Ten good reasons to consider biological processes in prevention and intervention research

Beauchaine, Theodore P.; Neuhaus, Emily; Brenner, Sharon L.; Gatzke-Kopp, Lisa

doi:10.1017/s0954579408000369

Cited by 215Child and Adolescent Psychosocial and Emotional DevelopmentMental Health Research TopicsNeural and Behavioral Psychology Studies

Ten good reasons to consider biological processes in prevention and intervention research

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Beauchaine, Theodore P., Neuhaus, Emily, Brenner, Sharon L., Gatzke-Kopp, Lisa·2008·Development and Psychopathology

DOI 10.1017/s0954579408000369PMC PMC2690981

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Abstract

Most contemporary accounts of psychopathology acknowledge the importance of both biological and environmental influences on behavior. In developmental psychopathology, multiple etiological mechanisms for psychiatric disturbance are well recognized, including those operating at genetic, neurobiological, and environmental levels of analysis. However, neuroscientific principles are rarely considered in current approaches to prevention or intervention. In this article, we explain why a deeper understanding of the genetic and neural substrates of behavior is essential for the next generation of preventive interventions, and we outline 10 specific reasons why considering biological processes can improve treatment efficacy. Among these, we discuss (a) the role of biomarkers and endophenotypes in identifying those most in need of prevention; (b) implications for treatment of genetic and neural mechanisms of homotypic comorbidity, heterotypic comorbidity, and heterotypic continuity; (c) ways in which biological vulnerabilities moderate the effects of environmental experience; (d) situations in which Biology x Environment interactions account for more variance in key outcomes than main effects; and (e) sensitivity of neural systems, via epigenesis, programming, and neural plasticity, to environmental moderation across the life span. For each of the 10 reasons outlined we present an example from current literature and discuss critical implications for prevention.

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Interactions between biology and environment sometimes explain more variance in outcomes than do main effects.
“As interactions between biology and environment sometimes explain more variance in outcomes than do main effects (Beauchaine et al., 2008), accounting for these neural factors can clarify why some adolescents may be more primed for good or bad outcomes given their combination of neural susceptibility and social-contextual exposures.”
From Adolescent neurobiological susceptibility to social context (2016) · cites this paper as Beauchaine et al., 2008

