The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
The regulation of IL-10 production by immune cells
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Akira, S., & Takeda, K. (2004) · Nature reviews. Immunology · doi:10.1038/nri1391 · Cited by 8,312
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187
Interleukin-10 and the Interleukin-10 Receptor
Moore, K. W., de Waal Malefyt, R., Coffman, R. L., & O'Garra, A. (2001) · Annual Review of Immunology · doi:10.1146/annurev.immunol.19.1.683 · Cited by 6,737
Self-citationde Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., & de Vries, J. E. (1991) · The Journal of experimental medicine · doi:10.1084/jem.174.5.1209 · Cited by 3,762
IL-10 inhibits cytokine production by activated macrophages
Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M., & O’Garra, A. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.147.11.3815 · Cited by 2,888
Self-citationRecognition of microorganisms and activation of the immune response
Medzhitov, R. (2007) · Nature · doi:10.1038/nature06246 · Cited by 2,862
McGeachy, M. J., Bak-Jensen, K. S., Chen, Y., Tato, C. M., Blumenschein, W., McClanahan, T., & Cua, D. J. (2007) · Nature Immunology · doi:10.1038/ni1539 · Cited by 1,520
Bcl6 mediates the development of T follicular helper cells
Nurieva, R. I., Chung, Y., Martinez, G. J., Yang, X. O., Tanaka, S., Matskevitch, T. D., Wang, Y.-H., & Dong, C. (2009) · Science · doi:10.1126/science.1176676 · Cited by 1,506
Sellon, R. K., Tonkonogy, S., Schultz, M., Dieleman, L. A., Grenther, W., Balish, E., Rennick, D. M., & Sartor, R. B. (1998) · Infection and Immunity · doi:10.1128/iai.66.11.5224-5231.1998 · Cited by 1,483
Maynard, C. L., Harrington, L. E., Janowski, K. M., Oliver, J. R., Zindl, C. L., Rudensky, A. Y., & Weaver, C. T. (2007) · Nature Immunology · doi:10.1038/ni1504 · Cited by 599
Cited by
Protective and pathogenic functions of macrophage subsets
Murray, P. J., & Wynn, T. A. (2011) · Nature Reviews Immunology · doi:10.1038/nri3073 · Cited by 5,269
Macrophages in Tissue Repair, Regeneration, and Fibrosis
Wynn, T. A., & Vannella, K. M. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.015 · Cited by 4,481
Cytokines in inflammatory bowel disease
Neurath, M. F. (2014) · Nature Reviews Immunology · doi:10.1038/nri3661 · Cited by 2,706
Ruffell, B., Chang-Strachan, D., Chan, V., Rosenbusch, A., Ho, C. M. T., Pryer, N., Daniel, D., Hwang, E. S., Rugo, H. S., & Coussens, L. M. (2014) · Cancer Cell · doi:10.1016/j.ccell.2014.09.006 · Cited by 1,008
Chaudhry, A., Samstein, R. M., Treuting, P., Liang, Y., Pils, M. C., Heinrich, J.-M., Jack, R. S., Wunderlich, F. T., Brüning, J. C., Müller, W., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.03.018 · Cited by 980
The aryl hydrocarbon receptor: multitasking in the immune system
Stockinger, B., Meglio, P. D., Gialitakis, M., & Duarte, J. H. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120245 · Cited by 909
The role of the transcription factor CREB in immune function
Wen, A. Y., Sakamoto, K. M., & Miller, L. S. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001829 · Cited by 790
Promoting tissue regeneration by modulating the immune system
Julier, Z., Park, A. J., Briquez, P. S., & Martino, M. M. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.01.056 · Cited by 766
The spectrum of inflammatory responses
Medzhitov, R. (2021) · Science · doi:10.1126/science.abi5200 · Cited by 718
Immune modulation by mesenchymal stem cells
Jiang, W., & Xu, J. (2020) · Cell Proliferation · doi:10.1111/cpr.12712 · Cited by 650
Resolution of Inflammation: What Controls Its Onset?
