Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

A role for brown adipose tissue in diet-induced thermogenesis

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Thermogenic mechanisms in brown fat.

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

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A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

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Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator

Puigserver, P., & Spiegelman, B. M. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0012 · Cited by 2,076

The PPARs: From Orphan Receptors to Drug Discovery

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Towards a molecular understanding of adaptive thermogenesis

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Mitochondria in innate immune responses

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Mitochondrial ROS Signaling in Organismal Homeostasis

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Mitochondria and neuronal survival

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Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Klaman, L. D., Boss, O., Peroni, O. D., Kim, J. K., Martino, J. L., Zabolotny, J. M., Moghal, N., Lubkin, M., Kim, Y.-B., Sharpe, A. H., et al. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.15.5479-5489.2000 · Cited by 1,235

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J.-M., Lee, C. H., Oh, W. K., Kim, C. T., et al. (2006) · Diabetes · doi:10.2337/db06-0006 · Cited by 1,054

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β-cell dysfunction, and type 2 diabetes.

Zhang, C.-Y., Baffy, G., Perret, P., Krauss, S., Peroni, O., Grujic, D., Hagen, T., Vidal-Puig, A. J., Boss, O., Kim, Y.-B., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00378-6 · Cited by 917

Uncoupling: new approaches to an old problem of bioenergetics

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Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3

Brand, M. D., & Esteves, T. C. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.06.002 · Cited by 785

Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

Sivitz, W. I., & Yorek, M. A. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2531 · Cited by 742

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells

Bordone, L., Motta, M. C., Picard, F., Robinson, A., Jhala, U. S., Apfeld, J., McDonagh, T., Lemieux, M., McBurney, M., Szilvasi, A., et al. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0040031 · Cited by 715

Thermogenic Mechanisms and Their Hormonal Regulation

Silva, J. E. (2006) · Physiological Reviews · doi:10.1152/physrev.00009.2005 · Cited by 687

Energy metabolism in uncoupling protein 3 gene knockout mice

Vidal-Puig, A. J., Grujic, D., Zhang, C.-Y., Hagen, T., Boss, O., Ido, Y., Szczepanik, A., Wade, J., Mootha, V., Cortright, R., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m910179199 · Cited by 677

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.

Guerra, C., Koza, R. A., Yamashita, H., Walsh, K., & Kozak, L. P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3155 · Cited by 635

UCP1: The only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency

Nedergaard, J., Golozoubova, V., Matthias, A., Asadi, A., Jacobsson, A., & Cannon, B. (2001) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00247-4 · Cited by 615

Mitochondrial uncoupling, ROS generation and cardioprotection

Cadenas, S. (2018) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2018.05.019 · Cited by 591

Transgenic Mice Expressing Human Fibroblast Growth Factor-19 Display Increased Metabolic Rate and Decreased Adiposity

Tomlinson, E., Fu, L., John, L., Hultgren, B., Huang, X., Renz, M., Stephan, J. P., Tsai, S. P., Powell-Braxton, L., French, D., et al. (2002) · Endocrinology · doi:10.1210/endo.143.5.8850 · Cited by 576

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

Mattiasson, G., Shamloo, M., Gido, G., Mathi, K., Tomasevic, G., Yi, S., Warden, C. H., Castilho, R. F., Melcher, T., Gonzalez-Zulueta, M., et al. (2003) · Nature Medicine · doi:10.1038/nm903 · Cited by 515

Effect of Exercise Intensity, Duration and Mode on Post-Exercise Oxygen Consumption

B??rsheim, E., & Bahr, R. (2003) · Sports Medicine · doi:10.2165/00007256-200333140-00002 · Cited by 466

Mitochondrial H + Leak and ROS Generation: An Odd Couple

Brookes, P. S. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.10.016 · Cited by 447

Medicinal strategies in the treatment of obesity

Bray, G. A., & Tartaglia, L. A. (2000) · Nature · doi:10.1038/35007544 · Cited by 432

