Stem Cells and the Differentiation Hierarchy in Mammary Gland Development

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Generation of a functional mammary gland from a single stem cell

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Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

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Mapping the Mouse Cell Atlas by Microwell-Seq

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Purification and unique properties of mammary epithelial stem cells

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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

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Cells of origin in cancer

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Molecular Definition of Breast Tumor Heterogeneity

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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

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Hedgehog Signaling and Bmi-1 Regulate Self-renewal of Normal and Malignant Human Mammary Stem Cells

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Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice.

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Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

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Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

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Hematopoietic stem cell: self‐renewal versus differentiation

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The Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate

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Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

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Distinct stem cells contribute to mammary gland development and maintenance

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Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

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Reconstruction of functionally normal and malignant human breast tissues in mice

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BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

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The osteoclast differentiation factor osteoprotegerin ligand is essential for mammary gland development.

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The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

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Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

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Control of mammary stem cell function by steroid hormone signalling

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Progesterone induces adult mammary stem cell expansion

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GATA-3 Maintains the Differentiation of the Luminal Cell Fate in the Mammary Gland

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Tetraspanins: push and pull in suppressing and promoting metastasis

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The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength

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Transient Increase in the Risk of Breast Cancer after Giving Birth

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Replacement of lost Lgr5-positive stem cells through plasticity of their enterocyte-lineage daughters

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An entire functional mammary gland may comprise the progeny from a single cell

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Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform

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In situ identification of bipotent stem cells in the mammary gland

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Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling

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A paracrine role for the epithelial progesterone receptor in mammary gland development

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Postnatal mammary gland development requires macrophages and eosinophils

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Mammary ductal elongation: Differentiation of myoepithelium and basal lamina during branching morphogenesis

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BRCA1 regulates human mammary stem/progenitor cell fate

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Hormone Action in the Mammary Gland

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Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland

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Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment

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Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

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Paracrine signaling through the epithelial estrogen receptor α is required for proliferation and morphogenesis in the mammary gland

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Evidence for a stem cell hierarchy in the adult human breast

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Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

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Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

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Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties

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Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis!

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Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity

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Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing

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Mesenchyme-Dependent Morphogenesis and Epithelium-Specific Cytodifferentiation in Mouse Mammary Gland

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Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity

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Causes and Consequences of Hematopoietic Stem Cell Heterogeneity

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A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability

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PIK3CAH1047R induces multipotency and multi-lineage mammary tumours

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A putative human breast stem cell population is enriched for steroid receptor-positive cells

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Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland

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CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells

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Amphiregulin is an essential mediator of estrogen receptor α function in mammary gland development

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The Role of the Microenvironment in Mammary Gland Development and Cancer

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Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin

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RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers

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Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland

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Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland

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Hormonal and local control of mammary branching morphogenesis

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Steroid Hormone Receptor Status of Mouse Mammary Stem Cells

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Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands

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The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study.

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Enhancing the precision of genetic lineage tracing using dual recombinases

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The Ets transcription factor Elf5 specifies mammary alveolar cell fate

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DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

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A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland

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FOXA1 is an essential determinant of ERα expression and mammary ductal morphogenesis

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Mammary stem cells have myoepithelial cell properties

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A Mammary Stem Cell Population Identified and Characterized in Late Embryogenesis Reveals Similarities to Human Breast Cancer

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