Improved vectors and genome-wide libraries for CRISPR screening

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Items 101–199 of 199

1. Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
   Hogg, Simon J., Motorna, Olga, Cluse, Leonie A., Johanson, Timothy M., Coughlan, Hannah D., Raviram, Ramya, Myers, Robert M., Costacurta, Matteo, Todorovski, Izabela, Pijpers, Lizzy et al. · 2021 · Molecular Cell
2. Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
   Wroblewska, Aleksandra, Dhainaut, Maxime, Ben-Zvi, Benjamin, Rose, Samuel A., Park, Eun Sook, Amir, El-Ad David, Bektesevic, Anela, Baccarini, Alessia, Merad, Miriam, Rahman, Adeeb H. et al. · 2018 · Cell
3. An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER−/PR−/Her2− Human Breast Cancer Cells
   Novikov, Olga, Wang, Zhongyan, Stanford, Elizabeth A., Parks, Ashley J., Ramirez-Cardenas, Alejandra, Landesman, Esther, Laklouk, Israa, Sarita-Reyes, Carmen, Gusenleitner, Daniel, Li, Amy et al. · 2016 · Molecular Pharmacology
4. The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase
   Sanghvi, Viraj R., Leibold, Josef, Mina, Marco, Mohan, Prathibha, Berishaj, Marjan, Li, Zhuoning, Miele, Matthew M., Lailler, Nathalie, Zhao, Chunying, de Stanchina, Elisa et al. · 2019 · Cell
5. KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer
   Krall, Elsa B, Wang, Belinda, Munoz, Diana M, Ilic, Nina, Raghavan, Srivatsan, Niederst, Matthew J, Yu, Kristine, Ruddy, David A, Aguirre, Andrew J, Kim, Jong Wook et al. · 2017 · eLife
6. CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions
   Gasperini, Molly, Findlay, Gregory M., McKenna, Aaron, Milbank, Jennifer H., Lee, Choli, Zhang, Melissa D., Cusanovich, Darren A., Shendure, Jay · 2017 · The American Journal of Human Genetics
7. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
   Rusu, Victor, Hoch, Eitan, Mercader, Josep M., Tenen, Danielle E., Gymrek, Melissa, Hartigan, Christina R., DeRan, Michael, von Grotthuss, Marcin, Fontanillas, Pierre, Spooner, Alexandra et al. · 2017 · Cell
8. LDLRAD3 is a receptor for Venezuelan equine encephalitis virus
   Ma, Hongming, Kim, Arthur S., Kafai, Natasha M., Earnest, James T., Shah, Aadit P., Case, James Brett, Basore, Katherine, Gilliland, Theron C., Sun, Chengqun, Nelson, Christopher A. et al. · 2020 · Nature
9. VEGF regulates local inhibitory complement proteins in the eye and kidney
   Keir, Lindsay S., Firth, Rachel, Aponik, Lyndsey, Feitelberg, Daniel, Sakimoto, Susumu, Aguilar, Edith, Welsh, Gavin I., Richards, Anna, Usui, Yoshihiko, Satchell, Simon C. et al. · 2016 · Journal of Clinical Investigation
10. The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
    Kovalski, Joanna R., Bhaduri, Aparna, Zehnder, Ashley M., Neela, Poornima H., Che, Yonglu, Wozniak, Glenn G., Khavari, Paul A. · 2019 · Molecular Cell
11. Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing
    Ortinski, Pavel I., O’Donovan, Bernadette, Dong, Xiaoyu, Kantor, Boris · 2017 · Molecular Therapy - Methods & Clinical Development
12. AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity
    Di Micco, Antonia, Frera, Gianluca, Lugrin, Jérôme, Jamilloux, Yvan, Hsu, Erh-Ting, Tardivel, Aubry, De Gassart, Aude, Zaffalon, Léa, Bujisic, Bojan, Siegert, Stefanie et al. · 2016 · Proceedings of the National Academy of Sciences
13. Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication
    Ardeljan, Daniel, Steranka, Jared P., Liu, Chunhong, Li, Zhi, Taylor, Martin S., Payer, Lindsay M., Gorbounov, Mikhail, Sarnecki, Jacob S., Deshpande, Vikram, Hruban, Ralph H. et al. · 2020 · Nature Structural & Molecular Biology
14. Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells
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15. Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer
    McMillan, Elizabeth A., Ryu, Myung-Jeom, Diep, Caroline H., Mendiratta, Saurabh, Clemenceau, Jean R., Vaden, Rachel M., Kim, Ju-Hwa, Motoyaji, Takashi, Covington, Kyle R., Peyton, Michael et al. · 2018 · Cell
