Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero, Jesús, Shiva, Sruti, Gladwin, Mark T.·2019·Physiological Reviews

Cites (1,088)

Items 401–600 of 1,091

  1. Folic Acid Reverts Dysfunction of Endothelial Nitric Oxide Synthase
    Stroes, E. S. G., van Faassen, E. E., Yo, M., Martasek, P., Boer, P., Govers, R., Rabelink, T. J. · 2000 · Circulation Research
  2. Nitrite Reductase Function of Deoxymyoglobin: Oxygen Sensor and Regulator of Cardiac Energetics and Function
    Rassaf, Tienush, Flögel, Ulrich, Drexhage, Christine, Hendgen-Cotta, Ulrike, Kelm, Malte, Schrader, Jürgen · 2007 · Circulation Research
  3. Roles of Cyclooxygenase (COX)-1 and COX-2 in Prostanoid Production by Human Endothelial Cells: Selective Up-Regulation of Prostacyclin Synthesis by COX-2
    Caughey, Gillian E, Cleland, Leslie G, Penglis, Peter S, Gamble, Jennifer R, James, Michael J · 2001 · The Journal of Immunology
  4. Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCɛ signaling axis in pulmonary artery smooth muscle cells
    Rathore, Rakesh, Zheng, Yun-Min, Niu, Chun-Feng, Liu, Qing-Hua, Korde, Amit, Ho, Ye-Shih, Wang, Yong-Xiao · 2008 · Free Radical Biology and Medicine
  5. NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation
    Craige, Siobhan M., Chen, Kai, Pei, Yongmei, Li, Chunying, Huang, Xiaoyun, Chen;, Christine, Shibata, Rei, Sato, Kaori, Walsh, Kenneth, Keaney, John F. · 2011 · Circulation
  6. Carbon monoxide, reactive oxygen signaling, and oxidative stress
    Piantadosi, Claude A. · 2008 · Free Radical Biology and Medicine
  7. Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease
    Guzik, Tomasz J., Chen, Wei, Gongora, Maria C., Guzik, Bartlomiej, Lob, Heinrich E., Mangalat, Deepa, Hoch, Nyssa, Dikalov, Sergey, Rudzinski, Pawel, Kapelak, Boguslaw et al. · 2008 · Journal of the American College of Cardiology
  8. Proteins Homologous to p47 and p67 Support Superoxide Production by NAD(P)H Oxidase 1 in Colon Epithelial Cells
    Geiszt, Miklós, Lekstrom, Kristen, Witta, Jassir, Leto, Thomas L. · 2003 · Journal of Biological Chemistry
  9. Characterization of the Magnitude and Kinetics of Xanthine Oxidase-catalyzed Nitrite Reduction
    Li, Haitao, Samouilov, Alexandre, Liu, Xiaoping, Zweier, Jay L. · 2001 · Journal of Biological Chemistry
  10. Coronary Artery Superoxide Production and Nox Isoform Expression in Human Coronary Artery Disease
    Guzik, Tomasz J., Sadowski, Jerzy, Guzik, Bartlomiej, Jopek, Andrew, Kapelak, Boguslaw, Przybyłowski, Piotr, Wierzbicki, Karol, Korbut, Ryszard, Harrison, David G., Channon, Keith M. · 2006 · Arteriosclerosis, Thrombosis, and Vascular Biology
  11. Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase
    Elsa D. Garcin, Andrew S. Arvai, Robin J. Rosenfeld, M.D. Kroeger, Brian R. Crane, Gunilla Andersson, Glen Andrews, Peter J. Hamley, Philip R. Mallinder, David Nicholls et al. · 2008 · Nature Chemical Biology
  12. Proteolytic conversion of xanthine dehydrogenase from the NAD-dependent type to the O2-dependent type. Amino acid sequence of rat liver xanthine dehydrogenase and identification of the cleavage sites of the enzyme protein during irreversible conversion by trypsin.
    Amaya, Y., Yamazaki, K., Sato, M., Noda, K., Nishino, T., Nishino, T. · 1990 · Journal of Biological Chemistry
  13. The superoxide‐producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells
    Kuroda, Junya, Nakagawa, Kazunori, Yamasaki, Tomoko, Nakamura, Kei‐ichiro, Takeya, Ryu, Kuribayashi, Futoshi, Imajoh‐Ohmi, Shinobu, Igarashi, Kazuhiko, Shibata, Yosaburo, Sueishi, Katsuo et al. · 2005 · Genes to Cells
  14. Nitric oxide dioxygenase function and mechanism of flavohemoglobin, hemoglobin, myoglobin and their associated reductases
    Paul R. Gardner · 2004 · Journal of Inorganic Biochemistry
  15. Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes
    Josephson, R A, Silverman, H S, Lakatta, E G, Stern, M D, Zweier, J L · 1991 · Journal of Biological Chemistry
  16. NADPH oxidase of human neutrophils. Subcellular localization and characterization of an arachidonate-activatable superoxide-generating system.
    Clark, R.A., Leidal, K.G., Pearson, D.W., Nauseef, W.M. · 1987 · Journal of Biological Chemistry
  17. Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling
    Brian C. Smith, Michael A. Marletta · 2012 · Current Opinion in Chemical Biology
  18. Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury
    Hazel H. Szeto · 2007 · Antioxidants and Redox Signaling
  19. Nitric Oxide Production from Nitrite Occurs Primarily in Tissues Not in the Blood
    Li, Haitao, Cui, Hongmei, Kundu, Tapan Kumar, Alzawahra, Wael, Zweier, Jay L. · 2008 · Journal of Biological Chemistry
  20. Clinical Efficacy and Safety of Successful Longterm Urate Lowering with Febuxostat or Allopurinol in Subjects with Gout
    BECKER, MICHAEL A., SCHUMACHER, H. RALPH, MacDONALD, PATRICIA A., LLOYD, ERIC, LADEMACHER, CHRISTOPHER · 2009 · The Journal of Rheumatology
  21. Remnant Lipoprotein Particles Induce Apoptosis in Endothelial Cells by NAD(P)H Oxidase–Mediated Production of Superoxide and Cytokines via Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Activation: Prevention by Cilostazol
    Shin, Hwa Kyoung, Kim, Yong Ki, Kim, Ki Young, Lee, Jeong Hyun, Hong, Ki Whan · 2004 · Circulation
  22. Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice
    Ozaki, Masanori, Kawashima, Seinosuke, Yamashita, Tomoya, Hirase, Tetsuaki, Namiki, Masayuki, Inoue, Nobutaka, Hirata, Ken-ichi, Yasui, Hiroyuki, Sakurai, Hiromu, Yoshida, Yuichi et al. · 2002 · Journal of Clinical Investigation
  23. Role of NAD(P)H Oxidase- and Mitochondria-Derived Reactive Oxygen Species in Cardioprotection of Ischemic Reperfusion Injury by Angiotensin II
    Kimura, Shoji, Zhang, Guo-Xing, Nishiyama, Akira, Shokoji, Takatomi, Yao, Li, Fan, Yu-Yan, Rahman, Matlubur, Suzuki, Takeo, Maeta, Hajime, Abe, Youichi · 2005 · Hypertension
  24. S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity
    Kandasam Ravi, Lisa Brennan, Snezana Levic, Patrick A. Ross, Stephen M. Black · 2004 · Proceedings of the National Academy of Sciences
  25. Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP.
