Cited by 247Nutrition and Health in AgingBody Composition Measurement TechniquesFrailty in Older Adults

The DOI matches its Crossref record; 131 of the 133 references it cites were found in a registry or an index.

Deciphering the “obesity paradox” in the elderly: A systematic review and meta‐analysis of sarcopenic obesity

Liu, Chaoran, Wong, Pui Yan, Chung, Yik Lok, Chow, Simon Kwoon‐Ho, Cheung, Wing Hoi, Law, Sheung Wai, Chan, Juliana Chung Ngor, Wong, Ronald Man Yeung·2023·Obesity Reviews

DOI 10.1111/obr.13534

Open this paper in CoChat — free account

Abstract

Summary: Aging and obesity are two global concerns in public health. Sarcopenic obesity (SO), defined as the combination of age‐related sarcopenia and obesity, has become a pressing issue. This systematic review and meta‐analysis summarize the current clinical evidence relevant to SO. PubMed, Embase, and Web of Science were searched, and 106 clinical studies with 167,151 elderlies were included. The estimated prevalence of SO was 9% in both men and women. Obesity was associated with 34% reduced risk of sarcopenia (odds ratio [OR] 0.66, 95% CI 0.48–0.91; p < 0.001). The pooled hazard ratio (HR) of all‐cause mortality was 1.51 (95% CI 1.14–2.02; p < 0.001) for people with SO compared with healthy individuals. SO was associated with increased risk of cardiovascular disease and related mortality, metabolic disorders, cognitive impairment, arthritis, functional limitation, and lung diseases (all ORs > 1.0, p < 0.05). The attenuated risk of sarcopenia in elderlies with obesity (“obesity paradox”) was dependent on higher muscle mass and strength. Apart from unifying the diagnosis of SO, more research is needed to subphenotype people with obesity and sarcopenia for individualized treatment. Meanwhile, the maintenance of proper body composition of muscle and fat may delay or attenuate the adverse outcomes of aging.

