The DOI matches its Crossref record; 316 of the 316 references it cites were found in a registry or an index.
ATP-Binding Cassette Transporter A1: A Cell Cholesterol Exporter That Protects Against Cardiovascular Disease
Abstract
Blood high-density lipoprotein (HDL) levels are inversely related to risk for cardiovascular disease, implying that factors associated with HDL metabolism are atheroprotective. One of these factors is ATP-binding cassette transporter A1 (ABCA1), a cell membrane protein that mediates the transport of cholesterol, phospholipids, and other metabolites from cells to lipid-depleted HDL apolipoproteins. ABCA1 transcription is highly induced by sterols, a major substrate for cellular export, and its expression and activity are regulated posttranscriptionally by diverse processes. Liver ABCA1 initiates formation of HDL particles, and macrophage ABCA1 protects arteries from developing atherosclerotic lesions. ABCA1 mutations can cause a severe HDL deficiency syndrome characterized by cholesterol deposition in tissue macrophages and prevalent atherosclerosis. Genetic manipulations of ABCA1 expression in mice also affect plasma HDL levels and atherogenesis. Metabolites elevated in individuals with the metabolic syndrome and diabetes destabilize ABCA1 protein and decrease cholesterol export from macrophages. Moreover, oxidative modifications of HDL found in patients with cardiovascular disease reduce the ability of apolipoproteins to remove cellular cholesterol by the ABCA1 pathway. These observations raise the possibility that an impaired ABCA1 pathway contributes to the enhanced atherogenesis associated with common inflammatory and metabolic disorders. The ABCA1 pathway has therefore become an important new therapeutic target for treating cardiovascular disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Chang, G., & Roth, C. B. (2001) · Science · doi:10.1126/science.293.5536.1793 · Cited by 619
RetractedChang, G. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00587-4 · Cited by 259
RetractedNitric oxide: physiology, pathophysiology, and pharmacology.
Moncada, S., Palmer, R. M., & Higgs, E. A. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06663-3 · Cited by 15,525
The Metabolic and Molecular Bases of Inherited Disease
Scriver, R. C. (1995) · Medical Entomology and Zoology · Cited by 12,101
A Receptor-Mediated Pathway for Cholesterol Homeostasis
Brown, M. S., & Goldstein, J. L. (1986) · Science · doi:10.1126/science.3513311 · Cited by 5,703
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
Mahley, R. W. (1988) · Science · doi:10.1126/science.3283935 · Cited by 4,028
Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., & Kliewer, S. A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.12953 · Cited by 3,625
Role of oxidized low density lipoprotein in atherogenesis.
Witztum, J. L., & Steinberg, D. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115499 · Cited by 2,675
Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications
Flier, J. S., Underhill, L. H., Brownlee, M., Cerami, A., & Vlassara, H. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805193182007 · Cited by 2,511
Takai, Y., Sasaki, T., & Matozaki, T. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.153 · Cited by 2,475
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.
Baynes, J. W., & Thorpe, S. R. (1999) · Diabetes · doi:10.2337/diabetes.48.1.1 · Cited by 2,441
The plasma lecithin:cholesterol acyltransferase reaction
Glomset, J. A. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43114-1 · Cited by 2,405
Anderson, R. G. W. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.199 · Cited by 1,942
Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ
Nagy, L., Tontonoz, P., Alvarez, J. G. A., Chen, H., & Evans, R. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81574-3 · Cited by 1,860
PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL
Tontonoz, P., Nagy, L., Alvarez, J. G. A., Thomazy, V. A., & Evans, R. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81575-5 · Cited by 1,797
Statins and the risk of dementia
Jick, H., Zornberg, G., Jick, S., Seshadri, S., & Drachman, D. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03155-x · Cited by 1,759
Nissen, S. E., Tsunoda, T., Tuzcu, E. M., Schoenhagen, P., Cooper, C. J., Yasin, M., Eaton, G. M., Lauer, M. A., Sheldon, W. S., Grines, C. L., et al. (2003) · JAMA · doi:10.1001/jama.290.17.2292 · Cited by 1,707
Repa, J. J., Liang, G., Ou, J., Bashmakov, Y., Lobaccaro, J.-M. A., Shimomura, I., Shan, B., Brown, M. S., Goldstein, J. L., & Mangelsdorf, D. J. (2000) · Genes & Development · doi:10.1101/gad.844900 · Cited by 1,692
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L.-H., Roomp, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O. F., et al. (1999) · Nature Genetics · doi:10.1038/11905 · Cited by 1,687
Berge, K. E., Tian, H., Graf, G. A., Yu, L., Grishin, N. V., Schultz, J., Kwiterovich, P., Shan, B., Barnes, R., & Hobbs, H. H. (2000) · Science · doi:10.1126/science.290.5497.1771 · Cited by 1,648
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
Bodzioch, M., Orsó, E., Klucken, J., Langmann, T., Böttcher, A., Diederich, W., Drobnik, W., Barlage, S., Büchler, C., Porsch-Özcürümez, M., et al. (1999) · Nature Genetics · doi:10.1038/11914 · Cited by 1,512
Role of LXRs in control of lipogenesis
Schultz, J. R., Tu, H., Luk, A., Repa, J. J., Medina, J. C., Li, L., Schwendner, S., Wang, S., Thoolen, M., Mangelsdorf, D. J., et al. (2000) · Genes & Development · doi:10.1101/gad.850400 · Cited by 1,499
Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
Eiserich, J. P., Hristova, M., Cross, C. E., Jones, A. D., Freeman, B. A., Halliwell, B., & van der Vliet, A. (1998) · Nature · doi:10.1038/34923 · Cited by 1,496
Molecular physiology of reverse cholesterol transport.