    Werner-Felmayer, G., Werner, E.R., Fuchs, D., Hausen, A., Reibnegger, G., Schmidt, K., Weiss, G., Wachter, H. · 1993 · Journal of Biological Chemistry
  26. The chemical biology of S-nitrosothiols
    Broniowska, Katarzyna A., Hogg, Neil · 2012 · Antioxidants & Redox Signaling
  27. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation☆
    TENFREYHAUS, H, HUNTGEBURTH, M, WINGLER, K, SCHNITKER, J, BAUMER, A, VANTLER, M, BEKHITE, M, WARTENBERG, M, SAUER, H, ROSENKRANZ, S · 2006 · Cardiovascular Research
  28. Pathophysiology of circulating xanthine oxidoreductase: New emerging roles for a multi-tasking enzyme
    Battelli, Maria Giulia, Bolognesi, Andrea, Polito, Letizia · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  29. Interaction of Neuronal Nitric-oxide Synthase with Caveolin-3 in Skeletal Muscle
    Venema, Virginia J., Ju, Hong, Zou, Rong, Venema, Richard C. · 1997 · Journal of Biological Chemistry
  30. gp91phox-Containing NADPH Oxidase Mediates Endothelial Dysfunction in Renovascular Hypertension
    O. Jung, Judith G. Schreiber, Helmut Geiger, Thierry Pedrazzini, Rudi Busse, Ralf Peter Brandes · 2004 · Circulation
  31. NOX5 variants are functionally active in endothelial cells
    BelAiba, Rachida S., Djordjevic, Talija, Petry, Andreas, Diemer, Kerstin, Bonello, Steve, Banfi, Botond, Hess, John, Pogrebniak, Alexej, Bickel, Christian, Görlach, Agnes · 2007 · Free Radical Biology and Medicine
  32. Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells
    Basuroy, Shyamali, Bhattacharya, Sujoy, Leffler, Charles W., Parfenova, Helena · 2009 · American Journal of Physiology-Cell Physiology
  33. Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress
    Eberhard Schulz, Philip Wenzel, Thomas F. Münzel, Andreas Daiber · 2012 · Antioxidants and Redox Signaling
  34. The Reaction between Nitrite and Deoxyhemoglobin
    Huang, Kris T., Keszler, Agnes, Patel, Neil, Patel, Rakesh P., Gladwin, Mark T., Kim-Shapiro, Daniel B., Hogg, Neil · 2005 · Journal of Biological Chemistry
  35. The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system
    Kietzmann, Thomas, Petry, Andreas, Shvetsova, Antonina, Gerhold, Joachim M, Görlach, Agnes · 2017 · British Journal of Pharmacology
  36. Genetic Deficiency of Inducible Nitric Oxide Synthase Reduces Atherosclerosis and Lowers Plasma Lipid Peroxides in Apolipoprotein E–Knockout Mice
    Peter Jan Kuhlencordt, Jiqiu Chen, Fred Han, Joshua Astern, Paul Lee Huang · 2001 · Circulation
  37. NO synthase: Structures and mechanisms
    Daff, Simon · 2010 · Nitric Oxide
  38. Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines
    Zhao, Kesheng, Luo, Guoxiong, Giannelli, Serena, Szeto, Hazel H. · 2005 · Biochemical Pharmacology
  39. Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo
    Jiang, Joy X., Chen, Xiangling, Serizawa, Nobuko, Szyndralewiez, Cédric, Page, Patrick, Schröder, Katrin, Brandes, Ralf P., Devaraj, Sridevi, Török, Natalie J. · 2012 · Free Radical Biology and Medicine
  40. Production of Reactive Oxygen Species by Microsomes Enriched in Specific Human Cytochrome P450 Enzymes
    Susana Puntarulo, Arthur I. Cederbaum · 1998 · Free Radical Biology and Medicine
  41. Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
    Imad Al Ghouleh, Nicholas K.H. Khoo, Ulla G. Knaus, Kathy K. Griendling, Rhian M. Touyz, Victor John Thannickal, Aaron Barchowsky, William Michael Nauseef, Eric E. Kelley, Phillip Michael Bauer et al. · 2011 · Free Radical Biology and Medicine
  42. Dual Oxidase-2 Has an Intrinsic Ca2+-dependent H2O2-generating Activity
    Ameziane-El-Hassani, Rabii, Morand, Stanislas, Boucher, Jean-Luc, Frapart, Yves-Michel, Apostolou, Daphné, Agnandji, Diane, Gnidehou, Sédami, Ohayon, Renée, Noël-Hudson, Marie-Sophie, Francon, Jacques et al. · 2005 · Journal of Biological Chemistry
  43. Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid
    Winterbourn, Christine C. · 2002 · Toxicology
  44. Mitochondrial Respiratory Chain and NAD(P)H Oxidase Are Targets for theAntiproliferative Effect of Carbon Monoxide in Human Airway SmoothMuscle
    Taillé, Camille, El-Benna, Jamel, Lanone, Sophie, Boczkowski, Jorge, Motterlini, Roberto · 2005 · Journal of Biological Chemistry
  45. Evidence for the Pathophysiological Role of Endogenous Methylarginines in Regulation of Endothelial NO Production and Vascular Function
    Arturo Juan Cardounel, Hongmei Cui, Alexandre Samouilov, Wesley Johnson, Patrick N. Kearns, Ah-Lim Tsai, V. Berka, Jay Louis Zweier · 2006 · Journal of Biological Chemistry
  46. Sickle cell disease vasculopathy: A state of nitric oxide resistance
    Katherine C. Wood, Lewis Li-yen Hsu, Mark T. Gladwin · 2008 · Free Radical Biology and Medicine
  47. Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
    Björne, Håkan, Petersson, Joel, Phillipson, Mia, Weitzberg, Eddie, Holm, Lena, Lundberg, Jon O. · 2004 · Journal of Clinical Investigation
  48. Immunohistochemical evidence for the myeloperoxidase/H<sub>2</sub>O<sub>2</sub>/halide system in human atherosclerotic lesions: Colocalization of myeloperoxidase and hypochlorite‐modified proteins
    Malle, Ernst, Waeg, Georg, Schreiber, Renate, Gröne, Elisabeth F., Sattler, Wolfgang, Gröne, Hermann‐Josef · 2000 · European Journal of Biochemistry
  49. Compensatory Phosphorylation and Protein-Protein Interactions Revealed by Loss of Function and Gain of Function Mutants of Multiple Serine Phosphorylation Sites in Endothelial Nitric-oxide Synthase
    Philip Michael Bauer, David J. Fulton, Yong Chool Boo, George P. Sorescu, Bruce E. Kemp, Hanjoong Jo, William C. Sessa · 2003 · Journal of Biological Chemistry
  50. Regulation of NAD(P)H Oxidase by Associated Protein Disulfide Isomerase in Vascular Smooth Muscle Cells
    Mariano Janiszewski, Lucia Rossetti Lopes, Alipio O. Carmo, Marcelo de Almeida Pedro, Ralf Peter Brandes, Célio X.C. Santos, Francisco Rafael Martins Laurindo · 2005 · Journal of Biological Chemistry
