The DOI matches its Crossref record.
Species Differences in Central Oxytocin Receptor Gene Expression: Comparative Analysis of Promoter Sequences
Abstract
The distribution of oxytocin binding sites in the brain is highly variable among mammals. Using two species of microtine rodents (voles) with strikingly different patterns of oxytocin binding sites in the brain, we demonstrate that these differences are due to differences in region specific gene expression and not post-translational processing. The distribution of oxytocin receptor mRNA closely resembles the distribution of oxytocin receptor binding sites in both species. Analysis of the 5' flanking region of the oxytocin receptor gene from both species reveals few differences in potential regulatory elements which could explain the differences in gene expression. These data suggest that species differences in oxytocin receptor binding are due to species differences in: i) distant DNA sequences further upstream or downstream which may influence expression; ii) the distribution of regulatory proteins such as transcription factors in the brain or iii) epigenetic factors, such as prenatal and perinatal environment which may affect gene expression in the adult.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The sequence containing NT213739 overlapped peaks of DNase hypersensitivity and CTCF binding within the large intron, a region proposed to contain cis-REs in humans (20, 61, 62).”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [62]
In the citing paper
“and accumulates rare SNPs in cases of ASD (62).”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [62]
In the citing paper
“The amygdala, which possesses an unusually high density of OT receptors (Francis et al., 2000; Insel and Shapiro, 1992; Young et al., 1996), may be a key site through which OT influences social behavior.”
From Oxytocin and social cognition in rhesus macaques: Implications for understanding and treating human psychopathology (2014) · cites this paper as Young et al., 1996
In the citing paper
“Compared to montane voles, OT receptors in prairie voles are densely distributed in prelimbic areas, including a region analogous to the primate anterior cingulate gyrus, the nucleus accumbens, the bed nucleus of stria terminalis, and the lateral amygdala (Insel and Shapiro, 1992; Young et al., 1996).”
From Oxytocin and social cognition in rhesus macaques: Implications for understanding and treating human psychopathology (2014) · cites this paper as Young et al., 1996
Citations
Cites
Still being checked.
Cited by
Sorted by citations
Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425
The neurobiology of attachment
Insel, T. R., & Young, L. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35053579 · Cited by 1,173
Self-citationOxytocin: The Great Facilitator of Life
Lee, H.-J., Macbeth, A. H., Pagani, J., & Young, W. S. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.001 · Cited by 1,037
The oxytocin receptor: from intracellular signaling to behavior
Jurek, B., & Neumann, I. D. (2018) · Physiological Reviews · doi:10.1152/physrev.00031.2017 · Cited by 999
García‐Segura, L. M., Azcoitia, Í., & DonCarlos, L. L. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00025-3 · Cited by 945
Neuropeptidergic regulation of affiliative behavior and social bonding in animals
Lim, M. M., & Young, L. J. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.06.028 · Cited by 624
Self-citationHOW THE BRAIN PROCESSES SOCIAL INFORMATION: Searching for the Social Brain
Insel, T. R., & Fernald, R. D. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144148 · Cited by 556
Self-citationPositive Association of the Oxytocin Receptor Gene (OXTR) with Autism in the Chinese Han Population
Wu, S., Jia, M., Ruan, Y., Liu, J., Guo, Y., Mei, S., Gong, X., Zhang, Y., Yang, X., & Zhang, D. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.013 · Cited by 565
Bielsky, I. F., Hu, S.-B., Szegda, K. L., Westphal, H., & Young, L. J. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300360 · Cited by 531
Self-citationCellular Mechanisms of Social Attachment
Young, L. J., Lim, M. M., Gingrich, B., & Insel, T. R. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1691 · Cited by 523
Self-citationIs social attachment an addictive disorder?
Insel, T. R. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00148-3 · Cited by 430
Self-citationLukas, M., Toth, I., Reber, S. O., Slattery, D. A., Veenema, A. H., & Neumann, I. D. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.95 · Cited by 403
The neurobiology of pair bonding: Insights from a socially monogamous rodent
Young, K. A., Gobrogge, K. L., Liu, Y., & Wang, Z. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.07.006 · Cited by 389
Self-citationRoss, H. E., Freeman, S. M., Spiegel, L. L., Ren, X., Terwilliger, E. F., & Young, L. J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5039-08.2009 · Cited by 322
Self-citationOxytocin, vasopressin and pair bonding: implications for autism
Hammock, E. A. D., & Young, L. J. (2006) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2006.1939 · Cited by 296
Self-citationLiu, Y., Curtis, J. T., & Wang, Z. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.4.910 · Cited by 282
Self-citationNeuroendocrine bases of monogamy
Young, L. J., Wang, Z., & Insel, T. R. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01167-3 · Cited by 265
Self-citationAhern, T. H. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.017.2009 · Cited by 239
Oxytocin, vasopressin, and autism: Is there a connection?