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

Vozza, A., Parisi, G., De Leonardis, F., Lasorsa, F. M., Castegna, A., Amorese, D., Marmo, R., Calcagnile, V. M., Palmieri, L., Ricquier, D., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1317400111 · Cited by 407

Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side

Echtay, K. S., Murphy, M. P., Smith, R. A. J., Talbot, D. A., & Brand, M. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m208262200 · Cited by 388

Brain temperature and its fundamental properties: a review for clinical neuroscientists

Wang, H., Wang, B., Normoyle, K. P., Jackson, K., Spitler, K., Sharrock, M. F., Miller, C. M., Best, C., Llano, D., & Du, R. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00307 · Cited by 356

Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion

Chan, C. B., De Leo, D., Joseph, J. W., McQuaid, T. S., Ha, X. F., Xu, F., Tsushima, R. G., Pennefather, P. S., Salapatek, A. M. F., & Wheeler, M. B. (2001) · Diabetes · doi:10.2337/diabetes.50.6.1302 · Cited by 341

Transport function and regulation of mitochondrial uncoupling proteins 2 and 3

Jabůrek, M., Vařecha, M., Gimeno, R. E., Dembski, M., Ježek, P., Zhang, M., Burn, P., Tartaglia, L. A., & Garlid, K. D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.26003 · Cited by 321

Uncoupling Protein-2 Overexpression Inhibits Mitochondrial Death Pathway in Cardiomyocytes

Teshima, Y., Akao, M., Jones, S. P., & Marbán, E. (2003) · Circulation Research · doi:10.1161/01.res.0000085581.60197.4d · Cited by 318

Uncoupling proteins 2 and 3 are highly active H + transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

Echtay, K. S., Winkler, E., Frischmuth, K., & Klingenberg, M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1416 · Cited by 313

Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension

Hansell, P., Welch, W. J., Blantz, R. C., & Palm, F. (2013) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12034 · Cited by 269

Mitochondrial uncoupling as a target for drug development for the treatment of obesity.

Harper, J. A., Dickinson, K., & Brand, M. D. (2001) · Obesity Reviews · doi:10.1046/j.1467-789x.2001.00043.x · Cited by 250

Regulation of leptin production: sympathetic nervous system interactions

Rayner, D. V., & Trayhurn, P. (2001) · Journal of Molecular Medicine · doi:10.1007/s001090100198 · Cited by 250

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

Chan, C. B., MacDonald, P. E., Saleh, M. C., Johns, D. C., Marbàn, E., & Wheeler, M. B. (1999) · Diabetes · doi:10.2337/diabetes.48.7.1482 · Cited by 242

Microglial UCP2 mediates inflammation and obesity induced by high-fat feeding

Kim, J. D., Yoon, N. A., Jin, S., & Diano, S. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.08.010 · Cited by 240

UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged

Cadenas, S., Buckingham, J. A., Samec, S., Seydoux, J., Din, N., Dulloo, A. G., & Brand, M. D. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01540-9 · Cited by 227

Physiological Increases in Uncoupling Protein 3 Augment Fatty Acid Oxidation and Decrease Reactive Oxygen Species Production Without Uncoupling Respiration in Muscle Cells

MacLellan, J. D., Gerrits, M. F., Gowing, A., Smith, P. J. S., Wheeler, M. B., & Harper, M.-E. (2005) · Diabetes · doi:10.2337/diabetes.54.8.2343 · Cited by 213

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization

Pecqueur, C., Bui, T., Gelly, C., Hauchard, J., Barbot, C., Bouillaud, F., Ricquier, D., Miroux, B., & Thompson, C. B. (2008) · The FASEB Journal · doi:10.1096/fj.07-8945com · Cited by 209

Mitochondrial Uncoupling: A Key Contributor to Reduced Cardiac Efficiency in Diabetes