Fielding, C. J., & Fielding, P. E. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39898-9 · Cited by 1,448
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J.-C., Deleuze, J.-F., Brewer, H. B., Duverger, N., Denèfle, P., et al. (1999) · Nature Genetics · doi:10.1038/11921 · Cited by 1,433
Antioxidants and Atherosclerotic Heart Disease
Diaz, M. N., Frei, B., Vita, J. A., & Keaney, J. F. (1997) · New England Journal of Medicine · doi:10.1056/nejm199708073370607 · Cited by 1,353
A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis
Chawla, A., Boisvert, W. A., Lee, C.-H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., et al. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00164-2 · Cited by 1,347
The human ATP-binding cassette (ABC) transporter superfamily
Dean, M., Hamon, Y., & Chimini, G. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31588-1 · Cited by 1,302
Regulation of Absorption and ABC1-Mediated Efflux of Cholesterol by RXR Heterodimers
Repa, J. J., Turley, S. D., Lobaccaro, J.-M. A., Medina, J., Li, L., Lustig, K., Shan, B., Heyman, R. A., Dietschy, J. M., & Mangelsdorf, D. J. (2000) · Science · doi:10.1126/science.289.5484.1524 · Cited by 1,301
Wolff, S. P., & Dean, R. T. (1987) · Biochemical Journal · doi:10.1042/bj2450243 · Cited by 1,271
Daugherty, A., Dunn, J. L., Rateri, D. L., & Heinecke, J. W. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117342 · Cited by 1,269
Self-citationFormation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
Thornalley, P. J., LANGBORG, A., & Minhas, H. S. (1999) · Biochemical Journal · doi:10.1042/0264-6021:3440109 · Cited by 1,243
Protein kinase CK2: structure, regulation and role in cellular decisions of life and death
LITCHFIELD, D. W. (2003) · Biochemical Journal · doi:10.1042/bj20021469 · Cited by 1,233
Chinetti, G., Lestavel, S., Bocher, V., Remaley, A. T., Neve, B., Torra, I. P., Teissier, E., Minnich, A., Jaye, M., Duverger, N., et al. (2001) · Nature Medicine · doi:10.1038/83348 · Cited by 1,170
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
Brown, M. S., & Goldstein, J. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11041 · Cited by 1,134
Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol
Cohen, J. C., Kiss, R. S., Pertsemlidis, A., Marcel, Y. L., McPherson, R., & Hobbs, H. H. (2004) · Science · doi:10.1126/science.1099870 · Cited by 1,108
Wang, N., Lan, D., Chen, W., Matsuura, F., & Tall, A. R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403506101 · Cited by 1,061
Brain Cholesterol: Long Secret Life Behind a Barrier
Björkhem, I., & Meaney, S. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000120374.59826.1b · Cited by 1,044
Kim, E., Niethammer, M., Rothschild, A., Nung Jan, Y., & Sheng, M. (1995) · Nature · doi:10.1038/378085a0 · Cited by 1,000
Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI
Rubin, E. M., Krauss, R. M., Spangler, E. A., Verstuyft, J. G., & Clift, S. M. (1991) · Nature · doi:10.1038/353265a0 · Cited by 986
Sterol-dependent Transactivation of theABC1 Promoter by the Liver X Receptor/Retinoid X Receptor
Costet, P., Luo, Y., Wang, N., & Tall, A. R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003337200 · Cited by 979
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
Joseph, S. B., McKilligin, E., Pei, L., Watson, M. A., Collins, A. R., Laffitte, B. A., Chen, M., Noh, G., Goodman, J., Hagger, G. N., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.112059299 · Cited by 947
Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ
Janowski, B. A., Grogan, M. J., Jones, S. A., Wisely, G. B., Kliewer, S. A., Corey, E. J., & Mangelsdorf, D. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.1.266 · Cited by 942
Cholesterol metabolism in the brain
Dietschy, J. M., & Turley, S. D. (2001) · Current Opinion in Lipidology · doi:10.1097/00041433-200104000-00003 · Cited by 906
Segrest, J., Jones, M., De Loof, H., Brouillette, C., Venkatachalapathi, Y., & Anantharamaiah, G. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41536-6 · Cited by 866
Repa, J. J., Berge, K. E., Pomajzl, C., Richardson, J. A., Hobbs, H., & Mangelsdorf, D. J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109927200 · Cited by 852
Li, A. C., Brown, K. K., Silvestre, M. J., Willson, T. M., Palinski, W., & Glass, C. K. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10370 · Cited by 833
High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein
Parthasarathy, S., Barnett, J., & Fong, L. G. (1990) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(90)90314-n · Cited by 827
Zheng, L., Nukuna, B., Brennan, M.-L., Sun, M., Goormastic, M., Settle, M., Schmitt, D., Fu, X., Thomson, L., Fox, P. L., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200421109 · Cited by 737
Lawn, R. M., Wade, D. P., Garvin, M. R., Wang, X., Schwartz, K., Porter, J. G., Seilhamer, J. J., Vaughan, A. M., & Oram, J. F. (1999) · Journal of Clinical Investigation · doi:10.1172/jci8119 · Cited by 724
Self-citationLXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
Laffitte, B. A., Repa, J. J., Joseph, S. B., Wilpitz, D. C., Kast, H. R., Mangelsdorf, D. J., & Tontonoz, P. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.507 · Cited by 683
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption
Lee, M.-H., Lu, K., Hazard, S., Yu, H., Shulenin, S., Hidaka, H., Kojima, H., Allikmets, R., Sakuma, N., Pegoraro, R., et al. (2001) · Nature Genetics · doi:10.1038/83799 · Cited by 682
Liver X Receptor Signaling Pathways in Cardiovascular Disease
Tontonoz, P., & Mangelsdorf, D. J. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0061 · Cited by 633
Glomb, M. A., & Monnier, V. M. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.17.10017 · Cited by 576
27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells
Fu, X., Menke, J. G., Chen, Y., Zhou, G., MacNaul, K. L., Wright, S. D., Sparrow, C. P., & Lund, E. G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105805200 · Cited by 572
McNeish, J., Aiello, R. J., Guyot, D., Turi, T., Gabel, C., Aldinger, C., Hoppe, K. L., Roach, M. L., Royer, L. J., de Wet, J., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4245 · Cited by 537
Oram, J. F., Lawn, R. M., Garvin, M. R., & Wade, D. P. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006738200 · Cited by 536
Self-citationABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.
