Cited by 97Plant biochemistry and biosynthesisSesquiterpenes and Asteraceae StudiesPlant tissue culture and regeneration

Artemisinin: the biosynthetic pathway and its regulation in Artemisia annua, a terpenoid-rich species

Weathers, Pamela J., Elkholy, Shereen, Wobbe, Kristin K.·2006·In Vitro Cellular & Developmental Biology - Plant

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Crossref · 10.1079/ivp2006782

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  • Terpene biosynthesis and its regulation in A. annua have been well reviewed, including the central role of amorpha-4,11-diene (451) in artemisinin biosynthesis and the likelihood that glandular trichomes are the location of artemisinin biosynthesis.

    “Terpene biosynthesis [271,272,273,274,275,276] and its regulation [277,278] in A. annua have been well reviewed, including the central role of amorpha-4,11-diene (451) in the biosynthesis of artemisinin (495) [279] and the likelihood that glandular trichomes are the location wherein artemisinin biosynthesis actually occurs [244,280]”

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Authors
Weathers, P. J., Elkholy, S., & Wobbe, K. K.
Affiliations
Worcester Polytechnic Institute (US)
Corresponding author
Weathers, Pamela J.
Venue
In Vitro Cellular & Developmental Biology - Plant
Published
2006-07
Volume
42
Issue
4
Pages
309-317
ISSN
  • 1054-5476 (ISSN-L)
  • 1475-2689
OpenAlex
W2097457822
Cited by
97
References
81
Citations by year
2026: 2 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 4 · 2020: 5 · 2019: 5 · 2018: 7 · 2017: 4 · 2016: 9 · 2015: 4 · 2014: 4 · 2013: 9 · 2012: 6
FWCI
1.22
Type
journal article
Language
en
Open access
closed
Locations
  • In Vitro Cellular & Developmental Biology - Plant (publishedVersion)
  • BioOne Complete (BioOne) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
Keywords
artemisinin, Artemisia annua, sesquiterpene lactone biosynthesis, terpenoid biosynthesis, biosynthetic pathway regulation, in vitro production, Plasmodium falciparum, malaria drugs, antimalarial compounds

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