The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Supplemental Protein in Support of Muscle Mass and Health: Advantage Whey
Abstract
Skeletal muscle is an integral body tissue playing key roles in strength, performance, physical function, and metabolic regulation. It is essential for athletes to ensure that they have optimal amounts of muscle mass to ensure peak performance in their given sport. However, the role of maintaining muscle mass during weight loss and as we age is an emerging concept, having implications in chronic disease prevention, functional capacity, and quality of life. Higher‐protein diets have been shown to: (1) promote gains in muscle mass, especially when paired with resistance training; (2) spare muscle mass loss during caloric restriction; and (3) attenuate the natural loss of muscle mass that accompanies aging. Protein quality is important to the gain and maintenance of muscle mass. Protein quality is a function of protein digestibility, amino acid content, and the resulting amino acid availability to support metabolic function. Whey protein is one of the highest‐quality proteins given its amino acid content (high essential, branched‐chain, and leucine amino acid content) and rapid digestibility. Consumption of whey protein has a robust ability to stimulate muscle protein synthesis. In fact, whey protein has been found to stimulate muscle protein synthesis to a greater degree than other proteins such as casein and soy. This review examines the existing data supporting the role for protein consumption, with an emphasis on whey protein, in the regulation of muscle mass and body composition in response to resistance training, caloric restriction, and aging.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., et al. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.05.021 · Cited by 2,553
Self-citationDeutz, N. E. P., Bauer, J. M., Barazzoni, R., Biolo, G., Boirie, Y., Bosy-Westphal, A., Cederholm, T., Cruz-Jentoft, A., Krznariç, Z., Nair, K. S., et al. (2014) · Clinical Nutrition · doi:10.1016/j.clnu.2014.04.007 · Cited by 1,738
Slow and fast dietary proteins differently modulate postprandial protein accretion
Boirie, Y., Dangin, M., Gachon, P., Vasson, M.-P., Maubois, J.-L., & Beaufrère, B. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14930 · Cited by 1,453
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
Cuthbertson, D., Smith, K., Babraj, J., Leese, G., Waddell, T., Atherton, P., Wackerhage, H., Taylor, P. M., & Rennie, M. J. (2005) · The FASEB Journal · doi:10.1096/fj.04-2640fje · Cited by 1,211
Mixed muscle protein synthesis and breakdown after resistance exercise in humans
Phillips, S. M., Tipton, K. D., Aarsland, A., Wolf, S. E., & Wolfe, R. R. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.1.e99 · Cited by 1,132
Self-citationTang, J. E., Moore, D. R., Kujbida, G. W., Tarnopolsky, M. A., & Phillips, S. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00076.2009 · Cited by 998
Self-citationMoore, D. R., Robinson, M. J., Fry, J. L., Tang, J. E., Glover, E. I., Wilkinson, S. B., Prior, T., Tarnopolsky, M. A., & Phillips, S. M. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26401 · Cited by 973
Self-citationSarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study
Landi, F., Liperoti, R., Russo, A., Giovannini, S., Tosato, M., Capoluongo, E., Bernabei, R., & Onder, G. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2012.02.007 · Cited by 938
Katsanos, C. S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A., & Wolfe, R. R. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00488.2005 · Cited by 923
Cermak, N. M., Res, P. T., de Groot, L. C., Saris, W. H., & van Loon, L. J. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.037556 · Cited by 827
Research works printed but not linked: 55
- 10.1093/jn/130.10.2413 · DOI · Paper page
- 10.3945/jn.111.139840 · DOI · Paper page
- 10.1016/j.jand.2013.01.014 · DOI · Paper page
- 10.1152/ajpendo.1997.273.1.E122 · DOI · Paper page
