Motor Memory Consolidation in Sleep Shapes More Effective Neuronal Representations
Open accessAbstract
Learning a motor skill involves a latent process of consolidation that develops after training to enhance the skill in the absence of any practice and crucially depends on sleep. Here, we show that this latent consolidation during sleep changes the brain representation of the motor skill by reducing overall the neocortical contributions to the representation. Functional magnetic resonance brain imaging was performed during initial training and 48 h later, at retesting, on a sequential finger movement task with training followed by either a night of regular sleep or sleep deprivation. An additional night of sleep for all subjects served to rule out unspecific effects of sleep loss at retrieval testing. Posttraining sleep, but not sleep deprivation, led to improved motor skill performance at retrieval. This sleep-dependent improvement was linked to greatly reduced brain activation in prefrontal, premotor, and primary motor cortical areas, along with a stronger involvement of left parietal cortical regions. Our findings indicate that storing a motor skill during sleep reorganizes its brain representation toward enhanced efficacy.
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Sleep-dependent changes in brain activity indicative of reorganization of memory representations have been reported for procedural tasks like sequence finger tapping and visual texture discrimination.
“Finally, sleep-dependent changes in brain activity indicative for a reorganization of memory representations have also been reported for procedural tasks like sequences finger tapping and visual texture discrimination (384, 1292, 1293).”
From About Sleep's Role in Memory (2013) · cites this paper as [384]
The Discussion (Fig. 3) reports sleep-related changes in brain activity during retrieval of a finger-tapping sequence, supporting that example of the claim. The paper’s finger-sequence tapping task section describes its experiments, but the passages found do not report brain-activity changes for visual texture discrimination. (LLM, conf=0.87)
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The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900 · see citing works
Rechtschaffen, A. (1968) · Medical Entomology and Zoology · Cited by 11,772 · see citing works
Memory - A century of consolidation
McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250 · see citing works
An internal model for sensorimotor integration
Wolpert, D. M., Ghahramani, Z., & Jordan, M. I. (1995) · Science · doi:10.1126/science.7569931 · Cited by 3,553 · see citing works
Increased Cortical Representation of the Fingers of the Left Hand in String Players
Elbert, T. R., Pantev, C., Wienbruch, C., Rockstroh, B. S., & Taub, E. (1995) · Science · doi:10.1126/science.270.5234.305 · Cited by 2,053 · see citing works
Functional MRI evidence for adult motor cortex plasticity during motor skill learning
Kami, A., Meyer, G., Jezzard, P., Adams, M. M., Turner, R., & Ungerleider, L. G. (1995) · Nature · doi:10.1038/377155a0 · Cited by 1,883 · see citing works
Karni, A., Meyer, G., Rey-Hipolito, C., Jezzard, P., Adams, M. M., Turner, R., & Ungerleider, L. G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.3.861 · Cited by 1,387 · see citing works
Practice with Sleep Makes Perfect
Walker, M. P., Brakefield, T., Morgan, A., Hobson, J. A., & Stickgold, R. (2002) · Neuron · doi:10.1016/s0896-6273(02)00746-8 · Cited by 1,307 · see citing works
Motor sequence learning: a study with positron emission tomography
Jenkins, I., Brooks, D. J., Nixon, P., Frackowiak, R. S. J., & Passingham, R. E. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-06-03775.1994 · Cited by 1,201 · see citing works
The role of sleep in learning and memory
Maquet, P. (2001) · Science · doi:10.1126/science.1062856 · Cited by 1,177 · see citing works
The Basal Ganglia and Chunking of Action Repertoires
Graybiel, A. M. (1998) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1998.3843 · Cited by 1,042 · see citing works
Dissociable stages of human memory consolidation and reconsolidation
Walker, M. P., Brakefield, T., Allan Hobson, J., & Stickgold, R. (2003) · Nature · doi:10.1038/nature01930 · Cited by 1,025 · see citing works
Neural Correlates of Motor Memory Consolidation
Shadmehr, R., & Holcomb, H. H. (1997) · Science · doi:10.1126/science.277.5327.821 · Cited by 1,022 · see citing works
Wagner, U., Gais, S., Haider, H., Verleger, R., & Born, J. (2004) · Nature · doi:10.1038/nature02223 · Cited by 1,012 · see citing works
Functional Magnetic Resonance Imaging of Motor Cortex: Hemispheric Asymmetry and Handedness
Kim, S., Ashe, J., Hendrich, K. S., Ellermann, J., Merkle, H., Uǧurbil, K., & Georgopoulos, A. P. (1993) · Science · doi:10.1126/science.8342027 · Cited by 984 · see citing works