Integrity signals

Registry

Crossref · 10.1111/obr.13534

Cites

131 of 131 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
Untitled work
(2014) · Medical Entomology and Zoology · Cited by 17,633
Sarcopenia: revised European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Bahat, G., Bauer, J., Boirie, Y., Bruyère, O., Cederholm, T., Cooper, C., Landi, F., Rolland, Y., Sayer, A. A., et al. (2019) · Age and Ageing · doi:10.1093/ageing/afy169 · Cited by 13,818
Sarcopenia: European consensus on definition and diagnosis
Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601
Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment
Chen, L.-K., Woo, J., Assantachai, P., Auyeung, T.-W., Chou, M.-Y., Iijima, K., Jang, H. C., Kang, L., Kim, M., Kim, S., et al. (2020) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2019.12.012 · Cited by 7,070
Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia
Chen, L.-K., Liu, L.-K., Woo, J., Assantachai, P., Auyeung, T.-W., Bahyah, K. S., Chou, M.-Y., Chen, L.-Y., Hsu, P.-S., Krairit, O., et al. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.11.025 · Cited by 4,051
Sarcopenia
Cruz-Jentoft, A. J., & Sayer, A. A. (2019) · The Lancet · doi:10.1016/s0140-6736(19)31138-9 · Cited by 3,905
The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates
Studenski, S. A., Peters, K. W., Alley, D. E., Cawthon, P. M., McLean, R. R., Harris, T. B., Ferrucci, L., Guralnik, J. M., Fragala, M. S., Kenny, A. M., et al. (2014) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glu010 · Cited by 2,545
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
Delmonico, M. J., Harris, T. B., Visser, M., Park, S. W., Conroy, M. B., Velasquez-Mieyer, P., Boudreau, R., Manini, T. M., Nevitt, M., Newman, A. B., et al. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28047 · Cited by 1,446
Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta-analysis
Yeung, S. S. Y., Reijnierse, E. M., Pham, V. K., Trappenburg, M. C., Lim, W. K., Meskers, C. G. M., & Maier, A. B. (2019) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12411 · Cited by 1,115
Body Composition in Healthy Aging
BAUMGARTNER, R. N. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06498.x · Cited by 1,078
Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
Shafiee, G., Keshtkar, A., Soltani, A., Ahadi, Z., Larijani, B., & Heshmat, R. (2017) · Journal of Diabetes & Metabolic Disorders · doi:10.1186/s40200-017-0302-x · Cited by 1,076
Skeletal muscle inflammation and insulin resistance in obesity
Wu, H., & Ballantyne, C. M. (2017) · Journal of Clinical Investigation · doi:10.1172/jci88880 · Cited by 695
Running-induced systemic cathepsin B secretion is associated with memory function
Moon, H. Y., Becke, A., Berron, D., Becker, B., Sah, N., Benoni, G., Janke, E., Lubejko, S. T., Greig, N. H., Mattison, J. A., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.05.025 · Cited by 628
Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean longitudinal study on health and aging (KLoSHA)
Lim, S., Kim, J. H., Yoon, J. W., Kang, S. M., Choi, S. H., Park, Y. J., Kim, K. W., Lim, J. Y., Park, K. S., & Jang, H. C. (2010) · Diabetes Care · doi:10.2337/dc10-0107 · Cited by 588
Body-mass index and obesity in urban and rural China: findings from consecutive nationally representative surveys during 2004–18
Wang, L., Zhou, B., Zhao, Z., Yang, L., Zhang, M., Jiang, Y., Li, Y., Zhou, M., Wang, L., Huang, Z., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00798-4 · Cited by 585
Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement
Donini, L. M., Busetto, L., Bischoff, S. C., Cederholm, T., Ballesteros-Pomar, M. D., Batsis, J. A., Bauer, J. M., Boirie, Y., Cruz-Jentoft, A. J., Dicker, D., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2021.11.014 · Cited by 566 · cited 1×
“Interestingly, a category termed “sarcopenic obesity (SO),” defined as the combination of sarcopenia and obesity, also occurs and has led to growing interests.(15) It has been estimated that 1 in 10 elderly were diagnosed with SO.”
Background
Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Population‐Based Cohort Study of Older Men
Atkins, J. L., Whincup, P. H., Morris, R. W., Lennon, L. T., Papacosta, O., & Wannamethee, S. G. (2014) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12652 · Cited by 509
Obesity Paradox Does Exist
Hainer, V., & Aldhoon-Hainerová, I. (2013) · Diabetes Care · doi:10.2337/dcs13-2023 · Cited by 503
Grip Strength Predicts Cause-Specific Mortality in Middle-Aged and Elderly Persons
Sasaki, H., Kasagi, F., Yamada, M., & Fujita, S. (2007) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.04.018 · Cited by 500
The impact of obesity on skeletal muscle strength and structure through adolescence to old age
Tomlinson, D. J., Erskine, R. M., Morse, C. I., Winwood, K., & Onambélé-Pearson, G. (2016) · Biogerontology · doi:10.1007/s10522-015-9626-4 · Cited by 496
Predicted lean body mass, fat mass, and all cause and cause specific mortality in men: Prospective us cohort study
Lee, D. H., Keum, N., Hu, F. B., Orav, E. J., Rimm, E. B., Willett, W. C., & Giovannucci, E. L. (2018) · BMJ · doi:10.1136/bmj.k2575 · Cited by 486
Do muscle mass, muscle density, strength, and physical function similarly influence risk of hospitalization in older adults?
Cawthon, P. M., Fox, K. M., Gandra, S. R., Delmonico, M. J., Chiou, C., Anthony, M. S., Sewall, A., Goodpaster, B., Satterfield, S., Cummings, S. R., et al. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02366.x · Cited by 414
Exercise hormone irisin is a critical regulator of cognitive function
Islam, M. R., Valaris, S., Young, M. F., Haley, E. B., Luo, R., Bond, S. F., Mazuera, S., Kitchen, R. R., Caldarone, B. J., Bettio, L. E. B., et al. (2021) · Nature Metabolism · doi:10.1038/s42255-021-00438-z · Cited by 403
Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study