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,588 · see citing works
The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.
Baron, R. M., & Kenny, D. A. (1986) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.51.6.1173 · Cited by 91,542 · see citing works
The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations
Baron, R. M., & Kenny, D. A. (1986) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.51.6.1173 · Cited by 91,532 · see citing works
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,406 · see citing works
Multiple regression: testing and interpreting interactions
(1992) · Choice Reviews Online · doi:10.5860/choice.29-3352 · Cited by 36,644 · see citing works
<i>The Structure of Scientific Revolutions</i>
Kuhn, T. S., & Schlegel, R. (1963) · Physics Today · doi:10.1063/1.3050879 · Cited by 35,538 · see citing works
Cognitive Therapy for Depression
(2012) · PsycEXTRA Dataset · doi:10.1037/e675542012-001 · Cited by 9,678 · see citing works
The Construct of Resilience: A Critical Evaluation and Guidelines for Future Work
Luthar, S. S., Cicchetti, D., & Becker, B. (2000) · Child Development · doi:10.1111/1467-8624.00164 · Cited by 9,381 · see citing works
THE STRUCTURE OF SCIENTIFIC REVOLUTIONS
McGuire, J. E. (1963) · Philosophical Books · doi:10.1111/j.1468-0149.1963.tb00813.x · Cited by 8,544 · see citing works
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120 · see citing works
Untitled work
(1993) · Cited by 7,136 · see citing works
Neurogenesis in the adult human hippocampus
Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369 · see citing works
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177 · see citing works
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
Gottesman, I. I., & Gould, T. D. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.4.636 · Cited by 5,615 · see citing works
Role of genotype in the cycle of violence in maltreated children
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., Taylor, A., & Poulton, R. (2002) · Science · doi:10.1126/science.1072290 · Cited by 4,842 · see citing works
Cognitive Therapy of Depression
HOLLON, S. D., & BECK, A. T. (1979) · Cognitive-Behavioral Interventions · doi:10.1016/b978-0-12-404480-7.50012-5 · Cited by 4,685 · see citing works
Précis of <i>The neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system</i>
Gray, J. A. (1982) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00013066 · Cited by 4,477 · see citing works
The Behavior of Organisms: An Experimental Analysis
Jones, F. N., & Skinner, B. F. (1939) · The American Journal of Psychology · doi:10.2307/1416495 · Cited by 4,388 · see citing works
Principles of Behavior
Skinner, B. F., & Hull, C. L. (1944) · The American Journal of Psychology · doi:10.2307/1416955 · Cited by 4,061 · see citing works
Epigenetic differences arise during the lifetime of monozygotic twins
Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Heine-Suñer, D., Cigudosa, J. C., Urioste, M., Benitez, J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500398102 · Cited by 3,602 · see citing works
On the practice of dichotomization of quantitative variables.
MacCallum, R. C., Zhang, S., Preacher, K. J., & Rucker, D. D. (2002) · Psychological Methods · doi:10.1037/1082-989x.7.1.19 · Cited by 3,538 · see citing works
Genetic Epidemiology of Major Depression: Review and Meta-Analysis
Sullivan, P. F., Neale, M. C., & Kendler, K. S. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.10.1552 · Cited by 3,431 · see citing works
A 14-Month Randomized Clinical Trial of Treatment Strategies for Attention-Deficit/Hyperactivity Disorder
(1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.12.1073 · Cited by 3,372 · see citing works
A developmental perspective on antisocial behavior.
Patterson, G. R., DeBaryshe, B. D., & Ramsey, E. A. (1989) · American Psychologist · doi:10.1037//0003-066x.44.2.329 · Cited by 2,950 · see citing works
Mediators and Moderators of Treatment Effects in Randomized Clinical Trials
Kraemer, H. C., Wilson, G. T., Fairburn, C. G., & Agras, W. S. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.10.877 · Cited by 2,562 · cited 2× · see citing works
“Accordingly, prevention and intervention researchers who consider biologically based individual differences as moderators of treatment outcome should calculate the statistical power of interaction effects in advance to ensure that any null findings are not the result of inadequate sample size (Kraemer et al., 2002; Wh…”
Background
Mapping cortical change across the human life span
Sowell, E. R., Peterson, B. S., Thompson, P. M., Welcome, S. E., Henkenius, A. L., & Toga, A. W. (2003) · Nature Neuroscience · doi:10.1038/nn1008 · Cited by 2,328 · see citing works
The mesolimbic dopamine reward circuit in depression
Nestler, E. J., & Carlezon, W. A. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.09.018 · Cited by 2,059 · see citing works
A developmental perspective on antisocial behavior
Patterson, G. R., DeBaryshe, B. D., & Ramsey, E. (1989) · American Psychologist · doi:10.1037/0003-066x.44.2.329 · Cited by 2,048 · see citing works
Schizotaxia, schizotypy, schizophrenia.
Meehl, P. E. (1962) · American Psychologist · doi:10.1037/h0041029 · Cited by 2,036 · see citing works
When interventions harm: Peer groups and problem behavior.
Dishion, T. J., McCord, J., & Poulin, F. (1999) · American Psychologist · doi:10.1037/0003-066x.54.9.755 · Cited by 2,023 · see citing works
Matching Alcoholism Treatments to Client Heterogeneity: Project MATCH posttreatment drinking outcomes.
(1997) · Journal of Studies on Alcohol · doi:10.15288/jsa.1997.58.7 · Cited by 1,905 · see citing works
Comorbidity
Angold, A., Costello, E. J., & Erkanli, A. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00424 · Cited by 1,872 · see citing works
Parsing reward
Berridge, K. C., & Robinson, T. E. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00233-9 · Cited by 1,869 · see citing works
The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women
Kendler, K. S., Prescott, C. A., Myers, J., & Neale, M. C. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.9.929 · Cited by 1,868 · see citing works
Equifinality and multifinality in developmental psychopathology
Cicchetti, D., & Rogosch, F. A. (1996) · Development and Psychopathology · doi:10.1017/s0954579400007318 · Cited by 1,842 · cited 2× · see citing works
“The same set of vulnerabilities may be associated with various outcomes depending on a multitude of intervening risk factors (multifinality), and individuals can arrive at the same outcome via different combinations of vulnerability and risk (equifinality; Cicchetti & Rogosch, 1996).”
Background
How Do Risk Factors Work Together? Mediators, Moderators, and Independent, Overlapping, and Proxy Risk Factors
Kraemer, H. C., Stice, E., Kazdin, A., Offord, D., & Kupfer, D. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.6.848 · Cited by 1,712 · see citing works
Childhood predictors differentiate life-course persistent and adolescence-limited antisocial pathways among males and females
MOFFITT, T. E., & CASPI, A. (2001) · Development and Psychopathology · doi:10.1017/s0954579401002097 · Cited by 1,669 · cited 2× · see citing works
“Equifinality is also observed in the development of CD. Adolescents who meet criteria form a heterogeneous group, often varying in both developmental history and symptom presentation (Hinshaw & Lee, 2003; Moffitt & Caspi, 2001).”
Background
The Domain of Developmental Psychopathology
Sroufe, L. A., & Rutter, M. L. (1984) · Child Development · doi:10.2307/1129832 · Cited by 1,485 · see citing works
Vagal tone, development, and Gray’s motivational theory: toward an integrated model of autonomic nervous system functioning in psychopathology
BEAUCHAINE, T. (2001) · Development and Psychopathology · doi:10.1017/s0954579401002012 · Cited by 1,466 · see citing works
Self-citation
Etiologic connections among substance dependence, antisocial behavior and personality: Modeling the externalizing spectrum.