Prefrontal–cingulate interactions in action monitoring
Gehring, W. J., & Knight, R. T. (2000) · Nature Neuroscience · doi:10.1038/74899 · Cited by 912 · see citing works
Hori, T., Sugita, Y., Koga, E., Shirakawa, S., Inoue, K., Uchida, S., Kuwahara, H., Kousaka, M., Kobayashi, T., Tsuji, Y., et al. (2001) · Psychiatry and Clinical Neurosciences · doi:10.1046/j.1440-1819.2001.00810.x · Cited by 811 · see citing works
Parallel neural networks for learning sequential procedures
Hikosaka, O., Nakahara, H., Rand, M. K., Sakai, K., Lu, X., Nakamura, K., Miyachi, S., & Doya, K. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(99)01439-3 · Cited by 799 · see citing works
The time course of learning a visual skill
Karni, A., & Sagi, D. (1993) · Nature · doi:10.1038/365250a0 · Cited by 792 · see citing works
Experience-dependent changes in cerebral activation during human REM sleep
Maquet, P., Laureys, S., Peigneux, P., Fuchs, S., Petiau, C., Phillips, C., Aerts, J., Del Fiore, G., Degueldre, C., Meulemans, T., et al. (2000) · Nature Neuroscience · doi:10.1038/77744 · Cited by 747 · see citing works
Visual discrimination learning requires sleep after training
Stickgold, R., James, L., & Hobson, J. A. (2000) · Nature Neuroscience · doi:10.1038/81756 · Cited by 715 · see citing works
Imaging brain plasticity during motor skill learning
Ungerleider, L. (2002) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2002.4091 · Cited by 641 · see citing works
Anatomy of motor learning. I. Frontal cortex and attention to action
Jueptner, M., Stephan, K. M., Frith, C. D., Brooks, D. J., Frackowiak, R. S. J., & Passingham, R. E. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.77.3.1313 · Cited by 624 · see citing works
Sleep forms memory for finger skills
Fischer, S., Hallschmid, M., Elsner, A. L., & Born, J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182178199 · Cited by 589 · see citing works
Self-citationFriston, K. J., Penny, W. D., & Glaser, D. E. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.01.013 · Cited by 578 · see citing works
Early sleep triggers memory for early visual discrimination skills
Gais, S., Plihal, W., Wagner, U., & Born, J. (2000) · Nature Neuroscience · doi:10.1038/81881 · Cited by 558 · see citing works
Altered brain response to verbal learning following sleep deprivation
Drummond, S. P. A., Brown, G. G., Gillin, J. C., Stricker, J. L., Wong, E. C., & Buxton, R. B. (2000) · Nature · doi:10.1038/35001068 · Cited by 557 · see citing works
Anatomy of Motor Learning. II. Subcortical Structures and Learning by Trial and Error
Jueptner, M., Frith, C., Brooks, D. J., Frackowiak, R. S. J., & Passingham, R. E. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.77.3.1325 · Cited by 466 · see citing works
A refined model of sleep and the time course of memory formation
Walker, M. P. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000026 · Cited by 466 · see citing works
Transition of Brain Activation from Frontal to Parietal Areas in Visuomotor Sequence Learning
Sakai, K., Hikosaka, O., Miyauchi, S., Takino, R., Sasaki, Y., & Pütz, B. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-05-01827.1998 · Cited by 465 · see citing works
Deiber, M., Honda, M., Ibañez, V., Sadato, N., & Hallett, M. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.81.6.3065 · Cited by 425 · see citing works
The Time Course of Changes during Motor Sequence Learning: A Whole-Brain fMRI Study
Toni, I., Krams, M., Turner, R., & Passingham, R. E. (1998) · NeuroImage · doi:10.1006/nimg.1998.0349 · Cited by 411 · see citing works
Korman, M., Raz, N., Flash, T., & Karni, A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2035019100 · Cited by 378 · see citing works
Motor learning in man: a positron emission tomographic study
Seitz, R. J., Roland, P. E., Bohm, C., Greitz, T., & Stone-Elander, S. (1990) · NeuroReport · doi:10.1097/00001756-199009000-00016 · Cited by 376 · see citing works
Motor sequence learning with the nondominant left hand
Grafton, S. T., Hazeltine, E., & Ivry, R. B. (2002) · Experimental Brain Research · doi:10.1007/s00221-002-1181-y · Cited by 366 · see citing works
Involvement of the ipsilateral motor cortex in finger movements of different complexities
Chen, R. E., Gerloff, C. P., Hallett, M., & Cohen, L. G. (1997) · Annals of Neurology · doi:10.1002/ana.410410216 · Cited by 323 · see citing works
Peigneux, P., Laureys, S., Fuchs, S., Destrebecqz, A., Collette, F., Delbeuck, X., Phillips, C. L. M., Aerts, J. J., Fiore, G. D., Degueldre, C., et al. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00278-7 · Cited by 309 · see citing works
Sleep-dependent motor memory plasticity in the human brain
Walker, M. P., Stickgold, R., Alsop, D., Gaab, N., & Schlaug, G. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.007 · Cited by 308 · see citing works
Is the human primary motor cortex involved in motor imagery?