Hamon, Y., Broccardo, C., Chambenoit, O., Luciani, M.-F., Toti, F., Chaslin, S., Freyssinet, J.-M., Devaux, P. F., McNeish, J., Marguet, D., et al. (2000) · Nature Cell Biology · doi:10.1038/35017029 · Cited by 529
Osborne, T. F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.r000017200 · Cited by 521
Krieger, M. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.523 · Cited by 519
Takai, Y., Kaibuchi, K., Kikuchi, A., & Kawata, M. (1992) · International Review of Cytology · doi:10.1016/s0074-7696(08)61861-6 · Cited by 516
Lewis, P. M., Dunn, M. P., McMahon, J. A., Logan, M., Martin, J. F., St-Jacques, B., & McMahon, A. P. (2001) · Cell · doi:10.1016/s0092-8674(01)00369-5 · Cited by 513
Cell cholesterol efflux: integration of old and new observations provides new insights
Rothblat, G. H., de la Llera-Moya, M., Atger, V., Kellner-Weibel, G., Williams, D. L., & Phillips, M. C. (1999) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32113-1 · Cited by 503
Biological selectivity and functional aspects of protein tyrosine nitration
Ischiropoulos, H. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00814-3 · Cited by 500
Heinecke, J. W., Li, W., Daehnke, H. L., & Goldstein, J. A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53581-x · Cited by 485
Self-citationATP-binding Cassette Transporter A1 (ABCA1) Functions as a Cholesterol Efflux Regulatory Protein
Wang, N., Silver, D. L., Thiele, C., & Tall, A. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102348200 · Cited by 482
Ou, J., Tu, H., Shan, B., Luk, A., DeBose-Boyd, R. A., Bashmakov, Y., Goldstein, J. L., & Brown, M. S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111138698 · Cited by 480
ABCA1: the gatekeeper for eliminating excess tissue cholesterol
Oram, J. F., & Lawn, R. M. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31566-2 · Cited by 480
Self-citationOrsó, E., Broccardo, C., Kaminski, W. E., Böttcher, A., Liebisch, G., Drobnik, W., Götz, A., Chambenoit, O., Diederich, W., Langmann, T., et al. (2000) · Nature Genetics · doi:10.1038/72869 · Cited by 475
Wahrle, S. E., Jiang, H., Parsadanian, M., Legleiter, J., Han, X., Fryer, J. D., Kowalewski, T., & Holtzman, D. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407963200 · Cited by 474
Heinecke, J. W. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(98)00173-7 · Cited by 466
Self-citationBergt, C., Pennathur, S., Fu, X., Byun, J., O'Brien, K., McDonald, T. O., Singh, P., Anantharamaiah, G. M., Chait, A., Brunzell, J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405292101 · Cited by 454
Self-citationFormation of Nitrating and Chlorinating Species by Reaction of Nitrite with Hypochlorous Acid
Eiserich, J. P., Cross, C. E., Jones, A. D., Halliwell, B., & van der Vliet, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.32.19199 · Cited by 447
Francis, G. A., Knopp, R. H., & Oram, J. F. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118082 · Cited by 424
Self-citationGeorge Lyman Duff Memorial Lecture. Atherogenesis in diabetes.