16. Interleukin-13 drives metabolic conditioning of muscle to endurance exercise
    Knudsen, Nelson H., Stanya, Kristopher J., Hyde, Alexander L., Chalom, Mayer M., Alexander, Ryan K., Liou, Yae-Huei, Starost, Kyle A., Gangl, Matthew R., Jacobi, David, Liu, Sihao et al. · 2020 · Science
17. KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides
    Ficarelli, Mattia, Wilson, Harry, Pedro Galão, Rui, Mazzon, Michela, Antzin-Anduetza, Irati, Marsh, Mark, Neil, Stuart JD, Swanson, Chad M · 2019 · eLife
18. Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling
    de Araujo, Mariana E. G., Naschberger, Andreas, Fürnrohr, Barbara G., Stasyk, Taras, Dunzendorfer-Matt, Theresia, Lechner, Stefan, Welti, Stefan, Kremser, Leopold, Shivalingaiah, Giridhar, Offterdinger, Martin et al. · 2017 · Science
19. Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression
    Hsu, Wen-Hao, LaBella, Kyle A., Lin, Yiyun, Xu, Ping, Lee, Rumi, Hsieh, Cheng-En, Yang, Lei, Zhou, Ashley, Blecher, Jonathan M., Wu, Chang-Jiun et al. · 2023 · Cancer Discovery
20. Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity
    Sievers, Quinlan L., Gasser, Jessica A., Cowley, Glenn S., Fischer, Eric S., Ebert, Benjamin L. · 2018 · Blood
21. BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells
    Mita, Paolo, Sun, Xiaoji, Fenyö, David, Kahler, David J., Li, Donghui, Agmon, Neta, Wudzinska, Aleksandra, Keegan, Sarah, Bader, Joel S., Yun, Chi et al. · 2020 · Nature Structural & Molecular Biology
22. Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    Shirasaki, Ryosuke, Matthews, Geoffrey M., Gandolfi, Sara, de Matos Simoes, Ricardo, Buckley, Dennis L., Raja Vora, Joseline, Sievers, Quinlan L., Brüggenthies, Johanna B., Dashevsky, Olga, Poarch, Haley et al. · 2021 · Cell Reports
23. Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression
    Kriegsman, Barry A, Vangala, Pranitha, Chen, Benjamin J, Meraner, Paul, Brass, Abraham L, Garber, Manuel, Rock, Kenneth L · 2019 · The Journal of Immunology
24. IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells
    Chen, Xing, Cai, Gang, Liu, Caini, Zhao, Junjie, Gu, Chunfang, Wu, Ling, Hamilton, Thomas A., Zhang, Cun-jin, Ko, Jennifer, Zhu, Liang et al. · 2019 · Journal of Experimental Medicine
25. A non-death function of the mitochondrial apoptosis apparatus in immunity
    Brokatzky, Dominik, Dörflinger, Benedikt, Haimovici, Aladin, Weber, Arnim, Kirschnek, Susanne, Vier, Juliane, Metz, Arlena, Henschel, Julia, Steinfeldt, Tobias, Gentle, Ian E et al. · 2019 · The EMBO Journal
26. MRTF potentiates TEAD‐YAP transcriptional activity causing metastasis
    Kim, Tackhoon, Hwang, Daehee, Lee, Dahye, Kim, Jeong‐Hwan, Kim, Seon‐Young, Lim, Dae‐Sik · 2017 · The EMBO Journal
27. Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence
    Franco-Barraza, Janusz, Francescone, Ralph, Luong, Tiffany, Shah, Neelima, Madhani, Raj, Cukierman, Gil, Dulaimi, Essel, Devarajan, Karthik, Egleston, Brian L, Nicolas, Emmanuelle et al. · 2017 · eLife
28. Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells
    Nagpal, Neha, Wang, Jianing, Zeng, Jing, Lo, Emily, Moon, Diane H., Luk, Kevin, Braun, Roman O., Burroughs, Lauri M., Keel, Sioban B., Reilly, Christopher et al. · 2020 · Cell Stem Cell
29. A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
    Sun, Hong, Huang, Yu, Mei, Shan, Xu, Fengwen, Liu, Xiaoman, Zhao, Fei, Yin, Lijuan, Zhang, Di, Wei, Liang, Wu, Chao et al. · 2021 · Cell Reports
30. Growth factor signaling to mTORC1 by amino acid–laden macropinosomes
    Yoshida, Sei, Pacitto, Regina, Yao, Yao, Inoki, Ken, Swanson, Joel A. · 2015 · Journal of Cell Biology
31. Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures
    Boonekamp, Kim E., Kretzschmar, Kai, Wiener, Dominique J., Asra, Priyanca, Derakhshan, Sepideh, Puschhof, Jens, López-Iglesias, Carmen, Peters, Peter J., Basak, Onur, Clevers, Hans · 2019 · Proceedings of the National Academy of Sciences
32. Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells
    Viswanatha, Raghuvir, Li, Zhongchi, Hu, Yanhui, Perrimon, Norbert · 2018 · eLife
33. Role for the IFT-A Complex in Selective Transport to the Primary Cilium
    Fu, Wenxiang, Wang, Lei, Kim, Sehyun, Li, Ji, Dynlacht, Brian David · 2016 · Cell Reports
34. Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM
    Song, Kyung-A, Niederst, Matthew J., Lochmann, Timothy L., Hata, Aaron N., Kitai, Hidenori, Ham, Jungoh, Floros, Konstantinos V., Hicks, Mark A., Hu, Haichuan, Mulvey, Hillary E. et al. · 2018 · Clinical Cancer Research
35. Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function
    Zhang, Yuanyue, Bailey, Jacob T., Xu, En, Singh, Kunal, Lavaert, Marieke, Link, Verena M., D’Souza, Shanti, Hafiz, Alex, Cao, Jian, Cao, Gaoyuan et al. · 2022 · Nature Immunology
36. Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
    Dieter, Sebastian M., Siegl, Christine, Codó, Paula L., Huerta, Mario, Ostermann-Parucha, Anna L., Schulz, Erik, Zowada, Martina K., Martin, Sylvia, Laaber, Karin, Nowrouzi, Ali et al. · 2021 · Cell Reports
37. Histone H3K4me1 and H3K27ac play roles in nucleosome eviction and eRNA transcription, respectively, at enhancers
    Kang, Yujin, Kim, Yea Woon, Kang, Jin, Kim, AeRi · 2021 · The FASEB Journal
38. ATG9A protects the plasma membrane from programmed and incidental permeabilization
    Claude-Taupin, Aurore, Jia, Jingyue, Bhujabal, Zambarlal, Garfa-Traoré, Meriem, Kumar, Suresh, da Silva, Gustavo Peixoto Duarte, Javed, Ruheena, Gu, Yuexi, Allers, Lee, Peters, Ryan et al. · 2021 · Nature Cell Biology
39. Molecular basis for substrate recruitment to the PRMT5 methylosome
    Mulvaney, Kathleen M., Blomquist, Christa, Acharya, Nischal, Li, Ruitong, Ranaghan, Matthew J., O’Keefe, Meghan, Rodriguez, Diego J., Young, Michael J., Kesar, Devishi, Pal, Debjani et al. · 2021 · Molecular Cell
40. A Landscape of Therapeutic Cooperativity in KRAS Mutant Cancers Reveals Principles for Controlling Tumor Evolution
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41. CGAS is a micronucleophagy receptor for the clearance of micronuclei
    Zhao, Mengmeng, Wang, Fei, Wu, Juehui, Cheng, Yuanna, Cao, Yajuan, Wu, Xiangyang, Ma, Mingtong, Tang, Fen, Liu, Zhi, Liu, Haipeng et al. · 2021 · Autophagy
42. A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity
    Liu, Jiye, Song, Tianyu, Zhou, Wenrong, Xing, Lijie, Wang, Su, Ho, Matthew, Peng, Zhengang, Tai, Yu-Tzu, Hideshima, Teru, Anderson, Kenneth C. et al. · 2019 · Leukemia
43. ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer
    Huang, Yun-Han, Hu, Jing, Chen, Fei, Lecomte, Nicolas, Basnet, Harihar, David, Charles J., Witkin, Matthew D., Allen, Peter J., Leach, Steven D., Hollmann, Travis J. et al. · 2020 · Cancer Discovery
44. Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells
    Mao, Pingsu, Liu, Jingfan, Zhang, Zepeng, Zhang, Hong, Liu, Haiying, Gao, Song, Rong, Yikang S., Zhao, Yong · 2016 · Nature Communications
45. Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq
    Wessels, Hans-Hermann, Méndez-Mancilla, Alejandro, Hao, Yuhan, Papalexi, Efthymia, Mauck, William M., Lu, Lu, Morris, John A., Mimitou, Eleni P., Smibert, Peter, Sanjana, Neville E. et al. · 2023 · Nature Methods
46. Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
    Kitajima, Shunsuke, Asahina, Hajime, Chen, Ting, Guo, Sujuan, Quiceno, Laura Gutierrez, Cavanaugh, Jillian D., Merlino, Ashley A., Tange, Shoichiro, Terai, Hideki, Kim, Jong Wook et al. · 2018 · Cancer Cell
47. Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of <i>ATRX</i> -Mutant Cancers to WEE1 Inhibition
    Liang, Junbo, Zhao, Hong, Diplas, Bill H., Liu, Song, Liu, Jianmei, Wang, Dingding, Lu, Yan, Zhu, Qing, Wu, Jiayu, Wang, Wenjia et al. · 2020 · Cancer Research
48. A genetic interaction analysis identifies cancer drivers that modify EGFR dependency
    Liao, Sida, Davoli, Teresa, Leng, Yumei, Li, Mamie Z., Xu, Qikai, Elledge, Stephen J. · 2017 · Genes &amp; Development
49. Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression
    Garstkiewicz, Martha, Strittmatter, Gerhard E., Grossi, Serena, Sand, Jennifer, Fenini, Gabriele, Werner, Sabine, French, Lars E., Beer, Hans‐Dietmar · 2017 · European Journal of Immunology
50. The Hippo pathway modulates resistance to BET proteins inhibitors in lung cancer cells
    Gobbi, Giulia, Donati, Benedetta, Do Valle, Italo Faria, Reggiani, Francesca, Torricelli, Federica, Remondini, Daniel, Castellani, Gastone, Ambrosetti, Davide Carlo, Ciarrocchi, Alessia, Sancisi, Valentina · 2019 · Oncogene
51. TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors
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52. Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer
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53. Lactation improves pancreatic β cell mass and function through serotonin production
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54. Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development
    Cheu, Jacinth Wing-Sum, Chiu, David Kung-Chun, Kwan, Kenneth Kin-Leung, Yang, Chunxue, Yuen, Vincent Wai-Hin, Goh, Chi Ching, Chui, Noreen Nog-Qin, Shen, Wei, Law, Cheuk-Ting, Li, Qidong et al. · 2023 · Science Advances
55. Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC
    Zeng, Hao, Castillo-Cabrera, Johnny, Manser, Mika, Lu, Bo, Yang, Zinger, Strande, Vaik, Begue, Damien, Zamponi, Raffaella, Qiu, Shumei, Sigoillot, Frederic et al. · 2019 · eLife
56. A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells
    Murakami, Kazuhiro, Terakado, Yumi, Saito, Kikue, Jomen, Yoshie, Takeda, Haruna, Oshima, Masanobu, Barker, Nick · 2021 · Proceedings of the National Academy of Sciences
57. Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification
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58. Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia
    Parajuli, Parash, Kumar, Santosh, Loumaye, Audrey, Singh, Purba, Eragamreddy, Sailaja, Nguyen, Thien Ly, Ozkan, Seval, Razzaque, Mohammed S., Prunier, Céline, Thissen, Jean-Paul et al. · 2018 · Developmental Cell
59. Cas9 protein delivery non-integrating lentiviral vectors for gene correction in sickle cell disease
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60. TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
    Carey, Kimberly L., Paulus, Geraldine L.C., Wang, Lingfei, Balce, Dale R., Luo, Jessica W., Bergman, Phil, Ferder, Ianina C., Kong, Lingjia, Renaud, Nicole, Singh, Shantanu et al. · 2020 · Cell Reports
61. Glutamine deprivation triggers NAGK-dependent hexosamine salvage
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62. Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms
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63. CIP2A interacts with TopBP1 and is selectively essential for DNA damage-induced basal-like breast cancer tumorigenesis
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64. Selective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cells
    Lee, Wookjae, Lee, Joon Ho, Jun, Soyeong, Lee, Ji Hyun, Bang, Duhee · 2018 · Scientific Reports
65. Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions
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66. Blackjack mutations improve the on-target activities of increased fidelity variants of SpCas9 with 5′ G-extended sgRNAs
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67. Genome-scale chemogenomic CRISPR screens in human cells using the TKOv3 library
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68. High-resolution characterization of gene function using single-cell CRISPR tiling screen
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69. Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting
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70. Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis
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71. Candidate-based screening via gene modulation in human neurons and astrocytes implicates<i>FERMT2</i>in A<b>β</b>and TAU proteostasis
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72. Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts
    Deb Roy, Abhijit, Yin, Taofei, Choudhary, Shilpa, Rodionov, Vladimir, Pilbeam, Carol C., Wu, Yi I. · 2017 · Nature Communications
73. Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors
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74. A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers
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75. Hepatitis C Virus Indirectly Disrupts DNA Damage-Induced p53 Responses by Activating Protein Kinase R
    Mitchell, Jonathan K., Midkiff, Bentley R., Israelow, Benjamin, Evans, Matthew J., Lanford, Robert E., Walker, Christopher M., Lemon, Stanley M., McGivern, David R. · 2017 · mBio
76. Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
    Amodio, Vito, Lamba, Simona, Chilà, Rosaria, Cattaneo, Chiara M., Mussolin, Benedetta, Corti, Giorgio, Rospo, Giuseppe, Berrino, Enrico, Tripodo, Claudio, Pisati, Federica et al. · 2023 · Cancer Cell
77. MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq
    Kluesner, Mitchell G., Tasakis, Rafail Nikolaos, Lerner, Taga, Arnold, Annette, Wüst, Sandra, Binder, Marco, Webber, Beau R., Moriarity, Branden S., Pecori, Riccardo · 2021 · Molecular Therapy — Nucleic Acids
78. SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling
    Sun, Dawei, Llora Batlle, Oriol, van den Ameele, Jelle, Thomas, John C, He, Peng, Lim, Kyungtae, Tang, Walfred, Xu, Chufan, Meyer, Kerstin B, Teichmann, Sarah A et al. · 2022 · The EMBO Journal
79. Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy
    Kleeman, Sam O., Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef J.R.A., Lee, Hassal, Chantzichristos, Dimitrios et al. · 2023 · Cell Genomics
80. The mitochondrial Cu+ transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro
    McCann, Cat, Quinteros, Michael, Adelugba, Ifeoluwa, Morgada, Marcos N., Castelblanco, Aida R., Davis, Emily J., Lanzirotti, Antonio, Hainer, Sarah J., Vila, Alejandro J., Navea, Juan G. et al. · 2022 · Frontiers in Molecular Biosciences
81. Inhibition of 4EBP phosphorylation mediates the cytotoxic effect of mechanistic target of rapamycin kinase inhibitors in aggressive B-cell lymphomas
    Bi, Chengfeng, Zhang, Xuan, Lu, Ting, Zhang, Xiaoyan, Wang, Xianhuo, Meng, Bin, Zhang, Huilai, Wang, Ping, Vose, Julie M., Chan, Wing C. et al. · 2017 · Haematologica
82. Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer
    Cheng, Derek K., Oni, Tobiloba E., Thalappillil, Jennifer S., Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V., Addison, Kenneth, Rivera, Keith D., Pappin, Darryl J. et al. · 2021 · Proceedings of the National Academy of Sciences
83. Genome-wide CRISPR screens reveal genetic mediators of cereblon modulator toxicity in primary effusion lymphoma
    Patil, Ajinkya, Manzano, Mark, Gottwein, Eva · 2019 · Blood Advances
84. Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer
    Jin, Yixin, Lorvik, Kristina Berg, Jin, Yang, Beck, Carole, Sike, Adam, Persiconi, Irene, Kvaløy, Emilie, Saatcioglu, Fahri, Dunn, Claire, Kyte, Jon Amund · 2022 · Molecular Therapy - Oncolytics
85. ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia
    Xiong, Yiwei, Li, Yanli, Cui, Xinxing, Zhang, Lifeng, Yang, Xiaodong, Liu, Hebin · 2022 · Cellular &amp; Molecular Immunology
86. The TMEM127 human tumor suppressor is a component of the mTORC1 lysosomal nutrient-sensing complex
    Deng, Yilun, Qin, Yuejuan, Srikantan, Subramanya, Luo, Anqi, Cheng, Zi-Ming, Flores, Shahida K, Vogel, Kris S, Wang, Exing, Dahia, Patricia L M · 2018 · Human Molecular Genetics
87. Rapid interrogation of cancer cell of origin through CRISPR editing
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