Cited by 208Marine Invertebrate Physiology and EcologyDevelopmental Biology and Gene RegulationNeurobiology and Insect Physiology Research

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Cnidarians and the evolutionary origin of the nervous system

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Watanabe, Hiroshi, Fujisawa, Toshitaka, Holstein, Thomas W.·2009·Development, Growth & Differentiation

DOI 10.1111/j.1440-169x.2009.01103.x

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Abstract

Cnidarians are widely regarded as one of the first organisms in animal evolution possessing a nervous system. Conventional histological and electrophysiological studies have revealed a considerable degree of complexity of the cnidarian nervous system. Thanks to expressed sequence tags and genome projects and the availability of functional assay systems in cnidarians, this simple nervous system is now genetically accessible and becomes particularly valuable for understanding the origin and evolution of the genetic control mechanisms underlying its development. In the present review, the anatomical and physiological features of the cnidarian nervous system and the interesting parallels in neurodevelopmental mechanisms between Cnidaria and Bilateria are discussed.

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Invertebrate neurophylogeny: suggested terms and definitions for a neuroanatomical glossary
Richter, S., Loesel, R., Purschke, G., Schmidt‐Rhaesa, A., Scholtz, G., Stach, T., Vogt, L., Wanninger, A., Brenneis, G., Döring, C., et al. (2010) · Frontiers in Zoology · doi:10.1186/1742-9994-7-29 · Cited by 334
“The nervous system of Cnidaria and Ctenophora is typically organized as a plexus which functions as a nerve net [18,190,220,276,277].”
Background
From nerve net to nerve ring, nerve cord and brain — evolution of the nervous system
Arendt, D., Tosches, M. A., & Marlow, H. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2015.15 · Cited by 279
The Jellyfish Cassiopea Exhibits a Sleep-like State
Nath, R. D., Bedbrook, C. N., Abrams, M. J., Basinger, T., Bois, J. S., Prober, D. A., Sternberg, P. W., Gradinaru, V., & Goentoro, L. (2017) · Current Biology · doi:10.1016/j.cub.2017.08.014 · Cited by 260
Unraveling the evolutionary determinants of sleep
Joiner, W. J. (2016) · Current Biology · doi:10.1016/j.cub.2016.08.068 · Cited by 232
RETRACTED: Chemically mediated behavior of recruiting corals and fishes: A tipping point that may limit reef recovery
Dixson, D. L., Abrego, D., & Hay, M. E. (2014) · Science · doi:10.1126/science.1255057 · Cited by 216
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Authors: Watanabe, H., Fujisawa, T., & Holstein, T. W.
Affiliations: Heidelberg University (DE)
Corresponding author: Watanabe, Hiroshi
Holstein, Thomas W.
ORCID: Watanabe, Hiroshi
Holstein, Thomas W.
Venue: Development, Growth & Differentiation
Publisher: Wiley
Published: 2009-03-30
Volume: 51
Issue: 3
Pages: 167-183
ISSN: 0012-1592 (ISSN-L)
1440-169X
DOI: 10.1111/j.1440-169x.2009.01103.x
OpenAlex: W1636647670
Cited by: 206
References: 191
Citations by year: 2026: 6 · 2025: 11 · 2024: 16 · 2023: 9 · 2022: 16 · 2021: 26 · 2020: 13 · 2019: 17 · 2018: 7 · 2017: 8 · 2016: 10 · 2015: 19 · 2014: 15 · 2013: 5 · 2012: 8
FWCI: 0.96
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Development Growth & Differentiation (publishedVersion)
PubMed (publishedVersion)
Funders: Alexander von Humboldt-Stiftung
Toyobo Biotechnology Foundation
Deutsche Forschungsgemeinschaft (SFB 488)
Topics: Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Marine Invertebrate Physiology and Ecology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
Keywords: Cnidaria, nervous system evolution, brain development, Bilateria, comparative neuroanatomy
MeSH terms: Animals, Cnidaria, Biological Evolution, Nervous System, Phylogeny

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Cnidarians and the evolutionary origin of the nervous system

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