Sugimoto, M. A., Sousa, L. P., Pinho, V., Perretti, M., & Teixeira, M. M. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00160 · Cited by 638
Childs, C. E., Calder, P. C., & Miles, E. A. (2019) · Nutrients · doi:10.3390/nu11081933 · Cited by 532
Apoptotic cell: linkage of inflammation and wound healing
Wu, Y.-S., & Chen, S.-N. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00001 · Cited by 500
Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis
Su, X., Gao, Y., & Yang, R. (2022) · Cells · doi:10.3390/cells11152296 · Cited by 424
B cells responses and cytokine production are regulated by their immune microenvironment
Vazquez, M. I., Catalan-Dibene, J., & Zlotnik, A. (2015) · Cytokine · doi:10.1016/j.cyto.2015.02.007 · Cited by 421
Heterogeneity of Human CD4 + T Cells Against Microbes
Sallusto, F. (2016) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032414-112056 · Cited by 336
Age-related changes in microRNA levels in serum
Hooten, N. N., Fitzpatrick, M., Wood, W. H., De, S., Ejiogu, N., Zhang, Y., Mattison, J. A., Becker, K. G., Zonderman, A. B., & Evans, M. K. (2013) · Aging · doi:10.18632/aging.100603 · Cited by 329
Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses
Farez, M. F., Mascanfroni, I. D., Méndez-Huergo, S. P., Yeste, A., Murugaiyan, G., Garo, L. P., Balbuena Aguirre, M. E., Patel, B., Ysrraelit, M. C., Zhu, C., et al. (2015) · Cell · doi:10.1016/j.cell.2015.08.025 · Cited by 318
Wang, Z., Chen, W.-H., Li, S.-X., He, Z.-M., Zhu, W.-L., Ji, Y.-B., Wang, Z., Zhu, X.-M., Yuan, K., Bao, Y.-P., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01113-1 · Cited by 307
Selected biomarkers of depression: what are the effects of cytokines and inflammation
Harsanyi, S., Kupcova, I., Danisovic, L., & Klein, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010578 · Cited by 299
Genomic views of STAT function in CD4+ T helper cell differentiation
O'Shea, J. J., Lahesmaa, R., Vahedi, G., Laurence, A., & Kanno, Y. (2011) · Nature Reviews Immunology · doi:10.1038/nri2958 · Cited by 295
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Delacher, M., Imbusch, C. D., Weichenhan, D., Breiling, A., Hotz-Wagenblatt, A., Träger, U., Hofer, A.-C., Kägebein, D., Wang, Q., Frauhammer, F., et al. (2017) · Nature Immunology · doi:10.1038/ni.3799 · Cited by 282
Hiles, S. A., Baker, A. L., de Malmanche, T., & Attia, J. (2012) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2012.06.001 · Cited by 274
Duffy, D., Rouilly, V., Libri, V., Hasan, M., Beitz, B., David, M., Urrutia, A., Bisiaux, A., LaBrie, S. T., Dubois, A., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.03.002 · Cited by 242
Cian, R., Drago, S., De Medina, F., & Martínez-Augustin, O. (2015) · Marine Drugs · doi:10.3390/md13085358 · Cited by 238
Yanguas‐Casás, N., Barreda‐Manso, M. A., Nieto‐Sampedro, M., & Romero‐Ramírez, L. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25742 · Cited by 223
Rossato, M., Curtale, G., Tamassia, N., Castellucci, M., Mori, L., Gasperini, S., Mariotti, B., De Luca, M., Mirolo, M., Cassatella, M. A., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209100109 · Cited by 215
Kwon, H.-K., Kim, G.-C., Kim, Y., Hwang, W., Jash, A., Sahoo, A., Kim, J.-E., Nam, J. H., & Im, S.-H. (2013) · Clinical Immunology · doi:10.1016/j.clim.2013.01.001 · Cited by 212
Control of inflammation by integration of environmental cues by regulatory T cells
Chaudhry, A., & Rudensky, A. Y. (2013) · Journal of Clinical Investigation · doi:10.1172/jci57175 · Cited by 183
Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways
Murray, P. J., & Smale, S. T. (2012) · Nature Immunology · doi:10.1038/ni.2391 · Cited by 170
Mishima, Y., Oka, A., Liu, B., Herzog, J. W., Eun, C. S., Fan, T.-J., Bulik-Sullivan, E., Carroll, I. M., Hansen, J. J., Chen, L., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci93820 · Cited by 166
Coudriet, G. M., He, J., Trucco, M., Mars, W. M., & Piganelli, J. D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015384 · Cited by 155
Cheng, F., Lienlaf, M., Perez-Villarroel, P., Wang, H.-W., Lee, C., Woan, K., Woods, D., Knox, T., Bergman, J., Pinilla-Ibarz, J., et al. (2014) · Molecular Immunology · doi:10.1016/j.molimm.2014.02.019 · Cited by 140
Acne, Microbiome, and Probiotics: The Gut–Skin Axis
Sánchez-Pellicer, P., Navarro-Moratalla, L., Núñez-Delegido, E., Ruzafa-Costas, B., Agüera-Santos, J., & Navarro-López, V. (2022) · Microorganisms · doi:10.3390/microorganisms10071303 · Cited by 137
miR-27a regulates inflammatory response of macrophages by targeting IL-10
Xie, N., Cui, H., Banerjee, S., Tan, Z., Salomao, R., Fu, M., Abraham, E., Thannickal, V. J., & Liu, G. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400203 · Cited by 128
Aschenbrenner, D., Quaranta, M., Banerjee, S., Ilott, N., Jansen, J., Steere, B., Chen, Y.-H., Ho, S., Cox, K., Arancibia-Cárcamo, C. V., et al. (2021) · Gut · doi:10.1136/gutjnl-2020-321731 · Cited by 123
Gravel, M., Béland, L.-C., Soucy, G., Abdelhamid, E., Rahimian, R., Gravel, C., & Kriz, J. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.0854-15.2016 · Cited by 117
Molecular composition of the alveolar lining fluid in the aging lung
Moliva, J. I., Rajaram, M. V. S., Sidiki, S., Sasindran, S. J., Guirado, E., Pan, X. J., Wang, S.-H., Ross, P., Lafuse, W. P., Schlesinger, L. S., et al. (2014) · AGE · doi:10.1007/s11357-014-9633-4 · Cited by 114
Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages
Wong, C.-O., Gregory, S., Hu, H., Chao, Y., Sepúlveda, V. E., He, Y., Li-Kroeger, D., Goldman, W. E., Bellen, H. J., & Venkatachalam, K. (2017) · Cell Host & Microbe · doi:10.1016/j.chom.2017.05.002 · Cited by 114
Cheng, F., Lienlaf, M., Wang, H.-W., Perez-Villarroel, P., Lee, C., Woan, K., Rock-Klotz, J., Sahakian, E., Woods, D., Pinilla-Ibarz, J., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302778 · Cited by 106
Biomarkers of post-covid depression
Lorkiewicz, P., & Waszkiewicz, N. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10184142 · Cited by 102
Ziegler, T., Rausch, S., Steinfelder, S., Klotz, C., Hepworth, M. R., Kühl, A. A., Burda, P.-C., Lucius, R., & Hartmann, S. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1401217 · Cited by 85
Webster, S. J., Van Eldik, L. J., Watterson, D. M., & Bachstetter, A. D. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.0291-15.2015 · Cited by 80
Cytokine response of human mononuclear cells induced by intestinal Clostridium species
Tuovinen, E., Keto, J., Nikkilä, J., Mättö, J., & Lähteenmäki, K. (2013) · Anaerobe · doi:10.1016/j.anaerobe.2012.11.002 · Cited by 75
Hoffman, B. E., Martino, A. T., Sack, B. K., Cao, O., Liao, G., Terhorst, C., & Herzog, R. W. (2011) · Molecular Therapy · doi:10.1038/mt.2011.33 · Cited by 72
Lin, L., Hou, J., Ma, F., Wang, P., Liu, X., Li, N., Wang, J., Wang, Q., & Cao, X. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203450 · Cited by 73
Hansen, I. S., Hoepel, W., Zaat, S. A. J., Baeten, D. L. P., & den Dunnen, J. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700883 · Cited by 69
Park, J.-S., Joe, I., Rhee, P. D., Jeong, C.-S., & Jeong, G. (2017) · Journal of Microbiology · doi:10.1007/s12275-017-6447-y · Cited by 65
Interleukin-10 deficiency exacerbates inflammation-induced tau pathology
Weston, L. L., Jiang, S., Chisholm, D., Jantzie, L. L., & Bhaskar, K. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02211-1 · Cited by 69
Altered Chemokine Levels in the Cerebrospinal Fluid and Plasma of Suicide Attempters
Janelidze, S., Ventorp, F., Erhardt, S., Hansson, O., Minthon, L., Flax, J., Samuelsson, M., Traskman-Bendz, L., & Brundin, L. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.09.010 · Cited by 69
Lauté-Caly, D. L., Raftis, E. J., Cowie, P., Hennessy, E., Holt, A., Panzica, D. A., Sparre, C., Minter, B., Stroobach, E., & Mulder, I. E. (2019) · Scientific Reports · doi:10.1038/s41598-018-36926-8 · Cited by 67
Bjurstrom, M. F., Giron, S. E., & Griffis, C. A. (2016) · Pain Practice · doi:10.1111/papr.12252 · Cited by 62
Adipose tissue insulin action and IL-6 signaling after exercise in obese mice
MACPHERSON, R. E. K., HUBER, J. S., FRENDO-CUMBO, S., SIMPSON, J. A., & WRIGHT, D. C. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000660 · Cited by 62
Jang, S. W., Cho, M. K., Park, M. K., Kang, S. A., Na, B.-K., Ahn, S. C., Kim, D.-H., & Yu, H. S. (2011) · The Korean Journal of Parasitology · doi:10.3347/kjp.2011.49.3.245 · Cited by 59
Interleukin-10 Level Is Associated with Post-Stroke Depression in Acute Ischaemic Stroke Patients
Chi, C.-H., Huang, Y.-Y., Ye, S.-Z., Shao, M.-M., Jiang, M.-X., Yang, M.-Y., Wu, Q., Shao, B., & Li, X.-M. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.06.037 · Cited by 50
Liu, J., Yu, Q., Wu, W., Huang, X., Broering, R., Werner, M., Roggendorf, M., Yang, D., & Lu, M. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1700540 · Cited by 50
The role of the gut microbiome in colorectal cancer: Where are we? Where are we going?
Wieczorska, K., Stolarek, M., & Stec, R. (2020) · Clinical Colorectal Cancer · doi:10.1016/j.clcc.2019.07.006 · Cited by 50
Selective Encapsulation of Therapeutic mRNA in Engineered Extracellular Vesicles by DNA Aptamer
Zhang, S., Dong, Y., Wang, Y., Sun, W., Wei, M., Yuan, L., & Yang, G. (2021) · Nano Letters · doi:10.1021/acs.nanolett.1c01817 · Cited by 50
Okamura, T., Yamamoto, K., & Fujio, K. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00340 · Cited by 41
Bellmann-Weiler, R., Schroll, A., Engl, S., Nairz, M., Talasz, H., Seifert, M., & Weiss, G. (2013) · Immunobiology · doi:10.1016/j.imbio.2012.11.004 · Cited by 43
Tausendschön, M., Rehli, M., Dehne, N., Schmidl, C., Döring, C., Hansmann, M.-L., & Brüne, B. (2015) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.10.006 · Cited by 43
Chou, W. K., Park, J., Carey, J. B., McIntyre, D. R., & Berghman, L. R. (2017) · Frontiers in Veterinary Science · doi:10.3389/fvets.2017.00037 · Cited by 36
Verstraeten, B. S. E., McCreary, J. K., Weyers, S., Metz, G. A. S., & Olson, D. M. (2019) · Biology of Reproduction · doi:10.1093/biolre/ioy166 · Cited by 28
Gonçalves, N. P., Teixeira-Coelho, M., & Saraiva, M. J. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.04.030 · Cited by 27
Self-citationCrafts, T. D., Hunsberger, E. B., Jensen, A. R., Rescorla, F. J., Yoder, M. C., & Markel, T. A. (2015) · Journal of Surgical Research · doi:10.1016/j.jss.2015.06.031 · Cited by 23
Bosschaerts, T., Morias, Y., Stijlemans, B., Hérin, M., Porta, C., Sica, A., Mantovani, A., De Baetselier, P., & Beschin, A. (2011) · European Journal of Immunology · doi:10.1002/eji.201041307 · Cited by 23
Vijapur, S. M., Yang, Z., Barton, D. J., Vaughan, L., Awan, N., Kumar, R. G., Oh, B.-M., Berga, S. L., Wang, K. K., & Wagner, A. K. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2019.6780 · Cited by 20
Mizobuchi, H. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1110583 · Cited by 11
The role of gender and labour status in immunosenescence of 65+ Polish population
Dudkowska, M., Janiszewska, D., Karpa, A., Broczek, K., Dabrowski, M., & Sikora, E. (2017) · Biogerontology · doi:10.1007/s10522-017-9702-z · Cited by 11
“IL10, in contrast to IL8, is an anti-inflammatory cytokine (Saraiva and O’Garra 2010) and it was shown to increase in elderly women, but not men (Ostan et al. 2016).”
BackgroundHuman recombinant IL-10 reduces xenogenic cytotoxicity via macrophage M2 polarization
Kim, Y. K., Kim, S. E., Chang Park, H., Hwang, J. H., & Lee, H. T. (2020) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2020.100857 · Cited by 8
Kiolbasa, M., Kotlarz, A., Kaminiów, K., & Pastuszczak, M. (2025) · International Journal of STD & AIDS · doi:10.1177/09564624241303816 · Cited by 2
Metadata
- Authors
- Saraiva, M., & O'Garra, A.
- Venue
- Nature Reviews Immunology
- Published
- 2010-02-15
- Volume
- 10
- Issue
- 3
- Pages
- 170-181
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2106684817
- Cited by
- 3,164
- References
- 18
- FWCI
- 15.01
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.