Sleep function: current questions and new approaches

Vassalli, Anne; Dijk, Derk‐Jan

doi:10.1111/j.1460-9568.2009.06767.x

Cited by 110Sleep and Wakefulness ResearchNeural dynamics and brain functionNeuroscience of respiration and sleep

Sleep function: current questions and new approaches

Open access

Vassalli, Anne, Dijk, Derk‐Jan·2009·European Journal of Neuroscience

DOI 10.1111/j.1460-9568.2009.06767.x

Open this paper in CoChat — free account Open PDF

Abstract

The mammalian brain oscillates through three distinct global activity states: wakefulness, non‐rapid eye movement (NREM) sleep and REM sleep. The regulation and function of these ‘vigilance’ or ‘behavioural’ states can be investigated over a broad range of temporal and spatial scales and at different levels of functional organization, i.e. from gene expression to memory, in single neurons, cortical columns or the whole brain and organism. We summarize some basic questions that have arisen from recent approaches in the quest for the functions of sleep. Whereas traditionally sleep was viewed to be regulated through top‐down control mechanisms, recent approaches have emphasized that sleep is emerging locally and regulated in a use‐dependent (homeostatic) manner. Traditional markers of sleep homeostasis, such as the electroencephalogram slow‐wave activity, have been linked to changes in connectivity and plasticity in local neuronal networks. Thus waking experience‐induced local network changes may be sensed by the sleep homeostatic process and used to mediate sleep‐dependent events, benefiting network stabilization and memory consolidation. Although many questions remain unanswered, the available data suggest that sleep function will best be understood by an analysis which integrates sleep’s many functional levels with its local homeostatic regulation.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1111/j.1460-9568.2009.06767.x