Kim, T. N., Yang, S. J., Yoo, H. J., Lim, K. I., Kang, H. J., Song, W., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., et al. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.130 · Cited by 401 · cited 1×
“05).(57,58) Compared to their healthy counterparts, people with SO had similar risk for fracture and osteoporosis (Figure S9).”
Background
Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies
Zheng, H., & Chen, C. (2015) · BMJ Open · doi:10.1136/bmjopen-2014-007568 · Cited by 397
Global prevalence of sarcopenic obesity in older adults: A systematic review and meta-analysis
Gao, Q., Mei, F., Shang, Y., Hu, K., Chen, F., Zhao, L., & Ma, B. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.06.009 · Cited by 376
Computed tomographic measurements of thigh muscle cross-sectional area and attenuation coefficient predict hip fracture: the health, aging, and body composition study
Lang, T., Cauley, J. A., Tylavsky, F., Bauer, D., Cummings, S., & Harris, T. B. (2010) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.090807 · Cited by 371
Malnutrition and sarcopenia
Sieber, C. C. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01170-1 · Cited by 365
Skeletal muscle and mortality results from the InCHIANTI study
Cesari, M., Pahor, M., Lauretani, F., Zamboni, V., Bandinelli, S., Bernabei, R., Guralnik, J. M., & Ferrucci, L. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gln031 · Cited by 346
Critical appraisal of definitions and diagnostic criteria for sarcopenic obesity based on a systematic review
Donini, L. M., Busetto, L., Bauer, J. M., Bischoff, S., Boirie, Y., Cederholm, T., Cruz-Jentoft, A. J., Dicker, D., Frühbeck, G., Giustina, A., et al. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2019.11.024 · Cited by 326
Aging in adipocytes: Potential impact of inherent, depot-specific mechanisms
CARTWRIGHT, M., TCHKONIA, T., & KIRKLAND, J. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2007.03.003 · Cited by 318 · cited 1×
“muscle.(5,6) Transcriptome profiles of skeletal muscle in healthy aged populations showed altered lipid metabolism postulated as one of the pathogenesis of sarcopenia.”
Background
Sarcopenic/Obesity and Physical Capacity in Older Men and Women: Data From the Nutrition as a Determinant of Successful Aging (NuAge)—the Quebec Longitudinal Study
Bouchard, D. R., Dionne, I. J., & Brochu, M. (2009) · Obesity · doi:10.1038/oby.2009.109 · Cited by 314
Does the amount of fat mass predict age-related loss of lean mass, muscle strength, and muscle quality in older adults?
Koster, A., Ding, J., Stenholm, S., Caserotti, P., Houston, D. K., Nicklas, B. J., You, T., Lee, J. S., Visser, M., Newman, A. B., et al. (2011) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glr070 · Cited by 274
Obesity and ageing: Two sides of the same coin
Tam, B. T., Morais, J. A., & Santosa, S. (2020) · Obesity Reviews · doi:10.1111/obr.12991 · Cited by 274
Physical Performance Measures as Predictors of Mortality in a Cohort of Community-dwelling Older French Women
Rolland, Y., Lauwers‐Cancès, V., Cesari, M., Vellas, B. J., Pahor, M., & Grandjean, H. (2006) · European Journal of Epidemiology · doi:10.1007/s10654-005-5458-x · Cited by 262
Prevalence, Pathophysiology, Health Consequences and Treatment Options of Obesity in the Elderly: A Guideline
Mathus-Vliegen, E. M. H., Basdevant, A., Finer, N., Hainer, V., Hauner, H., Micic, D., Maislos, M., Roman, G., Schutz, Y., Tsigos, C., et al. (2012) · Obesity Facts · doi:10.1159/000341193 · Cited by 261
Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?
Fisman, E. Z., & Tenenbaum, A. (2014) · Cardiovascular Diabetology · doi:10.1186/1475-2840-13-103 · Cited by 245
Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study
Abramowitz, M. K., Hall, C. B., Amodu, A., Sharma, D. R., Androga, L. A., & Hawkins, M. A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194697 · Cited by 239
Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: A new paradigm beyond sarcopenia
Ahn, H., Kim, D. W., Ko, Y., Ha, J., Shin, Y. B., Lee, J., Sung, Y. S., & Kim, K. W. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101398 · Cited by 221
Calculating Confidence Intervals for Rates and Ratios
Schoenberg, B. S. (1984) · Neuroepidemiology · doi:10.1159/000110529 · Cited by 218
Asian women have greater abdominal and visceral adiposity than Caucasian women with similar body mass index
Lim, U., Ernst, T. M., Buchthal, S. D., Latch, M., Albright, C. L., Wilkens, L. R., Kolonel, L. N., Murphy, S. P., Chang, L., Novotny, R., et al. (2011) · Nutrition and Diabetes · doi:10.1038/nutd.2011.2 · Cited by 216
Association of sarcopenic obesity with the risk of all-cause mortality among adults over a broad range of different settings: a updated meta-analysis
Zhang, X., Xie, X., Dou, Q., Liu, C., Zhang, W., Yang, Y., Deng, R., & Cheng, A. S. K. (2019) · BMC Geriatrics · doi:10.1186/s12877-019-1195-y · Cited by 209
Self-citation
Stroke-Related Sarcopenia: Specific Characteristics
Scherbakov, N., Sandek, A., & Doehner, W. (2015) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2014.12.007 · Cited by 198
Sarcopenic obesity is closely associated with metabolic syndrome
Lu, C.-W., Yang, K.-C., Chang, H.-H., Lee, L.-T., Chen, C.-Y., & Huang, K.-C. (2013) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2012.02.003 · Cited by 198
Sarcopenia: An Independent Predictor of Mortality in Community-Dwelling Older Korean Men
Kim, J. H., Lim, S. K., Choi, S. H., Kim, K. M., Yoon, J. W., Kim, K. W., Lim, J., Park, K. S., Jang, H. C., & Kritchevsky, S. B. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu050 · Cited by 183
Sarcopenia and sarcopenic obesity and their association with dyslipidemia in Korean elderly men: the 2008–2010 Korea National Health and Nutrition Examination Survey
Baek, S. J., Nam, G. E., Han, K. D., Choi, S. W., Jung, S. W., Bok, A. R., Kim, Y. H., Lee, K. S., Han, B. D., & Kim, D. H. (2014) · Journal of Endocrinological Investigation · doi:10.1007/s40618-013-0011-3 · Cited by 182