Insel, T. R., O’Brien, D. J., & Leckman, J. F. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00142-5 · Cited by 226
Self-citationOxytocin and vasopressin: powerful regulators of social behavior
Caldwell, H. K. (2017) · The Neuroscientist · doi:10.1177/1073858417708284 · Cited by 216
Young, L. J., Winslow, J. T., Nilsen, R., & Insel, T. R. (1997) · Behavioral Neuroscience · doi:10.1037/0735-7044.111.3.599 · Cited by 196
Self-citationVariation in the Oxytocin Receptor Gene Is Associated with Pair-Bonding and Social Behavior
Walum, H., Lichtenstein, P., Neiderhiser, J. M., Reiss, D., Ganiban, J. M., Spotts, E. L., Pedersen, N. L., Anckarsäter, H., Larsson, H., & Westberg, L. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.09.002 · Cited by 211
Lukas, M., Toth, I., Veenema, A. H., & Neumann, I. D. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.09.018 · Cited by 211
Oxytocin and Vasopressin Receptors and Species-Typical Social Behaviors
Young, L. J. (1999) · Hormones and Behavior · doi:10.1006/hbeh.1999.1548 · Cited by 211
Self-citationKing, L. B., Walum, H., Inoue, K., Eyrich, N. W., & Young, L. J. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.12.008 · Cited by 191
“Comparisons of 1500 bp of 50 flanking regions from the Oxtr gene reveal only a few SNPs and 99% homology between the species (62).”
Self-citationLukas, M., Bredewold, R., Neumann, I. D., & Veenema, A. H. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.06.020 · Cited by 183
Histone deacetylase inhibitors facilitate partner preference formation in female prairie voles
Wang, H., Duclot, F., Liu, Y., Wang, Z., & Kabbaj, M. (2013) · Nature Neuroscience · doi:10.1038/nn.3420 · Cited by 173
Self-citationOxytocin, Vasopressin, and the Neuroendocrine Basis of Pair Bond Formation
Insel, T. R., Winslow, J. T., Wang, Z., & Young, L. J. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4871-3_28 · Cited by 170
Self-citationYoung, K. A., Liu, Y., & Wang, Z. (2008) · Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology · doi:10.1016/j.cbpc.2008.02.004 · Cited by 163
Self-citationLim, M. M., Murphy, A. Z., & Young, L. J. (2004) · Journal of Comparative Neurology · doi:10.1002/cne.10973 · Cited by 163
Self-citationRed fox genome assembly identifies genomic regions associated with tame and aggressive behaviours
Kukekova, A. V., Johnson, J. L., Xiang, X., Feng, S., Liu, S., Rando, H. M., Kharlamova, A. V., Herbeck, Y., Serdyukova, N. A., Xiong, Z., et al. (2018) · Nature Ecology & Evolution · doi:10.1038/s41559-018-0611-6 · Cited by 145
Developmental experiences and the oxytocin receptor system
Bales, K. L., & Perkeybile, A. M. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.013 · Cited by 142
Oxytocin and experimental therapeutics in autism spectrum disorders
BARTZ, J., & HOLLANDER, E. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00435-4 · Cited by 139
Wang, Z., Liu, Y., Young, L. J., & Insel, T. R. (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00435.x · Cited by 134
Self-citationOxytocin, vasopressin, and the motivational forces that drive social behaviors
Caldwell, H. K., & Albers, H. E. (2015) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2015_390 · Cited by 129
Central oxytocin and reproductive behaviours
Insel, T. R. (1997) · Reviews of Reproduction · doi:10.1530/ror.0.0020028 · Cited by 129
Self-citationThe Neurobiology of Social Affiliation and Pair Bonding
Carter, C. S., & Keverne, E. B. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00004-8 · Cited by 130
Neurochemical regulation of pair bonding in male prairie voles
Wang, Z., & Aragona, B. J. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.08.024 · Cited by 128
Self-citationToward a Neurobiology of Attachment
Insel, T. R. (2000) · Review of General Psychology · doi:10.1037/1089-2680.4.2.176 · Cited by 122
Self-citationHammock, E. A. D. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00195 · Cited by 115
The Neurobiological Context of Autism
Keller, F., & Persico, A. M. (2003) · Molecular Neurobiology · doi:10.1385/mn:28:1:1 · Cited by 115
Aragona, B. J., & Wang, Z. (2004) · ILAR Journal · doi:10.1093/ilar.45.1.35 · Cited by 113
Self-citationLENG, G., ONAKA, T., CAQUINEAU, C., SABATIER, N., TOBIN, V, & TAKAYANAGI, Y. (2008) · Progress in brain research · doi:10.1016/s0079-6123(08)00413-5 · Cited by 112
Plasticity and constraints on social evolution in African mole-rats: ultimate and proximate factors
Faulkes, C. G., & Bennett, N. C. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0347 · Cited by 112
The Neurobiology of Social Affiliation and Pair Bonding
Carter, C. S., & Keverne, E. B. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50006-8 · Cited by 114
Gene targeting approaches to neuroendocrinology: oxytocin, maternal behavior, and affiliation
Young, L. J., Winslow, J. T., Wang, Z., Gingrich, B., Guo, Q., Matzuk, M. M., & Insel, T. R. (1997) · Hormones and Behavior · doi:10.1006/hbeh.1997.1377 · Cited by 105
Self-citationSerotonin and neuropeptides in affiliative behaviors
Insel, T. R., & Winslow, J. T. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00094-8 · Cited by 105
Self-citationMolecular regulation of the oxytocin receptor in peripheral organs
Kimura, T., Saji, F., Nishimori, K., Ogita, K., Nakamura, H., Koyama, M., & Murata, Y. (2003) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0300109 · Cited by 103
Intranasal oxytocin effects on social cognition: A critique
Evans, S. L., Dal Monte, O., Noble, P., & Averbeck, B. B. (2014) · Brain Research · doi:10.1016/j.brainres.2013.11.008 · Cited by 97
Kalamatianos, T., Faulkes, C. G., Oosthuizen, M. K., Poorun, R., Bennett, N. C., & Coen, C. W. (2010) · Journal of Comparative Neurology · doi:10.1002/cne.22302 · Cited by 92
Arborelius, L., Hawks, B. W., Owens, M. J., Plotsky, P. M., & Nemeroff, C. B. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1883-x · Cited by 89
The role of sex steroids in the oxytocin hormone system
Ivell, R., & Walther, N. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00025-8 · Cited by 86
Oxytocin receptor dynamics in the brain across development and species
Vaidyanathan, R., & Hammock, E. A. D. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22403 · Cited by 86
Tsapelas, I., Fisher, H. E., & Aron, A. P. (2010) · doi:10.4324/9780203874370-12 · Cited by 76
Loth, M. K., & Donaldson, Z. R. (2020) · Endocrinology · doi:10.1210/endocr/bqaa223 · Cited by 80
Curtis, J. T., Liu, Y., Aragona, B. J., & Wang, Z. (2006) · Brain Research · doi:10.1016/j.brainres.2006.07.126 · Cited by 74
Self-citationOlazábal, D. E., & Alsina‐Llanes, M. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.04.006 · Cited by 72
Chang, S. W. C., & Platt, M. L. (2014) · Brain Research · doi:10.1016/j.brainres.2013.11.006 · Cited by 71
Vasudevan, N., Davidkova, G., Zhu, Y., Koibuchi, N., Chin, W. W., & Pfaff, D. W. (2001) · Neuroendocrinology · doi:10.1159/000054698 · Cited by 65
Caldwell, H. K. (2012) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4614-1704-0_12 · Cited by 58
Wang, Z., & Young, L. J. (1997) · Developmental Brain Research · doi:10.1016/s0165-3806(97)00138-7 · Cited by 54
Self-citationA Neuroscientist’s Guide to the Vole
Kenkel, W. M., Gustison, M. L., & Beery, A. K. (2021) · Current Protocols · doi:10.1002/cpz1.175 · Cited by 52
The interplay of oxytocin and sex hormones
Quintana, D. S., Glaser, B. D., Kang, H., Kildal, E. S.-M., Audunsdottir, K., Sartorius, A. M., & Barth, C. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105765 · Cited by 54
Neuropeptide Regulation of Social Attachment: The Prairie Vole Model
Tabbaa, M., Paedae, B., Liu, Y., & Wang, Z. (2016) · Comprehensive physiology · doi:10.1002/cphy.c150055 · Cited by 54
Self-citationInoue, K., Ford, C. L., Horie, K., & Young, L. J. (2022) · Journal of Comparative Neurology · doi:10.1002/cne.25382 · Cited by 45
Self-citationOphir, A. G., Zheng, D.-J., Eans, S. O., & Phelps, S. M. (2009) · Behavioral Neuroscience · doi:10.1037/a0016663 · Cited by 46
McCarroll, S. A., Li, H., & Bargmann, C. I. (2005) · Current Biology · doi:10.1016/j.cub.2005.02.023 · Cited by 45
The Septal Region and Social Behavior
Sheehan, T. P., & Numan, M. (2000) · Springer eBooks · doi:10.1007/978-1-4612-1302-4_8 · Cited by 46
CD38 regulates oxytocin secretion and complex social behavior
Bartz, J. A., & McInnes, L. A. (2007) · BioEssays · doi:10.1002/bies.20623 · Cited by 39
Oxytocin And Individual Variation in Parental Care in Prairie Voles
Olazábal, D. E., & Young, L. J. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374285-8.00021-4 · Cited by 35
Self-citationMelanin‐concentrating hormone peptidergic system: Comparative morphology between muroid species
Diniz, G. B., Battagello, D. S., Cherubini, P. M., Reyes-Mendoza, J., Luna‐Illades, C., Klein, M., Motta‐Teixeira, L. C., Sita, L. V., Miranda‐Anaya, M., Morales, T., et al. (2019) · The Journal of Comparative Neurology · doi:10.1002/cne.24723 · Cited by 29
Investigation of an F-18 oxytocin receptor selective ligand via PET imaging
Smith, A. L., Freeman, S. M., Voll, R. J., Young, L. J., & Goodman, M. M. (2013) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2013.07.045 · Cited by 28
Self-citationPreuss, T. M. (2006) · Journal of Biomedical Discovery and Collaboration · doi:10.1186/1747-5333-1-17 · Cited by 26
Evolutionary diversity as a catalyst for biological discovery
JOHNSON, Z. V., & YOUNG, L. J. (2018) · Integrative Zoology · doi:10.1111/1749-4877.12339 · Cited by 25
Self-citationNeural mechanisms of reproduction in females as a predisposing factor for drug addiction
Hedges, V. L., Staffend, N. A., & Meisel, R. L. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.02.003 · Cited by 27
Kimura, T., & Ivell, R. (1999) · Results and problems in cell differentiation · doi:10.1007/978-3-540-49421-8_7 · Cited by 22
YOUNG, L. J., WAYMIRE, K. G., NILSEN, R., MACGREGOR, G. R., WANG, Z., & INSEL, T. R. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51955.x · Cited by 20
Self-citationOxytocin, vasopressin and their interplay with gonadal steroids
Dhakar, M. B., Stevenson, E. L., & Caldwell, H. K. (2013) · Oxytocin, Vasopressin and Related Peptides in the Regulation of Behavior · doi:10.1017/cbo9781139017855.003 · Cited by 20
An evaluation of what the mouse knockout experiments are telling us about mammalian behaviour
Keverne, E. B. (1997) · BioEssays · doi:10.1002/bies.950191208 · Cited by 19
Regulation of the human oxytocin receptor in the uterus: a molecular approach
Kimura, T. (1998) · Human Reproduction Update · doi:10.1093/humupd/4.5.615 · Cited by 18
BAC-Based Sequencing of Behaviorally-Relevant Genes in the Prairie Vole
McGraw, L. A., Davis, J. K., Thomas, P. J., Program, N. C. S., Young, L. J., & Thomas, J. W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029345 · Cited by 15
Self-citationThe Prairie Vole Model of Pair-Bonding and Its Sensitivity to Addictive Substances
Potretzke, S., & Ryabinin, A. E. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02477 · Cited by 20
Partner separation rescues pair bond-induced decreases in hypothalamic oxytocin neural densities