  51. NOX2 and NOX4 Mediate Proliferative Response in Endothelial Cells
    Petry, Andreas, Djordjevic, Talija, Weitnauer, Michael, Kietzmann, Thomas, Hess, John, Görlach, Agnes · 2006 · Antioxidants &amp; Redox Signaling
  52. First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
    Laleu, Benoı̂t, Gaggini, Francesca, Orchard, Mike, Fioraso-Cartier, Laetitia, Cagnon, Laurène, Houngninou-Molango, Sophie, Gradia, Angelo, Duboux, Guillaume, Merlot, Cédric, Heitz, Freddy et al. · 2010 · Journal of Medicinal Chemistry
  53. How do dietary flavanols improve vascular function? A position paper
    Tankred SCHEWE, Yvonne Steffen, Helmut Sies · 2008 · Archives of Biochemistry and Biophysics
  54. Tks5-Dependent, Nox-Mediated Generation of Reactive Oxygen Species Is Necessary for Invadopodia Formation
    Diaz, Begoña, Shani, Gidon, Pass, Ian, Anderson, Diana, Quintavalle, Manuela, Courtneidge, Sara A. · 2009 · Science Signaling
  55. Comparative pharmacology of chemically distinct nadph oxidase inhibitors
    Wind, S, Beuerlein, K, Eucker, T, Müller, H, Scheurer, P, Armitage, ME, Ho, H, Schmidt, HHHW, Wingler, K · 2010 · British Journal of Pharmacology
  56. <scp>l</scp> -Arginine Supplementation in Peripheral Arterial Disease: No Benefit and Possible Harm
    Wilson, Andrew M., Harada, Randall, Nair, Nandini, Balasubramanian, Naras, Cooke, John P. · 2007 · Circulation
  57. Antimicrobial effect of acidified nitrite on gut pathogens: importance of dietary nitrate in host defense
    Dykhuizen, R S, Frazer, R, Duncan, C, Smith, C C, Golden, M, Benjamin, N, Leifert, C · 1996 · Antimicrobial Agents and Chemotherapy
  58. Intramitochondrial signaling: interactions among mitoK<sub>ATP</sub>, PKCε, ROS, and MPT
    Costa, Alexandre D. T., Garlid, Keith D. · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
  59. Endogenous nitric oxide synthase inhibitors are responsible for the <scp>L</scp>‐arginine paradox
    Tsikas, Dimitrios, Böger, Rainer H, Sandmann, Jörg, Bode-Böger, Stefanie M, Frölich, Jürgen C · 2000 · FEBS Letters
  60. Xanthine oxidoreductase-catalyzed reactive species generation: A process in critical need of reevaluation
    Cantu-Medellin, Nadiezhda, Kelley, Eric E. · 2013 · Redox Biology
  61. Phosphorylation of Threonine 497 in Endothelial Nitric-oxide Synthase Coordinates the Coupling of l-Arginine Metabolism to Efficient Nitric Oxide Production
    Michelle I. Lin, David J. Fulton, Roger W. Babbitt, Ingrid Fleming, Rudi Busse, Kirkwood A. Pritchard, William C. Sessa · 2003 · Journal of Biological Chemistry
  62. Cystathionine β-Synthase: Structure, Function, Regulation, and Location of Homocystinuria-causing Mutations
    Edith Wilson Miles, Jan Peter Kraus · 2004 · Journal of Biological Chemistry
  63. Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis
    Ryoo, Sungwoo, Gupta, Gaurav, Benjo, Alexandre, Lim, Hyun Kyo, Camara, Andre, Sikka, Gautam, Lim, Hyun Kyung, Sohi, Jayson, Santhanam, Lakshmi, Soucy, Kevin et al. · 2008 · Circulation Research
  64. Requirement of argininosuccinate lyase for systemic nitric oxide production
    Erez, Ayelet, Nagamani, Sandesh C S, Shchelochkov, Oleg A, Premkumar, Muralidhar H, Campeau, Philippe M, Chen, Yuqing, Garg, Harsha K, Li, Li, Mian, Asad, Bertin, Terry K et al. · 2011 · Nature Medicine
  65. Distinction between signaling mechanisms in lipid rafts vs. caveolae
    Sowa, Grzegorz, Pypaert, Marc, Sessa, William C. · 2001 · Proceedings of the National Academy of Sciences
  66. Tetrahydrobiopterin in Cardiovascular Health and Disease
    Bendall, Jennifer K., Douglas, Gillian, McNeill, Eileen, Channon, Keith M., Crabtree, Mark J. · 2014 · Antioxidants &amp; Redox Signaling
  67. Oxidative Stress Causes Heart Failure with Impaired Mitochondrial Respiration
    Nojiri, Hidetoshi, Shimizu, Takahiko, Funakoshi, Masabumi, Yamaguchi, Osamu, Zhou, Heying, Kawakami, Satoru, Ohta, Yutaka, Sami, Manabu, Tachibana, Toshiaki, Ishikawa, Hiroshi et al. · 2006 · Journal of Biological Chemistry
  68. Function and evolution of vertebrate globins
    Thorsten Burmester, Thomas Hankeln · 2014 · Acta Physiologica
  69. Metformin attenuates lung fibrosis development via NOX4 suppression
    Nahoko Sato, Naoki Takasaka, Masahiro Yoshida, Kazuya Tsubouchi, Shunsuke Minagawa, Jun Araya, Nayuta Saito, Yu Fujita, Yusuke Kurita, Kenji Kobayashi et al. · 2016 · Respiratory Research
  70. Effect of oral l-arginine supplementation on blood pressure: A meta-analysis of randomized, double-blind, placebo-controlled trials
    Dong, Jia-Yi, Qin, Li-Qiang, Zhang, Zengli, Zhao, Youyou, Wang, Junkuan, Arigoni, Fabrizio, Zhang, Weiguo · 2011 · American Heart Journal
  71. Xanthine Oxidase Inhibition Reverses Endothelial Dysfunction in Heavy Smokers
    Guthikonda, Sashi, Sinkey, Christine, Barenz, Therese, Haynes, William G. · 2003 · Circulation
  72. Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin
    Basu, Swati, Grubina, Rozalina, Huang, Jinming, Conradie, Jeanet, Huang, Zhi, Jeffers, Anne, Jiang, Alice, He, Xiaojun, Azarov, Ivan, Seibert, Ryan et al. · 2007 · Nature Chemical Biology
  73. Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells
    Stavros Selemidis, G. J. Dusting, Hitesh Peshavariya, Barbara K. Kemp‐Harper, Grant Raymond Drummond · 2007 · Cardiovascular Research
  74. Emerging role of nitrite in human biology
    Dejam, André, Hunter, Christian J, Schechter, Alan N, Gladwin, Mark T · 2004 · Blood Cells, Molecules, and Diseases
  75. The Pharmacodynamics of L-Arginine
    Böger, Rainer H. · 2007 · The Journal of Nutrition
  76. Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation
    Sayed, Nazish, Baskaran, Padmamalini, Ma, Xiaolei, van den Akker, Focco, Beuve, Annie · 2007 · Proceedings of the National Academy of Sciences
