wang, T.-J. (2017) · Experimental Animals · doi:10.1538/expanim.16-0061 · Cited by 14 · see citing works
Effects of pairing on color change and central gene expression in lined seahorses
Mederos, S. L., Duarte, R. C., Mastoras, M., Dennis, M. Y., Settles, M. L., Lau, A. R., Scott, A. M., Woodward, K., Johnson, C., Seelke, A. M. H., et al. (2022) · Genes Brain & Behavior · doi:10.1111/gbb.12812 · Cited by 14 · see citing works
Parity modifies endocrine hormones in urine and problem-solving strategies of captive owl monkeys (Aotus spp.).
Bardi, M., Eckles, M., Kirk, E., Landis, T., Evans, S., & Lambert, K. G. (2014) · PubMed Central · Cited by 14 · see citing works
Separation increases passive stress-coping behaviors during forced swim and alters hippocampal dendritic morphology in California mice
Hyer, M. M., & Glasper, E. R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175713 · Cited by 13 · see citing works
Reproductive experience alters the involvement of N-methyl-D-aspartate receptors in fear extinction, but not fear conditioning, in female Sprague Dawley rats
Tang, S., & Graham, B. M. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4956-y · Cited by 13 · see citing works
Investigating the effects of perinatal status and gender on adults’ responses to infant and adult facial emotion.
Parsons, C. E., Nummenmaa, L., Sinervä, E., Korja, R., Kajanoja, J., Young, K. S., Karlsson, H., & Karlsson, L. (2019) · Emotion · doi:10.1037/emo0000698 · Cited by 13 · see citing works
Social isolation increases cell proliferation in male and cell survival in female California mice (Peromyscus californicus)
Ruscio, M. G., King, S. B., & Haun, H. L. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.08.039 · Cited by 12 · see citing works
Frank Beach Award Winner: Lessons from poison frogs on ecological drivers of behavioral diversification
O’Connell, L. A. (2020) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104869 · Cited by 11 · see citing works
Listening to a baby crying induces higher electroencephalographic synchronization among prefrontal, temporal and parietal cortices in adoptive mothers
Hernández, M. P., Hernández-González, M., Aguirre, R. M. H., Amezcua-Gutiérrez, C., & Guevara, M. Á. (2017) · Infant Behavior and Development · doi:10.1016/j.infbeh.2017.02.003 · Cited by 10 · see citing works

Structural and Functional Plasticity in the Maternal Brain Circuitry
Pereira, M. (2016) · New Directions for Child and Adolescent Development · doi:10.1002/cad.20163 · Cited by 30 · see citing works
Sex differences and parental experience contribute to hippocampal remodelling across the lifespan
Duarte‐Guterman, P., & Zugno-Gadea, N. (2023) · Current Opinion in Physiology · doi:10.1016/j.cophys.2023.100703 · Cited by 1 · see citing works
The Role of Reproductive Experience on Hippocampal Function and Plasticity
Pawluski, J. L., & Galea, L. A. M. (2008) · Elsevier eBooks · doi:10.1016/b978-012374285-8.00032-9 · Cited by 10 · see citing works
Cognition and Neuroplasticity During Pregnancy and Postpartum
Blankers, S. A., Go, K. A., Surtees, D. C., Splinter, T. F. L., & Galea, L. A. M. (2024) · Masterclass in neuroendocrinology · doi:10.1007/978-3-031-51138-7_9 · Cited by 3 · see citing works
Mothering without smothering
Welberg, L. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2449

Authors: Leuner, B., Glasper, E. R., & Gould, E.
Affiliations: Princeton University (US)
Corresponding author: Gould, Elizabeth
ORCID: Leuner, Benedetta
Glasper, Erica R.
Gould, Elizabeth
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 2010-10
Volume: 33
Issue: 10
Pages: 465-473
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/j.tins.2010.07.003
PMC: PMC3076301
OpenAlex: W2102804349
Cited by: 159
References: 117
Citations by year: 2026: 6 · 2025: 7 · 2024: 9 · 2023: 10 · 2022: 11 · 2021: 9 · 2020: 7 · 2019: 16 · 2018: 9 · 2017: 12 · 2016: 19 · 2015: 15 · 2014: 14 · 2013: 5 · 2012: 6
FWCI: 0.59
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (5r01mh054970-03)
National Institute on Aging (F32AG033461)
National Institute of Mental Health (R01MH059740, MH084148, MH-54970, R00MH084148, K99MH084148)
Topics: Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords: parenting, neuroplasticity, maternal experience, fathers' experiences, caregiving, hippocampus, prefrontal cortex, parental depression, mood regulation, cognitive development, neuroendocrine changes
MeSH terms: Adult, Affect, Brain, Cognition, Depression, Hippocampus, Hormones, Humans, Parents, Stress, Psychological, Parenting, Prefrontal Cortex

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