Bierman, E. L. (1992) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.12.6.647 · Cited by 413
Role of Monocytes in Atherogenesis
ØSTERUD, B., & BJØRKLID, E. (2003) · Physiological Reviews · doi:10.1152/physrev.00005.2003 · Cited by 412
ABC1 Gene Expression and ApoA-I-Mediated Cholesterol Efflux Are Regulated by LXR
Schwartz, K., Lawn, R. M., & Wade, D. P. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3243 · Cited by 410
Navab, M., Anantharamaiah, G. M., Hama, S., Garber, D. W., Chaddha, M., Hough, G., Lallone, R., & Fogelman, A. M. (2002) · Circulation · doi:10.1161/hc0302.103711 · Cited by 401
Jiang, X.-C., Bruce, C., Mar, J., Lin, M., Ji, Y., Francone, O. L., & Tall, A. R. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5578 · Cited by 394
Increased Atherosclerosis in Hyperlipidemic Mice With Inactivation of ABCA1 in Macrophages
Aiello, R. J., Brees, D., Bourassa, P.-A., Royer, L., Lindsey, S., Coskran, T., Haghpassand, M., & Francone, O. L. (2002) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000014804.35824.da · Cited by 390
Deficiency of ABCA1 Impairs Apolipoprotein E Metabolism in Brain
Hirsch-Reinshagen, V., Zhou, S., Burgess, B. L., Bernier, L., McIsaac, S. A., Chan, J. Y., Tansley, G. H., Cohn, J. S., Hayden, M. R., & Wellington, C. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407962200 · Cited by 385
Shah, P. K., Yano, J., Reyes, O., Chyu, K.-Y., Kaul, S., Bisgaier, C. L., Drake, S., & Cercek, B. (2001) · Circulation · doi:10.1161/hc2501.092494 · Cited by 381
Neufeld, E. B., Wastney, M., Patel, S., Suresh, S., Cooney, A. M., Dwyer, N. K., Roff, C. F., Ohno, K., Morris, J. A., Carstea, E. D., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.14.9627 · Cited by 373
Leeuwenburgh, C., Rasmussen, J. E., Hsu, F. F., Mueller, D. M., Pennathur, S., & Heinecke, J. W. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3520 · Cited by 361
Self-citationAtherosclerosis in Transgenic Mice Overexpressing Apolipoprotein A-II
Warden, C. H., Hedrick, C. C., Qiao, J.-H., Castellani, L. W., & Lusis, A. J. (1993) · Science · doi:10.1126/science.8332912 · Cited by 360
Regression of Atherosclerosis Induced by Liver-Directed Gene Transfer of Apolipoprotein A-I in Mice
Tangirala, R. K., Tsukamoto, K., Chun, S. H., Usher, D., Puré, E., & Rader, D. J. (1999) · Circulation · doi:10.1161/01.cir.100.17.1816 · Cited by 358
Lu, K., Lee, M.-H., Hazard, S., Brooks-Wilson, A., Hidaka, H., Kojima, H., Ose, L., Stalenhoef, A. F. H., Mietinnen, T., Bjorkhem, I., et al. (2001) · The American Journal of Human Genetics · doi:10.1086/321294 · Cited by 355
Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.
Heinecke, J. W., Li, W., Francis, G. A., & Goldstein, J. A. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116531 · Cited by 354
Self-citationAnderson, M. M., Requena, J. R., Crowley, J. R., Thorpe, S. R., & Heinecke, J. W. (1999) · Journal of Clinical Investigation · doi:10.1172/jci3042 · Cited by 349
Self-citationLeukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues
Van Eck, M., Bos, I. S. T., Kaminski, W. E., Orsó, E., Rothe, G., Twisk, J., Böttcher, A., Van Amersfoort, E. S., Christiansen-Weber, T. A., Fung-Leung, W.-P., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092327399 · Cited by 348
Rosenberg, M. F., Callaghan, R., Ford, R. C., & Higgins, C. F. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.16.10685 · Cited by 345
Human plasma phospholipid transfer protein causes high density lipoprotein conversion.
Jauhiainen, M., Metso, J., Pahlman, R., Blomqvist, S., van Tol, A., & Ehnholm, C. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53575-4 · Cited by 342
Apolipoprotein-mediated removal of cellular cholesterol and phospholipids
Oram, J. F., & Yokoyama, S. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37453-8 · Cited by 341
Self-citationCellular Localization and Trafficking of the Human ABCA1 Transporter
Neufeld, E. B., Remaley, A. T., Demosky, S. J., Stonik, J. A., Cooney, A. M., Comly, M., Dwyer, N. K., Zhang, M., Blanchette-Mackie, J., Santamarina-Fojo, S., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103264200 · Cited by 331
Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils
Domigan, N. M., Charlton, T. S., Duncan, M. W., Winterbourn, C. C., & Kettle, A. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.28.16542 · Cited by 329
Apolipoprotein Specificity for Lipid Efflux by the Human ABCAI Transporter
Remaley, A. T., Stonik, J. A., Demosky, S. J., Neufeld, E. B., Bocharov, A. V., Vishnyakova, T. G., Eggerman, T. L., Patterson, A. P., Duverger, N. J., Santamarina-Fojo, S., et al. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.4219 · Cited by 326