  77. The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain.
    Klatt, P., Schmid, M., Leopold, E., Schmidt, K., Werner, E.R., Mayer, B. · 1994 · Journal of Biological Chemistry
  78. Rapid, Direct Effects of Statin Treatment on Arterial Redox State and Nitric Oxide Bioavailability in Human Atherosclerosis via Tetrahydrobiopterin-Mediated Endothelial Nitric Oxide Synthase Coupling
    Antoniades, Charalambos, Bakogiannis, Constantinos, Leeson, Paul, Guzik, Tomasz J., Zhang, Mei-Hua, Tousoulis, Dimitris, Antonopoulos, Alexios S., Demosthenous, Michael, Marinou, Kyriakoula, Hale, Ashley et al. · 2011 · Circulation
  79. Nitroxidative, Nitrosative, and Nitrative Stress:  Kinetic Predictions of Reactive Nitrogen Species Chemistry Under Biological Conditions
    Lancaster, Jack R. · 2006 · Chemical Research in Toxicology
  80. Enhanced Vasodilator Activity of Nitrite in Hypertension: Critical Role for Erythrocytic Xanthine Oxidoreductase and Translational Potential
    Ghosh, Suborno M., Kapil, Vikas, Fuentes-Calvo, Isabel, Bubb, Kristen J., Pearl, Vanessa, Milsom, Alexandra B., Khambata, Rayomand, Maleki-Toyserkani, Sheiva, Yousuf, Mubeen, Benjamin, Nigel et al. · 2013 · Hypertension
  81. Mediator‐induced activation of xanthine oxidase in endothelial cells
    Friedl, Hans P., Till, Gerd O., Ryan, Una S., Ward, Peter A. · 1989 · The FASEB Journal
  82. Neuronal Nitric Oxide Synthase Is Expressed in Rat Vascular Smooth Muscle Cells
    Chantal M. Boulanger, Christophe Heymes, Joëlle Bénessiano, Robert S. Geske, Bernard I Levy, Paul M. Vanhoutte · 1998 · Circulation Research
  83. Tetrahydrobiopterin Improves Endothelial Function in Patients with Coronary Artery Disease
    Maier, Willibald, Cosentino, Francesco, Lütolf, Roland B., Fleisch, Martin, Seiler, Christian, Hess, Otto M., Meier, Bernhard, Lüscher, Thomas F. · 2000 · Journal of Cardiovascular Pharmacology
  84. Proteomic identification of 3-nitrotyrosine-containing rat cardiac proteins: effects of biological aging
    Kanski, Jaroslaw, Behring, Antje, Pelling, Jill, Schöneich, Christian · 2005 · American Journal of Physiology-Heart and Circulatory Physiology
  85. The mechanism of conversion of rat liver xanthine dehydrogenase from an NAD+-dependent form (type D) to an O2-dependent form (type O)
    William R. Waud, K.V. Rajagopalan · 1976 · Archives of Biochemistry and Biophysics
  86. Sialin ( <i>SLC17A5</i> ) functions as a nitrate transporter in the plasma membrane
    Qin, Lizheng, Liu, Xibao, Sun, Qifei, Fan, Zhipeng, Xia, Dengsheng, Ding, Gang, Ong, Hwei Ling, Adams, David, Gahl, William A., Zheng, Changyu et al. · 2012 · Proceedings of the National Academy of Sciences
  87. Drug-Metabolizing Ability of Molybdenum Hydroxylases
    Kitamura, Shigeyuki, Sugihara, Kazumi, Ohta, Shigeru · 2006 · Drug Metabolism and Pharmacokinetics
  88. Dose-Dependent Regulation of NAD(P)H Oxidase Expression by Angiotensin II in Human Endothelial Cells: Protective Effect of Angiotensin II Type 1 Receptor Blockade in Patients With Coronary Artery Disease
    Rueckschloss, Uwe, Quinn, Mark T., Holtz, Juergen, Morawietz, Henning · 2002 · Arteriosclerosis, Thrombosis, and Vascular Biology
  89. Receptor-regulated Dynamic S-Nitrosylation of Endothelial Nitric-oxide Synthase in Vascular Endothelial Cells
    Phillip A. Erwin, Alison J. Lin, David E. Golan, Thomas M. Michel · 2005 · Journal of Biological Chemistry
  90. Deficient ryanodine receptor S -nitrosylation increases sarcoplasmic reticulum calcium leak and arrhythmogenesis in cardiomyocytes
    Daniel R. González, Farideh Beigi, Adriana V. Treuer, Joshua M. Hare · 2007 · Proceedings of the National Academy of Sciences
  91. Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia
    Adil Aziz Khan, Yaoming Wang, Yunjuan Sun, Xiao Ou Mao, Lin Xie, Erin Miles, Justin Graboski, Sylvia Chen, Lisa Ellerby, Kunlin Jin et al. · 2006 · Proceedings of the National Academy of Sciences
  92. Reversible Blockade of Electron Transport during Ischemia Protects Mitochondria and Decreases Myocardial Injury following Reperfusion
    Chen, Qun, Moghaddas, Shadi, Hoppel, Charles L., Lesnefsky, Edward J. · 2006 · The Journal of Pharmacology and Experimental Therapeutics
  93. Cytokine Activation of Nuclear Factor κB in Vascular Smooth Muscle Cells Requires Signaling Endosomes Containing Nox1 and ClC-3
    Francis J. Miller, Mohammed S. Filali, Gina J Huss, Bojana Stanić, Ali Chamseddine, Thomas J. Barna, Fred S. Lamb · 2007 · Circulation Research
  94. Nitrite reductase activity of cytochrome c
    Basu, Swati, Azarova, Natalia A., Font, Michael D., King, S. Bruce, Hogg, Neil, Gladwin, Mark T., Shiva, Sruti, Kim-Shapiro, Daniel B. · 2008 · Journal of Biological Chemistry
  95. Binding of human xanthine oxidase to sulphated glycosaminoglycans on the endothelial-cell surface
    T Adachi, Takeshi Fukushima, Yoshiko Usami, K Hirano · 1993 · Biochemical Journal
  96. Intramembrane Bis-Heme Motif for Transmembrane Electron Transport Conserved in a Yeast Iron Reductase and the Human NADPH Oxidase
    Finegold, Alan A., Shatwell, Karolyn P., Segal, Anthony W., Klausner, Richard D., Dancis, Andrew · 1996 · Journal of Biological Chemistry
  97. The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle
    ELLMARK, S, DUSTING, G, NGTANGFUI, M, GUZZOPERNELL, N, DRUMMOND, G · 2005 · Cardiovascular Research
  98. Leptin-induced endothelial dysfunction in obesity
    Korda, Mykhaylo, Kubant, Ruslan, Patton, Stephen, Malinski, Tadeusz · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
  99. Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
    Crabtree, Mark J., Smith, Caroline L., Lam, George, Goligorsky, Michael S., Gross, Steven S. · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
  100. Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation
    Aamand, Rasmus, Dalsgaard, Thomas, Jensen, Frank B., Simonsen, Ulf, Roepstorff, Andreas, Fago, Angela · 2009 · American Journal of Physiology-Heart and Circulatory Physiology