Boudina, S., & Abel, E. D. (2006) · Physiology · doi:10.1152/physiol.00008.2006 · Cited by 199

Uncoupling Protein-2 Is Critical for Nigral Dopamine Cell Survival in a Mouse Model of Parkinson's Disease

Andrews, Z. B., Horvath, B., Barnstable, C. J., Elseworth, J., Yang, L., Beal, M. F., Roth, R. H., Matthews, R. T., & Horvath, T. L. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4269-04.2005 · Cited by 199

Fatty acid cycling mechanism and mitochondrial uncoupling proteins

Ježek, P., Engstová, H., Žáčková, M., Vercesi, A. E., Costa, A. D. T., Arruda, P., & Garlid, K. D. (1998) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(98)00084-x · Cited by 196

Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins

Cusin, I., Zakrzewska, K. E., Boss, O., Muzzin, P., Giacobino, J. P., Ricquier, D., Jeanrenaud, B., & Rohner-Jeanrenaud, F. (1998) · Diabetes · doi:10.2337/diabetes.47.7.1014 · Cited by 190

Obesity, diabetes and the central nervous system

Porte Jr., D., Seeley, R. J., Woods, S. C., Baskin, D. G., Figlewicz, D. P., & Schwartz, M. W. (1998) · Diabetologia · doi:10.1007/s001250051002 · Cited by 186

Dietary n-3 fatty acids affect mRNA level of brown adipose tissue uncoupling protein 1, and white adipose tissue leptin and glucose transporter 4 in the rat

Takahashi, Y., & Ide, T. (2000) · British Journal of Nutrition · doi:10.1017/s0007114500001409 · Cited by 175

A Reservoir of Brown Adipocyte Progenitors in Human Skeletal Muscle

Crisan, M., Casteilla, L., Lehr, L., Carmona, M., Paoloni-Giacobino, A., Yap, S., Sun, B., Léger, B., Logar, A., Pénicaud, L., et al. (2008) · Stem Cells · doi:10.1634/stemcells.2008-0325 · Cited by 172

An alternative function for human uncoupling protein 3: protection of mitochondria against accumulation of nonesterified fatty acids inside the mitochondrial matrix

SCHRAUWEN, P., SARIS, W. H. M., & HESSELINK, M. K. C. (2001) · The FASEB Journal · doi:10.1096/fj.01-0400hyp · Cited by 172

Mitochondrial uncoupling and lifespan

Mookerjee, S. A., Divakaruni, A. S., Jastroch, M., & Brand, M. D. (2010) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2010.03.010 · Cited by 169

Mitochondrial proton leak and the uncoupling protein 1 homologues

Stuart, J. A., Cadenas, S., Jekabsons, M. B., Roussel, D., & Brand, M. D. (2001) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00243-7 · Cited by 169

Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic β-cell function.

Pi, J., Bai, Y., Daniel, K. W., Liu, D., Lyght, O., Edelstein, D., Brownlee, M., Corkey, B. E., & Collins, S. (2009) · Endocrinology · doi:10.1210/en.2008-1642 · Cited by 163

No Evidence for a Basal, Retinoic, or Superoxide-induced Uncoupling Activity of the Uncoupling Protein 2 Present in Spleen or Lung Mitochondria

Couplan, E., del Mar Gonzalez-Barroso, M., Alves-Guerra, M. C., Ricquier, D., Goubern, M., & Bouillaud, F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202535200 · Cited by 161

UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

Bouillaud, F. (2009) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2009.01.003 · Cited by 146

The regulation and turnover of mitochondrial uncoupling proteins

Azzu, V., Jastroch, M., Divakaruni, A. S., & Brand, M. D. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.02.035 · Cited by 146

Upregulation of uncoupling proteins by oral administration of capsiate, a nonpungent capsaicin analog