- 10.1007/s00421-005-0127-z · DOI · Paper page
- 10.1093/jn/133.5.1308 · DOI · Paper page
- 10.3945/ajcn.112.037119 · DOI · Paper page
- 10.1038/ijo.2008.278 · DOI · Paper page
- Coburn JW, 2006, Effects of leucine and whey protein supplementation during eight weeks of unilateral resistance training, J Strength Cond Res, 20, 284
- 10.1093/jn/135.3.376 · DOI · Paper page
- 10.1007/s12603-014-0465-9 · DOI
- 10.2337/diacare.15.3.318 · DOI · Paper page
- 10.1186/1550-2783-6-8 · DOI · Paper page
- 10.1152/ajpendo.00402.2005 · DOI
- 10.1111/j.1469-7793.2001.00301.x · DOI · Paper page
- 10.1093/jn/132.1.125 · DOI
- 10.1152/ajpregu.00281.2009 · DOI
- 10.1186/1743-7075-5-8 · DOI
- 10.1016/j.nutres.2013.05.014 · DOI
- 10.3945/jn.113.184705 · DOI
- 10.1093/ajcn/86.2.373 · DOI · Paper page
- 10.1093/ajcn/87.1.150 · DOI · Paper page
- 10.1038/ejcn.2013.52 · DOI
- 10.3945/jn.111.141028 · DOI · Paper page
- 10.1249/01.mss.0000175865.17614.74 · DOI · Paper page
- 10.1016/j.biocel.2010.05.013 · DOI
- 10.1152/ajpendo.00413.2004 · DOI · Paper page
- 10.1038/ejcn.2011.221 · DOI
- 10.1093/jn/135.5.1080 · DOI
- 10.1161/CIRCULATIONAHA.107.716159 · DOI · Paper page
- 10.1093/gerona/glr120 · DOI
- 10.1093/gerona/glu103 · DOI · Paper page
- 10.1093/ajcn/66.4.760 · DOI · Paper page
- 10.1093/ajcn/77.6.1417 · DOI · Paper page
- 10.1097/MCO.0b013e32831cef8b · DOI · Paper page
- 10.1017/S0007114510001911 · DOI
- 10.3945/ajcn.110.008102 · DOI · Paper page
- 10.1001/jama.287.16.2081 · DOI · Paper page
- 10.1139/H09-042 · DOI
- 10.1007/s40279-014-0152-3 · DOI · Paper page
- 10.1136/bmj.a439 · DOI · Paper page
- 10.1007/s00198-013-2431-5 · DOI
- 10.1186/1550-2783-9-54 · DOI
- Stookey J, 2005, Do protein and energy intakes explain long‐term changes in body composition, J Nutr Health Aging, 9, 5
- 10.1249/01.MSS.0000147582.99810.C5 · DOI · Paper page
- Velazquez Alva Mdel C, 2013, The relationship between sarcopenia, undernutrition, physical mobility and basic activities of daily living in a group of elderly women of Mexico City, Nutr Hosp, 28, 514
- 10.3945/ajcn.2008.26626 · DOI · Paper page
- 10.1210/jc.85.12.4481 · DOI · Paper page
- 10.1093/gerona/gls229 · DOI · Paper page
- 10.3945/ajcn.111.013722 · DOI · Paper page
- 10.1146/annurev-nutr-080508-141056 · DOI · Paper page
- 10.1093/ajcn/85.4.1031 · DOI · Paper page
- 10.1093/ajcn/84.3.475 · DOI · Paper page
- 10.1016/j.clnu.2008.06.008 · DOI · Paper page
- 10.1111/j.1463-1326.2010.01307.x · DOI
Cited by
ISSN exercise & sports nutrition review update: research & recommendations
Kerksick, C. M., Wilborn, C. D., Roberts, M. D., Smith-Ryan, A., Kleiner, S. M., Jäger, R., Collins, R., Cooke, M., Davis, J. N., Galvan, E., et al. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0242-y · Cited by 945
The Role of Inflammation in Age-Related Sarcopenia
Dalle, S., Rossmeislova, L., & Koppo, K. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.01045 · Cited by 668
New strategies in sport nutrition to increase exercise performance
Close, G. L., Hamilton, D. L., Philp, A., Burke, L. M., & Morton, J. P. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.01.016 · Cited by 221
Strategies to Prevent Sarcopenia in the Aging Process: Role of Protein Intake and Exercise
Rogeri, P. S., Zanella, R., Martins, G. L., Garcia, M. D. A., Leite, G., Lugaresi, R., Gasparini, S. O., Sperandio, G. A., Ferreira, L. H. B., Souza-Junior, T. P., et al. (2021) · Nutrients · doi:10.3390/nu14010052 · Cited by 181
Devries, M. C., McGlory, C., Bolster, D. R., Kamil, A., Rahn, M., Harkness, L., Baker, S. K., & Phillips, S. M. (2018) · The Journal of Nutrition · doi:10.1093/jn/nxy091 · Cited by 141
Protein Considerations for Optimising Skeletal Muscle Mass in Healthy Young and Older Adults
Witard, O., Wardle, S., Macnaughton, L., Hodgson, A., & Tipton, K. (2016) · Nutrients · doi:10.3390/nu8040181 · Cited by 132