Fricker, B. A., Roshko, V. C., Jiang, J., & Kelly, A. M. (2023) · Scientific Reports · doi:10.1038/s41598-023-32076-8 · Cited by 15
The Neurobiology of Social Affiliation and Pair Bonding
Carter, C. S., & Keverne, E. B. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00004-3 · Cited by 14
Genetic ancestry predicts male-female affiliation in a natural baboon hybrid zone
Fogel, A. S., McLean, E. M., Gordon, J. B., Archie, E. A., Tung, J., & Alberts, S. C. (2020) · Animal Behaviour · doi:10.1016/j.anbehav.2021.07.009 · Cited by 9
The neural and genetic correlates of satisfying sexual activity in heterosexual pair‐bonds
Acevedo, B. P., Poulin, M. J., Geher, G., Grafton, S. T., & Brown, L. L. (2019) · Brain and Behavior · doi:10.1002/brb3.1289 · Cited by 11
Zingg, H. H. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50059-7 · Cited by 6
Kelberman, M. A., Winther, K. E., Medvedeva, Y. M., & Donaldson, Z. R. (2024) · Hormones and Behavior · doi:10.1016/j.yhbeh.2024.105647 · Cited by 4
Neuroendocrinology, Neurochemistry, and Molecular Neurobiology of Affiliative Behavior
Hammock, E. A. D., & Young, L. J. (2006) · Springer eBooks · doi:10.1007/978-0-387-30405-2_6 · Cited by 4
Self-citationBeyond lactation: Central oxytocin in maternal mental health and disease
Maier, E., Lan, W., Schimmer, S., Ishiyama, S., & Grinevich, V. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106697 · Cited by 1
The Behavioral Genetics of Human Pair Bonding
Walum, H., & Westberg, L. (2011) · Wiley eBooks · doi:10.1002/9781118101803.ch2 · Cited by 1
Vogel, H. G. (2007) · Springer eBooks · doi:10.1007/978-3-540-70995-4_15 · Cited by 1
Effects of central neuropeptides on social preference and social recognition in male rats
Lukas, M. (2011) · University of Regensburg Publication Server (University of Regensburg) · doi:10.5283/epub.22540
Genetic and hormonal influences on affiliative behavior in humans
Walum, H. (2012) · Figshare
Sandow, J. (2015) · Springer eBooks · doi:10.1007/978-3-319-05392-9_82
Young, L. J., & Zingg, H. H. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00056-0
Self-citationPROGRAMMING GENES IN BRAIN AND PROBLEM OF SOCIAL BEHAVIOR ОF MAN
Fuks, B. B. (2013) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2013-2-275-283
Vogel, H. G., Vogel, W. H., Schölkens, B. A., Sandow, J., Müller, G. A., & Vogel, W. F. (2002) · Springer eBooks · doi:10.1007/3-540-29837-1_15
Sweatt, J. D., & Day, J. J. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718018322.793478215
Metadata
- Authors
- Young, L. J., Huot, B., Nilsen, R., Wang, Z., & Insel, T. R.
- Affiliations
- Emory University (US)
- Corresponding author
- Young, Larry J.
- Venue
- Journal of Neuroendocrinology
- Publisher
- Wiley
- Published
- 1996-10
- Volume
- 8
- Issue
- 10
- Pages
- 777-783
- ISSN
- 0953-8194 (ISSN-L)
- 1365-2826
- OpenAlex
- W2047692024
- Cited by
- 110
- References
- 0
- Citations by year
- 2026: 2 · 2024: 5 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 4 · 2015: 5 · 2013: 9 · 2012: 4
- FWCI
- 10.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- oxytocin receptor, gene expression, promoter, 5'-flanking region, species differences, brain, transcriptional regulation, epigenetic factors, transcription factors
- MeSH terms
- Amino Acid Sequence, Animals, Autoradiography, Base Sequence, Arvicolinae, DNA, Female, Iodine Radioisotopes, Male, Molecular Sequence Data, Oxytocin, Promoter Regions, Genetic, Regulatory Sequences, Nucleic Acid, RNA, Messenger, Sequence Homology, Nucleic Acid, Species Specificity, Transcription, Genetic, RNA Probes, Gene Expression, Polymerase Chain Reaction, Prefrontal Cortex, In Situ Hybridization, Receptors, Oxytocin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