  101. Identification of Regulatory Sites of Phosphorylation of the Bovine Endothelial Nitric-oxide Synthase at Serine 617 and Serine 635
    Michell, Belinda J., Harris, M. Brennan, Chen, Zhi-ping, Ju, Hong, Venema, Virginia J., Blackstone, Michele A., Huang, Wei, Venema, Richard C., Kemp, Bruce E. · 2002 · Journal of Biological Chemistry
  102. Critical Role for Tetrahydrobiopterin Recycling by Dihydrofolate Reductase in Regulation of Endothelial Nitric-oxide Synthase Coupling
    Crabtree, Mark J., Tatham, Amy L., Hale, Ashley B., Alp, Nicholas J., Channon, Keith M. · 2009 · Journal of Biological Chemistry
  103. Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure
    Markus Follmann, Jens Ackerstaff, Gorden Redlich, Frank Wunder, Dieter H. Lang, Armin Kern, Peter Fey, Nils Griebenow, Walter Kroh, Eva‐Maria Becker‐Pelster et al. · 2017 · Journal of Medicinal Chemistry
  104. Novel Mechanism of Activation of NADPH Oxidase 5
    Jagnandan, Davin, Church, Jarrod E., Banfi, Botond, Stuehr, Dennis J., Marrero, Mario B., Fulton, David J.R. · 2007 · Journal of Biological Chemistry
  105. Angiotensin II Induces Endothelial Xanthine Oxidase Activation: Role for Endothelial Dysfunction in Patients With Coronary Disease
    Landmesser, Ulf, Spiekermann, Stephan, Preuss, Christoph, Sorrentino, Sajoscha, Fischer, Dieter, Manes, Costantina, Mueller, Maja, Drexler, Helmut · 2007 · Arteriosclerosis, Thrombosis, and Vascular Biology
  106. Characterization of Mitochondrial and Extra-mitochondrial Oxygen Consuming Reactions in Human Hematopoietic Stem Cells
    Piccoli, Claudia, Ria, Roberto, Scrima, Rosella, Cela, Olga, D'Aprile, Annamaria, Boffoli, Domenico, Falzetti, Franca, Tabilio, Antonio, Capitanio, Nazzareno · 2005 · Journal of Biological Chemistry
  107. The Promise and Perils of Antioxidants for Cancer Patients
    Navdeep S. Chandel, David Arthur Tuveson · 2014 · New England Journal of Medicine
  108. Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction
    Wenzel, Philip, Schuhmacher, Swenja, Kienhöfer, Joachim, Müller, Johanna, Hortmann, Marcus, Oelze, Matthias, Schulz, Eberhard, Treiber, Nicolai, Kawamoto, Toshihiro, Scharffetter-Kochanek, Karin et al. · 2008 · Cardiovascular Research
  109. Critical Role of the NAD(P)H Oxidase Subunit p47 <sup> <i>phox</i> </sup> for Left Ventricular Remodeling/Dysfunction and Survival After Myocardial Infarction
    Doerries, Carola, Grote, Karsten, Hilfiker-Kleiner, Denise, Luchtefeld, Maren, Schaefer, Arnd, Holland, Steven M., Sorrentino, Sajoscha, Manes, Costantina, Schieffer, Bernhard, Drexler, Helmut et al. · 2007 · Circulation Research
  110. Protein <i>S</i> -Nitrosylation and Cardioprotection
    Sun, Junhui, Murphy, Elizabeth · 2010 · Circulation Research
  111. Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor
    Hirano, Kazufumi, Chen, Woei Shin, Chueng, Adeline L.W., Dunne, Angela A., Seredenina, Tamara, Filippova, Aleksandra, Ramachandran, Sumitra, Bridges, Angela, Chaudry, Laiq, Pettman, Gary et al. · 2015 · Antioxidants &amp; Redox Signaling
  112. Supplemention With Tetrahydrobiopterin Suppresses the Development of Hypertension in Spontaneously Hypertensive Rats
    Hong, Hong-Jye, Hsiao, George, Cheng, Tzu-Hurng, Yen, Mao-Hsiung · 2001 · Hypertension
  113. Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia: Role for Xanthine Oxidoreductase and Endothelial Nitric Oxide Synthase
    Webb, Andrew J., Milsom, Alexandra B., Rathod, Krishnaraj S., Chu, Wai Lum, Qureshi, Shehla, Lovell, Matthew J., Lecomte, Florence M.J., Perrett, David, Raimondo, Carmelo, Khoshbin, Espeed et al. · 2008 · Circulation Research
  114. Rapid and Irreversible Inactivation of Protein Tyrosine Phosphatases PTP1B, CD45, and LAR by Peroxynitrite
    Ko Takakura, Joseph S. Beckman, Lee Ann MacMillan-Crow, John P. Crow · 1999 · Archives of Biochemistry and Biophysics
  115. Protection against renal ischemia–reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ
    Dare, Anna J., Bolton, Eleanor A., Pettigrew, Gavin J., Bradley, J. Andrew, Saeb-Parsy, Kourosh, Murphy, Michael P. · 2015 · Redox Biology
  116. Classical Inhibitors of NOX NAD(P)H Oxidases Are Not Specific
    Aldieri, Elisabetta, Riganti, Chiara, Polimeni, Manuela, Gazzano, Elena, Lussiana, Cristina, Campia, Ivana, Ghigo, Dario · 2008 · Current Drug Metabolism
  117. Red cell membrane and plasma linoleic acid nitration products: Synthesis, clinical identification, and quantitation
    Baker, Paul R. S., Schopfer, Francisco J., Sweeney, Scott, Freeman, Bruce A. · 2004 · Proceedings of the National Academy of Sciences
  118. Quantitative Regulation of Intracellular Endothelial Nitric-oxide Synthase (eNOS) Coupling by Both Tetrahydrobiopterin-eNOS Stoichiometry and Biopterin Redox Status
    Crabtree, Mark J., Tatham, Amy L., Al-Wakeel, Yasir, Warrick, Nicholas, Hale, Ashley B., Cai, Shijie, Channon, Keith M., Alp, Nicholas J. · 2009 · Journal of Biological Chemistry
  119. Nitro-fatty Acid Reaction with Glutathione and Cysteine
    Baker, Laura M.S., Baker, Paul R.S., Golin-Bisello, Franca, Schopfer, Francisco J., Fink, Mitchell, Woodcock, Steven R., Branchaud, Bruce P., Radi, Rafael, Freeman, Bruce A. · 2007 · Journal of Biological Chemistry
  120. Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: An experimental-computational study
    Aon, Miguel Antonio, Stanley, Brian Alan, Sivakumaran, Vidhya, Kembro, Jackelyn Melissa, O'Rourke, Brian, Paolocci, Nazareno, Cortassa, Sonia · 2012 · Journal of General Physiology
  121. The Chemistry and Biology of Soluble Guanylate Cyclase Stimulators and Activators
    Follmann, Markus, Griebenow, Nils, Hahn, Michael G., Hartung, Ingo, Mais, Franz‐Josef, Mittendorf, Joachim, Schäfer, Martina, Schirok, Hartmut, Stasch, Johannes‐Peter, Stoll, Friederike et al. · 2013 · Angewandte Chemie International Edition
  122. Attenuation of Myocardial Ischemia/Reperfusion Injury by Superinduction of Inducible Nitric Oxide Synthase
    Shinichi Kanno, Paul C. Lee, Yuqing Zhang, Chien Ho, Bartley P. Griffith, Larry L. Shears, Timothy R. Billiar · 2000 · Circulation