Krueger, R. F., Hicks, B. M., Patrick, C. J., Carlson, S. R., Iacono, W. G., & McGue, M. (2002) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.111.3.411 · Cited by 1,378 · see citing works
Key issues in the development of aggression and violence from childhood to early adulthood.
Loeber, R., & Hay, D. (1997) · Annual Review of Psychology · doi:10.1146/annurev.psych.48.1.371 · Cited by 1,339 · see citing works
Risk and Protective Factors in the Development of Psychopathology
(1990) · Cambridge University Press eBooks · doi:10.1017/cbo9780511752872 · Cited by 1,305 · see citing works
Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder
Baxter, L. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090009002 · Cited by 1,293 · see citing works
A developmental psychopathology perspective on adolescence.
Cicchetti, D., & Rogosch, F. A. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.70.1.6 · Cited by 1,243 · see citing works
Reinterpreting comorbidity: a model-based approach to understanding and classifying psychopathology
Krueger, R. F., & Markon, K. E. (2006) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.2.022305.095213 · Cited by 1,171 · see citing works
Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder
Dawson, G. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000370 · Cited by 1,138 · see citing works
Depression: Perspectives from Affective Neuroscience
Davidson, R. J., Pizzagalli, D., Nitschke, J. B., & Putnam, K. (2002) · Annual Review of Psychology · doi:10.1146/annurev.psych.53.100901.135148 · Cited by 1,138 · see citing works
Early externalizing behavior problems: Toddlers and preschoolers at risk for later maladjustment
CAMPBELL, S. B., SHAW, D. S., & GILLIOM, M. (2000) · Development and Psychopathology · doi:10.1017/s0954579400003114 · Cited by 1,081 · see citing works
Modulation of Cortical-Limbic Pathways in Major Depression: Treatment-Specific Effects of Cognitive Behavior Therapy
Goldapple, K., Segal, Z., Garson, C., Lau, M., Bieling, P., Kennedy, S., & Mayberg, H. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.1.34 · Cited by 1,068 · see citing works
Randomized Controlled Trial of Interventions Designed to Reduce the Risk of Progression to First-Episode Psychosis in a Clinical Sample With Subthreshold Symptoms
McGorry, P. D., Yung, A. R., Phillips, L. J., Yuen, H. P., Francey, S., Cosgrave, E. M., Germano, D., Bravin, J., McDonald, T., Blair, A., et al. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.10.921 · Cited by 1,056 · see citing works
a dynamic developmental theory of attention-deficit/hyperactivity disorder (adhd) predominantly hyperactive/impulsive and combined subtypes
sagvolden, T., johansen, E. B., aase, H., & russell, V. A. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000075 · Cited by 1,035 · see citing works
The neurodevelopmental model of schizophrenia: update 2005
Rapoport, J. L., Addington, A. M., Frangou, S., & Psych, M. R. C. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001642 · Cited by 993 · see citing works
ADHD Comorbidity Findings From the MTA Study: Comparing Comorbid Subgroups
JENSEN, P. S., HINSHAW, S. P., KRAEMER, H. C., LENORA, N., NEWCORN, J. H., ABIKOFF, H. B., MARCH, J. S., ARNOLD, L. E., CANTWELL, D. P., CONNERS, C. K., et al. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200102000-00009 · Cited by 974 · see citing works
Psychological Treatments That Cause Harm
Lilienfeld, S. O. (2007) · Perspectives on Psychological Science · doi:10.1111/j.1745-6916.2007.00029.x · Cited by 959 · see citing works
Developmental psychopathology: Concepts and challenges
Rutter, M. L., & Sroufe, L. A. (2000) · Development and Psychopathology · doi:10.1017/s0954579400003023 · Cited by 946 · see citing works
Reinforcement sensitivity theory and personality
Corr, P. J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.01.005 · Cited by 902 · see citing works
Selective effects of methylphenidate in attention deficit hyperactivity disorder: a functional magnetic resonance study
Vaidya, C. J., Austin, G., Kirkorian, G., Ridlehuber, H. W., Desmond, J. E., Glover, G. H., & Gabrieli, J. D. E. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.24.14494 · Cited by 845 · see citing works
Early identification of chronic offenders: Who is the fledgling psychopath?
Lynam, D. R. (1996) · Psychological Bulletin · doi:10.1037/0033-2909.120.2.209 · Cited by 804 · see citing works
Child Psychopathology
Melmed, R. D. (1997) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-199710000-00014 · Cited by 772 · see citing works
Comorbidity of anxiety and depression in children and adolescents
Brady, E. U., & Kendall, P. C. (1992) · Psychological Bulletin · doi:10.1037/0033-2909.111.2.244 · Cited by 748 · see citing works
On the distinction between attentional deficits/hyperactivity and conduct problems/aggression in child psychopathology.
Hinshaw, S. P. (1987) · Psychological Bulletin · doi:10.1037/0033-2909.101.3.443 · Cited by 738 · see citing works
Brief intervention for harm reduction with alcohol-positive older adolescents in a hospital emergency department.
Monti, P. M., Colby, S. M., Barnett, N. P., Spirito, A., Rohsenow, D. J., Myers, M., Woolard, R., & Lewander, W. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.6.989 · Cited by 736 · see citing works
Brief intervention for harm reduction with alcohol-positive older adolescents in a hospital emergency department.
Monti, P. M., Colby, S. M., Barnett, N. P., Spirito, A., Rohsenow, D. J., Myers, M. G., Woolard, R. H., & Lewander, W. J. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.6.989 · Cited by 724 · see citing works
Comorbidity.
Angold, A. C., Costello, E. J., & Erkanli, A. (1999) · PubMed · Cited by 723 · see citing works
Polyvagal Theory and developmental psychopathology: Emotion dysregulation and conduct problems from preschool to adolescence
Beauchaine, T. P., Gatzke-Kopp, L., & Mead, H. K. (2007) · Biological Psychology · doi:10.1016/j.biopsycho.2005.08.008 · Cited by 722 · see citing works
Self-citation
Conditioned Reflexes and Neuron Organization.
(1949) · Annals of Internal Medicine · doi:10.7326/0003-4819-31-6-1133_1 · Cited by 688 · see citing works
Effective psychosocial treatments of conduct-disordered children and adolescents: 29 years, 82 studies, and 5,272 kids
Brestan, E. V., & Eyberg, S. M. (1998) · Journal of Clinical Child Psychology · doi:10.1207/s15374424jccp2702_5 · Cited by 679 · see citing works
Fetal Nicotine or Cocaine Exposure: Which One is Worse?
Slotkin, T. A. (1998) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37495-6 · Cited by 676 · see citing works
The Neural Correlates of Anhedonia in Major Depressive Disorder
Keedwell, P. A., Andrew, C., Williams, S. C. R., Brammer, M. J., & Phillips, M. L. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.05.019 · Cited by 650 · see citing works
Developmental psychopathology, Vol. 1: Theory and methods.
Cicchetti, D., & Cohen, D. J. (1995) · Cited by 645 · see citing works
Depressive comorbidity in children and adolescents: empirical, theoretical, and methodological issues
(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.12.1779 · Cited by 626 · see citing works
Genetic and Environmental Influences on Trauma Exposure and Posttraumatic Stress Disorder Symptoms: A Twin Study
Stein, M. B., Jang, K. L., Taylor, S. J., Vernon, P. A., & Livesley, W. J. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1675 · Cited by 602 · see citing works
The interaction between impulsivity and neighborhood context on offending: The effects of impulsivity are stronger in poorer neighborhoods.
Lynam, D. R., Caspi, A., Moffit, T. E., Wikström, P.-O., Loeber, R., & Novak, S. (2000) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.109.4.563 · Cited by 593 · see citing works
Findings from the NIMH Multimodal Treatment Study of ADHD (MTA): Implications and Applications for Primary Care Providers