Dechent, P., Merboldt, K., & Frahm, J. (2004) · Cognitive Brain Research · doi:10.1016/j.cogbrainres.2003.11.012 · Cited by 266 · see citing works
Hund‐Georgiadis, M., & von Cramon, D. Y. (1999) · Experimental Brain Research · doi:10.1007/s002210050698 · Cited by 264 · see citing works
Integration of target and body-part information in the premotor cortex when planning action
Hoshi, E., & Tanji, J. (2000) · Nature · doi:10.1038/35044075 · Cited by 250 · see citing works
Dynamic Cortical and Subcortical Networks in Learning and Delayed Recall of Timed Motor Sequences
Penhune, V. B., & Doyon, J. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-04-01397.2002 · Cited by 244 · see citing works
Cellular and molecular connections between sleep and synaptic plasticity
Benington, J. H., & Frank, M. G. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00018-2 · Cited by 244 · see citing works
Maquet, P., Schwartz, S., Passingham, R. E., & Frith, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-04-01432.2003 · Cited by 199 · see citing works
Striatum forever, despite sequence learning variability: A random effect analysis of PET data
Peigneux, P., Maquet, P., Meulemans, T., Destrebecqz, A., Laureys, S., Degueldre, C., Delfiore, G., Aerts, J. J., Luxen, A., Franck, G., et al. (2000) · Human Brain Mapping · doi:10.1002/1097-0193(200008)10:4 · Cited by 172 · see citing works
Blinkenberg, M., Bonde, C., Holm, S., Svarer, C., Andersen, J., Paulson, O. B., & Law, I. G. (1996) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-199609000-00004 · Cited by 158 · see citing works
Conversion of Working Memory to Motor Sequence in the Monkey Premotor Cortex
Ohbayashi, M., Ohki, K., & Miyashita, Y. (2003) · Science · doi:10.1126/science.1084884 · Cited by 151 · see citing works
Asymmetry of cortical activation during maximum and convenient tapping speed
Lutz, K., Koeneke, S., Wüstenberg, T., & Jäncke, L. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.09.058 · Cited by 111 · see citing works
The effect of movement frequency on cerebral activation: a positron emission tomography study
Jenkins, I. H., Passingham, R. E., & Brooks, D. J. (1997) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(97)00145-7 · Cited by 90 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Diekelmann, S., & Born, J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2762 · Cited by 3,760 · see citing works
Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783 · see citing works
“Finally, sleep-dependent changes in brain activity indicative for a reorganization of memory representations have also been reported for procedural tasks like sequences finger tapping and visual texture discrimination (384, 1292, 1293).”