Oxidation of High Density Lipoproteins
Garner, B., Waldeck, A. R., Witting, P. K., Rye, K.-A., & Stocker, R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.11.6088 · Cited by 319
Autoregulation of the Human Liver X Receptor α Promoter
Laffitte, B. A., Joseph, S. B., Walczak, R., Pei, L., Wilpitz, D. C., Collins, J. L., & Tontonoz, P. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.22.7558-7568.2001 · Cited by 315
Clee, S. M., Kastelein, J. J. P., van Dam, M., Marcil, M., Roomp, K., Zwarts, K. Y., Collins, J. A., Roelants, R., Tamasawa, N., Stulc, T., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10727 · Cited by 314
Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I
Rye, K.-A., & Barter, P. J. (2004) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000104029.74961.f5 · Cited by 309
Graf, G. A., Li, W.-P., Gerard, R. D., Gelissen, I., White, A., Cohen, J. C., & Hobbs, H. H. (2002) · Journal of Clinical Investigation · doi:10.1172/jci16000 · Cited by 305
Schwartz, C. C., Halloran, L. G., Vlahcevic, Z. R., Gregory, D. H., & Swell, L. (1978) · Science · doi:10.1126/science.204996 · Cited by 302
Bortnick, A. E., Rothblat, G. H., Stoudt, G., Hoppe, K. L., Royer, L. J., McNeish, J., & Francone, O. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003407200 · Cited by 300
Wellington, C. L., Walker, E. K. Y., Suarez, A., Kwok, A., Bissada, N., Singaraja, R., Yang, Y.-Z., Zhang, L.-H., James, E., Wilson, J. E., et al. (2002) · Laboratory Investigation · doi:10.1038/labinvest.3780421 · Cited by 297
Claudel, T., Leibowitz, M. D., Fiévet, C., Tailleux, A., Wagner, B., Repa, J. J., Torpier, G., Lobaccaro, J.-M., Paterniti, J. R., Mangelsdorf, D. J., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.041609298 · Cited by 292
Bellosta, S., Mahley, R. W., Sanan, D. A., Murata, J., Newland, D. L., Taylor, J. M., & Pitas, R. E. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118271 · Cited by 284
Graf, G. A., Li, W.-P., Gerard, R. D., Gelissen, I., White, A., Cohen, J. C., & Hobbs, H. H. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0216000 · Cited by 283
Cellular Lipid Metabolism and the Role of Lipids in Progressive Renal Disease
Abrass, C. K. (2004) · American Journal of Nephrology · doi:10.1159/000075925 · Cited by 279
Oxidation of High Density Lipoproteins
Garner, B., Witting, P. K., Waldeck, A. R., Christison, J. K., Raftery, M., & Stocker, R. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.11.6080 · Cited by 278
Lipoprotein Physiology in Nondiabetic and Diabetic States: Relationship to Atherogenesis
Ginsberg, H. N. (1991) · Diabetes Care · doi:10.2337/diacare.14.9.839 · Cited by 277
Wang, N., Chen, W., Linsel-Nitschke, P., Martinez, L. O., Agerholm-Larsen, B., Silver, D. L., & Tall, A. R. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16808 · Cited by 277
Mechanisms of oxidative damage of low density lipoprotein in human atherosclerosis
Heinecke, J. W. (1997) · Current Opinion in Lipidology · doi:10.1097/00041433-199710000-00005 · Cited by 273
Self-citationJoyce, C. W., Amar, M. J. A., Lambert, G., Vaisman, B. L., Paigen, B., Najib-Fruchart, J., Hoyt, R. F., Neufeld, E. D., Remaley, A. T., Fredrickson, D. S., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012587699 · Cited by 269
Recent insights into stearoyl-CoA desaturase-1
Ntambi, J. M., & Miyazaki, M. (2003) · Current Opinion in Lipidology · doi:10.1097/00041433-200306000-00005 · Cited by 266
Role of ABCG1 and other ABCG family members in lipid metabolism
Schmitz, G., Langmann, T., & Heimerl, S. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32205-7 · Cited by 265
Tangier Disease: Combined Clinical Staff Conference at the National Institutes of Health
FREDRICKSON, D. S., ALTROCCHI, P. H., AVIOLI, L. V., GOODMAN, D. W. S., & GOODMAN, H. C. (1961) · Annals of Internal Medicine · doi:10.7326/0003-4819-55-6-1016 · Cited by 264
Pennathur, S., Bergt, C., Shao, B., Byun, J., Kassim, S. Y., Singh, P., Green, P. S., McDonald, T. O., Brunzell, J., Chait, A., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406762200 · Cited by 264
Self-citationHomozygous Tangier disease and cardiovascular disease
Serfaty-Lacrosniere, C., Civeira, F., Lanzberg, A., Isaia, P., Berg, J., Janus, E. D., Smith, M. P., Pritchard, P. H., Frohlich, J., Lees, R. S., et al. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90144-9 · Cited by 262
Human neutrophils employ chlorine gas as an oxidant during phagocytosis.
