The development of neural stem cells

Mammalian neural stem cells.

Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 4,786

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

Cattaneo, E., & McKay, R. (1990) · Nature · doi:10.1038/347762a0 · Cited by 717

Astroglia induce neurogenesis from adult neural stem cells

Song, H., Stevens, C. F., & Gage, F. H. (2002) · Nature · doi:10.1038/417039a · Cited by 1,452

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

Imayoshi, I., Sakamoto, M., Ohtsuka, T., Takao, K., Miyakawa, T., Yamaguchi, M., Mori, K., Ikeda, T., Itohara, S., & Kageyama, R. (2008) · Nature Neuroscience · doi:10.1038/nn.2185 · Cited by 1,054

Development of the human cerebral cortex: Boulder Committee revisited

Bystron, I., Blakemore, C., & Rakic, P. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2252 · Cited by 977

REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis

Ballas, N., Grunseich, C., Lu, D. D., Speh, J. C., & Mandel, G. (2005) · Cell · doi:10.1016/j.cell.2005.03.013 · Cited by 950

In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics

Bonaguidi, M. A., Wheeler, M. A., Shapiro, J. S., Stadel, R. P., Sun, G. J., Ming, G.-L., & Song, H. (2011) · Cell · doi:10.1016/j.cell.2011.05.024 · Cited by 831

An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development

Lessard, J., Wu, J. I., Ranish, J. A., Wan, M., Winslow, M. M., Staahl, B. T., Wu, H., Aebersold, R., Graef, I. A., & Crabtree, G. R. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.019 · Cited by 735

The glial identity of neural stem cells

Doetsch, F. (2003) · Nature Neuroscience · doi:10.1038/nn1144 · Cited by 724

Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains

Imayoshi, I., Sakamoto, M., Yamaguchi, M., Mori, K., & Kageyama, R. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4987-09.2010 · Cited by 716

Excitation-Neurogenesis Coupling in Adult Neural Stem/Progenitor Cells

Deisseroth, K., Singla, S., Toda, H., Monje, M., Palmer, T. D., & Malenka, R. C. (2004) · Neuron · doi:10.1016/s0896-6273(04)00266-1 · Cited by 674

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

Yoo, A. S., Staahl, B. T., Chen, L., & Crabtree, G. R. (2009) · Nature · doi:10.1038/nature08139 · Cited by 645

The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells

Hirabayashi, Y., Itoh, Y., Tabata, H., Nakajima, K., Akiyama, T., Masuyama, N., & Gotoh, Y. (2004) · Development · doi:10.1242/dev.01165 · Cited by 600

Cancer stem cells in nervous system tumors

Singh, S. K., Clarke, I. D., Hide, T., & Dirks, P. B. (2004) · Oncogene · doi:10.1038/sj.onc.1207946 · Cited by 569

Extracellular Matrix: Functions in the Nervous System

Barros, C. S., Franco, S. J., & Muller, U. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005108 · Cited by 506

Embryonic origin of postnatal neural stem cells

Fuentealba, L. C., Rompani, S. B., Parraguez, J. I., Obernier, K., Romero, R., Cepko, C. L., & Alvarez-Buylla, A. (2015) · Cell · doi:10.1016/j.cell.2015.05.041 · Cited by 488

Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4

Chen, Z., Jalabi, W., Shpargel, K. B., Farabaugh, K. T., Dutta, R., Yin, X., Kidd, G. J., Bergmann, C. C., Stohlman, S. A., & Trapp, B. D. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0730-12.2012 · Cited by 432

DNA methylation: An epigenetic mark of cellular memory

Kim, M., & Costello, J. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.10 · Cited by 450

CNS Microvascular Pericytes Exhibit Multipotential Stem Cell Activity

Dore-Duffy, P., Katychev, A., Wang, X., & Van Buren, E. (2006) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600272 · Cited by 414

Docosahexaenoic acid promotes neurogenesis in vitro and in vivo

Kawakita, E., Hashimoto, M., & Shido, O. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.01.021 · Cited by 410

Epigenetic regulation of gene expression in physiological and pathological brain processes

Gräff, J., Kim, D., Dobbin, M. M., & Tsai, L.-H. (2011) · Physiological Reviews · doi:10.1152/physrev.00012.2010 · Cited by 373

Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration

Wei, X., Fu, S., Li, H., Liu, Y., Wang, S., Feng, W., Yang, Y., Liu, X., Zeng, Y.-Y., Cheng, M., et al. (2022) · Science · doi:10.1126/science.abp9444 · Cited by 311

Spatial and temporal specification of neural fates by transcription factor codes

Guillemot, F. (2007) · Development · doi:10.1242/dev.006379 · Cited by 308

The lighter side of BDNF

Noble, E. E., Billington, C. J., Kotz, C. M., & Wang, C. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00776.2010 · Cited by 284

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development

Naka, H., Nakamura, S., Shimazaki, T., & Okano, H. (2008) · Nature Neuroscience · doi:10.1038/nn.2168 · Cited by 243

Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells

Nakamura, M., & Okano, H. (2013) · Cell Research · doi:10.1038/cr.2012.171 · Cited by 214

A crucial role for Olig2 in white matter astrocyte development

Cai, J., Chen, Y., Cai, W.-H., Hurlock, E. C., Wu, H., Kernie, S. G., Parada, L. F., & Lu, Q. R. (2007) · Development · doi:10.1242/dev.02847 · Cited by 203

Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing

Wu, J. Q., Habegger, L., Noisa, P., Szekely, A., Qiu, C., Hutchison, S., Raha, D., Egholm, M., Lin, H., Weissman, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914114107 · Cited by 189