BackgroundNeuroplasticity Subserving Motor Skill Learning
Dayan, E., & Cohen, L. G. (2011) · Neuron · doi:10.1016/j.neuron.2011.10.008 · Cited by 1,408 · see citing works
Contributions of the basal ganglia and functionally related brain structures to motor learning
Doyon, J., Bellec, P., Amsel, R., Penhune, V., Monchi, O., Carrier, J., Lehéricy, S., & Benali, H. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.11.012 · Cited by 783 · see citing works
Astill, R. G., Van der Heijden, K. B., Van IJzendoorn, M. H., & Van Someren, E. J. W. (2012) · Psychological Bulletin · doi:10.1037/a0028204 · Cited by 707 · see citing works
The contribution of sleep to hippocampus-dependent memory consolidation
Marshall, L., & Born, J. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.09.001 · Cited by 667 · see citing works
The Restless Engram: Consolidations Never End
Dudai, Y. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150500 · Cited by 644 · see citing works
A quantitative meta-analysis and review of motor learning in the human brain
Hardwick, R. M., Rottschy, C., Miall, R. C., & Eickhoff, S. B. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.11.020 · Cited by 607 · see citing works
The whats and whens of sleep-dependent memory consolidation
Diekelmann, S., Wilhelm, I., & Born, J. (2009) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2008.08.002 · Cited by 566 · see citing works
Born, J., Rasch, B., & Gais, S. (2006) · The Neuroscientist · doi:10.1177/1073858406292647 · Cited by 557 · see citing works
Both the Hippocampus and Striatum Are Involved in Consolidation of Motor Sequence Memory
Albouy, G., Sterpenich, V., Balteau, E., Vandewalle, G., Desseilles, M., Dang-Vu, T., Darsaud, A., Ruby, P., Luppi, P.-H., Degueldre, C., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.02.008 · Cited by 463 · see citing works
Daytime sleep condenses the time course of motor memory consolidation
Korman, M., Doyon, J., Doljansky, J., Carrier, J., Dagan, Y., & Karni, A. (2007) · Nature Neuroscience · doi:10.1038/nn1959 · Cited by 408 · see citing works
The role of sleep in declarative memory consolidation: passive, permissive, active or none?
Ellenbogen, J. M., Payne, J. D., & Stickgold, R. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.10.006 · Cited by 326 · see citing works
Cued memory reactivation during sleep influences skill learning
Antony, J. W., Gobel, E. W., O'Hare, J. K., Reber, P. J., & Paller, K. A. (2012) · Nature Neuroscience · doi:10.1038/nn.3152 · Cited by 309 · see citing works
Brain plasticity related to the consolidation of motor sequence learning and motor adaptation
Debas, K., Carrier, J., Orban, P., Barakat, M., Lungu, O., Vandewalle, G., Tahar, A. H., Bellec, P., Karni, A., Ungerleider, L. G., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1013176107 · Cited by 295 · see citing works
Functional Neuroimaging Insights into the Physiology of Human Sleep.
Dang-Vu, T. T., Schabus, M., Desseilles, M., Sterpenich, V., Bonjean, M., & Maquet, P. (2010) · SLEEP · doi:10.1093/sleep/33.12.1589 · Cited by 284 · see citing works
Albouy, G., King, B. R., Maquet, P., & Doyon, J. (2013) · Hippocampus · doi:10.1002/hipo.22183 · Cited by 270 · see citing works
Sleep for Preserving and Transforming Episodic Memory
Inostroza, M., & Jan Born, A. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062012-170429 · Cited by 265 · see citing works
Genzel, L., Kroes, M. C. W., Dresler, M., & Battaglia, F. P. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.10.002 · Cited by 259 · see citing works
Functional neuroimaging insights into how sleep and sleep deprivation affect memory and cognition
Chee, M. W. L., & Chuah, L. Y. M. (2008) · Current Opinion in Neurology · doi:10.1097/wco.0b013e3283052cf7 · Cited by 261 · see citing works
Differential Effects of Non-REM and REM Sleep on Memory Consolidation?
Ackermann, S., & Rasch, B. (2014) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-013-0430-8 · Cited by 262 · see citing works
Doyon, J., Korman, M., Morin, A., Dostie, V., Tahar, A. H., Benali, H., Karni, A., Ungerleider, L. G., & Carrier, J. (2009) · Experimental Brain Research · doi:10.1007/s00221-009-1748-y · Cited by 247 · see citing works
Maintaining memories by reactivation
Rasch, B., & Born, J. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.11.007 · Cited by 240 · see citing works
From Creation to Consolidation: A Novel Framework for Memory Processing
Robertson, E. M. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000019 · Cited by 236 · see citing works
Sleep's function in the spontaneous recovery and consolidation of memories.
