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Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children
Open accessAbstract
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a transgenerational prospective observational study investigating influences on health and development across the life course. It considers multiple genetic, epigenetic, biological, psychological, social and other environmental exposures in relation to a similarly diverse range of health, social and developmental outcomes. Recruitment sought to enroll pregnant women in the Bristol area of the UK during 1990-92; this was extended to include additional children eligible using the original enrollment definition up to the age of 18 years. The children from 14541 pregnancies were recruited in 1990-92, increasing to 15247 pregnancies by the age of 18 years. This cohort profile describes the index children of these pregnancies. Follow-up includes 59 questionnaires (4 weeks-18 years of age) and 9 clinical assessment visits (7-17 years of age). The resource comprises a wide range of phenotypic and environmental measures in addition to biological samples, genetic (DNA on 11343 children, genome-wide data on 8365 children, complete genome sequencing on 2000 children) and epigenetic (methylation sampling on 1000 children) information and linkage to health and administrative records. Data access is described in this article and is currently set up as a supported access resource. To date, over 700 peer-reviewed articles have been published using ALSPAC data.
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In the citing paper
“The ALSPAC birth cohort follows children of 14 062 live births from women living in (the former) Avon County, a geographically defined region in southwest England, with expected dates of delivery between April 1991 and December 1992 (http://www.bristol.ac.uk/alspac).30”
From Variant connective tissue (joint hypermobility) and its relevance to depression and anxiety in adolescents: a cohort-based case–control study (2022) · cites this paper as [30]
Experimental — accuracy not yet measuredIn the citing paper
“We tried to identify outcomes in the ALSPAC cohort67,68 that would be affected by confounders that are important in the relation of breastfeeding to later offspring outcomes but for which a biological/causal effect of breastfeeding was unlikely”
From Triangulation in aetiological epidemiology (2017) · cites this paper as [67]
In the citing paper
“For example, individual participant data from the large UK Biobank (which currently has genotypic, phenotypic and clinical data in up to 500 000 adults76) and the Avon Longitudinal Study of Parents and Children (with very detailed data across three generations across their life course67,68) are available to researchers globally at modest cost”
From Triangulation in aetiological epidemiology (2017) · cites this paper as [67]
In the citing paper
“The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based birth cohort study that recruited 14 541 pregnant women resident in Avon, UK, with expected dates of delivery 1 April 1991 to 31 December 1992.26,27”
From A structured approach to hypotheses involving continuous exposures over the life course (2016) · cites this paper as [27]
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Frayling, T. M., Timpson, N. J., Weedon, M. N., Zeggini, E., Freathy, R. M., Lindgren, C. M., Perry, J. R. B., Elliott, K. S., Lango, H., Rayner, N. W., et al. (2007) · Science · doi:10.1126/science.1141634 · Cited by 4,531
Self-citationCohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
Fraser, A., Macdonald-Wallis, C., Tilling, K., Boyd, A., Golding, J., Davey Smith, G., Henderson, J., Macleod, J., Molloy, L., Ness, A., et al. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dys066 · Cited by 2,494
Self-citationMarmot, M. G., Allen, J., Goldblatt, P., Boyce, T., McNeish, D., Grady, M., & Geddes, I. (2010) · Europe PMC (PubMed Central) · Cited by 1,404
Hibbeln, J. R., Davis, J. M., Steer, C., Emmett, P., Rogers, I., Williams, C., & Golding, J. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60277-3 · Cited by 987
Self-citationFactors Associated with the Development of Peanut Allergy in Childhood
Lack, G., Fox, D., Northstone, K., & Golding, J. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa013536 · Cited by 919
Self-citationFraser, A., Tilling, K., Macdonald-Wallis, C., Sattar, N., Brion, M.-J., Benfield, L., Ness, A., Deanfield, J., Hingorani, A., Nelson, S. M., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.906081 · Cited by 486