Cites

114 of 114 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The finding challenges the belief that sleep primarily restores central nervous system function and suggests that sleep may play an equally important role in peripheral energy metabolism.
“Further, our finding of marked alterations in adipocyte function after experimental sleep restriction challenges the widely held belief that the primary function of sleep is the restoration of central nervous system function (26–29) and suggests that sleep may play an equally important role in peripheral energy metabolism.”
From Impaired Insulin Signaling in Human Adipocytes After Experimental Sleep Restriction: A Randomized, Crossover Study (2012) · cites this paper as [28]
The Background (p. 1) presents restoration of brain function as a traditional view of sleep, and the discussion of sleep homeostasis (p. 5) cites evidence that sleep reverses changes in the brain caused by wakefulness. But the paper treats whether sleep has one primary function as an open question (p. 5); it does not endorse CNS restoration as the primary function. The adipocyte finding and inference about peripheral metabolism are the citing authors’ own, not claims attributed to this source. (LLM, conf=0.82)
Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Two-Process Model of Sleep Regulation
Binder, M. D., Hirokawa, N., & Windhorst, U. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_6166 · Cited by 3,895 · see citing works
Thalamocortical oscillations in the sleeping and aroused brain
Steriade, M., McCormick, D. A., & Sejnowski, T. J. (1993) · Science · doi:10.1126/science.8235588 · Cited by 3,564 · see citing works
Reactivation of hippocampal ensemble memories during sleep
Wilson, M. A., & McNaughton, B. L. (1994) · Science · doi:10.1126/science.8036517 · Cited by 3,118 · see citing works
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804 · see citing works
Homeostatic plasticity in the developing nervous system
Turrigiano, G. G., & Nelson, S. B. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1327 · Cited by 2,485 · see citing works
Sleep function and synaptic homeostasis
Tononi, G., & Cirelli, C. (2006) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2005.05.002 · Cited by 2,151 · see citing works
Local sleep and learning
Huber, R., Felice Ghilardi, M., Massimini, M., & Tononi, G. (2004) · Nature · doi:10.1038/nature02663 · Cited by 1,854 · see citing works
Boosting slow oscillations during sleep potentiates memory
Marshall, L., Helgadóttir, H., Mölle, M., & Born, J. (2006) · Nature · doi:10.1038/nature05278 · Cited by 1,792 · see citing works
The Neurobiology of Consolidations, Or, How Stable is the Engram?
Dudai, Y. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.55.090902.142050 · Cited by 1,671 · see citing works
Coordinated memory replay in the visual cortex and hippocampus during sleep
Ji, D., & Wilson, M. A. (2007) · Nature Neuroscience · doi:10.1038/nn1825 · Cited by 1,669 · see citing works
The genetics of mammalian circadian order and disorder: implications for physiology and disease
Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2430 · Cited by 1,611 · see citing works
Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: a sleep dose-response study
Belenky, G., Wesensten, N. J., Thorne, D. R., Thomas, M. L., Sing, H. C., Redmond, D. P., Russo, M. B., & Balkin, T. J. (2003) · Journal of Sleep Research · doi:10.1046/j.1365-2869.2003.00337.x · Cited by 1,436 · see citing works
Timing of human sleep: recovery process gated by a circadian pacemaker
Daan, S., Beersma, D. G. M., & Borbély, A. A. (1984) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1984.246.2.r161 · Cited by 1,424 · see citing works
Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans
Dijk, D., & Czeisler, C. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03526.1995 · Cited by 1,356 · see citing works
Self-citation
Correlates of Sleep and Waking in Drosophila melanogaster
Shaw, P. J., Cirelli, C., Greenspan, R. J., & Tononi, G. (2000) · Science · doi:10.1126/science.287.5459.1834 · Cited by 1,300 · see citing works
The sleep slow oscillation as a traveling wave
Massimini, M., Huber, R., Ferrarelli, F., Hill, S., & Tononi, G. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1318-04.2004 · Cited by 1,221 · see citing works
Sleep and synaptic homeostasis: a hypothesis
Tononi, G., & Cirelli, C. (2003) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2003.09.004 · Cited by 1,217 · see citing works
Odor cues during slow-wave sleep prompt declarative memory consolidation
Rasch, B., Büchel, C., Gais, S., & Born, J. (2007) · Science · doi:10.1126/science.1138581 · Cited by 1,181 · see citing works
Clues to the functions of mammalian sleep
Siegel, J. M. (2005) · Nature · doi:10.1038/nature04285 · Cited by 1,040 · see citing works
Slow-wave sleep and the risk of type 2 diabetes in humans
Tasali, E., Leproult, R., Ehrmann, D. A., & Van Cauter, E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706446105 · Cited by 921 · see citing works
Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep
Vyazovskiy, V. V., Cirelli, C., Pfister-Genskow, M., Faraguna, U., & Tononi, G. (2008) · Nature Neuroscience · doi:10.1038/nn2035 · Cited by 837 · see citing works
Are spatial memories strengthened in the human hippocampus during slow wave sleep?
Peigneux, P., Laureys, S., Fuchs, S., Collette, F., Perrin, F., Reggers, J., Phillips, C., Degueldre, C., Del Fiore, G., Aerts, J., et al. (2004) · Neuron · doi:10.1016/j.neuron.2004.10.007 · Cited by 766 · see citing works
Experience-dependent changes in cerebral activation during human REM sleep
Maquet, P., Laureys, S., Peigneux, P., Fuchs, S., Petiau, C., Phillips, C., Aerts, J., Del Fiore, G., Degueldre, C., Meulemans, T., et al. (2000) · Nature Neuroscience · doi:10.1038/77744 · Cited by 747 · see citing works
Effect of SCN lesions on sleep in squirrel monkeys: evidence for opponent processes in sleep-wake regulation
Edgar, D. M., Dement, W., & Fuller, C. A. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-03-01065.1993 · Cited by 685 · see citing works
Sites of Neocortical Reorganization Critical for Remote Spatial Memory
Maviel, T., Durkin, T., Menzaghi, F., & Bontempi, B. (2004) · Science · doi:10.1126/science.1098180 · Cited by 659 · see citing works
Extensive and divergent effects of sleep and wakefulness on brain gene expression
Cirelli, C., Gutierrez, C. M., & Tononi, G. (2004) · Neuron · doi:10.1016/s0896-6273(03)00814-6 · Cited by 627 · see citing works
Emotional memory formation is enhanced across sleep intervals with high amounts of rapid eye movement sleep
Wagner, U., Gais, S., & Born, J. (2001) · Learning & Memory · doi:10.1101/lm.36801 · Cited by 605 · cited 1× · see citing works
“Amygdala-dependent emotional memories were also shown to benefit specifically from late REM sleep-rich sleep (Wagner et al., 2001).”
Background
Circadian and sleep/wake dependent aspects of subjective alertness and cognitive performance
Dijk, D., Duffy, J. F., & Czeisler, C. A. (1992) · Journal of Sleep Research · doi:10.1111/j.1365-2869.1992.tb00021.x · Cited by 602 · see citing works
Self-citation
Sleep as a fundamental property of neuronal assemblies
Krueger, J. M., Rector, D. M., Roy, S., Van Dongen, H. P. A., Belenky, G., & Panksepp, J. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2521 · Cited by 596 · see citing works
Fast-Forward Playback of Recent Memory Sequences in Prefrontal Cortex During Sleep
Euston, D. R., Tatsuno, M., & McNaughton, B. L. (2007) · Science · doi:10.1126/science.1148979 · Cited by 586 · see citing works
Sleep Spindles and Their Significance for Declarative Memory Consolidation
Schabus, M., Gruber, G., Parapatics, S., Sauter, C., Klösch, G., Anderer, P., Klimesch, W., Saletu, B., & Zeitlhofer, J. (2004) · Sleep · doi:10.1093/sleep/27.7.1479 · Cited by 560 · see citing works
Sleep to Remember
Born, J., Rasch, B., & Gais, S. (2006) · The Neuroscientist · doi:10.1177/1073858406292647 · Cited by 557 · see citing works
The Homeostatic Regulation of Sleep Need Is under Genetic Control
Franken, P., Chollet, D., & Tafti, M. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02610.2001 · Cited by 551 · see citing works
Transcranial direct current stimulation during sleep improves declarative memory
Marshall, L., Mölle, M., Hallschmid, M., & Born, J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2725-04.2004 · Cited by 548 · see citing works
Neurobiology of REM and NREM sleep
McCarley, R. W. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2007.03.005 · Cited by 538 · see citing works
Daytime naps, motor memory consolidation and regionally specific sleep spindles
Nishida, M., & Walker, M. P. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000341 · Cited by 531 · see citing works
Lack of the Burst Firing of Thalamocortical Relay Neurons and Resistance to Absence Seizures in Mice Lacking α1G T-Type Ca2+ Channels
Kim, D., Song, I., Keum, S., Lee, T., Jeong, M.-J., Kim, S.-S., McEnery, M. W., & Shin, H. (2001) · Neuron · doi:10.1016/s0896-6273(01)00343-9 · Cited by 523 · see citing works
PER3 polymorphism predicts sleep structure and waking performance
Viola, A. U., Archer, S. N., James, L. M., Groeger, J. A., Lo, J. C. Y., Skene, D. J., von Schantz, M., & Dijk, D.-J. (2007) · Current Biology · doi:10.1016/j.cub.2007.01.073 · Cited by 520 · see citing works
Self-citation
The effects of age and gender on sleep EEG power spectral density in the middle years of life (ages 20–60 years old)
Carrier, J., Land, S., Buysse, D. J., Kupfer, D. J., & Monk, T. H. (2001) · Psychophysiology · doi:10.1111/1469-8986.3820232 · Cited by 494 · see citing works
Circadian temperature and melatonin rhythms, sleep, and neurobehavioral function in humans living on a 20-h day
Wyatt, J. K., Cecco, A. R.-D., Czeisler, C. A., & Dijk, D. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.277.4.r1152 · Cited by 473 · see citing works
Self-citation
Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study
Porkka‐Heiskanen, T., Strecker, R. E., & McCarley, R. W. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00220-7 · Cited by 463 · see citing works
Sleep Homeostasis and Cortical Synchronization: III. A High-Density EEG Study of Sleep Slow Waves in Humans
Riedner, B. A., Vyazovskiy, V. V., Huber, R., Massimini, M., Esser, S., Murphy, M., & Tononi, G. (2007) · Sleep · doi:10.1093/sleep/30.12.1643 · Cited by 424 · cited 1× · see citing works
“These parameters have now been shown in rat and humans to increase with wake and decrease with sleep (Riedner et al., 2007; Vyazovskiy et al., 2007, 2008).”
Background
Modeling Sleep and Wakefulness in the Thalamocortical System
Hill, S., & Tononi, G. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00915.2004 · Cited by 417 · see citing works
Pattern-Specific Associative Long-Term Potentiation Induced by a Sleep Spindle-Related Spike Train
Rosanova, M., & Ulrich, D. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2149-05.2005 · Cited by 413 · see citing works
Sleep transforms the cerebral trace of declarative memories
Gais, S., Albouy, G., Boly, M., Dang-Vu, T. T., Darsaud, A., Desseilles, M., Rauchs, G., Schabus, M., Sterpenich, V., Vandewalle, G., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705454104 · Cited by 412 · see citing works
Effect of unilateral somatosensory stimulation prior to sleep on the sleep EEG in humans
KATTLER, H., DIJK, D., & BORBÉLY, A. A. (1994) · Journal of Sleep Research · doi:10.1111/j.1365-2869.1994.tb00123.x · Cited by 401 · see citing works
Self-citation
Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature
Franken, P., Dijk, D., Tobler, I., & Borbély, A. A. (1991) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1991.261.1.r198 · Cited by 400 · see citing works
Self-citation
EEG Power Density during Nap Sleep: Reflection of an Hourglass Measuring the Duration of Prior Wakefulness
Dijk, D., Beersma, D. G. M., & Daan, S. (1987) · Journal of Biological Rhythms · doi:10.1177/074873048700200304 · Cited by 369 · see citing works
Self-citation
Homer1a is a core brain molecular correlate of sleep loss
Maret, S., Dorsaz, S., Gurcel, L., Pradervand, S., Petit, B., Pfister, C., Hagenbüchle, O., O’Hara, B. F., Franken, P., & Tafti, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710131104 · Cited by 366 · see citing works
Are corticothalamic ‘up’ states fragments of wakefulness?
Destexhe, A., Hughes, S. W., Rudolph, M., & Crunelli, V. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.04.006 · Cited by 355 · see citing works
Effect of age on the sleep EEG: slow-wave activity and spindle frequency activity in young and middle-aged men
Landolt, H.-P., Dijk, D.-J., Achermann, P., & Borbély, A. A. (1996) · Brain Research · doi:10.1016/s0006-8993(96)00770-6 · Cited by 350 · see citing works
Self-citation
Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves
Esser, S. K., Hill, S. L., & Tononi, G. (2007) · Sleep · doi:10.1093/sleep/30.12.1617 · Cited by 315 · see citing works
A neuronal group theory of sleep function
Krueger, J. M., & Obál, F. (1993) · Journal of Sleep Research · doi:10.1111/j.1365-2869.1993.tb00064.x · Cited by 314 · see citing works
Cetacean sleep: An unusual form of mammalian sleep
Lyamin, O. I., Manger, P. R., Ridgway, S. H., Mukhametov, L. M., & Siegel, J. M. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.05.023 · Cited by 313 · see citing works
Learned material content and acquisition level modulate cerebral reactivation during posttraining rapid-eye-movements sleep
Peigneux, P., Laureys, S., Fuchs, S., Destrebecqz, A., Collette, F., Delbeuck, X., Phillips, C. L. M., Aerts, J. J., Fiore, G. D., Degueldre, C., et al. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00278-7 · Cited by 309 · see citing works
Sleep-dependent motor memory plasticity in the human brain
Walker, M. P., Stickgold, R., Alsop, D., Gaab, N., & Schlaug, G. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.007 · Cited by 308 · see citing works
Insomnia causes, consequences, and therapeutics: An overview
Drake, C. L., Roehrs, T., & Roth, T. G. (2003) · Depression and Anxiety · doi:10.1002/da.10151 · Cited by 307 · see citing works
Interhemispheric asymmetry of the electroencephalographic sleep patterns in dolphins
Mukhametov, L. M., Supin, A., & Polyakova, I. G. (1977) · Brain Research · doi:10.1016/0006-8993(77)90835-6 · Cited by 301 · see citing works
Sleep: A Marker of Physical and Mental Health in the Elderly
Reid, K. J., Martinovich, Z., Finkel, S. I., Statsinger, J., Golden, R., Harter, K., & Zee, P. C. (2006) · American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000206164.56404.ba · Cited by 287 · see citing works
Unearthing the phylogenetic roots of sleep
Allada, R., & Siegel, J. M. (2008) · Current Biology · doi:10.1016/j.cub.2008.06.033 · Cited by 280 · see citing works
Extraction of sleep-promoting factor S from cerebrospinal fluid and from brains of sleep-deprived animals
Pappenheimer, J. R., Koski, G., Fencl, V., Karnovsky, M. L., & Krueger, J. M. (1975) · Journal of Neurophysiology · doi:10.1152/jn.1975.38.6.1299 · Cited by 270 · see citing works
The electroencephalographic fingerprint of sleep is genetically determined: A twin study
Gennaro, L. D., Marzano, C., Fratello, F., Moroni, F., Pellicciari, M. C., Ferlazzo, F., Costa, S., Couyoumdjian, A., Curcio, G., Sforza, E. A., et al. (2008) · Annals of Neurology · doi:10.1002/ana.21434 · Cited by 268 · see citing works
A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans
Rétey, J., Adam, M., Honegger, E., Khatami, R., Luhmann, U. F. O., Jung, H. H., Berger, W., & Landolt, H. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505414102 · Cited by 260 · see citing works
Pharmacological REM sleep suppression paradoxically improves rather than impairs skill memory
Rasch, B., Pommer, J., Diekelmann, S., & Born, J. (2009) · Nature Neuroscience · doi:10.1038/nn.2206 · Cited by 259 · see citing works
Motor Memory Consolidation in Sleep Shapes More Effective Neuronal Representations
Fischer, S., Nitschke, M. F., Melchert, U. H., Erdmann, C., & Born, J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1743-05.2005 · Cited by 255 · see citing works
Variation of electroencephalographic activity during non‐rapid eye movement and rapid eye movement sleep with phase of circadian melatonin rhythm in humans
Dijk, D., Shanahan, T. L., Duffy, J. F., Ronda, J. M., & Czeisler, C. A. (1997) · The Journal of Physiology · doi:10.1111/j.1469-7793.1997.851ba.x · Cited by 250 · see citing works
Self-citation
Contribution of night and day sleep vs. simple passage of time to the consolidation of motor sequence and visuomotor adaptation learning
Doyon, J., Korman, M., Morin, A., Dostie, V., Tahar, A. H., Benali, H., Karni, A., Ungerleider, L. G., & Carrier, J. (2009) · Experimental Brain Research · doi:10.1007/s00221-009-1748-y · Cited by 247 · see citing works
Mechanisms of sleep-dependent consolidation of cortical plasticity
Aton, S. J., Seibt, J., Dumoulin, M., Jha, S. K., Steinmetz, N., Coleman, T., Naidoo, N., & Frank, M. G. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.007 · Cited by 244 · see citing works
Timing and Consolidation of Human Sleep, Wakefulness, and Performance by a Symphony of Oscillators
Dijk, D., & von Schantz, M. (2005) · Journal of Biological Rhythms · doi:10.1177/0748730405278292 · Cited by 243 · see citing works
Self-citation
Time course of EEG power density during long sleep in humans
Dijk, D., Brunner, D. P., & Borbély, A. A. (1990) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1990.258.3.r650 · Cited by 239 · see citing works
Self-citation
Strength through Diversity
Nelson, S. B., & Turrigiano, G. G. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.020 · Cited by 233 · see citing works
Encoding Difficulty Promotes Postlearning Changes in Sleep Spindle Activity during Napping
Schmidt, C., Peigneux, P., Muto, V., Schenkel, M., Knoblauch, V., Münch, M. Y., de Quervain, D. J. ‐., Wirz‐Justice, A., & Cajochen, C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2464-06.2006 · Cited by 230 · see citing works
Sleep homeostasis and cortical synchronization: II. A local field potential study of sleep slow waves in the rat
Vyazovskiy, V. V., Riedner, B. A., Cirelli, C., & Tononi, G. (2007) · SLEEP · doi:10.1093/sleep/30.12.1631 · Cited by 225 · see citing works
Exploratory Behavior, Cortical BDNF Expression, and Sleep Homeostasis
Huber, R., Tononi, G., & Cirelli, C. (2007) · Sleep · doi:10.1093/sleep/30.2.129 · Cited by 224 · see citing works
Neuronal correlates of sleep, wakefulness and arousal in a diurnal insect
Kaiser, W., & Steiner-Kaiser, J. (1983) · Nature · doi:10.1038/301707a0 · Cited by 222 · see citing works
T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites
Cueni, L., Canepari, M., Luján, R., Emmenegger, Y., Watanabe, M., Bond, C. T., Franken, P., Adelman, J. P., & Lüthi, A. (2008) · Nature Neuroscience · doi:10.1038/nn.2124 · Cited by 215 · see citing works
Paradoxical (REM) sleep genesis: The switch from an aminergic–cholinergic to a GABAergic–glutamatergic hypothesis
Luppi, P., Gervasoni, D., Verret, L., Goutagny, R., Peyron, C., Salvert, D., Léger, L., & Fort, P. (2006) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2007.05.006 · Cited by 214 · see citing works
Trait interindividual differences in the sleep physiology of healthy young adults
Tucker, A. M., Dinges, D. F., & Dongen, H. P. A. V. (2007) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2007.00594.x · Cited by 206 · see citing works
Sex Differences in the Sleep EEG of Young Adults: Visual Scoring and Spectral Analysis
Dijk, D., Beersma, D. G. M., & Bloem, G. M. (1989) · SLEEP · doi:10.1093/sleep/12.6.500 · Cited by 206 · see citing works
Self-citation
<b>Fast track:</b>Unilateral vibrissae stimulation during waking induces interhemispheric EEG asymmetry during subsequent sleep in the rat
Vyazovskiy, V., Borbély, A. A., & Tobler, I. (2000) · Journal of Sleep Research · doi:10.1046/j.1365-2869.2000.00230.x · Cited by 203 · see citing works
Thalamic Ca v 3.1 T-type Ca 2 + channel plays a crucial role in stabilizing sleep
Anderson, M. P., Mochizuki, T., Xie, J., Fischler, W., Manger, J. P., Talley, E. M., Scammell, T. E., & Tonegawa, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409644102 · Cited by 201 · see citing works
Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking α1 G -subunit of T-type calcium channels
Lee, J., Kim, D., & Shin, H. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408089101 · Cited by 197 · see citing works
Age-Related Reduction in the Maximal Capacity for Sleep—Implications for Insomnia
Klerman, E. B., & Dijk, D. (2008) · Current Biology · doi:10.1016/j.cub.2008.06.047 · Cited by 193 · see citing works
Self-citation
Separation of circadian and wake duration-dependent modulation of EEG activation during wakefulness
Cajochen, C., Wyatt, J. K., Czeisler, C. A., & Dijk, D. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00209-9 · Cited by 192 · see citing works
Self-citation
Status dissociatus--a perspective on states of being
Mahowald, M. W., & Schenck, C. H. (1991) · Sleep · doi:10.1093/sleep/14.1.69 · Cited by 182 · see citing works
When Clocks Go Bad: Neurobehavioural Consequences of Disrupted Circadian Timing
Barnard, A. R., & Nolan, P. M. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000040 · Cited by 181 · see citing works
Sleep and sensorimotor integration during early vocal learning in a songbird
Shank, S. S., & Margoliash, D. (2009) · Nature · doi:10.1038/nature07615 · Cited by 178 · cited 2× · see citing works
“Recently, birds have emerged as models for studying the role of sleep in two classical developmental learning paradigms: imprinting in the domestic chick (Jackson et al., 2008) and song development in juvenile zebra finches (Shank & Margoliash, 2009).”
Background
Conservation of sleep: insights from non-mammalian model systems
Zimmerman, J. E., Naidoo, N. N., Raizen, D. M., & Pack, A. I. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.05.001 · Cited by 177 · see citing works
Local functional state differences between rat cortical columns
Rector, D. M., Topchiy, I., Carter, K. M., & Rojas, M. J. (2005) · Brain Research · doi:10.1016/j.brainres.2005.04.002 · Cited by 159 · see citing works
A Role for Non-Rapid-Eye-Movement Sleep Homeostasis in Perceptual Learning
Aeschbach, D., Cutler, A. J., & Ronda, J. M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.5548-07.2008 · Cited by 142 · see citing works
Sleep homeostasis in suprachiasmatic nuclei-lesioned rats: effects of sleep deprivation and triazolam administration
Trachsel, L., Edgar, D. M., Seidel, W. F., & Heller, H. C. (1992) · Brain Research · doi:10.1016/0006-8993(92)91284-l · Cited by 127 · see citing works
Effect of forced locomotion on the rest-activity cycle of the cockroach
Tobler, I. (1983) · Behavioural Brain Research · doi:10.1016/0166-4328(83)90180-8 · Cited by 120 · see citing works
Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons
Rao, Y., Liu, Z.-W., Borók, E., Rabenstein, R. L., Shanabrough, M., Lu, M., Picciotto, M. R., Horváth, T. L., & Gao, X. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32829 · Cited by 117 · see citing works
The Parable of Parabola: What the U-Shaped Curve Can and Cannot Tell Us about Sleep
Bliwise, D. L., & Young, T. B. (2007) · SLEEP · doi:10.1093/sleep/30.12.1614 · Cited by 111 · see citing works
Performance and sleepiness following moderate sleep disruption and slow wave sleep deprivation
Bonnet, M. H. (1986) · Physiology & Behavior · doi:10.1016/s0031-9384(86)80012-9 · Cited by 108 · see citing works
Slow Wave Sleep and REM Sleep Awakenings Do Not Affect Sleep Dependent Memory Consolidation
Genzel, L., Dresler, M., Wehrle, R., Grözinger, M., & Steiger, A. (2009) · Sleep · doi:10.1093/sleep/32.3.302 · Cited by 107 · see citing works
Retinoic Acid Signaling Affects Cortical Synchrony During Sleep
Maret, S., Franken, P., Dauvilliers, Y. A., Ghyselinck, N. B., Chambon, P., & Tafti, M. (2005) · Science · doi:10.1126/science.1117623 · Cited by 107 · see citing works
Cellular mechanisms of burst firing‐mediated long‐term depression in rat neocortical pyramidal cells
Czarnecki, A., Birtoli, B., & Ulrich, D. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.123588 · Cited by 99 · see citing works
Firing Mode-Dependent Synaptic Plasticity in Rat Neocortical Pyramidal Neurons
Birtoli, B., & Ulrich, D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0795-04.2004 · Cited by 97 · see citing works
Abnormal sleep and sleepiness in Parkinson's disease
Arnulf, I., Leu‐Semenescu, S., & Oudiette, D. (2008) · Current Opinion in Neurology · doi:10.1097/wco.0b013e328305044d · Cited by 96 · see citing works
Sleep-Dependent Plasticity Requires Cortical Activity
Jha, S. K., Jones, B. E., Coleman, T., Steinmetz, N., Law, C.-T., Griffin, G., Hawk, J., Dabbish, N., Kalatsky, V. A., & Frank, M. G. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2722-05.2005 · Cited by 96 · see citing works
Sleep function
Krueger, J. M. (2003) · Frontiers in bioscience · doi:10.2741/1031 · Cited by 94 · see citing works
Dynamics of a Memory Trace: Effects of Sleep on Consolidation
Jackson, C., McCabe, B. J., Nicol, A. U., Grout, A. S., Brown, M. W., & Horn, G. (2008) · Current Biology · doi:10.1016/j.cub.2008.01.062 · Cited by 88 · see citing works
Perinatal changes in expression of aquaporin‐4 and other water and ion transporters in rat lung
Yasui, M., Serlachius, E., Löfgren, M., Belusa, R., Nielsen, S., & Aperia, A. C. (1997) · The Journal of Physiology · doi:10.1111/j.1469-7793.1997.003bc.x · Cited by 85 · see citing works
Adenosine as a Biological Signal Mediating Sleepiness following Prolonged Wakefulness
Basheer, R., Porkka‐Heiskanen, T., Strecker, R. E., Thakkar, M. M., & McCarley, R. W. (2000) · Neurosignals · doi:10.1159/000014655 · Cited by 81 · see citing works
The Upshot of Up States in the Neocortex: From Slow Oscillations to Memory Formation
Hoffman, K., Battaglia, F., Harris, K., MacLean, J., Marshall, L., & Mehta, M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3501-07.2007 · Cited by 72 · see citing works
The Wake-Promoting Hypocretin/Orexin Neurons Change Their Response to Noradrenaline after Sleep Deprivation
Grivel, J., Cvetkovic, V., Bayer, L., Machard, D., Tobler, I., Mühlethaler, M., & Serafin, M. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0666-05.2005 · Cited by 69 · see citing works
A network model for activity-dependent sleep regulation
Roy, S., Krueger, J. M., Rector, D. M., & Wan, Y. (2008) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2008.03.033 · Cited by 56 · see citing works
Slow-wave sleep, diabetes, and the sympathetic nervous system
Dijk, D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711635105 · Cited by 44 · see citing works
Self-citation
Narcolepsy: pathophysiology and pharmacology.
Nishino, S. (2007) · PubMed · Cited by 39 · see citing works
Suprachiasmatic Modulation of Noradrenaline Release in the Ventrolateral Preoptic Nucleus
Saint-Mleux, B., Bayer, L., Eggermann, E., Jones, B. E., Mühlethaler, M., & Serafin, M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1432-07.2007 · Cited by 28 · see citing works
Sleep does not enhance the recovery of deprived eye responses in developing visual cortex
Dadvand, L., Stryker, M. P., & Frank, M. G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.029 · Cited by 17 · see citing works
Still Missing Some Significant Ingredients
Schabus, M. (2009) · SLEEP · doi:10.1093/sleep/32.3.291 · Cited by 17 · see citing works
Sleeping Our Way to Weight Normalization and Stable Learning
Sullivan, T. J., & de Sa, V. R. (2008) · Neural Computation · doi:10.1162/neco.2008.04-07-502 · Cited by 12 · see citing works