Sarcopenic obesity is more closely associated with knee osteoarthritis than is nonsarcopenic obesity: A cross‐sectional study
Lee, S., Kim, T., & Kim, S. (2012) · Arthritis & Rheumatism · doi:10.1002/art.37696 · Cited by 182
Sarcopenic Obesity and Its Temporal Associations With Changes in Bone Mineral Density, Incident Falls, and Fractures in Older Men: The Concord Health and Ageing in Men Project
Scott, D. S., Seibel, M. J., Cumming, R. G., Naganathan, V., Blyth, F., Couteur, D. G. L., Handelsman, D. J., Waite, L. M., & Hirani, V. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3016 · Cited by 180
Sex differences in the prevalence and adverse outcomes of sarcopenia and sarcopenic obesity in community dwelling elderly in East China using the AWGS criteria
Du, Y., Wang, X., Xie, H., Zheng, S., Wu, X., Zhu, X., Zhang, X., Xue, S., Li, H., Hong, W., et al. (2019) · BMC Endocrine Disorders · doi:10.1186/s12902-019-0432-x · Cited by 175
Intramyocellular lipid and impaired myofiber contraction in normal weight and obese older adults
Choi, S. J., Files, D. C., Zhang, T., Wang, Z.-M., Messi, M. L., Gregory, H., Stone, J., Lyles, M. F., Dhar, S., Marsh, A. P., et al. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glv169 · Cited by 171
Sarcopenia, sarcopenic obesity and inflammation: Results from the 1999–2004 National Health and Nutrition Examination Survey
Batsis, J. A., MacKenzie, T. A., Jones, J. D. G., López-Jiménez, F. A., & Bartels, S. J. (2016) · Clinical Nutrition · doi:10.1016/j.clnu.2016.03.028 · Cited by 170
Association of physical activity with sarcopenia and sarcopenic obesity in community-dwelling older adults: the Fourth Korea National Health and Nutrition Examination Survey
Ryu, M., Jo, J., Lee, Y., Chung, Y.-S., Kim, K.-M., & Baek, W.-C. (2013) · Age and Ageing · doi:10.1093/ageing/aft063 · Cited by 168
Self-citation
Obesity paradox in stroke – Myth or reality? A systematic review
Oesch, L., Tatlisumak, T., Arnold, M., & Sarıkaya, H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0171334 · Cited by 162
Sarcopenia as a Determinant of Blood Pressure in Older Koreans: Findings from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2008–2010
Han, K., Park, Y., Kwon, H., Ko, S., Lee, S., Yim, H. W., Lee, W.-C., Park, Y. G., Kim, M. K., & Park, Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086902 · Cited by 161
Oxidative stress is increased in sarcopenia and associated with cardiovascular disease risk in sarcopenic obesity
Bellanti, F., Romano, A. D., Lo Buglio, A., Castriotta, V., Guglielmi, G., Greco, A., Serviddio, G., & Vendemiale, G. (2018) · Maturitas · doi:10.1016/j.maturitas.2017.12.002 · Cited by 158
Sedentary behaviour, physical activity, and sarcopenia among older adults in the TSHA: isotemporal substitution model
Sánchez‐Sánchez, J. L., Mañas, A., García‐García, F. J., Ara, I., Carnicero, J. A. C., Walter, S., & Rodríguez‐Mañas, L. (2019) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12369 · Cited by 154
Diagnosis of sarcopenia by evaluating skeletal muscle mass by adjusted bioimpedance analysis validated with dual-energy X-ray absorptiometry
Cheng, K. Y., Chow, S. K., Hung, V. W., Wong, C. H., Wong, R. M., Tsang, C. S., Kwok, T., & Cheung, W. (2021) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12825 · Cited by 154
Self-citation
Associations of Sarcopenic Obesity and Dynapenic Obesity with Bone Mineral Density and Incident Fractures Over 5–10 Years in Community-Dwelling Older Adults
Scott, D., Chandrasekara, S. D., Laslett, L. L., Cicuttini, F., Ebeling, P. R., & Jones, G. (2016) · Calcified Tissue International · doi:10.1007/s00223-016-0123-9 · Cited by 149
Health-related quality of life and fall risk associated with age-related body composition changes; sarcopenia, obesity and sarcopenic obesity
Öztürk, Z. A., Türkbeyler, İ. H., Abiyev, A., Kul, S., Edizer, B., Yakaryılmaz, F. D., & Soylu, G. (2018) · Internal Medicine Journal · doi:10.1111/imj.13935 · Cited by 147
Associations between measures of sarcopenic obesity and risk of cardiovascular disease and mortality: a cohort study and mendelian randomization analysis using the UK biobank
Farmer, R. E., Mathur, R., Schmidt, A. F., Bhaskaran, K., Fatemifar, G., Eastwood, S. V., Finan, C., Denaxas, S., Smeeth, L., & Chaturvedi, N. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.118.011638 · Cited by 144
Adipose lipid turnover and long-term changes in body weight
Arner, P., Bernard, S., Appelsved, L., Fu, K.-Y., Andersson, D. P., Salehpour, M., Thorell, A., Rydén, M., & Spalding, K. L. (2019) · Nature Medicine · doi:10.1038/s41591-019-0565-5 · Cited by 144
Sarcopenic obesity: how do we treat it?
Bouchonville, M. F., & Villareal, D. T. (2013) · Current Opinion in Endocrinology, Diabetes & Obesity · doi:10.1097/01.med.0000433071.11466.7f · Cited by 141
Prevalence and Associated Factors of Sarcopenia in Singaporean Adults—The Yishun Study
Pang, B. W. J., Wee, S. L., Lau, L. K., Jabbar, K. B. A., Seah, W. T., Ng, D. H. M., Tan, Q. L. L., Chen, K. K., Jagadish, M. U., & Ng, T. P. (2020) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2020.05.029 · Cited by 134
Skeletal muscle transcriptome in healthy aging
Tumasian, R. A., Harish, A., Kundu, G., Yang, J.-H., Ubaida-Mohien, C., Gonzalez-Freire, M., Kaileh, M., Zukley, L. M., Chia, C. W., Lyashkov, A., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22168-2 · Cited by 126
Age-related differences in lower extremity tissue compartments and associations with physical function in older adults
Buford, T. W., Lott, D. J., Marzetti, E., Wohlgemuth, S. E., Vandenborne, K., Pahor, M., Leeuwenburgh, C., & Manini, T. M. (2011) · Experimental Gerontology · doi:10.1016/j.exger.2011.10.001 · Cited by 122
Sarcopenic obesity and risk of new onset depressive symptoms in older adults: English Longitudinal Study of Ageing
Hamer, M., Batty, G. D., & Kivimaki, M. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.124 · Cited by 121