Self-citationMattocks, C., Ness, A., Leary, S. D., Tilling, K. M., Blair, S. N., Hamilton-Shield, J. P., Deere, K. C., Saunders, J., Kirkby, J., Smith, G. D., et al. (2008) · Journal of Physical Activity and Health · doi:10.1123/jpah.5.s1.s98 · Cited by 395
Self-citationAre sibling relationships protective? A longitudinal study
Gass, K., Jenkins, J. M., & Dunn, J. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01699.x · Cited by 369
Henderson, J., Northstone, K., Lee, S. P., Liao, H., Zhao, Y., Pembrey, M. E., Mukhopadhyay, S., Smith, G. D., Palmer, C. N. A., McLean, W. H. I., et al. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.01.026 · Cited by 352
Self-citationFish Intake During Pregnancy and Early Cognitive Development of Offspring
Daniels, J. L., Longnecker, M. P., Rowland, A. S., & Golding, J. (2004) · Epidemiology · doi:10.1097/01.ede.0000129514.46451.ce · Cited by 345
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Research works printed but not linked: 4
- Boyd, 2011, Using linkage to health and social administrative records to quantify the response rate to initial recruitment in the Avon Longitudinal Study of Parents and Children (ALSPAC) and assess possible bias associated with non-response (Abstract)
- Marais, 2007, Regional Household Income
- Field, 2010, The Foundation Years: Preventing Poor Children Becoming Poor Adults
- Relton, 2009, Epigenetic epidemiology: evidence for the role of epigenetic variation in complex disease, Ann Nutr Metab, 55, 165
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The UK10K Consortium, Writing group, Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., et al. (2015) · Nature · doi:10.1038/nature14962 · Cited by 1,040
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Munafò, M. R., Tilling, K., Taylor, A. E., Evans, D. M., & Davey Smith, G. (2018) · International Journal of Epidemiology · doi:10.1093/ije/dyx206 · Cited by 813
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Joubert, B. R., Felix, J. F., Yousefi, P., Bakulski, K. M., Just, A. C., Breton, C., Reese, S. E., Markunas, C. A., Richmond, R. C., Xu, C.-J., et al. (2016) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2016.02.019 · Cited by 886
The genetic architecture of the human cerebral cortex
Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Ching, C. R. K., McMahon, M. A. B., et al. (2020) · Science · doi:10.1126/science.aay6690 · Cited by 876
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Khera, A. V., Chaffin, M., Wade, K. H., Zahid, S., Brancale, J., Xia, R., Distefano, M., Senol-Cosar, O., Haas, M. E., Bick, A., et al. (2019) · Cell · doi:10.1016/j.cell.2019.03.028 · Cited by 789
Zheng, J., Haberland, V., Baird, D., Walker, V., Haycock, P., Hurle, M., Gutteridge, A., Erola, P., Liu, Y., Luo, S., et al. (2019) · doi:10.1101/627398 · Cited by 812
Self-citationHolmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014) · BMJ · doi:10.1136/bmj.g4164 · Cited by 669
Self-citation23andMe Research Team, Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., Aliev, F., Bacanu, S.-A., Batzler, A., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0275-1 · Cited by 632
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Netsi, E., Pearson, R. M., Murray, L., Cooper, P., Craske, M. G., & Stein, A. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.4363 · Cited by 632
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Mars, B., Heron, J., Klonsky, E. D., Moran, P., O'Connor, R. C., Tilling, K., Wilkinson, P., & Gunnell, D. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30030-6 · Cited by 546
The atopic march and atopic multimorbidity: many trajectories, many pathways
Paller, A. S., Spergel, J. M., Mina-Osorio, P., & Irvine, A. D. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.11.006 · Cited by 464
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iPSYCH-SSI-Broad Autism Group, Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, S. J., et al. (2016) · Nature Genetics · doi:10.1038/ng.3529 · Cited by 367
Richmond, R. C., Simpkin, A. J., Woodward, G., Gaunt, T. R., Lyttleton, O., McArdle, W. L., Ring, S. M., Smith, A. D. A. C., Timpson, N. J., Tilling, K., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddu739 · Cited by 372
Self-citationZammit, S., Kounali, D., Cannon, M., David, A. S., Gunnell, D., Heron, J., Jones, P. B., Lewis, S., Sullivan, S., Wolke, D., et al. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12060768 · Cited by 319
Patalay, P., & Gage, S. H. (2019) · International Journal of Epidemiology · doi:10.1093/ije/dyz006 · Cited by 335
Pembrey, M., Saffery, R., Bygren, L. O., & Network in Epigenetic Epidemiology (2014) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2014-102577 · Cited by 325
Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study.