Drosopoulos, S., Schulze, C., Fischer, S., & Born, J. (2007) · Journal of Experimental Psychology: General · doi:10.1037/0096-3445.136.2.169 · Cited by 230 · see citing works
Self-citationManoach, D. S., Pan, J. Q., Purcell, S., & Stickgold, R. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.10.003 · Cited by 210 · see citing works
Motor Sequence Learning Increases Sleep Spindles and Fast Frequencies in Post-Training Sleep
(2008) · Sleep · doi:10.5665/sleep/31.8.1149 · Cited by 213 · see citing works
Sleeping on the motor engram: The multifaceted nature of sleep-related motor memory consolidation
King, B. R., Hoedlmoser, K., Hirschauer, F., Dolfen, N., & Albouy, G. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.04.026 · Cited by 202 · see citing works
Fast and slow spindle involvement in the consolidation of a new motor sequence
Barakat, M., Doyon, J., Debas, K., Vandewalle, G., Morin, A., Poirier, G., Martin, N., Lafortune, M., Karni, A., Ungerleider, L. G., et al. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.10.019 · Cited by 203 · see citing works
Motor sequence learning and movement disorders
Doyon, J. (2008) · Current Opinion in Neurology · doi:10.1097/wco.0b013e328304b6a3 · Cited by 194 · see citing works
Common mechanisms of human perceptual and motor learning
Censor, N., Sagi, D., & Cohen, L. G. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3315 · Cited by 190 · see citing works
Anticipated reward enhances offline learning during sleep.
Fischer, S., & Born, J. (2009) · Journal of Experimental Psychology: Learning, Memory, and Cognition · doi:10.1037/a0017256 · Cited by 186 · see citing works
Self-citationConsolidating the Effects of Waking and Sleep on Motor-Sequence Learning
Brawn, T. P., Fenn, K. M., Nusbaum, H. C., & Margoliash, D. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.3295-10.2010 · Cited by 181 · see citing works
Sleep and memory in mammals, birds and invertebrates
Vorster, A. P., & Born, J. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.09.020 · Cited by 169 · see citing works
Sleep does not enhance motor sequence learning.
Rickard, T. C., Cai, D. J., Rieth, C. A., Jones, J., & Ard, M. C. (2008) · Journal of Experimental Psychology: Learning, Memory, and Cognition · doi:10.1037/0278-7393.34.4.834 · Cited by 171 · see citing works
Strengthening Procedural Memories by Reactivation in Sleep
Schönauer, M., Geisler, T., & Gais, S. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00471 · Cited by 167 · see citing works
Albouy, G., Fogel, S. M., King, B. R., Laventure, S., Benali, H., Karni, A., Carrier, J., Robertson, E. M., & Doyon, J. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.12.049 · Cited by 167 · see citing works
Canto, C. B., Onuki, Y., Bruinsma, B., van der Werf, Y. D., & Zeeuw, C. I. D. (2017) · Trends in Neurosciences · doi:10.1016/j.tins.2017.03.001 · Cited by 168 · see citing works
Napping to renew learning capacity: enhanced encoding after stimulation of sleep slow oscillations
Antonenko, D., Diekelmann, S., Olsen, C., Jan Born, A., & Mölle, M. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12118 · Cited by 164 · see citing works
Neuronal networks in children with continuous spikes and waves during slow sleep
Siniatchkin, M., Groening, K., Moehring, J., Moeller, F., Boor, R., Brodbeck, V., Michel, C. M., Rodionov, R., Lemieux, L., & Stephani, U. (2010) · Brain · doi:10.1093/brain/awq183 · Cited by 160 · see citing works
Motor skill acquisition across short and long time scales: A meta-analysis of neuroimaging data
Lohse, K. R., Wadden, K. P., Boyd, L. A., & Hodges, N. J. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.05.001 · Cited by 157 · see citing works
The reorganisation of memory during sleep
Landmann, N., Kühn, M., Piosczyk, H., Feige, B., Baglioni, C., Spiegelhalder, K., Frase, L., Riemann, D. W., Sterr, A., & Nissen, C. (2014) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.03.005 · Cited by 153 · see citing works
Sleep and motor learning: Is there room for consolidation?