Myosteatosis and myofibrosis: Relationship with aging, inflammation and insulin resistance
Zoico, E., Corzato, F., Bambace, C., Rossi, A. P., Micciolo, R., Cinti, S., Harris, T. B., & Zamboni, M. (2013) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2013.06.001 · Cited by 118
Age-Related Anabolic Resistance of Myofibrillar Protein Synthesis Is Exacerbated in Obese Inactive Individuals
Smeuninx, B., Mckendry, J., Wilson, D., Martin, U., & Breen, L. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00869 · Cited by 118
Low Lean Mass With and Without Obesity, and Mortality: Results From the 1999–2004 National Health and Nutrition Examination Survey
Batsis, J. A., Mackenzie, T. A., Emeny, R. T., Lopez-Jimenez, F., & Bartels, S. J. (2017) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glx002 · Cited by 116
Sarcopenic obesity, weight loss, and mortality: the english longitudinal study of ageing
Hamer, M., & O’Donovan, G. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.152488 · Cited by 110
Exploring the Impact of Obesity on Skeletal Muscle Function in Older Age
Morgan, P. T., Smeuninx, B., & Breen, L. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.569904 · Cited by 108
The obesity paradox is mostly driven by decreased noncardiovascular disease mortality in the oldest old in China: A 20-year prospective cohort study
Lv, Y., Mao, C., Gao, X., Ji, J. S., Kraus, V. B., Yin, Z., Yuan, J., Chen, H., Luo, J., Zhou, J., et al. (2022) · Nature Aging · doi:10.1038/s43587-022-00201-3 · Cited by 102
Racial differences in body fat distribution among reproductive-aged women
Rahman, M., Temple, J. R., Breitkopf, C. R., & Berenson, A. B. (2009) · Metabolism · doi:10.1016/j.metabol.2009.04.017 · Cited by 99
Leptin in Sarcopenic Visceral Obesity: Possible Link between Adipocytes and Myocytes
Kohara, K., Ochi, M., Tabara, Y., Nagai, T., Igase, M., & Miki, T. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024633 · Cited by 99
The association between sarcopenic obesity and depressive symptoms in older Japanese adults
Ishii, S., Chang, C., Tanaka, T., Kuroda, A., Tsuji, T., Akishita, M., & Iijima, K. (2016) · PLOS ONE · doi:10.1371/journal.pone.0162898 · Cited by 95
Muscle quality and muscle fat infiltration in relation to incident mobility disability and gait speed decline: the Age, Gene/Environment Susceptibility-Reykjavik Study
Reinders, I., Murphy, R. A., Koster, A., Brouwer, I. A., Visser, M., Garcia, M. E., Launer, L. J., Siggeirsdottir, K., Eiriksdottir, G., Jonsson, P. V., et al. (2015) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glv016 · Cited by 93
Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects
Bucci, L., Yani, S. L., Fabbri, C., Bijlsma, A. Y., Maier, A. B., Meskers, C. G. M., Narici, M. V., Jones, D. A., McPhee, J. S., Seppet, E. K., et al. (2013) · Biogerontology · doi:10.1007/s10522-013-9428-5 · Cited by 93
Sarcopenia, Obesity and Sarcopenia Obesity in Comparison: Prevalence, Metabolic Profile, and Key Differences: Results from WCHAT Study
Liu, X., Hao, Q., Yue, J., Hou, L., Xia, X., Zhao, W., Zhang, Y., Ge, M., Ge, N., & Dong, B. (2020) · The journal of nutrition health & aging · doi:10.1007/s12603-020-1332-5 · Cited by 88
Mechanical loading stimulates hypertrophy in tissue‐engineered skeletal muscle: Molecular and phenotypic responses
Aguilar‐Agon, K. W., Capel, A. J., Martin, N. R. W., Player, D. J., & Lewis, M. P. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28923 · Cited by 84
Sarcopenic obesity: Myokines as potential diagnostic biomarkers and therapeutic targets?
Guo, A., Li, K., & Xiao, Q. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.111022 · Cited by 83 · cited 1×
“The pathogenetic roles of these biomarkers in SO and SO-related diseases require further investigation to explore whether they are potential therapeutic targets.(131) Simi-”
Background
Increased Plin2 Expression in Human Skeletal Muscle Is Associated with Sarcopenia and Muscle Weakness
Conte, M., Vasuri, F., Trisolino, G., Bellavista, E., Santoro, A., Degiovanni, A., Martucci, E., D’Errico, A., Caporossi, D., Capri, M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073709 · Cited by 83
Association between sarcopenia, sarcopenic obesity, and chronic disease in Korean elderly
Lim, H.-S., Park, Y.-H., Suh, K., Yoo, M. H., Park, H. K., Kim, H. J., Lee, J.-H., & Byun, D.-W. (2018) · Journal of Bone Metabolism · doi:10.11005/jbm.2018.25.3.187 · Cited by 81
Sarcopenia and sarcopenic obesity in comparison: prevalence, metabolic profile, and key differences. A cross-sectional study in Italian hospitalized elderly
Perna, S., Peroni, G., Faliva, M. A., Bartolo, A., Naso, M., Miccono, A., & Rondanelli, M. (2017) · Aging Clinical and Experimental Research · doi:10.1007/s40520-016-0701-8 · Cited by 76
Sarcopenia and sarcopenic obesity classifications and cardiometabolic risks in older women
dos Santos, E. P., Gadelha, A. B., Safons, M. P., Nóbrega, O. T., Oliveira, R. J., & Lima, R. M. (2014) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2014.03.012 · Cited by 69
Phenotype of sarcopenic obesity in older individuals with a history of falling
Huo, Y. R., Suriyaarachchi, P., Gómez, F., Curcio, C., Boersma, D., Gunawardene, P., Demontiero, O., & Duque, G. (2016) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2016.04.003 · Cited by 68
Identification of sarcopenic obesity in postmenopausal women: a cutoff proposal
Oliveira, R. J., Bottaro, M., Júnior, J. T., Farinatti, P. T. V., Bezerra, L. A., & Lima, R. M. (2011) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2011007500135 · Cited by 68
Mid-adulthood cardiometabolic risk factor profiles of sarcopenic obesity
Ma, J., Hwang, S., McMahon, G. M., Curhan, G. C., Mclean, R. R., Murabito, J. M., & Fox, C. S. (2016) · Obesity · doi:10.1002/oby.21356 · Cited by 68
Association of Sarcopenic Obesity with Higher Serum High-Sensitivity C-Reactive Protein Levels in Chinese Older Males - A Community-Based Study (Taichung Community Health Study-Elderly, TCHS-E)