Richardson, T. G., Sanderson, E., Elsworth, B., Tilling, K., & Davey Smith, G. (2019) · doi:10.1101/19008011 · Cited by 321
Self-citationDunn, E. C., Soare, T. W., Zhu, Y., Simpkin, A. J., Suderman, M. J., Klengel, T., Smith, A. D. A. C., Ressler, K. J., & Relton, C. L. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.12.023 · Cited by 315
Clinical and social outcomes of adolescent self harm: population based birth cohort study
Mars, B., Heron, J., Crane, C., Hawton, K., Lewis, G., Macleod, J., Tilling, K., & Gunnell, D. (2014) · BMJ · doi:10.1136/bmj.g5954 · Cited by 311
Self-citationMicali, N., Martini, M. G., Thomas, J. J., Eddy, K. T., Kothari, R., Russell, E., Bulik, C. M., & Treasure, J. (2017) · BMC Medicine · doi:10.1186/s12916-016-0766-4 · Cited by 245
Parental Advisory: Maternal and Paternal Stress Can Impact Offspring Neurodevelopment
Chan, J. C., Nugent, B. M., & Bale, T. L. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.10.005 · Cited by 241
Simpkin, A. J., Hemani, G., Suderman, M., Gaunt, T. R., Lyttleton, O., Mcardle, W. L., Ring, S. M., Sharp, G. C., Tilling, K., Horvath, S., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddv456 · Cited by 246
Self-citationCousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt104 · Cited by 209
Self-citationFerreira, M. A. R., Matheson, M. C., Tang, C. S., Granell, R., Ang, W., Hui, J., Kiefer, A. K., Duffy, D. L., Baltic, S., Danoy, P., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.10.030 · Cited by 216
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Validity of the Short Mood and Feelings Questionnaire in late adolescence
Turner, N., Joinson, C., Peters, T. J., Wiles, N., & Lewis, G. (2014) · Psychological Assessment · doi:10.1037/a0036572 · Cited by 198
Wren, Y., Miller, L. L., Peters, T. J., Emond, A., & Roulstone, S. (2016) · Journal of Speech, Language, and Hearing Research · doi:10.1044/2015_jslhr-s-14-0282 · Cited by 198
Taylor, A. E., Jones, H. J., Sallis, H., Euesden, J., Stergiakouli, E., Davies, N. M., Zammit, S., Lawlor, D. A., Munafò, M. R., Davey Smith, G., et al. (2018) · International Journal of Epidemiology · doi:10.1093/ije/dyy060 · Cited by 192
Self-citationSleep patterns in children with autistic spectrum disorders: a prospective cohort study
Humphreys, J. S., Gringras, P., Blair, P. S., Scott, N., Henderson, J., Fleming, P. J., & Emond, A. M. (2014) · Archives of Disease in Childhood · doi:10.1136/archdischild-2013-304083 · Cited by 197
Self-citationMartin, J., Hamshere, M. L., Stergiakouli, E., O’Donovan, M. C., & Thapar, A. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.02.013 · Cited by 187
Mars, B., Heron, J., Klonsky, E. D., Moran, P., O'Connor, R. C., Tilling, K., Wilkinson, P., & Gunnell, D. (2019) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12878 · Cited by 185
Mulder, R. H., Neumann, A., Cecil, C. A. M., Walton, E., Houtepen, L. C., Simpkin, A. J., Rijlaarsdam, J., Heijmans, B. T., Gaunt, T. R., Felix, J. F., et al. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddaa280 · Cited by 165
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Würtz, P., Wang, Q., Soininen, P., Kangas, A. J., Fatemifar, G., Tynkkynen, T., Tiainen, M., Perola, M., Tillin, T., Hughes, A. D., et al. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.12.060 · Cited by 188
Self-citationLee, K. W. K., Richmond, R., Hu, P., French, L., Shin, J., Bourdon, C., Reischl, E., Waldenberger, M., Zeilinger, S., Gaunt, T., et al. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1408614 · Cited by 186
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Rai, D., Culpin, I., Heuvelman, H., Magnusson, C. M. K., Carpenter, P., Jones, H. J., Emond, A. M., Zammit, S., Golding, J., & Pearson, R. M. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.1323 · Cited by 185
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Booth, J. N., Leary, S. D., Joinson, C., Ness, A. R., Tomporowski, P. D., Boyle, J. M., & Reilly, J. J. (2014) · British Journal of Sports Medicine · doi:10.1136/bjsports-2013-092334 · Cited by 177
Self-citationDunn, E. C., Soare, T. W., Raffeld, M. R., Busso, D. S., Crawford, K. M., Davis, K. A., Fisher, V. A., Slopen, N., Smith, A. D. A. C., Tiemeier, H., et al. (2018) · Psychological Medicine · doi:10.1017/s0033291718000181 · Cited by 179