  123. Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics
    DEZFULIAN, C, RAAT, N, SHIVA, S, GLADWIN, M · 2007 · Cardiovascular Research
  124. The carbonate radical and related oxidants derived from bicarbonate buffer
    Medinas, Danilo B., Cerchiaro, Giselle, Trindade, Daniel F., Augusto, Ohara · 2007 · IUBMB Life
  125. Increased Reactive Oxygen Species Production and Functional Alterations in Antioxidant Enzymes in Human Failing Myocardium
    Flora Sam, David L. Kerstetter, David R. Pimental, Suresh R Mulukutla, Arash Tabaee, Michael R. Bristow, Wilson S. Colucci, Douglas B. Sawyer · 2005 · Journal of Cardiac Failure
  126. Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease
    Tim S. Schmidt, Nicholas J. Alp · 2007 · Clinical Science
  127. Flavanols and cardiovascular disease prevention
    Christian Heiß, Carl L. Keen, Malte Kelm · 2010 · European Heart Journal
  128. Direct Evidence for Nitric Oxide Production by a Nitric-oxide Synthase-like Protein from Bacillus subtilis
    Adak, Subrata, Aulak, Kulwant S., Stuehr, Dennis J. · 2002 · Journal of Biological Chemistry
  129. Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products
    Biao, Xu, Chibber, Rakesh, Ruggiero, Daniel, Kohner, Eva, Ritter, James, Ferro, Albert · 2003 · The FASEB Journal
  130. IV. Determinants of nitric oxide protection and toxicity in liver
    Li, Jianrong, Billiar, Timothy R. · 1999 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  131. The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase
    Gladwin, Mark T., Grubina, Rozalina, Doyle, Michael P. · 2009 · Accounts of Chemical Research
  132. Beneficial effects of α-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress
    Heitzer, T · 2001 · Free Radical Biology and Medicine
  133. Increased Endothelial Tetrahydrobiopterin Synthesis by Targeted Transgenic GTP-Cyclohydrolase I Overexpression Reduces Endothelial Dysfunction and Atherosclerosis in ApoE-Knockout Mice
    Alp, Nicholas J., McAteer, Martina A., Khoo, Jeffrey, Choudhury, Robin P., Channon, Keith M. · 2004 · Arteriosclerosis, Thrombosis, and Vascular Biology
  134. Expression of constitutive endothelial nitric oxide synthase in human blood platelets
    Kazuhiro Sase, Thomas M. Michel · 1995 · Life Sciences
  135. Neuronal Nitric Oxide Synthase Self-inactivates by Forming a Ferrous-Nitrosyl Complex during Aerobic Catalysis
    Husam M. Abu‐Soud, Jianling Wang, Denis L. Rousseau, Jon M. Fukuto, Louis Joseph Ignarro, Dennis J. Stuehr · 1995 · Journal of Biological Chemistry
  136. Iron and copper toxicity in diseases of aging, particularly atherosclerosis and Alzheimer's disease.
    George J. Brewer · 2007 · PubMed
  137. A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells
    Gianni, Davide, Taulet, Nicolas, Zhang, Hui, DerMardirossian, Celine, Kister, Jeremy, Martinez, Luis, Roush, William R., Brown, Steven J., Bokoch, Gary M., Rosen, Hugh · 2010 · ACS Chemical Biology
  138. Myocardial ischemia results in tetrahydrobiopterin (BH <sub>4</sub> ) oxidation with impaired endothelial function ameliorated by BH <sub>4</sub>
    Dumitrescu, Cristian, Biondi, Roberto, Xia, Yong, Cardounel, Arturo J., Druhan, Lawrence J., Ambrosio, Giuseppe, Zweier, Jay L. · 2007 · Proceedings of the National Academy of Sciences
  139. Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation
    Zuckerbraun, Brian S., Shiva, Sruti, Ifedigbo, Emeka, Mathier, Michael A., Mollen, Kevin P., Rao, Jayashree, Bauer, Philip M., Choi, Justin J.W., Curtis, Erin, Choi, Augustine M.K. et al. · 2010 · Circulation
  140. Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2
    Wang, W · 2002 · Cardiovascular Research
  141. Mechanism of Superoxide Generation by Neuronal Nitric-oxide Synthase
    Sovitj Pou, Lori Keaton, Wanida Surichamorn, Gerald M. Rosen · 1999 · Journal of Biological Chemistry
  142. O 2 sensing, mitochondria and ROS signaling: The fog is lifting
    Gregory B. Waypa, Kimberly A. Smith, Paul T. Schumacker · 2016 · Molecular Aspects of Medicine
  143. Discovery of Riociguat (BAY 63‐2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension
    Joachim Mittendorf, Stefan Weigand, Cristina Alonso‐Alija, Erwin Bischoff, Achim Feurer, Michael Gerisch, Armin Kern, Andreas Knorr, Dieter H. Lang, Klaus Muenter et al. · 2009 · ChemMedChem
  144. Xanthine Oxidase
    Irwin Fridovich, Philip Handler · 1962 · Journal of Biological Chemistry
  145. Lipopolysaccharide Stimulates Mitochondrial Biogenesis via Activation of Nuclear Respiratory Factor-1
    Suliman, Hagir B., Carraway, Martha S., Welty-Wolf, Karen E., Whorton, A.Richard, Piantadosi, Claude A. · 2003 · Journal of Biological Chemistry
  146. Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling
    Gray, Stephen P., Di Marco, Elyse, Kennedy, Kit, Chew, Phyllis, Okabe, Jun, El-Osta, Assam, Calkin, Anna C., Biessen, Erik A.L., Touyz, Rhian M., Cooper, Mark E. et al. · 2016 · Arteriosclerosis, Thrombosis, and Vascular Biology
  147. Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 Is Mediated via Calcium/Calmodulin-Dependent, Rac-1-Independent Pathways in Human Endothelial Cells
    Montezano, Augusto C., Burger, Dylan, Paravicini, Tamara M., Chignalia, Andreia Z., Yusuf, Hiba, Almasri, Mahmoud, He, Ying, Callera, Glaucia E., He, Gang, Krause, Karl-Heinz et al. · 2010 · Circulation Research
  148. Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion
    Rudolph, Volker, Rudolph, Tanja K., Schopfer, Francisco J., Bonacci, Gustavo, Woodcock, Steven R., Cole, Marsha P., Baker, Paul R.S., Ramani, Ravi, Freeman, Bruce A. · 2010 · Cardiovascular Research
  149. Crystal structures and atomic model of NADPH oxidase
    Francesca Magnani, S. Nenci, Elisa Millana Fañanás, Marta Ceccon, Elvira Romero, Marco W. Fraaije, Andrea Mattevi · 2017 · Proceedings of the National Academy of Sciences
  150. Link between Mitochondria and NADPH Oxidase 1 Isozyme for the Sustained Production of Reactive Oxygen Species and Cell Death
    Lee, Seung Bum, Bae, In Hwa, Bae, Yun Soo, Um, Hong-Duck · 2006 · Journal of Biological Chemistry