Pan, S. C., & Rickard, T. C. (2015) · Psychological Bulletin · doi:10.1037/bul0000009 · Cited by 154 · see citing works
Time- but Not Sleep-Dependent Consolidation of tDCS-Enhanced Visuomotor Skills
Reis, J., Fischer, J. T., Prichard, G., Weiller, C., Cohen, L. G., & Fritsch, B. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht208 · Cited by 150 · see citing works
Enhanced emotional reactivity after selective REM sleep deprivation in humans: an fMRI study
Rosales-Lagarde, A., Armony, J. L., del Río‐Portilla, Y., Trejo‐Martínez, D., Conde, R., & Corsi‐Cabrera, M. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00025 · Cited by 143 · see citing works
Fischer, S., Wilhelm, I., & Born, J. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2007.19.2.214 · Cited by 142 · see citing works
Self-citationAcute Exercise and Motor Memory Consolidation: The Role of Exercise Intensity
Thomas, R., Johnsen, L. K., Geertsen, S. S., Christiansen, L., Ritz, C., Roig, M., & Lundbye‐Jensen, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159589 · Cited by 137 · see citing works
Albouy, G., Fogel, S. M., Pottiez, H., Nguyen, V. A., Ray, L. B., Lungu, O., Carrier, J., Robertson, E. M., & Doyon, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0052805 · Cited by 137 · see citing works
Albouy, G., Virginie Sterpenich, A., Vandewalle, G., Darsaud, A., Gais, S., Rauchs, G., Desseilles, M., Boly, M., Dang‐Vu, T. T., Balteau, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059490 · Cited by 130 · see citing works
A functional magnetic resonance imaging study
Yong, Huang, Huiling, Xiao, X., Junqi, Chen, Shanshan, Qü, YU, Y.-Y., Zheng, Z., et al. (2011) · 中国神经再生研究：英文版 · Cited by 132 · see citing works
Gulati, T., Ramanathan, D., Wong, C. C., & Ganguly, K. (2014) · Nature Neuroscience · doi:10.1038/nn.3759 · Cited by 122 · see citing works
Reduced sleep spindle activity point to a TRN-MD thalamus-PFC circuit dysfunction in schizophrenia
Ferrarelli, F., & Tononi, G. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.05.023 · Cited by 109 · see citing works
Genzel, L., Dresler, M., Cornu, M., Jäger, E., Konrad, B. N., Adamczyk, M., Frieß, E., Steiger, A., Czisch, M., & Goya‐Maldonado, R. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.06.004 · Cited by 111 · see citing works
Sleep spindles predict neural and behavioral changes in motor sequence consolidation
Barakat, M., Carrier, J., Debas, K., Lungu, O., Fogel, S. M., Vandewalle, G., Hoge, R. D., Bellec, P., Karni, A., Ungerleider, L. G., et al. (2012) · Human Brain Mapping · doi:10.1002/hbm.22116 · Cited by 110 · see citing works
Sleep function: current questions and new approaches
Vassalli, A., & Dijk, D. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06767.x · Cited by 110 · see citing works
Predicting the future: From implicit learning to consolidation
Janacsek, K., & Németh, D. (2011) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2011.11.012 · Cited by 110 · see citing works
Memory consolidation during sleep: Interactive effects of sleep stages and HPA regulation: Review
Wagner, U., & Born, J. (2008) · Stress · doi:10.1080/10253890701408822 · Cited by 107 · see citing works
Fogel, S. M., Albouy, G., King, B. R., Lungu, O., Vien, C., Boré, A., Pinsard, B., Benali, H., Carrier, J., & Doyon, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174755 · Cited by 107 · see citing works
Newbury, C. R., Crowley, R., Rastle, K., & Tamminen, J. (2021) · Psychological Bulletin · doi:10.1037/bul0000348 · Cited by 113 · see citing works
Neural representations during sleep: From sensory processing to memory traces
Hennevin, E., Huetz, C., & Edeline, J.-M. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2006.10.006 · Cited by 133 · see citing works
The role of sleep in motor sequence consolidation: stabilization rather than enhancement
Nettersheim, A., Hallschmid, M., Born, J., & Diekelmann, S. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.1236-14.2015 · Cited by 104 · see citing works
Papitto, G., Friederici, A. D., & Zaccarella, E. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.116321 · Cited by 98 · see citing works
Sleep Loss Produces False Memories
Diekelmann, S., Landolt, H.-P., Lahl, O., Born, J., & Wagner, U. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003512 · Cited by 103 · see citing works
Memory consolidation in sleep disorders
Cellini, N. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.09.003 · Cited by 105 · see citing works
Better than sleep: Theta neurofeedback training accelerates memory consolidation
Reiner, M., Rozengurt, R., & Barnea, A. (2013) · Biological Psychology · doi:10.1016/j.biopsycho.2013.10.010 · Cited by 94 · see citing works
Mechanisms of offline motor learning at a microscale of seconds in large-scale crowdsourced data
Bönstrup, M., Iturrate, I., Hebart, M. N., Censor, N., & Cohen, L. G. (2020) · npj Science of Learning · doi:10.1038/s41539-020-0066-9 · Cited by 94 · see citing works
Cousins, J. N., El‐Deredy, W., Parkes, L. M., Hennies, N., & Lewis, P. A. (2016) · PLoS Biology · doi:10.1371/journal.pbio.1002451 · Cited by 91 · see citing works
Does abnormal sleep impair memory consolidation in schizophrenia?