Nabuco, H. C. G., Tomeleri, C. M., Fernandes, R. R., Sugihara Junior, P., Cavalcante, E. F., Cunha, P. M., Antunes, M., Nunes, J. P., Venturini, D., Barbosa, D. S., et al. (2019) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2019.04.007 · Cited by 125
Messina, M., Lynch, H., Dickinson, J. M., & Reed, K. E. (2018) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2018-0071 · Cited by 120
Pre-Sleep Protein Ingestion to Improve the Skeletal Muscle Adaptive Response to Exercise Training
Trommelen, J., & Van Loon, L. (2016) · Nutrients · doi:10.3390/nu8120763 · Cited by 116
Naclerio, F., & Larumbe-Zabala, E. (2016) · Sports Medicine · doi:10.1007/s40279-015-0403-y · Cited by 106
Slater, G. J., Dieter, B. P., Marsh, D. J., Helms, E. R., Shaw, G., & Iraki, J. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00131 · Cited by 88
Prospective views for whey protein and/or resistance training against age-related sarcopenia
Liao, Y., Peng, Z., Chen, L., Zhang, Y., Cheng, Q., Nüssler, A. K., Bao, W., Liu, L., & Yang, W. (2019) · Aging and Disease · doi:10.14336/ad.2018.0325 · Cited by 68
Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Deer, R. R., Husaini, S. H., Walker, D. K., Igbinigie, S., Robertson, S. M., Cope, M. B., et al. (2016) · The Journal of Nutrition · doi:10.3945/jn.116.231803 · Cited by 67
“WP 3 (29, 16) 13 (21, 26) MDP 1 (211, 14) 3 (210, 17)”
BackgroundInfluentialMetabolic time-course response after resistance exercise: A metabolomics approach
Berton, R., Conceição, M. S., Libardi, C. A., Canevarolo, R. R., Gáspari, A. F., Chacon-Mikahil, M. P. T., Zeri, A. C., & Cavaglieri, C. R. (2017) · Journal of Sports Sciences · doi:10.1080/02640414.2016.1218035 · Cited by 65
Shin, J. E., Park, S. J., Ahn, S. I., & Choung, S.-Y. (2020) · Nutrients · doi:10.3390/nu12113362 · Cited by 52
Churchward-Venne, T. A., Pinckaers, P. J. M., Smeets, J. S. J., Peeters, W. M., Zorenc, A. H., Schierbeek, H., Rollo, I., Verdijk, L. B., & van Loon, L. J. C. (2019) · The Journal of Nutrition · doi:10.1093/jn/nxy251 · Cited by 51
Vangsoe, M., Joergensen, M., Heckmann, L.-H., & Hansen, M. (2018) · Nutrients · doi:10.3390/nu10030335 · Cited by 44
Protein Supplementation in Sport: Source, Timing, and Intended Benefits
Huecker, M., Sarav, M., Pearlman, M., & Laster, J. (2019) · Current Nutrition Reports · doi:10.1007/s13668-019-00293-1 · Cited by 37
Arciero, P., Edmonds, R., Bunsawat, K., Gentile, C., Ketcham, C., Darin, C., Renna, M., Zheng, Q., Zhang, J., & Ormsbee, M. (2016) · Nutrients · doi:10.3390/nu8050288 · Cited by 25
Oliveira, G. S., Vieira, F. T., Lamarca, F., Lima, R. M., Carvalho, K. M. B., & Dutra, E. S. (2021) · Nutrients · doi:10.3390/nu14010014 · Cited by 22
Kuo, Y.-Y., Chang, H.-Y., Huang, Y.-C., & Liu, C.-W. (2022) · Nutrients · doi:10.3390/nu14194210 · Cited by 22
Giglio, B. M., Lobo, P. C. B., & Pimentel, G. D. (2023) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.09.014 · Cited by 18
Minevich, J., Olson, M. A., Mannion, J. P., Boublik, J. H., McPherson, J. O., Lowery, R. P., Shields, K., Sharp, M., De Souza, E. O., Wilson, J. M., et al. (2015) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-12-s1-p26 · Cited by 14
Yapici, H., Gülü, M., Yagin, F. H., Ugurlu, D., Comertpay, E., Eroglu, O., Kocoğlu, M., Aldhahi, M. I., Karayigit, R., & Badri AL-Mhanna, S. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1148494 · Cited by 13
Al-Rawhani, A. H., Adznam, S. N., Abu Zaid, Z., Md. Yusop, N. B., M. Sallehuddin, H., & Alshawsh, M. A. (2024) · Clinical Nutrition · doi:10.1016/j.clnu.2024.08.033 · Cited by 13
Batsis, J. A., Petersen, C. L., Cook, S. B., Al-Nimr, R. I., Driesse, T., Pidgeon, D., & Fielding, R. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.07.006 · Cited by 3
Metadata
- Authors
- Devries, M. C., & Phillips, S. M.
- Venue
- Journal of Food Science
- Publisher
- Wiley
- Published
- 2015-03
- Volume
- 80
- Issue
- S1
- Pages
- A8-A15
- ISSN
- 0022-1147 (ISSN-L)
- 1750-3841
- OpenAlex
- W1731095862
- Cited by
- 330
- References
- 41
- Type
- supplementary materials
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.