Hazen, S. L., Hsu, F. F., Mueller, D. M., Crowley, J. R., & Heinecke, J. W. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118914 · Cited by 258
Self-citationWang, N., & Tall, A. R. (2003) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000075912.83860.26 · Cited by 258
Jiang, X.-C., Qin, S., Qiao, C., Kawano, K., Lin, M., Skold, A., Xiao, X., & Tall, A. R. (2001) · Nature Medicine · doi:10.1038/89977 · Cited by 256
Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levels
Haghpassand, M., Bourassa, P.-A. K., Francone, O. L., & Aiello, R. J. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12810 · Cited by 256
Mendez, A. J., Oram, J. F., & Bierman, E. L. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99196-9 · Cited by 256
Self-citationHDL Apolipoproteins and ABCA1: Partners in the Removal of Excess Cellular Cholesterol
Oram, J. F. (2003) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000054662.44688.9a · Cited by 253
Self-citationIncreased ABCA1 activity protects against atherosclerosis
Singaraja, R. R., Fievet, C., Castro, G., James, E. R., Hennuyer, N., Clee, S. M., Bissada, N., Choy, J. C., Fruchart, J.-C., McManus, B. M., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15748 · Cited by 250
Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population
Frikke-Schmidt, R., Nordestgaard, B. G., Jensen, G. B., & Tybjærg-Hansen, A. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420361 · Cited by 250
Efflux and Atherosclerosis: The Clinical and Biochemical Impact of Variations in the ABCA1 Gene
Singaraja, R. R., Brunham, L. R., Visscher, H., Kastelein, J. J. P., & Hayden, M. R. (2003) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000078520.89539.77 · Cited by 245
Nagano, Y., Arai, H., & Kita, T. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.15.6457 · Cited by 245
Koldamova, R. P., Lefterov, I. M., Ikonomovic, M. D., Skoko, J., Lefterov, P. I., Isanski, B. A., DeKosky, S. T., & Lazo, J. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300044200 · Cited by 237
Development of the Lipid-Rich Core in Human Atherosclerosis
Guyton, J. R., & Klemp, K. F. (1996) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.16.1.4 · Cited by 236
Takahashi, Y., & Smith, J. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11358 · Cited by 236
Christiansen-Weber, T. A., Voland, J. R., Wu, Y., Ngo, K., Roland, B. L., Nguyen, S., Peterson, P. A., & Fung-Leung, W.-P. (2000) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64614-7 · Cited by 235
Shao, B., Bergt, C., Fu, X., Green, P., Voss, J. C., Oda, M. N., Oram, J. F., & Heinecke, J. W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411484200 · Cited by 228
Self-citationLeukocytic Oxygen Activation and Microbicidal Oxidative Toxin
Hurst, J. K., & Barrette, W. C. (1989) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238909082555 · Cited by 228
Wang, Y., & Oram, J. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109977200 · Cited by 225
Self-citationInterleukin-1β Secretion Is Impaired by Inhibitors of the Atp Binding Cassette Transporter, ABC1
Hamon, Y., Luciani, M.-F., Becq, F., Verrier, B., Rubartelli, A., & Chimini, G. (1997) · Blood · doi:10.1182/blood.v90.8.2911 · Cited by 224
Specific Docking of Apolipoprotein A-I at the Cell Surface Requires a Functional ABCA1 Transporter
Chambenoit, O., Hamon, Y., Marguet, D., Rigneault, H., Rosseneu, M., & Chimini, G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010265200 · Cited by 209
LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells
Murthy, S., Born, E., Mathur, S. N., & Field, F. J. (2002) · Journal of Lipid Research · doi:10.1194/jlr.m100358-jlr200 · Cited by 208
Zheng, L., Settle, M., Brubaker, G., Schmitt, D., Hazen, S. L., Smith, J. D., & Kinter, M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m407019200 · Cited by 207
Fitzgerald, M. L., Morris, A. L., Rhee, J. S., Andersson, L. P., Mendez, A. J., & Freeman, M. W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204996200 · Cited by 205
Myeloperoxidase produces nitrating oxidants in vivo
Gaut, J. P., Byun, J., Tran, H. D., Lauber, W. M., Carroll, J. A., Hotchkiss, R. S., Belaaouaj, A., & Heinecke, J. W. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15021 · Cited by 202
Self-citationFielding, P. E., Nagao, K., Hakamata, H., Chimini, G., & Fielding, C. J. (2000) · Biochemistry · doi:10.1021/bi0004192 · Cited by 202
ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions
Vaughan, A. M., & Oram, J. F. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m300078-jlr200 · Cited by 202
Self-citationWang, N., Lan, D., Gerbod-Giannone, M., Linsel-Nitschke, P., Jehle, A. W., Chen, W., Martinez, L. O., & Tall, A. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307831200 · Cited by 201
Arakawa, R., & Yokoyama, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202996200 · Cited by 200
High density lipoprotein conversion mediated by human plasma phospholipid transfer protein.
Tu, A. Y., Nishida, H. I., & Nishida, T. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)49431-3 · Cited by 199
Cheung, M., Brown, B., Wolf, A., & Albers, J. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42061-9 · Cited by 199
van Dam, M. J., de Groot, E., Clee, S. M., Hovingh, G. K., Roelants, R., Brooks-Wilson, A., Zwinderman, A. H., Smit, A. J., Smelt, A. H., Groen, A. K., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07277-x · Cited by 198
Remaley, A. T., Thomas, F., Stonik, J. A., Demosky, S. J., Bark, S. E., Neufeld, E. B., Bocharov, A. V., Vishnyakova, T. G., Patterson, A. P., Eggerman, T. L., et al. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m200475-jlr200 · Cited by 195