JENSEN, P. S., HINSHAW, S. P., SWANSON, J. M., GREENHILL, L. L., CONNERS, C. K., ARNOLD, L. E., ABIKOFF, H. B., ELLIOTT, G., HECHTMAN, L., HOZA, B., et al. (2001) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200102000-00008 · Cited by 591 · see citing works
Handbook of Psychopathy
Patrick, C. J. (2007) · Cited by 587 · see citing works
Interaction between conduct disorder and its comorbid conditions: Effects of age and gender
Loeber, R. (1994) · Clinical Psychology Review · doi:10.1016/0272-7358(94)90015-9 · Cited by 575 · see citing works
Erratum to: “Parsing reward” [Trends Neurosci. 26 (2003) 507–513]
Berridge, K. C., & Robinson, T. E. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.09.001 · Cited by 559 · see citing works
Neuropsychological impairments in schizophrenia: Integration of performance-based and brain imaging findings.
Reichenberg, A., & Harvey, P. D. (2007) · Psychological Bulletin · doi:10.1037/0033-2909.133.5.833 · Cited by 536 · see citing works
Affective neuroscience and psychophysiology: Toward a synthesis
Davidson, R. J. (2003) · Psychophysiology · doi:10.1111/1469-8986.00067 · Cited by 535 · see citing works
Development of Psychopathology: A Vulnerability-Stress Perspective
Hankin, B. L., & Abela, J. R. Z. (2005) · Sage eBooks · doi:10.4135/9781452231655 · Cited by 522 · see citing works
Cognitive-behavioral treatment of borderline personality disorder
Brasfield, C. R. (1994) · Behaviour Research and Therapy · doi:10.1016/0005-7967(94)90183-x · Cited by 517 · see citing works
Psychiatric endophenotypes and the development of valid animal models
Gould, T. D., & Gottesman, I. I. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2005.00186.x · Cited by 507 · see citing works
Ventral Striatal Hyporesponsiveness During Reward Anticipation in Attention-Deficit/Hyperactivity Disorder
Scheres, A., Milham, M. P., Knutson, B., & Castellanos, F. X. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.042 · Cited by 499 · see citing works
Child and adolescent psychopathology
(2008) · Choice Reviews Online · doi:10.5860/choice.46-1183 · Cited by 498 · see citing works
Use of fMRI to Predict Recovery From Unipolar Depression With Cognitive Behavior Therapy
Siegle, G. J., Carter, C. S., & Thase, M. E. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.4.735 · Cited by 495 · see citing works
Amphetamine-induced increases in extracellular dopamine, drug wanting, and novelty seeking: a PET/[11C] raclopride study in healthy men
Leyton, M. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00366-4 · Cited by 476 · see citing works
Defining the broader phenotype of autism: genetic, brain, and behavioral perspectives
DAWSON, G., WEBB, S., SCHELLENBERG, G. D., DAGER, S., FRIEDMAN, S., AYLWARD, E., & RICHARDS, T. (2002) · Development and Psychopathology · doi:10.1017/s0954579402003103 · Cited by 467 · see citing works
Lack of Ventral Striatal Response to Positive Stimuli in Depressed Versus Normal Subjects
Epstein, J., Pan, H., Kocsis, J. H., Yang, Y., Butler, T., Chusid, J., Hochberg, H., Murrough, J., Strohmayer, E., Stern, E., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.10.1784 · Cited by 464 · see citing works
Mediators, Moderators, and Predictors of 1-Year Outcomes Among Children Treated for Early-Onset Conduct Problems: A Latent Growth Curve Analysis.
Beauchaine, T. P., Webster-Stratton, C., & Reid, M. J. (2005) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.73.3.371 · Cited by 454 · see citing works
Self-citation
“Change the mind and you change the brain”: effects of cognitive-behavioral therapy on the neural correlates of spider phobia
Paquette, V., Lévesque, J., Mensour, B., Leroux, J.-M., Beaudoin, G., Bourgouin, P., & Beauregard, M. (2003) · NeuroImage · doi:10.1016/s1053-8119(02)00030-7 · Cited by 452 · see citing works
Revisiting the role of the prefrontal cortex in the pathophysiology of attention-deficit/hyperactivity disorder.
Halperin, J. M., & Schulz, K. P. (2006) · Psychological Bulletin · doi:10.1037/0033-2909.132.4.560 · Cited by 446 · cited 1× · see citing works
“The mesolimbic DA system, which develops very early in life, is modulated in adolescence and adulthood by the mesocortical DA system (see Halperin & Schulz, 2006; Spear, 2007), a frontal neural network that exhibits experience-dependent development into young adulthood (see above).”
Background
The Treatment of Conduct Problems in Children With Callous-Unemotional Traits.
Hawes, D. J., & Dadds, M. R. (2005) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.73.4.737 · Cited by 441 · see citing works
Longer‐term primary prevention for alcohol misuse in young people: a systematic review
Foxcroft, D. R., Ireland, D., Lister‐Sharp, D. J., Lowe, G., & Breen, R. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00355.x · Cited by 433 · see citing works
Co-occurrence of conduct problems and depressive symptoms in early adolescent boys: II. A 2-year follow-up at Grade 8
Capaldi, D. M. (1992) · Development and Psychopathology · doi:10.1017/s0954579400005605 · Cited by 423 · see citing works
Designing, testing, and interpreting interactions and moderator effects in family research
Whisman, M. A., & McClelland, G. H. (2005) · Journal of Family Psychology · doi:10.1037/0893-3200.19.1.111 · Cited by 421 · cited 3× · see citing works
“…is that statistical interactions,which specify the moderation effect, have considerably less power than the main effects in a regression or analysis of variance (ANOVA) model (Aiken & West, 1991; Beauchaine & Mead, 2006; Kraemer, Wilson, Fairburn, & Agras, 2002; Whisman & McClelland, 2005).”
Background
The interaction between impulsivity and neighborhood context on offending: The effects of impulsivity are stronger in poorer neighborhoods.
Lynam, D. R., Caspi, A., Moffitt, T. E., et al. (2000) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.109.4.563 · Cited by 421 · see citing works
Co-occurrence of conduct problems and depressive symptoms in early adolescent boys: III. Prediction to young-adult adjustment
Capaldi, D. M., & Stoolmiller, M. (1999) · Development and Psychopathology · doi:10.1017/s0954579499001959 · Cited by 419 · see citing works
Cerebral Glucose Metabolism in Childhood-Onset Obsessive-Compulsive Disorder
Swedo, S. E. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090018003 · Cited by 413 · see citing works
Integrating nature and nurture: Implications of person–environment correlations and interactions for developmental psychopathology
Rutter, M. L., Dunn, J., Plomin, R. J., Simonoff, E. A., Pickles, A. R., Maughan, B., Ormel, J., Meyer, J. M., & Eaves, L. J. (1997) · Development and Psychopathology · doi:10.1017/s0954579497002083 · Cited by 402 · see citing works
Exposure to Interparental Conflict and Children's Adjustment and Physical Health: The Moderating Role of Vagal Tone
El-Sheikh, M., Harger, J., & Whitson, S. M. (2001) · Child Development · doi:10.1111/1467-8624.00369 · Cited by 396 · see citing works
Measured Gene-Environment Interactions in Psychopathology: Concepts, Research Strategies, and Implications for Research, Intervention, and Public Understanding of Genetics
Moffitt, T. E., Caspi, A., & Rutter, M. (2006) · Perspectives on Psychological Science · doi:10.1111/j.1745-6916.2006.00002.x · Cited by 389 · see citing works
A review of the biological bases of ADHD: What have we learned from imaging studies?
Durston, S. (2003) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.10079 · Cited by 388 · see citing works
Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights
Kaffman, A., & Meaney, M. J. (2007) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2007.01730.x · Cited by 385 · see citing works
Developmental psychopathology
Turk, J., GRAHAM, P. J., & Verhulst, F. C. (2007) · Oxford University Press eBooks · doi:10.1093/med/9780199216697.003.0004 · Cited by 369 · see citing works
Acute stress reduces reward responsiveness: Implications for depression
Bogdan, R., & Pizzagalli, D. A. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.037 · Cited by 364 · see citing works
Barriers to dissemination of evidence-based practices: Addressing practitioners’ concerns about manual-based psychotherapies