Masuda, Y., Haramizu, S., Oki, K., Ohnuki, K., Watanabe, T., Yazawa, S., Kawada, T., Hashizume, S.-I., & Fushiki, T. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00828.2002 · Cited by 143

The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes

Jia, J. ‐., Zhang, X., Ge, C. ‐., & Jois, M. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00569.x · Cited by 137

Hypothesis: the mitochondrial NO(*) signaling pathway, and the transduction of nitrosative to oxidative cell signals: an alternative function for cytochrome c oxidase

Brookes, P., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00805-x · Cited by 137

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

Robson-Doucette, C. A., Sultan, S., Allister, E. M., Wikstrom, J. D., Koshkin, V., Bhattacharjee, A., Prentice, K. J., Sereda, S. B., Shirihai, O. S., & Wheeler, M. B. (2011) · Diabetes · doi:10.2337/db11-0132 · Cited by 136

Regulation of UCP1, UCP2, and UCP3 mRNA Expression in Brown Adipose Tissue, White Adipose Tissue, and Skeletal Muscle in Rats by Estrogen

Pedersen, S. B., Bruun, J. M., Kristensen, K., & Richelsen, B. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5763 · Cited by 134

Role of Innate Immune Response in Non-Alcoholic Fatty Liver Disease: Metabolic Complications and Therapeutic Tools

Meli, R., Mattace Raso, G., & Calignano, A. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00177 · Cited by 137

Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria

HARPER, J. A., STUART, J. A., JEKABSONS, M. B., ROUSSEL, D., BRINDLE, K. M., DICKINSON, K., JONES, R. B., & BRAND, M. D. (2002) · Biochemical Journal · doi:10.1042/bj3610049 · Cited by 87

The efficiency of cellular energy transduction and its implications for obesity

Harper, M.-E., Green, K., & Brand, M. D. (2008) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.28.061807.155357 · Cited by 121

Triiodothyronine‐mediated upregulation of UCP2 and UCP3 mRNA expression in human skeletal muscle without coordinated induction of mitochondrial respiratory chain genes

Barbe, P., Larrouy, D., Boulanger, C., Chevillotte, E., Viguerie, N., Thalamas, C., Oliva Trastoy, M., Roques, M., Vidal, H., & Langin, D. (2001) · The FASEB Journal · doi:10.1096/fj.00-0502fje · Cited by 118

The uncoupling protein 2 modulates the cytokine balance in innate immunity☆

ROUSSET, S., EMRE, Y., JOINLAMBERT, O., HURTAUD, C., RICQUIER, D., & CASSARDDOULCIER, A. (2006) · Cytokine · doi:10.1016/j.cyto.2006.07.012 · Cited by 114

The Genetics of Obesity Lessons for Polycystic Ovary Syndrome

LEGRO, R. S. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06230.x · Cited by 109

Homologues of the uncoupling protein from brown adipose tissue (UCP1): UCP2, UCP3, BMCP1 and UCP4

Bouillaud, F., Couplan, E., Pecqueur, C., & Ricquier, D. (2001) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00241-3 · Cited by 111

Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels

De Bilbao, F., Arsenijevic, D., Vallet, P., Hjelle, O. P., Ottersen, O. P., Bouras, C., Raffin, Y., Abou, K., Langhans, W., Collins, S., et al. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02432.x · Cited by 108

Effects of Adenoviral Overexpression of Uncoupling Protein-2 and -3 on Mitochondrial Respiration in Insulinoma Cells**This work was supported by V.A. Medical Research Funds and NIH Grants DK-25295 and HD-29569.