  151. The red blood cell as an oxygen sensor: what is the evidence?
    Ellsworth, M.L. · 2000 · Acta Physiologica Scandinavica
  152. Red wine-dependent reduction of nitrite to nitric oxide in the stomach
    Gago, Bruno, Lundberg, Jon O., Barbosa, Rui M., Laranjinha, João · 2007 · Free Radical Biology and Medicine
  153. Kinetics of Cytochrome C2+ Oxidation by Peroxynitrite: Implications for Superoxide Measurements in Nitric Oxide-Producing Biological-Systems
    Thomson, L., Trujillo, M., Telleri, R., Radi, R. · 1995 · Archives of Biochemistry and Biophysics
  154. Enhanced Release of Prostaglandins Contributes to Flow-Induced Arteriolar Dilation in eNOS Knockout Mice
    Sun, Dong, Huang, An, Smith, Carolyn J., Stackpole, Christopher J., Connetta, Joseph A., Shesely, Edward G., Koller, Akos, Kaley, Gabor · 1999 · Circulation Research
  155. Arginase Inhibition Improves Endothelial Function in Patients With Coronary Artery Disease and Type 2 Diabetes Mellitus
    Alexey S. Shemyakin, Oskar Kövamees, Arnar Thor Rafnsson, Felix Böhm, Peter K. Svenarud, Magnus Settergren, Christian Jung, John Pernow · 2012 · Circulation
  156. Nitric oxide, a protective molecule in the cardiovascular system
    Lei, Jing, Vodovotz, Yoram, Tzeng, Edith, Billiar, Timothy R. · 2013 · Nitric Oxide
  157. Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease
    Cortese-Krott, Miriam M., Rodriguez-Mateos, Ana, Sansone, Roberto, Kuhnle, Gunter G. C., Thasian-Sivarajah, Sivatharsini, Krenz, Thomas, Horn, Patrick, Krisp, Christoph, Wolters, Dirk, Heiß, Christian et al. · 2012 · Blood
  158. Rate constant for reaction of hydroxyl radicals with bicarbonate ions
    Buxton, George V., Elliot, Allen John · 1986 · International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry
  159. Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase
    SPALLAROSSA, P, ALTIERI, P, GARIBALDI, S, GHIGLIOTTI, G, BARISIONE, C, MANCA, V, FABBI, P, BALLESTRERO, A, BRUNELLI, C, BARSOTTI, A · 2006 · Cardiovascular Research
  160. Electron transfer by diflavin reductases
    Marat B. Murataliev, René Feyereisen, F. Ann Walker · 2003 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  161. Xanthine Oxidase Inhibition by Febuxostat Attenuates Experimental Atherosclerosis in Mice
    Nomura, Johji, Busso, Nathalie, Ives, Annette, Matsui, Chieko, Tsujimoto, Syunsuke, Shirakura, Takashi, Tamura, Mizuho, Kobayashi, Tsunefumi, So, Alexander, Yamanaka, Yoshihiro · 2014 · Scientific Reports
  162. Oxidative Stress and Endothelial Dysfunction in Aortas of Aged Spontaneously Hypertensive Rats by NOX1/2 Is Reversed by NADPH Oxidase Inhibition
    Wind, Sven, Beuerlein, Knut, Armitage, Melanie E., Taye, Ashraf, Kumar, Arun H.S., Janowitz, Daniel, Neff, Christina, Shah, Ajay M., Wingler, Kirstin, Schmidt, Harald H.H.W. · 2010 · Hypertension
  163. Flavohemoglobin Detoxifies Nitric Oxide in Aerobic, but Not Anaerobic, Escherichia coli
    Anne M. Gardner, Paul R. Gardner · 2002 · Journal of Biological Chemistry
  164. Xanthine oxidoreductase in atherosclerosis pathogenesis: Not only oxidative stress
    Battelli, Maria Giulia, Polito, Letizia, Bolognesi, Andrea · 2014 · Atherosclerosis
  165. An NAD(P)H oxidase regulates growth and transcription in melanoma cells
    Sukhdev S. Brar, Thomas P. Kennedy, Anne Sturrock, Thomas P. Huecksteadt, Mark T. Quinn, A. Richard Whorton, John R. Hoidal · 2002 · American Journal of Physiology-Cell Physiology
  166. The NADPH oxidase Nox4 has anti-atherosclerotic functions
    Christoph Schürmann, Flávia Rezende, Christoph Kruse, Yakub Yasar, Oliver Löwe, Christian Fork, Bart van de Sluis, Rolf Bremer, Norbert Weißmann, Ajay M. Shah et al. · 2015 · European Heart Journal
  167. Folic Acid Prevents Nitroglycerin-Induced Nitric Oxide Synthase Dysfunction and Nitrate Tolerance: A Human In Vivo Study
    Gori, Tommaso, Burstein, Jason M., Ahmed, Sofia, Miner, Steve E.S., Al-Hesayen, Abdul, Kelly, Susan, Parker, John D. · 2001 · Circulation
  168. NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-β1 and insulin-like growth factor binding protein-3
    Ismail, Saleh, Sturrock, Anne, Wu, Ping, Cahill, Barbara, Norman, Kimberly, Huecksteadt, Thomas, Sanders, Karl, Kennedy, Thomas, Hoidal, John · 2009 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  169. Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome
    Oller, Jorge, Méndez-Barbero, Nerea, Ruiz, E Josue, Villahoz, Silvia, Renard, Marjolijn, Canelas, Lizet I, Briones, Ana M, Alberca, Rut, Lozano-Vidal, Noelia, Hurlé, María A et al. · 2017 · Nature Medicine
  170. Nitrite Anion Provides Potent Cytoprotective and Antiapoptotic Effects as Adjunctive Therapy to Reperfusion for Acute Myocardial Infarction
    Gonzalez, Felix M., Shiva, Sruti, Vincent, Pamela S., Ringwood, Lorna A., Hsu, Li-Yueh, Hon, Yuen Yi, Aletras, Anthony H., Cannon, Richard O., Gladwin, Mark T., Arai, Andrew E. · 2008 · Circulation
  171. Tetrahydrobiopterin Radical Enzymology
    Wei, Chin-Chuan, Crane, Brian R., Stuehr, Dennis J. · 2003 · Chemical Reviews
  172. The role of aldehyde oxidase in drug metabolism
    Garattini, Enrico, Terao, Mineko · 2012 · Expert Opinion on Drug Metabolism &amp; Toxicology
  173. Superoxide-forming enzyme from human neutrophils: Evidence for a flavin requirement
    Babior, BM, Kipnes, RS · 1977 · Blood
  174. Phosphorylation of Endothelial Nitric-oxide Synthase Regulates Superoxide Generation from the Enzyme
    Chun‐An Chen, Lawrence J. Druhan, Saradhadevi Varadharaj, Yeong‐Renn Chen, Jay Louis Zweier · 2008 · Journal of Biological Chemistry
  175. Effects of the soluble guanylyl cyclase activator, YC‐1, on vascular tone, cyclic GMP levels and phosphodiesterase activity
    Jan Galle, Ulrike Zabel, Ulrich Hübner, Armin Hatzelmann, Birgit Wagner, Christoph Wanner, Harald H.H.W. Schmidt · 1999 · British Journal of Pharmacology
  176. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