Yang, C., Li, C.-I., Lin, C., Liu, C.-S., Lin, C., Lin, C., & Lin, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132908 · Cited by 65
Self-citation
Adipokines, Myokines, and Cardiokines: The Role of Nutritional Interventions
Senesi, P., Luzi, L., & Terruzzi, I. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218372 · Cited by 65
Implication of Sarcopenia and Sarcopenic Obesity on Lung Function in Healthy Elderly: Using Korean National Health and Nutrition Examination Survey
Moon, J. H., Kong, M. H., & Kim, H. J. (2015) · Journal of Korean Medical Science · doi:10.3346/jkms.2015.30.11.1682 · Cited by 64
The impacts of sarcopenia and obesity on physical performance in the elderly
Chang, C.-I., Huang, K., Chan, D., Wu, C., Lin, C., Hsiung, C. A., Hsu, C.-C., & Chen, C. (2014) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2014.08.003 · Cited by 63
Relationship between sarcopenic obesity‐related phenotypes and inflammatory markers in postmenopausal women
Dutra, M. T., Avelar, B. P., Souza, V. C., Bottaro, M., Oliveira, R. J., Nóbrega, O. T., & Moreno Lima, R. (2017) · Clinical Physiology and Functional Imaging · doi:10.1111/cpf.12287 · Cited by 63
Effect of sarcopenic obesity on deterioration of physical function in the elderly
Kong, H. H., Won, C. W., & Kim, W. D. (2020) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2020.104065 · Cited by 63
Inter-muscular adipose tissue is associated with adipose tissue inflammation and poorer functional performance in central adiposity
Lim, J. P., Chong, M. S., Tay, L. B. G., Yang, Y. X., Leung, B. P. L., Yeo, A., Yew, S., Tan, C. H., & Lim, W. S. (2018) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2018.11.006 · Cited by 62
Incident Impaired Cognitive Function in Sarcopenic Obesity: Data From the National Health and Aging Trends Survey
Batsis, J. A., Haudenschild, C., Roth, R. M., Gooding, T., Roderka, M. N., Masterson, T. D., Brand, J., Lohman, M. C., & MacKenzie, T. A. (2020) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2020.09.008 · Cited by 61
The most effective factors to offset sarcopenia and obesity in the older Korean: Physical activity, vitamin D, and protein intake
Oh, C., Jeon, B. H., Reid Storm, S. N., Jho, S., & No, J.-K. (2017) · Nutrition · doi:10.1016/j.nut.2016.06.004 · Cited by 60
Sarcopenia in the aging high-fat fed rat: a pilot study for modeling sarcopenic obesity in rodents
Bollheimer, L. C., Buettner, R., Pongratz, G., Brunner-Ploss, R., Hechtl, C., Banas, M., Singler, K., Hamer, O. W., Stroszczynski, C., Sieber, C. C., et al. (2012) · Biogerontology · doi:10.1007/s10522-012-9405-4 · Cited by 57
Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice
Lee, H., Ha, T. Y., Jung, C. H., Nirmala, F. S., Park, S., Huh, Y. H., & Ahn, J. (2021) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12794 · Cited by 55
Abdominal Obesity and Low Skeletal Muscle Mass Jointly Predict Total Mortality and Cardiovascular Mortality in an Elderly Asian Population
Chuang, S., Hsu, Y., Chen, R. C.-Y., Liu, W., & Pan, W. (2015) · The Journals of Gerontology Series A · doi:10.1093/gerona/glv192 · Cited by 54
Periodontal disease and the risk of Alzheimer's disease and mild cognitive impairment: a systematic review and meta‐analysis
Hu, X. Y., Zhang, J., Qiu, Y., & Liu, Z. (2021) · Psychogeriatrics · doi:10.1111/psyg.12743 · Cited by 52
Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin‐proteasome and autophagic/lysosomal proteolytic flux
Bollinger, L. M., Powell, J. J. S., Houmard, J. A., Witczak, C. A., & Brault, J. J. (2015) · Obesity · doi:10.1002/oby.21081 · Cited by 51
Association of body composition with sarcopenic obesity in elderly women
Silva, A. D. O., Karnikowski, M. G. D. O., Funghetto, S. S., Prestes, J., Lima, R. M., Stival, de Souza, C., & Navalta (2013) · International Journal of General Medicine · doi:10.2147/ijgm.s36279 · Cited by 48
The relationship between all-cause mortality sarcopenia and sarcopenic obesity among hospitalized older people
Atmış, V., Yalçın, A., Sılay, K., kandil, S. U., Bahşi, R., Turgut, T., Sürmeli, D. M., Öztorun, H. S., Yaman, S., Coşarderelioğlu, Ç., et al. (2019) · Aging Clinical and Experimental Research · doi:10.1007/s40520-019-01277-5 · Cited by 48
Age-Related Skeletal Muscle Dysfunction Is Aggravated by Obesity: An Investigation of Contractile Function, Implications and Treatment
Tallis, J. A., Shelley, S. P., Degens, H., & Hill, C. (2021) · Biomolecules · doi:10.3390/biom11030372 · Cited by 46
Worsening disability and hospitalization risk in sarcopenic obese and dynapenic abdominal obese: A 5.5 years follow-up study in elderly men and women
Rossi, A. P., Urbani, S., Fantin, F., Nori, N., Brandimarte, P., Martini, A., Zoico, E., Mazzali, G., Babbanini, A., Muollo, V., et al. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00314 · Cited by 42 · cited 1×
“001) compared with healthy control.(62) Patients with sarcopenia had increased risk of comorbidities of cancer (OR 1.”
Result
Intramuscular Adipose Tissue and the Functional Components of Sarcopenia in Hospitalized Geriatric Patients
Perkisas, S., Cock, A. D., Verhoeven, V., & Vandewoude, M. F. J. (2017) · Geriatrics · doi:10.3390/geriatrics2010011 · Cited by 42
Validation of a description of sarcopenic obesity defined as excess adiposity and low lean mass relative to adiposity
Baker, J. F., Harris, T. B., Rapoport, A., Ziolkowski, S., Leonard, M. B., Long, J., Zemel, B. S., & Weber, D. R. (2020) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12613 · Cited by 39
Muscle mass is associated with incident fracture in postmenopausal women: The OFELY study
Sornay‐Rendu, E., Duboeuf, F., Boutroy, S., & Chapurlat, R. D. (2016) · Bone · doi:10.1016/j.bone.2016.10.024 · Cited by 38
Influence of skeletal muscle mass and fat mass on the metabolic and inflammatory profile in sarcopenic and non-sarcopenic overfat elderly
Rossi, F. E., Lira, F. S., Silva, B. S. D. A., Freire, A. P. C. F., Ramos, E. M. C., & Gobbo, L. A. (2018) · Aging Clinical and Experimental Research · doi:10.1007/s40520-018-1029-3 · Cited by 38