Manoach, D. S. (2009) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.021.2009 · Cited by 91 · see citing works
Acute Exercise and Motor Memory Consolidation: The Role of Exercise Timing
Thomas, R. V. R., Beck, M. M., Lind, R. R., Johnsen, L. K., Geertsen, S. S., Christiansen, L., Ritz, C., Roig, M., & Lundbye‐Jensen, J. (2016) · Neural Plasticity · doi:10.1155/2016/6205452 · Cited by 84 · see citing works
Debas, K., Carrier, J., Barakat, M., Marrelec, G., Bellec, P., Tahar, A. H., Karni, A., Ungerleider, L. G., Benali, H., & Doyon, J. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.05.022 · Cited by 83 · see citing works
Network-wide reorganization of procedural memory during NREM sleep revealed by fMRI
Vahdat, S., Fogel, S. M., Benali, H., & Doyon, J. (2017) · eLife · doi:10.7554/elife.24987 · Cited by 83 · see citing works
Tamaki, M., Huang, T.-R., Yotsumoto, Y., Hämäläinen, M., Lin, F., Náñez, J. E., Watanabe, T., & Sasaki, Y. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.1198-13.2013 · Cited by 81 · see citing works
Sleep Enhances Implicit Motor Skill Learning in Individuals Poststroke
Siengsukon, C. F., & Boyd, L. A. (2008) · Topics in Stroke Rehabilitation · doi:10.1310/tsr1501-1 · Cited by 82 · see citing works
A Meta-analysis of Voxel-based Brain Morphometry Studies in Obstructive Sleep Apnea
Shi, Y., Chen, L., Chen, T., Li, L., Dai, J., Lui, S., Huang, X., Sweeney, J. A., & Gong, Q. (2017) · Scientific Reports · doi:10.1038/s41598-017-09319-6 · Cited by 81 · see citing works
Understanding Consolidation through the Architecture of Memories
Robertson, E. M., & Cohen, D. A. (2006) · The Neuroscientist · doi:10.1177/1073858406287935 · Cited by 81 · see citing works
Nocturnal Mnemonics: Sleep and Hippocampal Memory Processing
Saletin, J., & Walker, M. P. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00059 · Cited by 76 · see citing works
Neural correlates of performance variability during motor sequence acquisition
Albouy, G., Virginie Sterpenich, A., Vandewalle, G., Darsaud, A., Gais, S., Rauchs, G., Desseilles, M., Boly, M., Dang‐Vu, T. T., Balteau, E., et al. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.12.049 · Cited by 73 · see citing works
Large-scale structure and individual fingerprints of locally coupled sleep oscillations
Cox, R., Mylonas, D., Manoach, D. S., & Stickgold, R. (2018) · SLEEP · doi:10.1093/sleep/zsy175 · Cited by 67 · see citing works
Sleep Contribution to Motor Memory Consolidation: A Motor Imagery Study
Debarnot, U., Creveaux, T., Collet, C., Doyon, J., & Guillot, A. (2009) · SLEEP · doi:10.1093/sleep/32.12.1559 · Cited by 65 · see citing works
Sleeping Unsafely Tucked in to Conserve Energy in a Nocturnal Migratory Songbird
Ferretti, A., Rattenborg, N. C., Ruf, T., McWilliams, S. R., Cardinale, M., & Fusani, L. (2019) · Current Biology · doi:10.1016/j.cub.2019.07.028 · Cited by 64 · see citing works
Tanaka, S., Sandrini, M., & Cohen, L. (2011) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2011.605589 · Cited by 64 · see citing works
Daytime naps improve motor imagery learning
Debarnot, U., Castellani, E., Valenza, G., Sebastiani, L., & Guillot, A. (2011) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-011-0052-z · Cited by 62 · see citing works
King, B. R., Saucier, P., Albouy, G., Fogel, S. M., Rumpf, J., Klann, J., Buccino, G., Binkofski, F., Claßen, J., Karni, A., et al. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhv347 · Cited by 65 · see citing works
Furman, O., Mendelsohn, A., & Dudai, Y. (2012) · Learning & Memory · doi:10.1101/lm.025965.112 · Cited by 65 · see citing works
Prehn-Kristensen, A., Molzow, I., Munz, M., Wilhelm, I., Müller, K., Freytag, D., Wiesner, C. D., & Baving, L. (2011) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2011.06.021 · Cited by 62 · see citing works
Hotermans, C., Peigneux, P., de Noordhout, A. M., Moonen, G., & Maquet, P. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06421.x · Cited by 61 · see citing works
Rasch, B., Gais, S., & Born, J. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.6 · Cited by 57 · see citing works
Tanaka, S., Honda, M., Hanakawa, T., & Cohen, L. G. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp276 · Cited by 56 · see citing works
Mander, B. A., Zhu, A. H., Lindquist, J. R., Villeneuve, S., Rao, V. R., Lu, B. S., Saletin, J., Ancoli‐Israel, S., Jagust, W. J., & Walker, M. P. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3033-16.2017 · Cited by 56 · see citing works
One memory, two ways to consolidate?
Diekelmann, S., & Born, J. (2007) · Nature Neuroscience · doi:10.1038/nn0907-1085 · Cited by 51 · see citing works
The malleable brain: plasticity of neural circuits and behavior – a review from students to students
Schaefer, N., Rotermund, C., Blumrich, E., Lourenco, M. V., Joshi, P., Hegemann, R. U., Jamwal, S., Ali, N., Romero, E. M. G., Sharma, S., et al. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14107 · Cited by 50 · see citing works
Tzvi, E., Stoldt, A., Witt, K., & Krämer, U. M. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.07.077 · Cited by 49 · see citing works
Pocivavsek, A., & Rowland, L. M. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx151 · Cited by 47 · see citing works
Reconsidering the role of sleep for motor memory.
Cai, D. J., & Rickard, T. C. (2009) · Behavioral Neuroscience · doi:10.1037/a0017672 · Cited by 46 · see citing works
Theta EEG neurofeedback benefits early consolidation of motor sequence learning
Rozengurt, R., Barnea, A., Uchida, S., & Levy, D. A. (2016) · Psychophysiology · doi:10.1111/psyp.12656 · Cited by 46 · see citing works
Does Sleep Promote Motor Learning? Implications for Physical Rehabilitation
Siengsukon, C. F., & Boyd, L. A. (2009) · Physical Therapy · doi:10.2522/ptj.20080310 · Cited by 45 · see citing works
Sleep Consolidation of Interfering Auditory Memories in Starlings
Brawn, T. P., Nusbaum, H. C., & Margoliash, D. (2013) · Psychological Science · doi:10.1177/0956797612457391 · Cited by 44 · see citing works
Spoormaker, V. I., Czisch, M., Maquet, P., & Jäncke, L. (2011) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.2011.0078 · Cited by 46 · see citing works
Statistical learning occurs during practice while high-order rule learning during rest period
Quentin, R., Fanuel, L., Kiss, M. M., Vernet, M., Vékony, T., Janacsek, K., Cohen, L. G., & Németh, D. (2021) · npj Science of Learning · doi:10.1038/s41539-021-00093-9 · Cited by 44 · see citing works
Motor Sequence Learning and Developmental Dyslexia
Orban, P., Lungu, O., & Doyon, J. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1416.016 · Cited by 39 · see citing works
- Authors
- Fischer, S., Nitschke, M. F., Melchert, U. H., Erdmann, C., & Born, J.
- Affiliations
- University of Lübeck (DE)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2005-12-07
- Volume
- 25
- Issue
- 49
- Pages
- 11248-11255
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6725908
- OpenAlex
- W2072731687
- Cited by
- 255
- References
- 49
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 1 · 2023: 10 · 2022: 6 · 2021: 12 · 2020: 9 · 2019: 5 · 2018: 8 · 2017: 16 · 2016: 18 · 2015: 8 · 2014: 24 · 2013: 23 · 2012: 18
- FWCI
- 7.12
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Volkswagen Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Keywords
- motor memory consolidation, sleep-dependent learning, motor skill learning, sleep deprivation, prefrontal cortex, premotor cortex, primary motor cortex, parietal cortex
- MeSH terms
- Adolescent, Adult, Brain, Brain Mapping, Female, Humans, Magnetic Resonance Imaging, Male, Memory, Psychomotor Performance, Sleep, Polysomnography
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