Flagged first, then by citations

Research works printed but not linked: 1

Anderson, M.P., Mochizuki, T., Xie, J., Fischler, W., Manger, J.P., Talley, E.M., Scammell, T.E. & Tonegawa, S. (2005) Thalamic Cav3.1 T-type Ca2 + channel plays a crucial role in stabilizing sleep. Proc. Natl Acad. Sci. USA , 102 , 1743-1748.

Sorted by citations

EEG delta oscillations as a correlate of basic homeostatic and motivational processes
Knyazev, G. G. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.10.002 · Cited by 776 · see citing works
Electroencephalography of response inhibition tasks: Functional networks and cognitive contributions
Huster, R. J., Enriquez‐Geppert, S., Lavallee, C. F., Falkenstein, M., & Herrmann, C. S. (2012) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2012.08.001 · Cited by 744 · see citing works
Sleep and the single neuron: the role of global slow oscillations in individual cell rest
Vyazovskiy, V. V., & Harris, K. D. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3494 · Cited by 362 · see citing works
Impaired Insulin Signaling in Human Adipocytes After Experimental Sleep Restriction: A Randomized, Crossover Study
Broussard, J. L., Ehrmann, D. A., Van Cauter, E., Tasali, E., & Brady, M. J. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-8-201210160-00005 · Cited by 364 · see citing works
EEG microstates of wakefulness and NREM sleep
Brodbeck, V., Kuhn, A., von Wegner, F., Morzelewski, A., Tagliazucchi, E., Borisov, S. V., Michel, C. M., & Laufs, H. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.05.060 · Cited by 292 · see citing works
Quantitative phosphoproteomic analysis of the molecular substrates of sleep need
Wang, Z., Ma, J., Miyoshi, C., Li, Y., Sato, M., Ogawa, Y., Lou, T., Ma, C., Gao, X., Lee, C.-Y., et al. (2018) · Nature · doi:10.1038/s41586-018-0218-8 · Cited by 246 · see citing works
Modelling changes in sleep timing and duration across the lifespan: changes in circadian rhythmicity or sleep homeostasis?
Skeldon, A. C., Derks, G., & Dijk, D.-J. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.05.011 · Cited by 165 · see citing works
Self-citation
Sleep, recovery, and metaregulation: explaining the benefits of sleep
Vyazovskiy, V. V. (2015) · Nature and Science of Sleep · doi:10.2147/nss.s54036 · Cited by 151 · see citing works
Variation in sleep behaviour in free-living blue tits, Cyanistes caeruleus: effects of sex, age and environment
Steinmeyer, C., Schielzeth, H., Mueller, J. C., & Kempenaers, B. (2010) · Animal Behaviour · doi:10.1016/j.anbehav.2010.08.005 · Cited by 122 · see citing works
Sleep Disturbance Impairs Stroke Recovery in the Rat
Zunzunegui, C., Gao, B., Cam, E., Hodor, A., & Bassetti, C. L. (2011) · SLEEP · doi:10.5665/sleep.1252 · Cited by 119 · see citing works
Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need
Vassalli, A., & Franken, P. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1700983114 · Cited by 117 · see citing works
Self-citation
A Neocortical Delta Rhythm Facilitates Reciprocal Interlaminar Interactions via Nested Theta Rhythms
Carracedo, L. M., Kjeldsen, H., Cunnington, L. G., Jenkins, A., Schofield, I. S., Cunningham, M. O., Davies, C. H., Traub, R. D., & Whittington, M. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0735-13.2013 · Cited by 113 · see citing works
A before and after comparison of the effects of forest walking on the sleep of a community-based sample of people with sleep complaints
Morita, E., Imai, M., Okawa, M., Miyaura, T., & Miyazaki, S. (2011) · BioPsychoSocial Medicine · doi:10.1186/1751-0759-5-13 · Cited by 109 · see citing works
Orexin Receptor Antagonism, a New Sleep-Promoting Paradigm: An Ascending Single-Dose Study With Almorexant
Hoever, P., de Haas, S., Winkler, J., Schoemaker, R. C., Chiossi, E., van Gerven, J., & Dingemanse, J. (2010) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2010.19 · Cited by 100 · see citing works
Birdsong memory and the brain: In search of the template
Bolhuis, J. J., & Moorman, S. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.019 · Cited by 84 · see citing works
Understanding the interplay of sleep and aging: Methodological challenges
Muehlroth, B. E., & Werkle‐Bergner, M. (2020) · Psychophysiology · doi:10.1111/psyp.13523 · Cited by 80 · see citing works
Functional anatomy of non-REM sleep
de Andrés, I. (2011) · Frontiers in Neurology · doi:10.3389/fneur.2011.00070 · Cited by 84 · see citing works
Do sleep, stress, and illness explain daily variations in fatigue? A prospective study
Åkerstedt, T., Axelsson, J., Lekander, M., Orsini, N., & Kecklund, G. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.01.005 · Cited by 78 · see citing works
Slow-wave sleep deficiency and enhancement: Implications for insomnia and its management
Dijk, D. (2010) · The World Journal of Biological Psychiatry · doi:10.3109/15622971003637645 · Cited by 75 · see citing works
Self-citation
Sleep smart—optimizing sleep for declarative learning and memory
Feld, G. B., & Diekelmann, S. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.00622 · Cited by 74 · see citing works
Fibromyalgia and Sleep
Spaeth, M., Rizzi, M., & Sarzi‐Puttini, P. (2011) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2011.03.004 · Cited by 72 · see citing works
Telomere length as a marker of sleep loss and sleep disturbances: a potential link between sleep and cellular senescence
Tempaku, P. F., Mazzotti, D. R., & Tufik, S. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.02.519 · Cited by 62 · see citing works
Gender differences in sleep patterns and sleep complaints of elite athletes.
Silva, A., Narciso, F. V., Rosa, J. P., Rodrigues, D. F., Cruz, A. Â. D. S., Tufik, S., Viana, F., Bichara, J. J., Pereira, S. R. D., da Silva, S. C., et al. (2019) · PubMed Central · doi:10.5935/1984-0063.20190084 · Cited by 59 · see citing works
The Effects of Music Intervention on Sleep Quality in Community-Dwelling Elderly
Wang, Q., Chair, S. Y., Wong, E. M. L., & Li, X. (2016) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2015.0304 · Cited by 55 · see citing works
Clinical Pharmacology in Sleep Medicine
Proctor, A. R., & Bianchi, M. T. (2012) · ISRN Pharmacology · doi:10.5402/2012/914168 · Cited by 50 · see citing works
Sleep Misperception in Healthy Adults: Implications for Insomnia Diagnosis
Bianchi, M. T., Wang, W., & Klerman, E. B. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.2154 · Cited by 44 · see citing works
Whole blood genome-wide gene expression profile in males after prolonged wakefulness and sleep recovery
Pellegrino, R., Sunaga, D. Y., Guindalini, C., Martins, R. C. S., Mazzotti, D. R., Wei, Z., Daye, Z. J., Andersen, M. L., & Tufik, S. (2012) · Physiological Genomics · doi:10.1152/physiolgenomics.00058.2012 · Cited by 42 · see citing works
Sleep in athletes and the effects of Ramadan
Roky, R., Herrera, C. P., & Ahmed, Q. A. A. (2012) · Journal of Sports Sciences · doi:10.1080/02640414.2012.693622 · Cited by 45 · see citing works
Sleep-Wake Disturbance: A Systematic Review of Evidence-Based Interventions for Management in Patients With Cancer
Matthews, E. E., Carter, P. A., Page, M., Dean, G. E., & Berger, A. M. (2018) · Clinical journal of oncology nursing · doi:10.1188/18.cjon.37-52 · Cited by 40 · see citing works
Baclofen facilitates sleep, neuroplasticity, and recovery after stroke in rats
Hodor, A., Palchykova, S., Baracchi, F., Noaín, D., & Bassetti, C. L. (2014) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.115 · Cited by 41 · see citing works
Calidad de sueño y somnolencia diurna excesiva en estudiantes universitarios de diferentes dominios