Addis, M. E., Wade, W. A., & Hatgis, C. (1999) · Clinical Psychology: Science and Practice · doi:10.1093/clipsy.6.4.430 · Cited by 362 · see citing works
Differential Heritability of Adult and Juvenile Antisocial Traits
Lyons, M. J. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950230020005 · Cited by 333 · see citing works
Bringing basic research on early experience and stress neurobiology to bear on preventive interventions for neglected and maltreated children
Gunnar, M. R., Fisher, P. A., & THE EARLY EXPERIENCE, S. (2006) · Development and Psychopathology · doi:10.1017/s0954579406060330 · Cited by 329 · see citing works
Nature × nurture: Genetic vulnerabilities interact with physical maltreatment to promote conduct problems
JAFFEE, S. R., CASPI, A., MOFFITT, T. E., DODGE, K. A., RUTTER, M., TAYLOR, A., & TULLY, L. A. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050042 · Cited by 328 · see citing works
Efficacy of Cognitive–Behavioral Interventions Targeting Personality Risk Factors for Youth Alcohol Misuse
Conrod, P., Stewart, S. H., Comeau, N., & MacLean, A. (2006) · Journal of Clinical Child & Adolescent Psychology · doi:10.1207/s15374424jccp3504_6 · Cited by 323 · see citing works
The genetic aetiology of childhood depression: a review
Rice, F. J., Harold, G. T., & Thapar, A. (2002) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00004 · Cited by 313 · see citing works
Cognitive and behavioral precursors of schizophrenia
Cornblatt, B. A., Obuchowski, M., Roberts, S., Pollack, S. Z., & Erlenmeyer‐Kimling, L. (1999) · Development and Psychopathology · doi:10.1017/s0954579499002175 · Cited by 311 · see citing works
Reward‐related decision‐making in pediatric major depressive disorder: an fMRI study
Forbes, E. E., Christopher May, J., Siegle, G. J., Ladouceur, C. D., Ryan, N. D., Carter, C. S., Birmaher, B., Axelson, D. A., & Dahl, R. E. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01673.x · Cited by 299 · see citing works
Schizophrenia: a common disease caused by multiple rare alleles
McClellan, J. M., Susser, E., & King, M.-C. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.025585 · Cited by 296 · see citing works
Disinhibitory psychopathology in male adolescents: discriminating conduct disorder from attention-deficit/hyperactivity disorder through concurrent assessment of multiple autonomic states
Beauchaine, T. P., Katkin, E. S., Strassberg, Z., & Snarr, J. (2001) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.110.4.610 · Cited by 288 · see citing works
Self-citation
Disinhibitory psychopathology in male adolescents: Discriminating conduct disorder from attention-deficit/hyperactivity disorder through concurrent assessment of multiple autonomic states.
Beauchaine, T. P., Katkin, E. S., Strassberg, Z., & Snarr, J. (2001) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.110.4.610 · Cited by 287 · see citing works
Self-citation
Preventive intervention for maltreated preschool children: impact on children's behavior, neuroendocrine activity, and foster parent functioning
FISHER, P. A., GUNNAR, M. R., CHAMBERLAIN, P., & REID, J. B. (2000) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200011000-00009 · Cited by 286 · see citing works
Genetic moderation of environmental risk for depression and anxiety in adolescent girls
Silberg, J., Rutter, M., Neale, M., & Eaves, L. (2001) · British Journal of Psychiatry · doi:10.1192/bjp.179.2.116 · Cited by 285 · see citing works
Gene-environment interdependence.
Rutter, M. (2007) · Developmental Science · doi:10.1111/j.1467-7687.2007.00557.x · Cited by 283 · see citing works
Spatial working memory as an endophenotype for schizophrenia
Glahn, D. C., Therman, S., Manninen, M., HUTTUNEN, M. O., Kaprio, J., Lönnqvist, J. K., & Cannon, T. D. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01641-4 · Cited by 283 · see citing works
Early identification of the fledgling psychopath: Locating the psychopathic child in the current nomenclature.
Lynam, D. R. (1998) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.107.4.566 · Cited by 278 · see citing works
Conduct and Oppositional Defiant Disorders
Ghuman, H. S., & Sarles, R. M. (2013) · Routledge eBooks · doi:10.4324/9780203777893-23 · Cited by 275 · see citing works
Buffering children from marital conflict and dissolution
Katz, L. F., & Gottman, J. M. (1997) · Journal of Clinical Child Psychology · doi:10.1207/s15374424jccp2602_4 · Cited by 274 · see citing works
Changes in Anterior Cingulate and Amygdala After Cognitive Behavior Therapy of Posttraumatic Stress Disorder
Felmingham, K. L., Kemp, A. H., Williams, L. M., Das, P., Hughes, G., Peduto, A. S., & Bryant, R. A. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.01860.x · Cited by 270 · see citing works
Project DARE: No effects at 10-year follow-up.
Lynam, D. R., Milich, R. S., Zimmerman, R. S., Novak, S. P., Logan, T., Martin, C. A., Leukefeld, C. G., & Clayton, R. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.4.590 · Cited by 266 · see citing works
Effects of Environmental Enrichment at Ages 3–5 Years on Schizotypal Personality and Antisocial Behavior at Ages 17 and 23 Years
Raine, A., Mellingen, K., Liu, J., Venables, P. H., & Mednick, S. A. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.9.1627 · Cited by 263 · see citing works
Delinquent behavior and emerging substance use in the MTA at 36 months: prevalence, course, and treatment effects
MOLINA, B. S. G., FLORY, K., HINSHAW, S. P., GREINER, A. R., ARNOLD, L. E., SWANSON, J. M., HECHTMAN, L., JENSEN, P. S., VITIELLO, B., HOZA, B., et al. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e3180686d96 · Cited by 255 · see citing works
Role of personality self-organization in development of mental order and disorder
CLONINGER, C. R., SVRAKIC, N. M., & SVRAKIC, D. M. (1997) · Development and Psychopathology · doi:10.1017/s095457949700148x · Cited by 251 · see citing works
Editorial: Multiple levels of analysis
Cicchetti, D., & Dawson, G. (2002) · Development and Psychopathology · doi:10.1017/s0954579402003012 · Cited by 251 · see citing works
Cognitive)ehavioral intervention with aggressive boys: Three-year follow-up and preventive effects.
Lochman, J. E. (1992) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.60.3.426 · Cited by 250 · see citing works
The prevalence and co-morbidity of subthreshold psychiatric conditions
Lewinsohn, P. M., Shankman, S. A., Gau, J. M., & Klein, D. N. (2004) · Psychological Medicine · doi:10.1017/s0033291703001466 · Cited by 249 · see citing works
Project DARE: No effects at 10-year follow-up.
Lynam, D. R., Milich, R. S., Zimmerman, R. S., Novak, S. P., Logan, T., Martin, C. A., Leukefeld, C. G., & Clayton, R. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.4.590 · Cited by 248 · see citing works
Environmentally Mediated Risks for Psychopathology: Research Strategies and Findings
Rutter, M. L. (2004) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000145374.45992.c9 · Cited by 246 · see citing works
Gender differences and developmental change in externalizing disorders from late adolescence to early adulthood: A longitudinal twin study.
Hicks, B. M., Blonigen, D., Kramer, M., Krueger, R., Patrick, C. J., Iacono, W., & McGue, M. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.3.433 · Cited by 243 · see citing works
Detection of the schizoid taxon with MMPI indicators.
Golden, R. R., & Meehl, P. E. (1979) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.88.3.217 · Cited by 240 · see citing works
Cognitive-behavioral intervention with aggressive boys: Three-year follow-up and preventive effects.
Lochman, J. E. (1992) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.60.3.426 · Cited by 240 · see citing works
Co-occurrence of conduct problems and depressive symptoms in early adolescent boys: I. Familial factors and general adjustment at Grade 6
Capaldi, D. M. (1991) · Development and Psychopathology · doi:10.1017/s0954579400005319 · Cited by 239 · see citing works