    Higashi, Y., Sasaki, S., Nakagawa, K., Fukuda, Y., Matsuura, H., Oshima, T., Chayama, K. · 2002 · American Journal of Hypertension
  177. Atherosclerosis Is Attenuated by Limiting Superoxide Generation in Both Macrophages and Vessel Wall Cells
    Vendrov, Aleksandr E., Hakim, Zeenat S., Madamanchi, Nageswara R., Rojas, Mauricio, Madamanchi, Chaitanya, Runge, Marschall S. · 2007 · Arteriosclerosis, Thrombosis, and Vascular Biology
  178. Glucocorticoids Increase Osteopontin Expression in Cardiac Myocytes and Microvascular Endothelial Cells
    Krishna Singh, Jean‐Luc Balligand, Thomas A. Fischer, Thomas Wayne Smith, Ralph A. Kelly · 1995 · Journal of Biological Chemistry
  179. The eNOS signalosome and its link to endothelial dysfunction
    Mauro Siragusa, Ingrid Fleming · 2016 · Pflügers Archiv - European Journal of Physiology
  180. Impaired Superoxide Production Due to a Deficiency in Phagocyte NADPH Oxidase Fails to Inhibit Atherosclerosis in Mice
    Kirk, Elizabeth A., Dinauer, Mary C., Rosen, Henry, Chait, Alan, Heinecke, Jay W., LeBoeuf, Renée C. · 2000 · Arteriosclerosis, Thrombosis, and Vascular Biology
  181. The peroxidase–cyclooxygenase superfamily: Reconstructed evolution of critical enzymes of the innate immune system
    Zamocky, Marcel, Jakopitsch, Christa, Furtmüller, Paul G., Dunand, Christophe, Obinger, Christian · 2008 · Proteins: Structure, Function, and Bioinformatics
  182. Nitrite Reductase and Nitric-oxide Synthase Activity of the Mitochondrial Molybdopterin Enzymes mARC1 and mARC2
    Courtney E. Sparacino-Watkins, Jesús Tejero, Bin Sun, Marc C. Gauthier, John Thomas, Venkata Ragireddy, Bonnie A. Merchant, Jun Wang, Ivan Azarov, Partha Basu et al. · 2014 · Journal of Biological Chemistry
  183. NOX5 in Human Spermatozoa
    Boris Musset, Robert A. Clark, Thomas E. DeCoursey, Gábor L. Petheö, Miklós Geiszt, Yumin Chen, John E. Cornell, Carlton A. Eddy, Robert G. Brzyski, Amina El Jamali · 2012 · Journal of Biological Chemistry
  184. Molecular recognition of nitrated fatty acids by PPARγ
    Li, Yong, Zhang, Jifeng, Schopfer, Francisco J, Martynowski, Dariusz, Garcia-Barrio, Minerva T, Kovach, Amanda, Suino-Powell, Kelly, Baker, Paul R S, Freeman, Bruce A, Chen, Y Eugene et al. · 2008 · Nature Structural &amp; Molecular Biology
  185. ROS signaling and redox biology in endothelial cells
    Panieri, Emiliano, Santoro, Massimo M. · 2015 · Cellular and Molecular Life Sciences
  186. YC-1 Potentiates Nitric Oxide- and Carbon Monoxide-Induced Cyclic GMP Effects in Human Platelets
    Andreas Friebe, Florian Müllershausen, Albert Smolenski, Ulrich Walter, Günter Schultz, Doris Koesling · 1998 · Molecular Pharmacology
  187. Systemic and Vascular Oxidation Limits the Efficacy of Oral Tetrahydrobiopterin Treatment in Patients With Coronary Artery Disease
    Cunnington, Colin, Van Assche, Tim, Shirodaria, Cheerag, Kylintireas, Ilias, Lindsay, Alistair C., Lee, Justin M., Antoniades, Charalambos, Margaritis, Marios, Lee, Regent, Cerrato, Ruha et al. · 2012 · Circulation
  188. Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells
    Jay, Desmond B., Papaharalambus, Christopher A., Seidel-Rogol, Bonnie, Dikalova, Anna E, Lassègue, Bernard, Griendling, Kathy K. · 2008 · Free Radical Biology and Medicine
  189. Erythrocytes and Vascular Function: Oxygen and Nitric Oxide
    Christine Carlisle Helms, Mark T. Gladwin, Daniel B. Kim‐Shapiro · 2018 · Frontiers in Physiology
  190. Carbon Monoxide and Bilirubin
    Stefan W. Ryter, Danielle Morse, Augustine M.K. Choi · 2006 · American Journal of Respiratory Cell and Molecular Biology
  191. Xanthine Oxidase Inhibition For The Treatment Of Cardiovascular Disease: A Systematic Review and Meta‐Analysis
    Higgins, Peter, Dawson, Jesse, Lees, Kennedy R., McArthur, Kate, Quinn, Terrence J., Walters, Matthew R. · 2012 · Cardiovascular Therapeutics
  192. Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis: Implications for impaired vasomotion
    Harrison, David G., Ohara, Yuichi · 1995 · The American Journal of Cardiology
  193. ROS-induced ROS release in vascular biology: redox-redox signaling
    Zinkevich, Natalya S., Gutterman, David D. · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
  194. Receptor Activation of NADPH Oxidases
    Petry, Andreas, Weitnauer, Michael, Görlach, Agnes · 2010 · Antioxidants &amp; Redox Signaling
  195. Phosphoinositide-Dependent Kinase 1 and p21-Activated Protein Kinase Mediate Reactive Oxygen Species–Dependent Regulation of Platelet-Derived Growth Factor–Induced Smooth Muscle Cell Migration
    David S. Weber, Yoshihiro Taniyama, Petra Ročić, Puvi Seshiah, Melissa A. Dechert, William T. Gerthoffer, Kathy K. Griendling · 2004 · Circulation Research
  196. EMBRACE STEMI study: a Phase 2a trial to evaluate the safety, tolerability, and efficacy of intravenous MTP-131 on reperfusion injury in patients undergoing primary percutaneous coronary intervention
    Gibson, C. Michael, Giugliano, Robert P., Kloner, Robert A., Bode, Christoph, Tendera, Michal, Jánosi, András, Merkely, Bela, Godlewski, Jacek, Halaby, Rim, Korjian, Serge et al. · 2016 · European Heart Journal
  197. Asymmetric Dimethylarginine and Cardiovascular Risk: Systematic Review and Meta‐Analysis of 22 Prospective Studies
    Peter Willeit, Daniel F. Freitag, Jari Antero Laukkanen, Susmita Chowdhury, Reeta Gobin, Manuel Mayr, Emanuele Di Angelantonio, Rajiv Chowdhury · 2015 · Journal of the American Heart Association
  198. L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits.
    Rossitch, E, Alexander, E, Black, P M, Cooke, J P · 1991 · Journal of Clinical Investigation
  199. Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain
    Nisimoto, Yukio, Jackson, Heather M., Ogawa, Hisamitsu, Kawahara, Tsukasa, Lambeth, J. David · 2010 · Biochemistry
  200. Sites and Mechanisms of Aconitase Inactivation by Peroxynitrite:  Modulation by Citrate and Glutathione
    Han, Derick, Canali, Raffaella, Garcia, Jerome, Aguilera, Rodrigo, Gallaher, Timothy K., Cadenas, Enrique · 2005 · Biochemistry