Hong, Y., Fink, B. D., Dillon, J. S., & Sivitz, W. I. (2001) · Endocrinology · doi:10.1210/endo.142.1.7889 · Cited by 107

Maternal Nutritional Programming of Fetal Adipose Tissue Development: Differential Effects on Messenger Ribonucleic Acid Abundance for Uncoupling Proteins and Peroxisome Proliferator-Activated and Prolactin Receptors

Bispham, J., Gardner, D. S., Gnanalingham, M. G., Stephenson, T., Symonds, M. E., & Budge, H. (2005) · Endocrinology · doi:10.1210/en.2005-0246 · Cited by 101

Physiological Levels of Mammalian Uncoupling Protein 2 Do Not Uncouple Yeast Mitochondria

Stuart, J. A., Harper, J. A., Brindle, K. M., Jekabsons, M. B., & Brand, M. D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011566200 · Cited by 99

Mitochondrial Uncoupling: Role of Uncoupling Protein Anion Carriers and Relationship to Thermogenesis and Weight Control “The Benefits of Losing Control”

Diehl, A. M., & Hoek, J. B. (1999) · Journal of Bioenergetics and Biomembranes · doi:10.1023/a:1005452624640 · Cited by 95

Decreased fatty acid synthesis due to mitochondrial uncoupling in adipose tissue

Rossmeisl, M., Syrový, I., Baumruk, F., Flachs, P., Janovska, P., & Kopecký, J. (2000) · The FASEB Journal · doi:10.1096/fj.99-0965com · Cited by 89

Human Uncoupling Protein‐3 and Obesity: An Update

Hesselink, M. K. C., Mensink, M., & Schrauwen, P. (2003) · Obesity Research · doi:10.1038/oby.2003.192 · Cited by 85

Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics

Yu, X. X., Barger, J. L., Boyer, B. B., Brand, M. D., Pan, G., & Adams, S. H. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.2.e433 · Cited by 81

Obesity exacerbates chemically induced neurodegeneration

Sriram, K., Benkovic, S. A., Miller, D. B., & O’Callaghan, J. P. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00306-8 · Cited by 78

Uncoupling Proteins: Role in Insulin Resistance and Insulin Insufficiency

B.Chan, C., & Harper, M.-E. (2006) · Current Diabetes Reviews · doi:10.2174/157339906777950660 · Cited by 71

First evidence and characterization of an uncoupling protein in fungi kingdom: CpUCP of Candida parapsilosis

Jarmuszkiewicz, W., Milani, G., Fortes, F., Schreiber, A. Z., Sluse, F. E., & Vercesi, A. E. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01138-8 · Cited by 67

Mitochondrial uncoupling proteins in mammals and plants

Borecký, J., Maia, I. G., & Arruda, P. (2001) · Bioscience Reports · doi:10.1023/a:1013604526175 · Cited by 63

Insights into brown adipose tissue evolution and function from non-model organisms

Jastroch, M., Oelkrug, R., & Keipert, S. (2018) · Journal of Experimental Biology · doi:10.1242/jeb.169425 · Cited by 55

Thyroid hormone and the energetic cost of keeping body temperature

Silva, J. E. (2005) · Bioscience Reports · doi:10.1007/s10540-005-2882-9 · Cited by 44

Low-protein diet induces, whereas high-protein diet reduces hepatic FGF21 production in mice, but glucose and not amino acids up-regulate FGF21 in cultured hepatocytes

Chalvon-Demersay, T., Even, P. C., Tomé, D., Chaumontet, C., Piedcoq, J., Gaudichon, C., & Azzout-Marniche, D. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.07.002 · Cited by 37

Reconstitution of novel mitochondrial uncoupling proteins UCP2 and UCP3

Žáčkova, M., & Ježek, P. (2002) · Bioscience Reports · doi:10.1023/a:1016009022186 · Cited by 25

Effect of Maternal Dexamethasone Treatment and Ambient Temperature on Prolactin Receptor Abundance in Brown Adipose and Hepatic Tissue in the Foetus and New‐born Lamb

Bispham, Heasman, Clarke, Ingleton, Stephenson, & Symonds (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00401.x · Cited by 24

Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release

Hirschberg Jensen, V., & Affourtit, C. (2015) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2015.03.008 · Cited by 9