Rosenberg, M. F., Kamis, A. B., Callaghan, R., Higgins, C. F., & Ford, R. C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211758200 · Cited by 194
Chiesa, G., Monteggia, E., Marchesi, M., Lorenzon, P., Laucello, M., Lorusso, V., Di Mario, C., Karvouni, E., Newton, R. S., Bisgaier, C. L., et al. (2002) · Circulation Research · doi:10.1161/01.res.0000018422.31717.ee · Cited by 194
The ABCA1 Transporter Modulates Late Endocytic Trafficking
Neufeld, E. B., Stonik, J. A., Demosky, S. J., Knapper, C. L., Combs, C. A., Cooney, A., Comly, M., Dwyer, N., Blanchette-Mackie, J., Remaley, A. T., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m314160200 · Cited by 193
Mendez, A. J., Lin, G., Wade, D. P., Lawn, R. M., & Oram, J. F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m007717200 · Cited by 191
Self-citationMiyazaki, A., Sakuma, S., Morikawa, W., Takiue, T., Miake, F., Terano, T., Sakai, M., Hakamata, H., Sakamoto, Y.-I., Naito, M., et al. (1995) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.15.11.1882 · Cited by 191
Hoffman, J. S., & Benditt, E. P. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34047-x · Cited by 190
Yancey, P. G., Bielicki, J. K., Johnson, W. J., Lund-Katz, S., Palgunachari, M. N., Anantharamaiah, G. M., Segrest, J. P., Phillips, M. C., & Rothblat, G. H. (1995) · Biochemistry · doi:10.1021/bi00024a021 · Cited by 189
Mendez, A. J., Anantharamaiah, G. M., Segrest, J. P., & Oram, J. F. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117515 · Cited by 189
Self-citationAbe-Dohmae, S., Ikeda, Y., Matsuo, M., Hayashi, M., Okuhira, K.-I., Ueda, K., & Yokoyama, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309888200 · Cited by 188
ATP-binding cassette transporter AI and its role in HDL formation
Lee, J.-Y., & Parks, J. S. (2005) · Current Opinion in Lipidology · doi:10.1097/00041433-200502000-00005 · Cited by 187
Miao, B., Zondlo, S., Gibbs, S., Cromley, D., Hosagrahara, V. P., Kirchgessner, T. G., Billheimer, J., & Mukherjee, R. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300450-jlr200 · Cited by 186
Phosphorylation of a Pest Sequence in ABCA1 Promotes Calpain Degradation and Is Reversed by ApoA-I
Martinez, L. O., Agerholm-Larsen, B., Wang, N., Chen, W., & Tall, A. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307161200 · Cited by 185
Apolipoprotein-mediated Plasma Membrane Microsolubilization
Gillotte, K. L., Zaiou, M., Lund-Katz, S., Anantharamaiah, G. M., Holvoet, P., Dhoest, A., Palgunachari, M. N., Segrest, J. P., Weisgraber, K. H., Rothblat, G. H., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.4.2021 · Cited by 184
Huang, Y., von Eckardstein, A., Wu, S., Maeda, N., & Assmann, G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.5.1834 · Cited by 181
Nuclear receptor regulation of cholesterol and bile acid metabolism
Repa, J. J., & Mangelsdorf, D. J. (1999) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(99)00031-2 · Cited by 180
Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion
Sun, Y., Yao, J., Kim, T.-W., & Tall, A. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300760200 · Cited by 179
ABCA1 Gene Deletion Protects against Cerebral Malaria
Combes, V., Coltel, N., Alibert, M., van Eck, M., Raymond, C., Juhan-Vague, I., Grau, G. E., & Chimini, G. (2005) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)62253-5 · Cited by 178
Jiang, X., Francone, O. L., Bruce, C., Milne, R., Mar, J., Walsh, A., Breslow, J. L., & Tall, A. R. (1996) · Journal of Clinical Investigation · doi:10.1172/jci119050 · Cited by 177
Bungert, S., Molday, L. L., & Molday, R. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101902200 · Cited by 173
Huszar, D., Varban, M. L., Rinninger, F., Feeley, R., Arai, T., Fairchild-Huntress, V., Donovan, M. J., & Tall, A. R. (2000) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.20.4.1068 · Cited by 173
Panzenboeck, U., Balazs, Z., Sovic, A., Hrzenjak, A., Levak-Frank, S., Wintersperger, A., Malle, E., & Sattler, W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207601200 · Cited by 169
ATP-binding Cassette Transporter A1 Mediates Cellular Secretion of α-Tocopherol
Oram, J. F., Vaughan, A. M., & Stocker, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106984200 · Cited by 169
Self-citationKruth, H. S., Comly, M. E., Butler, J. D., Vanier, M. T., Fink, J. K., Wenger, D. A., Patel, S., & Pentchev, P. G. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66632-3 · Cited by 165
The Role of High-Density Lipoproteins in Oxidation and Inflammation
Van Lenten, B. (2001) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(01)00095-0 · Cited by 165
Identification of a Novel Human Sterol-Sensitive ATP-Binding Cassette Transporter (ABCA7)
Kaminski, W. E., Orsó, E., Diederich, W., Klucken, J., Drobnik, W., & Schmitz, G. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2954 · Cited by 164
Nakamura, K., Kennedy, M. A., Baldán, Á., Bojanic, D. D., Lyons, K., & Edwards, P. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408652200 · Cited by 163
Laffitte, B. A., Joseph, S. B., Chen, M., Castrillo, A., Repa, J., Wilpitz, D., Mangelsdorf, D., & Tontonoz, P. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.6.2182-2191.2003 · Cited by 163
Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL
Groen, A. K., Bloks, V. W., Bandsma, R. H. J., Ottenhoff, R., Chimini, G., & Kuipers, F. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12473 · Cited by 162
The Structure of the Multidrug Resistance Protein 1 (MRP1/ABCC1)