A Multiple‐Levels‐of‐Analysis Perspective on Resilience
Cicchetti, D., & Blender, J. A. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1376.029 · Cited by 233 · see citing works
Psychological, autonomic, and serotonergic correlates of parasuicide among adolescent girls
CROWELL, S. E., BEAUCHAINE, T. P., McCAULEY, E., SMITH, C. J., STEVENS, A. L., & SYLVERS, P. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050522 · Cited by 229 · see citing works
Self-citation
Validation of a system of classifying female substance abusers on the basis of personality and motivational risk factors for substance abuse.
Conrod, P., Pihl, R. O., Stewart, S. H., & Dongier, M. (2000) · Psychology of Addictive Behaviors · doi:10.1037//0893-164x.14.3.243 · Cited by 226 · see citing works
Hyperactive and antisocial behaviors: Comorbid or two points in the same process?
Patterson, G. R., DeGarmo, D. S., & Knutson, N. (2000) · Development and Psychopathology · doi:10.1017/s0954579400001061 · Cited by 225 · see citing works
'Scared Straight' and other juvenile awareness programs for preventing juvenile delinquency
Petrosino, A. J., Turpin‐Petrosino, C., Hollis-Peel, M. E., & Lavenberg, J. G. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002796.pub2 · Cited by 220 · see citing works
The Genetics of Smoking Initiation and Quantity Smoked in Dutch Adolescent and Young Adult Twins
Koopmans, J. R., Slutske, W., Heath, A., Neale, M., & Boomsma, D. (1999) · Behavior Genetics · doi:10.1023/a:1021618719735 · Cited by 219 · see citing works
The Interplay of Nature, Nurture, and Developmental Influences
Rutter, M. L. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.11.996 · Cited by 219 · see citing works
Clinical Implications of a Link between Fetal Alcohol Spectrum Disorder and Attention-Deficit Hyperactivity Disorder
O’Malley, K. D., & Nanson, J. (2002) · The Canadian Journal of Psychiatry · doi:10.1177/070674370204700405 · Cited by 211 · see citing works
Age effects in parent training outcome.
Dishion, T., & Patterson, G. (1992) · Behavior Therapy · doi:10.1016/s0005-7894(05)80231-x · Cited by 208 · see citing works
Maternal programming of defensive responses through sustained effects on gene expression
Zhang, T.-Y., Bagot, R., Parent, C., Nesbitt, C., Bredy, T. W., Caldji, C., Fish, E., Anisman, H., Szyf, M., & Meaney, M. J. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.01.009 · Cited by 206 · see citing works
Early identification of the fledgling psychopath: Locating the psychopathic child in the current nomenclature.
Lynam, D. R. (1998) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.107.4.566 · Cited by 204 · see citing works
A 30-Year Prospective Follow-up Study of Hyperactive Boys With Conduct Problems
SATTERFIELD, J. H., FALLER, K. J., CRINELLA, F. M., SCHELL, A. M., SWANSON, J. M., & HOMER, L. D. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318033ff59 · Cited by 200 · cited 2× · see citing works
“…hyperactive boys with conduct problems who undergo pharmacological and/or behavioral treatments early in childhood are not protected from delinquency in later childhood, or from criminality as adults, even when shortterm outcomes are favorable (Molina et al., 2007; Satterfield et al., 2007).”
Background
Co-occurrence of depressive symptoms and antisocial behavior in adolescence: A common genetic liability.
O’Connor, T. G., McGuire, S. A., Reiss, D., Hetherington, E. M., & Plomin, R. J. (1998) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.107.1.27 · Cited by 198 · see citing works
Catechol-o-Methyltransferase Enzyme Activity and Protein Expression in Human Prefrontal Cortex across the Postnatal Lifespan
Tunbridge, E., Weickert, C., Kleinman, J., Herman, M., Chen, J., Kolachana, B., Harrison, P., & Weinberger, D. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhl032 · Cited by 197 · see citing works
Early educational and health enrichment at age 3–5 years is associated with increased autonomic and central nervous system arousal and orienting at age 11 years: evidence from the Mauritius Child Health Project
Raine, A., Venables, P. H., Dalais, C., Mellingen, K., Reynolds, C., & Mednick, S. A. (2001) · Psychophysiology · doi:10.1111/1469-8986.3820254 · Cited by 195 · see citing works
Origins and Consequences of Age at First Drink. II. Familial Risk and Heritability
McGue, M. K., Iacono, W. G., Legrand, L. N., & Elkins, I. J. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02331.x · Cited by 194 · see citing works
Scared Straight and Other Juvenile Awareness Programs for Preventing Juvenile Delinquency: A Systematic Review of the Randomized Experimental Evidence
Petrosino, A. J., Turpin‐Petrosino, C., & Buehler, J. (2003) · The Annals of the American Academy of Political and Social Science · doi:10.1177/0002716203254693 · Cited by 194 · see citing works
Rational-emotive therapy and cognitive behavior therapy: similarities and differences
Ellis, A. (1980) · Cognitive Therapy and Research · doi:10.1007/bf01178210 · Cited by 182 · see citing works
A mediational model for boys' depressed mood
Patterson, G. R., & Capaldi, D. M. (1990) · Cambridge University Press eBooks · doi:10.1017/cbo9780511752872.010 · Cited by 180 · see citing works
Genetic and environmental bases of childhood antisocial behavior: A multi-informant twin study.
Baker, L. A., Jacobson, K. C., Raine, A., Lozano, D. I., & Bezdjian, S. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.2.219 · Cited by 178 · see citing works
Treating and Preventing Adolescent Mental Health Disorders
(2005) · Oxford University Press eBooks · doi:10.1093/9780195173642.001.0001 · Cited by 175 · see citing works
Confirming the latent structure and base rate of schizotypy: A taxometric analysis.
Lenzenweger, M. F., & Korfine, L. (1992) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.101.3.567 · Cited by 174 · see citing works
Alterations in reward-related decision making in boys with recent and future depression
Forbes, E. E., Shaw, D. S., & Dahl, R. E. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.026 · Cited by 173 · see citing works
Genetic effects on the variation and covariation of attention deficit-hyperactivity disorder (ADHD) and oppositional-defiant disorder/conduct disorder (ODD/CD) symptomatologies across informant and occasion of measurement
NADDER, T. S., RUTTER, M., SILBERG, J. L., MAES, H. H., & EAVES, L. J. (2002) · Psychological Medicine · doi:10.1017/s0033291701004792 · Cited by 172 · see citing works
The role of child adrenocortical functioning in pathways between interparental conflict and child maladjustment.
Davies, P. T., Sturge-Apple, M. L., Cicchetti, D., & Cummings, E. M. (2007) · Developmental Psychology · doi:10.1037/0012-1649.43.4.918 · Cited by 171 · see citing works
Physiologic Responses to Sudden, Loud Tones in Monozygotic Twins Discordant for Combat Exposure Association With Posttraumatic Stress Disorder
Orr, S. P. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.3.283 · Cited by 170 · see citing works
Personality disorders in early adolescence and the development of later substance use disorders in the general population
Cohen, P. R., Chen, H., Crawford, T. N., Brook, J. S., & Gordon, K. (2007) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.12.012 · Cited by 167 · see citing works
Effects of dialectic-behavioral-therapy on the neural correlates of affective hyperarousal in borderline personality disorder
Schnell, K., & Herpertz, S. C. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.08.011 · Cited by 166 · see citing works
Validation of a system of classifying female substance abusers on the basis of personality and motivational risk factors for substance abuse.
Conrod, P., Pihl, R. O., Stewart, S. H., et al. (2000) · Psychology of Addictive Behaviors · doi:10.1037/0893-164x.14.3.243 · Cited by 165 · see citing works
Taxometrics and developmental psychopathology
Beauchaine, T. P. (2003) · Development and Psychopathology · doi:10.1017/s0954579403000270 · Cited by 160 · see citing works
Self-citation
Familial and temperamental predictors of resilience in children at risk for conduct disorder and depression
Shannon, K. E., Beauchaine, T. P., Brenner, S. L., Neuhaus, E., & Gatzke‐Kopp, L. M. (2007) · Development and Psychopathology · doi:10.1017/s0954579407000351 · Cited by 157 · see citing works
Self-citation
Multilevel perspectives on pathways to resilient functioning
Cicchetti, D., & Curtis, W. J. (2007) · Development and Psychopathology · doi:10.1017/s0954579407000314 · Cited by 156 · see citing works
Detection of the schizoid taxon with MMPI indicators.
Golden, R. R., & Meehl, P. E. (1979) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.88.3.217 · Cited by 156 · see citing works
Evaluation of indicated suicide risk prevention approaches for potential high school dropouts.
Thompson, E. A., Eggert, L. L., Randell, B. P., & Pike, K. (2001) · American Journal of Public Health · doi:10.2105/ajph.91.5.742 · Cited by 155 · see citing works
A Dual-Deficit Model of Psychopathy.
Fowles, D. C., & Dindo, L. N. (2006) · Cited by 153 · see citing works
Early father involvement moderates biobehavioral susceptibility to mental health problems in middle childhood
BOYCE, W. T., ESSEX, M. J., ALKON, A., GOLDSMITH, H. H., KRAEMER, H. C., & KUPFER, D. J. (2006) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000237706.50884.8b · Cited by 150 · see citing works
Parent-child interactions, peripheral serotonin, and self-inflicted injury in adolescents.
Crowell, S. E., Beauchaine, T. P., McCauley, E., Smith, C. J., Vasilev, C. A., & Stevens, A. L. (2008) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.76.1.15 · Cited by 150 · see citing works
Self-citation
Depressive symptoms in children and adolescents: changing aetiological influences with development
Scourfield, J., Rice, F. J., Thapar, A., Harold, G. T., Martin, N. C., & McGuffin, P. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00181 · Cited by 148 · see citing works
Genetic and environmental influences on the temporal association between earlier anxiety and later depression in girls
Silberg, J. L., Rutter, M. L., & Eaves, L. J. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01161-1 · Cited by 145 · see citing works
Differential Sensitivity to Alcohol Reinforcement in Groups of Men at Risk for Distinct Alcoholism Subtypes
Conrod, P., Pihl, R. O., & Vassileva, J. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb04297.x · Cited by 144 · see citing works
Co-occurrence of depressive symptoms and antisocial behavior in adolescence: A common genetic liability.
O’Connor, T. G., McGuire, S. A., Reiss, D., et al. (1998) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.107.1.27 · Cited by 144 · see citing works
Schizotaxia, schizotypy, and schizophrenia: Paul E. Meehl's blueprint for the experimental psychopathology and genetics of schizophrenia.
Lenzenweger, M. F. (2006) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.115.2.195 · Cited by 141 · see citing works
Vagal tone protects children from marital conflict
Katz, L. F., & Gottman, J. M. (1995) · Development and Psychopathology · doi:10.1017/s0954579400006350 · Cited by 138 · see citing works
Neurological correlates of reward responding in adolescents with and without externalizing behavior disorders
Gatzke-Kopp, L. M., Beauchaine, T. P., Shannon, K. E., Chipman, J., Fleming, A. P., Crowell, S. E., Liang, O., Johnson, L. C., & Aylward, E. (2009) · Journal of Abnormal Psychology · doi:10.1037/a0014378 · Cited by 137 · see citing works
Self-citation
The Developing Brain and Neural Plasticity: Implications for Normality, Psychopathology,and Resilience
Cicchetti, D., & Curtis, W. J. (2015) · Wiley eBooks · doi:10.1002/9780470939390.ch1 · Cited by 136 · see citing works
Treatment of the schizophrenia prodrome: is it presently ethical?
Cornblatt, B. A., Lencz, T., & Kane, J. M. (2001) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00236-5 · Cited by 135 · see citing works
Reward sensitivity in depression: A biobehavioral study.
Shankman, S. A., Klein, D. N., Tenke, C. E., & Bruder, G. E. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.1.95 · Cited by 132 · see citing works
Genetic and social influences on starting to smoke: a study of Dutch adolescent twins and their parents
Boomsma, D. I., Koopmans, J. R., van Doornen, L. J. P., & Orlebeke, J. F. (1994) · Addiction · doi:10.1111/j.1360-0443.1994.tb00881.x · Cited by 130 · see citing works
Evidence for multiple loci from a genome scan of autism kindreds
Schellenberg, G. D., Dawson, G., Sung, Y. J., Estes, A., Munson, J., Rosenthal, E., Rothstein, J., Flodman, P., Smith, M., Coon, H., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001874 · Cited by 129 · cited 2× · see citing works
“…theresultof inadequateparenting (Klinger, Dawson, & Renner, 2003), autism spectrum disorders are now recognized to stem from multiple genes (Schellenberg et al., 2006), yet early environmental interventions for those exhibiting endophenotypic markers of risk offer pro- found protective…”
Background
Association between Alcohol Use and Smoking in Adolescent and Young Adult Twins: A Bivariate Genetic Analysis
Koopmans, J. R., van Doornen, L. J. P., & Boomsma, D. I. (1997) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1997.tb03800.x · Cited by 129 · see citing works
Hedonic capacity and schizotypy revisited: A taxometric analysis of social anhedonia.
Blanchard, J. J., Gangestad, S. W., Brown, S. A., & Horan, W. P. (2000) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.109.1.87 · Cited by 128 · see citing works
Differential heritability of eating attitudes and behaviors in prepubertal versus pubertal twins
Klump, K. L., McGue, M. K., & Iacono, W. G. (2003) · International Journal of Eating Disorders · doi:10.1002/eat.10151 · Cited by 127 · see citing works
Confirming the latent structure and base rate of schizotypy: A taxometric analysis.
Lenzenweger, M. F., & Korfine, L. (1992) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.101.3.567 · Cited by 127 · see citing works
Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD
Kent, L., Green, E., Hawi, Z., Kirley, A., Dudbridge, F., Lowe, N., Raybould, R., Langley, K., Bray, N., Fitzgerald, M., et al. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001696 · Cited by 125 · see citing works
An integrative, multidisciplinary approach to the study of brain–behavior relations in the context of typical and atypical development
NELSON, C. A., BLOOM, F. E., CAMERON, J. L., AMARAL, D., DAHL, R. E., & PINE, D. (2002) · Development and Psychopathology · doi:10.1017/s0954579402003061 · Cited by 124 · see citing works
Early adversity and mechanisms of plasticity: Integrating affective neuroscience with developmental approaches to psychopathology
Pollak, S. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050352 · Cited by 121 · see citing works
Essentialism revisited: Evolutionary theory and the concept of mental disorder.
Lilienfeld, S. O., & Marino, L. (1999) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.108.3.400 · Cited by 118 · see citing works
The taxonicity of schizotypy: A replication.
Korfine, L., & Lenzenweger, M. F. (1995) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.104.1.26 · Cited by 117 · see citing works
Group parent training: Is it effective for children of all ages?
Ruma, P. R., Burke, R. V., & Thompson, R. W. (1996) · Behavior Therapy · doi:10.1016/s0005-7894(96)80012-8 · Cited by 117 · see citing works
Origins of Antisocial Behavior
Snyder, J. J., Schrepferman, L., & Peter, C. C. S. (1997) · Behavior Modification · doi:10.1177/01454455970212004 · Cited by 115 · see citing works
The Importance of Neurobiological Research to the Prevention of Psychopathology
Fishbein, D. H. (2000) · Prevention Science · doi:10.1023/a:1010090114858 · Cited by 113 · see citing works
Eating Disorder Prevention Research: A Meta-Analysis
Fingeret, M. C., Warren, C. S., Antonio Cepeda-benito, A., & Gleaves, D. H. (2006) · Eating Disorders · doi:10.1080/10640260600638899 · Cited by 113 · see citing works

Flagged first, then by citations

Research works printed but not linked: 7

Beauchaine TP Hinshaw SP Gatzke-Kopp L 2008 Genetic and environmental influences on behavior Beauchaine TP Hinshaw SP Child psychopathology: Genetic, neurobiological, and environmental substrates 58 91 Hoboken, NJ Wiley
Beauchaine TP Mead HK 2006 Some recommendations for testing mediating and moderating effects in treatment-outcome research International Journal of Psychology Research 1 1
Beauchaine TP Neuhaus E 2008 Behavioral disinhibition and vulnerability to psychopathology Beauchaine TP Hinshaw SP Child psychopathology: Genetic, neurobiological, and environmental substrates 129 156 Hoboken, NJ Wiley
Crowell SE Beauchaine TP Lenzenweger M 2008 The development of borderline personality and self-injurious behavior Beauchaine TP Hinshaw S Child psychopathology: Genetic, neurobiological, and environmental substrates 510 541 Hoboken, NJ Wiley
Fryer SL Crocker NA Mattson SN 2008 Exposure to teratogenic agents as a risk factor for psychopathology Beauchaine TP Hinshaw SP Child psychopathology: Genetic, neurobiological, and environmental substrates 180 207 Hoboken, NJ Wiley
Klein DN Torpey DC Bufferd SJ Dyson MW 2008 Depressive disorders Beauchaine TP Hinshaw SP Child and adolescent psychopathology 477 509 Hoboken, NJ Wiley
Perry BD 2008 Child maltreatment: A neurodevelopmental perspective on the role of abuse and neglect in Psychopathology Beauchaine TP Hinshaw SP Child psychopathology: Genetic, neurobiological, and environmental substrates 93 128 Hoboken, NJ Wiley

Sorted by citations

A biosocial developmental model of borderline personality: Elaborating and extending linehan’s theory.
Crowell, S. E., Beauchaine, T. P., & Linehan, M. M. (2009) · Psychological Bulletin · doi:10.1037/a0015616 · Cited by 1,292 · see citing works
Self-citation
Heart rate variability as a transdiagnostic biomarker of psychopathology
Beauchaine, T. P., & Thayer, J. F. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.08.004 · Cited by 870 · see citing works
Self-citation
Future Directions in Emotion Dysregulation and Youth Psychopathology
Beauchaine, T. P. (2015) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2015.1038827 · Cited by 394 · see citing works
Self-citation
Developmental phenotypes and causal pathways in attention deficit/hyperactivity disorder: potential targets for early intervention?
Sonuga‐Barke, E. J. S., & Halperin, J. M. (2010) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2009.02195.x · Cited by 320 · see citing works
Combining Parent and Child Training for Young Children with ADHD
Webster-Stratton, C. H., Reid, M. J., & Beauchaine, T. (2011) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2011.546044 · Cited by 265 · see citing works
Self-citation
Adolescent neurobiological susceptibility to social context
Schriber, R. A., & Guyer, A. E. (2016) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.12.009 · Cited by 246 · see citing works
Children’s externalizing and internalizing symptoms over time: The role of individual differences in patterns of RSA responding
Hinnant, J. B., & El-Sheikh, M. (2009) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-009-9341-1 · Cited by 167 · see citing works
Suicide-related behaviors and anxiety in children and adolescents: a review
Hill, R. M., Castellanos, D., & Pettit, J. W. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.07.008 · Cited by 124 · see citing works
Neurobiological correlates of social functioning in autism
Neuhaus, E., Beauchaine, T. P., & Bernier, R. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.05.007 · Cited by 122 · see citing works
Self-citation
Neural responses to monetary incentives among self-injuring adolescent girls
Sauder, C. L., Derbidge, C. M., & Beauchaine, T. P. (2016) · Development and Psychopathology · doi:10.1017/s0954579415000449 · Cited by 89 · see citing works
Self-citation
Marital conflict, respiratory sinus arrhythmia, and allostatic load: Interrelations and associations with the development of children's externalizing behavior
El-Sheikh, M., & Hinnant, J. B. (2011) · Development and Psychopathology · doi:10.1017/s0954579411000320 · Cited by 84 · see citing works
Nonsuicidal self-injury and suicidal behaviors in girls: The case for targeted prevention in preadolescence
Beauchaine, T. P., Hinshaw, S. P., & Bridge, J. A. (2019) · Clinical Psychological Science · doi:10.1177/2167702618818474 · Cited by 80 · see citing works
Self-citation
Bifactor latent structure of attention-deficit/hyperactivity disorder (ADHD)/oppositional defiant disorder (ODD) symptoms and first-order latent structure of sluggish cognitive tempo symptoms
Lee, S., Burns, G. L., Beauchaine, T. P., & Becker, S. P. (2016) · Psychological Assessment · doi:10.1037/pas0000232 · Cited by 54 · see citing works
Self-injuring adolescent girls exhibit insular cortex volumetric abnormalities that are similar to those seen in adults with borderline personality disorder
Beauchaine, T. P., Sauder, C. L., Derbidge, C. M., & Uyeji, L. L. (2019) · Development and Psychopathology · doi:10.1017/s0954579418000822 · Cited by 49 · see citing works
Self-citation
Prediction of caseness for mental pathology in Swiss conscripts: the self-screen prodrome
Mueller, M., Riecher, A., Kammermann, J., Stieglitz, R. D., Stettbacher, G. A., & Vetter, S. (2009) · Military Medicine · doi:10.7205/milmed-d-04-8808 · Cited by 11 · see citing works

Authors: Beauchaine, T. P., Neuhaus, E., Brenner, S. L., & Gatzke-Kopp, L.
Affiliations: University of Washington (US)
Corresponding author: Beauchaine, Theodore P.
ORCID: Beauchaine, Theodore P.
Neuhaus, Emily
Venue: Development and Psychopathology
Publisher: Cambridge University Press (CUP)
Published: 2008
Volume: 20
Issue: 3
Pages: 745-774
ISSN: 0954-5794 (ISSN-L)
1469-2198
DOI: 10.1017/s0954579408000369
PMC: PMC2690981
OpenAlex: W2172045957
Cited by: 215
References: 282
Citations by year: 2026: 2 · 2025: 5 · 2024: 7 · 2023: 7 · 2022: 8 · 2021: 16 · 2020: 13 · 2019: 9 · 2018: 14 · 2017: 18 · 2016: 14 · 2015: 20 · 2014: 12 · 2013: 18 · 2012: 16
FWCI: 2.07
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.cambridge.org/core/terms (unspecified, 188 d)
Locations: Development and Psychopathology (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health (R01MH063699, MH63699)
Topics: Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: biological processes, prevention research, intervention research, developmental psychopathology, genetic etiology, neurobiological mechanisms, biomarkers, endophenotypes, psychiatric comorbidity, heterotypic continuity, gene-environment interaction, epigenesis, neuroplasticity, biological vulnerability, treatment efficacy
MeSH terms: Adolescent, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Brain, Child, Child, Preschool, Depressive Disorder, Female, Humans, Infant, Infant, Newborn, Neuronal Plasticity, Phenotype, Pregnancy, Prenatal Exposure Delayed Effects, Psychopathology, Risk Factors, Schizophrenia, Schizophrenic Psychology, Social Environment, Neurotransmitter Agents, Twin Studies as Topic, Conduct Disorder, Genetic Predisposition to Disease, Early Diagnosis

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