Regulation of adult neurogenesis and plasticity by (early) stress, glucocorticoids, and inflammation.

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Polazzi, E., Mengoni, I., Caprini, M., Peña‐Altamira, E., Kurtys, E., & Monti, B. (2012) · Neurosignals · doi:10.1159/000337115 · Cited by 9,023 · see citing works

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,501 · see citing works

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395 · see citing works

Stress and the brain: from adaptation to disease

de Kloet, E. R., Joëls, M., & Holsboer, F. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1683 · Cited by 4,621 · see citing works

Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs

Rhen, T., & Cidlowski, J. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050541 · Cited by 3,149 · see citing works

Mechanisms and Functional Implications of Adult Neurogenesis

Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007 · see citing works

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426 · see citing works

The link between childhood trauma and depression: insights from HPA axis studies in humans

Heim, C., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.008 · Cited by 1,704 · see citing works

Stress revisited: a critical evaluation of the stress concept

Koolhaas, J. M., Bartolomucci, A., Buwalda, B., de Boer, S. F., Flügge, G., Korte, S. M., Meerlo, P., Murison, R., Olivier, B., Palanza, P., et al. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.02.003 · Cited by 1,626 · see citing works

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

Sierra, A., Encinas, J. M., Deudero, J. J. P., Chancey, J. H., Enikolopov, G., Overstreet-Wadiche, L. S., Tsirka, S. E., & Maletic-Savatic, M. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.08.014 · Cited by 1,622 · see citing works

The neuro-symphony of stress

Joëls, M., & Baram, T. Z. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2632 · Cited by 1,521 · see citing works

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

Gould, E., McEwen, B. S., Tanapat, P., Galea, L. A. M., & Fuchs, E. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02492.1997 · Cited by 1,496 · see citing works

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

Snyder, J. S., Soumier, A., Brewer, M., Pickel, J., & Cameron, H. A. (2011) · Nature · doi:10.1038/nature10287 · Cited by 1,473 · see citing works

Adult hippocampal neurogenesis in depression

Sahay, A., & Hen, R. (2007) · Nature Neuroscience · doi:10.1038/nn1969 · Cited by 1,206 · see citing works

Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1

Berkenbosch, F., van Oers, J., del Rey, A., Tilders, F., & Besedovsky, H. (1987) · Science · doi:10.1126/science.2443979 · Cited by 1,151 · see citing works

Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging

Sapolsky, R., Krey, L., & McEwen, B. (1985) · The Journal of Neuroscience · doi:10.1523/jneurosci.05-05-01222.1985 · Cited by 1,129 · see citing works

Hippocampal damage associated with prolonged glucocorticoid exposure in primates

Sapolsky, R., Uno, H., Rebert, C., & Finch, C. (1990) · The Journal of Neuroscience · doi:10.1523/jneurosci.10-09-02897.1990 · Cited by 1,103 · see citing works

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

Czéh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., van Kampen, M., Bartolomucci, A., & Fuchs, E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211427898 · Cited by 1,090 · see citing works

Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus

Lemaire, V., Koehl, M., Le Moal, M., & Abrous, D. N. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.20.11032 · Cited by 1,044 · see citing works

The cognitive activation theory of stress.

Ursin, H., & Eriksen, H. R. (2004) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00091-x · Cited by 1,004 · see citing works

The stress system in the human brain in depression and neurodegeneration

Swaab, D. F., Bao, A.-M., & Lucassen, P. J. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.03.003 · Cited by 984 · see citing works

Adult neurogenesis: from precursors to network and physiology

Abrous, D. N., Koehl, M., & Le Moal, M. (2005) · Physiological Reviews · doi:10.1152/physrev.00055.2003 · Cited by 971 · see citing works

Adult brain neurogenesis and psychiatry: a novel theory of depression

Jacobs, B. L., van Praag, H., & Gage, F. H. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000712 · Cited by 964 · see citing works

A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain

Ge, S., Yang, C.-H., Hsu, K.-S., Ming, G.-L., & Song, H. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.002 · Cited by 927 · see citing works

Microglia activated by IL-4 or IFN-γ differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells

Butovsky, O., Ziv, Y., Schwartz, A., Landa, G., Talpalar, A. E., Pluchino, S., Martino, G., & Schwartz, M. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.10.006 · Cited by 923 · see citing works

IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress

Koo, J. W., & Duman, R. S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708092105 · Cited by 862 · see citing works

Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment

Malberg, J. E., & Duman, R. S. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300234 · Cited by 815 · see citing works

Brain inflammation and adult neurogenesis: The dual role of microglia

Ekdahl, C. T., Kokaia, Z., & Lindvall, O. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.052 · Cited by 801 · see citing works

Stress and adult neurogenesis

Mirescu, C., & Gould, E. (2006) · Hippocampus · doi:10.1002/hipo.20155 · Cited by 701 · see citing works

Antidepressants increase neural progenitor cells in the human hippocampus

Boldrini, M., Underwood, M. D., Hen, R., Rosoklija, G. B., Dwork, A. J., John Mann, J., & Arango, V. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.75 · Cited by 686 · see citing works

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

Kreisel, T., Frank, M. G., Licht, T., Reshef, R., Ben-Menachem-Zidon, O., Baratta, M. V., Maier, S. F., & Yirmiya, R. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.155 · Cited by 663 · see citing works

Repeated restraint stress suppresses neurogenesis and induces biphasic PSA‐NCAM expression in the adult rat dentate gyrus

Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02513.x · Cited by 657 · see citing works

Early-life programming of later-life brain and behavior: a critical role for the immune system

Bilbo, S. D. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.014.2009 · Cited by 652 · see citing works

The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior

Schmidt, H. D., & Duman, R. S. (2007) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3282ee2aa8 · Cited by 649 · see citing works

Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum

Teicher, M. H., Anderson, C. M., & Polcari, A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115396109 · Cited by 639 · see citing works

Neural stem cell proliferation is decreased in schizophrenia, but not in depression

Reif, A., Fritzen, S., Finger, M., Strobel, A., Lauer, M., Schmitt, A., & Lesch, K.-P. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001791 · Cited by 630 · see citing works

Early life experience alters response of adult neurogenesis to stress

Mirescu, C., Peters, J. D., & Gould, E. (2004) · Nature Neuroscience · doi:10.1038/nn1290 · Cited by 625 · see citing works

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

Banasr, M., & Duman, R. S. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.008 · Cited by 606 · see citing works

Reduced Hippocampal Neurogenesis in Adult Transgenic Mice with Chronic Astrocytic Production of Interleukin-6

Vallières, L., Campbell, I. L., Gage, F. H., & Sawchenko, P. E. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-02-00486.2002 · Cited by 598 · see citing works

Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

Surget, A., Saxe, M., Leman, S., Ibarguen-Vargas, Y., Chalon, S., Griebel, G., Hen, R., & Belzung, C. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.02.022 · Cited by 556 · see citing works

Adult hippocampal neurogenesis is involved in anxiety-related behaviors

Revest, J.-M., Dupret, D., Koehl, M., Funk-Reiter, C., Grosjean, N., Piazza, P.-V., & Abrous, D. N. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.15 · Cited by 549 · see citing works

Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats

Aisa, B., Tordera, R. M., Lasheras, B., Rı́o, J. D., & Ramírez, M. J. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.12.013 · Cited by 534 · see citing works

Early experience and the development of stress reactivity and regulation in children

Loman, M. M., & Gunnar, M. R. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.05.007 · Cited by 489 · see citing works

Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain

Manganas, L. N., Zhang, X., Li, Y., Hazel, R. D., Smith, S. D. B., Wagshul, M. E., Henn, F. A., Benveniste, H., Djurić, P. M., Enikolopov, G., et al. (2007) · Science · doi:10.1126/science.1147851 · Cited by 486 · see citing works

Mechanisms of late-onset cognitive decline after early-life stress

Brunson, K. L., Kramár, E., Lin, B., Chen, Y., Colgin, L. L., Yanagihara, T. K., Lynch, G., & Baram, T. Z. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2281-05.2005 · Cited by 479 · see citing works

Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus

Kronenberg, G., Bick-Sander, A., Bunk, E., Wolf, C., Ehninger, D., & Kempermann, G. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.09.016 · Cited by 477 · see citing works

Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys

Coe, C. L., Kramer, M., Czéh, B., Gould, E., Reeves, A. J., Kirschbaum, C., & Fuchs, E. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00698-x · Cited by 477 · see citing works

Antidepressants recruit new neurons to improve stress response regulation

Surget, A., Tanti, A., Leonardo, E. D., Laugeray, A., Rainer, Q., Touma, C., Palme, R., Griebel, G., Ibarguen-Vargas, Y., Hen, R., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.48 · Cited by 471 · see citing works