Richmond, R. C., Davey Smith, G., Ness, A. R., den Hoed, M., McMahon, G., & Timpson, N. J. (2014) · PLoS Medicine · doi:10.1371/journal.pmed.1001618 · Cited by 167
Self-citationOrchard, F., Gregory, A. M., Gradisar, M., & Reynolds, S. (2020) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13288 · Cited by 175
Rice, F., Riglin, L., Thapar, A. K., Heron, J., Anney, R., O’Donovan, M. C., & Thapar, A. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.3338 · Cited by 167
The Odense Child Cohort: Aims, Design, and Cohort Profile
Kyhl, H. B., Jensen, T. K., Barington, T., Buhl, S., Norberg, L. A., Jørgensen, J. S., Jensen, D. F. G., Christesen, H. T., Lamont, R. F., & Husby, S. (2015) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12183 · Cited by 166
Riglin, L., Collishaw, S., Thapar, A. K., Dalsgaard, S., Langley, K., Smith, G. D., Stergiakouli, E., Maughan, B., O’Donovan, M. C., & Thapar, A. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.2817 · Cited by 161
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White, J. D., Indencleef, K., Naqvi, S., Eller, R. J., Hoskens, H., Roosenboom, J., Lee, M. K., Li, J., Mohammed, J., Richmond, S., et al. (2021) · Nature Genetics · doi:10.1038/s41588-020-00741-7 · Cited by 166
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Course of Cognitive Development From Infancy to Early Adulthood in the Psychosis Spectrum
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Mood, anxiety and psychotic phenomena measure a common psychopathological factor
Stochl, J., Khandaker, G. M., Lewis, G., Perez, J., Goodyer, I. M., Zammit, S., Sullivan, S., Croudace, T. J., & Jones, P. B. (2015) · Psychological Medicine · doi:10.1017/s003329171400261x · Cited by 153
Maud, C., Ryan, J., McIntosh, J. E., & Olsson, C. A. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1740-9 · Cited by 151
“longitudinal cohort studies for epigenetic analysis [63].”
Adolescent self-harm and suicidal thoughts in the ALSPAC cohort: a self-report survey in England
Kidger, J., Heron, J., Lewis, G., Evans, J., & Gunnell, D. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-69 · Cited by 148
Tobias, J. H., Deere, K., Palmer, S., Clark, E. M., & Clinch, J. (2013) · Arthritis & Rheumatism · doi:10.1002/art.37836 · Cited by 145
Cross-cohort change in adolescent outcomes for children with mental health problems
Sellers, R., Warne, N., Pickles, A., Maughan, B., Thapar, A., & Collishaw, S. (2019) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13029 · Cited by 134
The many weak instruments problem and Mendelian randomization
Davies, N. M., von Hinke Kessler Scholder, S., Farbmacher, H., Burgess, S., Windmeijer, F., & Smith, G. D. (2015) · Statistics in Medicine · doi:10.1002/sim.6358 · Cited by 140
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Wang, Q., Ferreira, D. L. S., Nelson, S. M., Sattar, N., Ala-Korpela, M., & Lawlor, D. A. (2018) · BMC Medicine · doi:10.1186/s12916-018-1008-8 · Cited by 134
Self-citationiPSYCH-SSI-Broad Autism Group, St Pourcain, B., Robinson, E. B., Anttila, V, Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., et al. (2018) · Molecular Psychiatry · doi:10.1038/mp.2016.198 · Cited by 125
Self-citationDNA methylation links prenatal smoking exposure to later life health outcomes in offspring
Wiklund, P., Karhunen, V., Richmond, R. C., Parmar, P., Rodriguez, A., De Silva, M., Wielscher, M., Rezwan, F. I., Richardson, T. G., Veijola, J., et al. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0683-4 · Cited by 120
Lawlor, D. A. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dys209 · Cited by 114
Self-citationThe development of autistic social traits across childhood and adolescence in males and females
Mandy, W., Pellicano, L., St Pourcain, B., Skuse, D., & Heron, J. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12913 · Cited by 117
Fraser, A., Nelson, S. M., Macdonald-Wallis, C., & Lawlor, D. A. (2012) · Experimental Diabetes Research · doi:10.1155/2012/963735 · Cited by 112
Self-citationMetabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment
Sliz, E., Kettunen, J., Holmes, M. V., Williams, C. O., Boachie, C., Wang, Q., Männikkö, M., Sebert, S., Walters, R., Lin, K., et al. (2018) · Circulation · doi:10.1161/circulationaha.118.034942 · Cited by 109
Self-citationSchoeler, T., Choi, S. W., Dudbridge, F., Baldwin, J., Duncan, L., Cecil, C. M., Walton, E., Viding, E., McCrory, E., & Pingault, J.-B. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.0310 · Cited by 105
Kern, C., Wan, J., LeWinn, K. Z., Ramirez, F. D., Lee, Y., McCulloch, C. E., Langan, S. M., & Abuabara, K. (2021) · JAMA Dermatology · doi:10.1001/jamadermatol.2021.2657 · Cited by 103
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Cecil, C. A. M., Walton, E., Smith, R. G., Viding, E., McCrory, E. J., Relton, C. L., Suderman, M., Pingault, J.-B., McArdle, W., Gaunt, T. R., et al. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.247 · Cited by 101
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Self-citationStergiakouli, E., Martin, J., Hamshere, M. L., Langley, K., Evans, D. M., St Pourcain, B., Timpson, N. J., Owen, M. J., O'Donovan, M., Thapar, A., et al. (2015) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2015.01.010 · Cited by 94
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Rodgers, A. B., & Bale, T. L. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.03.018 · Cited by 91
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Gutierrez-Galve, L., Stein, A., Hanington, L., Heron, J., Lewis, G., O’Farrelly, C., & Ramchandani, P. G. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.3667 · Cited by 85
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“…ALSPAC birth cohort comprises 14,062 live births from pregnant women resident in county Avon, a geographically de fi ned region in southwest of England, with expected dates of delivery between April 1991 and December 1992 (http://www.bristol.ac.uk/ alspac/) (Boyd et al., 2013; Fraser et al., 2013).”
Martin, J., Taylor, M. J., Rydell, M., Riglin, L., Eyre, O., Lu, Y., Lundström, S., Larsson, H., Thapar, A., & Lichtenstein, P. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12874 · Cited by 57
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A structured approach to hypotheses involving continuous exposures over the life course
Smith, A. D. A. C., Hardy, R., Heron, J., Joinson, C. J., Lawlor, D. A., Macdonald-Wallis, C., & Tilling, K. (2016) · International Journal of Epidemiology · doi:10.1093/ije/dyw164 · Cited by 59
Self-citationChildhood IQ and risk of bipolar disorder in adulthood: prospective birth cohort study
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Metadata
- Authors
- Boyd, A., Golding, J., Macleod, J., Lawlor, D. A., Fraser, A., Henderson, J., Molloy, L., Ness, A., Ring, S., & Davey Smith, G.
- Affiliations
- University of Bristol (GB)
- Corresponding author
- Boyd, Andy
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-04-16
- Volume
- 42
- Issue
- 1
- Pages
- 111-127
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- PMC
- PMC3600618
- OpenAlex
- W2123263006
- Cited by
- 2,996
- References
- 35
- Citations by year
- 2026: 158 · 2025: 242 · 2024: 243 · 2023: 253 · 2022: 280 · 2021: 344 · 2020: 257 · 2019: 243 · 2018: 216 · 2017: 162 · 2016: 157 · 2015: 143 · 2014: 150 · 2013: 126 · 2012: 21
- FWCI
- 122.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- International Journal of Epidemiology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- HighWire Press Open Archive (acceptedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion, cc-by-nc)
- Bristol Research (University of Bristol) (submittedVersion)
- Funders
- Wellcome Trust (WT086118, WT086118/Z/08/Z, G0600705, G0701594, 092731, WT092731, 86118/Z/08/Z)
- University of Bristol (G0600705)
- Medical Research Council (G0701594, G0600705)
- Economic and Social Research Council (ES/G007543/1)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- Avon Longitudinal Study of Parents and Children, birth cohort, child development, health outcomes, epigenetics, DNA methylation, genome-wide data, genome sequencing, life course, data access
- MeSH terms
- Adolescent, Anthropometry, Blood Banks, Child, Child Development, England, Environment, Female, Health Status, Humans, Longitudinal Studies, Male, Medical Record Linkage, Parents, Phenotype, Pregnancy, Surveys and Questionnaires, Socioeconomic Factors, Health Behavior, History, 20th Century, Genome-Wide Association Study
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