Associations between Muscle Strength with Different Measures of Obesity and Lipid Profiles in Men and Women: Results from RaNCD Cohort Study
Pasdar, Y., Darbandi, M., Mirtaher, E., Rezaeian, S., Najafi, F., & Hamzeh, B. (2019) · Clinical Nutrition Research · doi:10.7762/cnr.2019.8.2.148 · Cited by 38
Obesity, sarcopenia, sarcopenic obesity and reduced mobility in Brazilian older people aged 80 years and over
dos Santos, V. R., Gomes, I. C., Bueno, D. R., Christófaro, D. G. D., Júnior, I. F. F., & Gobbo, L. A. (2017) · Einstein (São Paulo) · doi:10.1590/s1679-45082017ao4058 · Cited by 36
Muscle Quality As a Potential Explanation of the Metabolically Healthy but Obese and Sarcopenic Obese Paradoxes
Barbat‐Artigas, S., Filion, M., Plouffe, S., & Aubertin‐Leheudre, M. (2011) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2011.0092 · Cited by 35
Differences in body composition and physical function related to pure sarcopenia and sarcopenic obesity: A study of community‐dwelling older adults in Japan
Kera, T., Kawai, H., Hirano, H., Kojima, M., Fujiwara, Y., Ihara, K., & Obuchi, S. P. (2017) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.13119 · Cited by 35
Prognostic value of sarcopenic obesity estimated by computed tomography in patients with cardiovascular disease and undergoing surgery
Yamashita, M., Kamiya, K., Matsunaga, A., Kitamura, T., Hamazaki, N., Matsuzawa, R., Nozaki, K., Tanaka, S., Nakamura, T., Maekawa, E., et al. (2019) · Journal of Cardiology · doi:10.1016/j.jjcc.2019.02.010 · Cited by 35
The Relationship Between Intermuscular Fat and Physical Performance Is Moderated by Muscle Area in Older Adults
Farsijani, S., Santanasto, A. J., Miljkovic, I., Boudreau, R. M., Goodpaster, B. H., Kritchevsky, S. B., & Newman, A. B. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa161 · Cited by 33
Sarcopenic obesity and its association with respiratory disease incidence and mortality
Petermann-Rocha, F. E., Yang, S., Gray, S. R., Pell, J. P., Celis-Morales, C. A., & Ho, F. K. W. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.03.006 · Cited by 32
Muscle‐specific Perilipin2 down‐regulation affects lipid metabolism and induces myofiber hypertrophy
Conte, M., Armani, A., Conte, G., Serra, A., Franceschi, C., Mele, M., Sandri, M., & Salvioli, S. (2019) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12355 · Cited by 30
The relation between mortality, intramuscular adipose tissue and sarcopenia in hospitalized geriatric patients
Perkisas, S., Lamers, S., Degerickx, R., Mieghem, E. V., Vandewoude, M., Verhoeven, V., & Cock, A. D. (2018) · European Geriatric Medicine · doi:10.1007/s41999-018-0110-y · Cited by 28
Higher Serum Leptin Levels are Associated with a Reduced Risk of Sarcopenia but a Higher Risk of Dynapenia Among Older Adults
Kao, T., Peng, T., Chen, W., Chi, Y., Chen, C., & Yang, W. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s335694 · Cited by 25
Comparisons of Muscle Quality and Muscle Growth Factor Between Sarcopenic and Non-Sarcopenic Older Women
Seo, M.-W., Jung, S.-W., Kim, S.-W., Jung, H. C., Kim, D., & Song, J.-K. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186581 · Cited by 23
Thigh muscle attenuation measured by computed tomography was associated with the risk of low bone density in community‐dwelling elderly population
Kim, J. H., Choi, S. H., Lim, S. K., Lim, J., Kim, K. W., Park, K. S., Shin, C. S., & Jang, H. C. (2012) · Clinical Endocrinology · doi:10.1111/cen.12016 · Cited by 21
Dual effects of obesity on satellite cells and muscle regeneration
Geiger, A. E., Daughtry, M. R., Yen, C., Kirkpatrick, L. T., Shi, H., & Gerrard, D. E. (2020) · Physiological Reports · doi:10.14814/phy2.14511 · Cited by 21
The Influence of Age and Obesity-Altered Muscle Tissue Composition on Muscular Dimensional Changes: Impact on Strength and Function
Giuliani, H. K., Shea, N. W., Gerstner, G. R., Mota, J. A., Blackburn, J. T., & Ryan, E. D. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa206 · Cited by 18
Examining the association between muscle mass, muscle function, and fat indexes in an elderly population
Chao, Y., Chen, W., Peng, T., Wu, L., Liaw, F., & Kao, T. (2020) · Nutrition · doi:10.1016/j.nut.2020.111071 · Cited by 14
Relationship between thigh intermuscular adipose tissue accumulation and number of metabolic syndrome risk factors in middle-aged and older Japanese adults
Bang, E., Tanabe, K., Yokoyama, N., Chijiki, S., & Kuno, S. (2016) · Experimental Gerontology · doi:10.1016/j.exger.2016.03.010 · Cited by 13
Predicting Future Years of Life, Health, and Functional Ability
Diehr, P. H., Diehr, M. C., Arnold, A. M., Yee, L. M., Odden, M. C., Hirsch, C. H., Thielke, S. M., Psaty, B. M., Johnson, W. C., Kizer, J. R., et al. (2015) · Gerontology and Geriatric Medicine · doi:10.1177/2333721415605989 · Cited by 13
Balancing Weight Loss and Sarcopenia in Elderly Patients With Peripheral Artery Disease
Kokkinidis, D. G., Armstrong, E. J., & Giri, J. (2019) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.119.013200 · Cited by 12
Elevated serum leptin levels are associated with low muscle strength and muscle quality in male patients undergoing chronic hemodialysis
Hsu, B., Wang, C., Lai, Y.-H., Kuo, C., & Lin, Y. (2020) · Tzu Chi Medical Journal · doi:10.4103/tcmj.tcmj_20_20 · Cited by 9
Low muscle mass and large portosystemic shunt in “one-stop shop” CT exponentially increases risk for HE and mortality
Abu-Omar, J., Faron, A., Chang, J., Böhling, N., Sprinkart, A. M., Meyer, C. H., Strassburg, C. P., Jansen, C., Trebicka, J., Luetkens, J. A., et al. (2020) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0039-3402156 · Cited by 1
Effect of Different Exercise and Nutrition in Reducing Risk of Obesity: Systematic Review
Worku, M. (2021) · International Journal of Sport Exercise and Health Research · doi:10.31254/sportmed.3106 · Cited by 1