Maya, S. D. L. P., Lubert, C. D., Londoño, D. M. M., Chaurra, J. T., & Osorio, L. S. N. (2018) · Hacia la Promoción de la Salud · doi:10.17151/hpsal.2019.24.1.8 · Cited by 35 · see citing works
Emotional Climate and Behavioral Management during Sleep Time in Early Childhood Education Settings
Pattinson, C. L., Staton, S., Smith, S. S., Sinclair, D. M., & Thorpe, K. J. (2014) · Early Childhood Research Quarterly · doi:10.1016/j.ecresq.2014.07.009 · Cited by 35 · see citing works
A Molecular Basis for Interactions Between Sleep and Memory
Hernandez, P. J., & Abel, T. G. (2011) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2010.12.004 · Cited by 35 · see citing works
Sleep, cognition and cortisol in addison’s disease: a mechanistic relationship
Henry, M., Thomas, K. G. F., & Ross, I. L. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.694046 · Cited by 34 · see citing works
Neurophysiology of circadian rhythm sleep disorders of children with neurodevelopmental disabilities
Jan, J. E., BAX, M. C. O., Owens, J. A., Ipsiroglu, O., & Wasdell, M. B. (2012) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2012.01.002 · Cited by 32 · see citing works
“Do I really need a nap?”: The role of sleep science in informing sleep practices in early childhood education and care settings.
Staton, S., Smith, S. S., & Thorpe, K. J. (2015) · Translational Issues in Psychological Science · doi:10.1037/tps0000011 · Cited by 31 · see citing works
To sleep or not to sleep – Effects on memory in normal aging and disease
Kroeger, D., & Vetrivelan, R. (2023) · Aging Brain · doi:10.1016/j.nbas.2023.100068 · Cited by 25 · see citing works
Assessment of SOMNOwatch plus EEG for sleep monitoring in healthy individuals
Voinescu, B., Wisłowska, M., & Schabus, M. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.04.052 · Cited by 23 · see citing works
Sleep: A behavioral account.
Blampied, N. M., & Bootzin, R. R. (2012) · American Psychological Association eBooks · doi:10.1037/13938-017 · Cited by 21 · see citing works
Sleep Quality Improvement and Exercise: A Review
ZubiaVeqar, M. E. (2012) · Cited by 18 · see citing works
Sleep Quality: A Key Factor in the Physical and Mental Recovery of Medical Students
González‐Argote, J., & Sánchez, A. A. L. (2022) · Rehabilitation and Sports Medicine · doi:10.56294/ri202221 · Cited by 18 · see citing works
What parents want: parent preference regarding sleep for their preschool child when attending early care and education
Sinclair, D. M., Staton, S., Smith, S. S., Pattinson, C. L., Marriott, A., & Thorpe, K. J. (2015) · Sleep Health · doi:10.1016/j.sleh.2015.11.002 · Cited by 17 · see citing works
Neuropsychiatric symptoms and altered sleep quality in cerebral small vessel disease
Li, X., Qin, R.-R., Chen, J., Jiang, H., Tang, P., Wang, Y., Xu, D., Xu, T., & Yuan, T. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.882922 · Cited by 15 · see citing works
Neurobiología del sueño y su importancia: antología para el estudiante universitario
Carrillo-Mora, P. U., Ramírez-Peris, J., & Magaña-Vázquez, K. (2013) · Revista de la Facultad de Medicina (México) · Cited by 18 · see citing works
Cortical–Subcortical Interactions in Hypersomnia Disorders: Mechanisms Underlying Cognitive and Behavioral Aspects of the Sleep–Wake Cycle
Larson‐Prior, L. J., Ju, Y. S., & Galvin, J. E. (2014) · Frontiers in Neurology · doi:10.3389/fneur.2014.00165 · Cited by 15 · see citing works
Assessment of Dietary and Lifestyle Quality among the Romanian Population in the Post-Pandemic Period
Mititelu, M., Popovici, V., Neacșu, S. M., Musuc, A. M., Busnatu, Ș., Oprea, E., Boroghină, S. C., Mihai, A., Streba, C. T., Lupuliasa, D., et al. (2024) · Healthcare · doi:10.3390/healthcare12101006 · Cited by 13 · see citing works
Reflexology and polysomnography: Changes in cerebral wave activity induced by reflexology promote N1 and N2 sleep stages
Esmel-Esmel, N., Tomás-Esmel, E., Tous-Andreu, M., Bové-Ribé, A., & Herrera, M. (2017) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2017.05.003 · Cited by 13 · see citing works
Thermoregulation and Sleep: Functional Interaction and Central Nervous Control
Cerri, M., & Amici, R. (2021) · Comprehensive physiology · doi:10.1002/cphy.c140012 · Cited by 21 · see citing works
Evaluation of Sleep Quality and Daytime Sleepiness in Dentistry Students
Angelin, T. J., Mota, K. R., dos Santos, V. E., Cosme‐Silva, L., & Heimer, M. V. (2020) · Pesquisa Brasileira em Odontopediatria e Clínica Integrada · doi:10.1590/pboci.2020.122 · Cited by 12 · see citing works
Dorsal vs. ventral differences in fast Up-state-associated oscillations in the medial prefrontal cortex of the urethane-anesthetized rat
Gretenkord, S., Rees, A., Whittington, M. A., Gartside, S. E., & LeBeau, F. E. N. (2016) · Journal of Neurophysiology · doi:10.1152/jn.00762.2016 · Cited by 12 · see citing works
Sleeping Our Way to Weight Normalization and Stable Learning
Sullivan, T. J., & de Sa, V. R. (2008) · Neural Computation · doi:10.1162/neco.2008.04-07-502 · Cited by 12 · see citing works
The functions of sleep
Franken, P., Kopp, C., Landolt, H., & Lüthi, A. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06746.x · Cited by 12 · see citing works
Poor quality of sleep in Mexican patients with type 2 diabetes and its association with lack of glycemic control
Suárez-Torres, I., García‐García, F., Morales‐Romero, J., Melgarejo-Gutiérrez, M. A., Demeneghi-Marini, V. P., Luna-Ceballos, R. I., Trejo, C. H., & Cortés, D. A. C. (2023) · Primary care diabetes · doi:10.1016/j.pcd.2023.01.011 · Cited by 11 · see citing works
Dynamism in Activity of the Neural Networks in Brain is the Basis of Sleep-Wakefulness Oscillations
Gulia, K. K. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00038 · Cited by 10 · see citing works
Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory
Maywood, E. S., Chesham, J. E., Winsky‐Sommerer, R., Smyllie, N. J., & Hastings, M. H. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.639281 · Cited by 10 · see citing works
Thermoregulation and Sleep: Functional Interaction and Central Nervous Control
Cerri, M., & Amici, R. (2021) · Comprehensive physiology · doi:10.1002/j.2040-4603.2021.tb00151.x · Cited by 9 · see citing works
Polypharmacologicalin SilicoBioactivity Profiling and Experimental Validation Uncovers Sedative-Hypnotic Effects of Approved and Experimental Drugs in Rat
Drakakis, G., Wafford, K. A., Brewerton, S. C., Bodkin, M. J., Evans, D. A. P., & Bender, A. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.7b00209 · Cited by 9 · see citing works
Identification of a rapid eye movement sleep window for learning of the win-shift radial arm maze task for male Sprague-Dawley rats: Sleep duration and psychiatric disorders
LEGAULT, G., DELAY, S., & MADORE, A. (2010) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2010.00842.x · Cited by 9 · see citing works
Automated Observations of Dogs’ Resting Behaviour Patterns Using Artificial Intelligence and Their Similarity to Behavioural Observations
Schork, I. G., Zamansky, A., Farhat, N., de Azevedo, C. S., & Young, R. J. (2024) · Animals · doi:10.3390/ani14071109 · Cited by 8 · see citing works
Theta Oscillations Alternate With High Amplitude Neocortical Population Within Synchronized States
Munro, E., Sakata, S., & Toyoizumi, T. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00316 · Cited by 8 · see citing works
The evolutionary origin of the need to sleep: an inevitable consequence of synaptic neurotransmission?
Cantor, R. S. (2015) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2015.00015 · Cited by 8 · see citing works
Noninvasive sleep monitoring in large-scale screening of knock-out mice reveals novel sleep-related genesPreprint