Tumor Necrosis Factor Receptor 1 Is a Negative Regulator of Progenitor Proliferation in Adult Hippocampal Neurogenesis

Iosif, R. E., Ekdahl, C. T., Ahlenius, H., Pronk, C. J., Bonde, S., Kokaia, Z., Jacobsen, S. E. W., & Lindvall, O. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2723-06.2006 · Cited by 462 · see citing works

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action☆

Lucassen, P. J., Meerlo, P., Naylor, A. S., van Dam, A. M., Dayer, A. G., Fuchs, E., Oomen, C. A., & Czéh, B. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2009.08.003 · Cited by 449 · see citing works

Neuropathology of stress

Lucassen, P. J., Pruessner, J. C., Sousa, N., Almeida, O. F. X., Dam, A. M. V., Rajkowska, G., Swaab, D. F., & Czéh, B. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1223-5 · Cited by 449 · see citing works

Astroglial Plasticity in the Hippocampus is Affected by Chronic Psychosocial Stress and Concomitant Fluoxetine Treatment

Czéh, B., Simon, M., Schmelting, B., Hiemke, C., & Fuchs, E. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300982 · Cited by 434 · see citing works

Unraveling the Time Domains of Corticosteroid Hormone Influences on Brain Activity: Rapid, Slow, and Chronic Modes

Joëls, M., Sarabdjitsingh, R. A., & Karst, H. (2012) · Pharmacological Reviews · doi:10.1124/pr.112.005892 · Cited by 425 · see citing works

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

Hinwood, M., Morandini, J., Day, T. A., & Walker, F. R. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhr229 · Cited by 420 · see citing works

Distribution of corticosteroid receptors in the rhesus brain, relative absence of glucocorticoid receptors in the hippocampal formation

Sánchez, M. M., Young, L. J., Plotsky, P. M., & Insel, T. R. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-12-04657.2000 · Cited by 420 · see citing works

What causes the hippocampal volume decrease in depression?: Are neurogenesis, glial changes and apoptosis implicated?

Czéh, B., & Lucassen, P. J. (2007) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-007-0728-0 · Cited by 419 · see citing works

Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors

Ivy, A. S., Rex, C. S., Chen, Y., Dubé, C., Maras, P. M., Grigoriadis, D. E., Gall, C. M., Lynch, G., & Baram, T. Z. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1784-10.2010 · Cited by 402 · see citing works

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

Zunszain, P. A., Anacker, C., Cattaneo, A., Choudhury, S., Musaelyan, K., Myint, A. M., Thuret, S., Price, J., & Pariante, C. M. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.277 · Cited by 388 · see citing works

Adult hippocampal neurogenesis: Regulation, functional implications, and contribution to disease pathology

Balu, D. T., & Lucki, I. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.08.007 · Cited by 382 · see citing works

Mice with Genetically Altered Glucocorticoid Receptor Expression Show Altered Sensitivity for Stress-Induced Depressive Reactions

Ridder, S., Chourbaji, S., Hellweg, R., Urani, A., Zacher, C., Schmid, W., Zink, M., Hörtnagl, H., Flor, H., Henn, F. A., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.0736-05.2005 · Cited by 382 · see citing works

Chronic stress: Implications for neuronal morphology, function and neurogenesis

Joëls, M., Karst, H., Krugers, H. J., & Lucassen, P. J. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.04.001 · Cited by 381 · see citing works

Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis

Czéh, B., Welt, T., Fischer, A., Erhardt, A., Schmitt, W. B., Müller, M. B., Toschi, N., Fuchs, E., & Keck, M. E. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01457-9 · Cited by 370 · see citing works

All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis

Vivar, C., Potter, M. C., & van Praag, H. (2012) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2012_220 · Cited by 370 · see citing works

Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance.

Liston, C., Cichon, J. M., Jeanneteau, F., Jia, Z., Chao, M. V., & Gan, W.-B. (2013) · Nature Neuroscience · doi:10.1038/nn.3387 · Cited by 358 · see citing works

Severe Early Life Stress Hampers Spatial Learning and Neurogenesis, but Improves Hippocampal Synaptic Plasticity and Emotional Learning under High-Stress Conditions in Adulthood

Oomen, C. A., Soeters, H., Audureau, N., Vermunt, L., van Hasselt, F. N., Manders, E. M. M., Joëls, M., Lucassen, P. J., & Krugers, H. J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0247-10.2010 · Cited by 352 · see citing works

Hippocampal Angiogenesis and Progenitor Cell Proliferation Are Increased with Antidepressant Use in Major Depression

Boldrini, M., Hen, R., Underwood, M. D., Rosoklija, G. B., Dwork, A. J., Mann, J. J., & Arango, V. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.04.024 · Cited by 348 · see citing works

Why and how physical activity promotes experience-induced brain plasticity.

Kempermann, G., Fabel, K., Ehninger, D., Babu, H., Leal-Galicia, P., Garthe, A., & Wolf, S. A. (2010) · Frontiers in Neuroscience · doi:10.3389/fnins.2010.00189 · Cited by 334 · see citing works

Stress regulation in the central nervous system: evidence from structural and functional neuroimaging studies in human populations - 2008 Curt Richter Award Winner

Pruessner, J. C., Dedovic, K., Pruessner, M., Lord, C., Buss, C., Collins, L., Dagher, A., & Lupien, S. J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.02.016 · Cited by 333 · see citing works

Effects of long-term voluntary exercise on the mouse hypothalamic–pituitary–adrenocortical axis

Droste, S. K., Gesing, A., Ulbricht, S., Müller, M. B., Linthorst, A. C. E., & Reul, J. M. H. M. (2003) · Endocrinology · doi:10.1210/en.2003-0097 · Cited by 324 · see citing works

Antidepressant effects of exercise: Evidence for an adult-neurogenesis hypothesis?

Ernst, C., Olson, A. K., Pinel, J. P. J., Lam, R. W., & Christie, B. R. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0610 · Cited by 322 · see citing works

Blockade of CRF1 or V1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression

Alonso, R., Griebel, G., Pavone, G., Stemmelin, J., Fur, G. L., & Soubrié, P. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001464 · Cited by 319 · see citing works

Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible

Heine, V. M., Maslam, S., Zareno, J., Joëls, M., & Lucassen, P. J. (2004) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.03100.x · Cited by 317 · see citing works

Running throughout middle-age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL/6J mice

Marlatt, M. W., Potter, M. C., Lucassen, P. J., & van Praag, H. (2012) · Developmental Neurobiology · doi:10.1002/dneu.22009 · Cited by 314 · see citing works

Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis

Anacker, C., Cattaneo, A., Luoni, A., Musaelyan, K., Zunszain, P. A., Milanesi, E., Rybka, J., Berry, A., Cirulli, F., Thuret, S., et al. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.253 · Cited by 313 · see citing works

Neurogenic niche modulation by activated microglia: transforming growth factor β increases neurogenesis in the adult dentate gyrus

Battista, D., Ferrari, C. C., Gage, F. H., & Pitossi, F. J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04539.x · Cited by 306 · see citing works

Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury

Ziv, Y., Avidan, H., Pluchino, S., Martino, G., & Schwartz, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603747103 · Cited by 285 · see citing works

Isoflurane Anesthesia Induced Persistent, Progressive Memory Impairment, Caused a Loss of Neural Stem Cells, and Reduced Neurogenesis in Young, but Not Adult, Rodents

Zhu, C., Gao, J., Karlsson, N., Li, Q., Zhang, Y., Huang, Z., Li, H., Kuhn, H. G., & Blomgren, K. (2010) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2009.274 · Cited by 283 · see citing works

Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice

Naninck, E. F. G., Hoeijmakers, L., Kakava-Georgiadou, N., Meesters, A., Lazic, S. E., Lucassen, P. J., & Kőrösi, A. (2014) · Hippocampus · doi:10.1002/hipo.22374 · Cited by 281 · see citing works

Fragmentation and Unpredictability of Early-Life Experience in Mental Disorders

Baram, T. Z., Davis, E. P., Obenaus, A., Sandman, C. A., Small, S. L., Solodkin, A., & Stern, H. S. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11091347 · Cited by 268 · see citing works

Gonadal hormone modulation of neurogenesis in the dentate gyrus of adult male and female rodents

Galea, L. A. M. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.05.008 · Cited by 252 · see citing works

Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus

Chetty, S., Friedman, A., Taravosh-Lahn, K., Kirby, E. D., Mirescu, C., Guo, F., Krupik, D., Nicholas, A., Geraghty, A., Krishnamurthy, A., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.190 · Cited by 245 · see citing works

Necessity of hippocampal neurogenesis for the therapeutic action of antidepressants in adult nonhuman primates

Perera, T. D., Dwork, A. J., Keegan, K. A., Thirumangalakudi, L., Lipira, C. M., Joyce, N., Lange, C., Higley, J. D., Rosoklija, G., Hen, R., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017600 · Cited by 244 · see citing works

New neurons for 'survival of the fittest'

Kempermann, G. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3319 · Cited by 236 · see citing works

Microglia: A new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research

Morris, G. P., Clark, I. A., Zinn, R., & Vissel, B. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.07.002 · Cited by 236 · see citing works

Loss of brain volume in endogenous Cushing's syndrome and its reversibility after correction of hypercortisolism.

Bourdeau, I., Bard, C., Noël, B., Leclerc, I., Cordeau, M., Bélair, M., Lesage, J., Lafontaine, L., & Lacroix, A. (2002) · Journal of Clinical Endocrinology and Metabolism · doi:10.1210/jcem.87.5.8493 · Cited by 236 · see citing works

Adult hippocampal neurogenesis and voluntary running activity: Circadian and dose‐dependent effects

Holmes, M. M., Galea, L. A. M., Mistlberger, R. E., & Kempermann, G. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20039 · Cited by 233 · see citing works

Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour

Harris, A. P., Holmes, M. C., de Kloet, E. R., Chapman, K. E., & Seckl, J. R. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.08.007 · Cited by 231 · see citing works

Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress

Oomen, C. A., Mayer, J. L., de Kloet, E. R., Joëls, M., & Lucassen, P. J. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05972.x · Cited by 231 · see citing works

Reduced cell proliferation in the dentate gyrusis not correlated with the development of learned helplessness

Vollmayr, B., Simonis, C., Weber, S., Gass, P., & Henn, F. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00527-4 · Cited by 229 · see citing works

Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory

Parihar, V. K., Hattiangady, B., Kuruba, R., Shuai, B., & Shetty, A. K. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.130 · Cited by 225 · see citing works

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression

Heine, V. M., Zareno, J., Maslam, S., Joëls, M., & Lucassen, P. J. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03951.x · Cited by 225 · see citing works

The contribution of failing adult hippocampal neurogenesis to psychiatric disorders

Kempermann, G., Krebs, J., & Fabel, K. S. (2008) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3282fad375 · Cited by 223 · see citing works

Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients

Lucassen, P. J., Stumpel, M. W., Wang, Q., & Aronica, E. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.01.012 · Cited by 213 · see citing works

Early Stress Evokes Age-Dependent Biphasic Changes in Hippocampal Neurogenesis, Bdnf Expression, and Cognition

Suri, D., Veenit, V., Sarkar, A., Thiagarajan, D., Kumar, A., Nestler, E. J., Galande, S., & Vaidya, V. A. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.10.023 · Cited by 208 · see citing works

Maternal care influences neuronal survival in the hippocampus of the rat

Bredy, T. W., Grant, R. J., Champagne, D. L., & Meaney, M. J. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.02965.x · Cited by 208 · see citing works

Hippocampal neurogenesis and gene expression depend on exercise intensity in juvenile rats

Lou, S., Liu, J., Chang, H., & Chen, P. (2008) · Brain Research · doi:10.1016/j.brainres.2008.02.080 · Cited by 206 · see citing works

Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain

Naylor, A. S., Bull, C., Nilsson, M. K. L., Zhu, C., Björk‐Eriksson, T., Eriksson, P. S., Blomgren, K., & Kuhn, H. G. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711128105 · Cited by 205 · see citing works

Early-life stress mediated modulation of adult neurogenesis and behavior

Korosi, A., Naninck, E. F. G., Oomen, C. A., Schouten, M., Krugers, H., Fitzsimons, C., & Lucassen, P. J. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.07.037 · Cited by 194 · see citing works

The Brain as a Target for Inflammatory Processes and Neuroprotective Strategies

Skaper, S. D. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1403.002 · Cited by 191 · see citing works

Opposite effects of early maternal deprivation on neurogenesis in male versus female rats

Oomen, C. A., Girardi, C. E. N., Cahyadi, R., Verbeek, E. C., Krugers, H., Joëls, M., & Lucassen, P. J. (2009) · PLoS ONE · doi:10.1371/journal.pone.0003675 · Cited by 190 · see citing works

The role of N ‐methyl‐ D ‐asparate receptors in neurogenesis

Nácher, J., & McEwen, B. S. (2006) · Hippocampus · doi:10.1002/hipo.20160 · Cited by 189 · see citing works

Stressor-specific regulation of distinct brain-derived neurotrophic factor transcripts and cyclic AMP response element-binding protein expression in the postnatal and adult rat hippocampus

Nair, A., Vadodaria, K. C., Banerjee, S. B., Benekareddy, M., Dias, B. G., Duman, R. S., & Vaidya, V. A. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301276 · Cited by 189 · see citing works

Brief Treatment With the Glucocorticoid Receptor Antagonist Mifepristone Normalises the Corticosterone‐Induced Reduction of Adult Hippocampal Neurogenesis

Mayer, J. L., Klumpers, L. E., Maslam, S., de Kloet, E. R., Joëls, M., & Lucassen, P. J. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01455.x · Cited by 181 · see citing works

Glial cells in adult neurogenesis

Morrens, J., Broeck, W. V. D., & Kempermann, G. (2011) · Glia · doi:10.1002/glia.21247 · Cited by 180 · see citing works

Structural changes in hippocampal subfields in major depressive disorder: a high-field magnetic resonance imaging study

Huang, Y., Coupland, N. J., Lebel, R. M., Carter, R., Seres, P., Wilman, A. H., & Malykhin, N. V. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.005 · Cited by 179 · see citing works

The corticoid environment: a determining factor for neural progenitors' survival in the adult hippocampus

Wong, E. Y. H., & Herbert, J. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03717.x · Cited by 179 · see citing works

Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production

Ravizza, T., Noè, F. M., Zardoni, D., Vaghi, V., Sifringer, M., & Vezzani, A. (2008) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.05.007 · Cited by 178 · see citing works

Transforming Growth Factor-β1 Is a Negative Modulator of Adult Neurogenesis

Wachs, F., Winner, B., Couillard‐Després, S., Schiller, T., Aigner, R., Winkler, J., Bogdahn, U., & Aigner, L. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000218444.53405.f0 · Cited by 174 · see citing works

Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics

Lucassen, P. J., Naninck, E. F. G., van Goudoever, J. B., Fitzsimons, C. P., Joëls, M., & Kőrösi, A. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.08.002 · Cited by 173 · see citing works

Running is rewarding and antidepressive

Brené, S., Bjørnebekk, A., Åberg, E., Mathé, A. A., Olson, L., & Werme, M. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.05.015 · Cited by 172 · see citing works

STRESS EXPOSURE ACROSS THE LIFE SPAN CUMULATIVELY INCREASES DEPRESSION RISK AND IS MODERATED BY NEUROTICISM

Vinkers, C. H., Joëls, M., Milaneschi, Y., Kahn, R. S., Penninx, B. W. J. H., & Boks, M. P. (2014) · Depression and Anxiety · doi:10.1002/da.22262 · Cited by 170 · see citing works

Glucocorticoids Orchestrate Divergent Effects on Mood through Adult Neurogenesis

Lehmann, M. L., Brachman, R. A., Martinowich, K., Schloesser, R. J., & Herkenham, M. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3878-12.2013 · Cited by 168 · see citing works

Corticosteroid receptors and neuroplasticity

Sousa, N., Cerqueira, J., & Almeida, O. F. X. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.06.007 · Cited by 166 · see citing works

Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb

Kaneko, N., Okano, H., & Sawamoto, K. (2006) · Genes to Cells · doi:10.1111/j.1365-2443.2006.01010.x · Cited by 162 · see citing works

Parenting and plasticity

Leuner, B., Glasper, E. R., & Gould, E. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.07.003 · Cited by 159 · see citing works

Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus

Wong, E. Y. H., & Herbert, J. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04277.x · Cited by 155 · see citing works

Effect of Inflammatory Cytokines on Major Histocompatibility Complex Expression and Differentiation of Human Neural Stem/Progenitor Cells

Johansson, S., Price, J., & Modo, M. (2008) · Stem Cells · doi:10.1634/stemcells.2008-0116 · Cited by 148 · see citing works

Inflammation Regulates Functional Integration of Neurons Born in Adult Brain

Jakubs, K., Bonde, S., Iosif, R. E., Ekdahl, C. T., Kokaia, Z., Kokaia, M., & Lindvall, O. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3240-08.2008 · Cited by 148 · see citing works

Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior

Fitzsimons, C. P., van Hooijdonk, L. W. A., Schouten, M., Zalachoras, I., Brinks, V., Zheng, T., Schouten, T. G., Saaltink, D., Dijkmans, T. F., Steindler, D. A., et al. (2012) · Molecular Psychiatry · doi:10.1038/mp.2012.123 · Cited by 147 · see citing works

