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The cause of neuronal degeneration in Alzheimer’s disease
Open accessAbstract
Alzheimer's disease is associated with a specific pattern of pathological changes in the brain that result in neurodegeneration and the progressive development of dementia. Pathological hallmarks common to the disease include beta-amyloid plaques, dystrophic neurites associated with plaques and neurofibrillary tangles within nerve cell bodies. The exact relationship between these pathological features has been elusive, although it is clear that beta-amyloid plaques precede neurofibrillary tangles in neocortical areas. Examination of the brains of individuals in the preclinical stage of the disease have shown that the earliest form of neuronal pathology associated with beta-amyloid plaques resembles the cellular changes that follow structural injury to axons. Thus, the development of beta-amyloid plaques in the brain may cause physical damage to axons, and the abnormally prolonged stimulation of the neuronal response to this kind of injury ultimately results in the profound cytoskeletal alterations that underlie neurofibrillary pathology and neurodegeneration. Therapeutically, inhibition of the neuronal reaction to physical trauma may be a useful neuroprotective strategy in the earliest stages of Alzheimer's disease.
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“The pathology of AD manifests with degeneration of the neurons, along with loss of synapses in the cortex, the hippocampus, and the subcortical structures [12].”
From The Multifaceted Role of Neuroprotective Plants in Alzheimer’s Disease Treatment (2022) · cites this paper as [12]
Citations
Cites
Neuropathological stageing of Alzheimer-related changes.
Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429
Alzheimer's disease: the amyloid cascade hypothesis
Hardy, J. A., & Higgins, G. A. (1992) · Science · doi:10.1126/science.1566067 · Cited by 7,484
Glenner, G. G., & Wong, C. W. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(84)80190-4 · Cited by 5,404
Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., Belle, G. V., Berg, L., et al. (1991) · Neurology · doi:10.1212/wnl.41.4.479 · Cited by 4,961
Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L., & Beyreuther, K. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.12.4245 · Cited by 4,431
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
Mahley, R. W. (1988) · Science · doi:10.1126/science.3283935 · Cited by 4,028
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins
Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6448 · Cited by 3,506
Degeneration and Regeneration of the Nervous System.
(1929) · JAMA · doi:10.1001/jama.1929.02710220063037 · Cited by 2,908
The molecular pathology of Alzheimer's disease
Selkoe, D. J. (1991) · Neuron · doi:10.1016/0896-6273(91)90052-2 · Cited by 2,708
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
Yan, S. D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., et al. (1996) · Nature · doi:10.1038/382685a0 · Cited by 2,012
Amyloid β-peptide is produced by cultured cells during normal metabolism
Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B., et al. (1992) · Nature · doi:10.1038/359322a0 · Cited by 1,921
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
Corder, E. H., Saunders, A. M., Risch, N. J., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Rimmler, J. B., Locke, P. A., Conneally, P. M., Schmader, K. E., et al. (1994) · Nature Genetics · doi:10.1038/ng0694-180 · Cited by 1,920
Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease
Gómez-Isla, T., Price, J. L., McKeel Jr., D. W., Morris, J. C., Growdon, J. H., & Hyman, B. T. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-14-04491.1996 · Cited by 1,796
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schiossmacher, M., Whaley, J., Swindlehurst, C., et al. (1992) · Nature · doi:10.1038/359325a0 · Cited by 1,731
Mattson, M. P., Cheng, B., Davis, D. G., Bryant, K., Lieberburg, I. M., & Rydel, R. E. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-02-00376.1992 · Cited by 1,633
Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H., Pericak-Vance, M. A., Goldgaber, D., & Roses, A. D. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.20.9649 · Cited by 1,525
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
Sturchler-Pierrat, C., Abramowski, D., Duke, M., Wiederhold, K.-H., Mistl, C., Rothacher, S., Ledermann, B., Bürki, K., Frey, P., Paganetti, P. A., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13287 · Cited by 1,507
Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing
Shoji, M., Golde, T. E., Ghiso, J., Cheung, T. T., Estus, S., Shaffer, L. M., Cai, X.-D., McKay, D. M., Tintner, R., Frangione, B., et al. (1992) · Science · doi:10.1126/science.1439760 · Cited by 1,447
A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau
Lee, V. M.-Y., Balin, B. J., Otvos, L., & Trojanowski, J. Q. (1991) · Science · doi:10.1126/science.1899488 · Cited by 1,418
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state
Pike, C., Burdick, D., Walencewicz, A., Glabe, C., & Cotman, C. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-04-01676.1993 · Cited by 1,417
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.
Lorenzo, A., & Yankner, B. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.25.12243 · Cited by 1,324
Occurrence of neuropathological changes and dementia of Alzheimer’s disease in Down’s syndrome
Wisniewski, K. E., Wisniewski, H. M., & Wen, G. Y. (1985) · Annals of Neurology · doi:10.1002/ana.410170310 · Cited by 1,159
Sternberger, L. A., & Sternberger, N. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.19.6126 · Cited by 1,158
The Axon Reaction: A Review of the Principal Features of Perikaryal Responses to Axon Injury
Lieberman, A. R. (1971) · International review of neurobiology · doi:10.1016/s0074-7742(08)60183-x · Cited by 1,115
Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
William Rebeck, G., Reiter, J. S., Strickland, D. K., & Hyman, B. T. (1993) · Neuron · doi:10.1016/0896-6273(93)90070-8 · Cited by 1,107
Hensley, K., Carney, J. M., Mattson, M. P., Aksenova, M., Harris, M., Wu, J. F., Floyd, R. A., & Butterfield, D. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3270 · Cited by 1,086
Oxidative damage to mitochondrial DNA is increased in Alzheimer’s disease
Mecocci, P., MacGarvey, U., & Beal, M. F. (1994) · Annals of Neurology · doi:10.1002/ana.410360510 · Cited by 1,037
Goedert, M., Jakes, R., Spillantini, M. G., Hasegawa, M., Smith, M. J., & Crowther, R. A. (1996) · Nature · doi:10.1038/383550a0 · Cited by 1,036
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.
Loo, D. T., Copani, A., Pike, C. J., Whittemore, E. R., Walencewicz, A. J., & Cotman, C. W. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7951 · Cited by 1,029
Pearson, R. C., Esiri, M. M., Hiorns, R. W., Wilcock, G. K., & Powell, T. P. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.13.4531 · Cited by 987
A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease
Kawas, C. H., Resnick, S. M., Morrison, A., Brookmeyer, R., Corrada, M. M., Zonderman, A. B., Bacal, C., Lingle, D. D., & Metter, E. J. (1997) · Neurology · doi:10.1212/wnl.48.6.1517 · Cited by 967
Mechanisms of Neuronal Degeneration in Alzheimer's Disease
Yankner, B. A. (1996) · Neuron · doi:10.1016/s0896-6273(00)80115-4 · Cited by 953
Wischik, C. M., Novak, M., Thøgersen, H. C., Edwards, P. C., Runswick, M. J., Jakes, R., Walker, J. E., Milstein, C., Roth, M., & Klug, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.12.4506 · Cited by 939
Bramblett, G. T., Goedert, M., Jakes, R., Merrick, S. E., Trojanowski, J. Q., & Lee, V. M. Y. (1993) · Neuron · doi:10.1016/0896-6273(93)90057-x · Cited by 903
Ma, J., Yee, A., Brewer, H. B., Das, S., & Potter, H. (1994) · Nature · doi:10.1038/372092a0 · Cited by 871
In vitro aging of ß-amyloid protein causes peptide aggregation and neurotoxicity
Pike, C. J., Walencewicz, A. J., Glabe, C. G., & Cotman, C. W. (1991) · Brain Research · doi:10.1016/0006-8993(91)91553-d · Cited by 841
Price, J. L., Davis, P. B., Morris, J. C., & White, D. L. (1991) · Neurobiology of Aging · doi:10.1016/0197-4580(91)90006-6 · Cited by 818
Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid
Wisniewski, T., & Frangione, B. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90444-c · Cited by 802
Differential Effects of Apolipoproteins E3 and E4 on Neuronal Growth in Vitro
Nathan, B. P., Bellosta, S., Sanan, D. A., Weisgraber, K. H., Mahley, R. W., & Pitas, R. E. (1994) · Science · doi:10.1126/science.8171342 · Cited by 795
Tang, M.-X. (1998) · JAMA · doi:10.1001/jama.279.10.751 · Cited by 771
The Pathogenesis of Senile Plaques
DICKSON, D. W. (1997) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199704000-00001 · Cited by 753
Alzheimer's Disease: A Central Role for Amyloid
Selkoe, D. J. (1994) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199409000-00003 · Cited by 752
de Waegh, S. M., Lee, V. M. ‐., & Brady, S. T. (1992) · Cell · doi:10.1016/0092-8674(92)90183-d · Cited by 743
Rogers, J., Luber-Narod, J., Styren, S. D., & Civin, W. H. (1988) · Neurobiology of Aging · doi:10.1016/s0197-4580(88)80079-4 · Cited by 743
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
Koo, E. H., Sisodia, S. S., Archer, D. R., Martin, L. J., Weidemann, A., Beyreuther, K., Fischer, P., Masters, C. L., & Price, D. L. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1561 · Cited by 733
Neurofilament gene expression: a major determinant of axonal caliber.
Hoffman, P. N., Cleveland, D. W., Griffin, J. W., Landes, P. W., Cowan, N. J., & Price, D. L. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.10.3472 · Cited by 719
Uchida, Y., Takio, K., Titani, K., Ihara, Y., & Tomonaga, M. (1991) · Neuron · doi:10.1016/0896-6273(91)90272-2 · Cited by 703
Association of apolipoprotein E polymorphism with outcome after head injury
Teasdale, G. M., Nicoll, J. A. R., Murray, G. D., & Fiddes, M. (1997) · The Lancet · doi:10.1016/s0140-6736(97)04318-3 · Cited by 683
Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing
Jordan, B. D. (1997) · JAMA · doi:10.1001/jama.278.2.136 · Cited by 665
Berg, L., McKeel, D. W., Miller, J. P., Storandt, M., Rubin, E. H., Morris, J. C., Baty, J., Coats, M., Norton, J., Goate, A. M., et al. (1998) · Archives of Neurology · doi:10.1001/archneur.55.3.326 · Cited by 657
Arriagada, P. V., Marzloff, K., & Hyman, B. T. (1992) · Neurology · doi:10.1212/wnl.42.9.1681 · Cited by 638
Apolipoprotein E in animal models of CNS injury and in alzheimer's disease
Poirier, J. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90156-2 · Cited by 637
β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
Koh, J., Yang, L. L., & Cotman, C. W. (1990) · Brain Research · doi:10.1016/0006-8993(90)91355-k · Cited by 617
Immunohistochemical evidence for apoptosis in Alzheimer's disease.
Su, J., Anderson, A., Cummings, B. J., & Cotman, C. (1994) · NeuroReport · doi:10.1097/00001756-199412000-00031 · Cited by 607
Morris, J. C., Storandt, M., McKeel, D. W., Rubin, E. H., Price, J. L., Grant, E. A., & Berg, L. (1996) · Neurology · doi:10.1212/wnl.46.3.707 · Cited by 603
Mayeux, R., Ottman, R., Maestre, G., Ngai, C., Tang, M.-X., Ginsberg, H., Chun, M., Tycko, B., & Shelanski, M. (1995) · Neurology · doi:10.1212/wnl.45.3.555 · Cited by 590
Crystal, H., Dickson, D., Fuld, P., Masur, D., Scott, R., Mehler, M., Masdeu, J., Kawas, C., Aronson, M., & Wolfson, L. (1988) · Neurology · doi:10.1212/wnl.38.11.1682 · Cited by 586
Lewis, D., Campbell, M., Terry, R., & Morrison, J. (1987) · The Journal of Neuroscience · doi:10.1523/jneurosci.07-06-01799.1987 · Cited by 578
A Mechanistic Analysis of Nondisruptive Axonal Injury: A Review
Maxwell, W. L., Povlishock, J. T., & Graham, D. I. (1997) · Journal of Neurotrauma · doi:10.1089/neu.1997.14.419 · Cited by 564
Arispe, N. J., Pollard, H. B., & Rojas, E. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.22.10573 · Cited by 561
Lyras, L., Cairns, N. J., Jenner, A., Jenner, P., & Halliwell, B. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.68052061.x · Cited by 531
Aging renders the brain vulnerable to amyloid β-protein neurotoxicity
Guela, C., Wu, C.-K., Saroff, D., Lorenzo, A., Yuan, M., & Yankner, B. A. (1998) · Nature Medicine · doi:10.1038/nm0798-827 · Cited by 520
The occult aftermath of boxing.
Roberts, G. W., Allsop, D., & Bruton, C. (1990) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.53.5.373 · Cited by 518
Neocortical Neurofibrillary Tangles Correlate With Dementia Severity in Alzheimer's Disease
Bierer, L. M., Hof, P. R., Purohit, D. P., Carlin, L., Schmeidler, J., Davis, K. L., & Perl, D. P. (1995) · Archives of Neurology · doi:10.1001/archneur.1995.00540250089017 · Cited by 514
The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice
LaFerla, F. M., Tinkle, B. T., Bieberich, C. J., Haudenschild, C. C., & Jay, G. (1995) · Nature Genetics · doi:10.1038/ng0195-21 · Cited by 513
Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion
Taupin, V., Toulmond, S., Serrano, A., Bénavidès, J., & Zavala, F. (1993) · Journal of Neuroimmunology · doi:10.1016/0165-5728(93)90008-m · Cited by 512
Povlishock, J. T., & Christman, C. W. (1995) · Journal of Neurotrauma · doi:10.1089/neu.1995.12.555 · Cited by 499
Rosengren, L. E., Karlsson, J., Karlsson, J., Persson, L. I., & Wikkelsø, C. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67052013.x · Cited by 499
Irizarry, M. C., Soriano, F., McNamara, M., Page, K. J., Schenk, D., Games, D., & Hyman, B. T. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-18-07053.1997 · Cited by 497
Evidence for Apoptotic Cell Death in Alzheimer's Disease
Smale, G., Nichols, N. R., Brady, D. R., Finch, C. E., & Horton, W. E. (1995) · Experimental Neurology · doi:10.1006/exnr.1995.1025 · Cited by 495
Interleukin‐6 and α‐2‐macroglobulin indicate an acute‐phase state in Alzheimer's disease cortices
Bauer, J., Strauss, S., Schreiter-Gasser, U., Ganter, U., Schlegel, P., Witt, I., Yolk, B., & Berger, M. (1991) · FEBS Letters · doi:10.1016/0014-5793(91)80737-n · Cited by 483
Morris, J. C., McKeel, D. W., Storandt, M., Rubin, E. H., Price, J. L., Grant, E. A., Ball, M. J., & Berg, L. (1991) · Neurology · doi:10.1212/wnl.41.4.469 · Cited by 473
Mann, D. M. A., & Esiri, M. M. (1989) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(89)90019-1 · Cited by 471
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
Lassmann, H., Bancher, C., Breitschopf, H., Węgiel, J., Bobinski, M., Jellinger, K. A., & Wísniewski, H. M. (1994) · Acta Neuropathologica · doi:10.1007/bf00294257 · Cited by 464
Radical AGEing in Alzheimer's disease
Smith, M. A., Sayre, L. M., Monnier, V. M., & Perry, G. L. (1995) · Trends in Neurosciences · doi:10.1016/0166-2236(95)93897-7 · Cited by 462
What is the signal for chromatolysis?
Cragg, B. G. (1970) · Brain Research · doi:10.1016/0006-8993(70)90345-8 · Cited by 453
Goedert, M., Jakes, R., Crowther, R. A., Six, J., Lübke, U., Vandermeeren, M., Cras, P., Trojanowski, J. Q., & Lee, V. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.11.5066 · Cited by 446
Apolipoprotein E-ε4 genotype predicts a poor outcome in survivors of traumatic brain injury
Friedman, G., Froom, P., Sazbon, L., Grinblatt, I., Shochina, M., Tsenter, J., Babaey, S., Yehuda, A. B., & Groswasser, Z. (1999) · Neurology · doi:10.1212/wnl.52.2.244 · Cited by 437
Wolozin, B. L., Iwasaki, K., Vito, P., Ganjei, J. K., Lacaná, E., Sunderland, T., Zhao, B., Kusiak, J. W., Wasco, W., & D'adamio, L. (1996) · Science · doi:10.1126/science.274.5293.1710 · Cited by 425
The Role of Inflammation and Cytokines in Brain Injury
Arvin, B. M., Neville, L. F., Barone, F. C., & Feuerstein, G. (1996) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(95)00026-7 · Cited by 417
Glial cytokines in Alzheimer's disease: Review and pathogenic implications
Mrak, R. E., Sheng, J. G., & Griffin, W. S. T. (1995) · Human Pathology · doi:10.1016/0046-8177(95)90001-2 · Cited by 415
Epidemiology of Dementia and Alzheimer's Disease
Hendrie, H. C. (1998) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-199821001-00002 · Cited by 411
Butterfield, D. A., Hensley, K., Harris‐White, M. E., Mattson, M. P., & Carney, J. M. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.1508 · Cited by 404
Masliah, E., Sisk, A., Mallory, M. E., Mucke, L., Schenk, D., & Games, D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-18-05795.1996 · Cited by 389
Lampert, P. W. (1967) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-196707000-00001 · Cited by 387
Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques.
Dickson, D. W., Farlo, J., Davies, P., Crystal, H., Fuld, P. A., & Yen, S. H. (1988) · PubMed Central · Cited by 383
Activation of the classical complement pathway in brain tissue of Alzheimer patients
McGeer, P. L., Akiyama, H., Itagaki, S., & McGeer, E. G. (1989) · Neuroscience Letters · doi:10.1016/0304-3940(89)90843-4 · Cited by 383
Delayed Maturation of Regenerating Myelinated Axons in Mice Lacking Neurofilaments
Zhu, Q., Couillard‐Després, S., & Julien, J. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6654 · Cited by 378
Campbell, M. J., & Morrison, J. H. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902820204 · Cited by 370
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease
Davies, L., Wolska, B., Hilbich, C., Multhaup, G., Martins, R. N., Simms, G., Beyreuther, K. T., & Masters, C. L. (1988) · Neurology · doi:10.1212/wnl.38.11.1688 · Cited by 369
Hof, P. R., Morrison, J. H., & Cox, K. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.903010105 · Cited by 365
Neuritic pathology and dementia in alzheimer's disease
McKee, A. C., Kosik, K. S., & Kowall, N. W. (1991) · Annals of Neurology · doi:10.1002/ana.410300206 · Cited by 358
Weldon, D. T., Rogers, S. D., Ghilardi, J. R., Finke, M. P., Cleary, J. P., O’Hare, E., Esler, W. P., Maggio, J. E., & Mantyh, P. W. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-06-02161.1998 · Cited by 348
Dragunow, M., Faull, R. L. M., Lawlor, P. A., Beilharz, E. J., Singleton, K., Walker, E. B., & Mee, E. T. (1995) · Neuroreport · doi:10.1097/00001756-199505090-00026 · Cited by 342
Apoptosis mediated neurotoxicity induced by chronic application of β amyloid fragment 25–35
Forloni, G., Chiesa, R., Smiroldo, S., Verga, L., Salmona, M., Tagliavini, F., & Angeretti, N. (1993) · Neuroreport · doi:10.1097/00001756-199305000-00015 · Cited by 341
Closed Head Injury Triggers Early Production of TNFα and IL-6 by Brain Tissue
Shohami, E., Novikov, M., Bass, R., Yamin, A., & Gallily, R. (1994) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1994.76 · Cited by 341
Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease.
Joachim, C. L., Morris, J. H., & Selkoe, D. J. (1989) · PubMed Central · Cited by 335
Paradis, E., Douillard, H., Koutroumanis, M., Goodyer, C. G., & LeBlanc, A. C. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-23-07533.1996 · Cited by 333
Yaar, M., Zhai, S., Pilch, P. F., Doyle, S. M., Eisenhauer, P. B., Fine, R. E., & Gilchrest, B. A. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119772 · Cited by 331
Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.
Cras, P. P., Kawai, M., Lowery, D. E., Gonzalez‐DeWhitt, P. A., Greenberg, B., & Perry, G. L. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.17.7552 · Cited by 314
Marked changes in mitochondrial DNA deletion levels in Alzheimer brains
Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., McKee, A. C., Beal, M. F., Graham, B. H., & Wallace, D. C. (1994) · Genomics · doi:10.1006/geno.1994.1525 · Cited by 309
Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease
de la Monte, S. M., Sohn, Y. K., & Wands, J. R. (1997) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(97)00131-7 · Cited by 307
Cummings, B. J., Pike, C. J., Shankle, R., & Cotman, C. W. (1996) · Neurobiology of Aging · doi:10.1016/s0197-4580(96)00170-4 · Cited by 305
Hof, P. R., & Morrison, J. H. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.903010106 · Cited by 294
Inflammatory mechanisms in Alzheimer's disease
Eikelenboom, P., Zhan, S., van Gool, W. A., & Allsop, D. (1994) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(94)90057-4 · Cited by 291
Fineman, I., Hovda, D. A., Smith, M. L., Yoshino, A., & Becker, D. P. (1993) · Brain Research · doi:10.1016/0006-8993(93)90064-t · Cited by 287
Mufson, E. J., Bothwell, M. A., & Kordower, J. H. (1989) · Experimental Neurology · doi:10.1016/0014-4886(89)90124-6 · Cited by 279
Apolipoprotein E allele ∈4, dementia, and cognitive decline in a population sample
Henderson, A. S., Jorm, A. F., Korten, A. E., Christensen, H. M., Jacomb, P. A., Easteal, S., Croft, L., & Mackinnon, A. J. (1995) · The Lancet · doi:10.1016/s0140-6736(95)92405-1 · Cited by 272
Localization of Alzheimer βA4 amyloid precursor protein at central and peripheral synaptic sites
SCHUBERT, W. J., Prior, R., Weidemann, A., Dircksen, H., Multhaup, G., Masters, C. L., & Beyreuther, K. T. (1991) · Brain Research · doi:10.1016/0006-8993(91)91532-6 · Cited by 272
Ehlers, M., Fung, E. T., O’Brien, R., & Huganir, R. L. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-02-00720.1998 · Cited by 272
THE ROLE OF ANTI-INFLAMMATORY DRUGS IN THE PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE
Breitner, J. C. S. (1996) · Annual Review of Medicine · doi:10.1146/annurev.med.47.1.401 · Cited by 263
Image analysis of β-amyloid load in Alzheimer's disease and relation to dementia severity
Cummings, B. J., & Cotman, C. W. (1995) · The Lancet · doi:10.1016/s0140-6736(95)92053-6 · Cited by 262
Webster, S. D., Lue, L., Brachova, L., Tenner, A. J., McGeer, P. L., Terai, K., Walker, D. G., Bradt, B. M., Cooper, N. R., & Rogers, J. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00042-0 · Cited by 258
Burgoyne, R. D. (1992) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(92)90511-7 · Cited by 257
Alzheimer's disease: a re-examination of the amyloid hypothesis
Neve, R. L., & Robakis, N. K. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01168-5 · Cited by 255
Pettus, E. H., & Povlishock, J. T. (1996) · Brain Research · doi:10.1016/0006-8993(96)00113-8 · Cited by 250
Toulmond, S., & Rothwell, N. J. (1995) · Brain Research · doi:10.1016/0006-8993(94)01343-g · Cited by 248
Bax Protein Expression Is Increased in Alzheimerʼs Brain
Su, J. H., Deng, G., & Cotman, C. W. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199701000-00009 · Cited by 239
Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain
Pant, H. C. (1988) · Biochemical Journal · doi:10.1042/bj2560665 · Cited by 238
Down patients: Extracellular preamyloid deposits precede neuritic degeneration and senile plaques
Giaccone, G., Tagliavini, F., Linoli, G., Bouras, C., Frigerio, L., Frangione, B., & Bugiani, O. (1989) · Neuroscience Letters · doi:10.1016/0304-3940(89)90169-9 · Cited by 231
Diffuse axonal injury in head trauma.
Blumbergs, P. C., Jones, N. R., & North, J. B. (1989) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.52.7.838 · Cited by 230
In vivo neurotoxicity of beta-amyloid [β(1–40)] and the β(25–35) fragment
Kowall, N. W., McKee, A. C., Yankner, B. A., & Beal, M. F. (1992) · Neurobiology of Aging · doi:10.1016/0197-4580(92)90053-z · Cited by 223
Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis
Mufson, E., Conner, J., & Kordower, J. (1995) · NeuroReport · doi:10.1097/00001756-199505090-00028 · Cited by 221
Alzheimer Disease: DMA Fragmentation Indicates Increased Neuronal Vulnerability, but not Apoptosis
Stadelmann, C., Brück, W., Bancher, C., Jellinger, K., & Lassmann, H. (1998) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199805000-00009 · Cited by 221
Grady, M., Mclaughlin, M., Christman, C. W., Valadka, A., Fligner, C., & Povlishock, J. (1993) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199303000-00007 · Cited by 217
Olichney, J. M., Hansen, L. A., Galasko, D., Saitoh, T., Hofstetter, C. R., Katzman, R., & Thal, L. J. (1996) · Neurology · doi:10.1212/wnl.47.1.190 · Cited by 216
Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.
Perry, G. L., Rizzuto, N., AUTILIO‐GAMBETTI, L., & Gambetti, P. L. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.11.3916 · Cited by 215
ULRICH, J. (1985) · Annals of Neurology · doi:10.1002/ana.410170309 · Cited by 212
Weiss, J. H., Pike, C. J., & Cotman, C. W. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62010372.x · Cited by 211
Alzheimer-like Changes in Microtubule-associated Protein Tau Induced by Sulfated Glycosaminoglycans
Hasegawa, M., Crowther, R. A., Jakes, R., & Goedert, M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.52.33118 · Cited by 207
Tokuda, T., Ikeda, S., Yanagisawa, N., Ihara, Y., & Glenner, G. G. (1991) · Acta Neuropathologica · doi:10.1007/bf00308813 · Cited by 202
Amyloid β Protein-(1–42) Forms Calcium-permeable, Zn2+-sensitive Channel
Rhee, S. K., Quist, A. P., & Lal, R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.22.13379 · Cited by 201
Neurofilaments: structure, metabolism and implications in disease.
Schlaepfer, W. W. (1987) · PubMed · Cited by 200
Nukina, N., Kosik, K. S., & Selkoe, D. J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.10.3415 · Cited by 199
Hof, P. R., & Morrison, J. H. (1991) · Experimental Neurology · doi:10.1016/0014-4886(91)90096-u · Cited by 196
Yan, H. Q., Banos, M. A., Herregodts, P., Hooghe, R. J., & Hooghe-Peters, E. L. (1992) · European Journal of Immunology · doi:10.1002/eji.1830221131 · Cited by 195
Correlation of axonal regeneration and slow component B in two branches of a single axon
Wujek, J., & Lasek, R. (1983) · Journal of Neuroscience · doi:10.1523/jneurosci.03-02-00243.1983 · Cited by 190
HOF, P. R., COX, K., Young, W. G., Celio, M. R., Rogers, J., & Morrison, J. H. (1991) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199107000-00006 · Cited by 188
Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease.
Mufson, E. J., & Kordower, J. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.2.569 · Cited by 188
Gonatas, N. K., Anderson, W., & Evangelista, I. (1967) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-196701000-00003 · Cited by 186
Tchélingérian, J., Quinonero, J., Booss, J., & Jacque, C. (1993) · Neuron · doi:10.1016/0896-6273(93)90312-f · Cited by 185
Povlishock, J. T., Marmarou, A., McIntosh, T. K., Trojanowski, J. Q., & Moroi, J. (1997) · PubMed · Cited by 185
Ksiȩżak-Reding, H., Dickson, D. W., Davies, P., & Yen, S. H. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.10.3410 · Cited by 181
Sheng, J. G., Mrak, R. E., & Griffin, W. S. T. (1995) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1995.tb01063.x · Cited by 181
The Neuroanatomy of Alzheimer's Disease
Pearson, R. C. A., & Powell, T. P. S. (1989) · Reviews in the Neurosciences · doi:10.1515/revneuro.1989.2.2.101 · Cited by 179
Johnson, S. A., Lampert-Etchells, M., Pasinetti, G. M., Rozovsky, I., & Finch, C. E. (1992) · Neurobiology of Aging · doi:10.1016/0197-4580(92)90086-d · Cited by 176
Erickson, J. C., Sewell, A. K., Jensen, L. T., Winge, D. R., & Palmiter, R. D. (1994) · Brain Research · doi:10.1016/0006-8993(94)91076-6 · Cited by 173
Yaghmai, A. A., & Povlishock, J. T. (1992) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199203000-00006 · Cited by 172
Calretinin-immunoreactive neocortical interneurons are unaffected in Alzheimer's disease
Hof, P. R., Nimchinsky, E. A., Celio, M. R., Bouras, C., & Morrison, J. H. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90504-e · Cited by 172
Electron microscopy of experimental degeneration in the avian optic tectum.
Gray, E. G., & Hamlyn, L. H. (1962) · PubMed · Cited by 167
Head Injury and Risk of Alzheimer's Disease by Apolipoprotein E Genotype
O'Meara, E. S., Kukull, W. A., Sheppard, L., Bowen, J. D., McCormick, W. C., Teri, L., Pfanschmidt, M., Thompson, J. D., Schellenberg, G. D., & Larson, E. B. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009290 · Cited by 165
Morrison, J. H., Lewis, D. A., Campbell, M. J., Huntley, G. W., Benson, D. L., & Bouras, C. (1987) · Brain Research · doi:10.1016/0006-8993(87)90914-0 · Cited by 164
Slowing of the rate of axonal regeneration during growth and maturation
Black, M. M., & Lasek, R. J. (1979) · Experimental Neurology · doi:10.1016/0014-4886(79)90188-2 · Cited by 163
Deller, T., & Frotscher, M. (1997) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00044-0 · Cited by 163
THE TOPOGRAPHY OF PLAQUES AND TANGLES IN DOWN'S SYNDROME PATIENTS OF DIFFERENT AGES
Mann, D. M. A., Yates, P. O., Marcyniuk, B., & Ravindra, C. (1986) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1986.tb00053.x · Cited by 161
ALZHEIMER'S DISEASE: PAIRED HELICAL FILAMENTS AND CYTOMEMBRANES
Gray, E. G., PAULA‐BARBOSA, M., & Roher, A. E. (1987) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1987.tb00174.x · Cited by 160
NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease
Higgins, G. A., & Mufson, E. J. (1989) · Experimental Neurology · doi:10.1016/0014-4886(89)90155-6 · Cited by 158
Phosphorylated Neurofilament Antigens in Neurofibrillary Tangles in Alzheimerʼs Disease
Cork, L. C., Sternberger, N. H., Sternberger, L. A., Casanova, M. F., Struble, R. G., & Price, D. L. (1986) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-198601000-00005 · Cited by 158
Lack of an association between apolipoprotein E ϵ4 and Alzheimer's disease in elderly nigerians
Osuntokun, B. O., Sahota, A. S., Ogunniyi, A. O., Gureje, O., Baiyewu, O., Adeyinka, A. O., Oluwole, S., Komolafe, O. O., Hall, K. S., Unverzagt, F. W., et al. (1995) · Annals of Neurology · doi:10.1002/ana.410380319 · Cited by 158
McKinney, R. A., Debanne, D., Gähwiler, B. H., & Thompson, S. M. (1997) · Nature Medicine · doi:10.1038/nm0997-990 · Cited by 157
Cras, P. P., Smith, M. A., Richey, P. L., Siedlak, S. L., Mulvihill, P., & Perry, G. L. (1995) · Acta Neuropathologica · doi:10.1007/bf00309621 · Cited by 156
Arai, H., Lee, V. M., Otvos, L. P., Greenberg, B., Lowery, D. E., Sharma, S., Schmidt, M. L., & Trojanowski, J. Q. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.6.2249 · Cited by 155
Neurofilament Accumulation Induced in Synapses by Leupeptin
Roots, B. I. (1983) · Science · doi:10.1126/science.6192501 · Cited by 154
Neuropil Threads Occur in Dendrites of Tangle—Bearing Nerve Cells
Braak, H., & Braak, E. (1988) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1988.tb00864.x · Cited by 153
Identification of 3‐ and 4‐repeat tau isoforms within the PHF in Alzheimer's disease.
Jakes, R., Novák, M., Davison, M., & Wischik, C. M. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07820.x · Cited by 151
Neuropathological observations in a case of autism presenting with self-injury behavior
Hof, P. R., Knabe, R., Bovier, P., & Bouras, C. (1991) · Acta Neuropathologica · doi:10.1007/bf00308819 · Cited by 151
β-Amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells
Li, Y., Bushnell, A. F., Lee, C., Perlmutter, L. S., & Wong, S. K.-F. (1996) · Brain Research · doi:10.1016/s0006-8993(96)00733-0 · Cited by 150
Apoptosis Decision Cascades and Neuronal Degeneration in Alzheimer’s Disease
Cotman, C. W. (1998) · Neurobiology of Aging · doi:10.1016/s0197-4580(98)00042-6 · Cited by 150
Regulation of peripherin and neurofilament expression in regenerating rat motor neurons
Troy, C. M., Muma, N. A., Greene, L. A., Price, D. L., & Shelanski, M. L. (1990) · Brain Research · doi:10.1016/0006-8993(90)90832-v · Cited by 150
Delaère, P., He, Y., Fayet, G., Duyckaerts, C., & Hauw, J.-J. (1993) · Neurobiology of Aging · doi:10.1016/0197-4580(93)90096-t · Cited by 149
Neurons express proteins of the classical complement pathway in Alzheimer disease.
Terai, K., Walker, D., Mcgeer, E., & McGeer, P. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00849-4 · Cited by 149
Goldstein, M., Cooper, H., BRUCE, J. S., Carden, M. J., Lee, V., & Schlaepfer, W. W. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-05-01586.1987 · Cited by 145
Neurochemical Diversity of Dystrophic Neurites in the Early and Late Stages of Alzheimer's Disease
Dickson, T. C., King, C., McCormack, G. H., & Vickers, J. C. (1999) · Experimental Neurology · doi:10.1006/exnr.1998.7010 · Cited by 144
Self-citationLucassen, P., Chung, W., Kamphorst, W., & Swaab, D. (1997) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199708000-00007 · Cited by 142
Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus
MacGibbon, G. A., Lawlor, P. A., Sirimanne, E. S., Walton, M. R., Connor, B. J., Young, D., Williams, C. E., Gluckman, P. D., Faull, R. L. M., Hughes, P. E., et al. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01351-0 · Cited by 140
Oblinger, M., & Lasek, R. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-05-01747.1988 · Cited by 135
Antibodies to heavy neurofilament subunit detect a subpopulation of damaged ganglion cells in retina
Dräger, U. C., & Hofbauer, A. (1984) · Nature · doi:10.1038/309624a0 · Cited by 134
Yamasaki, H., Itakura, C., & Mizutani, M. (1991) · Acta Neuropathologica · doi:10.1007/bf00293376 · Cited by 134
Vickers, J. C., Riederer, B. M., Marugg, R. A., Buée‐Scherrer, V., Buée, L., Delacourte, A., & Morrison, J. H. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90310-7 · Cited by 133
Self-citationAlzheimer's paired helical filaments share epitopes with neurofilament side arms.
Miller, C. C. J., Brion, J., Calvert, R. A., Chin, T., Eagles, P. A. M., Downes, M. J., Flament-Durand, J., Haugh, M., Kahn, J., & Probst, A. (1986) · The EMBO Journal · doi:10.1002/j.1460-2075.1986.tb04209.x · Cited by 131
Leterrier, J. F., Rusakov, D. A., Nelson, B. D., et al. (1994) · Microscopy Research and Technique · doi:10.1002/jemt.1070270305 · Cited by 131
Ross, D. T., Meaney, D., Sabol, M., Smith, D. H., & Gennarelli, T. (1994) · Experimental Neurology · doi:10.1006/exnr.1994.1067 · Cited by 130
Alzheimer‐associated presenilin‐2 confers increased sensitivity to poptosis in PC12 cells
Deng, G., Pike, C. J., & Cotman, C. W. (1996) · FEBS Letters · doi:10.1016/s0014-5793(96)01142-8 · Cited by 130
Motte, J., & Williams, R. S. (1989) · Acta Neuropathologica · doi:10.1007/bf00687256 · Cited by 126
β‐Amyloid Neurotoxicity In Vitro: Evidence of Oxidative Stress but Not Protection by Antioxidants
Pike, C. J., Ramezan‐Arab, N., & Cotman, C. W. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69041601.x · Cited by 124
Lee, V. M., Otvos, L. P., Schmidt, M. L., & Trojanowski, J. Q. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.19.7384 · Cited by 124
Hof, P. R. (1992) · Archives of Neurology · doi:10.1001/archneur.1992.00530330070019 · Cited by 118
Li, W. P., Chan, W. Y., Lai, H. W. L., & Yew, D. T. (1997) · Journal of Molecular Neuroscience · doi:10.1007/bf02736774 · Cited by 118
Janicki, S. M., & Monteiro, M. J. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.2.485 · Cited by 118
Ishii, T., Kametani, F., HAGA, S., & Sato, M. T. (1989) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1989.tb01216.x · Cited by 117
Axonal cytoskeletal changes after non-disruptive axonal injury
Jafari, S. S., Maxwell, W. L., Neilson, M., & Graham, D. I. (1997) · Journal of Neurocytology · doi:10.1023/a:1018588114648 · Cited by 116
Relating anatomy to function in Alzheimer's disease
Kanne, S., Balota, D. A., Storandt, M., McKeel, D. W., & Morris, J. C. (1998) · Neurology · doi:10.1212/wnl.50.4.979 · Cited by 116
Neurofibrillary tangles, but not Alzheimer‐type pathology, in a young boxer
Geddes, J. F., Vowles, G. H., Robinson, S. F. D., & Sutcliffe, J. C. (1996) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1996.tb00840.x · Cited by 116
The effect of a conditioning lesion on the regeneration of motor axons
McQuarrie, I. G. (1978) · Brain Research · doi:10.1016/0006-8993(78)91116-2 · Cited by 114
Bons, N., Mestre‐Francés, N., & Petter, A. (1992) · Neurobiology of Aging · doi:10.1016/0197-4580(92)90016-q · Cited by 113
CENTRAL CHROMATOLYSIS AND THE AXON REACTION: A REAPPRAISAL
TORVIK, A. (1976) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1976.tb00516.x · Cited by 111
Uchida, Y., Ihara, Y., & Tomonaga, M. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(88)90765-6 · Cited by 111
Nerve, organ, and tissue regeneration : research perspectives
Seil, F. J. (1983) · Cited by 110
Regeneration in the adult central nervous system: Experimental repair strategies
Olson, L. (1997) · Nature Medicine · doi:10.1038/nm1297-1329 · Cited by 109
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Metadata
- Authors
- Vickers, J.
- Affiliations
- University of Tasmania (AU)
- Corresponding author
- Vickers, J
- ORCID
- Vickers, J
- Venue
- Progress in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2000-02
- Volume
- 60
- Issue
- 2
- Pages
- 139-165
- ISSN
- 0301-0082 (ISSN-L)
- OpenAlex
- W2111417422
- Cited by
- 254
- References
- 329
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 9 · 2023: 7 · 2022: 7 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 4 · 2017: 7 · 2016: 3 · 2015: 6 · 2014: 12 · 2013: 6 · 2012: 7
- FWCI
- 12.98
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- Locations
- Progress in Neurobiology (publishedVersion)
- PubMed (publishedVersion)
- eCite Digital Repository (University of Tasmania) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- Alzheimer's disease, neurodegeneration, amyloid plaques, neurofibrillary tangles, dystrophic neurites, axonal injury, cytoskeletal alterations, dementia, neuroprotection, preclinical Alzheimer's disease
- MeSH terms
- Alzheimer Disease, Animals, Humans, Nerve Degeneration
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