Flagged first, then by citations

2 of the 133 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

Lim JP, 2015, Monocyte chemoattractant protein‐1: a proinflammatory cytokine elevated in sarcopenic obesity, Clin Interv Aging, 10, 605

Sorted by citations

Epidemiology of sarcopenia: Prevalence, risk factors, and consequences
Yuan, S., & Larsson, S. C. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155533 · Cited by 1,114
Sarcopenic obesity in older adults: a clinical overview
Prado, C. M., Batsis, J. A., Donini, L. M., Gonzalez, M. C., & Siervo, M. (2024) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00943-z · Cited by 355
Advantages and Limitations of the Body Mass Index (BMI) to Assess Adult Obesity
Wu, Y., Li, D., & Vermund, S. H. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21060757 · Cited by 332
“Among adults, BMI has been used to assess overweight status independent of age or sex [28], though its cut-offs for the elderly are debated [30].”
Background
A focus shift from sarcopenia to muscle health in the Asian Working Group for Sarcopenia 2025 Consensus Update
Chen, L., Hsiao, F., Akishita, M., Assantachai, P., Lee, W., Lim, W. S., Muangpaisan, W., Kim, M., Merchant, R. A., Peng, L., et al. (2025) · Nature Aging · doi:10.1038/s43587-025-01004-y · Cited by 339
Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management
Wei, S., Nguyen, T. T., Zhang, Y., Ryu, D., & Gariani, K. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1185221 · Cited by 291

See all 247

Authors: Liu, C., Wong, P. Y., Chung, Y. L., Chow, S. K., Cheung, W. H., Law, S. W., Chan, J. C. N., & Wong, R. M. Y.
Affiliations: Chinese University of Hong Kong (HK)
Corresponding author: Wong, Ronald Man Yeung
ORCID: Liu, Chaoran
Wong, Pui Yan
Chung, Yik Lok
Chow, Simon Kwoon‐Ho
Cheung, Wing Hoi
Law, Sheung Wai
Chan, Juliana Chung Ngor
Wong, Ronald Man Yeung
Venue: Obesity Reviews
Publisher: Wiley
Published: 2022-11-28
Volume: 24
Issue: 2
Pages: e13534-e13534
ISSN: 1467-7881 (ISSN-L)
1467-789X
DOI: 10.1111/obr.13534
OpenAlex: W4310209091
Cited by: 247
References: 133
Citations by year: 2026: 61 · 2025: 92 · 2024: 70 · 2023: 24
FWCI: 6.40
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Obesity Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Keywords: sarcopenic obesity, obesity paradox, sarcopenia, aging, older adults, all-cause mortality, cardiovascular disease, cognitive impairment, functional limitations, muscle mass, muscle strength, body composition, prevalence
MeSH terms: Aged, Aging, Body Composition, Cardiovascular Diseases, Female, Humans, Male, Obesity, Sarcopenia

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Deciphering the “obesity paradox” in the elderly: A systematic review and meta‐analysis of sarcopenic obesity

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks