Cited by 836Traumatic Brain Injury ResearchMartial Arts: Techniques, Psychology, and EducationDementia and Cognitive Impairment Research

The aftermath of boxing

Corsellis, J. A. N., Bruton, C. J., Freeman-Browne, Dorothy·1973·Psychological Medicine

Abstract

SYNOPSIS The brains of 15 retired boxers have been studied and the lives of the men concerned have been investigated in retrospect. A characteristic pattern of cerebral change has been identified which appears not only to be a result of the boxing but also to underlie many features of the punch-drunk syndrome.

Integrity signals

Registry

Crossref · 10.1017/s0033291700049588

Cites

43 of 43 references verified0 citation errors · 0 not checkable

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  • Historical cases of dementia pugilistica have pathological descriptions in some cases that appear indistinguishable from PART, consistent with Jordan's hypothesis that dementia pugilistica may in some cases represent the aging process superimposed on fixed structural pathology.

    “Historical cases of dementia pugilistica are interesting in this regard, in that the pathological descriptions in some cases appear indistinguishable from PART [6], consistent with Jordan’s hypothesis that dementia pugilistica may in some cases represent the aging process superimposed on fixed structural pathology [17].”
  • Dementia pugilistica shows considerable intraneuronal Aβ42.

    “In addition, dementia pugilistica that develops in professional boxers [31], while characterized by significant tauopathy and comparably less amyloid pathology, limited mainly to diffuse plaques [27], also shows considerable intraneuronal Aβ42 (Fig. 4c).”
  • Senile plaques are found in 27% of CTE cases.

    “Senile plaques were found in 27 % of cases.”

    From The neuropathology of sport (2014) · cites this paper as [38]

  • The clinical symptoms associated with CTE were examined in case summaries throughout the twentieth century; however, the disease presentation described in these reports was inconsistent.

    “The clinical symptoms associated with this disease were examined in case summaries throughout the twentieth century; however, the disease presentation described in these reports was inconsistent [38, 65, 92, 100, 126].”

    From The neuropathology of sport (2014) · cites this paper as [38]

  • In CTE, neuronal loss occurs in the cerebellar tonsils and substantia nigra, and neurofibrillary degeneration occurs in the substantia nigra and cerebral cortex.

    “Neuronal loss was noted in the cerebellar tonsils and substantia nigra with Cresyl violet stain, and there was neurofibrillary degeneration of the substantia nigra and cerebral cortex using Von Braunmühl’s silver stain.”

    From The neuropathology of sport (2014) · cites this paper as [38]

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Authors
Corsellis, J. A. N., Bruton, C. J., & Freeman-Browne, D.
Venue
Psychological Medicine
Published
1973-08
Volume
3
Issue
3
Pages
270-303
ISSN
  • 0033-2917 (ISSN-L)
  • 1469-8978
OpenAlex
W1894924936
Cited by
836
References
43
Citations by year
2026: 9 · 2025: 21 · 2024: 13 · 2023: 25 · 2022: 26 · 2021: 26 · 2020: 48 · 2019: 54 · 2018: 32 · 2017: 44 · 2016: 43 · 2015: 54 · 2014: 49 · 2013: 39 · 2012: 20
FWCI
7.68
Type
journal article
Language
en
Open access
closed
Locations
  • Psychological Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
  • Social Sciences › Safety Research › Martial Arts: Techniques, Psychology, and Education
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
boxing, brain changes, brain damage, boxing injuries
MeSH terms
Adult, Aged, Boxing, Brain, Brain Damage, Chronic, Brain Stem, Cerebellum, Cerebral Cortex, Dementia, Demyelinating Diseases, Hippocampus, Humans, Male, Middle Aged, Movement Disorders, Nerve Degeneration, Septum Pellucidum, Substantia Nigra

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