Glucocorticoid receptor protein expression in human hippocampus; stability with age

Wang, Q., Van Heerikhuize, J., Aronica, E., Kawata, M., Seress, L., Joels, M., Swaab, D. F., & Lucassen, P. J. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.11.019 · Cited by 144 · see citing works

Prenatal stress reduces postnatal neurogenesis in rats selectively bred for high, but not low, anxiety: possible key role of placental 11β‐hydroxysteroid dehydrogenase type 2

Lucassen, P. J., Bosch, O. J., Jousma, E., Krömer, S. A., Andrew, R., Seckl, J. R., & Neumann, I. D. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06543.x · Cited by 140 · see citing works

Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems

Joca, S. R. L., Ferreira, F. R., & Guimarães, F. S. (2007) · Stress · doi:10.1080/10253890701223130 · Cited by 137 · see citing works

Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain

Bland, S. T., Beckley, J. T., Young, S., Tsang, V., Watkins, L. R., Maier, S. F., & Bilbo, S. D. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2009.09.012 · Cited by 136 · see citing works

Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats

Oomen, C. A., Soeters, H., Audureau, N., Vermunt, L., van Hasselt, F. N., Manders, E. M. M., Joëls, M., Krugers, H. J., & Lucassen, P. J. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1922-8 · Cited by 133 · see citing works

Age‐dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells

Fukuda, A., Fukuda, H., Swanpalmer, J., Hertzman, S., Lannering, B., Márky, I., Björk‐Eriksson, T., & Blomgren, K. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02894.x · Cited by 130 · see citing works

Predator Exposure/Psychosocial Stress Animal Model of Post-Traumatic Stress Disorder Modulates Neurotransmitters in the Rat Hippocampus and Prefrontal Cortex

Wilson, C. B., Ebenezer, P. J., McLaughlin, L. D., & Francis, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089104 · Cited by 129 · see citing works

Reduction in hippocampal neurogenesis after social defeat is long-lasting and responsive to late antidepressant treatment

van Bokhoven, P., Oomen, C. A., Hoogendijk, W. J. G., Smit, A. B., Lucassen, P. J., & Spijker, S. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07668.x · Cited by 128 · see citing works

Extended voluntary running inhibits exercise-induced adult hippocampal progenitor proliferation in the spontaneously hypertensive rat.

Naylor, A. S., Persson, A. I., Eriksson, P. S., Jonsdottir, I. H., & Thorlin, T. (2005) · Journal of Neurophysiology · doi:10.1152/jn.01085.2004 · Cited by 127 · see citing works

Increased adult hippocampal brain‐derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats

Greisen, M. H., Altar, C. A., Bolwig, T. G., Whitehead, R. E., & Wörtwein, G. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20418 · Cited by 120 · see citing works

Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder

Medina, A., Seasholtz, A. F., Sharma, V., Burke, S., Bunney, W. E., Myers, R., Schatzberg, A. F., Akil, H., & Watson, S. J. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.11.002 · Cited by 120 · see citing works

Age- and Sex-Dependent Effects of Early Life Stress on Hippocampal Neurogenesis

Loi, M., Koricka, S., Lucassen, P. J., & Joëls, M. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00013 · Cited by 120 · see citing works

Adult neurogenesis: bridging the gap between mice and humans

Jessberger, S., & Gage, F. H. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.07.003 · Cited by 116 · see citing works

Cholinergic influences on cortical development and adult neurogenesis

Bruel‐Jungerman, E., Lucassen, P. J., & Francis, F. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.01.021 · Cited by 110 · see citing works

Circadian and ultradian rhythms of free glucocorticoid hormone are highly synchronized between the blood, the subcutaneous tissue, and the brain

Qian, X., Droste, S. K., Lightman, S. L., Reul, J. M. H. M., & Linthorst, A. C. E. (2012) · Endocrinology · doi:10.1210/en.2012-1484 · Cited by 110 · see citing works

Paradoxical effects of learning the Morris water maze on adult hippocampal neurogenesis in mice may be explained by a combination of stress and physical activity

Ehninger, D., & Kempermann, G. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2005.00129.x · Cited by 108 · see citing works

Serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals

Djavadian, R. L. (2004) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2004-1505 · Cited by 108 · see citing works

Distribution of the glucocorticoid receptor in the human amygdala; changes in mood disorder patients

Wang, Q., Verweij, E. W. E., Krugers, H. J., Joëls, M., Swaab, D. F., & Lucassen, P. J. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0589-4 · Cited by 107 · see citing works

Running reduces stress and enhances cell genesis in aged mice

Kannangara, T. S., Lucero, M. J., Gil-Mohapel, J., Drapala, R. J., Simpson, J. M., Christie, B. R., & van Praag, H. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.12.025 · Cited by 107 · see citing works

A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats

Bilbo, S. D., Rudy, J. W., Watkins, L. R., & Maier, S. F. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.12.002 · Cited by 106 · see citing works

Maintenance of Hippocampal Cell Numbers in Young and Aged Rats Submitted to Chronic Unpredictable Stress. Comparison with the Effects of Corticosterone Treatment

Sousa, N., Almeida, O. F. X., Holsboer, F., Paula-Barbosa, M. M., & Madeira, M. D. (1998) · Stress · doi:10.3109/10253899809167288 · Cited by 105 · see citing works

Chronic cocaine exposure impairs progenitor proliferation but spares survival and maturation of neural precursors in adult rat dentate gyrus

Domínguez‐Escribá, L., Hernández‐Rabaza, V., Soriano‐Navarro, M., Barcia, J. A., Romero, F. J., García‐Verdugo, J. M., & Canales, J. J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04924.x · Cited by 100 · see citing works

The transcriptional response to chronic stress and glucocorticoid receptor blockade in the hippocampal dentate gyrus

Datson, N. A., Speksnijder, N., Mayer, J. L., Steenbergen, P. J., Korobko, O. B., Goeman, J. J., de Kloet, E. R., Joëls, M., & Lucassen, P. J. (2010) · Hippocampus · doi:10.1002/hipo.20905 · Cited by 100 · see citing works

Aberrant stress hormone receptor balance in the human prefrontal cortex and hypothalamic paraventricular nucleus of depressed patients

Qi, X., Kamphuis, W., Wang, S., Wang, Q., Lucassen, P. J., Zhou, J., & Swaab, D. F. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.09.014 · Cited by 97 · see citing works

Adult hippocampal neurogenesis and its role in cognition.

Oomen, C. A., Bekinschtein, P., Kent, B. A., Saksida, L. M., & Bussey, T. J. (2014) · WIREs Cognitive Science · doi:10.1002/wcs.1304 · Cited by 93 · see citing works

Differential Effects of Stress and Glucocorticoids on Adult Neurogenesis

Schoenfeld, T. J., & Gould, E. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2012_233 · Cited by 89 · see citing works

Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood

Bilbo, S. D., Newsum, N. J., Sprunger, D. B., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.10.005 · Cited by 88 · see citing works

Mother's affection at 8 months predicts emotional distress in adulthood

Maselko, J., Kubzansky, L. D., Lipsitt, L. P., & Buka, S. L. (2010) · Journal of Epidemiology & Community Health · doi:10.1136/jech.2009.097873 · Cited by 88 · see citing works

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

Miller, J. A., Nathanson, J. L., Franjic, D., Shim, S., Dalley, R. A., Shapouri, S., Smith, K. A., Sunkin, S. M., Bernard, A., Bennett, J. L., et al. (2013) · Development · doi:10.1242/dev.097212 · Cited by 86 · see citing works

The effect of dopamine on adult hippocampal neurogenesis

Takamura, N., Nakagawa, S., Masuda, T., Boku, S., Kato, A., Song, N., An, Y., Kitaichi, Y., Inoue, T., Koyama, T., et al. (2014) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.12.011 · Cited by 86 · see citing works

Implication of corticosteroid receptors in the regulation of hippocampal structural plasticity

Montaron, M., Piazza, P. V., Aurousseau, C., Urani, A., Moal, M. L., & Abrous, D. N. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.03048.x · Cited by 82 · see citing works

Impact of Social Status and Antidepressant Treatment on Neurogenesis in the Baboon Hippocampus

Wu, M. V., Shamy, J. L., Bedi, G., Choi, C.-W. J., Wall, M. M., Arango, V., Boldrini, M., Foltin, R. W., & Hen, R. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.33 · Cited by 77 · see citing works

Maternal behavior regulates long‐term hippocampal expression of BAX and apoptosis in the offspring

Weaver, I. C. G., Grant, R. J., & Meaney, M. J. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01054.x · Cited by 73 · see citing works

Overexpressing the Glucocorticoid Receptor in Forebrain Causes an Aging-Like Neuroendocrine Phenotype and Mild Cognitive Dysfunction

Wei, Q., Hebda‐Bauer, E. K., Pletsch, A., Luo, J., Hoversten, M. T., Osetek, A. J., Evans, S. J., Watson, S. J., Seasholtz, A. F., & Akil, H. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0910-07.2007 · Cited by 71 · see citing works

Radiation Therapy for Pediatric Central Nervous System Tumors

Hoffman, K. E., & Yock, T. I. (2009) · Journal of Child Neurology · doi:10.1177/0883073809342275 · Cited by 68 · see citing works

Corticotropin-releasing hormone expression is the major target for glucocorticoid feedback-control at the hypothalamic level

Kretz, O., Reichardt, H. M., Schütz, G., & Bock, R. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01277-3 · Cited by 66 · see citing works

New Neurons in Aging Brains: Molecular Control by Small Non-Coding RNAs

Schouten, M., Buijink, M. R., Lucassen, P. J., & Fitzsimons, C. P. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00025 · Cited by 64 · see citing works

A Single-Day Treatment with Mifepristone Is Sufficient to Normalize Chronic Glucocorticoid Induced Suppression of Hippocampal Cell Proliferation

Hu, P., Oomen, C. A., van Dam, A., Wester, J., Zhou, J., Joëls, M., & Lucassen, P. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046224 · Cited by 58 · see citing works

Prenatal Stress Inhibits Hippocampal Neurogenesis but Spares Olfactory Bulb Neurogenesis

Belnoue, L., Grosjean, N., Ladevèze, E., Abrous, D. N., & Koehl, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072972 · Cited by 58 · see citing works

Neonatal Maternal Separation Alters the Capacity of Adult Neural Precursor Cells to Differentiate into Neurons Via Methylation of Retinoic Acid Receptor Gene Promoter

Boku, S., Toda, H., Nakagawa, S., Kato, A., Inoue, T., Koyama, T., Hiroi, N., & Kusumi, I. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.07.008 · Cited by 56 · see citing works

Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL‐1ra in the mouse

Spulber, S. D., Oprica, M., Bartfai, T., Winblad, B. G., & Schultzberg, M. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06050.x · Cited by 54 · see citing works

Increased P27KIP1 protein expression in the dentate gyrus of chronically stressed rats indicates G1 arrest involvement

Heine, V. M., Maslam, S., Joëls, M., & Lucassen, P. J. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.07.048 · Cited by 54 · see citing works

In vitro Neurogenesis from Neural Progenitor Cells Isolated from the Hippocampus Region of the Brain of Adult Rats Exposed to Ethanol during Early Development through Their Alcohol-Drinking Mothers

Singh, A. K., Gupta, S., Jiang, Y., Younus, M., & Ramzan, M. (2009) · Alcohol and Alcoholism · doi:10.1093/alcalc/agn109 · Cited by 50 · see citing works

Modulation of Adult Hippocampal Neurogenesis by Early-Life Environmental Challenges Triggering Immune Activation

Musaelyan, K., Egeland, M. T., Fernandes, C., Pariante, C. M., Zunszain, P. A., & Thuret, S. (2014) · Neural Plasticity · doi:10.1155/2014/194396 · Cited by 47 · see citing works

Can adult neurogenesis buffer stress responses and depressive behaviour?

Anacker, C., & Pariante, C. M. (2012) · Molecular Psychiatry · doi:10.1038/mp.2011.133 · Cited by 45 · see citing works

Hippocampal GR expression is increased in elderly depressed females

Wang, Q., Joëls, M., Swaab, D. F., & Lucassen, P. J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.09.014 · Cited by 43 · see citing works

Sexual activity counteracts the suppressive effects of chronic stress on adult hippocampal neurogenesis and recognition memory

Kim, J., Lee, J., Lee, Y. A., Lee, D. H., Han, N. S., Choi, Y.-K., Hwang, B. R., Kim, H. J., & Han, J. S. (2013) · Brain Research · doi:10.1016/j.brainres.2013.09.007 · Cited by 42 · see citing works

Genetic Dissection of Glucocorticoid Receptor Function in the Mouse Brain

Erdmann, G., Berger, S., & Schütz, G. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01717.x · Cited by 34 · see citing works

Altered Fate of Subventricular Zone Progenitor Cells and Reduced Neurogenesis following Neonatal Stroke

Spadafora, R., Gonzalez, F. F., Derugin, N., Wendland, M. F., Ferriero, D. M., & McQuillen, P. S. (2010) · Developmental Neuroscience · doi:10.1159/000279654 · Cited by 33 · see citing works

Examining SLV-323, a novel NK1 receptor antagonist, in a chronic psychosocial stress model for depression

Czéh, B., Pudovkina, O., van der Hart, M. G. C., Simon, M., Heilbronner, U., Michaelis, T., Watanabe, T., Frahm, J., & Fuchs, E. (2005) · Psychopharmacology · doi:10.1007/s00213-005-2184-8 · Cited by 33 · see citing works

Stressing new neurons into depression?

Lucassen, P. J., Fitzsimons, C. P., Kőrösi, A., Joëls, M., Belzung, C., & Abrous, D. N. (2012) · Molecular Psychiatry · doi:10.1038/mp.2012.39 · Cited by 29 · see citing works

Blockade of CRF1 or V1B receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression

Alonso, R., Griebel, G., Pavone, G., Stemmelin, J., Fur, G. L., & Soubrié, P. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001484 · Cited by 28 · see citing works

Interplay of Maternal Care and Genetic Influences in Programming Adult Hippocampal Neurogenesis

Koehl, M., van der Veen, R., Gonzales, D., Piazza, P. V., & Abrous, D. N. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.03.001 · Cited by 22 · see citing works

No Long‐Term Effect Two Years after Intrauterine Exposure to Dexamethasone on Dentate Gyrus Volume, Neuronal Proliferation and Differentiation in Common Marmoset Monkeys

Tauber, S. C., Bunkowski, S., Schlumbohm, C., Rühlmann, M., Fuchs, E., Nau, R., & Gerber, J. (2008) · Brain Pathology · doi:10.1111/j.1750-3639.2008.00149.x · Cited by 18 · see citing works

Depression and interferon-alpha therapy

Cassidy, E., & O’Keane, V. (2000) · The British Journal of Psychiatry · doi:10.1192/bjp.176.5.494-a · Cited by 17 · see citing works

Age‐dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells

Fukuda, A., Fukuda, H., Swanpalmer, J., Hertzman, S., Lannering, B., Márky, I., Björk‐Eriksson, T., & Blomgren, K. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03504.x · Cited by 6 · see citing works

Neurogenesis in the adult hippocampus

Kempermann, G., Song, H., & Gage, F. H. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018812 · Cited by 1,072 · see citing works

Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood

Anacker, C., & Hen, R. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.45 · Cited by 1,014 · see citing works

Human Adult Neurogenesis: Evidence and Remaining Questions

Kempermann, G., Gage, F. H., Aigner, L., Song, H., Curtis, M. A., Thuret, S., Kuhn, H. G., Jessberger, S., Frankland, P. W., Cameron, H. A., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.04.004 · Cited by 790 · see citing works

Quiescence of Adult Mammalian Neural Stem Cells: A Highly Regulated Rest

Urbán, N., Blomfield, I. M., & Guillemot, F. (2019) · Neuron · doi:10.1016/j.neuron.2019.09.026 · Cited by 370 · see citing works

Chronic stress and glucocorticoids: From neuronal plasticity to neurodegeneration

Vyas, S., Rodrigues, A. J., Silva, J. M., Tronche, F., Almeida, O. F. X., Sousa, N., & Sotiropoulos, I. (2016) · Neural Plasticity · doi:10.1155/2016/6391686 · Cited by 297 · see citing works

Microglia and the brain: Complementary partners in development and disease

Hammond, T. R., Robinton, D., & Stevens, B. (2018) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100616-060509 · Cited by 288 · see citing works

Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained

Nokia, M. S., Lensu, S., Ahtiainen, J. P., Johansson, P. P., Koch, L. G., Britton, S. L., & Kainulainen, H. (2016) · The Journal of Physiology · doi:10.1113/jp271552 · Cited by 257 · see citing works

Adult neurogenesis in mammals

Gage, F. H. (2019) · Science · doi:10.1126/science.aav6885 · Cited by 216 · see citing works

Maturation and Functional Integration of New Granule Cells into the Adult HippocampusPreprint

Toni, N., & Schinder, A. F. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018903 · Cited by 191 · see citing works

Adult Hippocampal Neurogenesis: Regulation and Possible Functional and Clinical Correlates

Baptista, P., & Andrade, J. P. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00044 · Cited by 162 · see citing works

Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder

Mahajan, G., Vallender, E. J., Garrett, M. R., Challagundla, L., Overholser, J. C., Jurjus, G., Dieter, L., Syed, M., Romero, D. G., Benghuzzi, H., et al. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.11.017 · Cited by 159 · see citing works

Functional Neurochemistry of the Ventral and Dorsal Hippocampus: Stress, Depression, Dementia and Remote Hippocampal Damage

Gulyaeva, N. V. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2662-0 · Cited by 156 · see citing works

Depression as a risk factor for Alzheimer’s disease: Genes, steroids, cytokines and neurogenesis – What do we need to know?

Herbert, J., & Lucassen, P. J. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2015.12.001 · Cited by 150 · see citing works

Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment

Kandola, A., Hendrikse, J., Lucassen, P. J., & Yücel, M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00373 · Cited by 155 · see citing works

Born this way: Hippocampal neurogenesis across the lifespan

Kozareva, D. A., Cryan, J. F., & Nolan, Y. M. (2019) · Aging Cell · doi:10.1111/acel.13007 · Cited by 146 · see citing works

Noise induced hearing loss impairs spatial learning/memory and hippocampal neurogenesis in mice

Liu, L., Shen, P., He, T., Chang, Y., Shi, L., Tao, S., Li, X., Xun, Q., Guo, X., Yu, Z., et al. (2016) · Scientific Reports · doi:10.1038/srep20374 · Cited by 131 · see citing works

The long and short term effects of motherhood on the brain

Duarte‐Guterman, P., Leuner, B., & Galea, L. A. M. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.02.004 · Cited by 127 · see citing works

Role and possible mechanisms of Sirt1 in depression

Lu, G., Li, J., Zhang, H., Zhao, X., Yan, L.-J., & Yang, X. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/8596903 · Cited by 106 · see citing works

Inflammation and Insulin Resistance as Risk Factors and Potential Therapeutic Targets for Alzheimer’s Disease

Vinuesa, Á., Pomilio, C. J., Gregosa, A., Bentivegna, M., Presa, J., Bellotto, M., Saravia, F., & Beauquis, J. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.653651 · Cited by 111 · see citing works

Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer’s disease

Ryan, S. M., & Kelly, A. M. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.03.007 · Cited by 104 · see citing works

Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis

Liu, L., Zhang, Q., Cai, Y., Sun, D., Xie, H., Wang, L., Yu, D., Li, X., Xiong, X., Xu, H., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.11178 · Cited by 103 · see citing works

Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression

Egeland, M., Guinaudie, C., Du Preez, A., Musaelyan, K., Zunszain, P. A., Fernandes, C., Pariante, C. M., & Thuret, S. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.68 · Cited by 98 · see citing works

Adult neurogenesis, human after all (again): Classic, optimized, and future approaches

Lucassen, P. J., Fitzsimons, C. P., Salta, E., & Maletić‐Savatić, M. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112458 · Cited by 93 · see citing works

REM sleep’s unique associations with corticosterone regulation, apoptotic pathways, and behavior in chronic stress in mice

Nollet, M., Hicks, H., McCarthy, A. P., Wu, H., Möller‐Levet, C. S., Laing, E., Malki, K., Lawless, N., Wafford, K. A., Dijk, D., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1816456116 · Cited by 94 · see citing works

Mesenchymal stem cells as a multimodal treatment for nervous system diseases

Badyra, B., Sułkowski, M., Milczarek, O., & Majka, M. (2020) · Stem Cells Translational Medicine · doi:10.1002/sctm.19-0430 · Cited by 86 · see citing works

FG-4592 Improves Depressive-Like Behaviors through HIF-1-Mediated Neurogenesis and Synapse Plasticity in Rats

Li, G., Zhao, M., Cheng, X., Zhao, T., Feng, Z., Zhao, Y., Fan, M., & Zhu, L. (2019) · Neurotherapeutics · doi:10.1007/s13311-019-00807-3 · Cited by 82 · see citing works

Biochemical Mechanisms and Translational Relevance of Hippocampal Vulnerability to Distant Focal Brain Injury: The Price of Stress Response

Gulyaeva, N. V. (2019) · Biochemistry (Moscow) · doi:10.1134/s0006297919110087 · Cited by 81 · see citing works

Human milk: From complex tailored nutrition to bioactive impact on child cognition and behavior

de Weerth, C., Aatsinki, A., Azad, M. B., Bartol, F. F., Bode, L., Collado, M. C., Dettmer, A. M., Field, C. J., Guilfoyle, M. M., Hinde, K., et al. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2053058 · Cited by 71 · see citing works

Adult hippocampal neurogenesis for systems consolidation of memory

Terranova, J. I., Ogawa, S. K., & 北村, 貴. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112035 · Cited by 69 · see citing works

High-intensity Intermittent Training Enhances Spatial Memory and Hippocampal Neurogenesis Associated with BDNF Signaling in Rats

Okamoto, M., Mizuuchi, D., Koki, O., Lee, M. C., Akihiko, O., Yook, J. S., Inoue, K., & Soya, H. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab093 · Cited by 65 · see citing works

Glucocorticoids Orchestrate Adult Hippocampal Plasticity: Growth Points and Translational Aspects

Gulyaeva, N. V. (2023) · Biochemistry (Moscow) · doi:10.1134/s0006297923050012 · Cited by 66 · see citing works

Disrupted Neurogenesis in Germ-Free Mice: Effects of Age and Sex

Scott, G. A., Terstege, D. J., Vu, A. P., Law, S., Evans, A., & Epp, J. R. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00407 · Cited by 64 · see citing works

Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder

Gandy, K. C., Kim, S., Sharp, C., Dindo, L. N., Maletić‐Savatić, M., & Calarge, C. A. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00571 · Cited by 62 · see citing works

Glucocorticoid‐mediated mechanisms of hippocampal damage: Contribution of subgranular neurogenesis

Podgorny, O. V., & Gulyaeva, N. V. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15265 · Cited by 59 · see citing works

Limits to human neurogenesis—really?

Lucassen, P. J., Toni, N., Kempermann, G., Frisén, J., Gage, F. H., & Swaab, D. F. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0337-5 · Cited by 59 · see citing works

The Effects of Early Life Stress on the Brain and Behaviour: Insights From Zebrafish Models

Eachus, H., Choi, M., & Ryu, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.657591 · Cited by 52 · see citing works

Spinal Cord Injury Impairs Neurogenesis and Induces Glial Reactivity in the Hippocampus

Jure, I., Pietranera, L., Nicola, A. F. D., & Labombarda, F. (2017) · Neurochemical Research · doi:10.1007/s11064-017-2225-9 · Cited by 55 · see citing works

Early-life stress alters affective behaviors in adult mice through persistent activation of CRH-BDNF signaling in the oval bed nucleus of the stria terminalis

Hu, P., Maita, I., Phan, M. L., Gu, E., Kwok, C., Dieterich, A., Gergues, M. M., Yohn, C. N., Wang, Y., Zhou, J.-N., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-01070-3 · Cited by 49 · see citing works

Brain Under Stress and Alzheimer’s Disease

Mravec, B., Horváthová, Ľ., & Padová, A. (2017) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-017-0521-1 · Cited by 53 · see citing works

High‐intensity treadmill running impairs cognitive behavior and hippocampal synaptic plasticity of rats via activation of inflammatory response

Sun, L., Li, X., Wang, F., Zhang, J., Wang, D., Yuan, L., Wu, M., Wang, Z.-J., & Qi, J. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23996 · Cited by 52 · see citing works

Combined corticosterone treatment and chronic restraint stress lead to depression associated with early cognitive deficits in mice

Ngoupaye, G. T., Yassi, F. B., Bahane, D. A. N., & Bum, E. N. (2017) · Metabolic Brain Disease · doi:10.1007/s11011-017-0148-4 · Cited by 47 · see citing works

Postnatal Lipopolysaccharide Exposure Impairs Adult Neurogenesis and Causes Depression-like Behaviors Through Astrocytes Activation Triggering GABAA Receptor Downregulation

Liang, M., Zhong, H., Rong, J., Li, Y., Zhu, C., Zhou, L., & Zhou, R. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.10.025 · Cited by 47 · see citing works

Retinoic acid and depressive disorders: Evidence and possible neurobiological mechanisms

Hu, P., van Dam, A., Wang, Y., Lucassen, P. J., & Zhou, J.-N. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.02.013 · Cited by 47 · see citing works

How the Body Talks to the Brain; Peripheral Mediators of Physical Activity-Induced Proliferation in the Adult Hippocampus

Bolijn, S., & Lucassen, P. J. (2015) · Brain Plasticity · doi:10.3233/bpl-150020 · Cited by 45 · see citing works

Hippocampal Mechanisms Underlying Impairment in Spatial Learning Long After Establishment of Noise-Induced Hearing Loss in CBA Mice

Liu, L., Xuan, C., Shen, P., He, T., Chang, Y., Shi, L., Tao, S., Yu, Z., Brown, R. E., & Wang, J. (2018) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2018.00035 · Cited by 45 · see citing works

Maternal pineal melatonin in gestation and lactation physiology, and in fetal development and programming

Gomes, P. R. L., Motta‐Teixeira, L. C., Gallo, C. C., Buonfiglio, D. D. C., de Camargo, L. S., Quintela, T., Reiter, R. J., do Amaral, F. G., & Cipolla‐Neto, J. (2020) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2020.113633 · Cited by 45 · see citing works

A Baldwin interpretation of adult hippocampal neurogenesis: from functional relevance to physiopathology

Abrous, D. N., Koehl, M., & Lemoine, M. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01172-4 · Cited by 45 · see citing works

Effects of gintonin-enriched fraction on hippocampal cell proliferation in wild-type mice and an APPswe/PSEN-1 double Tg mouse model of Alzheimer's disease

Kim, H., Kim, D.-J., Shin, E.-J., Lee, B.-H., Choi, S.-H., Hwang, S., Rhim, H., Cho, I., Kim, H., & Nah, S.-Y. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.10.006 · Cited by 43 · see citing works

Insult-induced aberrant hippocampal neurogenesis: Functional consequences and possible therapeutic strategies

Bielefeld, P., Durá, I., Danielewicz, J., Lucassen, P. J., Baekelandt, V., Abrous, D. N., Encinas, J. M., & Fitzsimons, C. P. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112032 · Cited by 41 · see citing works

Autistic-like behaviours and associated brain structural plasticity are modulated by oxytocin in maternally separated rats

Mansouri, M., Pouretemad, H., Roghani, M., Wegener, G., & Ardalan, M. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112756 · Cited by 43 · see citing works

Early Life Stress and Metabolic Plasticity of Brain Cells: Impact on Neurogenesis and Angiogenesis

Salmina, A. B., Gorina, Y. V., Komleva, Y. K., Panina, Y. A., Malinovskaya, N. A., & Lopatina, O. L. (2021) · Biomedicines · doi:10.3390/biomedicines9091092 · Cited by 41 · see citing works

Treatment with the glutamate modulator riluzole prevents early life stress-induced cognitive deficits and impairments in synaptic plasticity in APPswe/PS1dE9 mice

Lesuis, S. L., Kaplick, P. M., Lucassen, P. J., & Krugers, H. J. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.02.023 · Cited by 40 · see citing works

How Early Life Adversity Influences Defensive Circuitry

Murthy, S. S., & Gould, E. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.02.001 · Cited by 42 · see citing works

Transgenic mouse models for studying adult neurogenesis

Semerci, F., & Maletić‐Savatić, M. (2016) · Frontiers in Biology · doi:10.1007/s11515-016-1405-3 · Cited by 42 · see citing works

Genetic predisposition for high stress reactivity amplifies effects of early-life adversity

McIlwrick, S., Rechenberg, A., Matthes, M., Burgstaller, J., Schwarzbauer, T., Chen, A., & Touma, C. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.04.023 · Cited by 40 · see citing works

A Comprehensive Overview of Stress, Resilience, and Neuroplasticity Mechanisms

Buenrostro-Jáuregui, M. H., Muñoz-Sánchez, S., Rojas-Hernández, J., Alonso-Orozco, A. I., Vega‐Flores, G., Tapia-de-Jesús, A., & Leal‐Galicia, P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073028 · Cited by 46 · see citing works

Chronic retinoic acid treatment suppresses adult hippocampal neurogenesis, in close correlation with depressive-like behavior

Hu, P., Wang, Y., Liu, J., Meng, F., Qi, X., Chen, L., van Dam, A., Joëls, M., Lucassen, P. J., & Zhou, J. (2016) · Hippocampus · doi:10.1002/hipo.22574 · Cited by 39 · see citing works

Spinal cord injury drives chronic brain changes

Labombarda, F., & Jure, I. (2017) · Neural Regeneration Research · doi:10.4103/1673-5374.211177 · Cited by 39 · see citing works

Cyanidin-related antidepressant-like efficacy requires PI3K/AKT/FoxG1/FGF-2 pathway modulated enhancement of neuronal differentiation and dendritic maturation

Shan, X., Chen, J., Dai, S., Wang, J., Huang, Z., Lv, Z., Wang, Q., & Wu, Q. (2020) · Phytomedicine · doi:10.1016/j.phymed.2020.153269 · Cited by 39 · see citing works

Decreasing auditory input induces neurogenesis impairment in the hippocampus

Kurioka, T., Mogi, S., & Yamashita, T. (2021) · Scientific Reports · doi:10.1038/s41598-020-80218-z · Cited by 37 · see citing works

Ninjinyoeito Improves Behavioral Abnormalities and Hippocampal Neurogenesis in the Corticosterone Model of Depression

Murata, K., Fujita, N., Takahashi, R., & Inui, A. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01216 · Cited by 36 · see citing works

The ‘Yin’ and the ‘Yang’ of the kynurenine pathway: excitotoxicity and neuroprotection imbalance in stress-induced disorders

Barone, P. R. (2019) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000477 · Cited by 33 · see citing works

The social instability stress paradigm in rat and mouse: A systematic review of protocols, limitations, and recommendations

Koert, A., Ploeger, A., Bockting, C., Schmidt, M. V., Lucassen, P. J., Schrantee, A., & Mul, J. D. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100410 · Cited by 33 · see citing works

Neurogenesis in the adult hypothalamus: A distinct form of structural plasticity involved in metabolic and circadian regulation, with potential relevance for human pathophysiology

Sharif, A., Fitzsimons, C. P., & Lucassen, P. J. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819975-6.00006-6 · Cited by 31 · see citing works

Hormonal Regulation of Mammalian Adult Neurogenesis: A Multifaceted Mechanism

Jorgensen, C., & Wang, Z. (2020) · Biomolecules · doi:10.3390/biom10081151 · Cited by 34 · see citing works

Curcumin reverses cognitive deficits through promoting neurogenesis and synapse plasticity via the upregulation of PSD95 and BDNF in mice

Li, G., Wu, Q., Wang, C., Deng, P., Li, J., Zhai, Z., & Li, Y. (2025) · Scientific Reports · doi:10.1038/s41598-024-82571-9 · Cited by 31 · see citing works

Mesenchymal stem cells ( MSCs ) and MSC ‐derived exosomes in animal models of central nervous system diseases: Targeting the NLRP3 inflammasome

Nazari, S., Pourmand, S. M., Motevaseli, E., & Hassanzadeh, G. (2023) · IUBMB Life · doi:10.1002/iub.2759 · Cited by 28 · see citing works

Early‐life stress diminishes the increase in neurogenesis after exercise in adult female mice

Abbink, M. R., Naninck, E. F. G., Lucassen, P. J., & Kőrösi, A. (2017) · Hippocampus · doi:10.1002/hipo.22745 · Cited by 29 · see citing works

Spinal Cord Injury Leads to Hippocampal Glial Alterations and Neural Stem Cell Inactivation

Jure, I., Nicola, A. F. D., Encinas, J. M., & Labombarda, F. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-00900-8 · Cited by 25 · see citing works

Low intensity, long term exposure to tobacco smoke inhibits hippocampal neurogenesis in adult mice

Csabai, D., Csekő, K., Szaiff, L., Varga, Z., Miseta, A., Helyes, Z., & Czéh, B. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.01.022 · Cited by 25 · see citing works

Retinoic acid-pretreated Wharton’s jelly mesenchymal stem cells in combination with triiodothyronine improve expression of neurotrophic factors in the subventricular zone of the rat ischemic brain injury

Sabbaghziarani, F., Mortezaee, K., Akbari, M., Kashani, I. R., Soleimani, M., Moini, A., Nejad, N. A., Zendedel, A., & Hassanzadeh, G. (2016) · Metabolic Brain Disease · doi:10.1007/s11011-016-9897-8 · Cited by 24 · see citing works

Blast-induced hearing loss suppresses hippocampal neurogenesis and disrupts long term spatial memory

Manohar, S., Adler, H. J., Chen, G., & Salvi, R. (2020) · Hearing Research · doi:10.1016/j.heares.2020.108022 · Cited by 23 · see citing works

Hippocampal neuropathology in suicide: Gaps in our knowledge and opportunities for a breakthrough

Zhang, L., Lucassen, P. J., Salta, E., Verhaert, P. D. E. M., & Swaab, D. F. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.12.023 · Cited by 22 · see citing works

Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood–brain barrier disruption

Hu, H., Xue, Y., He, Y., Duan, C., & Sun, N. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02569-w · Cited by 20 · see citing works

Time-lapse imaging reveals highly dynamic structural maturation of postnatally born dentate granule cells in organotypic entorhino-hippocampal slice cultures

Radic, T., Jungenitz, T., Singer, M., Beining, M., Cuntz, H., Vlachos, A., Deller, T., & Schwarzacher, S. W. (2017) · Scientific Reports · doi:10.1038/srep43724 · Cited by 24 · see citing works

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders

Chen, L., Li, Z., Wang, W., Zhou, Y., Li, W., & Wang, Y. (2025) · Stem Cell Reports · doi:10.1016/j.stemcr.2025.102600 · Cited by 22 · see citing works

IGF1 Gene Therapy Reversed Cognitive Deficits and Restored Hippocampal Alterations After Chronic Spinal Cord Injury

Jure, I., Lockhart, E. F., Nicola, A. F. D., Bellini, M. J., & Labombarda, F. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02545-0 · Cited by 20 · see citing works

The gut microbiome and adult hippocampal neurogenesis: A new focal point for epilepsy?