Joshi, S., Sethi, M., Striz, M., Cole, N., Denegre, J. M., Ryan, J. L., Lhamon, M. E., Agarwal, A., Murray, S. A., Braun, R. E., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/517680 · Cited by 7 · see citing works
Instrumental learning: An animal model for sleep dependent memory enhancement
Leenaars, C. H. C., Girardi, C. E. N., Joosten, R. N. J. M. A., Lako, I. M., Ruimschotel, E., Hanegraaf, M. A. J., Demattéis, M., Feenstra, M. G. P., & Someren, E. J. W. V. (2013) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2013.04.003 · Cited by 6 · see citing works
Sleep in intensive care units
Malik, V., & Parthasarathy, S. (2014) · Current Respiratory Care Reports · doi:10.1007/s13665-014-0077-1 · Cited by 6 · see citing works
Seven Survival Senses: Evolutionary Training Makes Discerning Differences More Natural than Spotting SimilaritiesPreprint
Kashyap, R. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3270726 · Cited by 6 · see citing works
Corrigendum: Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory
Maywood, E. S., Chesham, J. E., Winsky‐Sommerer, R., Smyllie, N. J., & Hastings, M. H. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.740799 · Cited by 6 · see citing works
The Genetics of Sleep in Drosophila
Singh, N. P., Ghosh, A., & Harbison, S. T. (2024) · Springer eBooks · doi:10.1007/978-3-031-62723-1_2 · Cited by 5 · see citing works
Functions of Sleep and NREMS
Moorcroft, W. H. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6467-9_10 · Cited by 5 · see citing works
Older cerebral small vessel disease and sleep disturbance: A diffusion tensor imaging study
Gu, Y., Feng, W., Tian, X., Wang, X., & Li, X. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.01.028 · Cited by 5 · see citing works
Sleep and Cancer
Berger, A. M., Matthews, E. E., & Aloia, M. S. (2018) · Springer eBooks · doi:10.1007/978-3-319-90990-5_4 · Cited by 4 · see citing works
Sleep hygiene and good sleep habits: A review
Prasad, R., & Pandey, A. K. (2012) · Indian Journal of Sleep Medicine · doi:10.5958/j.0974-0155.7.4.020 · Cited by 3 · see citing works
Association between screen time, physical activity and sleep quality among youths
Liu, G., & Liu, D. (2023) · International Journal of Public Health Science (IJPHS) · doi:10.11591/ijphs.v12i3.23098 · Cited by 3 · see citing works
The sleep-like nature of early mammalian behavioral rhythms: Theoretical comment on Todd et al. (2010).
Corner, M. A. (2010) · Behavioral Neuroscience · doi:10.1037/a0018483 · Cited by 3 · see citing works
Genetics of Circadian Rhythm Disorders
Chang, A., & Zee, P. C. (2011) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2011.03.002 · Cited by 3 · see citing works
Exploring the Mediating Role of Sleep Deficit-Related Functional Status in Subacute Stroke Survivors
Kumar, S., Parveen, S., Manzar, M. D., Alghadir, A. H., Khan, M., Al-Quliti, K. W., Spence, D. W., Pandi-Perumal, S. R., BaHammam, A. S., & Noohu, M. M. (2024) · Medicina · doi:10.3390/medicina60030422 · Cited by 3 · see citing works
Basic Circadian Timing and Sleep-Wake Regulation
Cuesta, M., Boudreau, P., & Boivin, D. B. (2017) · Springer eBooks · doi:10.1007/978-1-4939-6578-6_6 · Cited by 3 · see citing works
Studying the interplay of sleep and aging: Methodological challengesPreprint
Muehlroth, B. E., & Werkle‐Bergner, M. (2019) · MPG.PuRe (Max Planck Society) · Cited by 3 · see citing works
Sleep prevents brain phosphoproteome disruption to safeguard survival
Ma, J., Liu, J., Li, Y., Zhao, Y., Tian, Y., Hu, B., Yan, K., Li, Y., Ding, K., Wang, X., et al. (2025) · Cell Discovery · doi:10.1038/s41421-025-00809-w · Cited by 2 · see citing works
Characteristics of integrative brain activity during various stages of sleep and in transitional states
An, S., Tsitseroshin, M. N., Galperina, E. I., Рожков, В. П., Kruchinina, O. V., Zaitseva, L. G., & Panasevich, E. A. (2012) · Human Physiology · doi:10.1134/s0362119712030127 · Cited by 2 · see citing works
The Multifunctionality of Dreaming and the Oblivious Avatar
Dresler, M. (2015) · doi:10.15502/9783958570672 · Cited by 2 · see citing works
Seven Survival Senses: Evolutionary Training Makes Discerning Differences More Natural Than Spotting Similarities
Kashyap, R. (2018) · World Futures : Journal of General Evolution · doi:10.1080/02604027.2020.1859315 · Cited by 3 · see citing works
Understanding the interplay of sleep and aging: Methodological challengesPreprint
Muehlroth, B. E., & Werkle-Bergner, M. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/713552 · Cited by 2 · see citing works
Characteristics and neuronal correlates of superior memory performance
Konrad, B. N. (2014) · Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München) · doi:10.5282/edoc.16636 · Cited by 2 · see citing works
About a possible role of parasomnias as a factor of stabilization of sleep cycles
An, S., & Golbin, A. (2009) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093009060064 · Cited by 1 · see citing works
Sleep After Traumatic Brain Injury
Congiu, P., Puligheddu, M., Figorilli, M., Mondello, S., & Ferri, R. (2020) · Springer eBooks · doi:10.1007/978-3-030-54359-4_16 · Cited by 1 · see citing works
Distrés psicológico y calidad de sueño: Un estudio transversal en estudiantes universitarios
Universidad Nacional Amazónica de Madre de Dios, P., & Estrada-Araoz, E. G. (2024) · Gaceta Médica de Caracas · doi:10.47307/gmc.2024.132.1.3 · Cited by 1 · see citing works
Sleepiness in the military: operational implications and research imperatives
Balkin, T. J. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511762697.022 · Cited by 1 · see citing works
EVALUATION OF NUTRITIONAL STATUS AND ADHERENCE TO A HEALTHY DIET AMONG THE ROMANIAN POPULATION
Mititelu, M. (2023) · FARMACIA · doi:10.31925/farmacia.2023.5.13 · Cited by 1 · see citing works
Sleep and Circadian Rhythms
Mistlberger, R. E. (2015) · Wiley eBooks · doi:10.1002/9781118467831.ch4 · Cited by 1 · see citing works
Tracking brain dynamics across transitions of consciousness
Comșa, I. M. (2018) · Apollo (University of Cambridge) · doi:10.17863/cam.37723 · Cited by 1 · see citing works
Sleep deprivation in rats: effects on learning and cognitive flexibility
Leenaars, C. H. C. (2013) · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)
A expressão de genes relacionados à plasticidade sináptica durante o sono REM após exposição a um ambiente enriquecido
Pinto, J. B. C. C. (2010) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.47.2010.tde-12032010-155559
QUALITY OF LIFE AND PSYCHOLOGICAL FUNCTIONING IN OBSERVATIONAL AND INTERVENTION STUDIES IN CHILDHOOD MIGRAINE
Bruijn, J. (2026) · EUR Research Repository (Erasmus University Rotterdam) · doi:10.13140/rg.2.2.30516.41600
The Brain in Sleep
Moorcroft, W. H. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6467-9_5
Delta Rhythms: Models and Physiology
Traub, R. D., & Whittington, M. A. (2015) · Springer eBooks · doi:10.1007/978-1-4614-6675-8_305
Conscious Modulation in Normal Sleep
Salín-Pascual, R. J. (2011) · The Open Sleep Journal · doi:10.2174/1874620901104010001
Variation in sleep behaviour and its underlying causes: a study in a free-living blue tit population
Loës, C. (2012)
The Functions of REMS and Dreaming
Moorcroft, W. H. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6467-9_11
Sleep habits and associated phenomenon in Indian adults
Tripathi, M., Sharma, V. K., & Dwivedi, S. N. (2010) · Indian Journal of Sleep Medicine · doi:10.5005/ijsm-5-2-54
Testing predictions from the synaptic homeostasis hypothesis: A sleep deprivation study of cortical thickness and visual evoked potentials
Norbom, L. B. (2013) · NORA - Norwegian Open Research Archives

Local Use-Dependent Sleep
Krueger, J., & Wisor, J. (2011) · Current Topics in Medicinal Chemistry · doi:10.2174/156802611797470295 · Cited by 45 · see citing works
Local Sleep
Vyazovskiy, V. V., & Andrillon, T. (2025) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197602751.013.39
Local sleep: A new concept in brain plasticity
Avvenuti, G., & Bernardi, G. (2022) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819410-2.00003-5 · Cited by 9 · see citing works
Behavioral and Electrophysiological Correlates of Sleep and Sleep Homeostasis
Deboer, T. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2013_248 · Cited by 73 · see citing works
Oscillating circuitries in the sleeping brain
Adamantidis, A. R., Gutierrez Herrera, C., & Gent, T. C. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0223-4 · Cited by 281 · see citing works

Authors: Vassalli, A., & Dijk, D.
Affiliations: University of Lausanne (CH)
University of Surrey (GB)
ORCID: Vassalli, Anne
Dijk, Derk‐Jan
Venue: European Journal of Neuroscience
Publisher: Wiley
Published: 2009-05
Volume: 29
Issue: 9
Pages: 1830-1841
ISSN: 0953-816X (ISSN-L)
1460-9568
DOI: 10.1111/j.1460-9568.2009.06767.x
OpenAlex: W1979724295
Cited by: 110
References: 114
Citations by year: 2026: 1 · 2025: 2 · 2024: 6 · 2023: 4 · 2022: 5 · 2021: 8 · 2020: 3 · 2019: 6 · 2018: 7 · 2017: 4 · 2016: 2 · 2015: 11 · 2014: 9 · 2013: 9 · 2012: 14
FWCI: 0.81
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: European Journal of Neuroscience (publishedVersion)
PubMed (publishedVersion)
SERVAL (Université de Lausanne) (publishedVersion, other-oa)
IRIS (submittedVersion)
Open Research (University of Surrey) (submittedVersion)
Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
Funders: Wellcome Trust
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Directorate for Biological Sciences
Biotechnology and Biological Sciences Research Council
Air Force Office of Scientific Research
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
Keywords: sleep function, sleep homeostasis, sleep-wake states, wakefulness, NREM sleep, REM sleep, slow-wave activity, network connectivity, memory consolidation, sleep regulation, top-down control
MeSH terms: Aging, Animals, Brain, Circadian Rhythm, Female, Homeostasis, Humans, Male, Memory, Neuronal Plasticity, Neurons, Sex Characteristics, Sleep, Synapses

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sleep function: current questions and new approaches

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks