The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Comorbidity of substance use disorders with mood and anxiety disorders
Open accessAbstract
This article reports the results of a cross-national investigation of patterns of comorbidity between substance use and psychiatric disorders in six studies participating in the International Consortium in Psychiatric Epidemiology. In general, there was a strong association between mood and anxiety disorders as well as conduct and antisocial personality disorder with substance disorders at all sites. The results also suggest that there is a continuum in the magnitude of comorbidity as a function of the spectrum of substance use category (use, problems, dependence), as well as a direct relationship between the number of comorbid disorders and increasing levels of severity of substance use disorders (which was particularly pronounced for drugs). Finally, whereas there was no specific temporal pattern of onset for mood disorders in relation to substance disorders, the onset of anxiety disorders was more likely to precede that of substance disorders in all countries. These results illustrate the contribution of cross-national data to understanding the patterns and risk factors for psychopathology and substance use disorders.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370
Self-citationCross-national epidemiology of major depression and bipolar disorder
Weissman, M. M. (1996) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1996.03540040037030 · Cited by 2,302
Kessler, R. C. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830160031005 · Cited by 2,085
Self-citationBijl, R. V., Ravelli, A., & van Zessen, G. (1998) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050098 · Cited by 1,216
Self-citationPrevalence of mental disorders and psychosocial impairments in adolescents and young adults
WITTCHEN, H.-U., NELSON, C. B., & LACHNER, G. (1998) · Psychological Medicine · doi:10.1017/s0033291797005928 · Cited by 821
Familial Transmission of Substance Use Disorders
Merikangas, K. R., Stolar, M., Stevens, D. E., Goulet, J., Preisig, M. A., Fenton, B., Zhang, H., O'Malley, S. S., & Rounsaville, B. J. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.11.973 · Cited by 783
Self-citationComorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey
Grant, B. F., & Harford, T. C. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01160-4 · Cited by 637
The comorbidity of depression and substance use disorders
Swendsen, J. (2000) · Clinical Psychology Review · doi:10.1016/s0272-7358(99)00026-4 · Cited by 632
Self-citationMerikangas, K. R., Angst, J., Eaton, W., Canino, G., Rubio-Stipec, M., Wacker, H., Wittchen, H.-U., Andrade, L., Essau, C., Whitaker, A., et al. (1996) · British Journal of Psychiatry · doi:10.1192/s0007125000298425 · Cited by 293 · cited 3×
“The majority of the existing literature, however, underscores the heterogeneity of these relationships as well as the possibility that causal influences (in both directions) may exist simultaneously with shared diatheses (see Kessler et al., 1997; Merikangas & Gelernter, 1990; Merikangas et al., 1996; Swendsen & Merik…”
BackgroundResultSelf-citationVázquez, C., Muñoz, M., & Sanz, J. (1997) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1997.tb10141.x · Cited by 64
Cited by
Beesdo, K., Knappe, S., & Pine, D. S. (2009) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2009.06.002 · Cited by 1,703
Comorbidity: a network perspective
Cramer, A. O. J., Waldorp, L. J., van der Maas, H. L. J., & Borsboom, D. (2010) · Behavioral and Brain Sciences · doi:10.1017/s0140525x09991567 · Cited by 1,575
Size and burden of mental disorders in Europe—a critical review and appraisal of 27 studies
Wittchen, H.-U., & Jacobi, F. (2005) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2005.04.012 · Cited by 1,503
“(4) Quantitatively and in accordance with most other recent international comparison studies (i.e. Andrade et al., 2000; Merikangas et al., 1998; Weissman et al., 1996, 1997; Wittchen, 1994), anxiety disorders rank as the most frequent (12-month prevalence median: 12%; 36.”
ResultInfluentialAddiction and the brain antireward system
Koob, G. F., & Le Moal, M. (2008) · Annual Review of Psychology · doi:10.1146/annurev.psych.59.103006.093548 · Cited by 1,457
The genetics of addictions: uncovering the genes
Goldman, D., Oroszi, G., & Ducci, F. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1635 · Cited by 1,099
Lorains, F. K., Cowlishaw, S., & Thomas, S. A. (2011) · Addiction · doi:10.1111/j.1360-0443.2010.03300.x · Cited by 1,006
Rehm, J., Room, R., Graham, K., Monteiro, M., Gmel, G., & Sempos, C. T. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00467.x · Cited by 995
Lai, H. M. X., Cleary, M., Sitharthan, T., & Hunt, G. E. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.05.031 · Cited by 941
Conway, K. P., Compton, W., Stinson, F. S., & Grant, B. F. (2006) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v67n0211 · Cited by 934
Lee, S. S., Humphreys, K. L., Flory, K., Liu, R., & Glass, K. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.01.006 · Cited by 875
Boffetta, P., & Hashibe, M. (2006) · The Lancet Oncology · doi:10.1016/s1470-2045(06)70577-0 · Cited by 877
Johnson, E. O., Roth, T., & Breslau, N. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.07.008 · Cited by 804
Toward a syndrome model of addiction: Multiple expressions, common etiology
Shaffer, H. J., LaPlante, D. A., LaBrie, R. A., Kidman, R. C., Donato, A. N., & Stanton, M. V. (2004) · Harvard Review of Psychiatry · doi:10.1080/10673220490905705 · Cited by 682
Jacobson, N. C., & Newman, M. G. (2017) · Psychological Bulletin · doi:10.1037/bul0000111 · Cited by 576
The epidemiology of dual diagnosis
Kessler, R. C. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.06.034 · Cited by 588
Self-citationBeesdo, K., Pine, D. S., Lieb, R., & Wittchen, H.-U. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.177 · Cited by 494
Chan, Y.-F., Dennis, M. L., & Funk, R. R. (2008) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2006.12.031 · Cited by 443
OECD (2021) · OECD Health Policy Studies · doi:10.1787/4ed890f6-en · Cited by 407
ZIMMERMANN, P., WITTCHEN, H.-U., HÖFLER, M., PFISTER, H., KESSLER, R. C., & LIEB, R. (2003) · Psychological Medicine · doi:10.1017/s0033291703008158 · Cited by 366
Self-citationComorbidity between major depression and alcohol use disorder from adolescence to adulthood
Brière, F. N., Rohde, P., Seeley, J. R., Klein, D., & Lewinsohn, P. M. (2014) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.10.007 · Cited by 328
“Evidence on temporal ordering from retrospective studies has been mixed, with studies reporting MDD to most often precede AUD [1,7,8], AUD to most often predece MDD [9] or no clear ordering [2,10].”
Developmental epidemiology of anxiety disorders
Beesdo-Baum, K., & Knappe, S. (2012) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2012.05.001 · Cited by 330
Najt, P., Fusar-Poli, P., & Brambilla, P. (2011) · Psychiatry Research · doi:10.1016/j.psychres.2010.07.042 · Cited by 284
Glantz, M. D., Bharat, C., Degenhardt, L., Sampson, N. A., Scott, K. M., Lim, C. C. W., Al-Hamzawi, A., Alonso, J., Andrade, L. H., Cardoso, G., et al. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2019.106128 · Cited by 272
Self-citationErsche, K. D., Turton, A. J., Chamberlain, S. R., Müller, U., Bullmore, E. T., & Robbins, T. W. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11091421 · Cited by 252
The ESEMeD/MHEDEA 2000 investigators, Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H., de Girolamo, G., de Graaf, R., Demyttenaere, K., et al. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0047.2004.00328.x · Cited by 242
Self-citationRobinson, J. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.75 · Cited by 208
Pathological circuit function underlying addiction and anxiety disorders
Lüthi, A., & Lüscher, C. (2014) · Nature Neuroscience · doi:10.1038/nn.3849 · Cited by 192
Genetic factors influencing alcohol dependence
Mayfield, R. D., Harris, R. A., & Schuckit, M. A. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.88 · Cited by 186
Prevalence of Co-Occurring Substance Use and other Mental Disorders in the Canadian Population
Rush, B., Urbanoski, K., Bassani, D., Castel, S., Wild, T. C., Strike, C., Kimberley, D., & Somers, J. (2008) · The Canadian Journal of Psychiatry · doi:10.1177/070674370805301206 · Cited by 168
Onaemo, V. N., Fawehinmi, T. O., & D'Arcy, C. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.12.043 · Cited by 152
Probability and predictors of treatment-seeking for substance use disorders in the U.S
Blanco, C., Iza, M., Rodríguez-Fernández, J. M., Baca-García, E., Wang, S., & Olfson, M. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.01.031 · Cited by 146
Magnitude and impact of comorbidity of mental disorders from epidemiologic surveys
Merikangas, K. R., & Kalaydjian, A. (2007) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3281c61dc5 · Cited by 122
Self-citationKemp, A. H., Koenig, J., & Thayer, J. F. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.09.006 · Cited by 114
(2010) · doi:10.1037/12067-000 · Cited by 112
Urbanoski, K. A., Cairney, J., Bassani, D. G., & Rush, B. R. (2008) · Psychiatric Services · doi:10.1176/ps.2008.59.3.283 · Cited by 111
Knappe, S., Beesdo-Baum, K., Fehm, L., Stein, M. B., Lieb, R., & Wittchen, H.-U. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.05.002 · Cited by 113
Delgadillo, J., Payne, S., Gilbody, S., Godfrey, C., Gore, S., Jessop, D., & Dale, V. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.03.011 · Cited by 106
Sloboda, Z., Glantz, M. D., & Tarter, R. E. (2012) · Substance Use & Misuse · doi:10.3109/10826084.2012.663280 · Cited by 94
Fatseas, M., Serre, F., Swendsen, J., & Auriacombe, M. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.03.008 · Cited by 89
History of abuse and drinking outcomes following inpatient alcohol treatment: a prospective study
Greenfield, S. F., Kolodziej, M. E., Sugarman, D. E., Muenz, L. R., Vagge, L. M., He, D. Y., & Weiss, R. D. (2002) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00072-8 · Cited by 87
Controversy clarified: an updated review of clinical psychology and tele-health
Perle, J. G., Langsam, L. C., & Nierenberg, B. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.08.003 · Cited by 83
Repetitive transcranial magnetic stimulation and drug addiction
Barr, M. S., Farzan, F., Wing, V. C., George, T. P., Fitzgerald, P. B., & Daskalakis, Z. J. (2011) · International Review of Psychiatry · doi:10.3109/09540261.2011.618827 · Cited by 78
Pilot study of treatment for major depression among women prisoners with substance use disorder
Johnson, J. E., & Zlotnick, C. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.05.007 · Cited by 70
“, 2004; Hasin and Grant, 2002), especially among women (Grant, 1995; Merikangas et al., 1998; Wang and Patten, 2001, 2002).”
BackgroundBerlowitz, I., Walt, H., Ghasarian, C., Mendive, F., & Martin-Soelch, C. (2019) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2019.1607956 · Cited by 72
Otto, M. W., Powers, M. B., & Fischmann, D. (2005) · Clinical Psychology Review · doi:10.1016/j.cpr.2005.05.002 · Cited by 67
The anxious amygdala: CREB signaling and predisposition to anxiety and alcoholism
Wand, G. (2005) · Journal of Clinical Investigation · doi:10.1172/jci26436 · Cited by 66
Past depression and gender interact to influence emotional reactivity to daily life stress
Husky, M. M., Mazure, C. M., Maciejewski, P. K., & Swendsen, J. D. (2009) · Cognitive Therapy and Research · doi:10.1007/s10608-008-9212-z · Cited by 62
Self-citationDevelopmental Pathways to Substance Abuse
Mayes, L. C., & Suchman, N. E. (2015) · Developmental Psychopathology · doi:10.1002/9780470939406.ch16 · Cited by 54
Ummels, S. A., Seldenrijk, A., Bos, E. H., de Graaf, R., Batelaan, N. M., & ten Have, M. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.06.091 · Cited by 50
Ahmadi, J., Jahromi, M. S., & Ehsaei, Z. (2018) · Trials · doi:10.1186/s13063-018-2843-9 · Cited by 48
Wüsthoff, L. E., Waal, H., & Gråwe, R. W. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-67 · Cited by 46
BAILLIE, A. J., STAPINSKI, L., CROME, E., MORLEY, K., SANNIBALE, C., HABER, P., & TEESSON, M. (2010) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2010.00206.x · Cited by 33
Affective Intensity and Lability: Heritability in Adult Male Twins
Coccaro, E. F., Ong, A. D., Seroczynski, A. D., & Bergeman, C. S. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.06.042 · Cited by 29
Adult versus adolescent onset of smoking: How are mood disorders and other risk factors involved?
Ajdacic‐Gross, V., Landolt, K., Angst, J., Gamma, A., Merikangas, K. R., Gutzwiller, F., & Rössler, W. (2009) · Addiction · doi:10.1111/j.1360-0443.2009.02640.x · Cited by 25
Self-citationKhoddam, R., Jackson, N. J., & Leventhal, A. M. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.10.007 · Cited by 24
Predictors of benzodiazepine discontinuation in subjects manifesting complicated dependence
VORMA, H., NAUKKARINEN, H. H., SARNA, S. J., & KUOPPASALMI, K. I. (2005) · Substance Use & Misuse · doi:10.1081/ja-200052433 · Cited by 22
Metadata
- Authors
- Merikangas, K. R., Mehta, R. L., Molnar, B. E., Walters, E. E., Swendsen, J. D., Aguilar-Gaziola, S., Bijl, R., Borges, G., Caraveo-Anduaga, J. J., Dewit, D. J., Kolody, B., Vega, W. A., Wittchen, H.-U., & Kessler, R. C.
- Venue
- Addictive Behaviors
- Publisher
- Elsevier BV
- Published
- 1998-11
- Volume
- 23
- Issue
- 6
- Pages
- 893-907
- ISSN
- 0306-4603 (ISSN-L)
- OpenAlex
- W1597133836
- Cited by
- 725
- References
- 10
- FWCI
- 10.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.