Rosenberg, M. F., Mao, Q., Holzenburg, A., Ford, R. C., Deeley, R. G., & Cole, S. P. C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100176200 · Cited by 161
ATP-binding cassette transporter A1 and cholesterol trafficking
Oram, J. F. (2002) · Current Opinion in Lipidology · doi:10.1097/00041433-200208000-00004 · Cited by 161
Self-citationFukumoto, H., Deng, A., Irizarry, M. C., Fitzgerald, M. L., & Rebeck, G. W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209085200 · Cited by 160
Drobnik, W., Borsukova, H., Böttcher, A., Pfeiffer, A., Liebisch, G., Schütz, G. J., Schindler, H., & Schmitz, G. (2002) · Traffic · doi:10.1034/j.1600-0854.2002.030404.x · Cited by 158
Regulation and intracellular trafficking of the ABCA1 transporter
Santamarina-Fojo, S., Remaley, A. T., Neufeld, E. B., & Brewer, H. B. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30266-2 · Cited by 158
Toward the rational design of protein kinase casein kinase-2 inhibitors
Sarno, S., Moro, S., Meggio, F., Zagotto, G., Ben, D. D., Ghisellini, P., Battistutta, R., Zanotti, G., & Pinna, L. A. (2002) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00185-7 · Cited by 156
Crawford, A. R., Smith, A. J., Hatch, V., Elferink, R. P. J. O., Borst, P., & Crawford, J. M. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119799 · Cited by 155
Liver X Receptor (LXR) Regulation of the LXRα Gene in Human Macrophages
Whitney, K. D., Watson, M. A., Goodwin, B., Galardi, C. M., Maglich, J. M., Wilson, J. G., Willson, T. M., Collins, J. L., & Kliewer, S. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106155200 · Cited by 154
Oram, J. F., Wolfbauer, G., Vaughan, A. M., Tang, C., & Albers, J. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m310695200 · Cited by 152
Self-citationFeng, B., Zhang, D., Kuriakose, G., Devlin, C. M., Kockx, M. M., & Tabas, I. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1732494100 · Cited by 148
ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease
Wollmer, M. A., Streffer, J. R., Lütjohann, D., Tsolaki, M., Iakovidou, V., Hegi, T., Pasch, T., Jung, H. H., von Bergmann, K., Nitsch, R. M., et al. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00094-5 · Cited by 147
Aiello, R. J., Brees, D., & Francone, O. L. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000054661.21499.fb · Cited by 145
Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor
Quinet, E. M., Savio, D. A., Halpern, A. R., Chen, L., Miller, C. P., & Nambi, P. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400257-jlr200 · Cited by 144
ABCA1-mediated Cholesterol Efflux Is Defective in Free Cholesterol-loaded Macrophages
Feng, B., & Tabas, I. A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207532200 · Cited by 143
Tanaka, A. R., Abe-Dohmae, S., Ohnishi, T., Aoki, R., Morinaga, G., Okuhira, K., Ikeda, Y., Kano, F., Matsuo, M., Kioka, N., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m206885200 · Cited by 141
Choi, H. Y., Karten, B., Chan, T., Vance, J. E., Greer, W. L., Heidenreich, R. A., Garver, W. S., & Francis, G. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304553200 · Cited by 138
Hannuksela, M. L., Liinamaa, J., Kesäniemi, Y. A., & Savolainen, M. J. (1994) · Atherosclerosis · doi:10.1016/0021-9150(94)90065-5 · Cited by 138
Retinoic Acid Receptor-Mediated Induction of ABCA1 in Macrophages
Costet, P., Lalanne, F., Gerbod-Giannone, M. C., Molina, J. R., Fu, X., Lund, E. G., Gudas, L. J., & Tall, A. R. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.21.7756-7766.2003 · Cited by 138
Advanced Glycation End Product Precursors Impair ABCA1-Dependent Cholesterol Removal From Cells
Passarelli, M., Tang, C., McDonald, T. O., O’Brien, K. D., Gerrity, R. G., Heinecke, J. W., & Oram, J. F. (2005) · Diabetes · doi:10.2337/diabetes.54.7.2198 · Cited by 138
Self-citationFitzgerald, M. L., Morris, A. L., Chroni, A., Mendez, A. J., Zannis, V. I., & Freeman, M. W. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300355-jlr200 · Cited by 137
Kim, W. S., Fitzgerald, M. L., Kang, K., Okuhira, K., Bell, S. A., Manning, J. J., Koehn, S. L., Lu, N., Moore, K. J., & Freeman, M. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m412602200 · Cited by 135
Jansen, H., Verhoeven, A. J. M., & Sijbrands, E. J. G. (2002) · Journal of Lipid Research · doi:10.1194/jlr.r200008-jlr200 · Cited by 135
Yamauchi, Y., Hayashi, M., Abe-Dohmae, S., & Yokoyama, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306258200 · Cited by 134
Cited by
Mechanisms and regulation of cholesterol homeostasis
Luo, J., Yang, H., & Song, B.-L. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0190-7 · Cited by 1,980
Apoptotic cell clearance: basic biology and therapeutic potential
Poon, I. K. H., Lucas, C. D., Rossi, A. G., & Ravichandran, K. S. (2014) · Nature Reviews Immunology · doi:10.1038/nri3607 · Cited by 1,223
Phagocytosis of apoptotic cells in homeostasis
Arandjelovic, S., & Ravichandran, K. S. (2015) · Nature Immunology · doi:10.1038/ni.3253 · Cited by 959
Allahverdian, S., Chehroudi, A. C., McManus, B. M., Abraham, T., & Francis, G. A. (2014) · Circulation · doi:10.1161/circulationaha.113.005015 · Cited by 748
Cholesterol metabolism and homeostasis in the brain
Zhang, J., & Liu, Q. (2015) · Protein & Cell · doi:10.1007/s13238-014-0131-3 · Cited by 686
Metadata
- Authors
- Oram, J. F., & Heinecke, J. W.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 2005-10
- Volume
- 85
- Issue
- 4
- Pages
- 1343-1372
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2059256286
- Cited by
- 521
- References
- 316
- FWCI
- 5.50
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.