Circumventricular organs: A novel site of neural stem cells in the adult brain

Bennett, L., Yang, M., Enikolopov, G., & Iacovitti, L. (2009) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2009.04.007 · Cited by 186

Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells

Ferrón, S., Mira, H., Franco, S., Cano-Jaimez, M., Bellmunt, E., Ramírez, C., Fariñas, I., & Blasco, M. A. (2004) · Development · doi:10.1242/dev.01215 · Cited by 152

RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity

Muraguchi, T., Takegami, Y., Ohtsuka, T., Kitajima, S., Chandana, E. P. S., Omura, A., Miki, T., Takahashi, R., Matsumoto, N., Ludwig, A., et al. (2007) · Nature Neuroscience · doi:10.1038/nn1922 · Cited by 149

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind

Hsieh, J., & Eisch, A. J. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.01.008 · Cited by 144

3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity

Papadimitriou, C., Celikkaya, H., Cosacak, M. I., Mashkaryan, V., Bray, L., Bhattarai, P., Brandt, K., Hollak, H., Chen, X., He, S., et al. (2018) · Developmental Cell · doi:10.1016/j.devcel.2018.06.005 · Cited by 143

Single-cell transcriptomics analyses of neural stem cell heterogeneity and contextual plasticity in a zebrafish brain model of amyloid toxicity

Cosacak, M. I., Bhattarai, P., Reinhardt, S., Petzold, A., Dahl, A., Zhang, Y., & Kizil, C. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.03.090 · Cited by 116

Remyelinating strategies for the treatment of multiple sclerosis

Stangel, M., & Hartung, H.-P. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00105-3 · Cited by 126

The neurovascular unit and its growth factors: coordinated response in the vascular and nervous systems

Ward, N. L., & Lamanna, J. C. (2004) · Neurological Research · doi:10.1179/016164104x3798 · Cited by 122

The role of Notch signaling in adult neurogenesis

Imayoshi, I., & Kageyama, R. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8186-0 · Cited by 102

Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair

Li, M., Hale, J. S., Rich, J. N., Ransohoff, R. M., & Lathia, J. D. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.06.003 · Cited by 104

The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord

Petracca, Y. L., Sartoretti, M. M., Di Bella, D. J., Marin-Burgin, A., Carcagno, A. L., Schinder, A. F., & Lanuza, G. M. (2016) · Development · doi:10.1242/dev.129254 · Cited by 90

Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1

Oishi, K., Watatani, K., Itoh, Y., Okano, H., Guillemot, F., Nakajima, K., & Gotoh, Y. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808400106 · Cited by 75

Tcf3 Represses Wnt–β-Catenin Signaling and Maintains Neural Stem Cell Population during Neocortical Development

Kuwahara, A., Sakai, H., Xu, Y., Itoh, Y., Hirabayashi, Y., & Gotoh, Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094408 · Cited by 66

M2 Phenotype Microglia-derived Cytokine Stimulates Proliferation and Neuronal Differentiation of Endogenous Stem Cells in Ischemic Brain

Choi, J. Y., Kim, J. Y., Kim, J. Y., Park, J., Lee, W. T., & Lee, J. E. (2017) · Experimental Neurobiology · doi:10.5607/en.2017.26.1.33 · Cited by 65

The role of neural stem cells in regulating glial scar formation and repair

Nicaise, A. M., D’Angelo, A., Ionescu, R.-B., Krzak, G., Willis, C. M., & Pluchino, S. (2022) · Cell and Tissue Research · doi:10.1007/s00441-021-03554-0 · Cited by 65

Brain homeostasis: VEGF receptor 1 and 2—two unequal brothers in mind

Wittko-Schneider, I. M., Schneider, F. T., & Plate, K. H. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1279-3 · Cited by 62

Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells

Rhim, J. H., Luo, X., Gao, D., Xu, X., Zhou, T., Li, F., Wang, P., Wong, S. T. C., & Xia, X. (2016) · Scientific Reports · doi:10.1038/srep26547 · Cited by 42

CHL1 negatively regulates the proliferation and neuronal differentiation of neural progenitor cells through activation of the ERK1/2 MAPK pathway.

Huang, X., Zhu, L.-L., Zhao, T., Wu, L.-Y., Wu, K.-W., Schachner, M., Xiao, Z.-C., & Fan, M. (2011) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.09.013 · Cited by 35

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles

Santos, T., Ferreira, R., Quartin, E., Boto, C., Saraiva, C., Bragança, J., Peça, J., Rodrigues, C., Ferreira, L., & Bernardino, L. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.06.044 · Cited by 26

Roles of angiopoietin-like proteins in regulation of stem cell activity

Kadomatsu, T., & Oike, Y. (2019) · The Journal of Biochemistry · doi:10.1093/jb/mvz005 · Cited by 23

A neural extracellular matrix-based method for in vitrohippocampal neuron culture and dopaminergic differentiation of neural stem cells

García-Parra, P., Maroto, M., Cavaliere, F., Naldaiz-Gastesi, N., Álava, J. I., García, A. G., López de Munain, A., & Izeta, A. (2013) · BMC Neuroscience · doi:10.1186/1471-2202-14-48 · Cited by 16

Gene delivery targeted to oligodendrocytes using a lentiviral vector: Gene delivery to oligodendrocytes

Kagiava, A., Sargiannidou, I., Bashiardes, S., Richter, J., Schiza, N., Christodoulou, C., Gritti, A., & Kleopa, K. A. (2014) · The Journal of Gene Medicine · doi:10.1002/jgm.2813 · Cited by 12