Dohm-Hansen, S., Donoso, F., Lucassen, P. J., Clarke, G. A., & Nolan, Y. M. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105746 · Cited by 20 · see citing works

Booting up the organism during development: Pre-behavioral functions of the vertebrate brain in guiding body morphogenesis

Herrera‐Rincon, C., & Levin, M. G. (2018) · Communicative & Integrative Biology · doi:10.1080/19420889.2018.1433440 · Cited by 20 · see citing works

Neural stem cells persist to generate new neurons in the hippocampus of adult and aged human brain – Fiction or accurate?

Zanirati, G., Shetty, P. A., & Shetty, A. K. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102133 · Cited by 19 · see citing works

Polygala japonica Houtt. reverses depression-like behavior and restores reduced hippocampal neurogenesis in chronic stress mice

Zhou, Y., Ma, C., Li, B., & Sun, C. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.01.133 · Cited by 19 · see citing works

Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke

Sabbaghziarani, F., Mortezaee, K., Akbari, M., Kashani, I. R., Soleimani, M., Hassanzadeh, G., & Zendedel, A. (2017) · Cell Biochemistry and Function · doi:10.1002/cbf.3244 · Cited by 19 · see citing works

Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy

Arshad, M. N., Oppenheimer, S., Jeong, J., Büyükdemirtaş, B., & Naegele, J. R. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105879 · Cited by 18 · see citing works

Pubertal immune stress transiently alters spatial memory processes in adulthood

Kolmogorova, D., Paré, C., Kostuck, S., Hudson, E. C., Lebel, N., Houlding-Braunberger, E., Gregory, J. G., & Ismail, N. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.12.224 · Cited by 18 · see citing works

Supplementation of Taurine Insulates Against Oxidative Stress, Confers Neuroprotection and Attenuates Memory Impairment in Noise Stress Exposed Male Wistar Rats

Haider, S., Sajid, I., Batool, Z., Madiha, S., Sadir, S., Kamil, N. R., Liaquat, L., Ahmad, S., Tabassum, S., & Khaliq, S. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03127-7 · Cited by 18 · see citing works

Machine Learning Prediction of Estimated Risk for Bipolar Disorders Using Hippocampal Subfield and Amygdala Nuclei Volumes

Huth, F., Tozzi, L., Marxen, M., Riedel, P., Bröckel, K. L., Martini, J., Berndt, C., Sauer, C., Vogelbacher, C., Jansen, A., et al. (2023) · Brain Sciences · doi:10.3390/brainsci13060870 · Cited by 17 · see citing works

Treadmill exercise prevents stress-induced anxiety-like behaviors via enhancing the excitatory input from the primary motor cortex to the thalamocortical circuit

Luo, Z., Chen, J., Liu, Y., Dai, Y., Gao, H., Zhang, B., Ou, H., So, K., Wei, J., & Zhang, L. (2025) · Nature Communications · doi:10.1038/s41467-025-56258-2 · Cited by 17 · see citing works

A sex-dependent delayed maturation of visual plasticity induced by adverse experiences in early childhood

Liu, Y., Wang, Z., Zhang, X., Li, S., Wu, W., Li, X., & Yang, Y. (2020) · Neurobiology of Stress · doi:10.1016/j.ynstr.2020.100256 · Cited by 16 · see citing works

Impact of neonatal anoxia and hypothermic treatment on development and memory of rats

Matsuda, V. D. V., Bustelo, M., Motta‐Teixeira, L. C., Ikebara, J. M., Cardoso, D. S., Machado‐Nils, A. V., Lee, V. Y., Diccini, I., Arruda, B. P., Martins, P. P., et al. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113691 · Cited by 17 · see citing works

Restricted vs. unrestricted wheel running in mice: Effects on brain, behavior and endocannabinoids

Biedermann, S. V., Auer, M. K., Bîndilă, L., Ende, G., Lutz, B., Weber‐Fahr, W., Gass, P., & Fuß, J. (2016) · Hormones and Behavior · doi:10.1016/j.yhbeh.2016.09.007 · Cited by 15 · see citing works

Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models

Yu, Z., Kong, D., Liang, Y., Zhao, X., & Du, G. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.002 · Cited by 15 · see citing works

Systematic review of genome-wide association studies of anxiety disorders and neuroticism

van der Walt, K., Campbell, M. L., Stein, D. J., & Dalvie, S. (2022) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2022.2099970 · Cited by 16 · see citing works

Stress, mental disorder and ketamine as a novel, rapid acting treatment

Dutton, M., Can, A., Lagopoulos, J., & Hermens, D. F. (2022) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2022.09.006 · Cited by 15 · see citing works

Targeting the Oxytocin System to Ameliorate Early Life Depressive-Like Behaviors in Maternally-Separated Rats

Abdelwahab, L. A., Galal, O., El‐Rahman, S. S. A., El-Brairy, A. I., Khattab, M. M., & El-Khatib, A. S. (2021) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b21-00247 · Cited by 13 · see citing works

Higher Serum C Reactive Protein Determined C Reactive Protein Single-Nucleotide Polymorphisms Are Involved in Inherited Depression

Wang, S., Zhong, H., Lu, M., Song, G., Zhang, X., Lin, M., Yang, S., & Qian, M. (2018) · Psychiatry Investigation · doi:10.30773/pi.2018.04.03.2 · Cited by 13 · see citing works

Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists

Park, J. Y., Chae, S., Kim, C. S., Kim, Y. J., Yi, H. J., Han, E.-J., Joo, Y., Hong, S., Yun, J. W., Kim, H., et al. (2019) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2019.23.6.427 · Cited by 12 · see citing works

Training on an Appetitive Trace-Conditioning Task Increases Adult Hippocampal Neurogenesis and the Expression of Arc, Erk and CREB Proteins in the Dorsal Hippocampus

Tripathi, S., Verma, A., & Jha, S. K. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00089 · Cited by 12 · see citing works

Interaction Between Neurogenic Stimuli and the Gene Network Controlling the Activation of Stem Cells of the Adult Neurogenic Niches, in Physiological and Pathological Conditions

Ceccarelli, M., D’Andrea, G., Micheli, L., & Tirone, F. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00211 · Cited by 11 · see citing works

Sex-specific and developmental effects of early life adversity on stress reactivity are rescued by postnatal knockdown of 5-HT1A autoreceptors

Dixon, R. S., Malave, L. B., Thompson, R., Wu, S. S., Li, Y., Sadik, N., & Anacker, C. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01999-9 · Cited by 11 · see citing works

Early Life Stress- and Sex-Dependent Effects on Hippocampal Neurogenesis

Lucassen, P. J., Kőrösi, A., Krugers, H. J., & Oomen, C. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802175-0.00013-9 · Cited by 10 · see citing works

Stress, hippocampal neurogenesis and cognition: functional correlations

Lucassen, P. J., & Oomen, C. A. (2016) · Frontiers in Biology · doi:10.1007/s11515-016-1412-4 · Cited by 20 · see citing works

Adult Neurogenesis, Chronic Stress and Depression

Lucassen, P. J., Oomen, C. A., Schouten, M., Encinas, J. M., & Fitzsimons, C. P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801977-1.00008-8 · Cited by 15 · see citing works

Adult Neurogenesis and Stress

Briones, B. A., & Gould, E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813146-6.00007-2 · Cited by 9 · see citing works

Stress in early life inhibits neurogenesis in adulthood

Karten, Y. J. G., Olariu, A., & Cameron, H. A. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.01.009 · Cited by 108 · see citing works